Should you encounter any unexpected behaviour,
please let us know.

* floflo3 *

CA strain for 2403041948001590542

--- normal mode 13 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
LYS 23 LYS 24 0.0002

LYS 24 VAL 25 0.0004

VAL 25 LEU 26 0.0001

LEU 26 THR 27 -0.0002

THR 27 LEU 28 0.0002

LEU 28 GLU 29 0.0003

GLU 29 GLY 30 0.0002

GLY 30 ASP 31 -0.0003

ASP 31 LEU 32 -0.0002

LEU 32 VAL 33 0.0001

VAL 33 LEU 34 -0.0002

LEU 34 GLY 35 0.0003

GLY 35 GLY 36 -0.0006

GLY 36 LEU 37 -0.0002

LEU 37 PHE 38 0.0000

PHE 38 PRO 39 -0.0002

PRO 39 VAL 40 -0.0004

VAL 40 HIS 41 0.0002

HIS 41 GLN 42 0.0001

GLN 42 LYS 43 -0.0002

LYS 43 GLY 44 -0.0001

GLY 44 GLY 45 0.0002

GLY 45 PRO 46 -0.0002

PRO 46 ALA 47 -0.0001

ALA 47 GLU 48 -0.0003

GLU 48 ASP 49 0.0019

ASP 49 CYS 50 -0.0003

CYS 50 GLY 51 0.0002

GLY 51 PRO 52 0.0001

PRO 52 VAL 53 -0.0003

VAL 53 ASN 54 -0.0003

ASN 54 GLU 55 0.0003

GLU 55 HIS 56 0.0000

HIS 56 ARG 57 -0.0001

ARG 57 GLY 58 -0.0001

GLY 58 ILE 59 -0.0001

ILE 59 GLN 60 0.0000

GLN 60 ARG 61 0.0001

ARG 61 LEU 62 -0.0003

LEU 62 GLU 63 -0.0000

GLU 63 ALA 64 -0.0000

ALA 64 MET 65 -0.0001

MET 65 LEU 66 0.0002

LEU 66 PHE 67 0.0004

PHE 67 ALA 68 -0.0001

ALA 68 LEU 69 0.0003

LEU 69 ASP 70 0.0002

ASP 70 ARG 71 -0.0000

ARG 71 ILE 72 -0.0001

ILE 72 ASN 73 0.0000

ASN 73 ARG 74 0.0003

ARG 74 ASP 75 0.0003

ASP 75 PRO 76 0.0002

PRO 76 HIS 77 0.0000

HIS 77 LEU 78 -0.0002

LEU 78 LEU 79 0.0002

LEU 79 PRO 80 0.0000

PRO 80 GLY 81 0.0000

GLY 81 VAL 82 -0.0003

VAL 82 ARG 83 0.0002

ARG 83 LEU 84 0.0005

LEU 84 GLY 85 -0.0004

GLY 85 ALA 86 0.0001

ALA 86 HIS 87 0.0000

HIS 87 ILE 88 -0.0003

ILE 88 LEU 89 0.0001

LEU 89 ASP 90 -0.0001

ASP 90 SER 91 -0.0002

SER 91 CYS 92 0.0002

CYS 92 SER 93 -0.0001

SER 93 LYS 94 0.0003

LYS 94 ASP 95 -0.0003

ASP 95 THR 96 0.0004

THR 96 HIS 97 -0.0000

HIS 97 ALA 98 -0.0002

ALA 98 LEU 99 0.0001

LEU 99 GLU 100 0.0002

GLU 100 GLN 101 -0.0014

GLN 101 ALA 102 0.0005

ALA 102 LEU 103 -0.0001

LEU 103 ASP 104 -0.0002

ASP 104 PHE 105 -0.0001

PHE 105 VAL 106 -0.0003

VAL 106 ARG 107 -0.0002

ARG 107 ALA 108 0.0000

ALA 108 SER 109 -0.0003

SER 109 LEU 110 0.0001

LEU 110 ILE 136 0.0006

ILE 136 THR 137 0.0002

THR 137 GLY 138 0.0000

GLY 138 VAL 139 0.0001

VAL 139 ILE 140 -0.0004

ILE 140 GLY 141 0.0002

GLY 141 GLY 142 -0.0003

GLY 142 SER 143 -0.0000

SER 143 TYR 144 0.0002

TYR 144 SER 145 -0.0003

SER 145 ASP 146 0.0003

ASP 146 VAL 147 -0.0002

VAL 147 SER 148 0.0001

SER 148 ILE 149 0.0014

ILE 149 GLN 150 -0.0001

GLN 150 VAL 151 0.0000

VAL 151 ALA 152 -0.0002

ALA 152 ASN 153 0.0001

ASN 153 LEU 154 -0.0000

LEU 154 LEU 155 -0.0002

LEU 155 ARG 156 -0.0002

ARG 156 LEU 157 -0.0001

LEU 157 PHE 158 0.0002

PHE 158 GLN 159 0.0001

GLN 159 ILE 160 0.0002

ILE 160 PRO 161 -0.0000

PRO 161 GLN 162 -0.0006

GLN 162 ILE 163 -0.0001

ILE 163 SER 164 0.0001

SER 164 TYR 165 -0.0000

TYR 165 ALA 166 -0.0001

ALA 166 SER 167 -0.0002

SER 167 THR 168 -0.0001

THR 168 SER 169 0.0001

SER 169 ALA 170 0.0002

ALA 170 LYS 171 0.0004

LYS 171 LEU 172 -0.0003

LEU 172 SER 173 -0.0001

SER 173 ASP 174 0.0002

ASP 174 LYS 175 -0.0004

LYS 175 SER 176 -0.0002

SER 176 ARG 177 -0.0001

ARG 177 TYR 178 -0.0001

TYR 178 ASP 179 0.0000

ASP 179 TYR 180 -0.0002

TYR 180 PHE 181 -0.0004

PHE 181 ALA 182 0.0003

ALA 182 ARG 183 -0.0002

ARG 183 THR 184 0.0003

THR 184 VAL 185 0.0001

VAL 185 PRO 186 0.0001

PRO 186 PRO 187 -0.0002

PRO 187 ASP 188 -0.0049

ASP 188 PHE 189 -0.0003

PHE 189 PHE 190 -0.0000

PHE 190 GLN 191 0.0001

GLN 191 ALA 192 0.0003

ALA 192 LYS 193 -0.0001

LYS 193 ALA 194 -0.0003

ALA 194 MET 195 -0.0001

MET 195 ALA 196 0.0001

ALA 196 GLU 197 0.0000

GLU 197 ILE 198 -0.0002

ILE 198 LEU 199 -0.0002

LEU 199 ARG 200 -0.0003

ARG 200 PHE 201 -0.0025

PHE 201 PHE 202 -0.0004

PHE 202 ASN 203 -0.0001

ASN 203 TRP 204 -0.0003

TRP 204 THR 205 0.0001

THR 205 TYR 206 -0.0002

TYR 206 VAL 207 0.0004

VAL 207 SER 208 -0.0002

SER 208 THR 209 -0.0001

THR 209 VAL 210 0.0001

VAL 210 ALA 211 -0.0003

ALA 211 SER 212 0.0002

SER 212 GLU 213 -0.0001

GLU 213 GLY 214 -0.0048

GLY 214 ASP 215 -0.0002

ASP 215 TYR 216 0.0001

TYR 216 GLY 217 -0.0002

GLY 217 GLU 218 -0.0001

GLU 218 THR 219 -0.0002

THR 219 GLY 220 0.0000

GLY 220 ILE 221 -0.0001

ILE 221 GLU 222 -0.0001

GLU 222 ALA 223 0.0003

ALA 223 PHE 224 0.0003

PHE 224 GLU 225 -0.0001

GLU 225 LEU 226 -0.0002

LEU 226 GLU 227 -0.0028

GLU 227 ALA 228 0.0004

ALA 228 ARG 229 0.0003

ARG 229 ALA 230 -0.0001

ALA 230 ARG 231 0.0002

ARG 231 ASN 232 0.0001

ASN 232 ILE 233 0.0000

ILE 233 CYS 234 -0.0005

CYS 234 VAL 235 0.0003

VAL 235 ALA 236 0.0003

ALA 236 THR 237 -0.0001

THR 237 SER 238 0.0001

SER 238 GLU 239 0.0001

GLU 239 LYS 240 -0.0201

LYS 240 VAL 241 -0.0001

VAL 241 GLY 242 0.0003

GLY 242 ARG 243 -0.0002

ARG 243 ALA 244 -0.0003

ALA 244 MET 245 -0.0002

MET 245 SER 246 -0.0000

SER 246 ARG 247 -0.0000

ARG 247 ALA 248 -0.0002

ALA 248 ALA 249 0.0003

ALA 249 PHE 250 -0.0002

PHE 250 GLU 251 0.0005

GLU 251 GLY 252 -0.0000

GLY 252 VAL 253 -0.0055

VAL 253 VAL 254 -0.0000

VAL 254 ARG 255 -0.0003

ARG 255 ALA 256 0.0002

ALA 256 LEU 257 -0.0000

LEU 257 LEU 258 0.0002

LEU 258 GLN 259 0.0003

GLN 259 LYS 260 -0.0001

LYS 260 PRO 261 0.0003

PRO 261 SER 262 -0.0002

SER 262 ALA 263 0.0001

ALA 263 ARG 264 0.0001

ARG 264 VAL 265 0.0000

VAL 265 ALA 266 -0.0006

ALA 266 VAL 267 0.0001

VAL 267 LEU 268 0.0000

LEU 268 PHE 269 0.0003

PHE 269 THR 270 0.0003

THR 270 ARG 271 -0.0003

ARG 271 SER 272 -0.0001

SER 272 GLU 273 0.0003

GLU 273 ASP 274 0.0004

ASP 274 ALA 275 0.0002

ALA 275 ARG 276 -0.0000

ARG 276 GLU 277 0.0001

GLU 277 LEU 278 -0.0002

LEU 278 LEU 279 0.0002

LEU 279 ALA 280 -0.0004

ALA 280 ALA 281 -0.0001

ALA 281 SER 282 0.0002

SER 282 GLN 283 -0.0001

GLN 283 ARG 284 -0.0002

ARG 284 LEU 285 0.0001

LEU 285 ASN 286 0.0000

ASN 286 ALA 287 0.0001

ALA 287 SER 288 0.0000

SER 288 PHE 289 0.0001

PHE 289 THR 290 0.0002

THR 290 TRP 291 0.0000

TRP 291 VAL 292 -0.0005

VAL 292 ALA 293 -0.0002

ALA 293 SER 294 0.0002

SER 294 ASP 295 -0.0001

ASP 295 GLY 296 0.0003

GLY 296 TRP 297 -0.0004

TRP 297 GLY 298 0.0004

GLY 298 ALA 299 0.0001

ALA 299 LEU 300 0.0002

LEU 300 GLU 301 -0.0001

GLU 301 SER 302 0.0003

SER 302 VAL 303 -0.0002

VAL 303 VAL 304 0.0003

VAL 304 ALA 305 -0.0006

ALA 305 GLY 306 0.0001

GLY 306 SER 307 -0.0004

SER 307 GLU 308 -0.0004

GLU 308 GLY 309 -0.0001

GLY 309 ALA 310 0.0000

ALA 310 ALA 311 -0.0001

ALA 311 GLU 312 -0.0004

GLU 312 GLY 313 -0.0002

GLY 313 ALA 314 -0.0001

ALA 314 ILE 315 0.0004

ILE 315 THR 316 -0.0000

THR 316 ILE 317 -0.0002

ILE 317 GLU 318 -0.0013

GLU 318 LEU 319 0.0002

LEU 319 ALA 320 -0.0000

ALA 320 SER 321 -0.0001

SER 321 TYR 322 0.0000

TYR 322 PRO 323 -0.0002

PRO 323 ILE 324 0.0001

ILE 324 SER 325 -0.0004

SER 325 ASP 326 0.0001

ASP 326 PHE 327 0.0002

PHE 327 ALA 328 -0.0000

ALA 328 SER 329 0.0003

SER 329 TYR 330 -0.0002

TYR 330 PHE 331 0.0001

PHE 331 GLN 332 0.0004

GLN 332 SER 333 -0.0001

SER 333 LEU 334 -0.0001

LEU 334 ASP 335 -0.0001

ASP 335 PRO 336 -0.0000

PRO 336 TRP 337 0.0000

TRP 337 ASN 338 0.0001

ASN 338 ASN 339 0.0001

ASN 339 SER 340 0.0000

SER 340 ARG 341 -0.0003

ARG 341 ASN 342 -0.0000

ASN 342 PRO 343 -0.0004

PRO 343 TRP 344 -0.0004

TRP 344 PHE 345 -0.0004

PHE 345 ARG 346 0.0003

ARG 346 GLU 347 -0.0001

GLU 347 PHE 348 0.0002

PHE 348 TRP 349 0.0002

TRP 349 GLU 350 0.0002

GLU 350 GLN 351 0.0004

GLN 351 ARG 352 0.0001

ARG 352 PHE 353 0.0001

PHE 353 ARG 354 -0.0003

ARG 354 CYS 355 0.0003

CYS 355 SER 356 -0.0001

SER 356 PHE 357 -0.0004

PHE 357 ARG 358 -0.0002

ARG 358 GLN 359 0.0002

GLN 359 ARG 360 -0.0001

ARG 360 ASP 361 -0.0005

ASP 361 CYS 362 0.0000

CYS 362 ALA 363 0.0000

ALA 363 ALA 364 -0.0004

ALA 364 HIS 365 0.0003

HIS 365 SER 366 -0.0004

SER 366 LEU 367 0.0000

LEU 367 ARG 368 -0.0000

ARG 368 ALA 369 0.0001

ALA 369 VAL 370 -0.0006

VAL 370 PRO 371 0.0003

PRO 371 PHE 372 -0.0001

PHE 372 GLU 373 0.0001

GLU 373 GLN 374 -0.0002

GLN 374 GLU 375 -0.0001

GLU 375 SER 376 0.0005

SER 376 LYS 377 -0.0001

LYS 377 ILE 378 0.0000

ILE 378 MET 379 0.0000

MET 379 PHE 380 0.0000

PHE 380 VAL 381 0.0003

VAL 381 VAL 382 -0.0002

VAL 382 ASN 383 0.0004

ASN 383 ALA 384 0.0005

ALA 384 VAL 385 -0.0002

VAL 385 TYR 386 -0.0000

TYR 386 ALA 387 -0.0002

ALA 387 MET 388 0.0003

MET 388 ALA 389 -0.0001

ALA 389 HIS 390 0.0000

HIS 390 ALA 391 -0.0000

ALA 391 LEU 392 -0.0003

LEU 392 HIS 393 0.0003

HIS 393 ASN 394 0.0001

ASN 394 MET 395 0.0002

MET 395 HIS 396 -0.0007

HIS 396 ARG 397 -0.0002

ARG 397 ALA 398 -0.0004

ALA 398 LEU 399 0.0001

LEU 399 CYS 400 0.0002

CYS 400 PRO 401 0.0001

PRO 401 ASN 402 -0.0000

ASN 402 THR 403 -0.0003

THR 403 THR 404 0.0000

THR 404 ARG 405 0.0006

ARG 405 LEU 406 -0.0002

LEU 406 CYS 407 -0.0004

CYS 407 ASP 408 0.0004

ASP 408 ALA 409 -0.0003

ALA 409 MET 410 -0.0000

MET 410 ARG 411 0.0005

ARG 411 PRO 412 0.0001

PRO 412 VAL 413 0.0001

VAL 413 ASN 414 -0.0001

ASN 414 GLY 415 -0.0001

GLY 415 ARG 416 0.0002

ARG 416 ARG 417 -0.0000

ARG 417 LEU 418 0.0001

LEU 418 TYR 419 -0.0002

TYR 419 LYS 420 -0.0002

LYS 420 ASP 421 -0.0003

ASP 421 PHE 422 -0.0005

PHE 422 VAL 423 -0.0002

VAL 423 LEU 424 -0.0003

LEU 424 ASN 425 0.0004

ASN 425 VAL 426 0.0002

VAL 426 LYS 427 -0.0002

LYS 427 PHE 428 -0.0001

PHE 428 ASP 429 0.0002

ASP 429 ALA 430 -0.0000

ALA 430 PRO 431 -0.0002

PRO 431 PHE 432 -0.0003

PHE 432 ARG 433 -0.0003

ARG 433 PRO 434 -0.0000

PRO 434 ALA 435 -0.0008

ALA 435 ASP 436 0.0002

ASP 436 THR 437 -0.0002

THR 437 HIS 438 -0.0004

HIS 438 ASN 439 -0.0001

ASN 439 GLU 440 0.0005

GLU 440 VAL 441 -0.0001

VAL 441 ARG 442 0.0001

ARG 442 PHE 443 0.0001

PHE 443 ASP 444 -0.0002

ASP 444 ARG 445 0.0002

ARG 445 PHE 446 0.0001

PHE 446 GLY 447 -0.0001

GLY 447 ASP 448 0.0004

ASP 448 GLY 449 -0.0002

GLY 449 ILE 450 0.0002

ILE 450 GLY 451 -0.0001

GLY 451 ARG 452 -0.0002

ARG 452 TYR 453 0.0002

TYR 453 ASN 454 0.0001

ASN 454 ILE 455 -0.0002

ILE 455 PHE 456 0.0001

PHE 456 THR 457 -0.0001

THR 457 TYR 458 0.0002

TYR 458 LEU 459 0.0000

LEU 459 ARG 460 -0.0002

ARG 460 ALA 461 0.0005

ALA 461 GLY 462 -0.0001

GLY 462 SER 463 0.0002

SER 463 GLY 464 -0.0003

GLY 464 ARG 465 -0.0003

ARG 465 TYR 466 0.0001

TYR 466 ARG 467 0.0001

ARG 467 TYR 468 -0.0002

TYR 468 GLN 469 0.0000

GLN 469 LYS 470 -0.0001

LYS 470 VAL 471 0.0003

VAL 471 GLY 472 -0.0002

GLY 472 TYR 473 0.0003

TYR 473 TRP 474 -0.0003

TRP 474 ALA 475 -0.0002

ALA 475 GLU 476 0.0003

GLU 476 GLY 477 0.0001

GLY 477 LEU 478 -0.0001

LEU 478 THR 479 0.0003

THR 479 LEU 480 -0.0000

LEU 480 ASP 481 0.0000

ASP 481 THR 482 0.0002

THR 482 SER 483 0.0002

SER 483 LEU 484 -0.0001

LEU 484 ILE 485 -0.0001

ILE 485 PRO 486 -0.0002

PRO 486 TRP 487 0.0044

TRP 487 ALA 488 -0.0000

ALA 488 SER 489 0.0003

SER 489 PRO 490 0.0002

PRO 490 SER 491 -0.0000

SER 491 ALA 492 0.0002

ALA 492 GLY 493 -0.0003

GLY 493 PRO 494 0.0002

PRO 494 LEU 495 -0.0001

LEU 495 PRO 496 0.0001

PRO 496 ALA 497 0.0001

ALA 497 SER 498 0.0000

SER 498 ARG 499 -0.0003

ARG 499 CYS 500 0.0018

CYS 500 SER 501 0.0000

SER 501 GLU 502 0.0002

GLU 502 PRO 503 0.0002

PRO 503 CYS 504 -0.0001

CYS 504 LEU 505 0.0001

LEU 505 GLN 506 -0.0004

GLN 506 ASN 507 0.0002

ASN 507 GLU 508 -0.0002

GLU 508 VAL 509 0.0002

VAL 509 LYS 510 -0.0003

LYS 510 SER 511 0.0002

SER 511 VAL 512 0.0002

VAL 512 GLN 513 -0.0339

GLN 513 PRO 514 0.0002

PRO 514 GLY 515 0.0001

GLY 515 GLU 516 -0.0000

GLU 516 VAL 517 -0.0004

VAL 517 CYS 518 -0.0002

CYS 518 CYS 519 -0.0000

CYS 519 TRP 520 -0.0002

TRP 520 LEU 521 0.0002

LEU 521 CYS 522 -0.0001

CYS 522 ILE 523 -0.0003

ILE 523 PRO 524 0.0002

PRO 524 CYS 525 -0.0001

CYS 525 GLN 526 -0.1492

GLN 526 PRO 527 -0.0003

PRO 527 TYR 528 0.0000

TYR 528 GLU 529 -0.0001

GLU 529 TYR 530 0.0002

TYR 530 ARG 531 -0.0001

ARG 531 LEU 532 0.0001

LEU 532 ASP 533 0.0001

ASP 533 GLU 534 0.0001

GLU 534 PHE 535 0.0001

PHE 535 THR 536 0.0000

THR 536 CYS 537 0.0004

CYS 537 ALA 538 -0.0004

ALA 538 ASP 539 -0.0260

ASP 539 CYS 540 0.0002

CYS 540 GLY 541 0.0001

GLY 541 LEU 542 -0.0004

LEU 542 GLY 543 0.0000

GLY 543 TYR 544 -0.0004

TYR 544 TRP 545 0.0001

TRP 545 PRO 546 0.0000

PRO 546 ASN 547 0.0002

ASN 547 ALA 548 -0.0001

ALA 548 SER 549 0.0002

SER 549 LEU 550 0.0001

LEU 550 THR 551 -0.0003

THR 551 GLY 552 -0.0429

GLY 552 CYS 553 -0.0000

CYS 553 PHE 554 -0.0002

PHE 554 GLU 555 -0.0003

GLU 555 LEU 556 0.0002

LEU 556 PRO 557 -0.0003

PRO 557 GLN 558 0.0001

GLN 558 GLU 559 -0.0002

GLU 559 TYR 560 -0.0000

TYR 560 ILE 561 0.0001

ILE 561 ARG 562 0.0001

ARG 562 TRP 563 0.0001

TRP 563 GLY 564 -0.0000

GLY 564 ASP 565 -0.0025

ASP 565 ALA 566 0.0002

ALA 566 TRP 567 0.0002

TRP 567 ALA 568 -0.0001

ALA 568 VAL 569 0.0001

VAL 569 GLY 570 -0.0000

GLY 570 PRO 571 0.0003

PRO 571 VAL 572 0.0001

VAL 572 THR 573 0.0002

THR 573 ILE 574 -0.0002

ILE 574 ALA 575 0.0001

ALA 575 CYS 576 0.0002

CYS 576 LEU 577 -0.0001

LEU 577 GLY 578 -0.0093

GLY 578 ALA 579 -0.0000

ALA 579 LEU 580 -0.0001

LEU 580 ALA 581 0.0001

ALA 581 THR 582 -0.0004

THR 582 LEU 583 -0.0003

LEU 583 PHE 584 -0.0000

PHE 584 VAL 585 -0.0003

VAL 585 LEU 586 0.0003

LEU 586 GLY 587 0.0004

GLY 587 VAL 588 -0.0002

VAL 588 PHE 589 -0.0003

PHE 589 VAL 590 0.0000

VAL 590 ARG 591 0.0082

ARG 591 HIS 592 0.0000

HIS 592 ASN 593 0.0001

ASN 593 ALA 594 -0.0002

ALA 594 THR 595 0.0000

THR 595 PRO 596 0.0002

PRO 596 VAL 597 -0.0001

VAL 597 VAL 598 0.0000

VAL 598 LYS 599 0.0001

LYS 599 ALA 600 0.0002

ALA 600 ALA 601 -0.0003

ALA 601 GLY 602 0.0002

GLY 602 ARG 603 0.0000

ARG 603 GLU 604 0.0120

GLU 604 LEU 605 -0.0001

LEU 605 CYS 606 0.0001

CYS 606 TYR 607 0.0001

TYR 607 ILE 608 -0.0001

ILE 608 LEU 609 0.0001

LEU 609 LEU 610 -0.0003

LEU 610 GLY 611 -0.0001

GLY 611 GLY 612 0.0000

GLY 612 VAL 613 0.0001

VAL 613 PHE 614 -0.0000

PHE 614 LEU 615 0.0003

LEU 615 CYS 616 0.0000

CYS 616 TYR 617 -0.0085

TYR 617 CYS 618 0.0000

CYS 618 MET 619 -0.0001

MET 619 THR 620 -0.0002

THR 620 PHE 621 0.0001

PHE 621 ILE 622 0.0004

ILE 622 PHE 623 -0.0001

PHE 623 ILE 624 -0.0002

ILE 624 ALA 625 -0.0001

ALA 625 LYS 626 0.0000

LYS 626 PRO 627 0.0001

PRO 627 SER 628 -0.0003

SER 628 THR 629 -0.0002

THR 629 ALA 630 -0.0140

ALA 630 VAL 631 -0.0002

VAL 631 CYS 632 -0.0002

CYS 632 THR 633 0.0004

THR 633 LEU 634 0.0004

LEU 634 ARG 635 0.0004

ARG 635 ARG 636 0.0003

ARG 636 LEU 637 -0.0005

LEU 637 GLY 638 0.0001

GLY 638 LEU 639 -0.0000

LEU 639 GLY 640 -0.0002

GLY 640 THR 641 -0.0001

THR 641 ALA 642 -0.0001

ALA 642 PHE 643 -0.0121

PHE 643 SER 644 0.0001

SER 644 VAL 645 0.0001

VAL 645 CYS 646 0.0003

CYS 646 TYR 647 0.0002

TYR 647 SER 648 0.0002

SER 648 ALA 649 0.0000

ALA 649 LEU 650 0.0002

LEU 650 LEU 651 0.0000

LEU 651 THR 652 0.0002

THR 652 LYS 653 0.0003

LYS 653 THR 654 -0.0001

THR 654 ASN 655 -0.0002

ASN 655 ARG 656 -0.0032

ARG 656 ILE 657 0.0000

ILE 657 ALA 658 0.0002

ALA 658 ARG 659 0.0003

ARG 659 ILE 660 -0.0001

ILE 660 PHE 661 0.0002

PHE 661 GLY 662 -0.0002

GLY 662 GLY 663 -0.0002

GLY 663 ALA 664 0.0002

ALA 664 ARG 665 0.0003

ARG 665 GLU 666 -0.0002

GLU 666 GLY 667 0.0001

GLY 667 ALA 668 -0.0000

ALA 668 GLN 669 0.0090

GLN 669 ARG 670 0.0002

ARG 670 PRO 671 -0.0002

PRO 671 ARG 672 -0.0002

ARG 672 PHE 673 0.0003

PHE 673 ILE 674 -0.0003

ILE 674 SER 675 0.0002

SER 675 PRO 676 0.0002

PRO 676 ALA 677 0.0002

ALA 677 SER 678 -0.0001

SER 678 GLN 679 0.0003

GLN 679 VAL 680 -0.0002

VAL 680 ALA 681 -0.0000

ALA 681 ILE 682 0.0110

ILE 682 CYS 683 0.0002

CYS 683 LEU 684 0.0001

LEU 684 ALA 685 0.0001

ALA 685 LEU 686 -0.0002

LEU 686 ILE 687 0.0001

ILE 687 SER 688 -0.0000

SER 688 GLY 689 -0.0001

GLY 689 GLN 690 0.0001

GLN 690 LEU 691 0.0002

LEU 691 LEU 692 0.0000

LEU 692 ILE 693 -0.0004

ILE 693 VAL 694 0.0001

VAL 694 VAL 695 0.0053

VAL 695 ALA 696 -0.0002

ALA 696 TRP 697 -0.0003

TRP 697 LEU 698 -0.0002

LEU 698 VAL 699 0.0005

VAL 699 VAL 700 0.0002

VAL 700 GLU 701 -0.0002

GLU 701 ALA 702 0.0003

ALA 702 PRO 703 -0.0004

PRO 703 GLY 704 0.0001

GLY 704 THR 705 -0.0002

THR 705 GLY 706 -0.0002

GLY 706 LYS 707 -0.0003

LYS 707 GLU 708 -0.0000

GLU 708 THR 709 0.0005

THR 709 ALA 710 -0.0000

ALA 710 PRO 711 0.0004

PRO 711 GLU 712 -0.0005

GLU 712 ARG 713 -0.0000

ARG 713 ARG 714 0.0001

ARG 714 GLU 715 -0.0000

GLU 715 VAL 716 0.0001

VAL 716 VAL 717 0.0000

VAL 717 THR 718 0.0000

THR 718 LEU 719 0.0003

LEU 719 ARG 720 -0.0002

ARG 720 CYS 721 -0.0353

CYS 721 ASN 722 0.0001

ASN 722 HIS 723 -0.0000

HIS 723 ARG 724 0.0002

ARG 724 ASP 725 0.0001

ASP 725 ALA 726 0.0002

ALA 726 SER 727 -0.0006

SER 727 MET 728 -0.0003

MET 728 LEU 729 0.0001

LEU 729 GLY 730 -0.0001

GLY 730 SER 731 -0.0000

SER 731 LEU 732 0.0003

LEU 732 ALA 733 0.0001

ALA 733 TYR 734 0.0186

TYR 734 ASN 735 -0.0000

ASN 735 VAL 736 0.0002

VAL 736 LEU 737 0.0000

LEU 737 LEU 738 0.0003

LEU 738 ILE 739 -0.0003

ILE 739 ALA 740 -0.0001

ALA 740 LEU 741 -0.0000

LEU 741 CYS 742 -0.0001

CYS 742 THR 743 0.0001

THR 743 LEU 744 0.0005

LEU 744 TYR 745 0.0002

TYR 745 ALA 746 0.0006

ALA 746 PHE 747 -0.0039

PHE 747 LYS 748 -0.0001

LYS 748 THR 749 0.0001

THR 749 ARG 750 -0.0000

ARG 750 LYS 751 -0.0003

LYS 751 CYS 752 0.0005

CYS 752 PRO 753 -0.0002

PRO 753 GLU 754 0.0002

GLU 754 ASN 755 -0.0002

ASN 755 PHE 756 -0.0000

PHE 756 ASN 757 -0.0003

ASN 757 GLU 758 -0.0005

GLU 758 ALA 759 0.0000

ALA 759 LYS 760 -0.0705

LYS 760 PHE 761 0.0001

PHE 761 ILE 762 0.0001

ILE 762 GLY 763 -0.0000

GLY 763 PHE 764 -0.0002

PHE 764 THR 765 -0.0000

THR 765 MET 766 0.0003

MET 766 TYR 767 0.0002

TYR 767 THR 768 0.0002

THR 768 THR 769 0.0001

THR 769 CYS 770 0.0001

CYS 770 ILE 771 -0.0003

ILE 771 ILE 772 -0.0002

ILE 772 TRP 773 -0.0092

TRP 773 LEU 774 -0.0001

LEU 774 ALA 775 -0.0004

ALA 775 PHE 776 0.0001

PHE 776 LEU 777 0.0002

LEU 777 PRO 778 -0.0002

PRO 778 ILE 779 -0.0003

ILE 779 PHE 780 -0.0004

PHE 780 TYR 781 -0.0001

TYR 781 VAL 782 -0.0001

VAL 782 THR 783 0.0002

THR 783 SER 784 0.0002

SER 784 SER 785 0.0005

SER 785 ASP 786 -0.0000

ASP 786 TYR 787 -0.0001

TYR 787 ARG 788 -0.0000

ARG 788 VAL 789 -0.0004

VAL 789 GLN 790 0.0002

GLN 790 THR 791 0.0002

THR 791 THR 792 0.0000

THR 792 THR 793 -0.0003

THR 793 MET 794 -0.0002

MET 794 CYS 795 -0.0001

CYS 795 VAL 796 0.0001

VAL 796 SER 797 -0.0000

SER 797 VAL 798 -0.0003

VAL 798 SER 799 -0.0078

SER 799 LEU 800 0.0004

LEU 800 SER 801 0.0002

SER 801 GLY 802 -0.0000

GLY 802 SER 803 -0.0004

SER 803 VAL 804 0.0002

VAL 804 VAL 805 -0.0001

VAL 805 LEU 806 -0.0001

LEU 806 GLY 807 -0.0004

GLY 807 CYS 808 0.0001

CYS 808 LEU 809 0.0002

LEU 809 PHE 810 -0.0004

PHE 810 ALA 811 -0.0004

ALA 811 PRO 812 -0.0221

PRO 812 LYS 813 -0.0000

LYS 813 LEU 814 0.0002

LEU 814 HIS 815 0.0001

HIS 815 ILE 816 0.0005

ILE 816 LYS 23 -0.0225

LYS 23 LYS 24 0.0000

LYS 24 VAL 25 -0.0000

VAL 25 LEU 26 0.0003

LEU 26 THR 27 -0.0004

THR 27 LEU 28 0.0001

LEU 28 GLU 29 0.0005

GLU 29 GLY 30 -0.0001

GLY 30 ASP 31 -0.0001

ASP 31 LEU 32 -0.0001

LEU 32 VAL 33 0.0003

VAL 33 LEU 34 -0.0002

LEU 34 GLY 35 -0.0003

GLY 35 GLY 36 -0.0009

GLY 36 LEU 37 0.0001

LEU 37 PHE 38 -0.0001

PHE 38 PRO 39 -0.0002

PRO 39 VAL 40 0.0000

VAL 40 HIS 41 -0.0000

HIS 41 GLN 42 -0.0001

GLN 42 LYS 43 0.0001

LYS 43 GLY 44 -0.0000

GLY 44 GLY 45 -0.0003

GLY 45 PRO 46 0.0001

PRO 46 ALA 47 -0.0003

ALA 47 GLU 48 0.0003

GLU 48 ASP 49 0.0021

ASP 49 CYS 50 -0.0003

CYS 50 GLY 51 0.0001

GLY 51 PRO 52 -0.0002

PRO 52 VAL 53 -0.0003

VAL 53 ASN 54 0.0001

ASN 54 GLU 55 -0.0001

GLU 55 HIS 56 -0.0000

HIS 56 ARG 57 -0.0002

ARG 57 GLY 58 -0.0004

GLY 58 ILE 59 0.0001

ILE 59 GLN 60 -0.0000

GLN 60 ARG 61 -0.0003

ARG 61 LEU 62 -0.0031

LEU 62 GLU 63 0.0003

GLU 63 ALA 64 -0.0000

ALA 64 MET 65 0.0000

MET 65 LEU 66 0.0001

LEU 66 PHE 67 0.0001

PHE 67 ALA 68 -0.0001

ALA 68 LEU 69 0.0002

LEU 69 ASP 70 -0.0000

ASP 70 ARG 71 0.0002

ARG 71 ILE 72 0.0001

ILE 72 ASN 73 0.0001

ASN 73 ARG 74 -0.0002

ARG 74 ASP 75 0.0016

ASP 75 PRO 76 0.0003

PRO 76 HIS 77 -0.0002

HIS 77 LEU 78 0.0000

LEU 78 LEU 79 0.0001

LEU 79 PRO 80 -0.0000

PRO 80 GLY 81 0.0002

GLY 81 VAL 82 -0.0001

VAL 82 ARG 83 0.0001

ARG 83 LEU 84 -0.0002

LEU 84 GLY 85 0.0001

GLY 85 ALA 86 0.0002

ALA 86 HIS 87 -0.0003

HIS 87 ILE 88 0.0000

ILE 88 LEU 89 -0.0001

LEU 89 ASP 90 0.0001

ASP 90 SER 91 -0.0001

SER 91 CYS 92 -0.0000

CYS 92 SER 93 -0.0003

SER 93 LYS 94 -0.0000

LYS 94 ASP 95 0.0002

ASP 95 THR 96 0.0003

THR 96 HIS 97 0.0000

HIS 97 ALA 98 0.0001

ALA 98 LEU 99 -0.0001

LEU 99 GLU 100 0.0004

GLU 100 GLN 101 -0.0006

GLN 101 ALA 102 -0.0002

ALA 102 LEU 103 -0.0001

LEU 103 ASP 104 0.0001

ASP 104 PHE 105 -0.0001

PHE 105 VAL 106 0.0003

VAL 106 ARG 107 0.0000

ARG 107 ALA 108 0.0003

ALA 108 SER 109 0.0001

SER 109 LEU 110 0.0002

LEU 110 THR 134 0.0018

THR 134 ALA 135 0.0001

ALA 135 ILE 136 -0.0001

ILE 136 THR 137 -0.0001

THR 137 GLY 138 0.0002

GLY 138 VAL 139 -0.0001

VAL 139 ILE 140 0.0002

ILE 140 GLY 141 0.0001

GLY 141 GLY 142 -0.0002

GLY 142 SER 143 0.0003

SER 143 TYR 144 -0.0003

TYR 144 SER 145 0.0000

SER 145 ASP 146 0.0002

ASP 146 VAL 147 -0.0019

VAL 147 SER 148 0.0000

SER 148 ILE 149 -0.0002

ILE 149 GLN 150 -0.0002

GLN 150 VAL 151 0.0001

VAL 151 ALA 152 0.0001

ALA 152 ASN 153 -0.0003

ASN 153 LEU 154 -0.0004

LEU 154 LEU 155 0.0000

LEU 155 ARG 156 -0.0001

ARG 156 LEU 157 0.0001

LEU 157 PHE 158 0.0002

PHE 158 GLN 159 -0.0004

GLN 159 ILE 160 0.0019

ILE 160 PRO 161 0.0001

PRO 161 GLN 162 -0.0000

GLN 162 ILE 163 -0.0004

ILE 163 SER 164 0.0002

SER 164 TYR 165 -0.0002

TYR 165 ALA 166 0.0003

ALA 166 SER 167 -0.0002

SER 167 THR 168 0.0000

THR 168 SER 169 -0.0000

SER 169 ALA 170 -0.0003

ALA 170 LYS 171 -0.0001

LYS 171 LEU 172 -0.0001

LEU 172 SER 173 0.0008

SER 173 ASP 174 0.0001

ASP 174 LYS 175 0.0003

LYS 175 SER 176 -0.0000

SER 176 ARG 177 -0.0000

ARG 177 TYR 178 -0.0000

TYR 178 ASP 179 -0.0004

ASP 179 TYR 180 -0.0001

TYR 180 PHE 181 0.0002

PHE 181 ALA 182 0.0002

ALA 182 ARG 183 0.0003

ARG 183 THR 184 -0.0000

THR 184 VAL 185 0.0000

VAL 185 PRO 186 -0.0079

PRO 186 PRO 187 -0.0003

PRO 187 ASP 188 0.0002

ASP 188 PHE 189 0.0000

PHE 189 PHE 190 0.0003

PHE 190 GLN 191 -0.0002

GLN 191 ALA 192 -0.0001

ALA 192 LYS 193 -0.0003

LYS 193 ALA 194 0.0001

ALA 194 MET 195 0.0002

MET 195 ALA 196 0.0001

ALA 196 GLU 197 -0.0001

GLU 197 ILE 198 -0.0002

ILE 198 LEU 199 -0.0107

LEU 199 ARG 200 0.0002

ARG 200 PHE 201 0.0003

PHE 201 PHE 202 -0.0002

PHE 202 ASN 203 0.0003

ASN 203 TRP 204 -0.0003

TRP 204 THR 205 -0.0003

THR 205 TYR 206 0.0002

TYR 206 VAL 207 -0.0001

VAL 207 SER 208 -0.0002

SER 208 THR 209 0.0002

THR 209 VAL 210 0.0002

VAL 210 ALA 211 -0.0002

ALA 211 SER 212 -0.0097

SER 212 GLU 213 0.0000

GLU 213 GLY 214 0.0001

GLY 214 ASP 215 -0.0000

ASP 215 TYR 216 -0.0001

TYR 216 GLY 217 0.0003

GLY 217 GLU 218 -0.0001

GLU 218 THR 219 0.0001

THR 219 GLY 220 0.0002

GLY 220 ILE 221 0.0002

ILE 221 GLU 222 -0.0001

GLU 222 ALA 223 0.0003

ALA 223 PHE 224 -0.0004

PHE 224 GLU 225 -0.0090

GLU 225 LEU 226 -0.0000

LEU 226 GLU 227 0.0003

GLU 227 ALA 228 0.0003

ALA 228 ARG 229 0.0003

ARG 229 ALA 230 -0.0003

ALA 230 ARG 231 -0.0002

ARG 231 ASN 232 -0.0002

ASN 232 ILE 233 -0.0004

ILE 233 CYS 234 -0.0001

CYS 234 VAL 235 -0.0001

VAL 235 ALA 236 0.0001

ALA 236 THR 237 0.0003

THR 237 SER 238 -0.0084

SER 238 GLU 239 -0.0001

GLU 239 LYS 240 0.0002

LYS 240 VAL 241 -0.0000

VAL 241 GLY 242 -0.0000

GLY 242 ARG 243 -0.0001

ARG 243 ALA 244 0.0001

ALA 244 MET 245 -0.0001

MET 245 SER 246 -0.0001

SER 246 ARG 247 -0.0000

ARG 247 ALA 248 0.0001

ALA 248 ALA 249 0.0001

ALA 249 PHE 250 0.0005

PHE 250 GLU 251 0.0005

GLU 251 GLY 252 -0.0004

GLY 252 VAL 253 -0.0000

VAL 253 VAL 254 -0.0001

VAL 254 ARG 255 -0.0003

ARG 255 ALA 256 0.0002

ALA 256 LEU 257 -0.0004

LEU 257 LEU 258 0.0004

LEU 258 GLN 259 -0.0004

GLN 259 LYS 260 -0.0002

LYS 260 PRO 261 0.0001

PRO 261 SER 262 0.0001

SER 262 ALA 263 0.0003

ALA 263 ARG 264 0.0016

ARG 264 VAL 265 0.0001

VAL 265 ALA 266 -0.0001

ALA 266 VAL 267 0.0002

VAL 267 LEU 268 -0.0001

LEU 268 PHE 269 0.0002

PHE 269 THR 270 -0.0001

THR 270 ARG 271 -0.0001

ARG 271 SER 272 0.0004

SER 272 GLU 273 -0.0003

GLU 273 ASP 274 0.0001

ASP 274 ALA 275 -0.0000

ALA 275 ARG 276 -0.0002

ARG 276 GLU 277 -0.0003

GLU 277 LEU 278 0.0003

LEU 278 LEU 279 -0.0001

LEU 279 ALA 280 0.0001

ALA 280 ALA 281 0.0001

ALA 281 SER 282 0.0004

SER 282 GLN 283 -0.0000

GLN 283 ARG 284 0.0001

ARG 284 LEU 285 0.0002

LEU 285 ASN 286 -0.0002

ASN 286 ALA 287 -0.0004

ALA 287 SER 288 0.0003

SER 288 PHE 289 -0.0003

PHE 289 THR 290 -0.0012

THR 290 TRP 291 0.0003

TRP 291 VAL 292 -0.0001

VAL 292 ALA 293 0.0001

ALA 293 SER 294 -0.0000

SER 294 ASP 295 0.0003

ASP 295 GLY 296 0.0001

GLY 296 TRP 297 -0.0002

TRP 297 GLY 298 0.0003

GLY 298 ALA 299 0.0001

ALA 299 LEU 300 -0.0000

LEU 300 GLU 301 0.0004

GLU 301 SER 302 -0.0002

SER 302 VAL 303 0.0006

VAL 303 VAL 304 -0.0000

VAL 304 ALA 305 0.0002

ALA 305 GLY 306 -0.0000

GLY 306 SER 307 0.0000

SER 307 GLU 308 -0.0002

GLU 308 GLY 309 -0.0001

GLY 309 ALA 310 -0.0003

ALA 310 ALA 311 -0.0001

ALA 311 GLU 312 -0.0002

GLU 312 GLY 313 -0.0002

GLY 313 ALA 314 -0.0003

ALA 314 ILE 315 0.0001

ILE 315 THR 316 -0.0053

THR 316 ILE 317 -0.0001

ILE 317 GLU 318 0.0000

GLU 318 LEU 319 -0.0002

LEU 319 ALA 320 0.0002

ALA 320 SER 321 0.0000

SER 321 TYR 322 -0.0000

TYR 322 PRO 323 0.0004

PRO 323 ILE 324 -0.0002

ILE 324 SER 325 0.0001

SER 325 ASP 326 -0.0005

ASP 326 PHE 327 -0.0001

PHE 327 ALA 328 0.0000

ALA 328 SER 329 -0.0052

SER 329 TYR 330 -0.0001

TYR 330 PHE 331 -0.0001

PHE 331 GLN 332 -0.0002

GLN 332 SER 333 -0.0001

SER 333 LEU 334 -0.0001

LEU 334 ASP 335 -0.0001

ASP 335 PRO 336 -0.0000

PRO 336 TRP 337 0.0002

TRP 337 ASN 338 0.0001

ASN 338 ASN 339 -0.0003

ASN 339 SER 340 0.0005

SER 340 ARG 341 -0.0000

ARG 341 ASN 342 -0.0007

ASN 342 PRO 343 0.0000

PRO 343 TRP 344 -0.0000

TRP 344 PHE 345 -0.0002

PHE 345 ARG 346 -0.0000

ARG 346 GLU 347 -0.0002

GLU 347 PHE 348 -0.0000

PHE 348 TRP 349 0.0003

TRP 349 GLU 350 0.0001

GLU 350 GLN 351 0.0001

GLN 351 ARG 352 -0.0003

ARG 352 PHE 353 0.0003

PHE 353 ARG 354 0.0005

ARG 354 CYS 355 -0.0027

CYS 355 SER 356 0.0001

SER 356 PHE 357 0.0004

PHE 357 ARG 358 -0.0003

ARG 358 GLN 359 0.0003

GLN 359 ARG 360 -0.0001

ARG 360 ASP 361 -0.0002

ASP 361 CYS 362 -0.0003

CYS 362 ALA 363 -0.0003

ALA 363 ALA 364 -0.0002

ALA 364 HIS 365 -0.0002

HIS 365 SER 366 0.0001

SER 366 LEU 367 -0.0004

LEU 367 ARG 368 0.0011

ARG 368 ALA 369 0.0004

ALA 369 VAL 370 0.0000

VAL 370 PRO 371 -0.0003

PRO 371 PHE 372 0.0002

PHE 372 GLU 373 0.0004

GLU 373 GLN 374 -0.0004

GLN 374 GLU 375 -0.0001

GLU 375 SER 376 0.0001

SER 376 LYS 377 -0.0001

LYS 377 ILE 378 -0.0000

ILE 378 MET 379 -0.0002

MET 379 PHE 380 -0.0001

PHE 380 VAL 381 -0.0036

VAL 381 VAL 382 -0.0005

VAL 382 ASN 383 0.0001

ASN 383 ALA 384 -0.0004

ALA 384 VAL 385 0.0003

VAL 385 TYR 386 0.0001

TYR 386 ALA 387 0.0002

ALA 387 MET 388 0.0001

MET 388 ALA 389 -0.0000

ALA 389 HIS 390 -0.0003

HIS 390 ALA 391 -0.0000

ALA 391 LEU 392 0.0002

LEU 392 HIS 393 0.0002

HIS 393 ASN 394 0.0001

ASN 394 MET 395 0.0004

MET 395 HIS 396 0.0003

HIS 396 ARG 397 -0.0000

ARG 397 ALA 398 0.0003

ALA 398 LEU 399 0.0002

LEU 399 CYS 400 0.0001

CYS 400 PRO 401 0.0003

PRO 401 ASN 402 0.0001

ASN 402 THR 403 0.0001

THR 403 THR 404 0.0001

THR 404 ARG 405 -0.0001

ARG 405 LEU 406 -0.0002

LEU 406 CYS 407 0.0002

CYS 407 ASP 408 0.0004

ASP 408 ALA 409 -0.0002

ALA 409 MET 410 -0.0001

MET 410 ARG 411 0.0001

ARG 411 PRO 412 0.0004

PRO 412 VAL 413 -0.0002

VAL 413 ASN 414 0.0002

ASN 414 GLY 415 -0.0002

GLY 415 ARG 416 0.0001

ARG 416 ARG 417 0.0002

ARG 417 LEU 418 -0.0004

LEU 418 TYR 419 -0.0000

TYR 419 LYS 420 -0.0002

LYS 420 ASP 421 -0.0000

ASP 421 PHE 422 -0.0004

PHE 422 VAL 423 0.0000

VAL 423 LEU 424 0.0002

LEU 424 ASN 425 -0.0002

ASN 425 VAL 426 0.0002

VAL 426 LYS 427 0.0002

LYS 427 PHE 428 0.0000

PHE 428 ASP 429 0.0001

ASP 429 ALA 430 -0.0003

ALA 430 PRO 431 -0.0000

PRO 431 PHE 432 0.0001

PHE 432 ARG 433 0.0012

ARG 433 PRO 434 -0.0002

PRO 434 ALA 435 0.0000

ALA 435 ASP 436 -0.0002

ASP 436 THR 437 0.0002

THR 437 HIS 438 -0.0001

HIS 438 ASN 439 0.0005

ASN 439 GLU 440 -0.0001

GLU 440 VAL 441 -0.0002

VAL 441 ARG 442 -0.0001

ARG 442 PHE 443 0.0003

PHE 443 ASP 444 0.0000

ASP 444 ARG 445 -0.0003

ARG 445 PHE 446 0.0006

PHE 446 GLY 447 -0.0002

GLY 447 ASP 448 -0.0003

ASP 448 GLY 449 -0.0001

GLY 449 ILE 450 0.0003

ILE 450 GLY 451 0.0002

GLY 451 ARG 452 0.0000

ARG 452 TYR 453 0.0001

TYR 453 ASN 454 -0.0001

ASN 454 ILE 455 0.0002

ILE 455 PHE 456 -0.0001

PHE 456 THR 457 0.0002

THR 457 TYR 458 -0.0003

TYR 458 LEU 459 0.0012

LEU 459 ARG 460 -0.0000

ARG 460 ALA 461 -0.0001

ALA 461 GLY 462 0.0000

GLY 462 SER 463 -0.0002

SER 463 GLY 464 0.0003

GLY 464 ARG 465 0.0001

ARG 465 TYR 466 -0.0000

TYR 466 ARG 467 -0.0001

ARG 467 TYR 468 0.0002

TYR 468 GLN 469 0.0003

GLN 469 LYS 470 -0.0004

LYS 470 VAL 471 0.0000

VAL 471 GLY 472 0.0018

GLY 472 TYR 473 -0.0001

TYR 473 TRP 474 0.0000

TRP 474 ALA 475 0.0001

ALA 475 GLU 476 0.0003

GLU 476 GLY 477 0.0001

GLY 477 LEU 478 -0.0003

LEU 478 THR 479 0.0002

THR 479 LEU 480 0.0000

LEU 480 ASP 481 -0.0001

ASP 481 THR 482 0.0001

THR 482 SER 483 0.0004

SER 483 LEU 484 -0.0003

LEU 484 ILE 485 -0.0036

ILE 485 PRO 486 -0.0002

PRO 486 TRP 487 -0.0004

TRP 487 ALA 488 -0.0001

ALA 488 SER 489 -0.0002

SER 489 PRO 490 -0.0000

PRO 490 SER 491 0.0004

SER 491 ALA 492 0.0001

ALA 492 GLY 493 0.0004

GLY 493 PRO 494 -0.0004

PRO 494 LEU 495 -0.0002

LEU 495 PRO 496 0.0001

PRO 496 ALA 497 0.0001

ALA 497 SER 498 0.0049

SER 498 ARG 499 -0.0001

ARG 499 CYS 500 0.0001

CYS 500 SER 501 0.0004

SER 501 GLU 502 0.0001

GLU 502 PRO 503 0.0001

PRO 503 CYS 504 0.0000

CYS 504 LEU 505 0.0001

LEU 505 GLN 506 -0.0001

GLN 506 ASN 507 -0.0005

ASN 507 GLU 508 0.0002

GLU 508 VAL 509 -0.0000

VAL 509 LYS 510 -0.0000

LYS 510 SER 511 -0.0037

SER 511 VAL 512 -0.0001

VAL 512 GLN 513 -0.0004

GLN 513 PRO 514 0.0001

PRO 514 GLY 515 -0.0001

GLY 515 GLU 516 -0.0001

GLU 516 VAL 517 -0.0001

VAL 517 CYS 518 0.0003

CYS 518 CYS 519 0.0001

CYS 519 TRP 520 -0.0001

TRP 520 LEU 521 -0.0000

LEU 521 CYS 522 0.0001

CYS 522 ILE 523 -0.0004

ILE 523 PRO 524 -0.0230

PRO 524 CYS 525 -0.0000

CYS 525 GLN 526 0.0000

GLN 526 PRO 527 -0.0002

PRO 527 TYR 528 -0.0002

TYR 528 GLU 529 -0.0001

GLU 529 TYR 530 0.0002

TYR 530 ARG 531 0.0004

ARG 531 LEU 532 -0.0004

LEU 532 ASP 533 -0.0001

ASP 533 GLU 534 0.0000

GLU 534 PHE 535 -0.0001

PHE 535 THR 536 -0.0002

THR 536 CYS 537 -0.0224

CYS 537 ALA 538 -0.0001

ALA 538 ASP 539 -0.0003

ASP 539 CYS 540 0.0001

CYS 540 GLY 541 -0.0002

GLY 541 LEU 542 -0.0000

LEU 542 GLY 543 0.0004

GLY 543 TYR 544 0.0002

TYR 544 TRP 545 -0.0001

TRP 545 PRO 546 -0.0002

PRO 546 ASN 547 -0.0001

ASN 547 ALA 548 -0.0001

ALA 548 SER 549 -0.0002

SER 549 LEU 550 0.0071

LEU 550 THR 551 0.0000

THR 551 GLY 552 -0.0001

GLY 552 CYS 553 0.0002

CYS 553 PHE 554 0.0001

PHE 554 GLU 555 -0.0002

GLU 555 LEU 556 0.0002

LEU 556 PRO 557 -0.0000

PRO 557 GLN 558 0.0001

GLN 558 GLU 559 0.0000

GLU 559 TYR 560 0.0002

TYR 560 ILE 561 0.0000

ILE 561 ARG 562 -0.0001

ARG 562 TRP 563 0.0117

TRP 563 GLY 564 -0.0004

GLY 564 ASP 565 0.0002

ASP 565 ALA 566 0.0001

ALA 566 TRP 567 -0.0006

TRP 567 ALA 568 -0.0003

ALA 568 VAL 569 0.0001

VAL 569 GLY 570 0.0003

GLY 570 PRO 571 0.0003

PRO 571 VAL 572 -0.0003

VAL 572 THR 573 -0.0002

THR 573 ILE 574 -0.0000

ILE 574 ALA 575 0.0002

ALA 575 CYS 576 0.0045

CYS 576 LEU 577 -0.0002

LEU 577 GLY 578 0.0001

GLY 578 ALA 579 -0.0005

ALA 579 LEU 580 -0.0000

LEU 580 ALA 581 -0.0000

ALA 581 THR 582 -0.0002

THR 582 LEU 583 -0.0004

LEU 583 PHE 584 0.0002

PHE 584 VAL 585 -0.0004

VAL 585 LEU 586 -0.0003

LEU 586 GLY 587 0.0003

GLY 587 VAL 588 -0.0002

VAL 588 PHE 589 0.0007

PHE 589 VAL 590 0.0001

VAL 590 ARG 591 0.0000

ARG 591 HIS 592 0.0001

HIS 592 ASN 593 0.0001

ASN 593 ALA 594 -0.0002

ALA 594 THR 595 -0.0002

THR 595 PRO 596 0.0001

PRO 596 VAL 597 -0.0002

VAL 597 VAL 598 0.0003

VAL 598 LYS 599 0.0004

LYS 599 ALA 600 0.0000

ALA 600 ALA 601 -0.0001

ALA 601 GLY 602 0.0005

GLY 602 ARG 603 -0.0002

ARG 603 GLU 604 0.0001

GLU 604 LEU 605 -0.0000

LEU 605 CYS 606 0.0000

CYS 606 TYR 607 -0.0002

TYR 607 ILE 608 -0.0000

ILE 608 LEU 609 0.0002

LEU 609 LEU 610 0.0000

LEU 610 GLY 611 -0.0001

GLY 611 GLY 612 0.0001

GLY 612 VAL 613 0.0004

VAL 613 PHE 614 0.0001

PHE 614 LEU 615 -0.0013

LEU 615 CYS 616 -0.0001

CYS 616 TYR 617 0.0002

TYR 617 CYS 618 -0.0004

CYS 618 MET 619 -0.0002

MET 619 THR 620 -0.0004

THR 620 PHE 621 -0.0001

PHE 621 ILE 622 -0.0003

ILE 622 PHE 623 -0.0002

PHE 623 ILE 624 0.0002

ILE 624 ALA 625 0.0000

ALA 625 LYS 626 0.0004

LYS 626 PRO 627 0.0000

PRO 627 SER 628 -0.0005

SER 628 THR 629 -0.0003

THR 629 ALA 630 -0.0000

ALA 630 VAL 631 -0.0001

VAL 631 CYS 632 0.0001

CYS 632 THR 633 -0.0002

THR 633 LEU 634 -0.0001

LEU 634 ARG 635 0.0002

ARG 635 ARG 636 -0.0000

ARG 636 LEU 637 0.0004

LEU 637 GLY 638 0.0001

GLY 638 LEU 639 -0.0001

LEU 639 GLY 640 0.0000

GLY 640 THR 641 -0.0022

THR 641 ALA 642 -0.0002

ALA 642 PHE 643 0.0001

PHE 643 SER 644 0.0001

SER 644 VAL 645 -0.0003

VAL 645 CYS 646 0.0001

CYS 646 TYR 647 -0.0000

TYR 647 SER 648 -0.0001

SER 648 ALA 649 -0.0004

ALA 649 LEU 650 0.0002

LEU 650 LEU 651 -0.0000

LEU 651 THR 652 0.0002

THR 652 LYS 653 -0.0004

LYS 653 THR 654 0.0059

THR 654 ASN 655 -0.0000

ASN 655 ARG 656 -0.0003

ARG 656 ILE 657 -0.0001

ILE 657 SER 675 0.0013

SER 675 PRO 676 0.0003

PRO 676 ALA 677 -0.0002

ALA 677 SER 678 -0.0001

SER 678 GLN 679 0.0001

GLN 679 VAL 680 -0.0000

VAL 680 ALA 681 0.0003

ALA 681 ILE 682 0.0001

ILE 682 CYS 683 -0.0000

CYS 683 LEU 684 0.0003

LEU 684 ALA 685 -0.0002

ALA 685 LEU 686 0.0001

LEU 686 ILE 687 -0.0002

ILE 687 SER 688 -0.0027

SER 688 GLY 689 -0.0002

GLY 689 GLN 690 -0.0003

GLN 690 LEU 691 -0.0000

LEU 691 LEU 692 -0.0002

LEU 692 ILE 693 0.0000

ILE 693 VAL 694 -0.0003

VAL 694 VAL 695 -0.0002

VAL 695 ALA 696 -0.0000

ALA 696 TRP 697 -0.0001

TRP 697 LEU 698 -0.0001

LEU 698 VAL 699 -0.0000

VAL 699 VAL 700 0.0000

VAL 700 GLU 701 0.0041

GLU 701 ALA 702 0.0003

ALA 702 PRO 703 -0.0000

PRO 703 GLY 704 -0.0002

GLY 704 THR 705 0.0001

THR 705 GLY 706 -0.0003

GLY 706 LYS 707 -0.0001

LYS 707 GLU 708 -0.0001

GLU 708 THR 709 -0.0002

THR 709 ALA 710 -0.0001

ALA 710 PRO 711 0.0004

PRO 711 GLU 712 -0.0002

GLU 712 ARG 713 -0.0001

ARG 713 ARG 714 0.0060

ARG 714 GLU 715 -0.0003

GLU 715 VAL 716 0.0002

VAL 716 VAL 717 -0.0001

VAL 717 THR 718 0.0001

THR 718 LEU 719 0.0000

LEU 719 ARG 720 0.0001

ARG 720 CYS 721 0.0001

CYS 721 ASN 722 -0.0000

ASN 722 HIS 723 -0.0001

HIS 723 ARG 724 -0.0000

ARG 724 ASP 725 0.0000

ASP 725 ALA 726 0.0001

ALA 726 SER 727 -0.0352

SER 727 MET 728 -0.0003

MET 728 LEU 729 0.0003

LEU 729 GLY 730 -0.0002

GLY 730 SER 731 0.0001

SER 731 LEU 732 -0.0001

LEU 732 ALA 733 0.0000

ALA 733 TYR 734 0.0004

TYR 734 ASN 735 -0.0000

ASN 735 VAL 736 0.0001

VAL 736 LEU 737 0.0001

LEU 737 LEU 738 0.0000

LEU 738 ILE 739 -0.0002

ILE 739 ALA 740 0.0027

ALA 740 LEU 741 -0.0000

LEU 741 CYS 742 -0.0003

CYS 742 THR 743 -0.0000

THR 743 LEU 744 0.0003

LEU 744 TYR 745 -0.0000

TYR 745 ALA 746 0.0002

ALA 746 PHE 747 0.0001

PHE 747 LYS 748 -0.0000

LYS 748 THR 749 0.0003

THR 749 ARG 750 -0.0002

ARG 750 LYS 751 -0.0001

LYS 751 CYS 752 0.0003

CYS 752 PRO 753 -0.0127

PRO 753 GLU 754 0.0003

GLU 754 ASN 755 -0.0002

ASN 755 PHE 756 -0.0001

PHE 756 ASN 757 -0.0004

ASN 757 GLU 758 -0.0002

GLU 758 ALA 759 0.0002

ALA 759 LYS 760 0.0001

LYS 760 PHE 761 -0.0001

PHE 761 ILE 762 0.0000

ILE 762 GLY 763 0.0001

GLY 763 PHE 764 -0.0001

PHE 764 THR 765 -0.0000

THR 765 MET 766 -0.0081

MET 766 TYR 767 0.0002

TYR 767 THR 768 0.0003

THR 768 THR 769 -0.0001

THR 769 CYS 770 0.0005

CYS 770 ILE 771 0.0000

ILE 771 ILE 772 -0.0002

ILE 772 TRP 773 -0.0002

TRP 773 LEU 774 -0.0005

LEU 774 ALA 775 0.0003

ALA 775 PHE 776 -0.0001

PHE 776 LEU 777 0.0000

LEU 777 PRO 778 -0.0002

PRO 778 ILE 779 0.0032

ILE 779 PHE 780 0.0002

PHE 780 TYR 781 0.0003

TYR 781 VAL 782 0.0002

VAL 782 THR 783 -0.0004

THR 783 SER 784 0.0004

SER 784 SER 785 0.0000

SER 785 ASP 786 0.0001

ASP 786 TYR 787 0.0004

TYR 787 ARG 788 -0.0002

ARG 788 VAL 789 0.0002

VAL 789 GLN 790 -0.0001

GLN 790 THR 791 -0.0004

THR 791 THR 792 -0.0073

THR 792 THR 793 0.0001

THR 793 MET 794 0.0000

MET 794 CYS 795 0.0003

CYS 795 VAL 796 0.0001

VAL 796 SER 797 0.0000

SER 797 VAL 798 -0.0001

VAL 798 SER 799 -0.0003

SER 799 LEU 800 -0.0000

LEU 800 SER 801 -0.0001

SER 801 GLY 802 -0.0003

GLY 802 SER 803 0.0003

SER 803 VAL 804 0.0001

VAL 804 VAL 805 0.0088

VAL 805 LEU 806 -0.0000

LEU 806 GLY 807 -0.0004

GLY 807 CYS 808 -0.0003

CYS 808 LEU 809 0.0001

LEU 809 PHE 810 -0.0003

PHE 810 ALA 811 0.0001

ALA 811 PRO 812 -0.0006

PRO 812 LYS 813 -0.0001

LYS 813 LEU 814 -0.0003

LEU 814 HIS 815 0.0005

HIS 815 ILE 816 -0.0000

ILE 816 ILE 817 -0.0002

ILE 817 SER 6 -0.0233

SER 6 ALA 7 -0.0000

ALA 7 GLU 8 -0.0002

GLU 8 ASP 9 -0.0001

ASP 9 LYS 10 -0.0000

LYS 10 ALA 11 0.0000

ALA 11 ALA 12 -0.0004

ALA 12 VAL 13 0.0002

VAL 13 GLU 14 0.0000

GLU 14 ARG 15 -0.0004

ARG 15 SER 16 0.0002

SER 16 LYS 17 -0.0002

LYS 17 MET 18 -0.0003

MET 18 ILE 19 -0.0020

ILE 19 ASP 20 0.0001

ASP 20 ARG 21 0.0002

ARG 21 ASN 22 -0.0000

ASN 22 LEU 23 -0.0000

LEU 23 ARG 24 -0.0003

ARG 24 GLU 25 -0.0001

GLU 25 ASP 26 -0.0005

ASP 26 GLY 27 -0.0002

GLY 27 GLU 28 0.0002

GLU 28 LYS 29 -0.0000

LYS 29 ALA 30 -0.0001

ALA 30 ALA 31 0.0003

ALA 31 ARG 32 -0.0063

ARG 32 GLU 33 0.0003

GLU 33 VAL 34 -0.0003

VAL 34 LYS 35 0.0001

LYS 35 LEU 36 -0.0001

LEU 36 LEU 37 0.0002

LEU 37 LEU 38 -0.0003

LEU 38 LEU 39 0.0004

LEU 39 GLY 40 -0.0004

GLY 40 ALA 41 0.0003

ALA 41 GLY 42 -0.0001

GLY 42 GLU 43 0.0001

GLU 43 SER 44 -0.0002

SER 44 GLY 45 0.0050

GLY 45 LYS 46 -0.0001

LYS 46 ASN 47 -0.0001

ASN 47 THR 48 0.0002

THR 48 ILE 49 0.0004

ILE 49 VAL 50 -0.0002

VAL 50 LYS 51 -0.0002

LYS 51 GLN 52 0.0000

GLN 52 MET 53 0.0002

MET 53 LYS 54 0.0001

LYS 54 ILE 55 0.0001

ILE 55 THR 182 -0.0006

THR 182 GLY 183 -0.0001

GLY 183 ILE 184 0.0002

ILE 184 VAL 185 0.0002

VAL 185 GLU 186 0.0000

GLU 186 THR 187 0.0001

THR 187 HIS 188 0.0002

HIS 188 PHE 189 -0.0005

PHE 189 THR 190 0.0001

THR 190 PHE 191 -0.0000

PHE 191 LYS 192 0.0001

LYS 192 ASP 193 -0.0003

ASP 193 LEU 194 -0.0000

LEU 194 HIS 195 0.0006

HIS 195 PHE 196 -0.0002

PHE 196 LYS 197 0.0001

LYS 197 MET 198 -0.0000

MET 198 PHE 199 0.0002

PHE 199 ASP 200 -0.0000

ASP 200 VAL 201 0.0001

VAL 201 GLY 202 -0.0001

GLY 202 ALA 203 0.0001

ALA 203 GLN 204 -0.0002

GLN 204 ARG 205 -0.0002

ARG 205 SER 206 0.0004

SER 206 GLU 207 -0.0002

GLU 207 ARG 208 0.0016

ARG 208 LYS 209 0.0001

LYS 209 LYS 210 0.0000

LYS 210 TRP 211 -0.0001

TRP 211 ILE 212 -0.0003

ILE 212 HIS 213 -0.0004

HIS 213 CYS 214 -0.0002

CYS 214 PHE 215 0.0000

PHE 215 GLU 216 -0.0000

GLU 216 GLY 217 0.0000

GLY 217 VAL 218 0.0004

VAL 218 THR 219 -0.0001

THR 219 ALA 220 0.0001

ALA 220 ILE 221 0.0010

ILE 221 ILE 222 0.0002

ILE 222 PHE 223 -0.0002

PHE 223 CYS 224 0.0003

CYS 224 VAL 225 -0.0001

VAL 225 ALA 226 -0.0002

ALA 226 LEU 227 0.0001

LEU 227 SER 228 0.0001

SER 228 ASP 229 -0.0005

ASP 229 TYR 230 0.0001

TYR 230 ASP 231 0.0002

ASP 231 LEU 232 -0.0002

LEU 232 VAL 233 0.0000

VAL 233 LEU 234 -0.0013

LEU 234 ALA 235 -0.0001

ALA 235 GLU 236 0.0002

GLU 236 ASP 237 0.0002

ASP 237 GLU 238 -0.0001

GLU 238 GLU 239 -0.0004

GLU 239 MET 240 0.0001

MET 240 ASN 241 0.0001

ASN 241 ARG 242 -0.0003

ARG 242 MET 243 0.0003

MET 243 HIS 244 -0.0002

HIS 244 ALA 245 0.0002

ALA 245 SER 246 -0.0001

SER 246 MET 247 -0.0111

MET 247 LYS 248 -0.0003

LYS 248 LEU 249 -0.0002

LEU 249 PHE 250 -0.0001

PHE 250 ASP 251 0.0001

ASP 251 SER 252 0.0002

SER 252 ILE 253 0.0003

ILE 253 CYS 254 -0.0002

CYS 254 ASN 255 -0.0002

ASN 255 ASN 256 -0.0000

ASN 256 LYS 257 -0.0002

LYS 257 TRP 258 -0.0001

TRP 258 PHE 259 0.0000

PHE 259 THR 260 -0.0114

THR 260 ASP 261 0.0002

ASP 261 THR 262 0.0001

THR 262 SER 263 -0.0001

SER 263 ILE 264 -0.0002

ILE 264 ILE 265 0.0002

ILE 265 LEU 266 0.0000

LEU 266 PHE 267 -0.0000

PHE 267 LEU 268 0.0000

LEU 268 ASN 269 0.0001

ASN 269 LYS 270 -0.0003

LYS 270 LYS 271 -0.0000

LYS 271 ASP 272 -0.0003

ASP 272 LEU 273 -0.0100

LEU 273 PHE 274 -0.0000

PHE 274 GLU 275 -0.0002

GLU 275 GLU 276 0.0002

GLU 276 LYS 277 0.0003

LYS 277 ILE 278 -0.0004

ILE 278 LYS 279 0.0003

LYS 279 LYS 280 -0.0000

LYS 280 SER 281 -0.0002

SER 281 PRO 282 -0.0000

PRO 282 LEU 283 -0.0002

LEU 283 THR 284 0.0005

THR 284 ILE 285 -0.0000

ILE 285 CYS 286 -0.0019

CYS 286 TYR 287 0.0000

TYR 287 PRO 288 -0.0000

PRO 288 GLU 289 -0.0002

GLU 289 TYR 290 0.0001

TYR 290 ALA 291 -0.0001

ALA 291 GLY 292 -0.0001

GLY 292 SER 293 0.0001

SER 293 ASN 294 0.0000

ASN 294 THR 295 -0.0001

THR 295 TYR 296 0.0003

TYR 296 GLU 297 0.0004

GLU 297 GLU 298 0.0001

GLU 298 ALA 299 -0.0005

ALA 299 ALA 300 0.0003

ALA 300 ALA 301 0.0000

ALA 301 TYR 302 -0.0002

TYR 302 ILE 303 0.0000

ILE 303 GLN 304 0.0001

GLN 304 CYS 305 0.0001

CYS 305 GLN 306 0.0001

GLN 306 PHE 307 -0.0000

PHE 307 GLU 308 0.0004

GLU 308 ASP 309 -0.0000

ASP 309 LEU 310 0.0001

LEU 310 ASN 311 0.0003

ASN 311 LYS 312 -0.0060

LYS 312 ARG 313 0.0001

ARG 313 LYS 314 0.0002

LYS 314 ASP 315 0.0003

ASP 315 THR 316 -0.0001

THR 316 LYS 317 0.0003

LYS 317 GLU 318 -0.0002

GLU 318 ILE 319 -0.0000

ILE 319 TYR 320 0.0000

TYR 320 THR 321 0.0002

THR 321 HIS 322 -0.0004

HIS 322 PHE 323 0.0004

PHE 323 THR 324 0.0000

THR 324 CYS 325 0.0096

CYS 325 SER 326 -0.0001

SER 326 THR 327 -0.0000

THR 327 ASP 328 0.0002

ASP 328 THR 329 0.0000

THR 329 LYS 330 -0.0002

LYS 330 ASN 331 0.0001

ASN 331 VAL 332 -0.0003

VAL 332 GLN 333 0.0000

GLN 333 PHE 334 -0.0004

PHE 334 VAL 335 0.0001

VAL 335 PHE 336 0.0002

PHE 336 ASP 337 -0.0003

ASP 337 ALA 338 0.0120

ALA 338 VAL 339 -0.0003

VAL 339 THR 340 -0.0000

THR 340 ASP 341 0.0004

ASP 341 VAL 342 -0.0001

VAL 342 ILE 343 0.0003

ILE 343 ILE 344 -0.0000

ILE 344 LYS 345 -0.0000

LYS 345 ASN 346 0.0001

ASN 346 ASN 347 0.0003

ASN 347 LEU 348 0.0000

LEU 348 LYS 349 0.0002

LYS 349 ASP 350 0.0000

ASP 350 CYS 351 0.0015

CYS 351 GLY 352 0.0003

GLY 352 LEU 353 -0.0000

LEU 353 PHE 354 -0.0000

PHE 354 LEU 30 -0.0099

LEU 30 SER 31 0.0003

SER 31 GLN 32 -0.0004

GLN 32 ILE 33 0.0003

ILE 33 THR 34 0.0002

THR 34 ASN 35 0.0003

ASN 35 ASN 36 -0.0002

ASN 36 ILE 37 0.0002

ILE 37 ASP 38 0.0001

ASP 38 PRO 39 0.0003

PRO 39 VAL 40 0.0004

VAL 40 GLY 41 0.0003

GLY 41 ARG 42 -0.0003

ARG 42 ILE 43 -0.0017

ILE 43 GLN 44 -0.0003

GLN 44 MET 45 -0.0001

MET 45 ARG 46 -0.0001

ARG 46 THR 47 0.0002

THR 47 ARG 48 0.0001

ARG 48 ARG 49 0.0000

ARG 49 THR 50 -0.0002

THR 50 LEU 51 0.0003

LEU 51 ARG 52 -0.0003

ARG 52 GLY 53 0.0001

GLY 53 HIS 54 0.0001

HIS 54 LEU 55 -0.0000

LEU 55 ALA 56 0.0010

ALA 56 LYS 57 0.0001

LYS 57 ILE 58 0.0003

ILE 58 TYR 59 -0.0003

TYR 59 ALA 60 0.0001

ALA 60 MET 61 -0.0004

MET 61 HIS 62 -0.0000

HIS 62 TRP 63 -0.0002

TRP 63 GLY 64 0.0002

GLY 64 THR 65 -0.0004

THR 65 ASP 66 0.0002

ASP 66 SER 67 -0.0002

SER 67 ARG 68 -0.0001

ARG 68 LEU 69 -0.0028

LEU 69 LEU 70 -0.0002

LEU 70 VAL 71 0.0003

VAL 71 SER 72 -0.0001

SER 72 ALA 73 0.0001

ALA 73 SER 74 -0.0004

SER 74 GLN 75 0.0003

GLN 75 ASP 76 0.0002

ASP 76 GLY 77 -0.0001

GLY 77 LYS 78 0.0002

LYS 78 LEU 79 -0.0001

LEU 79 ILE 80 0.0002

ILE 80 ILE 81 -0.0001

ILE 81 TRP 82 0.0040

TRP 82 ASP 83 -0.0001

ASP 83 SER 84 0.0002

SER 84 TYR 85 -0.0002

TYR 85 THR 86 0.0001

THR 86 THR 87 -0.0002

THR 87 ASN 88 -0.0004

ASN 88 LYS 89 -0.0000

LYS 89 VAL 90 0.0001

VAL 90 HIS 91 0.0005

HIS 91 ALA 92 -0.0002

ALA 92 ILE 93 -0.0004

ILE 93 PRO 94 0.0002

PRO 94 LEU 95 0.0163

LEU 95 ARG 96 0.0001

ARG 96 SER 97 0.0002

SER 97 SER 98 -0.0000

SER 98 TRP 99 0.0002

TRP 99 VAL 100 -0.0003

VAL 100 MET 101 -0.0002

MET 101 THR 102 -0.0002

THR 102 CYS 103 -0.0001

CYS 103 ALA 104 0.0002

ALA 104 TYR 105 0.0000

TYR 105 ALA 106 0.0001

ALA 106 PRO 107 0.0000

PRO 107 SER 108 0.0092

SER 108 GLY 109 -0.0002

GLY 109 ASN 110 -0.0001

ASN 110 TYR 111 -0.0000

TYR 111 VAL 112 0.0003

VAL 112 ALA 113 -0.0004

ALA 113 CYS 114 -0.0002

CYS 114 GLY 115 0.0001

GLY 115 GLY 116 0.0002

GLY 116 LEU 117 -0.0001

LEU 117 ASP 118 -0.0000

ASP 118 ASN 119 0.0002

ASN 119 ILE 120 0.0003

ILE 120 CYS 121 0.0117

CYS 121 SER 122 0.0002

SER 122 ILE 123 0.0001

ILE 123 TYR 124 -0.0002

TYR 124 ASN 125 -0.0001

ASN 125 LEU 126 0.0002

LEU 126 LYS 127 0.0001

LYS 127 THR 128 0.0002

THR 128 ARG 129 0.0002

ARG 129 GLU 130 -0.0001

GLU 130 GLY 131 0.0000

GLY 131 ASN 132 -0.0003

ASN 132 VAL 133 -0.0001

VAL 133 ARG 134 0.0181

ARG 134 VAL 135 -0.0001

VAL 135 SER 136 0.0002

SER 136 ARG 137 -0.0001

ARG 137 GLU 138 0.0002

GLU 138 LEU 139 -0.0003

LEU 139 ALA 140 -0.0002

ALA 140 GLY 141 0.0002

GLY 141 HIS 142 0.0003

HIS 142 THR 143 -0.0003

THR 143 GLY 144 0.0001

GLY 144 TYR 145 0.0000

TYR 145 LEU 146 -0.0001

LEU 146 SER 147 0.0014

SER 147 CYS 148 -0.0001

CYS 148 CYS 149 0.0002

CYS 149 ARG 150 -0.0001

ARG 150 PHE 151 0.0004

PHE 151 LEU 152 -0.0001

LEU 152 ASP 153 -0.0001

ASP 153 ASP 154 -0.0002

ASP 154 ASN 155 0.0001

ASN 155 GLN 156 0.0000

GLN 156 ILE 157 -0.0004

ILE 157 VAL 158 -0.0001

VAL 158 THR 159 0.0003

THR 159 SER 160 0.0035

SER 160 SER 161 -0.0001

SER 161 GLY 162 -0.0001

GLY 162 ASP 163 0.0002

ASP 163 THR 164 0.0001

THR 164 THR 165 -0.0001

THR 165 CYS 166 0.0003

CYS 166 ALA 167 -0.0002

ALA 167 LEU 168 0.0002

LEU 168 TRP 169 0.0001

TRP 169 ASP 170 0.0001

ASP 170 ILE 171 -0.0002

ILE 171 GLU 172 0.0000

GLU 172 THR 173 -0.0014

THR 173 GLY 174 -0.0002

GLY 174 GLN 175 0.0002

GLN 175 GLN 176 -0.0001

GLN 176 THR 177 -0.0003

THR 177 THR 178 -0.0003

THR 178 THR 179 0.0002

THR 179 PHE 180 0.0000

PHE 180 THR 181 0.0001

THR 181 GLY 182 0.0001

GLY 182 HIS 183 -0.0001

HIS 183 THR 184 -0.0000

THR 184 GLY 185 0.0003

GLY 185 ASP 186 -0.0008

ASP 186 VAL 187 -0.0003

VAL 187 MET 188 0.0001

MET 188 SER 189 0.0001

SER 189 LEU 190 -0.0002

LEU 190 SER 191 -0.0001

SER 191 LEU 192 0.0000

LEU 192 ALA 193 0.0004

ALA 193 PRO 194 -0.0002

PRO 194 ASP 195 0.0002

ASP 195 THR 196 0.0005

THR 196 ARG 197 0.0000

ARG 197 LEU 198 -0.0001

LEU 198 PHE 199 0.0012

PHE 199 VAL 200 0.0004

VAL 200 SER 201 -0.0003

SER 201 GLY 202 0.0002

GLY 202 ALA 203 -0.0001

ALA 203 CYS 204 -0.0001

CYS 204 ASP 205 -0.0002

ASP 205 ALA 206 -0.0001

ALA 206 SER 207 -0.0000

SER 207 ALA 208 0.0002

ALA 208 LYS 209 -0.0001

LYS 209 LEU 210 0.0003

LEU 210 TRP 211 -0.0002

TRP 211 ASP 212 -0.0013

ASP 212 VAL 213 0.0002

VAL 213 ARG 214 -0.0002

ARG 214 GLU 215 -0.0002

GLU 215 GLY 216 -0.0003

GLY 216 MET 217 0.0001

MET 217 CYS 218 -0.0001

CYS 218 ARG 219 0.0000

ARG 219 GLN 220 -0.0001

GLN 220 THR 221 0.0003

THR 221 PHE 222 -0.0002

PHE 222 THR 223 -0.0003

THR 223 GLY 224 0.0002

GLY 224 HIS 225 0.0014

HIS 225 GLU 226 -0.0001

GLU 226 SER 227 -0.0001

SER 227 ASP 228 0.0002

ASP 228 ILE 229 0.0002

ILE 229 ASN 230 -0.0003

ASN 230 ALA 231 0.0001

ALA 231 ILE 232 0.0000

ILE 232 CYS 233 -0.0003

CYS 233 PHE 234 0.0003

PHE 234 PHE 235 -0.0001

PHE 235 PRO 236 -0.0001

PRO 236 ASN 237 -0.0003

ASN 237 GLY 238 -0.0000

GLY 238 ASN 239 -0.0003

ASN 239 ALA 240 -0.0000

ALA 240 PHE 241 -0.0004

PHE 241 ALA 242 -0.0003

ALA 242 THR 243 0.0003

THR 243 GLY 244 0.0001

GLY 244 SER 245 -0.0001

SER 245 ASP 246 0.0003

ASP 246 ASP 247 -0.0002

ASP 247 ALA 248 -0.0003

ALA 248 THR 249 0.0000

THR 249 CYS 250 -0.0000

CYS 250 ARG 251 -0.0010

ARG 251 LEU 252 0.0004

LEU 252 PHE 253 -0.0003

PHE 253 ASP 254 0.0002

ASP 254 LEU 255 -0.0000

LEU 255 ARG 256 0.0002

ARG 256 ALA 257 -0.0005

ALA 257 ASP 258 -0.0000

ASP 258 GLN 259 0.0001

GLN 259 GLU 260 -0.0004

GLU 260 LEU 261 0.0001

LEU 261 MET 262 -0.0001

MET 262 THR 263 -0.0002

THR 263 TYR 264 0.0006

TYR 264 SER 265 0.0001

SER 265 HIS 266 0.0002

HIS 266 ASP 267 -0.0002

ASP 267 ASN 268 -0.0002

ASN 268 ILE 269 -0.0002

ILE 269 ILE 270 0.0001

ILE 270 CYS 271 0.0003

CYS 271 GLY 272 -0.0003

GLY 272 ILE 273 0.0001

ILE 273 THR 274 -0.0003

THR 274 SER 275 0.0001

SER 275 VAL 276 -0.0002

VAL 276 SER 277 0.0014

SER 277 PHE 278 -0.0006

PHE 278 SER 279 0.0001

SER 279 LYS 280 -0.0003

LYS 280 SER 281 -0.0000

SER 281 GLY 282 0.0005

GLY 282 ARG 283 0.0003

ARG 283 LEU 284 -0.0002

LEU 284 LEU 285 -0.0001

LEU 285 LEU 286 0.0002

LEU 286 ALA 287 0.0001

ALA 287 GLY 288 0.0000

GLY 288 TYR 289 -0.0002

TYR 289 ASP 290 -0.0009

ASP 290 ASP 291 -0.0000

ASP 291 PHE 292 -0.0004

PHE 292 ASN 293 0.0001

ASN 293 CYS 294 0.0003

CYS 294 ASN 295 0.0001

ASN 295 VAL 296 -0.0002

VAL 296 TRP 297 -0.0003

TRP 297 ASP 298 0.0002

ASP 298 ALA 299 0.0003

ALA 299 LEU 300 -0.0001

LEU 300 LYS 301 0.0000

LYS 301 ALA 302 0.0002

ALA 302 ASP 303 -0.0004

ASP 303 ARG 304 -0.0005

ARG 304 ALA 305 -0.0005

ALA 305 GLY 306 -0.0002

GLY 306 VAL 307 0.0003

VAL 307 LEU 308 0.0002

LEU 308 ALA 309 -0.0003

ALA 309 GLY 310 0.0002

GLY 310 HIS 311 -0.0001

HIS 311 ASP 312 -0.0002

ASP 312 ASN 313 0.0003

ASN 313 ARG 314 -0.0001

ARG 314 VAL 315 0.0004

VAL 315 SER 316 0.0014

SER 316 CYS 317 -0.0003

CYS 317 LEU 318 0.0001

LEU 318 GLY 319 0.0004

GLY 319 VAL 320 0.0002

VAL 320 THR 321 -0.0001

THR 321 ASP 322 -0.0000

ASP 322 ASP 323 0.0001

ASP 323 GLY 324 0.0000

GLY 324 MET 325 -0.0000

MET 325 ALA 326 0.0000

ALA 326 VAL 327 -0.0003

VAL 327 ALA 328 -0.0001

ALA 328 THR 329 -0.0011

THR 329 GLY 330 0.0001

GLY 330 SER 331 0.0001

SER 331 TRP 332 -0.0001

TRP 332 ASP 333 -0.0000

ASP 333 SER 334 -0.0003

SER 334 PHE 335 -0.0004

PHE 335 LEU 336 -0.0002

LEU 336 LYS 337 -0.0001

LYS 337 ILE 338 0.0001

ILE 338 TRP 339 -0.0001

TRP 339 ASN 340 0.0003

ASN 340 LYS 29 -0.0004

LYS 29 VAL 30 0.0001

VAL 30 SER 31 -0.0001

SER 31 LYS 32 -0.0003

LYS 32 ALA 33 -0.0001

ALA 33 ALA 34 -0.0005

ALA 34 ALA 35 0.0003

ALA 35 ASP 36 -0.0002

ASP 36 LEU 37 0.0001

LEU 37 MET 38 -0.0000

MET 38 ALA 39 -0.0000

ALA 39 TYR 40 0.0003

TYR 40 CYS 41 0.0001

CYS 41 GLU 42 -0.0000

GLU 42 ALA 43 -0.0002

ALA 43 HIS 44 0.0002

HIS 44 ALA 45 -0.0003

ALA 45 LYS 46 0.0003

LYS 46 GLU 47 0.0001

GLU 47 ASP 48 0.0004

ASP 48 PRO 49 -0.0001

PRO 49 LEU 50 0.0002

LEU 50 LEU 51 0.0002

LEU 51 THR 52 0.0003

THR 52 PRO 53 -0.0001

PRO 53 VAL 54 0.0002

VAL 54 PRO 55 -0.0008

PRO 55 ALA 56 0.0003

ALA 56 SER 57 0.0001

SER 57 GLU 58 -0.0000

GLU 58 ASN 59 -0.0003

ASN 59 PRO 60 0.0001

PRO 60 PHE 61 -0.0003

PHE 61 VAL 2 -0.0007

VAL 2 GLN 3 -0.0003

GLN 3 LEU 4 0.0004

LEU 4 VAL 5 0.0003

VAL 5 GLU 6 -0.0001

GLU 6 SER 7 0.0000

SER 7 GLY 8 0.0000

GLY 8 GLY 9 -0.0003

GLY 9 GLY 10 0.0002

GLY 10 LEU 11 0.0000

LEU 11 VAL 12 -0.0003

VAL 12 GLN 13 -0.0001

GLN 13 PRO 14 0.0003

PRO 14 GLY 15 -0.0010

GLY 15 GLY 16 0.0001

GLY 16 SER 17 -0.0002

SER 17 ARG 18 0.0004

ARG 18 LYS 19 -0.0001

LYS 19 LEU 20 -0.0002

LEU 20 SER 21 0.0000

SER 21 CYS 22 0.0002

CYS 22 SER 23 0.0002

SER 23 ALA 24 -0.0003

ALA 24 SER 25 0.0002

SER 25 GLY 26 0.0002

GLY 26 PHE 27 -0.0002

PHE 27 ALA 28 0.0000

ALA 28 PHE 29 -0.0000

PHE 29 SER 30 0.0004

SER 30 SER 31 -0.0000

SER 31 PHE 32 0.0001

PHE 32 GLY 33 -0.0001

GLY 33 MET 34 -0.0000

MET 34 HIS 35 -0.0001

HIS 35 TRP 36 -0.0002

TRP 36 VAL 37 -0.0003

VAL 37 ARG 38 -0.0004

ARG 38 GLN 39 0.0001

GLN 39 ALA 40 -0.0001

ALA 40 PRO 41 0.0052

PRO 41 GLU 42 -0.0002

GLU 42 LYS 43 0.0002

LYS 43 GLY 44 0.0000

GLY 44 LEU 45 -0.0001

LEU 45 GLU 46 0.0005

GLU 46 TRP 47 -0.0004

TRP 47 VAL 48 0.0003

VAL 48 ALA 49 0.0003

ALA 49 TYR 50 -0.0006

TYR 50 ILE 51 0.0002

ILE 51 SER 52 -0.0002

SER 52 SER 53 -0.0000

SER 53 GLY 54 -0.0015

GLY 54 SER 55 -0.0001

SER 55 GLY 56 0.0002

GLY 56 THR 57 -0.0001

THR 57 ILE 58 0.0001

ILE 58 TYR 59 0.0003

TYR 59 TYR 60 0.0003

TYR 60 ALA 61 -0.0002

ALA 61 ASP 62 -0.0002

ASP 62 THR 63 0.0003

THR 63 VAL 64 0.0001

VAL 64 LYS 65 0.0000

LYS 65 GLY 66 0.0000

GLY 66 ARG 67 -0.0052

ARG 67 PHE 68 -0.0004

PHE 68 THR 69 0.0004

THR 69 ILE 70 -0.0003

ILE 70 SER 71 0.0006

SER 71 ARG 72 -0.0002

ARG 72 ASP 73 -0.0002

ASP 73 ASP 74 0.0003

ASP 74 PRO 75 -0.0003

PRO 75 LYS 76 -0.0001

LYS 76 ASN 77 0.0002

ASN 77 THR 78 0.0001

THR 78 LEU 79 0.0001

LEU 79 PHE 80 -0.0017

PHE 80 LEU 81 0.0002

LEU 81 GLN 82 -0.0002

GLN 82 MET 83 0.0003

MET 83 THR 84 0.0000

THR 84 SER 85 -0.0003

SER 85 LEU 86 -0.0002

LEU 86 ARG 87 0.0001

ARG 87 SER 88 0.0001

SER 88 GLU 89 -0.0002

GLU 89 ASP 90 -0.0000

ASP 90 THR 91 0.0001

THR 91 ALA 92 -0.0002

ALA 92 MET 93 0.0016

MET 93 TYR 94 0.0001

TYR 94 TYR 95 -0.0000

TYR 95 CYS 96 0.0002

CYS 96 VAL 97 -0.0002

VAL 97 ARG 98 0.0002

ARG 98 SER 99 -0.0001

SER 99 ILE 100 -0.0000

ILE 100 TYR 101 0.0002

TYR 101 TYR 102 0.0003

TYR 102 TYR 103 0.0001

TYR 103 GLY 104 0.0000

GLY 104 SER 105 -0.0001

SER 105 SER 106 0.0041

SER 106 PRO 107 -0.0003

PRO 107 PHE 108 -0.0002

PHE 108 ASP 109 0.0002

ASP 109 PHE 110 0.0003

PHE 110 TRP 111 -0.0004

TRP 111 GLY 112 -0.0002

GLY 112 GLN 113 0.0003

GLN 113 GLY 114 -0.0003

GLY 114 THR 115 0.0001

THR 115 THR 116 0.0002

THR 116 LEU 117 -0.0000

LEU 117 THR 118 -0.0000

THR 118 VAL 119 0.0022

VAL 119 SER 120 0.0000

SER 120 SER 121 -0.0002

SER 121 SER 136 0.0004

SER 136 ASP 137 0.0001

ASP 137 ILE 138 -0.0000

ILE 138 VAL 139 -0.0001

VAL 139 MET 140 0.0002

MET 140 THR 141 -0.0003

THR 141 GLN 142 0.0000

GLN 142 ALA 143 0.0002

ALA 143 THR 144 -0.0002

THR 144 SER 145 0.0002

SER 145 SER 146 0.0000

SER 146 VAL 147 -0.0002

VAL 147 PRO 148 0.0000

PRO 148 VAL 149 -0.0003

VAL 149 THR 150 0.0000

THR 150 PRO 151 -0.0001

PRO 151 GLY 152 0.0001

GLY 152 GLU 153 0.0003

GLU 153 SER 154 0.0000

SER 154 VAL 155 -0.0003

VAL 155 SER 156 -0.0001

SER 156 ILE 157 0.0003

ILE 157 SER 158 -0.0000

SER 158 CYS 159 0.0002

CYS 159 ARG 160 -0.0000

ARG 160 SER 161 -0.0000

SER 161 SER 162 -0.0003

SER 162 LYS 163 0.0005

LYS 163 SER 164 -0.0004

SER 164 LEU 165 -0.0001

LEU 165 LEU 166 -0.0001

LEU 166 HIS 167 0.0002

HIS 167 SER 168 -0.0001

SER 168 ASN 169 0.0002

ASN 169 GLY 170 0.0003

GLY 170 ASN 171 0.0001

ASN 171 THR 172 -0.0002

THR 172 TYR 173 -0.0001

TYR 173 LEU 174 0.0001

LEU 174 TYR 175 -0.0020

TYR 175 TRP 176 0.0000

TRP 176 PHE 177 0.0001

PHE 177 LEU 178 0.0000

LEU 178 GLN 179 0.0004

GLN 179 ARG 180 -0.0004

ARG 180 PRO 181 -0.0003

PRO 181 GLY 182 0.0001

GLY 182 GLN 183 0.0001

GLN 183 SER 184 0.0000

SER 184 PRO 185 -0.0000

PRO 185 GLN 186 -0.0001

GLN 186 LEU 187 0.0002

LEU 187 LEU 188 -0.0030

LEU 188 ILE 189 0.0001

ILE 189 TYR 190 -0.0002

TYR 190 ARG 191 0.0001

ARG 191 MET 192 0.0004

MET 192 SER 193 0.0002

SER 193 ASN 194 -0.0002

ASN 194 LEU 195 0.0004

LEU 195 ALA 196 -0.0004

ALA 196 SER 197 0.0000

SER 197 GLY 198 0.0002

GLY 198 VAL 199 0.0003

VAL 199 PRO 200 -0.0002

PRO 200 ASP 201 -0.0032

ASP 201 ARG 202 0.0003

ARG 202 PHE 203 -0.0002

PHE 203 SER 204 -0.0000

SER 204 GLY 205 -0.0002

GLY 205 SER 206 0.0001

SER 206 GLY 207 0.0001

GLY 207 SER 208 -0.0000

SER 208 GLY 209 0.0001

GLY 209 THR 210 -0.0000

THR 210 ALA 211 0.0002

ALA 211 PHE 212 -0.0002

PHE 212 THR 213 -0.0002

THR 213 LEU 214 0.0011

LEU 214 THR 215 -0.0001

THR 215 ILE 216 -0.0002

ILE 216 SER 217 -0.0002

SER 217 ARG 218 -0.0003

ARG 218 LEU 219 -0.0001

LEU 219 GLU 220 0.0003

GLU 220 ALA 221 -0.0001

ALA 221 GLU 222 0.0003

GLU 222 ASP 223 -0.0002

ASP 223 VAL 224 -0.0002

VAL 224 GLY 225 -0.0000

GLY 225 VAL 226 0.0001

VAL 226 TYR 227 0.0007

TYR 227 TYR 228 -0.0002

TYR 228 CYS 229 -0.0001

CYS 229 MET 230 0.0001

MET 230 GLN 231 0.0002

GLN 231 HIS 232 0.0001

HIS 232 LEU 233 -0.0002

LEU 233 GLU 234 -0.0003

GLU 234 TYR 235 -0.0003

TYR 235 PRO 236 0.0001

PRO 236 LEU 237 0.0003

LEU 237 THR 238 -0.0000

THR 238 PHE 239 -0.0001

PHE 239 GLY 240 0.0005

GLY 240 ALA 241 0.0000

ALA 241 GLY 242 0.0004

GLY 242 THR 243 -0.0002

THR 243 LYS 244 -0.0001

LYS 244 LEU 245 -0.0000

LEU 245 GLU 246 0.0000

GLU 246 LEU 247 0.0003

LEU 247 VAL 2 -0.0087

VAL 2 GLN 3 0.0001

GLN 3 LEU 4 -0.0001

LEU 4 VAL 5 -0.0001

VAL 5 GLN 6 0.0000

GLN 6 SER 7 -0.0000

SER 7 GLY 8 0.0001

GLY 8 GLY 9 -0.0001

GLY 9 GLY 10 0.0000

GLY 10 LEU 11 0.0000

LEU 11 VAL 12 0.0003

VAL 12 GLN 13 -0.0004

GLN 13 ALA 14 0.0001

ALA 14 GLY 15 -0.0004

GLY 15 GLY 16 0.0004

GLY 16 SER 17 -0.0002

SER 17 LEU 18 -0.0001

LEU 18 ARG 19 0.0001

ARG 19 LEU 20 -0.0001

LEU 20 SER 21 -0.0001

SER 21 CYS 22 -0.0001

CYS 22 ALA 23 0.0003

ALA 23 ALA 24 -0.0003

ALA 24 SER 25 0.0004

SER 25 VAL 26 -0.0001

VAL 26 ARG 27 0.0002

ARG 27 PHE 28 -0.0016

PHE 28 PHE 29 -0.0002

PHE 29 SER 30 -0.0002

SER 30 ILE 31 -0.0002

ILE 31 ASN 32 0.0004

ASN 32 THR 33 -0.0002

THR 33 MET 34 0.0001

MET 34 GLY 35 0.0002

GLY 35 TRP 36 -0.0000

TRP 36 TYR 37 -0.0002

TYR 37 ARG 38 -0.0000

ARG 38 GLN 39 0.0001

GLN 39 ALA 40 -0.0002

ALA 40 PRO 41 0.0021

PRO 41 GLY 42 0.0000

GLY 42 LYS 43 0.0003

LYS 43 GLN 44 0.0001

GLN 44 ARG 45 0.0003

ARG 45 GLU 46 -0.0002

GLU 46 LEU 47 0.0003

LEU 47 VAL 48 -0.0000

VAL 48 ALA 49 0.0002

ALA 49 ASP 50 -0.0001

ASP 50 ILE 51 0.0002

ILE 51 THR 52 0.0003

THR 52 SER 53 0.0000

SER 53 SER 54 0.0007

SER 54 GLY 55 -0.0002

GLY 55 SER 56 -0.0001

SER 56 THR 57 0.0001

THR 57 ASN 58 -0.0003

ASN 58 TYR 59 -0.0000

TYR 59 ALA 60 -0.0000

ALA 60 ASP 61 0.0002

ASP 61 SER 62 0.0002

SER 62 GLY 63 -0.0001

GLY 63 LYS 64 0.0001

LYS 64 GLY 65 -0.0004

GLY 65 ARG 66 0.0001

ARG 66 PHE 67 0.0010

PHE 67 THR 68 -0.0001

THR 68 ILE 69 -0.0001

ILE 69 SER 70 -0.0001

SER 70 ARG 71 -0.0003

ARG 71 ASP 72 0.0001

ASP 72 ASN 73 -0.0003

ASN 73 ALA 74 -0.0000

ALA 74 LYS 75 -0.0000

LYS 75 ASN 76 -0.0002

ASN 76 THR 77 0.0003

THR 77 VAL 78 -0.0001

VAL 78 TYR 79 0.0001

TYR 79 LEU 80 -0.0003

LEU 80 GLN 81 -0.0002

GLN 81 MET 82 0.0003

MET 82 ASN 83 -0.0001

ASN 83 ARG 84 0.0001

ARG 84 LEU 85 -0.0001

LEU 85 LYS 86 -0.0000

LYS 86 PRO 87 0.0004

PRO 87 GLU 88 0.0002

GLU 88 ASP 89 0.0004

ASP 89 THR 90 0.0002

THR 90 ALA 91 0.0002

ALA 91 VAL 92 0.0001

VAL 92 TYR 93 -0.0013

TYR 93 TYR 94 -0.0002

TYR 94 CYS 95 0.0000

CYS 95 HIS 96 -0.0001

HIS 96 ALA 97 -0.0001

ALA 97 ASP 98 0.0004

ASP 98 TYR 99 -0.0001

TYR 99 LYS 100 0.0000

LYS 100 TYR 101 0.0002

TYR 101 THR 102 0.0000

THR 102 THR 103 0.0004

THR 103 HIS 104 -0.0002

HIS 104 ASN 105 -0.0000

ASN 105 THR 106 -0.0018

THR 106 ALA 107 -0.0001

ALA 107 TRP 108 -0.0000

TRP 108 GLY 109 0.0001

GLY 109 GLN 110 -0.0003

GLN 110 GLY 111 -0.0002

GLY 111 THR 112 0.0003

THR 112 GLN 113 0.0004

GLN 113 VAL 114 -0.0003

VAL 114 THR 115 -0.0004

THR 115 VAL 116 0.0002

VAL 116 SER 117 -0.0002

SER 117 SER 118 0.0002

SER 118 VAL 2 0.0008

VAL 2 GLN 3 0.0000

GLN 3 LEU 4 -0.0002

LEU 4 VAL 5 -0.0003

VAL 5 GLN 6 0.0001

GLN 6 SER 7 -0.0003

SER 7 GLY 8 0.0003

GLY 8 GLY 9 -0.0001

GLY 9 GLY 10 0.0001

GLY 10 LEU 11 0.0000

LEU 11 VAL 12 0.0000

VAL 12 GLN 13 -0.0003

GLN 13 ALA 14 -0.0001

ALA 14 GLY 15 -0.0009

GLY 15 GLY 16 0.0002

GLY 16 SER 17 -0.0002

SER 17 LEU 18 0.0004

LEU 18 ARG 19 -0.0001

ARG 19 LEU 20 0.0001

LEU 20 SER 21 -0.0000

SER 21 CYS 22 -0.0002

CYS 22 ALA 23 -0.0001

ALA 23 ALA 24 0.0003

ALA 24 SER 25 0.0001

SER 25 VAL 26 -0.0003

VAL 26 ARG 27 0.0003

ARG 27 PHE 28 0.0004

PHE 28 PHE 29 -0.0000

PHE 29 SER 30 0.0000

SER 30 ILE 31 0.0001

ILE 31 ASN 32 0.0001

ASN 32 THR 33 0.0000

THR 33 MET 34 0.0002

MET 34 GLY 35 0.0002

GLY 35 TRP 36 -0.0002

TRP 36 TYR 37 0.0001

TYR 37 ARG 38 0.0000

ARG 38 GLN 39 -0.0002

GLN 39 ALA 40 0.0002

ALA 40 PRO 41 0.0027

PRO 41 GLY 42 -0.0000

GLY 42 LYS 43 0.0001

LYS 43 GLN 44 0.0001

GLN 44 ARG 45 0.0003

ARG 45 GLU 46 -0.0004

GLU 46 LEU 47 -0.0001

LEU 47 VAL 48 0.0002

VAL 48 ALA 49 -0.0002

ALA 49 ASP 50 0.0002

ASP 50 ILE 51 0.0000

ILE 51 THR 52 0.0001

THR 52 SER 53 -0.0002

SER 53 SER 54 0.0003

SER 54 GLY 55 -0.0001

GLY 55 SER 56 0.0001

SER 56 THR 57 -0.0001

THR 57 ASN 58 0.0000

ASN 58 TYR 59 0.0000

TYR 59 ALA 60 0.0001

ALA 60 ASP 61 -0.0001

ASP 61 SER 62 0.0001

SER 62 GLY 63 -0.0003

GLY 63 LYS 64 0.0001

LYS 64 GLY 65 0.0003

GLY 65 ARG 66 -0.0002

ARG 66 PHE 67 0.0013

PHE 67 THR 68 -0.0004

THR 68 ILE 69 -0.0002

ILE 69 SER 70 0.0000

SER 70 ARG 71 -0.0001

ARG 71 ASP 72 0.0000

ASP 72 ASN 73 0.0003

ASN 73 ALA 74 -0.0002

ALA 74 LYS 75 -0.0001

LYS 75 ASN 76 -0.0000

ASN 76 THR 77 0.0001

THR 77 VAL 78 0.0004

VAL 78 TYR 79 0.0001

TYR 79 LEU 80 -0.0003

LEU 80 GLN 81 0.0004

GLN 81 MET 82 -0.0004

MET 82 ASN 83 -0.0001

ASN 83 ARG 84 0.0000

ARG 84 LEU 85 0.0001

LEU 85 LYS 86 0.0001

LYS 86 PRO 87 0.0000

PRO 87 GLU 88 0.0000

GLU 88 ASP 89 0.0000

ASP 89 THR 90 0.0003

THR 90 ALA 91 -0.0003

ALA 91 VAL 92 0.0003

VAL 92 TYR 93 -0.0020

TYR 93 TYR 94 -0.0002

TYR 94 CYS 95 0.0003

CYS 95 HIS 96 0.0001

HIS 96 ALA 97 -0.0002

ALA 97 ASP 98 -0.0004

ASP 98 TYR 99 0.0003

TYR 99 LYS 100 -0.0002

LYS 100 TYR 101 -0.0002

TYR 101 THR 102 -0.0001

THR 102 THR 103 -0.0001

THR 103 HIS 104 -0.0001

HIS 104 ASN 105 -0.0001

ASN 105 THR 106 -0.0018

THR 106 ALA 107 -0.0001

ALA 107 TRP 108 -0.0002

TRP 108 GLY 109 0.0000

GLY 109 GLN 110 0.0000

GLN 110 GLY 111 -0.0001

GLY 111 THR 112 0.0003

THR 112 GLN 113 -0.0003

GLN 113 VAL 114 0.0003

VAL 114 THR 115 -0.0001

THR 115 VAL 116 -0.0002

VAL 116 SER 117 0.0004

SER 117 SER 118 0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** floflo3 ***

CA strain for 2403041948001590542

--- normal mode 13 ---

Should you encounter any unexpected behaviour,
please let us know.

* floflo3 *