Should you encounter any unexpected behaviour,
please let us know.

* *

CA strain for 22121317404857062

--- normal mode 8 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 ASP 2 0.0004

ASP 2 THR 3 0.0000

THR 3 PHE 4 0.0000

PHE 4 VAL 5 -0.0000

VAL 5 LEU 6 0.0003

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0003

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0000

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 -0.0022

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0002

TYR 17 HIS 18 -0.0000

HIS 18 GLN 19 -0.0000

GLN 19 PHE 20 0.0000

PHE 20 GLU 21 -0.0004

GLU 21 GLU 22 0.0004

GLU 22 ASP 23 0.0088

ASP 23 GLN 24 0.0001

GLN 24 LEU 25 -0.0001

LEU 25 GLY 26 0.0001

GLY 26 ALA 27 0.0003

ALA 27 ILE 28 0.0000

ILE 28 GLU 29 0.0003

GLU 29 ASN 30 0.0004

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 -0.0002

ILE 32 SER 33 -0.0001

SER 33 LEU 34 -0.0116

LEU 34 ALA 35 0.0003

ALA 35 SER 36 -0.0003

SER 36 HIS 37 -0.0001

HIS 37 THR 38 -0.0004

THR 38 ASN 39 0.0002

ASN 39 ALA 40 0.0004

ALA 40 ASN 41 0.0001

ASN 41 PHE 42 -0.0002

PHE 42 PHE 43 0.0003

PHE 43 MET 44 -0.0001

MET 44 PRO 45 0.0010

PRO 45 THR 46 -0.0001

THR 46 SER 47 0.0001

SER 47 VAL 48 0.0004

VAL 48 TYR 49 0.0000

TYR 49 TYR 50 -0.0000

TYR 50 GLU 51 0.0001

GLU 51 PHE 52 0.0000

PHE 52 THR 53 0.0001

THR 53 LYS 54 0.0002

LYS 54 MET 55 -0.0000

MET 55 VAL 56 -0.0011

VAL 56 SER 57 -0.0001

SER 57 LEU 58 -0.0001

LEU 58 GLY 59 0.0002

GLY 59 ASP 60 -0.0003

ASP 60 LEU 61 0.0002

LEU 61 ALA 62 -0.0001

ALA 62 PRO 63 0.0003

PRO 63 LYS 64 -0.0000

LYS 64 PHE 65 0.0002

PHE 65 GLU 66 -0.0003

GLU 66 LEU 67 -0.0105

LEU 67 VAL 68 0.0002

VAL 68 VAL 69 0.0003

VAL 69 ARG 70 -0.0003

ARG 70 ILE 71 -0.0000

ILE 71 ARG 72 -0.0002

ARG 72 SER 73 -0.0002

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 0.0001

ARG 75 LYS 76 -0.0000

LYS 76 TRP 77 -0.0001

TRP 77 GLY 78 0.0098

GLY 78 LEU 79 0.0002

LEU 79 MET 80 0.0000

MET 80 VAL 81 0.0004

VAL 81 PRO 82 -0.0000

PRO 82 ALA 83 -0.0002

ALA 83 GLU 84 0.0003

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 -0.0002

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 -0.0000

GLU 88 PHE 89 0.0019

PHE 89 ILE 90 -0.0003

ILE 90 GLU 91 0.0000

GLU 91 GLU 92 -0.0002

GLU 92 VAL 93 0.0002

VAL 93 ARG 94 0.0001

ARG 94 TYR 95 -0.0002

TYR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0001

ILE 97 ASN 98 0.0001

ASN 98 LYS 99 -0.0001

LYS 99 GLY 100 -0.0022

GLY 100 LEU 101 -0.0000

LEU 101 ARG 102 -0.0001

ARG 102 ILE 103 0.0001

ILE 103 ALA 104 0.0005

ALA 104 GLU 105 0.0001

GLU 105 GLU 106 -0.0001

GLU 106 HIS 107 -0.0000

HIS 107 ARG 125 -0.0006

ARG 125 LEU 126 -0.0003

LEU 126 ARG 127 -0.0005

ARG 127 GLU 128 0.0000

GLU 128 LYS 129 -0.0005

LYS 129 TYR 130 -0.0002

TYR 130 ARG 131 -0.0001

ARG 131 GLU 132 -0.0003

GLU 132 ALA 133 -0.0003

ALA 133 LEU 134 0.0003

LEU 134 ARG 135 0.0001

ARG 135 ALA 136 0.0028

ALA 136 GLY 137 -0.0003

GLY 137 ILE 138 -0.0002

ILE 138 ILE 139 -0.0004

ILE 139 ASP 140 0.0000

ASP 140 SER 141 0.0002

SER 141 LYS 142 0.0000

LYS 142 GLU 143 -0.0003

GLU 143 ASP 144 0.0001

ASP 144 VAL 145 0.0001

VAL 145 ASP 146 -0.0003

ASP 146 VAL 147 -0.0027

VAL 147 LEU 148 0.0000

LEU 148 LEU 149 -0.0001

LEU 149 LEU 150 0.0003

LEU 150 SER 151 -0.0002

SER 151 TYR 152 0.0002

TYR 152 GLU 153 0.0003

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 0.0000

ASP 155 ALA 156 -0.0001

ALA 156 ILE 157 0.0002

ILE 157 LEU 158 0.0020

LEU 158 VAL 159 -0.0000

VAL 159 SER 160 -0.0000

SER 160 GLY 161 0.0002

GLY 161 ASP 162 -0.0000

ASP 162 GLU 163 0.0005

GLU 163 GLY 164 -0.0000

GLY 164 LEU 165 -0.0002

LEU 165 ARG 166 0.0003

ARG 166 LYS 167 0.0001

LYS 167 TRP 168 0.0004

TRP 168 ALA 169 0.0032

ALA 169 ASP 170 -0.0001

ASP 170 ARG 171 0.0002

ARG 171 VAL 172 0.0001

VAL 172 GLY 173 0.0001

GLY 173 ILE 174 -0.0002

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 0.0002

LEU 176 ILE 177 0.0002

ILE 177 ASP 178 -0.0001

ASP 178 PRO 179 0.0001

PRO 179 LYS 180 0.0021

LYS 180 ASN 181 0.0004

ASN 181 LEU 182 0.0001

LEU 182 ARG 183 0.0002

ARG 183 TYR 184 -0.0004

TYR 184 ILE 185 -0.0002

ILE 185 MET 186 -0.0001

MET 186 GLU 187 -0.0002

GLU 187 ASN 188 -0.0001

ASN 188 LEU 189 -0.0002

LEU 189 THR 190 -0.0004

THR 190 MET 1 -0.0007

MET 1 ASP 2 -0.0000

ASP 2 THR 3 0.0002

THR 3 PHE 4 -0.0003

PHE 4 VAL 5 -0.0000

VAL 5 LEU 6 -0.0003

LEU 6 ASP 7 0.0002

ASP 7 THR 8 -0.0002

THR 8 SER 9 -0.0005

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0002

PHE 11 THR 12 -0.0027

THR 12 ASN 13 0.0000

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 -0.0003

ASP 15 VAL 16 -0.0001

VAL 16 TYR 17 -0.0000

TYR 17 HIS 18 -0.0001

HIS 18 GLN 19 0.0003

GLN 19 PHE 20 0.0000

PHE 20 GLU 21 0.0000

GLU 21 GLU 22 0.0001

GLU 22 ASP 23 -0.0022

ASP 23 GLN 24 0.0004

GLN 24 LEU 25 -0.0001

LEU 25 GLY 26 -0.0001

GLY 26 ALA 27 0.0001

ALA 27 ILE 28 -0.0003

ILE 28 GLU 29 -0.0002

GLU 29 ASN 30 -0.0001

ASN 30 PHE 31 -0.0003

PHE 31 ILE 32 0.0000

ILE 32 SER 33 -0.0002

SER 33 LEU 34 0.0024

LEU 34 ALA 35 -0.0002

ALA 35 SER 36 -0.0004

SER 36 HIS 37 -0.0002

HIS 37 THR 38 -0.0005

THR 38 ASN 39 0.0001

ASN 39 ALA 40 0.0004

ALA 40 ASN 41 -0.0000

ASN 41 PHE 42 -0.0002

PHE 42 PHE 43 -0.0001

PHE 43 MET 44 -0.0000

MET 44 PRO 45 -0.0019

PRO 45 THR 46 0.0004

THR 46 SER 47 0.0001

SER 47 VAL 48 0.0002

VAL 48 TYR 49 0.0001

TYR 49 TYR 50 -0.0002

TYR 50 GLU 51 -0.0002

GLU 51 PHE 52 0.0002

PHE 52 THR 53 0.0001

THR 53 LYS 54 -0.0001

LYS 54 MET 55 -0.0005

MET 55 VAL 56 -0.0015

VAL 56 SER 57 -0.0001

SER 57 LEU 58 -0.0004

LEU 58 GLY 59 -0.0001

GLY 59 ASP 60 0.0000

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 0.0001

ALA 62 PRO 63 0.0005

PRO 63 LYS 64 0.0002

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 0.0000

GLU 66 LEU 67 -0.0012

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 0.0001

VAL 69 ARG 70 0.0001

ARG 70 ILE 71 -0.0004

ILE 71 ARG 72 -0.0002

ARG 72 SER 73 0.0003

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 0.0002

ARG 75 LYS 76 0.0003

LYS 76 TRP 77 -0.0001

TRP 77 GLY 78 0.0009

GLY 78 LEU 79 -0.0003

LEU 79 MET 80 -0.0001

MET 80 VAL 81 -0.0002

VAL 81 PRO 82 -0.0001

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 0.0002

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 0.0002

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 0.0002

GLU 88 PHE 89 0.0009

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 -0.0002

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 0.0003

ARG 94 TYR 95 0.0003

TYR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0003

ILE 97 ASN 98 -0.0001

ASN 98 LYS 99 0.0003

LYS 99 GLY 100 0.0054

GLY 100 LEU 101 -0.0001

LEU 101 ARG 102 0.0000

ARG 102 ILE 103 0.0002

ILE 103 ALA 104 -0.0000

ALA 104 GLU 105 -0.0000

GLU 105 GLU 106 -0.0002

GLU 106 HIS 107 -0.0000

HIS 107 THR 108 -0.0003

THR 108 LEU 126 -0.0007

LEU 126 ARG 127 -0.0001

ARG 127 GLU 128 0.0002

GLU 128 LYS 129 0.0001

LYS 129 TYR 130 0.0001

TYR 130 ARG 131 0.0001

ARG 131 GLU 132 0.0003

GLU 132 ALA 133 -0.0003

ALA 133 LEU 134 0.0001

LEU 134 ARG 135 -0.0000

ARG 135 ALA 136 -0.0002

ALA 136 GLY 137 0.0084

GLY 137 ILE 138 0.0003

ILE 138 ILE 139 -0.0000

ILE 139 ASP 140 0.0002

ASP 140 SER 141 -0.0003

SER 141 LYS 142 -0.0001

LYS 142 GLU 143 -0.0003

GLU 143 ASP 144 -0.0002

ASP 144 VAL 145 0.0001

VAL 145 ASP 146 -0.0005

ASP 146 VAL 147 -0.0001

VAL 147 LEU 148 -0.0019

LEU 148 LEU 149 0.0000

LEU 149 LEU 150 -0.0001

LEU 150 SER 151 0.0001

SER 151 TYR 152 0.0003

TYR 152 GLU 153 0.0002

GLU 153 LEU 154 0.0001

LEU 154 ASP 155 -0.0002

ASP 155 ALA 156 -0.0002

ALA 156 ILE 157 -0.0002

ILE 157 LEU 158 -0.0004

LEU 158 VAL 159 -0.0042

VAL 159 SER 160 -0.0002

SER 160 GLY 161 0.0002

GLY 161 ASP 162 0.0003

ASP 162 GLU 163 0.0003

GLU 163 GLY 164 -0.0000

GLY 164 LEU 165 -0.0001

LEU 165 ARG 166 0.0001

ARG 166 LYS 167 0.0002

LYS 167 TRP 168 0.0002

TRP 168 ALA 169 0.0005

ALA 169 ASP 170 0.0097

ASP 170 ARG 171 0.0000

ARG 171 VAL 172 0.0003

VAL 172 GLY 173 -0.0001

GLY 173 ILE 174 0.0001

ILE 174 LYS 175 -0.0001

LYS 175 LEU 176 -0.0003

LEU 176 ILE 177 -0.0001

ILE 177 ASP 178 -0.0003

ASP 178 PRO 179 -0.0001

PRO 179 LYS 180 0.0003

LYS 180 ASN 181 0.0050

ASN 181 LEU 182 -0.0001

LEU 182 ARG 183 -0.0001

ARG 183 TYR 184 0.0003

TYR 184 ILE 185 -0.0002

ILE 185 MET 186 0.0001

MET 186 GLU 187 0.0000

GLU 187 ASN 188 0.0003

ASN 188 LEU 189 -0.0001

LEU 189 THR 190 -0.0001

THR 190 LYS 191 0.0003

LYS 191 VAL 192 0.0071

VAL 192 GLY 193 0.0002

GLY 193 ARG 194 0.0000

ARG 194 MET 1 -0.0088

MET 1 ASP 2 0.0001

ASP 2 THR 3 -0.0002

THR 3 PHE 4 0.0002

PHE 4 VAL 5 -0.0003

VAL 5 LEU 6 0.0003

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 -0.0000

THR 8 SER 9 0.0001

SER 9 VAL 10 0.0004

VAL 10 PHE 11 0.0002

PHE 11 THR 12 0.0075

THR 12 ASN 13 -0.0003

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 0.0004

VAL 16 TYR 17 0.0001

TYR 17 HIS 18 -0.0001

HIS 18 GLN 19 -0.0001

GLN 19 PHE 20 -0.0002

PHE 20 GLU 21 0.0003

GLU 21 GLU 22 -0.0003

GLU 22 ASP 23 -0.0033

ASP 23 GLN 24 0.0001

GLN 24 LEU 25 0.0000

LEU 25 GLY 26 0.0000

GLY 26 ALA 27 -0.0002

ALA 27 ILE 28 -0.0001

ILE 28 GLU 29 0.0001

GLU 29 ASN 30 0.0001

ASN 30 PHE 31 -0.0001

PHE 31 ILE 32 0.0001

ILE 32 SER 33 0.0004

SER 33 LEU 34 -0.0064

LEU 34 ALA 35 -0.0003

ALA 35 SER 36 -0.0001

SER 36 HIS 37 0.0002

HIS 37 THR 38 -0.0002

THR 38 ASN 39 0.0004

ASN 39 ALA 40 -0.0001

ALA 40 ASN 41 0.0000

ASN 41 PHE 42 -0.0003

PHE 42 PHE 43 0.0001

PHE 43 MET 44 0.0002

MET 44 PRO 45 -0.0063

PRO 45 THR 46 0.0003

THR 46 SER 47 -0.0002

SER 47 VAL 48 -0.0000

VAL 48 TYR 49 -0.0000

TYR 49 TYR 50 -0.0002

TYR 50 GLU 51 0.0003

GLU 51 PHE 52 -0.0002

PHE 52 THR 53 -0.0000

THR 53 LYS 54 -0.0001

LYS 54 MET 55 0.0000

MET 55 VAL 56 0.0020

VAL 56 SER 57 -0.0001

SER 57 LEU 58 -0.0002

LEU 58 GLY 59 0.0002

GLY 59 ASP 60 -0.0000

ASP 60 LEU 61 0.0000

LEU 61 ALA 62 0.0001

ALA 62 PRO 63 -0.0002

PRO 63 LYS 64 0.0000

LYS 64 PHE 65 0.0003

PHE 65 GLU 66 -0.0001

GLU 66 LEU 67 -0.0003

LEU 67 VAL 68 0.0002

VAL 68 VAL 69 -0.0001

VAL 69 ARG 70 0.0004

ARG 70 ILE 71 0.0002

ILE 71 ARG 72 -0.0002

ARG 72 SER 73 0.0003

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 0.0002

ARG 75 LYS 76 0.0003

LYS 76 TRP 77 -0.0000

TRP 77 GLY 78 -0.0019

GLY 78 LEU 79 0.0002

LEU 79 MET 80 0.0001

MET 80 VAL 81 -0.0000

VAL 81 PRO 82 0.0002

PRO 82 ALA 83 0.0000

ALA 83 GLU 84 0.0002

GLU 84 PHE 85 -0.0001

PHE 85 LEU 86 0.0004

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 -0.0002

GLU 88 PHE 89 0.0052

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 -0.0000

GLU 91 GLU 92 0.0002

GLU 92 VAL 93 -0.0003

VAL 93 ARG 94 -0.0003

ARG 94 TYR 95 0.0000

TYR 95 ARG 96 -0.0004

ARG 96 ILE 97 -0.0000

ILE 97 ASN 98 0.0001

ASN 98 LYS 99 0.0003

LYS 99 GLY 100 0.0006

GLY 100 LEU 101 0.0000

LEU 101 ARG 102 0.0001

ARG 102 ILE 103 0.0002

ILE 103 ALA 104 -0.0000

ALA 104 GLU 105 0.0003

GLU 105 GLU 106 0.0001

GLU 106 HIS 107 -0.0001

HIS 107 THR 108 -0.0003

THR 108 LEU 126 -0.0000

LEU 126 ARG 127 -0.0000

ARG 127 GLU 128 -0.0002

GLU 128 LYS 129 0.0001

LYS 129 TYR 130 0.0001

TYR 130 ARG 131 -0.0001

ARG 131 GLU 132 -0.0000

GLU 132 ALA 133 -0.0001

ALA 133 LEU 134 0.0001

LEU 134 ARG 135 0.0001

ARG 135 ALA 136 0.0002

ALA 136 GLY 137 -0.0047

GLY 137 ILE 138 -0.0001

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0000

ASP 140 SER 141 0.0002

SER 141 LYS 142 0.0003

LYS 142 GLU 143 0.0001

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 -0.0002

VAL 145 ASP 146 -0.0003

ASP 146 VAL 147 -0.0000

VAL 147 LEU 148 0.0010

LEU 148 LEU 149 -0.0000

LEU 149 LEU 150 0.0002

LEU 150 SER 151 0.0002

SER 151 TYR 152 -0.0000

TYR 152 GLU 153 -0.0003

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 -0.0001

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 -0.0001

ILE 157 LEU 158 -0.0001

LEU 158 VAL 159 0.0084

VAL 159 SER 160 -0.0005

SER 160 GLY 161 0.0001

GLY 161 ASP 162 0.0000

ASP 162 GLU 163 0.0003

GLU 163 GLY 164 -0.0001

GLY 164 LEU 165 -0.0001

LEU 165 ARG 166 0.0001

ARG 166 LYS 167 0.0000

LYS 167 TRP 168 0.0000

TRP 168 ALA 169 -0.0000

ALA 169 ASP 170 -0.0045

ASP 170 ARG 171 -0.0001

ARG 171 VAL 172 0.0002

VAL 172 GLY 173 0.0001

GLY 173 ILE 174 -0.0000

ILE 174 LYS 175 -0.0003

LYS 175 LEU 176 -0.0001

LEU 176 ILE 177 0.0003

ILE 177 ASP 178 0.0002

ASP 178 PRO 179 -0.0001

PRO 179 LYS 180 -0.0002

LYS 180 ASN 181 -0.0179

ASN 181 LEU 182 -0.0001

LEU 182 ARG 183 -0.0003

ARG 183 TYR 184 -0.0000

TYR 184 ILE 185 0.0001

ILE 185 MET 186 -0.0001

MET 186 GLU 187 -0.0002

GLU 187 ASN 188 0.0001

ASN 188 LEU 189 -0.0004

LEU 189 THR 190 -0.0001

THR 190 LYS 191 -0.0000

LYS 191 VAL 192 -0.0007

VAL 192 GLY 193 0.0001

GLY 193 ARG 194 0.0000

ARG 194 MET 1 0.0014

MET 1 ASP 2 0.0001

ASP 2 THR 3 0.0000

THR 3 PHE 4 -0.0003

PHE 4 VAL 5 0.0000

VAL 5 LEU 6 -0.0003

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 0.0004

THR 8 SER 9 0.0001

SER 9 VAL 10 -0.0004

VAL 10 PHE 11 0.0000

PHE 11 THR 12 0.0014

THR 12 ASN 13 0.0004

ASN 13 PRO 14 0.0004

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 0.0007

TYR 17 HIS 18 -0.0001

HIS 18 GLN 19 0.0001

GLN 19 PHE 20 0.0001

PHE 20 GLU 21 -0.0003

GLU 21 GLU 22 0.0003

GLU 22 ASP 23 0.0012

ASP 23 GLN 24 -0.0002

GLN 24 LEU 25 0.0002

LEU 25 GLY 26 -0.0002

GLY 26 ALA 27 -0.0003

ALA 27 ILE 28 0.0002

ILE 28 GLU 29 0.0001

GLU 29 ASN 30 -0.0000

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 0.0002

ILE 32 SER 33 -0.0001

SER 33 LEU 34 0.0022

LEU 34 ALA 35 -0.0002

ALA 35 SER 36 -0.0002

SER 36 HIS 37 0.0003

HIS 37 THR 38 -0.0000

THR 38 ASN 39 0.0004

ASN 39 ALA 40 0.0002

ALA 40 ASN 41 0.0000

ASN 41 PHE 42 -0.0002

PHE 42 PHE 43 0.0001

PHE 43 MET 44 -0.0002

MET 44 PRO 45 0.0057

PRO 45 THR 46 -0.0003

THR 46 SER 47 0.0003

SER 47 VAL 48 -0.0002

VAL 48 TYR 49 0.0001

TYR 49 TYR 50 -0.0000

TYR 50 GLU 51 -0.0003

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 0.0003

THR 53 LYS 54 0.0001

LYS 54 MET 55 0.0001

MET 55 VAL 56 0.0007

VAL 56 SER 57 0.0003

SER 57 LEU 58 -0.0002

LEU 58 GLY 59 0.0001

GLY 59 ASP 60 -0.0004

ASP 60 LEU 61 0.0002

LEU 61 ALA 62 0.0004

ALA 62 PRO 63 -0.0001

PRO 63 LYS 64 -0.0002

LYS 64 PHE 65 0.0005

PHE 65 GLU 66 -0.0000

GLU 66 LEU 67 -0.0021

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 -0.0003

VAL 69 ARG 70 0.0001

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 0.0004

ARG 72 SER 73 -0.0004

SER 73 PRO 74 -0.0001

PRO 74 ARG 75 0.0001

ARG 75 LYS 76 -0.0001

LYS 76 TRP 77 0.0002

TRP 77 GLY 78 -0.0223

GLY 78 LEU 79 0.0001

LEU 79 MET 80 0.0001

MET 80 VAL 81 0.0000

VAL 81 PRO 82 0.0004

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 0.0002

GLU 84 PHE 85 -0.0001

PHE 85 LEU 86 -0.0001

LEU 86 TYR 87 -0.0001

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 0.0025

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 0.0004

GLU 91 GLU 92 0.0004

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 0.0000

ARG 94 TYR 95 0.0001

TYR 95 ARG 96 0.0002

ARG 96 ILE 97 -0.0002

ILE 97 ASN 98 0.0003

ASN 98 LYS 99 -0.0002

LYS 99 GLY 100 -0.0041

GLY 100 LEU 101 -0.0003

LEU 101 ARG 102 0.0000

ARG 102 ILE 103 -0.0001

ILE 103 ALA 104 -0.0003

ALA 104 GLU 105 0.0001

GLU 105 GLU 106 -0.0000

GLU 106 HIS 107 -0.0002

HIS 107 ARG 125 -0.0004

ARG 125 LEU 126 -0.0002

LEU 126 ARG 127 0.0000

ARG 127 GLU 128 -0.0001

GLU 128 LYS 129 -0.0004

LYS 129 TYR 130 -0.0004

TYR 130 ARG 131 0.0005

ARG 131 GLU 132 0.0001

GLU 132 ALA 133 -0.0001

ALA 133 LEU 134 -0.0005

LEU 134 ARG 135 0.0002

ARG 135 ALA 136 -0.0040

ALA 136 GLY 137 0.0002

GLY 137 ILE 138 0.0004

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 0.0002

ASP 140 SER 141 0.0001

SER 141 LYS 142 0.0002

LYS 142 GLU 143 -0.0004

GLU 143 ASP 144 0.0001

ASP 144 VAL 145 0.0001

VAL 145 ASP 146 -0.0003

ASP 146 VAL 147 0.0080

VAL 147 LEU 148 -0.0004

LEU 148 LEU 149 -0.0005

LEU 149 LEU 150 -0.0000

LEU 150 SER 151 -0.0002

SER 151 TYR 152 -0.0003

TYR 152 GLU 153 0.0003

GLU 153 LEU 154 -0.0004

LEU 154 ASP 155 -0.0000

ASP 155 ALA 156 0.0003

ALA 156 ILE 157 -0.0004

ILE 157 LEU 158 0.0001

LEU 158 VAL 159 0.0001

VAL 159 SER 160 -0.0003

SER 160 GLY 161 0.0004

GLY 161 ASP 162 0.0003

ASP 162 GLU 163 -0.0002

GLU 163 GLY 164 0.0003

GLY 164 LEU 165 -0.0002

LEU 165 ARG 166 -0.0000

ARG 166 LYS 167 -0.0003

LYS 167 TRP 168 -0.0001

TRP 168 ALA 169 -0.0046

ALA 169 ASP 170 0.0002

ASP 170 ARG 171 0.0004

ARG 171 VAL 172 -0.0001

VAL 172 GLY 173 -0.0002

GLY 173 ILE 174 -0.0002

ILE 174 LYS 175 -0.0003

LYS 175 LEU 176 0.0002

LEU 176 ILE 177 0.0001

ILE 177 ASP 178 0.0000

ASP 178 PRO 179 -0.0002

PRO 179 LYS 180 -0.0026

LYS 180 ASN 181 0.0000

ASN 181 LEU 182 0.0003

LEU 182 ARG 183 0.0003

ARG 183 TYR 184 0.0001

TYR 184 ILE 185 0.0001

ILE 185 MET 186 0.0001

MET 186 GLU 187 -0.0000

GLU 187 ASN 188 -0.0001

ASN 188 LEU 189 0.0001

LEU 189 THR 190 0.0002

THR 190 MET 1 -0.0025

MET 1 ASP 2 -0.0001

ASP 2 THR 3 0.0000

THR 3 PHE 4 0.0003

PHE 4 VAL 5 -0.0000

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0002

THR 8 SER 9 -0.0001

SER 9 VAL 10 0.0003

VAL 10 PHE 11 -0.0004

PHE 11 THR 12 0.0061

THR 12 ASN 13 0.0002

ASN 13 PRO 14 -0.0001

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0002

TYR 17 HIS 18 0.0000

HIS 18 GLN 19 0.0002

GLN 19 PHE 20 -0.0002

PHE 20 GLU 21 -0.0002

GLU 21 GLU 22 0.0002

GLU 22 ASP 23 -0.0088

ASP 23 GLN 24 0.0000

GLN 24 LEU 25 0.0002

LEU 25 GLY 26 0.0003

GLY 26 ALA 27 0.0002

ALA 27 ILE 28 -0.0001

ILE 28 GLU 29 -0.0001

GLU 29 ASN 30 -0.0001

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 0.0000

ILE 32 SER 33 -0.0002

SER 33 LEU 34 -0.0061

LEU 34 ALA 35 -0.0003

ALA 35 SER 36 0.0001

SER 36 HIS 37 -0.0003

HIS 37 THR 38 0.0001

THR 38 ASN 39 -0.0000

ASN 39 ALA 40 0.0001

ALA 40 ASN 41 0.0002

ASN 41 PHE 42 -0.0000

PHE 42 PHE 43 0.0002

PHE 43 MET 44 0.0001

MET 44 PRO 45 -0.0035

PRO 45 THR 46 0.0003

THR 46 SER 47 -0.0001

SER 47 VAL 48 -0.0000

VAL 48 TYR 49 0.0002

TYR 49 TYR 50 -0.0004

TYR 50 GLU 51 0.0000

GLU 51 PHE 52 0.0002

PHE 52 THR 53 0.0000

THR 53 LYS 54 -0.0003

LYS 54 MET 55 -0.0003

MET 55 VAL 56 0.0007

VAL 56 SER 57 -0.0002

SER 57 LEU 58 -0.0003

LEU 58 GLY 59 0.0000

GLY 59 ASP 60 0.0003

ASP 60 LEU 61 0.0002

LEU 61 ALA 62 0.0002

ALA 62 PRO 63 -0.0001

PRO 63 LYS 64 0.0001

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 -0.0002

GLU 66 LEU 67 -0.0017

LEU 67 VAL 68 -0.0004

VAL 68 VAL 69 0.0000

VAL 69 ARG 70 0.0005

ARG 70 ILE 71 -0.0001

ILE 71 ARG 72 0.0000

ARG 72 SER 73 0.0004

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 0.0003

ARG 75 LYS 76 -0.0002

LYS 76 TRP 77 0.0004

TRP 77 GLY 78 0.0043

GLY 78 LEU 79 -0.0001

LEU 79 MET 80 -0.0001

MET 80 VAL 81 0.0001

VAL 81 PRO 82 -0.0001

PRO 82 ALA 83 0.0002

ALA 83 GLU 84 0.0003

GLU 84 PHE 85 -0.0002

PHE 85 LEU 86 -0.0000

LEU 86 TYR 87 -0.0001

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 0.0034

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 -0.0000

GLU 91 GLU 92 -0.0003

GLU 92 VAL 93 0.0002

VAL 93 ARG 94 0.0000

ARG 94 TYR 95 -0.0000

TYR 95 ARG 96 -0.0003

ARG 96 ILE 97 -0.0003

ILE 97 ASN 98 0.0003

ASN 98 LYS 99 0.0003

LYS 99 GLY 100 0.0013

GLY 100 LEU 101 -0.0002

LEU 101 ARG 102 -0.0002

ARG 102 ILE 103 -0.0001

ILE 103 ALA 104 -0.0002

ALA 104 GLU 105 0.0002

GLU 105 GLU 106 0.0000

GLU 106 HIS 107 0.0001

HIS 107 THR 108 -0.0005

THR 108 LEU 126 0.0009

LEU 126 ARG 127 -0.0000

ARG 127 GLU 128 -0.0001

GLU 128 LYS 129 -0.0003

LYS 129 TYR 130 -0.0001

TYR 130 ARG 131 -0.0001

ARG 131 GLU 132 -0.0001

GLU 132 ALA 133 0.0002

ALA 133 LEU 134 0.0003

LEU 134 ARG 135 -0.0002

ARG 135 ALA 136 0.0001

ALA 136 GLY 137 -0.0009

GLY 137 ILE 138 0.0000

ILE 138 ILE 139 0.0000

ILE 139 ASP 140 -0.0001

ASP 140 SER 141 -0.0002

SER 141 LYS 142 -0.0000

LYS 142 GLU 143 0.0000

GLU 143 ASP 144 0.0001

ASP 144 VAL 145 0.0002

VAL 145 ASP 146 0.0000

ASP 146 VAL 147 -0.0003

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0000

LEU 149 LEU 150 0.0001

LEU 150 SER 151 -0.0001

SER 151 TYR 152 -0.0000

TYR 152 GLU 153 0.0002

GLU 153 LEU 154 0.0001

LEU 154 ASP 155 0.0005

ASP 155 ALA 156 0.0000

ALA 156 ILE 157 0.0003

ILE 157 LEU 158 -0.0002

LEU 158 VAL 159 0.0046

VAL 159 SER 160 0.0003

SER 160 GLY 161 -0.0001

GLY 161 ASP 162 -0.0002

ASP 162 GLU 163 -0.0000

GLU 163 GLY 164 0.0001

GLY 164 LEU 165 0.0003

LEU 165 ARG 166 -0.0000

ARG 166 LYS 167 -0.0002

LYS 167 TRP 168 0.0003

TRP 168 ALA 169 0.0001

ALA 169 ASP 170 -0.0087

ASP 170 ARG 171 -0.0003

ARG 171 VAL 172 -0.0001

VAL 172 GLY 173 0.0000

GLY 173 ILE 174 0.0002

ILE 174 LYS 175 0.0000

LYS 175 LEU 176 0.0003

LEU 176 ILE 177 -0.0002

ILE 177 ASP 178 -0.0003

ASP 178 PRO 179 0.0002

PRO 179 LYS 180 0.0001

LYS 180 ASN 181 -0.0049

ASN 181 LEU 182 -0.0003

LEU 182 ARG 183 -0.0001

ARG 183 TYR 184 0.0001

TYR 184 ILE 185 0.0002

ILE 185 MET 186 -0.0000

MET 186 GLU 187 -0.0001

GLU 187 ASN 188 -0.0002

ASN 188 LEU 189 -0.0004

LEU 189 THR 190 0.0000

THR 190 LYS 191 -0.0002

LYS 191 VAL 192 0.0123

VAL 192 GLY 193 0.0000

GLY 193 ARG 194 -0.0002

ARG 194 MET 1 -0.0018

MET 1 ASP 2 -0.0000

ASP 2 THR 3 -0.0002

THR 3 PHE 4 0.0003

PHE 4 VAL 5 -0.0005

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 0.0005

THR 8 SER 9 0.0002

SER 9 VAL 10 0.0001

VAL 10 PHE 11 -0.0003

PHE 11 THR 12 0.0017

THR 12 ASN 13 -0.0003

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 -0.0003

TYR 17 HIS 18 0.0002

HIS 18 GLN 19 -0.0002

GLN 19 PHE 20 -0.0002

PHE 20 GLU 21 0.0003

GLU 21 GLU 22 0.0001

GLU 22 ASP 23 -0.0023

ASP 23 GLN 24 -0.0001

GLN 24 LEU 25 -0.0000

LEU 25 GLY 26 -0.0001

GLY 26 ALA 27 0.0001

ALA 27 ILE 28 0.0001

ILE 28 GLU 29 -0.0003

GLU 29 ASN 30 0.0000

ASN 30 PHE 31 0.0001

PHE 31 ILE 32 0.0006

ILE 32 SER 33 0.0001

SER 33 LEU 34 -0.0014

LEU 34 ALA 35 0.0002

ALA 35 SER 36 0.0001

SER 36 HIS 37 0.0000

HIS 37 THR 38 0.0000

THR 38 ASN 39 -0.0004

ASN 39 ALA 40 0.0001

ALA 40 ASN 41 -0.0001

ASN 41 PHE 42 0.0002

PHE 42 PHE 43 0.0000

PHE 43 MET 44 0.0005

MET 44 PRO 45 -0.0009

PRO 45 THR 46 0.0004

THR 46 SER 47 0.0002

SER 47 VAL 48 0.0001

VAL 48 TYR 49 -0.0002

TYR 49 TYR 50 0.0003

TYR 50 GLU 51 0.0002

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 0.0000

THR 53 LYS 54 0.0002

LYS 54 MET 55 0.0004

MET 55 VAL 56 0.0038

VAL 56 SER 57 0.0000

SER 57 LEU 58 0.0002

LEU 58 GLY 59 -0.0004

GLY 59 ASP 60 0.0002

ASP 60 LEU 61 -0.0000

LEU 61 ALA 62 0.0002

ALA 62 PRO 63 -0.0001

PRO 63 LYS 64 0.0001

LYS 64 PHE 65 -0.0002

PHE 65 GLU 66 0.0000

GLU 66 LEU 67 -0.0041

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 0.0001

VAL 69 ARG 70 -0.0001

ARG 70 ILE 71 -0.0003

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 0.0003

ARG 75 LYS 76 -0.0003

LYS 76 TRP 77 0.0001

TRP 77 GLY 78 -0.0051

GLY 78 LEU 79 0.0003

LEU 79 MET 80 0.0002

MET 80 VAL 81 0.0001

VAL 81 PRO 82 0.0002

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 0.0002

GLU 84 PHE 85 -0.0002

PHE 85 LEU 86 0.0002

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 0.0002

GLU 88 PHE 89 0.0025

PHE 89 ILE 90 -0.0000

ILE 90 GLU 91 0.0002

GLU 91 GLU 92 -0.0003

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 0.0003

ARG 94 TYR 95 0.0001

TYR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0000

ILE 97 ASN 98 -0.0001

ASN 98 LYS 99 0.0004

LYS 99 GLY 100 -0.0029

GLY 100 LEU 101 0.0000

LEU 101 ARG 102 0.0002

ARG 102 ILE 103 -0.0002

ILE 103 ALA 104 -0.0003

ALA 104 GLU 105 -0.0002

GLU 105 GLU 106 -0.0002

GLU 106 HIS 107 0.0001

HIS 107 ARG 125 -0.0002

ARG 125 LEU 126 -0.0002

LEU 126 ARG 127 0.0002

ARG 127 GLU 128 0.0001

GLU 128 LYS 129 -0.0000

LYS 129 TYR 130 -0.0001

TYR 130 ARG 131 0.0001

ARG 131 GLU 132 -0.0003

GLU 132 ALA 133 0.0004

ALA 133 LEU 134 0.0002

LEU 134 ARG 135 0.0003

ARG 135 ALA 136 0.0040

ALA 136 GLY 137 0.0000

GLY 137 ILE 138 0.0002

ILE 138 ILE 139 0.0003

ILE 139 ASP 140 0.0003

ASP 140 SER 141 -0.0001

SER 141 LYS 142 0.0003

LYS 142 GLU 143 -0.0001

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 0.0000

VAL 145 ASP 146 -0.0000

ASP 146 VAL 147 0.0008

VAL 147 LEU 148 0.0003

LEU 148 LEU 149 0.0003

LEU 149 LEU 150 0.0001

LEU 150 SER 151 -0.0001

SER 151 TYR 152 0.0003

TYR 152 GLU 153 -0.0003

GLU 153 LEU 154 0.0001

LEU 154 ASP 155 -0.0000

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 -0.0001

ILE 157 LEU 158 0.0004

LEU 158 VAL 159 -0.0005

VAL 159 SER 160 0.0003

SER 160 GLY 161 0.0002

GLY 161 ASP 162 0.0003

ASP 162 GLU 163 -0.0001

GLU 163 GLY 164 -0.0002

GLY 164 LEU 165 -0.0004

LEU 165 ARG 166 -0.0003

ARG 166 LYS 167 0.0000

LYS 167 TRP 168 -0.0001

TRP 168 ALA 169 -0.0018

ALA 169 ASP 170 0.0001

ASP 170 ARG 171 -0.0002

ARG 171 VAL 172 0.0000

VAL 172 GLY 173 0.0001

GLY 173 ILE 174 -0.0002

ILE 174 LYS 175 0.0000

LYS 175 LEU 176 -0.0002

LEU 176 ILE 177 0.0004

ILE 177 ASP 178 -0.0004

ASP 178 PRO 179 0.0004

PRO 179 LYS 180 0.0046

LYS 180 ASN 181 -0.0002

ASN 181 LEU 182 0.0001

LEU 182 ARG 183 -0.0000

ARG 183 TYR 184 0.0001

TYR 184 ILE 185 -0.0004

ILE 185 MET 186 -0.0002

MET 186 GLU 187 0.0001

GLU 187 ASN 188 0.0000

ASN 188 LEU 189 0.0003

LEU 189 THR 190 0.0002

THR 190 MET 1 0.0004

MET 1 ASP 2 -0.0001

ASP 2 THR 3 -0.0001

THR 3 PHE 4 -0.0001

PHE 4 VAL 5 -0.0004

VAL 5 LEU 6 0.0002

LEU 6 ASP 7 0.0001

ASP 7 THR 8 -0.0002

THR 8 SER 9 -0.0003

SER 9 VAL 10 0.0001

VAL 10 PHE 11 0.0001

PHE 11 THR 12 -0.0053

THR 12 ASN 13 0.0001

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 0.0000

ASP 15 VAL 16 -0.0001

VAL 16 TYR 17 0.0002

TYR 17 HIS 18 -0.0001

HIS 18 GLN 19 -0.0001

GLN 19 PHE 20 0.0003

PHE 20 GLU 21 0.0001

GLU 21 GLU 22 -0.0001

GLU 22 ASP 23 0.0006

ASP 23 GLN 24 0.0002

GLN 24 LEU 25 -0.0003

LEU 25 GLY 26 0.0003

GLY 26 ALA 27 -0.0002

ALA 27 ILE 28 0.0001

ILE 28 GLU 29 0.0001

GLU 29 ASN 30 -0.0002

ASN 30 PHE 31 0.0000

PHE 31 ILE 32 0.0001

ILE 32 SER 33 -0.0002

SER 33 LEU 34 0.0007

LEU 34 ALA 35 0.0001

ALA 35 SER 36 0.0001

SER 36 HIS 37 0.0000

HIS 37 THR 38 0.0002

THR 38 ASN 39 -0.0001

ASN 39 ALA 40 0.0002

ALA 40 ASN 41 -0.0001

ASN 41 PHE 42 -0.0001

PHE 42 PHE 43 0.0001

PHE 43 MET 44 -0.0001

MET 44 PRO 45 -0.0001

PRO 45 THR 46 -0.0003

THR 46 SER 47 -0.0005

SER 47 VAL 48 0.0000

VAL 48 TYR 49 0.0004

TYR 49 TYR 50 0.0000

TYR 50 GLU 51 0.0002

GLU 51 PHE 52 -0.0002

PHE 52 THR 53 -0.0002

THR 53 LYS 54 0.0001

LYS 54 MET 55 -0.0000

MET 55 VAL 56 -0.0059

VAL 56 SER 57 0.0001

SER 57 LEU 58 0.0002

LEU 58 GLY 59 -0.0001

GLY 59 ASP 60 -0.0004

ASP 60 LEU 61 0.0005

LEU 61 ALA 62 -0.0003

ALA 62 PRO 63 0.0002

PRO 63 LYS 64 -0.0001

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 -0.0001

GLU 66 LEU 67 -0.0124

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 0.0005

VAL 69 ARG 70 -0.0001

ARG 70 ILE 71 0.0004

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 -0.0003

ARG 75 LYS 76 -0.0003

LYS 76 TRP 77 -0.0001

TRP 77 GLY 78 0.0146

GLY 78 LEU 79 -0.0002

LEU 79 MET 80 -0.0003

MET 80 VAL 81 0.0001

VAL 81 PRO 82 0.0001

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 -0.0003

GLU 84 PHE 85 -0.0001

PHE 85 LEU 86 -0.0000

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 -0.0002

GLU 88 PHE 89 -0.0018

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 -0.0000

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0000

VAL 93 ARG 94 -0.0004

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 -0.0000

ARG 96 ILE 97 -0.0004

ILE 97 ASN 98 0.0002

ASN 98 LYS 99 0.0002

LYS 99 GLY 100 0.0068

GLY 100 LEU 101 0.0002

LEU 101 ARG 102 -0.0000

ARG 102 ILE 103 0.0000

ILE 103 ALA 104 -0.0003

ALA 104 GLU 105 0.0003

GLU 105 GLU 106 -0.0001

GLU 106 HIS 107 0.0001

HIS 107 THR 108 -0.0001

THR 108 LEU 126 -0.0027

LEU 126 ARG 127 -0.0004

ARG 127 GLU 128 -0.0002

GLU 128 LYS 129 0.0003

LYS 129 TYR 130 -0.0004

TYR 130 ARG 131 0.0001

ARG 131 GLU 132 -0.0003

GLU 132 ALA 133 0.0000

ALA 133 LEU 134 0.0000

LEU 134 ARG 135 -0.0001

ARG 135 ALA 136 -0.0003

ALA 136 GLY 137 0.0156

GLY 137 ILE 138 0.0003

ILE 138 ILE 139 0.0002

ILE 139 ASP 140 0.0000

ASP 140 SER 141 -0.0001

SER 141 LYS 142 -0.0001

LYS 142 GLU 143 0.0003

GLU 143 ASP 144 -0.0002

ASP 144 VAL 145 -0.0003

VAL 145 ASP 146 -0.0002

ASP 146 VAL 147 0.0000

VAL 147 LEU 148 -0.0054

LEU 148 LEU 149 0.0001

LEU 149 LEU 150 -0.0000

LEU 150 SER 151 -0.0000

SER 151 TYR 152 -0.0001

TYR 152 GLU 153 -0.0000

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 -0.0001

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 -0.0002

ILE 157 LEU 158 0.0001

LEU 158 VAL 159 -0.0107

VAL 159 SER 160 -0.0002

SER 160 GLY 161 0.0001

GLY 161 ASP 162 0.0001

ASP 162 GLU 163 -0.0003

GLU 163 GLY 164 -0.0002

GLY 164 LEU 165 0.0001

LEU 165 ARG 166 0.0000

ARG 166 LYS 167 -0.0001

LYS 167 TRP 168 0.0003

TRP 168 ALA 169 0.0001

ALA 169 ASP 170 0.0103

ASP 170 ARG 171 0.0003

ARG 171 VAL 172 -0.0000

VAL 172 GLY 173 -0.0000

GLY 173 ILE 174 -0.0004

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 0.0000

LEU 176 ILE 177 -0.0002

ILE 177 ASP 178 -0.0004

ASP 178 PRO 179 0.0002

PRO 179 LYS 180 -0.0002

LYS 180 ASN 181 0.0074

ASN 181 LEU 182 -0.0004

LEU 182 ARG 183 -0.0003

ARG 183 TYR 184 -0.0004

TYR 184 ILE 185 -0.0001

ILE 185 MET 186 0.0004

MET 186 GLU 187 -0.0000

GLU 187 ASN 188 -0.0003

ASN 188 LEU 189 -0.0001

LEU 189 THR 190 -0.0002

THR 190 LYS 191 0.0002

LYS 191 VAL 192 0.0039

VAL 192 GLY 193 0.0000

GLY 193 ARG 194 0.0003

ARG 194 MET 1 0.0123

MET 1 ASP 2 0.0001

ASP 2 THR 3 -0.0001

THR 3 PHE 4 -0.0003

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 -0.0002

LEU 6 ASP 7 0.0002

ASP 7 THR 8 0.0000

THR 8 SER 9 0.0002

SER 9 VAL 10 0.0002

VAL 10 PHE 11 0.0000

PHE 11 THR 12 0.0010

THR 12 ASN 13 -0.0004

ASN 13 PRO 14 0.0000

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 -0.0003

VAL 16 TYR 17 0.0004

TYR 17 HIS 18 -0.0003

HIS 18 GLN 19 -0.0001

GLN 19 PHE 20 -0.0001

PHE 20 GLU 21 -0.0001

GLU 21 GLU 22 -0.0000

GLU 22 ASP 23 0.0021

ASP 23 GLN 24 -0.0004

GLN 24 LEU 25 -0.0000

LEU 25 GLY 26 0.0003

GLY 26 ALA 27 -0.0001

ALA 27 ILE 28 0.0002

ILE 28 GLU 29 -0.0000

GLU 29 ASN 30 0.0000

ASN 30 PHE 31 0.0002

PHE 31 ILE 32 0.0004

ILE 32 SER 33 -0.0002

SER 33 LEU 34 0.0019

LEU 34 ALA 35 0.0004

ALA 35 SER 36 0.0002

SER 36 HIS 37 -0.0002

HIS 37 THR 38 -0.0000

THR 38 ASN 39 -0.0001

ASN 39 ALA 40 0.0004

ALA 40 ASN 41 -0.0001

ASN 41 PHE 42 0.0003

PHE 42 PHE 43 0.0000

PHE 43 MET 44 0.0003

MET 44 PRO 45 -0.0058

PRO 45 THR 46 -0.0002

THR 46 SER 47 0.0002

SER 47 VAL 48 -0.0004

VAL 48 TYR 49 0.0002

TYR 49 TYR 50 -0.0004

TYR 50 GLU 51 -0.0002

GLU 51 PHE 52 0.0001

PHE 52 THR 53 0.0001

THR 53 LYS 54 -0.0003

LYS 54 MET 55 -0.0000

MET 55 VAL 56 -0.0046

VAL 56 SER 57 0.0002

SER 57 LEU 58 -0.0003

LEU 58 GLY 59 0.0002

GLY 59 ASP 60 0.0000

ASP 60 LEU 61 0.0001

LEU 61 ALA 62 -0.0001

ALA 62 PRO 63 0.0001

PRO 63 LYS 64 0.0003

LYS 64 PHE 65 -0.0003

PHE 65 GLU 66 0.0001

GLU 66 LEU 67 -0.0008

LEU 67 VAL 68 -0.0000

VAL 68 VAL 69 0.0000

VAL 69 ARG 70 -0.0002

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 0.0001

ARG 72 SER 73 0.0002

SER 73 PRO 74 -0.0004

PRO 74 ARG 75 0.0002

ARG 75 LYS 76 -0.0002

LYS 76 TRP 77 0.0001

TRP 77 GLY 78 0.0219

GLY 78 LEU 79 0.0001

LEU 79 MET 80 -0.0002

MET 80 VAL 81 0.0001

VAL 81 PRO 82 -0.0002

PRO 82 ALA 83 -0.0003

ALA 83 GLU 84 -0.0002

GLU 84 PHE 85 -0.0002

PHE 85 LEU 86 -0.0001

LEU 86 TYR 87 0.0000

TYR 87 GLU 88 -0.0003

GLU 88 PHE 89 0.0045

PHE 89 ILE 90 0.0002

ILE 90 GLU 91 0.0002

GLU 91 GLU 92 -0.0002

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0001

ILE 97 ASN 98 0.0003

ASN 98 LYS 99 -0.0002

LYS 99 GLY 100 -0.0011

GLY 100 LEU 101 -0.0000

LEU 101 ARG 102 -0.0000

ARG 102 ILE 103 -0.0001

ILE 103 ALA 104 0.0004

ALA 104 GLU 105 0.0002

GLU 105 GLU 106 0.0002

GLU 106 HIS 107 -0.0003

HIS 107 ARG 125 0.0002

ARG 125 LEU 126 -0.0000

LEU 126 ARG 127 -0.0001

ARG 127 GLU 128 0.0001

GLU 128 LYS 129 -0.0004

LYS 129 TYR 130 0.0000

TYR 130 ARG 131 0.0001

ARG 131 GLU 132 0.0001

GLU 132 ALA 133 -0.0005

ALA 133 LEU 134 0.0003

LEU 134 ARG 135 -0.0001

ARG 135 ALA 136 -0.0194

ALA 136 GLY 137 -0.0002

GLY 137 ILE 138 -0.0000

ILE 138 ILE 139 -0.0001

ILE 139 ASP 140 0.0001

ASP 140 SER 141 -0.0001

SER 141 LYS 142 0.0001

LYS 142 GLU 143 -0.0003

GLU 143 ASP 144 -0.0000

ASP 144 VAL 145 -0.0002

VAL 145 ASP 146 0.0002

ASP 146 VAL 147 -0.0057

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 0.0000

LEU 149 LEU 150 0.0001

LEU 150 SER 151 0.0000

SER 151 TYR 152 0.0000

TYR 152 GLU 153 0.0004

GLU 153 LEU 154 -0.0003

LEU 154 ASP 155 0.0000

ASP 155 ALA 156 -0.0001

ALA 156 ILE 157 -0.0001

ILE 157 LEU 158 0.0041

LEU 158 VAL 159 -0.0003

VAL 159 SER 160 -0.0002

SER 160 GLY 161 0.0000

GLY 161 ASP 162 -0.0000

ASP 162 GLU 163 -0.0002

GLU 163 GLY 164 0.0002

GLY 164 LEU 165 -0.0001

LEU 165 ARG 166 0.0001

ARG 166 LYS 167 -0.0001

LYS 167 TRP 168 0.0000

TRP 168 ALA 169 -0.0005

ALA 169 ASP 170 0.0004

ASP 170 ARG 171 0.0002

ARG 171 VAL 172 -0.0001

VAL 172 GLY 173 0.0004

GLY 173 ILE 174 -0.0001

ILE 174 LYS 175 0.0001

LYS 175 LEU 176 0.0001

LEU 176 ILE 177 0.0001

ILE 177 ASP 178 -0.0002

ASP 178 PRO 179 -0.0004

PRO 179 LYS 180 0.0032

LYS 180 ASN 181 0.0003

ASN 181 LEU 182 0.0003

LEU 182 ARG 183 0.0000

ARG 183 TYR 184 0.0001

TYR 184 ILE 185 -0.0001

ILE 185 MET 186 0.0003

MET 186 GLU 187 0.0000

GLU 187 ASN 188 -0.0004

ASN 188 LEU 189 0.0001

LEU 189 THR 190 -0.0003

THR 190 MET 1 -0.0545

MET 1 ASP 2 -0.0002

ASP 2 THR 3 0.0000

THR 3 PHE 4 0.0000

PHE 4 VAL 5 0.0000

VAL 5 LEU 6 0.0005

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0001

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0002

PHE 11 THR 12 -0.0004

THR 12 ASN 13 -0.0002

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 0.0000

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0000

TYR 17 HIS 18 -0.0004

HIS 18 GLN 19 0.0001

GLN 19 PHE 20 -0.0002

PHE 20 GLU 21 -0.0003

GLU 21 GLU 22 -0.0001

GLU 22 ASP 23 -0.0058

ASP 23 GLN 24 -0.0000

GLN 24 LEU 25 0.0000

LEU 25 GLY 26 0.0001

GLY 26 ALA 27 -0.0000

ALA 27 ILE 28 -0.0002

ILE 28 GLU 29 -0.0002

GLU 29 ASN 30 -0.0000

ASN 30 PHE 31 -0.0003

PHE 31 ILE 32 0.0004

ILE 32 SER 33 0.0001

SER 33 LEU 34 0.0130

LEU 34 ALA 35 0.0004

ALA 35 SER 36 -0.0003

SER 36 HIS 37 -0.0001

HIS 37 THR 38 0.0002

THR 38 ASN 39 -0.0001

ASN 39 ALA 40 -0.0001

ALA 40 ASN 41 0.0000

ASN 41 PHE 42 -0.0001

PHE 42 PHE 43 -0.0001

PHE 43 MET 44 -0.0002

MET 44 PRO 45 0.0012

PRO 45 THR 46 0.0000

THR 46 SER 47 -0.0001

SER 47 VAL 48 0.0000

VAL 48 TYR 49 -0.0002

TYR 49 TYR 50 -0.0000

TYR 50 GLU 51 -0.0002

GLU 51 PHE 52 -0.0000

PHE 52 THR 53 0.0001

THR 53 LYS 54 0.0002

LYS 54 MET 55 -0.0003

MET 55 VAL 56 -0.0020

VAL 56 SER 57 -0.0000

SER 57 LEU 58 0.0000

LEU 58 GLY 59 0.0001

GLY 59 ASP 60 0.0000

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 -0.0000

ALA 62 PRO 63 0.0000

PRO 63 LYS 64 -0.0004

LYS 64 PHE 65 -0.0002

PHE 65 GLU 66 -0.0001

GLU 66 LEU 67 -0.0007

LEU 67 VAL 68 0.0000

VAL 68 VAL 69 -0.0001

VAL 69 ARG 70 -0.0003

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 0.0002

ARG 72 SER 73 -0.0000

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 -0.0003

ARG 75 LYS 76 0.0001

LYS 76 TRP 77 0.0002

TRP 77 GLY 78 0.0079

GLY 78 LEU 79 -0.0003

LEU 79 MET 80 0.0001

MET 80 VAL 81 0.0000

VAL 81 PRO 82 0.0000

PRO 82 ALA 83 0.0002

ALA 83 GLU 84 -0.0000

GLU 84 PHE 85 -0.0001

PHE 85 LEU 86 0.0001

LEU 86 TYR 87 -0.0000

TYR 87 GLU 88 0.0002

GLU 88 PHE 89 0.0045

PHE 89 ILE 90 -0.0003

ILE 90 GLU 91 0.0004

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 0.0003

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 -0.0002

ARG 96 ILE 97 0.0002

ILE 97 ASN 98 -0.0001

ASN 98 LYS 99 0.0003

LYS 99 GLY 100 -0.0005

GLY 100 LEU 101 -0.0001

LEU 101 ARG 102 -0.0003

ARG 102 ILE 103 -0.0001

ILE 103 ALA 104 -0.0002

ALA 104 GLU 105 -0.0003

GLU 105 GLU 106 0.0002

GLU 106 HIS 107 -0.0003

HIS 107 THR 108 0.0001

THR 108 LEU 126 0.0006

LEU 126 ARG 127 -0.0002

ARG 127 GLU 128 0.0001

GLU 128 LYS 129 -0.0003

LYS 129 TYR 130 0.0002

TYR 130 ARG 131 -0.0000

ARG 131 GLU 132 0.0001

GLU 132 ALA 133 0.0002

ALA 133 LEU 134 0.0002

LEU 134 ARG 135 0.0002

ARG 135 ALA 136 -0.0001

ALA 136 GLY 137 -0.0001

GLY 137 ILE 138 0.0002

ILE 138 ILE 139 -0.0000

ILE 139 ASP 140 0.0002

ASP 140 SER 141 -0.0003

SER 141 LYS 142 -0.0001

LYS 142 GLU 143 -0.0001

GLU 143 ASP 144 0.0000

ASP 144 VAL 145 0.0001

VAL 145 ASP 146 0.0000

ASP 146 VAL 147 -0.0002

VAL 147 LEU 148 0.0030

LEU 148 LEU 149 0.0000

LEU 149 LEU 150 0.0002

LEU 150 SER 151 0.0003

SER 151 TYR 152 -0.0003

TYR 152 GLU 153 -0.0003

GLU 153 LEU 154 -0.0002

LEU 154 ASP 155 0.0004

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 0.0000

ILE 157 LEU 158 -0.0001

LEU 158 VAL 159 -0.0030

VAL 159 SER 160 0.0002

SER 160 GLY 161 -0.0001

GLY 161 ASP 162 0.0003

ASP 162 GLU 163 -0.0003

GLU 163 GLY 164 0.0001

GLY 164 LEU 165 0.0002

LEU 165 ARG 166 -0.0000

ARG 166 LYS 167 0.0000

LYS 167 TRP 168 0.0005

TRP 168 ALA 169 -0.0002

ALA 169 ASP 170 -0.0018

ASP 170 ARG 171 -0.0001

ARG 171 VAL 172 0.0001

VAL 172 GLY 173 -0.0002

GLY 173 ILE 174 -0.0001

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 0.0002

LEU 176 ILE 177 -0.0000

ILE 177 ASP 178 -0.0003

ASP 178 PRO 179 -0.0003

PRO 179 LYS 180 0.0003

LYS 180 ASN 181 0.0058

ASN 181 LEU 182 0.0001

LEU 182 ARG 183 -0.0001

ARG 183 TYR 184 -0.0002

TYR 184 ILE 185 0.0000

ILE 185 MET 186 0.0003

MET 186 GLU 187 0.0002

GLU 187 ASN 188 0.0003

ASN 188 LEU 189 0.0004

LEU 189 THR 190 -0.0001

THR 190 LYS 191 0.0001

LYS 191 VAL 192 0.0067

VAL 192 GLY 193 -0.0002

GLY 193 ARG 194 -0.0005

ARG 194 MET 1 -0.0042

MET 1 ASP 2 -0.0002

ASP 2 THR 3 0.0001

THR 3 PHE 4 -0.0001

PHE 4 VAL 5 -0.0004

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 -0.0003

THR 8 SER 9 -0.0003

SER 9 VAL 10 -0.0003

VAL 10 PHE 11 0.0000

PHE 11 THR 12 0.0034

THR 12 ASN 13 -0.0000

ASN 13 PRO 14 -0.0002

PRO 14 ASP 15 0.0002

ASP 15 VAL 16 -0.0002

VAL 16 TYR 17 0.0001

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0002

GLN 19 PHE 20 0.0002

PHE 20 GLU 21 0.0005

GLU 21 GLU 22 -0.0003

GLU 22 ASP 23 -0.0025

ASP 23 GLN 24 -0.0001

GLN 24 LEU 25 0.0003

LEU 25 GLY 26 -0.0000

GLY 26 ALA 27 -0.0001

ALA 27 ILE 28 0.0003

ILE 28 GLU 29 0.0001

GLU 29 ASN 30 -0.0004

ASN 30 PHE 31 0.0003

PHE 31 ILE 32 -0.0001

ILE 32 SER 33 0.0000

SER 33 LEU 34 -0.0050

LEU 34 ALA 35 -0.0001

ALA 35 SER 36 -0.0003

SER 36 HIS 37 -0.0001

HIS 37 THR 38 0.0001

THR 38 ASN 39 0.0001

ASN 39 ALA 40 0.0002

ALA 40 ASN 41 -0.0001

ASN 41 PHE 42 -0.0001

PHE 42 PHE 43 -0.0001

PHE 43 MET 44 0.0001

MET 44 PRO 45 -0.0053

PRO 45 THR 46 -0.0002

THR 46 SER 47 0.0002

SER 47 VAL 48 -0.0005

VAL 48 TYR 49 0.0000

TYR 49 TYR 50 0.0002

TYR 50 GLU 51 0.0001

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 -0.0001

THR 53 LYS 54 0.0001

LYS 54 MET 55 -0.0000

MET 55 VAL 56 -0.0036

VAL 56 SER 57 0.0002

SER 57 LEU 58 0.0004

LEU 58 GLY 59 -0.0003

GLY 59 ASP 60 0.0003

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 0.0000

ALA 62 PRO 63 0.0001

PRO 63 LYS 64 0.0003

LYS 64 PHE 65 0.0003

PHE 65 GLU 66 -0.0000

GLU 66 LEU 67 0.0003

LEU 67 VAL 68 0.0004

VAL 68 VAL 69 -0.0001

VAL 69 ARG 70 0.0003

ARG 70 ILE 71 -0.0003

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 0.0003

ARG 75 LYS 76 -0.0001

LYS 76 TRP 77 0.0003

TRP 77 GLY 78 0.0173

GLY 78 LEU 79 -0.0000

LEU 79 MET 80 -0.0000

MET 80 VAL 81 0.0000

VAL 81 PRO 82 -0.0001

PRO 82 ALA 83 -0.0001

ALA 83 GLU 84 0.0002

GLU 84 PHE 85 -0.0002

PHE 85 LEU 86 0.0000

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 -0.0003

GLU 88 PHE 89 -0.0083

PHE 89 ILE 90 0.0002

ILE 90 GLU 91 -0.0001

GLU 91 GLU 92 0.0000

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 -0.0000

TYR 95 ARG 96 -0.0003

ARG 96 ILE 97 0.0002

ILE 97 ASN 98 -0.0003

ASN 98 LYS 99 -0.0001

LYS 99 GLY 100 0.0013

GLY 100 LEU 101 -0.0001

LEU 101 ARG 102 -0.0001

ARG 102 ILE 103 -0.0004

ILE 103 ALA 104 -0.0001

ALA 104 GLU 105 0.0004

GLU 105 GLU 106 -0.0003

GLU 106 HIS 107 -0.0002

HIS 107 ARG 125 0.0002

ARG 125 LEU 126 0.0004

LEU 126 ARG 127 -0.0003

ARG 127 GLU 128 -0.0001

GLU 128 LYS 129 0.0003

LYS 129 TYR 130 -0.0005

TYR 130 ARG 131 0.0001

ARG 131 GLU 132 0.0003

GLU 132 ALA 133 -0.0001

ALA 133 LEU 134 0.0002

LEU 134 ARG 135 0.0001

ARG 135 ALA 136 0.0051

ALA 136 GLY 137 -0.0001

GLY 137 ILE 138 -0.0002

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 0.0004

ASP 140 SER 141 0.0000

SER 141 LYS 142 -0.0002

LYS 142 GLU 143 0.0004

GLU 143 ASP 144 0.0002

ASP 144 VAL 145 0.0004

VAL 145 ASP 146 0.0001

ASP 146 VAL 147 -0.0032

VAL 147 LEU 148 0.0000

LEU 148 LEU 149 -0.0003

LEU 149 LEU 150 -0.0003

LEU 150 SER 151 -0.0002

SER 151 TYR 152 0.0001

TYR 152 GLU 153 -0.0002

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 -0.0000

ASP 155 ALA 156 -0.0000

ALA 156 ILE 157 0.0001

ILE 157 LEU 158 0.0017

LEU 158 VAL 159 -0.0000

VAL 159 SER 160 -0.0002

SER 160 GLY 161 0.0000

GLY 161 ASP 162 0.0001

ASP 162 GLU 163 0.0001

GLU 163 GLY 164 -0.0001

GLY 164 LEU 165 -0.0000

LEU 165 ARG 166 -0.0001

ARG 166 LYS 167 -0.0000

LYS 167 TRP 168 0.0001

TRP 168 ALA 169 0.0027

ALA 169 ASP 170 -0.0002

ASP 170 ARG 171 -0.0001

ARG 171 VAL 172 0.0002

VAL 172 GLY 173 -0.0001

GLY 173 ILE 174 -0.0001

ILE 174 LYS 175 -0.0002

LYS 175 LEU 176 0.0003

LEU 176 ILE 177 -0.0003

ILE 177 ASP 178 -0.0001

ASP 178 PRO 179 0.0004

PRO 179 LYS 180 -0.0043

LYS 180 ASN 181 -0.0003

ASN 181 LEU 182 -0.0002

LEU 182 ARG 183 0.0000

ARG 183 TYR 184 -0.0001

TYR 184 ILE 185 0.0001

ILE 185 MET 186 -0.0003

MET 186 GLU 187 0.0003

GLU 187 ASN 188 0.0001

ASN 188 LEU 189 0.0002

LEU 189 THR 190 0.0002

THR 190 MET 1 0.0178

MET 1 ASP 2 0.0003

ASP 2 THR 3 0.0002

THR 3 PHE 4 -0.0000

PHE 4 VAL 5 -0.0001

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 -0.0003

THR 8 SER 9 -0.0002

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 -0.0002

PHE 11 THR 12 0.0002

THR 12 ASN 13 0.0001

ASN 13 PRO 14 -0.0002

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0002

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0000

GLN 19 PHE 20 -0.0001

PHE 20 GLU 21 0.0003

GLU 21 GLU 22 -0.0004

GLU 22 ASP 23 0.0017

ASP 23 GLN 24 0.0003

GLN 24 LEU 25 -0.0002

LEU 25 GLY 26 0.0004

GLY 26 ALA 27 0.0002

ALA 27 ILE 28 0.0002

ILE 28 GLU 29 0.0002

GLU 29 ASN 30 -0.0004

ASN 30 PHE 31 0.0001

PHE 31 ILE 32 -0.0000

ILE 32 SER 33 0.0001

SER 33 LEU 34 -0.0039

LEU 34 ALA 35 0.0001

ALA 35 SER 36 -0.0002

SER 36 HIS 37 0.0001

HIS 37 THR 38 0.0000

THR 38 ASN 39 0.0001

ASN 39 ALA 40 -0.0002

ALA 40 ASN 41 0.0004

ASN 41 PHE 42 -0.0002

PHE 42 PHE 43 -0.0002

PHE 43 MET 44 -0.0000

MET 44 PRO 45 -0.0051

PRO 45 THR 46 -0.0000

THR 46 SER 47 0.0003

SER 47 VAL 48 0.0003

VAL 48 TYR 49 0.0003

TYR 49 TYR 50 0.0004

TYR 50 GLU 51 -0.0003

GLU 51 PHE 52 0.0000

PHE 52 THR 53 0.0000

THR 53 LYS 54 0.0000

LYS 54 MET 55 0.0004

MET 55 VAL 56 -0.0044

VAL 56 SER 57 0.0001

SER 57 LEU 58 0.0003

LEU 58 GLY 59 0.0000

GLY 59 ASP 60 0.0002

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 -0.0002

ALA 62 PRO 63 -0.0001

PRO 63 LYS 64 -0.0001

LYS 64 PHE 65 0.0001

PHE 65 GLU 66 -0.0002

GLU 66 LEU 67 0.0008

LEU 67 VAL 68 0.0003

VAL 68 VAL 69 -0.0003

VAL 69 ARG 70 0.0003

ARG 70 ILE 71 -0.0002

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 0.0002

SER 73 PRO 74 0.0001

PRO 74 ARG 75 -0.0000

ARG 75 LYS 76 -0.0004

LYS 76 TRP 77 -0.0000

TRP 77 GLY 78 0.0128

GLY 78 LEU 79 0.0001

LEU 79 MET 80 0.0003

MET 80 VAL 81 -0.0001

VAL 81 PRO 82 -0.0002

PRO 82 ALA 83 0.0002

ALA 83 GLU 84 0.0000

GLU 84 PHE 85 -0.0003

PHE 85 LEU 86 -0.0002

LEU 86 TYR 87 -0.0006

TYR 87 GLU 88 0.0001

GLU 88 PHE 89 -0.0080

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 -0.0003

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 0.0005

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0001

ILE 97 ASN 98 0.0001

ASN 98 LYS 99 0.0001

LYS 99 GLY 100 0.0093

GLY 100 LEU 101 0.0000

LEU 101 ARG 102 -0.0002

ARG 102 ILE 103 0.0002

ILE 103 ALA 104 -0.0001

ALA 104 GLU 105 -0.0001

GLU 105 GLU 106 0.0002

GLU 106 HIS 107 0.0004

HIS 107 THR 108 0.0001

THR 108 LEU 126 -0.0019

LEU 126 ARG 127 0.0001

ARG 127 GLU 128 -0.0000

GLU 128 LYS 129 -0.0002

LYS 129 TYR 130 0.0001

TYR 130 ARG 131 0.0000

ARG 131 GLU 132 0.0002

GLU 132 ALA 133 0.0001

ALA 133 LEU 134 0.0000

LEU 134 ARG 135 -0.0003

ARG 135 ALA 136 -0.0002

ALA 136 GLY 137 0.0164

GLY 137 ILE 138 0.0000

ILE 138 ILE 139 0.0002

ILE 139 ASP 140 -0.0000

ASP 140 SER 141 -0.0001

SER 141 LYS 142 0.0000

LYS 142 GLU 143 -0.0000

GLU 143 ASP 144 0.0001

ASP 144 VAL 145 -0.0000

VAL 145 ASP 146 -0.0004

ASP 146 VAL 147 0.0002

VAL 147 LEU 148 -0.0028

LEU 148 LEU 149 -0.0002

LEU 149 LEU 150 -0.0000

LEU 150 SER 151 -0.0002

SER 151 TYR 152 0.0002

TYR 152 GLU 153 0.0003

GLU 153 LEU 154 0.0001

LEU 154 ASP 155 0.0002

ASP 155 ALA 156 0.0005

ALA 156 ILE 157 -0.0005

ILE 157 LEU 158 0.0000

LEU 158 VAL 159 -0.0215

VAL 159 SER 160 0.0002

SER 160 GLY 161 0.0001

GLY 161 ASP 162 0.0000

ASP 162 GLU 163 -0.0003

GLU 163 GLY 164 -0.0002

GLY 164 LEU 165 0.0003

LEU 165 ARG 166 0.0001

ARG 166 LYS 167 0.0004

LYS 167 TRP 168 -0.0001

TRP 168 ALA 169 0.0001

ALA 169 ASP 170 0.0161

ASP 170 ARG 171 0.0002

ARG 171 VAL 172 -0.0002

VAL 172 GLY 173 0.0002

GLY 173 ILE 174 -0.0003

ILE 174 LYS 175 -0.0001

LYS 175 LEU 176 0.0001

LEU 176 ILE 177 -0.0002

ILE 177 ASP 178 0.0002

ASP 178 PRO 179 -0.0001

PRO 179 LYS 180 -0.0001

LYS 180 ASN 181 -0.0028

ASN 181 LEU 182 0.0000

LEU 182 ARG 183 -0.0000

ARG 183 TYR 184 -0.0002

TYR 184 ILE 185 0.0002

ILE 185 MET 186 -0.0003

MET 186 GLU 187 -0.0005

GLU 187 ASN 188 -0.0000

ASN 188 LEU 189 0.0002

LEU 189 THR 190 0.0001

THR 190 LYS 191 0.0001

LYS 191 VAL 192 -0.0106

VAL 192 GLY 193 0.0001

GLY 193 ARG 194 -0.0001

ARG 194 MET 1 -0.0045

MET 1 ASP 2 0.0000

ASP 2 THR 3 -0.0001

THR 3 PHE 4 0.0001

PHE 4 VAL 5 -0.0000

VAL 5 LEU 6 0.0000

LEU 6 ASP 7 -0.0004

ASP 7 THR 8 0.0003

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0000

PHE 11 THR 12 0.0095

THR 12 ASN 13 -0.0003

ASN 13 PRO 14 -0.0003

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 -0.0000

VAL 16 TYR 17 0.0001

TYR 17 HIS 18 0.0000

HIS 18 GLN 19 0.0003

GLN 19 PHE 20 -0.0002

PHE 20 GLU 21 0.0002

GLU 21 GLU 22 -0.0003

GLU 22 ASP 23 -0.0017

ASP 23 GLN 24 -0.0004

GLN 24 LEU 25 0.0001

LEU 25 GLY 26 0.0002

GLY 26 ALA 27 -0.0001

ALA 27 ILE 28 -0.0003

ILE 28 GLU 29 0.0002

GLU 29 ASN 30 0.0004

ASN 30 PHE 31 0.0005

PHE 31 ILE 32 0.0003

ILE 32 SER 33 0.0000

SER 33 LEU 34 0.0021

LEU 34 ALA 35 -0.0002

ALA 35 SER 36 0.0002

SER 36 HIS 37 0.0002

HIS 37 THR 38 -0.0003

THR 38 ASN 39 0.0001

ASN 39 ALA 40 -0.0003

ALA 40 ASN 41 0.0004

ASN 41 PHE 42 -0.0001

PHE 42 PHE 43 0.0003

PHE 43 MET 44 -0.0000

MET 44 PRO 45 -0.0034

PRO 45 THR 46 -0.0003

THR 46 SER 47 0.0001

SER 47 VAL 48 0.0006

VAL 48 TYR 49 -0.0002

TYR 49 TYR 50 -0.0001

TYR 50 GLU 51 -0.0000

GLU 51 PHE 52 -0.0002

PHE 52 THR 53 0.0004

THR 53 LYS 54 -0.0004

LYS 54 MET 55 0.0002

MET 55 VAL 56 -0.0014

VAL 56 SER 57 0.0001

SER 57 LEU 58 -0.0004

LEU 58 GLY 59 0.0001

GLY 59 ASP 60 -0.0000

ASP 60 LEU 61 -0.0003

LEU 61 ALA 62 -0.0001

ALA 62 PRO 63 -0.0002

PRO 63 LYS 64 0.0000

LYS 64 PHE 65 0.0000

PHE 65 GLU 66 -0.0000

GLU 66 LEU 67 0.0037

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 -0.0001

VAL 69 ARG 70 0.0001

ARG 70 ILE 71 -0.0002

ILE 71 ARG 72 0.0003

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0000

PRO 74 ARG 75 -0.0003

ARG 75 LYS 76 0.0000

LYS 76 TRP 77 -0.0001

TRP 77 GLY 78 -0.0040

GLY 78 LEU 79 0.0001

LEU 79 MET 80 0.0002

MET 80 VAL 81 -0.0003

VAL 81 PRO 82 0.0002

PRO 82 ALA 83 -0.0000

ALA 83 GLU 84 0.0003

GLU 84 PHE 85 0.0003

PHE 85 LEU 86 0.0004

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 -0.0077

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 -0.0000

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0003

VAL 93 ARG 94 0.0002

ARG 94 TYR 95 0.0002

TYR 95 ARG 96 0.0004

ARG 96 ILE 97 0.0000

ILE 97 ASN 98 0.0004

ASN 98 LYS 99 -0.0000

LYS 99 GLY 100 -0.0057

GLY 100 LEU 101 -0.0003

LEU 101 ARG 102 0.0004

ARG 102 ILE 103 0.0001

ILE 103 ALA 104 0.0002

ALA 104 GLU 105 0.0001

GLU 105 GLU 106 0.0001

GLU 106 HIS 107 -0.0000

HIS 107 ARG 125 -0.0014

ARG 125 LEU 126 0.0000

LEU 126 ARG 127 -0.0004

ARG 127 GLU 128 -0.0001

GLU 128 LYS 129 -0.0001

LYS 129 TYR 130 -0.0000

TYR 130 ARG 131 0.0002

ARG 131 GLU 132 -0.0000

GLU 132 ALA 133 0.0001

ALA 133 LEU 134 -0.0002

LEU 134 ARG 135 -0.0000

ARG 135 ALA 136 0.0071

ALA 136 GLY 137 -0.0003

GLY 137 ILE 138 0.0002

ILE 138 ILE 139 -0.0000

ILE 139 ASP 140 0.0002

ASP 140 SER 141 -0.0004

SER 141 LYS 142 0.0005

LYS 142 GLU 143 0.0001

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 -0.0004

VAL 145 ASP 146 -0.0001

ASP 146 VAL 147 -0.0078

VAL 147 LEU 148 -0.0003

LEU 148 LEU 149 -0.0001

LEU 149 LEU 150 -0.0002

LEU 150 SER 151 0.0001

SER 151 TYR 152 0.0003

TYR 152 GLU 153 -0.0001

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 -0.0004

ASP 155 ALA 156 -0.0001

ALA 156 ILE 157 0.0000

ILE 157 LEU 158 0.0069

LEU 158 VAL 159 -0.0001

VAL 159 SER 160 0.0002

SER 160 GLY 161 -0.0001

GLY 161 ASP 162 -0.0000

ASP 162 GLU 163 -0.0001

GLU 163 GLY 164 0.0001

GLY 164 LEU 165 0.0001

LEU 165 ARG 166 -0.0000

ARG 166 LYS 167 0.0002

LYS 167 TRP 168 0.0001

TRP 168 ALA 169 0.0059

ALA 169 ASP 170 -0.0001

ASP 170 ARG 171 0.0001

ARG 171 VAL 172 -0.0002

VAL 172 GLY 173 -0.0000

GLY 173 ILE 174 0.0000

ILE 174 LYS 175 0.0001

LYS 175 LEU 176 -0.0002

LEU 176 ILE 177 -0.0003

ILE 177 ASP 178 0.0001

ASP 178 PRO 179 0.0001

PRO 179 LYS 180 -0.0053

LYS 180 ASN 181 -0.0001

ASN 181 LEU 182 0.0001

LEU 182 ARG 183 -0.0001

ARG 183 TYR 184 -0.0001

TYR 184 ILE 185 -0.0000

ILE 185 MET 186 0.0003

MET 186 GLU 187 -0.0000

GLU 187 ASN 188 0.0004

ASN 188 LEU 189 -0.0000

LEU 189 THR 190 -0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** ***

CA strain for 22121317404857062

--- normal mode 8 ---

Should you encounter any unexpected behaviour,
please let us know.

* *