Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE 06-MAY-21 7OG5 *

CA strain for 22121317415457420

--- normal mode 8 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
SER 1 ARG 2 -0.0005

ARG 2 ARG 3 0.0004

ARG 3 PHE 4 0.0001

PHE 4 VAL 5 -0.0002

VAL 5 LEU 6 -0.0004

LEU 6 ASP 7 0.0004

ASP 7 THR 8 -0.0002

THR 8 SER 9 -0.0000

SER 9 VAL 10 -0.0001

VAL 10 PHE 11 -0.0002

PHE 11 THR 12 0.0001

THR 12 ASN 13 -0.0002

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0003

VAL 16 TYR 17 0.0001

TYR 17 LEU 18 0.0000

LEU 18 ARG 19 0.0001

ARG 19 PHE 20 0.0000

PHE 20 ASP 21 0.0058

ASP 21 GLU 22 0.0000

GLU 22 GLU 23 0.0002

GLU 23 PRO 24 -0.0004

PRO 24 MET 25 0.0000

MET 25 GLN 26 0.0002

GLN 26 ALA 27 0.0002

ALA 27 ILE 28 0.0003

ILE 28 SER 29 0.0002

SER 29 VAL 30 -0.0004

VAL 30 PHE 31 0.0075

PHE 31 LEU 32 -0.0003

LEU 32 GLY 33 -0.0003

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 -0.0005

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 0.0002

ARG 37 ALA 38 0.0000

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 0.0001

ALA 40 GLU 41 -0.0276

GLU 41 PHE 42 0.0002

PHE 42 TYR 43 0.0001

TYR 43 MET 44 0.0003

MET 44 PRO 45 -0.0000

PRO 45 GLY 46 0.0002

GLY 46 PRO 47 0.0002

PRO 47 VAL 48 -0.0002

VAL 48 TYR 49 -0.0000

TYR 49 GLN 50 -0.0002

GLN 50 GLU 51 0.0085

GLU 51 LEU 52 -0.0001

LEU 52 CYS 53 0.0000

CYS 53 ASN 54 0.0000

ASN 54 LEU 55 -0.0001

LEU 55 ARG 56 -0.0005

ARG 56 SER 57 0.0001

SER 57 MET 58 0.0001

MET 58 ASP 59 0.0000

ASP 59 LEU 60 -0.0001

LEU 60 ILE 61 0.0194

ILE 61 GLY 62 -0.0001

GLY 62 ALA 63 0.0002

ALA 63 GLU 64 -0.0002

GLU 64 PHE 65 -0.0004

PHE 65 GLU 66 -0.0000

GLU 66 THR 67 -0.0001

THR 67 GLU 68 0.0002

GLU 68 VAL 69 0.0000

VAL 69 TYR 70 0.0001

TYR 70 ILE 71 -0.0099

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0000

SER 73 PRO 74 0.0001

PRO 74 ARG 75 -0.0003

ARG 75 ARG 76 -0.0001

ARG 76 PHE 77 0.0001

PHE 77 SER 78 -0.0001

SER 78 MET 79 -0.0001

MET 79 THR 80 0.0002

THR 80 ILE 81 0.0025

ILE 81 PRO 82 0.0001

PRO 82 SER 83 0.0001

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 0.0004

VAL 85 LEU 86 -0.0002

LEU 86 TYR 87 0.0000

TYR 87 GLU 88 0.0001

GLU 88 PHE 89 0.0004

PHE 89 ILE 90 0.0000

ILE 90 GLU 91 0.0029

GLU 91 GLU 92 0.0000

GLU 92 VAL 93 -0.0000

VAL 93 ARG 94 0.0003

ARG 94 THR 95 0.0000

THR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0002

ILE 97 GLN 98 -0.0002

GLN 98 GLU 131 0.0028

GLU 131 ALA 132 -0.0004

ALA 132 MET 133 0.0001

MET 133 ARG 134 0.0003

ARG 134 ARG 135 0.0002

ARG 135 GLY 136 0.0003

GLY 136 ILE 137 0.0001

ILE 137 LEU 138 -0.0001

LEU 138 ASP 139 0.0005

ASP 139 SER 140 -0.0001

SER 140 ARG 141 -0.0113

ARG 141 GLU 142 -0.0002

GLU 142 ASP 143 0.0000

ASP 143 ILE 144 0.0001

ILE 144 ASP 145 0.0002

ASP 145 VAL 146 -0.0004

VAL 146 VAL 147 0.0002

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0001

LEU 149 ALA 150 -0.0001

ALA 150 TYR 151 0.0065

TYR 151 GLU 152 0.0003

GLU 152 LEU 153 0.0000

LEU 153 ASP 154 0.0001

ASP 154 ALA 155 0.0000

ALA 155 THR 156 0.0004

THR 156 LEU 157 -0.0001

LEU 157 VAL 158 0.0002

VAL 158 SER 159 -0.0002

SER 159 ALA 160 -0.0001

ALA 160 ASP 161 0.0071

ASP 161 GLU 162 -0.0002

GLU 162 GLY 163 0.0004

GLY 163 MET 164 0.0002

MET 164 ARG 165 -0.0003

ARG 165 LYS 166 -0.0002

LYS 166 PHE 167 -0.0003

PHE 167 ALA 168 0.0001

ALA 168 GLU 169 0.0001

GLU 169 ARG 170 -0.0001

ARG 170 ILE 171 -0.0077

ILE 171 GLY 172 -0.0002

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 -0.0002

LYS 174 LEU 175 -0.0005

LEU 175 VAL 176 0.0004

VAL 176 ASN 177 0.0003

ASN 177 PRO 178 -0.0001

PRO 178 ARG 179 -0.0003

ARG 179 TYR 180 -0.0000

TYR 180 LEU 181 -0.0252

LEU 181 ARG 182 0.0004

ARG 182 GLY 183 -0.0000

GLY 183 VAL 184 -0.0003

VAL 184 MET 185 0.0003

MET 185 GLN 186 -0.0000

GLN 186 ASN 187 0.0001

ASN 187 LEU 188 -0.0001

LEU 188 ALA 189 -0.0002

ALA 189 SER 1 0.0442

SER 1 ARG 2 -0.0001

ARG 2 ARG 3 -0.0000

ARG 3 PHE 4 -0.0002

PHE 4 VAL 5 -0.0003

VAL 5 LEU 6 0.0002

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 0.0001

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0003

VAL 10 PHE 11 -0.0092

PHE 11 THR 12 0.0001

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 -0.0000

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 0.0001

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 -0.0096

ASP 21 GLU 22 0.0000

GLU 22 GLU 23 -0.0004

GLU 23 PRO 24 0.0001

PRO 24 MET 25 0.0001

MET 25 GLN 26 -0.0000

GLN 26 ALA 27 -0.0001

ALA 27 ILE 28 -0.0001

ILE 28 SER 29 -0.0001

SER 29 VAL 30 0.0004

VAL 30 PHE 31 -0.0031

PHE 31 LEU 32 -0.0001

LEU 32 GLY 33 -0.0001

GLY 33 LEU 34 0.0003

LEU 34 ALA 35 0.0002

ALA 35 ARG 36 -0.0002

ARG 36 ARG 37 0.0001

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 -0.0002

ASP 39 ALA 40 -0.0002

ALA 40 GLU 41 0.0215

GLU 41 PHE 42 -0.0002

PHE 42 TYR 43 0.0002

TYR 43 MET 44 -0.0002

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0000

GLY 46 PRO 47 0.0001

PRO 47 VAL 48 0.0002

VAL 48 TYR 49 0.0003

TYR 49 GLN 50 -0.0005

GLN 50 GLU 51 0.0002

GLU 51 LEU 52 -0.0000

LEU 52 CYS 53 -0.0003

CYS 53 ASN 54 0.0002

ASN 54 LEU 55 0.0000

LEU 55 ARG 56 0.0000

ARG 56 SER 57 0.0006

SER 57 MET 58 0.0002

MET 58 ASP 59 -0.0000

ASP 59 LEU 60 -0.0003

LEU 60 ILE 61 0.0223

ILE 61 GLY 62 0.0004

GLY 62 ALA 63 -0.0002

ALA 63 GLU 64 0.0001

GLU 64 PHE 65 0.0002

PHE 65 GLU 66 -0.0003

GLU 66 THR 67 0.0001

THR 67 GLU 68 -0.0003

GLU 68 VAL 69 0.0004

VAL 69 TYR 70 0.0001

TYR 70 ILE 71 -0.0042

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0003

SER 73 PRO 74 0.0000

PRO 74 ARG 75 0.0002

ARG 75 ARG 76 -0.0003

ARG 76 PHE 77 0.0001

PHE 77 SER 78 -0.0000

SER 78 MET 79 0.0001

MET 79 THR 80 0.0001

THR 80 ILE 81 0.0426

ILE 81 PRO 82 0.0002

PRO 82 SER 83 -0.0002

SER 83 GLU 84 0.0001

GLU 84 VAL 85 0.0000

VAL 85 LEU 86 -0.0003

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 0.0001

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 0.0011

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 -0.0002

ARG 94 THR 95 0.0000

THR 95 ARG 96 -0.0000

ARG 96 ILE 97 0.0004

ILE 97 GLN 98 0.0002

GLN 98 ARG 99 -0.0002

ARG 99 GLY 100 -0.0001

GLY 100 LEU 101 -0.0108

LEU 101 ARG 102 0.0004

ARG 102 LEU 125 0.0046

LEU 125 ARG 126 0.0001

ARG 126 GLU 127 -0.0002

GLU 127 ARG 128 -0.0000

ARG 128 TYR 129 -0.0001

TYR 129 ARG 130 0.0002

ARG 130 GLU 131 0.0002

GLU 131 ALA 132 0.0002

ALA 132 MET 133 -0.0002

MET 133 ARG 134 0.0000

ARG 134 ARG 135 -0.0200

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 0.0001

ILE 137 LEU 138 -0.0000

LEU 138 ASP 139 -0.0001

ASP 139 SER 140 0.0001

SER 140 ARG 141 -0.0003

ARG 141 GLU 142 0.0003

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 0.0003

ILE 144 ASP 145 -0.0062

ASP 145 VAL 146 -0.0000

VAL 146 VAL 147 -0.0001

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0000

ALA 150 TYR 151 -0.0002

TYR 151 GLU 152 -0.0001

GLU 152 LEU 153 -0.0002

LEU 153 ASP 154 -0.0000

ASP 154 ALA 155 0.0049

ALA 155 THR 156 0.0001

THR 156 LEU 157 -0.0004

LEU 157 VAL 158 0.0000

VAL 158 SER 159 0.0005

SER 159 ALA 160 -0.0002

ALA 160 ASP 161 -0.0002

ASP 161 GLU 162 0.0001

GLU 162 GLY 163 0.0000

GLY 163 MET 164 0.0001

MET 164 ARG 165 -0.0009

ARG 165 LYS 166 -0.0003

LYS 166 PHE 167 -0.0002

PHE 167 ALA 168 0.0002

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 -0.0002

ARG 170 ILE 171 0.0000

ILE 171 GLY 172 0.0002

GLY 172 ILE 173 -0.0002

ILE 173 LYS 174 0.0000

LYS 174 LEU 175 0.0041

LEU 175 VAL 176 -0.0001

VAL 176 ASN 177 -0.0001

ASN 177 PRO 178 -0.0000

PRO 178 ARG 179 -0.0001

ARG 179 TYR 180 -0.0000

TYR 180 LEU 181 0.0001

LEU 181 ARG 182 -0.0001

ARG 182 GLY 183 0.0003

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 0.0223

MET 185 GLN 186 -0.0000

GLN 186 ASN 187 -0.0004

ASN 187 LEU 188 0.0005

LEU 188 ALA 189 0.0002

ALA 189 SER 1 0.0280

SER 1 ARG 2 0.0000

ARG 2 ARG 3 -0.0000

ARG 3 PHE 4 -0.0002

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 -0.0001

THR 8 SER 9 0.0003

SER 9 VAL 10 -0.0000

VAL 10 PHE 11 0.0021

PHE 11 THR 12 -0.0001

THR 12 ASN 13 -0.0005

ASN 13 PRO 14 0.0000

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 -0.0003

VAL 16 TYR 17 0.0003

TYR 17 LEU 18 -0.0002

LEU 18 ARG 19 -0.0001

ARG 19 PHE 20 -0.0001

PHE 20 ASP 21 0.0026

ASP 21 GLU 22 -0.0002

GLU 22 GLU 23 -0.0001

GLU 23 PRO 24 0.0001

PRO 24 MET 25 0.0002

MET 25 GLN 26 -0.0000

GLN 26 ALA 27 -0.0000

ALA 27 ILE 28 0.0004

ILE 28 SER 29 0.0002

SER 29 VAL 30 -0.0002

VAL 30 PHE 31 0.0028

PHE 31 LEU 32 -0.0002

LEU 32 GLY 33 -0.0003

GLY 33 LEU 34 0.0002

LEU 34 ALA 35 0.0004

ALA 35 ARG 36 -0.0000

ARG 36 ARG 37 -0.0002

ARG 37 ALA 38 -0.0002

ALA 38 ASP 39 0.0002

ASP 39 ALA 40 0.0001

ALA 40 GLU 41 -0.0029

GLU 41 PHE 42 0.0002

PHE 42 TYR 43 0.0003

TYR 43 MET 44 0.0002

MET 44 PRO 45 0.0000

PRO 45 GLY 46 -0.0003

GLY 46 PRO 47 -0.0002

PRO 47 VAL 48 0.0003

VAL 48 TYR 49 -0.0001

TYR 49 GLN 50 0.0002

GLN 50 GLU 51 -0.0067

GLU 51 LEU 52 -0.0003

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 0.0002

ASN 54 LEU 55 0.0002

LEU 55 ARG 56 0.0002

ARG 56 SER 57 -0.0001

SER 57 MET 58 0.0002

MET 58 ASP 59 0.0001

ASP 59 LEU 60 0.0002

LEU 60 ILE 61 -0.0244

ILE 61 GLY 62 -0.0002

GLY 62 ALA 63 0.0004

ALA 63 GLU 64 -0.0001

GLU 64 PHE 65 -0.0003

PHE 65 GLU 66 -0.0000

GLU 66 THR 67 0.0001

THR 67 GLU 68 -0.0003

GLU 68 VAL 69 -0.0003

VAL 69 TYR 70 0.0002

TYR 70 ILE 71 0.0072

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 0.0001

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 0.0004

ARG 75 ARG 76 0.0000

ARG 76 PHE 77 -0.0005

PHE 77 SER 78 -0.0001

SER 78 MET 79 0.0002

MET 79 THR 80 -0.0003

THR 80 ILE 81 -0.0497

ILE 81 PRO 82 -0.0003

PRO 82 SER 83 0.0001

SER 83 GLU 84 0.0004

GLU 84 VAL 85 0.0000

VAL 85 LEU 86 -0.0001

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 -0.0002

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 -0.0030

GLU 91 GLU 92 -0.0002

GLU 92 VAL 93 -0.0000

VAL 93 ARG 94 0.0001

ARG 94 THR 95 0.0000

THR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0004

ILE 97 GLN 98 -0.0001

GLN 98 GLU 131 -0.0007

GLU 131 ALA 132 0.0002

ALA 132 MET 133 -0.0002

MET 133 ARG 134 -0.0002

ARG 134 ARG 135 0.0001

ARG 135 GLY 136 0.0002

GLY 136 ILE 137 -0.0001

ILE 137 LEU 138 0.0002

LEU 138 ASP 139 0.0002

ASP 139 SER 140 -0.0003

SER 140 ARG 141 0.0098

ARG 141 GLU 142 0.0001

GLU 142 ASP 143 0.0002

ASP 143 ILE 144 -0.0002

ILE 144 ASP 145 -0.0000

ASP 145 VAL 146 -0.0001

VAL 146 VAL 147 0.0003

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0000

ALA 150 TYR 151 -0.0027

TYR 151 GLU 152 -0.0001

GLU 152 LEU 153 0.0003

LEU 153 ASP 154 0.0000

ASP 154 ALA 155 -0.0002

ALA 155 THR 156 0.0001

THR 156 LEU 157 0.0000

LEU 157 VAL 158 -0.0001

VAL 158 SER 159 0.0002

SER 159 ALA 160 -0.0004

ALA 160 ASP 161 -0.0051

ASP 161 GLU 162 -0.0002

GLU 162 GLY 163 -0.0002

GLY 163 MET 164 -0.0001

MET 164 ARG 165 0.0001

ARG 165 LYS 166 -0.0001

LYS 166 PHE 167 -0.0003

PHE 167 ALA 168 -0.0002

ALA 168 GLU 169 -0.0002

GLU 169 ARG 170 0.0001

ARG 170 ILE 171 -0.0018

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 -0.0001

ILE 173 LYS 174 0.0002

LYS 174 LEU 175 -0.0000

LEU 175 VAL 176 0.0002

VAL 176 ASN 177 0.0000

ASN 177 PRO 178 -0.0001

PRO 178 ARG 179 0.0001

ARG 179 TYR 180 -0.0004

TYR 180 LEU 181 -0.0069

LEU 181 ARG 182 -0.0002

ARG 182 GLY 183 -0.0005

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 0.0002

MET 185 GLN 186 -0.0003

GLN 186 ASN 187 -0.0000

ASN 187 LEU 188 0.0005

LEU 188 ALA 189 0.0004

ALA 189 SER 1 -0.0193

SER 1 ARG 2 -0.0002

ARG 2 ARG 3 0.0003

ARG 3 PHE 4 0.0003

PHE 4 VAL 5 -0.0001

VAL 5 LEU 6 -0.0000

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 0.0002

THR 8 SER 9 0.0004

SER 9 VAL 10 -0.0000

VAL 10 PHE 11 0.0222

PHE 11 THR 12 -0.0001

THR 12 ASN 13 0.0000

ASN 13 PRO 14 -0.0003

PRO 14 ASP 15 0.0000

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 -0.0001

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 0.0003

ARG 19 PHE 20 -0.0003

PHE 20 ASP 21 0.0023

ASP 21 GLU 22 0.0003

GLU 22 GLU 23 0.0004

GLU 23 PRO 24 0.0000

PRO 24 MET 25 0.0000

MET 25 GLN 26 -0.0000

GLN 26 ALA 27 0.0002

ALA 27 ILE 28 -0.0001

ILE 28 SER 29 0.0002

SER 29 VAL 30 -0.0003

VAL 30 PHE 31 -0.0134

PHE 31 LEU 32 -0.0003

LEU 32 GLY 33 -0.0001

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 0.0002

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 -0.0004

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 -0.0000

ASP 39 ALA 40 0.0001

ALA 40 GLU 41 -0.0000

GLU 41 PHE 42 -0.0004

PHE 42 TYR 43 -0.0000

TYR 43 MET 44 0.0005

MET 44 PRO 45 -0.0003

PRO 45 GLY 46 -0.0004

GLY 46 PRO 47 0.0001

PRO 47 VAL 48 0.0002

VAL 48 TYR 49 -0.0005

TYR 49 GLN 50 -0.0000

GLN 50 GLU 51 -0.0194

GLU 51 LEU 52 0.0002

LEU 52 CYS 53 0.0004

CYS 53 ASN 54 -0.0002

ASN 54 LEU 55 0.0001

LEU 55 ARG 56 -0.0000

ARG 56 SER 57 -0.0001

SER 57 MET 58 -0.0003

MET 58 ASP 59 0.0002

ASP 59 LEU 60 0.0003

LEU 60 ILE 61 -0.0110

ILE 61 GLY 62 -0.0001

GLY 62 ALA 63 0.0005

ALA 63 GLU 64 -0.0002

GLU 64 PHE 65 -0.0005

PHE 65 GLU 66 0.0000

GLU 66 THR 67 0.0003

THR 67 GLU 68 0.0001

GLU 68 VAL 69 -0.0002

VAL 69 TYR 70 0.0003

TYR 70 ILE 71 0.0167

ILE 71 ARG 72 0.0002

ARG 72 SER 73 -0.0001

SER 73 PRO 74 0.0000

PRO 74 ARG 75 -0.0001

ARG 75 ARG 76 0.0003

ARG 76 PHE 77 -0.0000

PHE 77 SER 78 0.0002

SER 78 MET 79 -0.0000

MET 79 THR 80 -0.0001

THR 80 ILE 81 -0.0642

ILE 81 PRO 82 0.0002

PRO 82 SER 83 -0.0004

SER 83 GLU 84 0.0000

GLU 84 VAL 85 0.0002

VAL 85 LEU 86 -0.0001

LEU 86 TYR 87 -0.0000

TYR 87 GLU 88 -0.0000

GLU 88 PHE 89 0.0001

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 0.0092

GLU 91 GLU 92 -0.0004

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 -0.0003

ARG 94 THR 95 -0.0005

THR 95 ARG 96 -0.0001

ARG 96 ILE 97 -0.0001

ILE 97 GLN 98 0.0003

GLN 98 GLU 131 -0.0056

GLU 131 ALA 132 0.0004

ALA 132 MET 133 0.0001

MET 133 ARG 134 -0.0002

ARG 134 ARG 135 -0.0000

ARG 135 GLY 136 0.0002

GLY 136 ILE 137 -0.0002

ILE 137 LEU 138 -0.0002

LEU 138 ASP 139 0.0000

ASP 139 SER 140 -0.0002

SER 140 ARG 141 -0.0023

ARG 141 GLU 142 0.0003

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 -0.0000

ILE 144 ASP 145 0.0000

ASP 145 VAL 146 0.0004

VAL 146 VAL 147 -0.0004

VAL 147 LEU 148 -0.0002

LEU 148 LEU 149 0.0001

LEU 149 ALA 150 0.0001

ALA 150 TYR 151 0.0066

TYR 151 GLU 152 -0.0001

GLU 152 LEU 153 0.0002

LEU 153 ASP 154 0.0001

ASP 154 ALA 155 -0.0001

ALA 155 THR 156 0.0003

THR 156 LEU 157 -0.0002

LEU 157 VAL 158 -0.0004

VAL 158 SER 159 -0.0001

SER 159 ALA 160 0.0003

ALA 160 ASP 161 0.0280

ASP 161 GLU 162 -0.0003

GLU 162 GLY 163 -0.0000

GLY 163 MET 164 -0.0003

MET 164 ARG 165 -0.0005

ARG 165 LYS 166 -0.0004

LYS 166 PHE 167 -0.0001

PHE 167 ALA 168 0.0001

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 -0.0001

ARG 170 ILE 171 -0.0176

ILE 171 GLY 172 0.0002

GLY 172 ILE 173 0.0001

ILE 173 LYS 174 -0.0000

LYS 174 LEU 175 -0.0000

LEU 175 VAL 176 -0.0002

VAL 176 ASN 177 -0.0001

ASN 177 PRO 178 0.0000

PRO 178 ARG 179 -0.0001

ARG 179 TYR 180 0.0000

TYR 180 LEU 181 0.0014

LEU 181 ARG 182 0.0002

ARG 182 GLY 183 0.0003

GLY 183 VAL 184 -0.0002

VAL 184 MET 185 0.0002

MET 185 GLN 186 0.0001

GLN 186 ASN 187 0.0003

ASN 187 LEU 188 -0.0002

LEU 188 ALA 189 -0.0002

ALA 189 SER 1 -0.0257

SER 1 ARG 2 0.0006

ARG 2 ARG 3 -0.0001

ARG 3 PHE 4 0.0001

PHE 4 VAL 5 -0.0003

VAL 5 LEU 6 0.0004

LEU 6 ASP 7 0.0001

ASP 7 THR 8 -0.0002

THR 8 SER 9 -0.0005

SER 9 VAL 10 0.0002

VAL 10 PHE 11 0.0001

PHE 11 THR 12 0.0001

THR 12 ASN 13 0.0000

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 0.0005

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 -0.0002

TYR 17 LEU 18 0.0002

LEU 18 ARG 19 -0.0002

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 -0.0070

ASP 21 GLU 22 0.0003

GLU 22 GLU 23 0.0003

GLU 23 PRO 24 -0.0002

PRO 24 MET 25 0.0001

MET 25 GLN 26 0.0000

GLN 26 ALA 27 -0.0001

ALA 27 ILE 28 0.0000

ILE 28 SER 29 -0.0001

SER 29 VAL 30 0.0002

VAL 30 PHE 31 -0.0024

PHE 31 LEU 32 0.0001

LEU 32 GLY 33 0.0000

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 0.0002

ALA 35 ARG 36 -0.0001

ARG 36 ARG 37 -0.0001

ARG 37 ALA 38 -0.0002

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 0.0003

ALA 40 GLU 41 0.0386

GLU 41 PHE 42 -0.0002

PHE 42 TYR 43 0.0001

TYR 43 MET 44 -0.0001

MET 44 PRO 45 -0.0001

PRO 45 GLY 46 0.0001

GLY 46 PRO 47 0.0002

PRO 47 VAL 48 0.0001

VAL 48 TYR 49 -0.0000

TYR 49 GLN 50 -0.0003

GLN 50 GLU 51 -0.0286

GLU 51 LEU 52 -0.0002

LEU 52 CYS 53 0.0001

CYS 53 ASN 54 -0.0002

ASN 54 LEU 55 -0.0001

LEU 55 ARG 56 -0.0003

ARG 56 SER 57 0.0002

SER 57 MET 58 -0.0001

MET 58 ASP 59 -0.0001

ASP 59 LEU 60 -0.0002

LEU 60 ILE 61 -0.0198

ILE 61 GLY 62 0.0003

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 0.0002

GLU 64 PHE 65 -0.0003

PHE 65 GLU 66 0.0001

GLU 66 THR 67 0.0002

THR 67 GLU 68 -0.0001

GLU 68 VAL 69 0.0000

VAL 69 TYR 70 0.0000

TYR 70 ILE 71 0.0152

ILE 71 ARG 72 0.0003

ARG 72 SER 73 0.0002

SER 73 PRO 74 0.0001

PRO 74 ARG 75 -0.0001

ARG 75 ARG 76 0.0003

ARG 76 PHE 77 0.0001

PHE 77 SER 78 -0.0000

SER 78 MET 79 0.0003

MET 79 THR 80 -0.0001

THR 80 ILE 81 0.0008

ILE 81 PRO 82 0.0002

PRO 82 SER 83 0.0000

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 0.0002

VAL 85 LEU 86 -0.0002

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 0.0004

GLU 88 PHE 89 -0.0003

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 -0.0060

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 0.0005

VAL 93 ARG 94 0.0002

ARG 94 THR 95 -0.0004

THR 95 ARG 96 0.0000

ARG 96 ILE 97 -0.0002

ILE 97 GLN 98 0.0002

GLN 98 GLU 131 -0.0004

GLU 131 ALA 132 -0.0001

ALA 132 MET 133 0.0001

MET 133 ARG 134 0.0000

ARG 134 ARG 135 -0.0003

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 -0.0004

ILE 137 LEU 138 0.0002

LEU 138 ASP 139 -0.0000

ASP 139 SER 140 -0.0002

SER 140 ARG 141 -0.0006

ARG 141 GLU 142 -0.0002

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 0.0003

ILE 144 ASP 145 0.0000

ASP 145 VAL 146 0.0004

VAL 146 VAL 147 0.0005

VAL 147 LEU 148 -0.0002

LEU 148 LEU 149 0.0000

LEU 149 ALA 150 0.0001

ALA 150 TYR 151 -0.0066

TYR 151 GLU 152 0.0001

GLU 152 LEU 153 0.0004

LEU 153 ASP 154 -0.0002

ASP 154 ALA 155 0.0003

ALA 155 THR 156 -0.0003

THR 156 LEU 157 -0.0001

LEU 157 VAL 158 0.0001

VAL 158 SER 159 -0.0000

SER 159 ALA 160 -0.0000

ALA 160 ASP 161 0.0073

ASP 161 GLU 162 0.0002

GLU 162 GLY 163 -0.0000

GLY 163 MET 164 0.0001

MET 164 ARG 165 -0.0002

ARG 165 LYS 166 -0.0002

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 0.0001

ALA 168 GLU 169 0.0000

GLU 169 ARG 170 -0.0004

ARG 170 ILE 171 0.0118

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 0.0004

LYS 174 LEU 175 -0.0000

LEU 175 VAL 176 -0.0000

VAL 176 ASN 177 0.0001

ASN 177 PRO 178 -0.0002

PRO 178 ARG 179 -0.0003

ARG 179 TYR 180 -0.0002

TYR 180 LEU 181 0.0136

LEU 181 ARG 182 0.0001

ARG 182 GLY 183 -0.0001

GLY 183 VAL 184 -0.0000

VAL 184 MET 185 -0.0000

MET 185 GLN 186 -0.0001

GLN 186 ASN 187 -0.0000

ASN 187 LEU 188 0.0000

LEU 188 ALA 189 0.0002

ALA 189 ARG 2 0.0177

ARG 2 ARG 3 0.0000

ARG 3 PHE 4 0.0001

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 -0.0000

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0002

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0001

VAL 10 PHE 11 0.0004

PHE 11 THR 12 0.0140

THR 12 ASN 13 0.0000

ASN 13 PRO 14 0.0000

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 -0.0002

VAL 16 TYR 17 -0.0001

TYR 17 LEU 18 -0.0004

LEU 18 ARG 19 -0.0001

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 0.0000

ASP 21 GLU 22 -0.0054

GLU 22 GLU 23 0.0001

GLU 23 PRO 24 0.0002

PRO 24 MET 25 0.0001

MET 25 GLN 26 0.0001

GLN 26 ALA 27 -0.0001

ALA 27 ILE 28 0.0004

ILE 28 SER 29 -0.0000

SER 29 VAL 30 -0.0001

VAL 30 PHE 31 0.0001

PHE 31 LEU 32 -0.0013

LEU 32 GLY 33 -0.0000

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 0.0001

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 0.0002

ARG 37 ALA 38 0.0002

ALA 38 ASP 39 -0.0004

ASP 39 ALA 40 0.0003

ALA 40 GLU 41 0.0002

GLU 41 PHE 42 -0.0352

PHE 42 TYR 43 0.0001

TYR 43 MET 44 -0.0002

MET 44 PRO 45 0.0003

PRO 45 GLY 46 0.0002

GLY 46 PRO 47 -0.0001

PRO 47 VAL 48 0.0003

VAL 48 TYR 49 0.0001

TYR 49 GLN 50 0.0003

GLN 50 GLU 51 0.0000

GLU 51 LEU 52 0.0004

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 0.0002

ASN 54 LEU 55 -0.0002

LEU 55 ARG 56 0.0003

ARG 56 SER 57 0.0002

SER 57 MET 58 0.0000

MET 58 ASP 59 -0.0000

ASP 59 LEU 60 -0.0000

LEU 60 ILE 61 0.0002

ILE 61 GLY 62 0.0081

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 0.0002

GLU 64 PHE 65 -0.0001

PHE 65 GLU 66 0.0003

GLU 66 THR 67 -0.0001

THR 67 GLU 68 0.0003

GLU 68 VAL 69 0.0001

VAL 69 TYR 70 -0.0004

TYR 70 ILE 71 0.0001

ILE 71 ARG 72 -0.0041

ARG 72 SER 73 -0.0004

SER 73 PRO 74 0.0001

PRO 74 ARG 75 0.0001

ARG 75 ARG 76 -0.0001

ARG 76 PHE 77 -0.0001

PHE 77 SER 78 -0.0003

SER 78 MET 79 0.0003

MET 79 THR 80 0.0001

THR 80 ILE 81 -0.0000

ILE 81 PRO 82 0.0436

PRO 82 SER 83 -0.0003

SER 83 GLU 84 -0.0005

GLU 84 VAL 85 -0.0001

VAL 85 LEU 86 0.0001

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 -0.0000

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 0.0001

GLU 91 GLU 92 -0.0079

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 -0.0003

ARG 94 THR 95 -0.0003

THR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0000

ILE 97 GLN 98 0.0001

GLN 98 GLU 131 0.0009

GLU 131 ALA 132 0.0001

ALA 132 MET 133 -0.0003

MET 133 ARG 134 0.0004

ARG 134 ARG 135 -0.0000

ARG 135 GLY 136 0.0002

GLY 136 ILE 137 -0.0003

ILE 137 LEU 138 0.0003

LEU 138 ASP 139 -0.0002

ASP 139 SER 140 0.0004

SER 140 ARG 141 0.0027

ARG 141 GLU 142 0.0001

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 -0.0003

ILE 144 ASP 145 0.0001

ASP 145 VAL 146 0.0001

VAL 146 VAL 147 -0.0003

VAL 147 LEU 148 -0.0004

LEU 148 LEU 149 0.0004

LEU 149 ALA 150 0.0002

ALA 150 TYR 151 -0.0036

TYR 151 GLU 152 -0.0002

GLU 152 LEU 153 0.0001

LEU 153 ASP 154 -0.0002

ASP 154 ALA 155 -0.0003

ALA 155 THR 156 -0.0002

THR 156 LEU 157 -0.0000

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 -0.0002

SER 159 ALA 160 0.0001

ALA 160 ASP 161 -0.0285

ASP 161 GLU 162 0.0001

GLU 162 GLY 163 0.0001

GLY 163 MET 164 0.0004

MET 164 ARG 165 -0.0000

ARG 165 LYS 166 0.0003

LYS 166 PHE 167 -0.0000

PHE 167 ALA 168 -0.0002

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 -0.0000

ARG 170 ILE 171 -0.0088

ILE 171 GLY 172 -0.0003

GLY 172 ILE 173 0.0003

ILE 173 LYS 174 -0.0000

LYS 174 LEU 175 0.0000

LEU 175 VAL 176 -0.0000

VAL 176 ASN 177 -0.0003

ASN 177 PRO 178 0.0000

PRO 178 ARG 179 0.0001

ARG 179 TYR 180 -0.0001

TYR 180 LEU 181 0.0092

LEU 181 ARG 182 0.0000

ARG 182 GLY 183 0.0001

GLY 183 VAL 184 0.0003

VAL 184 MET 185 0.0001

MET 185 GLN 186 -0.0003

GLN 186 ASN 187 0.0005

ASN 187 LEU 188 0.0001

LEU 188 ALA 189 -0.0001

ALA 189 SER 1 -0.0054

SER 1 ARG 2 0.0000

ARG 2 ARG 3 -0.0005

ARG 3 PHE 4 0.0000

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 0.0000

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 0.0001

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0001

VAL 10 PHE 11 -0.0017

PHE 11 THR 12 0.0001

THR 12 ASN 13 0.0002

ASN 13 PRO 14 0.0004

PRO 14 ASP 15 -0.0000

ASP 15 VAL 16 0.0004

VAL 16 TYR 17 -0.0002

TYR 17 LEU 18 -0.0000

LEU 18 ARG 19 -0.0002

ARG 19 PHE 20 -0.0003

PHE 20 ASP 21 -0.0057

ASP 21 GLU 22 -0.0001

GLU 22 GLU 23 0.0003

GLU 23 PRO 24 0.0000

PRO 24 MET 25 0.0006

MET 25 GLN 26 -0.0002

GLN 26 ALA 27 -0.0002

ALA 27 ILE 28 -0.0001

ILE 28 SER 29 -0.0000

SER 29 VAL 30 0.0000

VAL 30 PHE 31 -0.0065

PHE 31 LEU 32 0.0000

LEU 32 GLY 33 0.0002

GLY 33 LEU 34 0.0005

LEU 34 ALA 35 -0.0002

ALA 35 ARG 36 -0.0000

ARG 36 ARG 37 0.0001

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 -0.0001

ALA 40 GLU 41 0.0244

GLU 41 PHE 42 -0.0002

PHE 42 TYR 43 0.0001

TYR 43 MET 44 0.0005

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0000

GLY 46 PRO 47 -0.0003

PRO 47 VAL 48 0.0000

VAL 48 TYR 49 -0.0001

TYR 49 GLN 50 0.0002

GLN 50 GLU 51 -0.0055

GLU 51 LEU 52 -0.0001

LEU 52 CYS 53 0.0001

CYS 53 ASN 54 0.0001

ASN 54 LEU 55 -0.0003

LEU 55 ARG 56 -0.0003

ARG 56 SER 57 -0.0002

SER 57 MET 58 0.0004

MET 58 ASP 59 0.0002

ASP 59 LEU 60 -0.0001

LEU 60 ILE 61 -0.0161

ILE 61 GLY 62 -0.0002

GLY 62 ALA 63 -0.0000

ALA 63 GLU 64 -0.0000

GLU 64 PHE 65 0.0001

PHE 65 GLU 66 0.0000

GLU 66 THR 67 -0.0003

THR 67 GLU 68 0.0002

GLU 68 VAL 69 0.0001

VAL 69 TYR 70 -0.0006

TYR 70 ILE 71 0.0107

ILE 71 ARG 72 -0.0000

ARG 72 SER 73 -0.0005

SER 73 PRO 74 0.0003

PRO 74 ARG 75 -0.0003

ARG 75 ARG 76 -0.0003

ARG 76 PHE 77 -0.0001

PHE 77 SER 78 -0.0001

SER 78 MET 79 -0.0001

MET 79 THR 80 0.0000

THR 80 ILE 81 -0.0056

ILE 81 PRO 82 0.0005

PRO 82 SER 83 0.0001

SER 83 GLU 84 0.0000

GLU 84 VAL 85 0.0000

VAL 85 LEU 86 0.0004

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 0.0002

GLU 88 PHE 89 0.0002

PHE 89 ILE 90 0.0002

ILE 90 GLU 91 -0.0055

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 0.0000

VAL 93 ARG 94 0.0000

ARG 94 THR 95 0.0002

THR 95 ARG 96 -0.0001

ARG 96 ILE 97 -0.0002

ILE 97 GLN 98 0.0001

GLN 98 GLU 131 0.0003

GLU 131 ALA 132 0.0001

ALA 132 MET 133 0.0004

MET 133 ARG 134 0.0002

ARG 134 ARG 135 0.0003

ARG 135 GLY 136 -0.0000

GLY 136 ILE 137 0.0000

ILE 137 LEU 138 -0.0001

LEU 138 ASP 139 0.0002

ASP 139 SER 140 0.0003

SER 140 ARG 141 0.0108

ARG 141 GLU 142 -0.0005

GLU 142 ASP 143 0.0004

ASP 143 ILE 144 0.0001

ILE 144 ASP 145 -0.0000

ASP 145 VAL 146 0.0001

VAL 146 VAL 147 0.0001

VAL 147 LEU 148 0.0002

LEU 148 LEU 149 -0.0000

LEU 149 ALA 150 -0.0001

ALA 150 TYR 151 -0.0061

TYR 151 GLU 152 0.0004

GLU 152 LEU 153 -0.0000

LEU 153 ASP 154 0.0001

ASP 154 ALA 155 -0.0000

ALA 155 THR 156 0.0002

THR 156 LEU 157 -0.0001

LEU 157 VAL 158 0.0000

VAL 158 SER 159 0.0003

SER 159 ALA 160 0.0003

ALA 160 ASP 161 -0.0046

ASP 161 GLU 162 -0.0002

GLU 162 GLY 163 -0.0000

GLY 163 MET 164 -0.0002

MET 164 ARG 165 -0.0001

ARG 165 LYS 166 0.0003

LYS 166 PHE 167 -0.0001

PHE 167 ALA 168 -0.0001

ALA 168 GLU 169 -0.0002

GLU 169 ARG 170 0.0001

ARG 170 ILE 171 0.0115

ILE 171 GLY 172 -0.0003

GLY 172 ILE 173 0.0004

ILE 173 LYS 174 -0.0002

LYS 174 LEU 175 -0.0002

LEU 175 VAL 176 0.0001

VAL 176 ASN 177 0.0002

ASN 177 PRO 178 0.0003

PRO 178 ARG 179 0.0004

ARG 179 TYR 180 -0.0002

TYR 180 LEU 181 0.0178

LEU 181 ARG 182 0.0000

ARG 182 GLY 183 0.0001

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 0.0002

MET 185 GLN 186 -0.0000

GLN 186 ASN 187 -0.0001

ASN 187 LEU 188 -0.0004

LEU 188 ALA 189 0.0002

ALA 189 SER 1 -0.0407

SER 1 ARG 2 -0.0002

ARG 2 ARG 3 0.0001

ARG 3 PHE 4 0.0003

PHE 4 VAL 5 0.0000

VAL 5 LEU 6 0.0002

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 0.0004

THR 8 SER 9 0.0001

SER 9 VAL 10 0.0001

VAL 10 PHE 11 0.0056

PHE 11 THR 12 -0.0001

THR 12 ASN 13 0.0002

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0003

TYR 17 LEU 18 -0.0002

LEU 18 ARG 19 -0.0002

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 0.0106

ASP 21 GLU 22 -0.0002

GLU 22 GLU 23 0.0001

GLU 23 PRO 24 -0.0001

PRO 24 MET 25 0.0001

MET 25 GLN 26 -0.0000

GLN 26 ALA 27 0.0000

ALA 27 ILE 28 -0.0002

ILE 28 SER 29 0.0000

SER 29 VAL 30 0.0002

VAL 30 PHE 31 0.0036

PHE 31 LEU 32 -0.0002

LEU 32 GLY 33 0.0001

GLY 33 LEU 34 -0.0002

LEU 34 ALA 35 -0.0003

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 0.0004

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 -0.0000

ASP 39 ALA 40 -0.0003

ALA 40 GLU 41 -0.0149

GLU 41 PHE 42 0.0001

PHE 42 TYR 43 -0.0000

TYR 43 MET 44 -0.0001

MET 44 PRO 45 0.0000

PRO 45 GLY 46 0.0002

GLY 46 PRO 47 0.0004

PRO 47 VAL 48 0.0001

VAL 48 TYR 49 -0.0001

TYR 49 GLN 50 -0.0001

GLN 50 GLU 51 0.0051

GLU 51 LEU 52 -0.0000

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 0.0001

ASN 54 LEU 55 0.0002

LEU 55 ARG 56 -0.0002

ARG 56 SER 57 0.0003

SER 57 MET 58 0.0005

MET 58 ASP 59 -0.0003

ASP 59 LEU 60 0.0003

LEU 60 ILE 61 -0.0136

ILE 61 GLY 62 -0.0002

GLY 62 ALA 63 0.0002

ALA 63 GLU 64 0.0004

GLU 64 PHE 65 -0.0003

PHE 65 GLU 66 -0.0003

GLU 66 THR 67 -0.0001

THR 67 GLU 68 0.0003

GLU 68 VAL 69 -0.0001

VAL 69 TYR 70 0.0001

TYR 70 ILE 71 0.0063

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0001

SER 73 PRO 74 0.0001

PRO 74 ARG 75 -0.0001

ARG 75 ARG 76 0.0001

ARG 76 PHE 77 -0.0002

PHE 77 SER 78 0.0002

SER 78 MET 79 0.0001

MET 79 THR 80 0.0000

THR 80 ILE 81 -0.0377

ILE 81 PRO 82 0.0001

PRO 82 SER 83 -0.0000

SER 83 GLU 84 0.0001

GLU 84 VAL 85 0.0003

VAL 85 LEU 86 -0.0002

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 -0.0003

GLU 88 PHE 89 0.0002

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 0.0023

GLU 91 GLU 92 0.0003

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 0.0000

ARG 94 THR 95 -0.0004

THR 95 ARG 96 0.0004

ARG 96 ILE 97 0.0001

ILE 97 GLN 98 -0.0004

GLN 98 GLU 131 -0.0191

GLU 131 ALA 132 -0.0000

ALA 132 MET 133 0.0006

MET 133 ARG 134 -0.0002

ARG 134 ARG 135 -0.0002

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 -0.0002

ILE 137 LEU 138 0.0001

LEU 138 ASP 139 -0.0001

ASP 139 SER 140 0.0004

SER 140 ARG 141 0.0140

ARG 141 GLU 142 0.0003

GLU 142 ASP 143 -0.0001

ASP 143 ILE 144 0.0000

ILE 144 ASP 145 0.0001

ASP 145 VAL 146 -0.0000

VAL 146 VAL 147 -0.0002

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 0.0001

LEU 149 ALA 150 0.0003

ALA 150 TYR 151 0.0029

TYR 151 GLU 152 0.0004

GLU 152 LEU 153 -0.0002

LEU 153 ASP 154 -0.0004

ASP 154 ALA 155 0.0002

ALA 155 THR 156 -0.0002

THR 156 LEU 157 -0.0001

LEU 157 VAL 158 -0.0000

VAL 158 SER 159 0.0002

SER 159 ALA 160 0.0000

ALA 160 ASP 161 0.0142

ASP 161 GLU 162 -0.0004

GLU 162 GLY 163 0.0002

GLY 163 MET 164 -0.0001

MET 164 ARG 165 -0.0003

ARG 165 LYS 166 0.0000

LYS 166 PHE 167 -0.0002

PHE 167 ALA 168 0.0002

ALA 168 GLU 169 0.0003

GLU 169 ARG 170 0.0002

ARG 170 ILE 171 -0.0108

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0001

ILE 173 LYS 174 -0.0002

LYS 174 LEU 175 -0.0002

LEU 175 VAL 176 0.0002

VAL 176 ASN 177 -0.0003

ASN 177 PRO 178 -0.0003

PRO 178 ARG 179 0.0001

ARG 179 TYR 180 -0.0001

TYR 180 LEU 181 -0.0180

LEU 181 ARG 182 0.0001

ARG 182 GLY 183 0.0001

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 0.0001

MET 185 GLN 186 -0.0001

GLN 186 ASN 187 -0.0003

ASN 187 LEU 188 0.0000

LEU 188 ALA 189 -0.0001

ALA 189 SER 1 -0.0343

SER 1 ARG 2 0.0001

ARG 2 ARG 3 0.0003

ARG 3 PHE 4 -0.0001

PHE 4 VAL 5 0.0005

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 -0.0000

THR 8 SER 9 0.0000

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 -0.0032

PHE 11 THR 12 -0.0003

THR 12 ASN 13 0.0004

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 -0.0000

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0003

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 -0.0000

ARG 19 PHE 20 -0.0001

PHE 20 ASP 21 -0.0042

ASP 21 GLU 22 0.0002

GLU 22 GLU 23 0.0002

GLU 23 PRO 24 0.0005

PRO 24 MET 25 -0.0001

MET 25 GLN 26 0.0001

GLN 26 ALA 27 0.0002

ALA 27 ILE 28 -0.0002

ILE 28 SER 29 0.0001

SER 29 VAL 30 -0.0003

VAL 30 PHE 31 -0.0028

PHE 31 LEU 32 -0.0003

LEU 32 GLY 33 -0.0000

GLY 33 LEU 34 0.0005

LEU 34 ALA 35 -0.0001

ALA 35 ARG 36 0.0001

ARG 36 ARG 37 0.0005

ARG 37 ALA 38 0.0001

ALA 38 ASP 39 0.0000

ASP 39 ALA 40 -0.0001

ALA 40 GLU 41 0.0073

GLU 41 PHE 42 -0.0003

PHE 42 TYR 43 0.0003

TYR 43 MET 44 -0.0004

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0004

GLY 46 PRO 47 -0.0001

PRO 47 VAL 48 -0.0000

VAL 48 TYR 49 0.0000

TYR 49 GLN 50 -0.0000

GLN 50 GLU 51 0.0013

GLU 51 LEU 52 0.0002

LEU 52 CYS 53 0.0003

CYS 53 ASN 54 -0.0001

ASN 54 LEU 55 0.0001

LEU 55 ARG 56 -0.0000

ARG 56 SER 57 -0.0001

SER 57 MET 58 -0.0001

MET 58 ASP 59 -0.0002

ASP 59 LEU 60 -0.0002

LEU 60 ILE 61 0.0199

ILE 61 GLY 62 -0.0004

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 0.0003

GLU 64 PHE 65 0.0003

PHE 65 GLU 66 0.0002

GLU 66 THR 67 0.0002

THR 67 GLU 68 -0.0002

GLU 68 VAL 69 0.0000

VAL 69 TYR 70 -0.0002

TYR 70 ILE 71 -0.0079

ILE 71 ARG 72 0.0000

ARG 72 SER 73 0.0001

SER 73 PRO 74 0.0000

PRO 74 ARG 75 0.0002

ARG 75 ARG 76 -0.0000

ARG 76 PHE 77 0.0003

PHE 77 SER 78 -0.0001

SER 78 MET 79 0.0000

MET 79 THR 80 0.0002

THR 80 ILE 81 0.0534

ILE 81 PRO 82 0.0001

PRO 82 SER 83 0.0002

SER 83 GLU 84 0.0000

GLU 84 VAL 85 0.0000

VAL 85 LEU 86 0.0000

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 0.0003

GLU 88 PHE 89 0.0002

PHE 89 ILE 90 0.0000

ILE 90 GLU 91 0.0014

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 0.0004

ARG 94 THR 95 0.0002

THR 95 ARG 96 -0.0004

ARG 96 ILE 97 -0.0001

ILE 97 GLN 98 -0.0003

GLN 98 GLU 131 0.0006

GLU 131 ALA 132 -0.0002

ALA 132 MET 133 0.0001

MET 133 ARG 134 -0.0000

ARG 134 ARG 135 0.0002

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 0.0002

ILE 137 LEU 138 0.0003

LEU 138 ASP 139 -0.0003

ASP 139 SER 140 0.0004

SER 140 ARG 141 -0.0108

ARG 141 GLU 142 0.0003

GLU 142 ASP 143 -0.0004

ASP 143 ILE 144 -0.0000

ILE 144 ASP 145 0.0002

ASP 145 VAL 146 -0.0001

VAL 146 VAL 147 0.0003

VAL 147 LEU 148 0.0002

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0000

ALA 150 TYR 151 0.0027

TYR 151 GLU 152 -0.0001

GLU 152 LEU 153 0.0001

LEU 153 ASP 154 0.0003

ASP 154 ALA 155 -0.0000

ALA 155 THR 156 0.0000

THR 156 LEU 157 0.0002

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 0.0004

SER 159 ALA 160 -0.0000

ALA 160 ASP 161 0.0064

ASP 161 GLU 162 0.0001

GLU 162 GLY 163 -0.0006

GLY 163 MET 164 0.0003

MET 164 ARG 165 0.0002

ARG 165 LYS 166 0.0002

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 0.0003

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 -0.0000

ARG 170 ILE 171 0.0027

ILE 171 GLY 172 -0.0000

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 0.0001

LYS 174 LEU 175 0.0002

LEU 175 VAL 176 -0.0001

VAL 176 ASN 177 -0.0000

ASN 177 PRO 178 -0.0003

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 0.0002

TYR 180 LEU 181 0.0095

LEU 181 ARG 182 -0.0002

ARG 182 GLY 183 0.0001

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 0.0001

MET 185 GLN 186 0.0000

GLN 186 ASN 187 -0.0002

ASN 187 LEU 188 -0.0002

LEU 188 ALA 189 0.0001

ALA 189 SER 1 0.0281

SER 1 ARG 2 0.0003

ARG 2 ARG 3 -0.0002

ARG 3 PHE 4 0.0002

PHE 4 VAL 5 -0.0003

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 0.0000

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0001

SER 9 VAL 10 -0.0000

VAL 10 PHE 11 -0.0225

PHE 11 THR 12 -0.0002

THR 12 ASN 13 0.0001

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0001

TYR 17 LEU 18 0.0002

LEU 18 ARG 19 -0.0005

ARG 19 PHE 20 -0.0001

PHE 20 ASP 21 -0.0020

ASP 21 GLU 22 0.0000

GLU 22 GLU 23 -0.0002

GLU 23 PRO 24 0.0002

PRO 24 MET 25 -0.0000

MET 25 GLN 26 -0.0001

GLN 26 ALA 27 0.0000

ALA 27 ILE 28 -0.0001

ILE 28 SER 29 -0.0000

SER 29 VAL 30 0.0002

VAL 30 PHE 31 0.0131

PHE 31 LEU 32 -0.0004

LEU 32 GLY 33 -0.0003

GLY 33 LEU 34 -0.0002

LEU 34 ALA 35 0.0000

ALA 35 ARG 36 -0.0003

ARG 36 ARG 37 -0.0002

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 0.0002

ASP 39 ALA 40 -0.0004

ALA 40 GLU 41 0.0002

GLU 41 PHE 42 -0.0005

PHE 42 TYR 43 0.0000

TYR 43 MET 44 0.0002

MET 44 PRO 45 0.0002

PRO 45 GLY 46 -0.0002

GLY 46 PRO 47 0.0000

PRO 47 VAL 48 -0.0001

VAL 48 TYR 49 0.0005

TYR 49 GLN 50 0.0001

GLN 50 GLU 51 0.0064

GLU 51 LEU 52 -0.0001

LEU 52 CYS 53 0.0001

CYS 53 ASN 54 -0.0002

ASN 54 LEU 55 0.0002

LEU 55 ARG 56 -0.0003

ARG 56 SER 57 -0.0001

SER 57 MET 58 -0.0000

MET 58 ASP 59 0.0004

ASP 59 LEU 60 -0.0002

LEU 60 ILE 61 0.0139

ILE 61 GLY 62 0.0001

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 -0.0001

GLU 64 PHE 65 0.0004

PHE 65 GLU 66 -0.0001

GLU 66 THR 67 0.0002

THR 67 GLU 68 0.0000

GLU 68 VAL 69 0.0003

VAL 69 TYR 70 0.0005

TYR 70 ILE 71 0.0018

ILE 71 ARG 72 0.0001

ARG 72 SER 73 0.0000

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 -0.0003

ARG 75 ARG 76 0.0002

ARG 76 PHE 77 -0.0001

PHE 77 SER 78 -0.0000

SER 78 MET 79 0.0001

MET 79 THR 80 -0.0001

THR 80 ILE 81 0.0563

ILE 81 PRO 82 0.0001

PRO 82 SER 83 -0.0000

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 -0.0001

VAL 85 LEU 86 -0.0003

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 0.0000

PHE 89 ILE 90 -0.0003

ILE 90 GLU 91 -0.0018

GLU 91 GLU 92 -0.0002

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 -0.0002

ARG 94 THR 95 -0.0000

THR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0002

ILE 97 GLN 98 0.0000

GLN 98 GLU 131 -0.0055

GLU 131 ALA 132 -0.0000

ALA 132 MET 133 0.0003

MET 133 ARG 134 -0.0000

ARG 134 ARG 135 -0.0002

ARG 135 GLY 136 -0.0000

GLY 136 ILE 137 -0.0001

ILE 137 LEU 138 0.0001

LEU 138 ASP 139 0.0003

ASP 139 SER 140 -0.0001

SER 140 ARG 141 0.0069

ARG 141 GLU 142 -0.0002

GLU 142 ASP 143 -0.0002

ASP 143 ILE 144 -0.0000

ILE 144 ASP 145 -0.0000

ASP 145 VAL 146 0.0001

VAL 146 VAL 147 -0.0000

VAL 147 LEU 148 -0.0002

LEU 148 LEU 149 0.0002

LEU 149 ALA 150 0.0000

ALA 150 TYR 151 -0.0073

TYR 151 GLU 152 0.0001

GLU 152 LEU 153 -0.0003

LEU 153 ASP 154 -0.0001

ASP 154 ALA 155 -0.0002

ALA 155 THR 156 0.0001

THR 156 LEU 157 0.0003

LEU 157 VAL 158 -0.0001

VAL 158 SER 159 0.0000

SER 159 ALA 160 -0.0004

ALA 160 ASP 161 -0.0277

ASP 161 GLU 162 0.0003

GLU 162 GLY 163 0.0001

GLY 163 MET 164 0.0001

MET 164 ARG 165 -0.0002

ARG 165 LYS 166 -0.0000

LYS 166 PHE 167 -0.0002

PHE 167 ALA 168 -0.0002

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 -0.0002

ARG 170 ILE 171 0.0184

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0001

ILE 173 LYS 174 0.0004

LYS 174 LEU 175 0.0003

LEU 175 VAL 176 -0.0003

VAL 176 ASN 177 0.0002

ASN 177 PRO 178 -0.0002

PRO 178 ARG 179 0.0001

ARG 179 TYR 180 -0.0003

TYR 180 LEU 181 -0.0004

LEU 181 ARG 182 0.0002

ARG 182 GLY 183 -0.0001

GLY 183 VAL 184 0.0001

VAL 184 MET 185 0.0001

MET 185 GLN 186 0.0001

GLN 186 ASN 187 0.0003

ASN 187 LEU 188 -0.0003

LEU 188 ALA 189 0.0000

ALA 189 SER 1 0.0244

SER 1 ARG 2 0.0002

ARG 2 ARG 3 0.0002

ARG 3 PHE 4 -0.0000

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 0.0002

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0004

THR 8 SER 9 0.0000

SER 9 VAL 10 -0.0003

VAL 10 PHE 11 0.0013

PHE 11 THR 12 0.0004

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 0.0003

ASP 15 VAL 16 -0.0002

VAL 16 TYR 17 -0.0002

TYR 17 LEU 18 0.0003

LEU 18 ARG 19 -0.0000

ARG 19 PHE 20 -0.0000

PHE 20 ASP 21 0.0099

ASP 21 GLU 22 0.0004

GLU 22 GLU 23 -0.0004

GLU 23 PRO 24 -0.0001

PRO 24 MET 25 -0.0003

MET 25 GLN 26 0.0000

GLN 26 ALA 27 0.0003

ALA 27 ILE 28 0.0000

ILE 28 SER 29 0.0000

SER 29 VAL 30 0.0001

VAL 30 PHE 31 0.0060

PHE 31 LEU 32 0.0002

LEU 32 GLY 33 -0.0000

GLY 33 LEU 34 0.0002

LEU 34 ALA 35 0.0001

ALA 35 ARG 36 -0.0001

ARG 36 ARG 37 0.0000

ARG 37 ALA 38 -0.0003

ALA 38 ASP 39 -0.0004

ASP 39 ALA 40 -0.0003

ALA 40 GLU 41 -0.0430

GLU 41 PHE 42 -0.0000

PHE 42 TYR 43 -0.0002

TYR 43 MET 44 0.0001

MET 44 PRO 45 0.0000

PRO 45 GLY 46 0.0001

GLY 46 PRO 47 0.0003

PRO 47 VAL 48 0.0001

VAL 48 TYR 49 -0.0000

TYR 49 GLN 50 -0.0000

GLN 50 GLU 51 0.0283

GLU 51 LEU 52 -0.0001

LEU 52 CYS 53 0.0000

CYS 53 ASN 54 -0.0002

ASN 54 LEU 55 -0.0002

LEU 55 ARG 56 0.0001

ARG 56 SER 57 0.0000

SER 57 MET 58 -0.0002

MET 58 ASP 59 0.0001

ASP 59 LEU 60 -0.0002

LEU 60 ILE 61 0.0116

ILE 61 GLY 62 0.0003

GLY 62 ALA 63 -0.0002

ALA 63 GLU 64 0.0002

GLU 64 PHE 65 0.0001

PHE 65 GLU 66 0.0000

GLU 66 THR 67 -0.0002

THR 67 GLU 68 -0.0002

GLU 68 VAL 69 0.0000

VAL 69 TYR 70 -0.0002

TYR 70 ILE 71 -0.0167

ILE 71 ARG 72 0.0003

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 0.0001

ARG 75 ARG 76 0.0004

ARG 76 PHE 77 0.0002

PHE 77 SER 78 -0.0000

SER 78 MET 79 -0.0002

MET 79 THR 80 0.0002

THR 80 ILE 81 -0.0017

ILE 81 PRO 82 0.0000

PRO 82 SER 83 -0.0002

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 -0.0002

VAL 85 LEU 86 -0.0000

LEU 86 TYR 87 -0.0000

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 -0.0000

PHE 89 ILE 90 0.0000

ILE 90 GLU 91 0.0016

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 -0.0003

ARG 94 THR 95 0.0001

THR 95 ARG 96 -0.0003

ARG 96 ILE 97 -0.0001

ILE 97 GLN 98 -0.0005

GLN 98 GLU 131 -0.0027

GLU 131 ALA 132 -0.0002

ALA 132 MET 133 0.0001

MET 133 ARG 134 -0.0002

ARG 134 ARG 135 0.0003

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 -0.0003

ILE 137 LEU 138 -0.0000

LEU 138 ASP 139 0.0002

ASP 139 SER 140 0.0003

SER 140 ARG 141 -0.0046

ARG 141 GLU 142 0.0003

GLU 142 ASP 143 0.0004

ASP 143 ILE 144 -0.0002

ILE 144 ASP 145 0.0006

ASP 145 VAL 146 0.0003

VAL 146 VAL 147 -0.0001

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 -0.0001

LEU 149 ALA 150 -0.0003

ALA 150 TYR 151 0.0072

TYR 151 GLU 152 0.0001

GLU 152 LEU 153 -0.0003

LEU 153 ASP 154 0.0000

ASP 154 ALA 155 -0.0001

ALA 155 THR 156 0.0004

THR 156 LEU 157 -0.0000

LEU 157 VAL 158 0.0002

VAL 158 SER 159 0.0002

SER 159 ALA 160 -0.0003

ALA 160 ASP 161 -0.0078

ASP 161 GLU 162 -0.0000

GLU 162 GLY 163 -0.0002

GLY 163 MET 164 -0.0001

MET 164 ARG 165 0.0003

ARG 165 LYS 166 -0.0004

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 -0.0001

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 0.0002

ARG 170 ILE 171 -0.0080

ILE 171 GLY 172 -0.0001

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 -0.0000

LYS 174 LEU 175 0.0004

LEU 175 VAL 176 -0.0003

VAL 176 ASN 177 -0.0002

ASN 177 PRO 178 -0.0002

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 -0.0000

TYR 180 LEU 181 -0.0163

LEU 181 ARG 182 -0.0004

ARG 182 GLY 183 0.0003

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 0.0000

MET 185 GLN 186 0.0000

GLN 186 ASN 187 -0.0001

ASN 187 LEU 188 -0.0001

LEU 188 ALA 189 -0.0000

ALA 189 ARG 2 -0.0178

ARG 2 ARG 3 0.0003

ARG 3 PHE 4 -0.0000

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0002

SER 9 VAL 10 0.0001

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 -0.0121

THR 12 ASN 13 -0.0000

ASN 13 PRO 14 0.0003

PRO 14 ASP 15 -0.0003

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0001

TYR 17 LEU 18 0.0001

LEU 18 ARG 19 0.0003

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 -0.0002

ASP 21 GLU 22 0.0058

GLU 22 GLU 23 0.0004

GLU 23 PRO 24 -0.0003

PRO 24 MET 25 -0.0001

MET 25 GLN 26 0.0001

GLN 26 ALA 27 -0.0001

ALA 27 ILE 28 0.0001

ILE 28 SER 29 -0.0001

SER 29 VAL 30 -0.0002

VAL 30 PHE 31 0.0001

PHE 31 LEU 32 -0.0012

LEU 32 GLY 33 0.0000

GLY 33 LEU 34 0.0004

LEU 34 ALA 35 -0.0001

ALA 35 ARG 36 -0.0000

ARG 36 ARG 37 0.0002

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 -0.0004

ALA 40 GLU 41 0.0001

GLU 41 PHE 42 0.0435

PHE 42 TYR 43 -0.0001

TYR 43 MET 44 0.0002

MET 44 PRO 45 0.0001

PRO 45 GLY 46 0.0004

GLY 46 PRO 47 -0.0003

PRO 47 VAL 48 -0.0002

VAL 48 TYR 49 -0.0004

TYR 49 GLN 50 -0.0001

GLN 50 GLU 51 0.0003

GLU 51 LEU 52 0.0033

LEU 52 CYS 53 -0.0002

CYS 53 ASN 54 0.0003

ASN 54 LEU 55 0.0003

LEU 55 ARG 56 -0.0005

ARG 56 SER 57 0.0004

SER 57 MET 58 -0.0001

MET 58 ASP 59 0.0002

ASP 59 LEU 60 0.0001

LEU 60 ILE 61 0.0002

ILE 61 GLY 62 -0.0075

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 0.0001

GLU 64 PHE 65 -0.0000

PHE 65 GLU 66 -0.0002

GLU 66 THR 67 0.0002

THR 67 GLU 68 -0.0003

GLU 68 VAL 69 -0.0001

VAL 69 TYR 70 -0.0004

TYR 70 ILE 71 0.0001

ILE 71 ARG 72 0.0068

ARG 72 SER 73 0.0003

SER 73 PRO 74 -0.0000

PRO 74 ARG 75 -0.0003

ARG 75 ARG 76 0.0000

ARG 76 PHE 77 -0.0001

PHE 77 SER 78 0.0001

SER 78 MET 79 -0.0000

MET 79 THR 80 0.0001

THR 80 ILE 81 -0.0002

ILE 81 PRO 82 -0.0427

PRO 82 SER 83 0.0004

SER 83 GLU 84 0.0001

GLU 84 VAL 85 0.0001

VAL 85 LEU 86 -0.0004

LEU 86 TYR 87 -0.0000

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 -0.0002

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 0.0003

GLU 91 GLU 92 0.0077

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 0.0003

ARG 94 THR 95 0.0001

THR 95 ARG 96 -0.0004

ARG 96 ILE 97 -0.0004

ILE 97 GLN 98 -0.0000

GLN 98 GLU 131 0.0008

GLU 131 ALA 132 -0.0002

ALA 132 MET 133 0.0001

MET 133 ARG 134 -0.0003

ARG 134 ARG 135 0.0001

ARG 135 GLY 136 -0.0001

GLY 136 ILE 137 0.0001

ILE 137 LEU 138 -0.0001

LEU 138 ASP 139 -0.0001

ASP 139 SER 140 -0.0004

SER 140 ARG 141 -0.0096

ARG 141 GLU 142 -0.0002

GLU 142 ASP 143 0.0002

ASP 143 ILE 144 -0.0000

ILE 144 ASP 145 0.0005

ASP 145 VAL 146 -0.0001

VAL 146 VAL 147 -0.0001

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0002

ALA 150 TYR 151 -0.0044

TYR 151 GLU 152 -0.0003

GLU 152 LEU 153 -0.0004

LEU 153 ASP 154 0.0002

ASP 154 ALA 155 0.0002

ALA 155 THR 156 0.0000

THR 156 LEU 157 -0.0004

LEU 157 VAL 158 -0.0003

VAL 158 SER 159 0.0001

SER 159 ALA 160 -0.0001

ALA 160 ASP 161 0.0313

ASP 161 GLU 162 0.0003

GLU 162 GLY 163 -0.0001

GLY 163 MET 164 0.0004

MET 164 ARG 165 0.0001

ARG 165 LYS 166 -0.0003

LYS 166 PHE 167 0.0003

PHE 167 ALA 168 -0.0002

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 0.0002

ARG 170 ILE 171 0.0137

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0001

ILE 173 LYS 174 -0.0001

LYS 174 LEU 175 -0.0000

LEU 175 VAL 176 0.0004

VAL 176 ASN 177 -0.0003

ASN 177 PRO 178 -0.0001

PRO 178 ARG 179 0.0002

ARG 179 TYR 180 -0.0001

TYR 180 LEU 181 -0.0197

LEU 181 ARG 182 0.0002

ARG 182 GLY 183 0.0002

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 -0.0000

MET 185 GLN 186 0.0000

GLN 186 ASN 187 -0.0001

ASN 187 LEU 188 0.0001

LEU 188 ALA 189 0.0002

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** HYDROLASE 06-MAY-21 7OG5 ***

CA strain for 22121317415457420

--- normal mode 8 ---

Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE 06-MAY-21 7OG5 *