Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *

CA strain for 22101813491974862

--- normal mode 30 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
ASN 989 LYS 990 0.0481

LYS 990 ALA 991 0.0051

ALA 991 HIS 992 0.0466

HIS 992 ARG 993 0.0193

ARG 993 GLN 994 0.0371

GLN 994 ARG 995 0.0163

ARG 995 VAL 996 0.0423

VAL 996 HIS 997 0.0266

HIS 997 PRO 998 0.0463

PRO 998 PRO 999 0.0298

PRO 999 HIS 1000 0.0162

HIS 1000 ASP 1001 0.0373

ASP 1001 LEU 1002 0.0119

LEU 1002 LEU 1003 0.0448

LEU 1003 GLY 1004 0.0128

GLY 1004 SER 1005 -0.2488

SER 1005 LEU 1006 0.0185

LEU 1006 ILE 1007 0.0203

ILE 1007 VAL 1008 0.0127

VAL 1008 GLY 1009 0.0200

GLY 1009 ARG 1010 0.0001

ARG 1010 ASP 1011 0.0140

ASP 1011 LEU 1012 0.0207

LEU 1012 ARG 1013 0.0022

ARG 1013 GLU 1014 0.0208

GLU 1014 PRO 1015 0.0113

PRO 1015 THR 1016 0.0201

THR 1016 TRP 1017 0.0164

TRP 1017 ARG 1018 0.0166

ARG 1018 HIS 1019 0.0210

HIS 1019 PHE 1020 0.0168

PHE 1020 ILE 1021 0.1157

ILE 1021 ARG 1022 0.0533

ARG 1022 VAL 1023 0.0091

VAL 1023 GLN 1024 0.0501

GLN 1024 ASP 1025 0.0427

ASP 1025 ILE 1026 0.0262

ILE 1026 PRO 1027 0.0164

PRO 1027 TRP 1028 0.0356

TRP 1028 ILE 1029 0.0556

ILE 1029 ARG 1030 0.0369

ARG 1030 ASP 1031 0.0249

ASP 1031 HIS 1032 0.0561

HIS 1032 VAL 1033 0.0517

VAL 1033 VAL 1034 0.0542

VAL 1034 GLN 1035 0.0494

GLN 1035 SER 1036 0.0542

SER 1036 ALA 1037 -0.0338

ALA 1037 LEU 1038 0.0241

LEU 1038 VAL 1039 0.0347

VAL 1039 TYR 1040 0.0178

TYR 1040 PRO 1041 0.0342

PRO 1041 GLY 1042 0.0373

GLY 1042 ALA 1043 0.0387

ALA 1043 GLY 1044 0.0209

GLY 1044 PHE 1045 0.0278

PHE 1045 ILE 1046 0.0400

ILE 1046 CYS 1047 0.0381

CYS 1047 MET 1048 0.0188

MET 1048 ALA 1049 0.0348

ALA 1049 MET 1050 0.0401

MET 1050 GLU 1051 0.0323

GLU 1051 ALA 1052 0.0221

ALA 1052 MET 1053 0.1674

MET 1053 VAL 1054 0.0217

VAL 1054 GLN 1055 0.0132

GLN 1055 LEU 1056 0.0138

LEU 1056 HIS 1057 0.0219

HIS 1057 GLU 1058 0.0212

GLU 1058 LEU 1059 0.0099

LEU 1059 ARG 1060 0.0181

ARG 1060 ASP 1061 0.0213

ASP 1061 SER 1062 0.0177

SER 1062 GLN 1063 0.0204

GLN 1063 SER 1064 0.0027

SER 1064 ARG 1065 0.0181

ARG 1065 LYS 1066 0.0012

LYS 1066 VAL 1067 0.0145

VAL 1067 ALA 1068 0.0106

ALA 1068 GLY 1069 0.1243

GLY 1069 TYR 1070 0.0322

TYR 1070 ARG 1071 0.0311

ARG 1071 LEU 1072 0.0294

LEU 1072 ALA 1073 0.0319

ALA 1073 GLU 1074 0.0291

GLU 1074 VAL 1075 0.0267

VAL 1075 ASP 1076 0.0274

ASP 1076 ILE 1077 0.0227

ILE 1077 LEU 1078 0.0315

LEU 1078 ARG 1079 0.0254

ARG 1079 ALA 1080 0.0236

ALA 1080 MET 1081 0.0244

MET 1081 LEU 1082 0.0216

LEU 1082 ILE 1083 0.0317

ILE 1083 PRO 1084 0.0312

PRO 1084 ASP 1085 0.1472

ASP 1085 THR 1086 0.0027

THR 1086 SER 1087 0.0077

SER 1087 GLU 1088 0.0180

GLU 1088 GLY 1089 0.0008

GLY 1089 LEU 1090 0.0121

LEU 1090 GLU 1091 0.0175

GLU 1091 ALA 1092 0.0060

ALA 1092 HIS 1093 0.0179

HIS 1093 ILE 1094 0.0101

ILE 1094 SER 1095 0.0181

SER 1095 LEU 1096 0.0131

LEU 1096 ARG 1097 0.0170

ARG 1097 PRO 1098 0.0137

PRO 1098 CYS 1099 0.0029

CYS 1099 SER 1100 0.0182

SER 1100 THR 1101 -0.2060

THR 1101 LYS 1102 0.0011

LYS 1102 LEU 1103 -0.0001

LEU 1103 LEU 1104 0.0009

LEU 1104 LEU 1105 0.0009

LEU 1105 THR 1106 0.0009

THR 1106 ASN 1107 0.0012

ASN 1107 GLU 1108 0.0010

GLU 1108 TRP 1109 0.0010

TRP 1109 TYR 1110 0.0012

TYR 1110 ASP 1111 0.0012

ASP 1111 PHE 1112 0.0011

PHE 1112 CYS 1113 0.0009

CYS 1113 VAL 1114 0.0010

VAL 1114 SER 1115 0.0011

SER 1115 SER 1116 0.0012

SER 1116 VAL 1117 0.0333

VAL 1117 GLY 1118 0.0071

GLY 1118 ASP 1119 0.0037

ASP 1119 ASP 1120 0.0051

ASP 1120 ASP 1121 0.0072

ASP 1121 LYS 1122 0.0048

LYS 1122 PHE 1123 0.0040

PHE 1123 VAL 1124 0.0007

VAL 1124 ASP 1125 0.0044

ASP 1125 HIS 1126 0.0013

HIS 1126 CYS 1127 0.0059

CYS 1127 ARG 1128 0.0067

ARG 1128 GLY 1129 0.0057

GLY 1129 ARG 1130 0.0071

ARG 1130 ILE 1131 0.0070

ILE 1131 THR 1132 0.0070

THR 1132 ILE 1133 0.2229

ILE 1133 GLU 1134 0.0378

GLU 1134 PHE 1135 0.0336

PHE 1135 ASP 1136 0.0454

ASP 1136 THR 1137 0.0110

THR 1137 SER 1138 0.0329

SER 1138 GLY 1139 0.0465

GLY 1139 SER 1140 0.0314

SER 1140 ALA 1141 0.0513

ALA 1141 ASP 1142 0.0031

ASP 1142 THR 1143 0.0524

THR 1143 PRO 1144 0.0357

PRO 1144 ARG 1145 0.0109

ARG 1145 THR 1146 0.0470

THR 1146 SER 1147 0.0343

SER 1147 LEU 1148 0.0061

LEU 1148 ARG 1149 -0.0076

ARG 1149 GLU 1150 0.0751

GLU 1150 ARG 1151 0.0718

ARG 1151 SER 1152 0.0470

SER 1152 ARG 1153 0.0271

ARG 1153 SER 1154 0.0730

SER 1154 THR 1155 0.0150

THR 1155 GLY 1156 0.0753

GLY 1156 LEU 1157 0.0725

LEU 1157 MET 1158 0.0322

MET 1158 ARG 1159 0.0753

ARG 1159 SER 1160 0.0629

SER 1160 VAL 1161 0.0444

VAL 1161 ASP 1162 0.0628

ASP 1162 PRO 1163 0.0006

PRO 1163 SER 1164 0.0752

SER 1164 ASN 1165 0.0492

ASN 1165 LEU 1166 0.0189

LEU 1166 TYR 1167 0.0604

TYR 1167 SER 1168 0.0359

SER 1168 PHE 1169 0.0752

PHE 1169 LEU 1170 0.0005

LEU 1170 ARG 1171 0.0750

ARG 1171 ALA 1172 0.0449

ALA 1172 GLN 1173 0.0430

GLN 1173 GLY 1174 0.0414

GLY 1174 ILE 1175 0.0615

ILE 1175 TYR 1176 0.0748

TYR 1176 HIS 1177 0.0698

HIS 1177 GLY 1178 0.0750

GLY 1178 PRO 1179 0.0721

PRO 1179 ILE 1180 0.0151

ILE 1180 PHE 1181 0.0738

PHE 1181 GLN 1182 0.0072

GLN 1182 ASN 1183 0.0777

ASN 1183 LEU 1184 0.0503

LEU 1184 LYS 1185 0.0413

LYS 1185 THR 1186 0.0630

THR 1186 ILE 1187 0.0806

ILE 1187 SER 1188 0.0688

SER 1188 SER 1189 0.0806

SER 1189 ARG 1190 0.0760

ARG 1190 LYS 1191 0.0782

LYS 1191 ASP 1192 0.0081

ASP 1192 HIS 1193 0.0768

HIS 1193 SER 1194 0.0799

SER 1194 GLU 1195 0.0789

GLU 1195 SER 1196 0.0776

SER 1196 SER 1197 0.0325

SER 1197 PHE 1198 0.0520

PHE 1198 VAL 1199 0.0566

VAL 1199 VAL 1200 0.0117

VAL 1200 ALA 1201 0.0664

ALA 1201 ASN 1202 0.0610

ASN 1202 THR 1203 0.0427

THR 1203 ALA 1204 0.0497

ALA 1204 SER 1205 0.0229

SER 1205 VAL 1206 0.0669

VAL 1206 MET 1207 0.0013

MET 1207 PRO 1208 0.0573

PRO 1208 ASN 1209 0.0673

ASN 1209 GLY 1210 0.0589

GLY 1210 PHE 1211 0.0100

PHE 1211 GLN 1212 0.0658

GLN 1212 SER 1213 0.1572

SER 1213 PRO 1214 0.0558

PRO 1214 HIS 1215 0.0523

HIS 1215 VAL 1216 0.0545

VAL 1216 ILE 1217 0.0127

ILE 1217 HIS 1218 0.0447

HIS 1218 PRO 1219 0.0514

PRO 1219 THR 1220 0.0067

THR 1220 THR 1221 0.0558

THR 1221 LEU 1222 0.0470

LEU 1222 ASP 1223 0.0370

ASP 1223 SER 1224 0.0214

SER 1224 ILE 1225 0.0517

ILE 1225 PHE 1226 0.0554

PHE 1226 GLN 1227 0.0101

GLN 1227 GLY 1228 0.0517

GLY 1228 ALA 1229 0.0125

ALA 1229 TYR 1230 0.0239

TYR 1230 THR 1231 0.0599

THR 1231 ALA 1232 0.0775

ALA 1232 LEU 1233 0.0682

LEU 1233 PRO 1234 0.0115

PRO 1234 GLY 1235 0.0498

GLY 1235 ALA 1236 0.0333

ALA 1236 GLY 1237 0.0758

GLY 1237 LEU 1238 0.0227

LEU 1238 ASP 1239 0.0796

ASP 1239 GLN 1240 0.0261

GLN 1240 ASN 1241 0.0814

ASN 1241 THR 1242 0.0201

THR 1242 ALA 1243 0.0505

ALA 1243 MET 1244 0.0384

MET 1244 ILE 1245 0.0500

ILE 1245 PRO 1246 0.0224

PRO 1246 ARG 1247 0.0410

ARG 1247 SER 1248 0.0360

SER 1248 ILE 1249 0.0590

ILE 1249 GLN 1250 0.0459

GLN 1250 GLU 1251 0.0574

GLU 1251 LEU 1252 0.0610

LEU 1252 TYR 1253 0.0555

TYR 1253 LEU 1254 0.0626

LEU 1254 SER 1255 0.0592

SER 1255 SER 1256 0.0502

SER 1256 ALA 1257 0.0360

ALA 1257 LEU 1258 0.0337

LEU 1258 THR 1259 0.0600

THR 1259 SER 1260 0.0581

SER 1260 ASP 1261 0.1482

ASP 1261 VAL 1262 0.0282

VAL 1262 GLY 1263 0.0289

GLY 1263 GLN 1264 0.0673

GLN 1264 CYS 1265 0.0623

CYS 1265 LEU 1266 0.0660

LEU 1266 VAL 1267 0.0740

VAL 1267 SER 1268 0.0802

SER 1268 ASP 1269 0.0842

ASP 1269 THR 1270 0.0851

THR 1270 SER 1271 0.0848

SER 1271 LEU 1272 0.0822

LEU 1272 ILE 1273 0.0429

ILE 1273 ARG 1274 0.0762

ARG 1274 TYR 1275 0.0430

TYR 1275 ASP 1276 0.0819

ASP 1276 GLY 1277 0.0836

GLY 1277 GLN 1278 0.0425

GLN 1278 SER 1279 0.0470

SER 1279 PHE 1280 0.0861

PHE 1280 THR 1281 0.0383

THR 1281 VAL 1282 0.0866

VAL 1282 ASN 1283 0.0587

ASN 1283 VAL 1284 0.0854

VAL 1284 ASP 1285 0.0798

ASP 1285 VAL 1286 0.0854

VAL 1286 SER 1287 0.0867

SER 1287 SER 1288 0.0841

SER 1288 LYS 1289 0.0168

LYS 1289 ALA 1290 0.0728

ALA 1290 ASP 1291 0.0530

ASP 1291 SER 1292 0.0765

SER 1292 GLU 1293 0.0841

GLU 1293 HIS 1294 0.0765

HIS 1294 THR 1295 0.0111

THR 1295 PRO 1296 0.0844

PRO 1296 VAL 1297 0.0721

VAL 1297 LEU 1298 0.0823

LEU 1298 GLU 1299 0.0840

GLU 1299 ILE 1300 0.0793

ILE 1300 LYS 1301 0.0839

LYS 1301 GLY 1302 0.0708

GLY 1302 LEU 1303 0.0702

LEU 1303 ARG 1304 0.0731

ARG 1304 ASN 1305 0.0424

ASN 1305 GLN 1306 0.0796

GLN 1306 SER 1307 0.0370

SER 1307 VAL 1308 0.0830

VAL 1308 GLY 1309 0.0173

GLY 1309 GLN 1310 0.0207

GLN 1310 MET 1311 0.0489

MET 1311 ALA 1312 0.0157

ALA 1312 PRO 1313 0.0368

PRO 1313 GLN 1314 0.0472

GLN 1314 PRO 1315 0.0176

PRO 1315 GLY 1316 0.0423

GLY 1316 ASP 1317 0.0426

ASP 1317 SER 1318 0.0243

SER 1318 SER 1319 0.0469

SER 1319 ASN 1320 0.0155

ASN 1320 ASN 1321 0.0325

ASN 1321 ASP 1322 0.0224

ASP 1322 LEU 1323 0.0482

LEU 1323 CYS 1324 0.0015

CYS 1324 PHE 1325 0.1707

PHE 1325 LYS 1326 0.0183

LYS 1326 LEU 1327 0.0250

LEU 1327 ASP 1328 0.0478

ASP 1328 TRP 1329 0.0214

TRP 1329 ALA 1330 0.0467

ALA 1330 PRO 1331 0.0356

PRO 1331 ASP 1332 0.0471

ASP 1332 ILE 1333 0.0382

ILE 1333 SER 1334 0.0402

SER 1334 SER 1335 0.0077

SER 1335 VAL 1336 0.0466

VAL 1336 LYS 1337 0.0334

LYS 1337 GLN 1338 0.0380

GLN 1338 GLU 1339 0.0303

GLU 1339 ARG 1340 0.0454

ARG 1340 LEU 1341 -0.1185

LEU 1341 LYS 1342 0.0065

LYS 1342 GLU 1343 0.0308

GLU 1343 LYS 1344 0.0042

LYS 1344 PHE 1345 0.0308

PHE 1345 GLY 1346 0.0019

GLY 1346 PHE 1347 0.0285

PHE 1347 PRO 1348 0.0092

PRO 1348 LEU 1349 0.0209

LEU 1349 ASP 1350 0.0292

ASP 1350 PRO 1351 0.0087

PRO 1351 THR 1352 0.0253

THR 1352 GLU 1353 0.0293

GLU 1353 ALA 1354 0.0046

ALA 1354 ASP 1355 0.0277

ASP 1355 ILE 1356 0.0167

ILE 1356 ILE 1357 0.0605

ILE 1357 MET 1358 0.0273

MET 1358 GLY 1359 0.1001

GLY 1359 LEU 1360 0.0651

LEU 1360 ARG 1361 0.0652

ARG 1361 GLN 1362 0.0973

GLN 1362 ALA 1363 0.0354

ALA 1363 CYS 1364 0.1155

CYS 1364 ILE 1365 0.0264

ILE 1365 HIS 1366 0.1180

HIS 1366 PHE 1367 0.0278

PHE 1367 ILE 1368 0.1054

ILE 1368 HIS 1369 0.0442

HIS 1369 ARG 1370 0.0874

ARG 1370 SER 1371 0.0695

SER 1371 LEU 1372 0.0656

LEU 1372 GLN 1373 0.1229

GLN 1373 SER 1374 0.0340

SER 1374 LEU 1375 0.1077

LEU 1375 THR 1376 0.1217

THR 1376 ALA 1377 0.1223

ALA 1377 PRO 1378 0.0118

PRO 1378 ASP 1379 0.1146

ASP 1379 ARG 1380 0.0999

ARG 1380 ASP 1381 0.1009

ASP 1381 GLN 1382 0.0266

GLN 1382 LEU 1383 0.1199

LEU 1383 ASP 1384 0.0731

ASP 1384 TRP 1385 0.1083

TRP 1385 HIS 1386 0.1228

HIS 1386 GLN 1387 0.1044

GLN 1387 LYS 1388 0.0650

LYS 1388 ARG 1389 0.2824

ARG 1389 PHE 1390 0.1127

PHE 1390 TYR 1391 0.0754

TYR 1391 ASP 1392 0.0771

ASP 1392 TRP 1393 0.1133

TRP 1393 MET 1394 0.1077

MET 1394 VAL 1395 0.0523

VAL 1395 LEU 1396 0.1028

LEU 1396 GLN 1397 0.1134

GLN 1397 ILE 1398 0.0783

ILE 1398 GLN 1399 0.0709

GLN 1399 LEU 1400 0.1134

LEU 1400 ALA 1401 0.1108

ALA 1401 GLU 1402 0.0507

GLU 1402 GLU 1403 0.0987

GLU 1403 ASP 1404 0.1134

ASP 1404 ARG 1405 0.1727

ARG 1405 LEU 1406 0.0455

LEU 1406 ALA 1407 0.1226

ALA 1407 PRO 1408 0.0241

PRO 1408 ASN 1409 0.1473

ASN 1409 SER 1410 0.0486

SER 1410 SER 1411 0.1171

SER 1411 ALA 1412 0.1526

ALA 1412 TRP 1413 0.0002

TRP 1413 LEU 1414 0.1520

LEU 1414 GLN 1415 0.1169

GLN 1415 CYS 1416 0.0965

CYS 1416 SER 1417 0.1491

SER 1417 SER 1418 0.0221

SER 1418 SER 1419 0.1519

SER 1419 ASP 1420 0.1418

ASP 1420 GLU 1421 0.1543

GLU 1421 GLN 1422 0.0478

GLN 1422 LYS 1423 0.1402

LYS 1423 LEU 1424 0.1398

LEU 1424 LEU 1425 0.0415

LEU 1425 GLU 1426 0.1102

GLU 1426 ASN 1427 0.1208

ASN 1427 VAL 1428 0.1433

VAL 1428 ARG 1429 0.0139

ARG 1429 ALA 1430 0.1425

ALA 1430 SER 1431 0.1118

SER 1431 SER 1432 0.1062

SER 1432 VAL 1433 0.0711

VAL 1433 ASN 1434 0.0722

ASN 1434 GLY 1435 0.1292

GLY 1435 GLN 1436 0.0268

GLN 1436 MET 1437 0.1042

MET 1437 VAL 1438 0.0222

VAL 1438 VAL 1439 0.1306

VAL 1439 HIS 1440 0.0191

HIS 1440 VAL 1441 0.1262

VAL 1441 GLY 1442 0.0164

GLY 1442 LYS 1443 0.1234

LYS 1443 SER 1444 0.0809

SER 1444 MET 1445 0.0880

MET 1445 LEU 1446 0.1249

LEU 1446 ALA 1447 0.0096

ALA 1447 ILE 1448 0.1254

ILE 1448 LEU 1449 0.0712

LEU 1449 ARG 1450 0.1118

ARG 1450 HIS 1451 0.0263

HIS 1451 GLU 1452 0.1190

GLU 1452 ILE 1453 0.0698

ILE 1453 ALA 1454 0.1277

ALA 1454 PRO 1455 0.0657

PRO 1455 LEU 1456 0.0933

LEU 1456 GLU 1457 0.0719

GLU 1457 LEU 1458 0.0652

LEU 1458 MET 1459 0.1162

MET 1459 LEU 1460 0.0251

LEU 1460 GLN 1461 0.1286

GLN 1461 ASP 1462 0.1304

ASP 1462 LYS 1463 0.1297

LYS 1463 LEU 1464 0.0071

LEU 1464 LEU 1465 0.1296

LEU 1465 TYR 1466 0.1097

TYR 1466 ARG 1467 0.0824

ARG 1467 TYR 1468 0.0604

TYR 1468 TYR 1469 -0.0937

TYR 1469 THR 1470 0.0138

THR 1470 ASP 1471 0.0116

ASP 1471 ALA 1472 0.0034

ALA 1472 ILE 1473 0.0048

ILE 1473 LYS 1474 0.0145

LYS 1474 TRP 1475 0.0035

TRP 1475 ASP 1476 0.0128

ASP 1476 ARG 1477 0.0061

ARG 1477 SER 1478 0.0156

SER 1478 TYR 1479 0.0003

TYR 1479 GLN 1480 0.0154

GLN 1480 GLN 1481 0.0090

GLN 1481 ILE 1482 0.0082

ILE 1482 ASP 1483 0.0077

ASP 1483 GLN 1484 0.0110

GLN 1484 LEU 1485 -0.3279

LEU 1485 VAL 1486 0.0040

VAL 1486 LYS 1487 0.0084

LYS 1487 LEU 1488 0.0106

LEU 1488 HIS 1489 0.0012

HIS 1489 ALA 1490 0.0095

ALA 1490 HIS 1491 0.0071

HIS 1491 LYS 1492 0.0101

LYS 1492 CYS 1493 0.0011

CYS 1493 PRO 1494 0.0108

PRO 1494 THR 1495 0.0005

THR 1495 ALA 1496 0.0111

ALA 1496 LYS 1497 0.0046

LYS 1497 ILE 1498 0.0087

ILE 1498 ILE 1499 0.0099

ILE 1499 GLU 1500 0.0087

GLU 1500 ILE 1501 -0.0162

ILE 1501 GLY 1502 0.0011

GLY 1502 ALA 1503 0.0001

ALA 1503 GLY 1504 0.0014

GLY 1504 THR 1505 0.0001

THR 1505 GLY 1506 0.0014

GLY 1506 GLY 1507 0.0009

GLY 1507 CYS 1508 0.0013

CYS 1508 THR 1509 0.0014

THR 1509 ARG 1510 -0.0001

ARG 1510 ALA 1511 0.0014

ALA 1511 VAL 1512 0.0007

VAL 1512 LEU 1513 0.0011

LEU 1513 ASP 1514 0.0001

ASP 1514 ALA 1515 0.0013

ALA 1515 LEU 1516 0.0011

LEU 1516 SER 1517 0.1848

SER 1517 ASN 1518 0.0025

ASN 1518 GLN 1519 0.0025

GLN 1519 GLY 1520 0.0016

GLY 1520 ILE 1521 0.0016

ILE 1521 ALA 1522 0.0027

ALA 1522 ARG 1523 0.0026

ARG 1523 CYS 1524 0.0021

CYS 1524 ALA 1525 0.0002

ALA 1525 GLN 1526 0.0023

GLN 1526 TYR 1527 0.0010

TYR 1527 ASP 1528 0.0026

ASP 1528 PHE 1529 0.0013

PHE 1529 THR 1530 0.0028

THR 1530 ASP 1531 0.0021

ASP 1531 VAL 1532 0.0024

VAL 1532 SER 1533 0.1117

SER 1533 SER 1534 0.0027

SER 1534 GLY 1535 0.0007

GLY 1535 PHE 1536 0.0027

PHE 1536 PHE 1537 0.0021

PHE 1537 GLU 1538 0.0009

GLU 1538 ALA 1539 0.0027

ALA 1539 ALA 1540 0.0004

ALA 1540 GLN 1541 0.0030

GLN 1541 GLN 1542 0.0010

GLN 1542 LYS 1543 0.0028

LYS 1543 PHE 1544 0.0005

PHE 1544 ALA 1545 0.0027

ALA 1545 ALA 1546 0.0022

ALA 1546 PHE 1547 0.0009

PHE 1547 ASP 1548 0.0029

ASP 1548 ASP 1549 0.0838

ASP 1549 VAL 1550 0.0028

VAL 1550 ILE 1551 0.0019

ILE 1551 ARG 1552 -0.0001

ARG 1552 PHE 1553 0.0018

PHE 1553 GLN 1554 0.0009

GLN 1554 LYS 1555 0.0019

LYS 1555 LEU 1556 0.0029

LEU 1556 ASP 1557 0.0020

ASP 1557 ILE 1558 0.0024

ILE 1558 GLU 1559 0.0011

GLU 1559 LYS 1560 0.0023

LYS 1560 ASP 1561 0.0028

ASP 1561 ILE 1562 0.0012

ILE 1562 GLU 1563 0.0026

GLU 1563 MET 1564 0.0011

MET 1564 GLN 1565 0.0382

GLN 1565 GLY 1566 0.0042

GLY 1566 PHE 1567 0.0004

PHE 1567 GLU 1568 0.0026

GLU 1568 CYS 1569 0.0007

CYS 1569 GLY 1570 0.0014

GLY 1570 SER 1571 0.0030

SER 1571 TYR 1572 0.0037

TYR 1572 ASP 1573 0.0011

ASP 1573 LEU 1574 0.0040

LEU 1574 VAL 1575 0.0036

VAL 1575 ILE 1576 0.0040

ILE 1576 ALA 1577 0.0041

ALA 1577 SER 1578 0.0040

SER 1578 GLN 1579 0.0042

GLN 1579 VAL 1580 0.0030

VAL 1580 LEU 1581 -0.1874

LEU 1581 HIS 1582 0.0132

HIS 1582 ALA 1583 0.0047

ALA 1583 THR 1584 0.0121

THR 1584 GLY 1585 0.0149

GLY 1585 LYS 1586 0.0144

LYS 1586 MET 1587 0.0083

MET 1587 GLU 1588 0.0159

GLU 1588 HIS 1589 0.0015

HIS 1589 THR 1590 0.0155

THR 1590 MET 1591 0.0093

MET 1591 ALA 1592 0.0096

ALA 1592 ASN 1593 0.0104

ASN 1593 VAL 1594 0.0071

VAL 1594 ARG 1595 0.0156

ARG 1595 LYS 1596 0.0017

LYS 1596 LEU 1597 0.1486

LEU 1597 LEU 1598 0.0028

LEU 1598 LYS 1599 0.0073

LYS 1599 PRO 1600 0.0023

PRO 1600 GLY 1601 0.0038

GLY 1601 GLY 1602 0.0050

GLY 1602 LYS 1603 0.0062

LYS 1603 LEU 1604 0.0075

LEU 1604 LEU 1605 0.0071

LEU 1605 LEU 1606 0.0075

LEU 1606 VAL 1607 0.0073

VAL 1607 GLU 1608 0.0075

GLU 1608 THR 1609 0.0061

THR 1609 THR 1610 0.0022

THR 1610 ARG 1611 0.0063

ARG 1611 ASP 1612 0.0050

ASP 1612 GLU 1613 0.3035

GLU 1613 MET 1614 0.0780

MET 1614 ASP 1615 0.0340

ASP 1615 LEU 1616 0.0477

LEU 1616 GLN 1617 0.0704

GLN 1617 LEU 1618 0.0793

LEU 1618 VAL 1619 0.0103

VAL 1619 PHE 1620 0.0663

PHE 1620 GLY 1621 0.0514

GLY 1621 LEU 1622 0.0576

LEU 1622 LEU 1623 0.0335

LEU 1623 PRO 1624 0.0785

PRO 1624 GLY 1625 0.0753

GLY 1625 TRP 1626 0.0121

TRP 1626 TRP 1627 0.0674

TRP 1627 LEU 1628 0.0496

LEU 1628 SER 1629 0.1540

SER 1629 SER 1630 0.0610

SER 1630 GLU 1631 0.0285

GLU 1631 GLU 1632 0.0114

GLU 1632 GLU 1633 0.0561

GLU 1633 ARG 1634 0.0271

ARG 1634 GLN 1635 0.0636

GLN 1635 MET 1636 0.0465

MET 1636 SER 1637 0.0513

SER 1637 PRO 1638 0.0181

PRO 1638 SER 1639 0.0499

SER 1639 LEU 1640 0.0524

LEU 1640 SER 1641 0.0230

SER 1641 THR 1642 0.0627

THR 1642 ASN 1643 0.0461

ASN 1643 SER 1644 0.0385

SER 1644 TRP 1645 0.3064

TRP 1645 GLU 1646 0.0170

GLU 1646 LYS 1647 0.0175

LYS 1647 VAL 1648 0.0036

VAL 1648 LEU 1649 0.0187

LEU 1649 LYS 1650 0.0181

LYS 1650 LYS 1651 0.0126

LYS 1651 THR 1652 0.0081

THR 1652 GLY 1653 0.0192

GLY 1653 PHE 1654 0.0105

PHE 1654 ASP 1655 0.0070

ASP 1655 GLY 1656 0.0126

GLY 1656 LEU 1657 0.0157

LEU 1657 ASP 1658 0.0191

ASP 1658 ILE 1659 0.0158

ILE 1659 GLU 1660 0.0163

GLU 1660 LEU 1661 0.0512

LEU 1661 ARG 1662 0.0139

ARG 1662 ASP 1663 0.0158

ASP 1663 CYS 1664 0.0051

CYS 1664 ASP 1665 0.0067

ASP 1665 SER 1666 0.0103

SER 1666 ASP 1667 0.0145

ASP 1667 GLU 1668 0.0177

GLU 1668 PHE 1669 0.0033

PHE 1669 TYR 1670 0.0099

TYR 1670 SER 1671 0.0121

SER 1671 PHE 1672 0.0061

PHE 1672 SER 1673 0.0179

SER 1673 VAL 1674 0.0053

VAL 1674 MET 1675 0.0179

MET 1675 MET 1676 0.0125

MET 1676 ALA 1677 0.2061

ALA 1677 THR 1678 0.0532

THR 1678 ALA 1679 0.0523

ALA 1679 SER 1680 0.0682

SER 1680 SER 1681 0.0542

SER 1681 THR 1682 0.0773

THR 1682 ILE 1683 0.0758

ILE 1683 ALA 1684 0.0534

ALA 1684 SER 1685 0.0551

SER 1685 SER 1686 0.0543

SER 1686 SER 1687 0.0757

SER 1687 MET 1688 0.0762

MET 1688 ALA 1689 0.0644

ALA 1689 PHE 1690 0.0611

PHE 1690 ALA 1691 0.0726

ALA 1691 ILE 1692 0.0506

ILE 1692 VAL 1693 0.2490

VAL 1693 TYR 1694 0.0187

TYR 1694 GLY 1695 0.0246

GLY 1695 GLU 1696 0.0235

GLU 1696 VAL 1697 0.0023

VAL 1697 PRO 1698 0.0241

PRO 1698 LEU 1699 0.0216

LEU 1699 PRO 1700 0.0020

PRO 1700 ASP 1701 0.0264

ASP 1701 GLN 1702 0.0174

GLN 1702 PHE 1703 0.0152

PHE 1703 LEU 1704 0.0126

LEU 1704 ASP 1705 0.0204

ASP 1705 ASP 1706 0.0248

ASP 1706 MET 1707 0.0024

MET 1707 LYS 1708 0.0241

LYS 1708 THR 1709 0.0387

THR 1709 ALA 1710 0.0275

ALA 1710 ILE 1711 0.0025

ILE 1711 SER 1712 0.0294

SER 1712 SER 1713 0.0229

SER 1713 SER 1714 0.0106

SER 1714 ALA 1715 0.0159

ALA 1715 VAL 1716 0.0300

VAL 1716 SER 1717 0.0304

SER 1717 ASP 1718 0.0203

ASP 1718 PRO 1719 0.0252

PRO 1719 VAL 1720 0.0280

VAL 1720 VAL 1721 0.0260

VAL 1721 GLY 1722 0.0230

GLY 1722 HIS 1723 0.0289

HIS 1723 LEU 1724 0.0081

LEU 1724 ASP 1725 0.0904

ASP 1725 SER 1726 0.0164

SER 1726 ILE 1727 0.0191

ILE 1727 ASP 1728 0.0124

ASP 1728 ALA 1729 0.0189

ALA 1729 THR 1730 0.0118

THR 1730 GLY 1731 0.0186

GLY 1731 LYS 1732 0.0047

LYS 1732 PHE 1733 0.0178

PHE 1733 CYS 1734 0.0180

CYS 1734 ILE 1735 0.0111

ILE 1735 PHE 1736 0.0178

PHE 1736 ILE 1737 0.0090

ILE 1737 GLU 1738 0.0174

GLU 1738 ASP 1739 0.0121

ASP 1739 PRO 1740 0.0191

PRO 1740 GLU 1741 0.0891

GLU 1741 THR 1742 0.0033

THR 1742 ASP 1743 0.0066

ASP 1743 ILE 1744 0.0095

ILE 1744 LEU 1745 0.0068

LEU 1745 SER 1746 0.0146

SER 1746 SER 1747 0.0127

SER 1747 PRO 1748 0.0142

PRO 1748 ASP 1749 0.0133

ASP 1749 GLU 1750 0.0079

GLU 1750 LYS 1751 0.0075

LYS 1751 SER 1752 0.0087

SER 1752 TYR 1753 0.0063

TYR 1753 ALA 1754 0.0127

ALA 1754 SER 1755 0.0021

SER 1755 ILE 1756 0.0144

ILE 1756 GLN 1757 0.0100

GLN 1757 LYS 1758 0.0159

LYS 1758 LEU 1759 0.0075

LEU 1759 VAL 1760 0.0124

VAL 1760 THR 1761 0.0077

THR 1761 ARG 1762 0.0119

ARG 1762 CYS 1763 0.0083

CYS 1763 LYS 1764 0.0173

LYS 1764 GLY 1765 0.0151

GLY 1765 LEU 1766 0.0131

LEU 1766 ILE 1767 0.0082

ILE 1767 TRP 1768 0.0174

TRP 1768 VAL 1769 0.0040

VAL 1769 SER 1770 0.0175

SER 1770 ARG 1771 0.0116

ARG 1771 GLY 1772 0.0167

GLY 1772 GLY 1773 -0.0258

GLY 1773 ALA 1774 0.0120

ALA 1774 MET 1775 0.0108

MET 1775 HIS 1776 0.0107

HIS 1776 GLY 1777 0.0100

GLY 1777 THR 1778 0.0035

THR 1778 ARG 1779 0.0103

ARG 1779 PRO 1780 0.0006

PRO 1780 ASN 1781 0.0120

ASN 1781 SER 1782 0.0111

SER 1782 SER 1783 0.0056

SER 1783 LEU 1784 0.0067

LEU 1784 LYS 1785 0.0123

LYS 1785 THR 1786 0.0126

THR 1786 GLY 1787 0.0028

GLY 1787 LEU 1788 0.0120

LEU 1788 LEU 1789 0.0505

LEU 1789 ARG 1790 0.0118

ARG 1790 THR 1791 0.0095

THR 1791 LEU 1792 0.0176

LEU 1792 ARG 1793 0.0187

ARG 1793 LEU 1794 0.0018

LEU 1794 GLU 1795 0.0187

GLU 1795 TYR 1796 0.0158

TYR 1796 THR 1797 0.0183

THR 1797 GLU 1798 0.0171

GLU 1798 LYS 1799 0.0033

LYS 1799 ARG 1800 0.0085

ARG 1800 PHE 1801 0.0163

PHE 1801 ILE 1802 0.0071

ILE 1802 SER 1803 0.0136

SER 1803 LEU 1804 0.0021

LEU 1804 ASP 1805 0.0065

ASP 1805 LEU 1806 0.0004

LEU 1806 ASP 1807 0.0284

ASP 1807 SER 1808 0.0380

SER 1808 ALA 1809 0.0130

ALA 1809 ARG 1810 0.0259

ARG 1810 PRO 1811 0.0324

PRO 1811 GLN 1812 0.0228

GLN 1812 TRP 1813 0.0313

TRP 1813 ASN 1814 0.0263

ASN 1814 HIS 1815 0.0366

HIS 1815 ASP 1816 0.0279

ASP 1816 SER 1817 0.0122

SER 1817 ILE 1818 0.0375

ILE 1818 THR 1819 0.0377

THR 1819 THR 1820 0.0111

THR 1820 ILE 1821 -0.0333

ILE 1821 ASN 1822 0.0207

ASN 1822 GLU 1823 0.0236

GLU 1823 VAL 1824 0.0021

VAL 1824 LEU 1825 0.0227

LEU 1825 CYS 1826 0.0190

CYS 1826 GLY 1827 0.0176

GLY 1827 ALA 1828 0.0070

ALA 1828 LEU 1829 0.0225

LEU 1829 ALA 1830 0.0199

ALA 1830 GLN 1831 0.0081

GLN 1831 ASN 1832 0.0204

ASN 1832 ALA 1833 0.0021

ALA 1833 ASP 1834 0.0234

ASP 1834 SER 1835 0.0211

SER 1835 SER 1836 0.0056

SER 1836 ILE 1837 0.0402

ILE 1837 LYS 1838 0.0242

LYS 1838 ASP 1839 0.0294

ASP 1839 SER 1840 0.0476

SER 1840 GLU 1841 0.0364

GLU 1841 PHE 1842 0.0068

PHE 1842 ALA 1843 0.0256

ALA 1843 GLU 1844 0.0038

GLU 1844 GLN 1845 0.0408

GLN 1845 ASP 1846 0.0083

ASP 1846 GLY 1847 0.0483

GLY 1847 GLN 1848 0.0138

GLN 1848 LEU 1849 0.0128

LEU 1849 PHE 1850 0.0189

PHE 1850 VAL 1851 0.0020

VAL 1851 PRO 1852 0.0227

PRO 1852 ARG 1853 -0.0946

ARG 1853 ILE 1854 0.0504

ILE 1854 SER 1855 0.0163

SER 1855 CYS 1856 0.0458

CYS 1856 ASP 1857 0.0379

ASP 1857 ILE 1858 0.0237

ILE 1858 ALA 1859 0.0350

ALA 1859 ARG 1860 0.0232

ARG 1860 ASN 1861 0.0469

ASN 1861 GLU 1862 0.0057

GLU 1862 ASP 1863 0.0502

ASP 1863 LEU 1864 0.0120

LEU 1864 SER 1865 0.0465

SER 1865 SER 1866 0.0090

SER 1866 ASP 1867 0.0467

ASP 1867 SER 1868 0.0503

SER 1868 ASN 1869 -0.0561

ASN 1869 SER 1870 0.0056

SER 1870 PRO 1871 0.0303

PRO 1871 ALA 1872 0.0184

ALA 1872 GLN 1873 0.0136

GLN 1873 MET 1874 0.0253

MET 1874 GLU 1875 0.0055

GLU 1875 PRO 1876 0.0166

PRO 1876 PHE 1877 0.0295

PHE 1877 HIS 1878 0.0010

HIS 1878 GLN 1879 0.0264

GLN 1879 PRO 1880 0.0069

PRO 1880 GLY 1881 0.0298

GLY 1881 LYS 1882 0.0004

LYS 1882 LEU 1883 0.0183

LEU 1883 LEU 1884 0.0085

LEU 1884 GLN 1885 -0.1887

GLN 1885 MET 1886 0.0751

MET 1886 GLY 1887 0.0728

GLY 1887 ILE 1888 0.0862

ILE 1888 LYS 1889 0.0916

LYS 1889 THR 1890 0.0319

THR 1890 PRO 1891 0.0276

PRO 1891 GLY 1892 0.0876

GLY 1892 LEU 1893 0.0254

LEU 1893 ILE 1894 0.0962

ILE 1894 ASP 1895 0.0258

ASP 1895 THR 1896 0.0982

THR 1896 LEU 1897 0.1023

LEU 1897 GLN 1898 0.0286

GLN 1898 PHE 1899 0.0812

PHE 1899 SER 1900 0.0936

SER 1900 LYS 1901 -0.0276

LYS 1901 THR 1902 0.1095

THR 1902 ASP 1903 0.1090

ASP 1903 ALA 1904 0.1291

ALA 1904 THR 1905 0.1200

THR 1905 ASP 1906 0.0987

ASP 1906 ASN 1907 0.0635

ASN 1907 LEU 1908 0.0793

LEU 1908 PRO 1909 0.0445

PRO 1909 ASN 1910 0.1259

ASN 1910 ASP 1911 0.0543

ASP 1911 TYR 1912 0.1095

TYR 1912 ILE 1913 0.1000

ILE 1913 GLU 1914 0.0762

GLU 1914 ILE 1915 0.1295

ILE 1915 GLU 1916 0.0821

GLU 1916 PRO 1917 -0.0303

PRO 1917 LYS 1918 0.1290

LYS 1918 ALA 1919 0.0350

ALA 1919 PHE 1920 0.0381

PHE 1920 GLY 1921 0.0212

GLY 1921 LEU 1922 0.1160

LEU 1922 ASN 1923 0.0103

ASN 1923 PHE 1924 0.0611

PHE 1924 ARG 1925 0.1399

ARG 1925 ASP 1926 0.0288

ASP 1926 VAL 1927 0.1279

VAL 1927 MET 1928 0.0448

MET 1928 VAL 1929 0.1018

VAL 1929 ALA 1930 0.0896

ALA 1930 MET 1931 0.0535

MET 1931 GLY 1932 0.1223

GLY 1932 GLN 1933 0.1897

GLN 1933 LEU 1934 0.1345

LEU 1934 GLU 1935 0.1351

GLU 1935 GLU 1936 0.0606

GLU 1936 SER 1937 0.0302

SER 1937 ILE 1938 0.1164

ILE 1938 MET 1939 0.1177

MET 1939 GLY 1940 0.1100

GLY 1940 PHE 1941 0.1032

PHE 1941 GLU 1942 0.1045

GLU 1942 CYS 1943 0.0235

CYS 1943 ALA 1944 0.0960

ALA 1944 GLY 1945 0.0215

GLY 1945 VAL 1946 0.0774

VAL 1946 VAL 1947 0.1351

VAL 1947 ARG 1948 0.0626

ARG 1948 ARG 1949 0.0894

ARG 1949 VAL 1950 0.0763

VAL 1950 GLY 1951 0.1303

GLY 1951 PRO 1952 0.1507

PRO 1952 SER 1953 0.0111

SER 1953 SER 1954 0.1509

SER 1954 ALA 1955 0.0834

ALA 1955 GLY 1956 0.0852

GLY 1956 HIS 1957 0.1118

HIS 1957 ASN 1958 0.1025

ASN 1958 ILE 1959 0.1267

ILE 1959 LYS 1960 0.0001

LYS 1960 VAL 1961 0.0790

VAL 1961 GLY 1962 0.1456

GLY 1962 ASP 1963 0.0246

ASP 1963 ARG 1964 0.1343

ARG 1964 VAL 1965 0.1588

VAL 1965 CYS 1966 0.0637

CYS 1966 ALA 1967 0.0998

ALA 1967 LEU 1968 0.0523

LEU 1968 LEU 1969 0.1137

LEU 1969 GLY 1970 0.1103

GLY 1970 GLY 1971 0.1205

GLY 1971 GLN 1972 0.0103

GLN 1972 TRP 1973 0.0856

TRP 1973 THR 1974 0.0394

THR 1974 ASN 1975 0.0317

ASN 1975 THR 1976 0.1225

THR 1976 VAL 1977 0.0180

VAL 1977 ARG 1978 0.1115

ARG 1978 VAL 1979 0.0340

VAL 1979 HIS 1980 0.0932

HIS 1980 TRP 1981 0.1262

TRP 1981 HIS 1982 0.0117

HIS 1982 SER 1983 0.1299

SER 1983 VAL 1984 0.0606

VAL 1984 ALA 1985 0.1313

ALA 1985 PRO 1986 0.0609

PRO 1986 ILE 1987 0.1307

ILE 1987 PRO 1988 0.1252

PRO 1988 GLN 1989 0.0076

GLN 1989 ALA 1990 0.1269

ALA 1990 MET 1991 0.0948

MET 1991 ASP 1992 0.1102

ASP 1992 TRP 1993 0.1308

TRP 1993 GLU 1994 0.0902

GLU 1994 THR 1995 0.0726

THR 1995 ALA 1996 0.1306

ALA 1996 ALA 1997 0.2123

ALA 1997 SER 1998 0.0590

SER 1998 ILE 1999 0.0856

ILE 1999 PRO 2000 0.1163

PRO 2000 ILE 2001 0.0770

ILE 2001 VAL 2002 0.1021

VAL 2002 PHE 2003 0.1176

PHE 2003 VAL 2004 0.1154

VAL 2004 THR 2005 0.0770

THR 2005 ALA 2006 0.1046

ALA 2006 TYR 2007 0.1216

TYR 2007 ILE 2008 0.1025

ILE 2008 SER 2009 0.0747

SER 2009 LEU 2010 0.1134

LEU 2010 VAL 2011 0.1176

VAL 2011 LYS 2012 0.1203

LYS 2012 ILE 2013 0.3291

ILE 2013 ALA 2014 0.0617

ALA 2014 ARG 2015 0.0847

ARG 2015 MET 2016 0.0961

MET 2016 GLN 2017 0.1058

GLN 2017 ALA 2018 0.1059

ALA 2018 GLY 2019 0.0222

GLY 2019 GLU 2020 0.0962

GLU 2020 THR 2021 0.0933

THR 2021 VAL 2022 0.0903

VAL 2022 LEU 2023 0.0986

LEU 2023 ILE 2024 0.0484

ILE 2024 HIS 2025 0.1031

HIS 2025 ALA 2026 0.0729

ALA 2026 ALA 2027 0.0934

ALA 2027 SER 2028 0.0755

SER 2028 GLY 2029 -0.1489

GLY 2029 GLY 2030 0.0909

GLY 2030 VAL 2031 0.0761

VAL 2031 GLY 2032 0.0767

GLY 2032 GLN 2033 0.0874

GLN 2033 ALA 2034 0.1254

ALA 2034 ALA 2035 0.0084

ALA 2035 ILE 2036 0.1310

ILE 2036 ILE 2037 0.0612

ILE 2037 LEU 2038 0.1218

LEU 2038 ALA 2039 0.0168

ALA 2039 LYS 2040 0.1246

LYS 2040 HIS 2041 0.1001

HIS 2041 VAL 2042 0.0490

VAL 2042 GLY 2043 0.1000

GLY 2043 ALA 2044 0.0907

ALA 2044 GLU 2045 0.0454

GLU 2045 ILE 2046 0.1494

ILE 2046 PHE 2047 0.1290

PHE 2047 ALA 2048 0.1181

ALA 2048 THR 2049 0.1608

THR 2049 VAL 2050 0.1088

VAL 2050 GLY 2051 0.1614

GLY 2051 THR 2052 0.1551

THR 2052 ASP 2053 0.1610

ASP 2053 GLU 2054 0.0044

GLU 2054 LYS 2055 0.1613

LYS 2055 ARG 2056 0.0728

ARG 2056 ASP 2057 0.1199

ASP 2057 LEU 2058 0.0808

LEU 2058 LEU 2059 0.1093

LEU 2059 ILE 2060 0.1427

ILE 2060 LYS 2061 0.1074

LYS 2061 GLU 2062 0.1061

GLU 2062 TYR 2063 0.1171

TYR 2063 LYS 2064 0.0977

LYS 2064 ILE 2065 0.0757

ILE 2065 PRO 2066 0.0576

PRO 2066 ASP 2067 0.1496

ASP 2067 ASP 2068 0.0397

ASP 2068 HIS 2069 0.1320

HIS 2069 ILE 2070 0.1426

ILE 2070 PHE 2071 0.1251

PHE 2071 SER 2072 0.1630

SER 2072 SER 2073 0.1464

SER 2073 ARG 2074 0.1439

ARG 2074 ASN 2075 0.0130

ASN 2075 ALA 2076 0.1176

ALA 2076 LEU 2077 0.2994

LEU 2077 PHE 2078 0.0481

PHE 2078 ALA 2079 0.1041

ALA 2079 LYS 2080 0.0334

LYS 2080 SER 2081 0.0939

SER 2081 ILE 2082 0.0677

ILE 2082 ARG 2083 0.0580

ARG 2083 GLN 2084 0.0906

GLN 2084 ARG 2085 0.0370

ARG 2085 THR 2086 0.1117

THR 2086 ASN 2087 0.0175

ASN 2087 GLY 2088 0.1114

GLY 2088 LYS 2089 0.0492

LYS 2089 GLY 2090 0.0826

GLY 2090 VAL 2091 0.0003

VAL 2091 ASP 2092 0.0824

ASP 2092 VAL 2093 0.1112

VAL 2093 VAL 2094 0.0899

VAL 2094 LEU 2095 0.0408

LEU 2095 ASN 2096 0.0763

ASN 2096 CYS 2097 0.0837

CYS 2097 LEU 2098 0.0195

LEU 2098 ALA 2099 0.0794

ALA 2099 GLY 2100 0.0155

GLY 2100 GLY 2101 0.0346

GLY 2101 LEU 2102 0.0660

LEU 2102 LEU 2103 0.0658

LEU 2103 GLN 2104 0.0280

GLN 2104 GLU 2105 0.0829

GLU 2105 SER 2106 0.0201

SER 2106 PHE 2107 0.0903

PHE 2107 ASP 2108 0.0142

ASP 2108 CYS 2109 -0.0791

CYS 2109 LEU 2110 0.0451

LEU 2110 ALA 2111 0.0558

ALA 2111 ASP 2112 0.0559

ASP 2112 PHE 2113 0.0197

PHE 2113 GLY 2114 0.0487

GLY 2114 ARG 2115 0.0218

ARG 2115 PHE 2116 0.0593

PHE 2116 ILE 2117 0.0109

ILE 2117 GLU 2118 0.0593

GLU 2118 ILE 2119 0.0165

ILE 2119 GLY 2120 0.0502

GLY 2120 LYS 2121 0.0578

LYS 2121 ARG 2122 0.0342

ARG 2122 ASP 2123 0.0183

ASP 2123 ILE 2124 0.0445

ILE 2124 GLU 2125 0.0303

GLU 2125 LEU 2126 0.0023

LEU 2126 ASN 2127 0.0369

ASN 2127 HIS 2128 0.0283

HIS 2128 CYS 2129 0.0367

CYS 2129 LEU 2130 0.0262

LEU 2130 ASN 2131 0.0337

ASN 2131 MET 2132 0.0280

MET 2132 GLY 2133 0.0363

GLY 2133 MET 2134 0.0127

MET 2134 PHE 2135 0.0244

PHE 2135 ALA 2136 0.0341

ALA 2136 ARG 2137 0.0260

ARG 2137 SER 2138 0.0147

SER 2138 ALA 2139 0.0374

ALA 2139 THR 2140 0.0281

THR 2140 PHE 2141 0.0491

PHE 2141 THR 2142 0.0125

THR 2142 ALA 2143 0.0603

ALA 2143 VAL 2144 0.0236

VAL 2144 ASP 2145 0.0446

ASP 2145 LEU 2146 0.0338

LEU 2146 ILE 2147 0.0946

ILE 2147 ALA 2148 0.0750

ALA 2148 ILE 2149 0.1207

ILE 2149 GLY 2150 0.0001

GLY 2150 ARG 2151 0.1207

ARG 2151 ASP 2152 0.0641

ASP 2152 ARG 2153 0.1192

ARG 2153 SER 2154 0.0304

SER 2154 TYR 2155 0.1179

TYR 2155 MET 2156 0.0790

MET 2156 PHE 2157 0.3430

PHE 2157 ALA 2158 0.1049

ALA 2158 GLU 2159 0.0747

GLU 2159 ALA 2160 0.1354

ALA 2160 LEU 2161 0.0311

LEU 2161 PRO 2162 0.1122

PRO 2162 LYS 2163 0.0595

LYS 2163 ILE 2164 0.1397

ILE 2164 MET 2165 0.0075

MET 2165 THR 2166 0.1364

THR 2166 LEU 2167 0.0751

LEU 2167 LEU 2168 0.0900

LEU 2168 GLN 2169 0.0685

GLN 2169 GLU 2170 0.0927

GLU 2170 LYS 2171 0.1309

LYS 2171 ALA 2172 0.0167

ALA 2172 ILE 2173 0.0656

ILE 2173 ARG 2174 0.0699

ARG 2174 PRO 2175 0.1111

PRO 2175 VAL 2176 0.1172

VAL 2176 THR 2177 0.1049

THR 2177 PRO 2178 0.0821

PRO 2178 ILE 2179 0.0968

ILE 2179 SER 2180 0.1084

SER 2180 ILE 2181 0.0411

ILE 2181 TYR 2182 0.1116

TYR 2182 LYS 2183 0.0580

LYS 2183 ILE 2184 0.1223

ILE 2184 GLY 2185 0.0908

GLY 2185 ASP 2186 0.0814

ASP 2186 ILE 2187 0.0451

ILE 2187 GLU 2188 0.1150

GLU 2188 THR 2189 0.1076

THR 2189 ALA 2190 0.1045

ALA 2190 PHE 2191 0.0755

PHE 2191 ARG 2192 0.1270

ARG 2192 LEU 2193 0.1291

LEU 2193 MET 2194 0.0756

MET 2194 GLN 2195 0.1040

GLN 2195 ALA 2196 0.1296

ALA 2196 GLY 2197 0.1086

GLY 2197 LYS 2198 0.0883

LYS 2198 HIS 2199 0.1105

HIS 2199 MET 2200 0.1232

MET 2200 GLY 2201 0.1284

GLY 2201 LYS 2202 0.0972

LYS 2202 ILE 2203 0.0721

ILE 2203 VAL 2204 0.0643

VAL 2204 ILE 2205 -0.0329

ILE 2205 THR 2206 0.0027

THR 2206 ALA 2207 0.0452

ALA 2207 PRO 2208 0.0048

PRO 2208 GLU 2209 0.0364

GLU 2209 ASP 2210 0.0504

ASP 2210 ALA 2211 0.0006

ALA 2211 MET 2212 0.0400

MET 2212 VAL 2213 0.0043

VAL 2213 PRO 2214 0.0297

PRO 2214 VAL 2215 0.0508

VAL 2215 ILE 2216 0.0321

ILE 2216 THR 2217 0.0446

THR 2217 ARG 2218 0.0232

ARG 2218 PRO 2219 0.0501

PRO 2219 PRO 2220 0.0490

PRO 2220 LYS 2221 0.8850

LYS 2221 LEU 2222 0.0059

LEU 2222 GLN 2223 0.0389

GLN 2223 LEU 2224 0.0086

LEU 2224 ARG 2225 0.0359

ARG 2225 PRO 2226 0.0387

PRO 2226 ASP 2227 0.0177

ASP 2227 ALA 2228 0.0227

ALA 2228 SER 2229 0.0282

SER 2229 TYR 2230 0.0392

TYR 2230 LEU 2231 0.0139

LEU 2231 ILE 2232 0.0386

ILE 2232 VAL 2233 0.0133

VAL 2233 GLY 2234 0.0372

GLY 2234 GLY 2235 0.0152

GLY 2235 LEU 2236 0.0391

LEU 2236 GLY 2237 0.0189

GLY 2237 GLY 2238 0.0029

GLY 2238 ILE 2239 0.0328

ILE 2239 GLY 2240 0.0213

GLY 2240 ARG 2241 0.0191

ARG 2241 SER 2242 0.0159

SER 2242 LEU 2243 0.0233

LEU 2243 CYS 2244 0.0318

CYS 2244 LYS 2245 0.0020

LYS 2245 ASN 2246 0.0312

ASN 2246 PHE 2247 0.0156

PHE 2247 VAL 2248 0.0304

VAL 2248 GLU 2249 0.0033

GLU 2249 ASN 2250 0.0299

ASN 2250 GLY 2251 0.0256

GLY 2251 ALA 2252 0.0070

ALA 2252 ARG 2253 0.1077

ARG 2253 SER 2254 0.0039

SER 2254 LEU 2255 0.0331

LEU 2255 VAL 2256 0.0060

VAL 2256 LEU 2257 0.0358

LEU 2257 LEU 2258 0.0108

LEU 2258 SER 2259 0.0346

SER 2259 ARG 2260 0.0122

ARG 2260 ASN 2261 0.0324

ASN 2261 ALA 2262 0.0294

ALA 2262 ASN 2263 0.0339

ASN 2263 VAL 2264 0.0150

VAL 2264 SER 2265 0.0269

SER 2265 GLN 2266 0.0303

GLN 2266 GLN 2267 0.0260

GLN 2267 SER 2268 0.0340

SER 2268 GLY 2269 0.0430

GLY 2269 GLU 2270 0.0007

GLU 2270 PHE 2271 0.0361

PHE 2271 LEU 2272 0.0161

LEU 2272 ASP 2273 0.0310

ASP 2273 GLU 2274 0.0081

GLU 2274 LEU 2275 0.0301

LEU 2275 ARG 2276 0.0273

ARG 2276 SER 2277 0.0116

SER 2277 THR 2278 0.0319

THR 2278 GLY 2279 0.0150

GLY 2279 CYS 2280 0.0286

CYS 2280 ILE 2281 0.0002

ILE 2281 VAL 2282 0.0345

VAL 2282 GLY 2283 0.0034

GLY 2283 VAL 2284 0.0353

VAL 2284 VAL 2285 -0.1491

VAL 2285 ASP 2286 0.0277

ASP 2286 CYS 2287 0.0302

CYS 2287 ASP 2288 0.0324

ASP 2288 ILE 2289 0.0320

ILE 2289 SER 2290 0.0262

SER 2290 SER 2291 0.0090

SER 2291 LYS 2292 0.0284

LYS 2292 THR 2293 0.0225

THR 2293 GLN 2294 0.0128

GLN 2294 VAL 2295 0.0233

VAL 2295 GLU 2296 0.0147

GLU 2296 ALA 2297 0.0318

ALA 2297 THR 2298 0.0010

THR 2298 MET 2299 0.0325

MET 2299 LEU 2300 0.0140

LEU 2300 ARG 2301 0.0776

ARG 2301 LEU 2302 0.0069

LEU 2302 LYS 2303 0.0263

LYS 2303 LYS 2304 0.0273

LYS 2304 ASP 2305 0.0138

ASP 2305 MET 2306 0.0141

MET 2306 LEU 2307 0.0205

LEU 2307 PRO 2308 0.0220

PRO 2308 ILE 2309 0.0272

ILE 2309 ARG 2310 0.0183

ARG 2310 GLY 2311 0.0269

GLY 2311 ILE 2312 0.0219

ILE 2312 VAL 2313 0.0247

VAL 2313 HIS 2314 0.0126

HIS 2314 ALA 2315 0.0230

ALA 2315 GLY 2316 0.0077

GLY 2316 MET 2317 -0.2899

MET 2317 VAL 2318 0.0028

VAL 2318 LEU 2319 0.0049

LEU 2319 GLN 2320 0.0051

GLN 2320 ASP 2321 0.0060

ASP 2321 SER 2322 0.0063

SER 2322 VAL 2323 0.0059

VAL 2323 PHE 2324 0.0023

PHE 2324 GLU 2325 0.0047

GLU 2325 ARG 2326 0.0033

ARG 2326 MET 2327 0.0041

MET 2327 SER 2328 0.0062

SER 2328 LEU 2329 0.0017

LEU 2329 ASP 2330 0.0051

ASP 2330 ASP 2331 0.0060

ASP 2331 TYR 2332 0.0008

TYR 2332 ASN 2333 -0.2269

ASN 2333 THR 2334 0.0014

THR 2334 ALA 2335 0.0020

ALA 2335 ILE 2336 0.0030

ILE 2336 ARG 2337 0.0028

ARG 2337 PRO 2338 0.0000

PRO 2338 LYS 2339 0.0028

LYS 2339 VAL 2340 0.0014

VAL 2340 GLN 2341 0.0028

GLN 2341 GLY 2342 0.0004

GLY 2342 SER 2343 0.0023

SER 2343 TRP 2344 0.0019

TRP 2344 ASN 2345 0.0028

ASN 2345 LEU 2346 0.0002

LEU 2346 HIS 2347 0.0028

HIS 2347 SER 2348 0.0023

SER 2348 GLY 2349 0.1404

GLY 2349 LEU 2350 0.0061

LEU 2350 SER 2351 0.0145

SER 2351 ASP 2352 0.0168

ASP 2352 CYS 2353 0.0017

CYS 2353 ASP 2354 0.0074

ASP 2354 LEU 2355 0.0097

LEU 2355 ASP 2356 0.0007

ASP 2356 PHE 2357 0.0170

PHE 2357 PHE 2358 0.0113

PHE 2358 ILE 2359 0.0122

ILE 2359 MET 2360 0.0146

MET 2360 LEU 2361 0.0112

LEU 2361 SER 2362 0.0151

SER 2362 SER 2363 0.0134

SER 2363 LEU 2364 0.0108

LEU 2364 ALA 2365 0.1084

ALA 2365 GLY 2366 0.0015

GLY 2366 VAL 2367 0.0062

VAL 2367 SER 2368 0.0001

SER 2368 GLY 2369 0.0060

GLY 2369 SER 2370 0.0029

SER 2370 ALA 2371 0.0035

ALA 2371 SER 2372 0.0061

SER 2372 GLN 2373 0.0011

GLN 2373 ALA 2374 0.0043

ALA 2374 ASN 2375 0.0039

ASN 2375 TYR 2376 0.0064

TYR 2376 THR 2377 0.0062

THR 2377 ALA 2378 0.0030

ALA 2378 GLY 2379 0.0054

GLY 2379 GLY 2380 0.0064

GLY 2380 ALA 2381 -0.0129

ALA 2381 TYR 2382 0.0034

TYR 2382 GLN 2383 0.0010

GLN 2383 ASP 2384 0.0029

ASP 2384 ALA 2385 0.0024

ALA 2385 LEU 2386 0.0037

LEU 2386 ALA 2387 0.0001

ALA 2387 LYS 2388 0.0036

LYS 2388 TYR 2389 0.0019

TYR 2389 ARG 2390 0.0023

ARG 2390 ARG 2391 0.0015

ARG 2391 ALA 2392 0.0025

ALA 2392 GLN 2393 0.0037

GLN 2393 GLY 2394 0.0001

GLY 2394 LEU 2395 0.0038

LEU 2395 SER 2396 0.0023

SER 2396 ALA 2397 0.0190

ALA 2397 VAL 2398 0.0067

VAL 2398 SER 2399 0.0021

SER 2399 ILE 2400 0.0065

ILE 2400 ASP 2401 0.0019

ASP 2401 LEU 2402 0.0061

LEU 2402 GLY 2403 0.0062

GLY 2403 MET 2404 0.0067

MET 2404 VAL 2405 0.0025

VAL 2405 GLN 2406 0.0066

GLN 2406 SER 2407 0.0040

SER 2407 VAL 2408 0.0067

VAL 2408 GLY 2409 0.0022

GLY 2409 TYR 2410 0.0004

TYR 2410 VAL 2411 0.0069

VAL 2411 ALA 2412 0.0032

ALA 2412 GLU 2413 0.0068

GLU 2413 THR 2414 0.0004

THR 2414 LYS 2415 0.0081

LYS 2415 GLY 2416 0.0029

GLY 2416 VAL 2417 0.0104

VAL 2417 ALA 2418 0.0094

ALA 2418 GLU 2419 0.0043

GLU 2419 ARG 2420 0.0062

ARG 2420 LEU 2421 0.0087

LEU 2421 VAL 2422 0.0103

VAL 2422 ARG 2423 0.0006

ARG 2423 MET 2424 0.0103

MET 2424 GLY 2425 0.0088

GLY 2425 TYR 2426 0.0013

TYR 2426 SER 2427 0.0045

SER 2427 PRO 2428 0.0034

PRO 2428 ILE 2429 0.0010

ILE 2429 SER 2430 0.0047

SER 2430 GLU 2431 0.0159

GLU 2431 MET 2432 0.0110

MET 2432 GLU 2433 0.0113

GLU 2433 VAL 2434 0.0174

VAL 2434 LEU 2435 0.0037

LEU 2435 LYS 2436 0.0198

LYS 2436 ILE 2437 0.0053

ILE 2437 VAL 2438 0.0194

VAL 2438 GLU 2439 0.0028

GLU 2439 HIS 2440 0.0179

HIS 2440 ALA 2441 0.0115

ALA 2441 ILE 2442 0.0082

ILE 2442 THR 2443 0.0131

THR 2443 ASN 2444 0.0113

ASN 2444 PRO 2445 -0.2078

PRO 2445 PRO 2446 0.0045

PRO 2446 PRO 2447 0.0047

PRO 2447 GLU 2448 0.0020

GLU 2448 ALA 2449 0.0020

ALA 2449 SER 2450 0.0049

SER 2450 SER 2451 0.0011

SER 2451 ALA 2452 0.0044

ALA 2452 GLN 2453 0.0047

GLN 2453 ILE 2454 0.0012

ILE 2454 ILE 2455 0.0047

ILE 2455 THR 2456 0.0025

THR 2456 GLY 2457 0.0043

GLY 2457 ILE 2458 0.0049

ILE 2458 SER 2459 0.0019

SER 2459 THR 2460 0.0043

THR 2460 LYS 2461 0.1321

LYS 2461 PRO 2462 0.0189

PRO 2462 GLY 2463 0.0261

GLY 2463 ARG 2464 0.0246

ARG 2464 HIS 2465 0.0027

HIS 2465 TRP 2466 0.0269

TRP 2466 THR 2467 0.0261

THR 2467 GLU 2468 0.0206

GLU 2468 SER 2469 0.0090

SER 2469 SER 2470 0.0143

SER 2470 TRP 2471 0.0193

TRP 2471 LEU 2472 0.0104

LEU 2472 GLN 2473 0.0267

GLN 2473 ASP 2474 0.0065

ASP 2474 ALA 2475 0.0267

ALA 2475 ARG 2476 0.0237

ARG 2476 PHE 2477 0.0123

PHE 2477 ALA 2478 0.0342

ALA 2478 THR 2479 0.0372

THR 2479 LEU 2480 0.0306

LEU 2480 ARG 2481 0.0327

ARG 2481 GLU 2482 0.0326

GLU 2482 ARG 2483 0.0367

ARG 2483 ALA 2484 0.0330

ALA 2484 ARG 2485 0.0336

ARG 2485 ASP 2486 0.0363

ASP 2486 VAL 2487 0.0336

VAL 2487 LYS 2488 0.0333

LYS 2488 GLU 2489 0.0362

GLU 2489 LEU 2490 0.0371

LEU 2490 SER 2491 0.0261

SER 2491 ASN 2492 0.0332

ASN 2492 SER 2493 0.0733

SER 2493 GLN 2494 0.0992

GLN 2494 ASN 989 0.0310

ASN 989 LYS 990 0.0431

LYS 990 ALA 991 0.0010

ALA 991 HIS 992 0.0431

HIS 992 ARG 993 0.0229

ARG 993 GLN 994 0.0330

GLN 994 ARG 995 0.0103

ARG 995 VAL 996 0.0343

VAL 996 HIS 997 0.0190

HIS 997 PRO 998 0.0427

PRO 998 PRO 999 0.0282

PRO 999 HIS 1000 0.0100

HIS 1000 ASP 1001 0.0291

ASP 1001 LEU 1002 0.0173

LEU 1002 LEU 1003 0.0359

LEU 1003 GLY 1004 0.0105

GLY 1004 SER 1005 -0.2250

SER 1005 LEU 1006 0.0184

LEU 1006 ILE 1007 0.0184

ILE 1007 VAL 1008 0.0109

VAL 1008 GLY 1009 0.0197

GLY 1009 ARG 1010 -0.0000

ARG 1010 ASP 1011 0.0134

ASP 1011 LEU 1012 0.0189

LEU 1012 ARG 1013 0.0034

ARG 1013 GLU 1014 0.0197

GLU 1014 PRO 1015 0.0124

PRO 1015 THR 1016 0.0194

THR 1016 TRP 1017 0.0167

TRP 1017 ARG 1018 0.0158

ARG 1018 HIS 1019 0.0201

HIS 1019 PHE 1020 0.0163

PHE 1020 ILE 1021 0.1094

ILE 1021 ARG 1022 0.0545

ARG 1022 VAL 1023 0.0062

VAL 1023 GLN 1024 0.0559

GLN 1024 ASP 1025 0.0453

ASP 1025 ILE 1026 0.0311

ILE 1026 PRO 1027 0.0151

PRO 1027 TRP 1028 0.0401

TRP 1028 ILE 1029 0.0561

ILE 1029 ARG 1030 0.0380

ARG 1030 ASP 1031 0.0267

ASP 1031 HIS 1032 0.0570

HIS 1032 VAL 1033 0.0567

VAL 1033 VAL 1034 0.0592

VAL 1034 GLN 1035 0.0543

GLN 1035 SER 1036 0.0591

SER 1036 ALA 1037 -0.0442

ALA 1037 LEU 1038 0.0286

LEU 1038 VAL 1039 0.0345

VAL 1039 TYR 1040 0.0205

TYR 1040 PRO 1041 0.0360

PRO 1041 GLY 1042 0.0366

GLY 1042 ALA 1043 0.0410

ALA 1043 GLY 1044 0.0245

GLY 1044 PHE 1045 0.0247

PHE 1045 ILE 1046 0.0416

ILE 1046 CYS 1047 0.0410

CYS 1047 MET 1048 0.0185

MET 1048 ALA 1049 0.0336

ALA 1049 MET 1050 0.0413

MET 1050 GLU 1051 0.0363

GLU 1051 ALA 1052 0.0193

ALA 1052 MET 1053 0.1577

MET 1053 VAL 1054 0.0263

VAL 1054 GLN 1055 0.0185

GLN 1055 LEU 1056 0.0130

LEU 1056 HIS 1057 0.0285

HIS 1057 GLU 1058 0.0287

GLU 1058 LEU 1059 0.0097

LEU 1059 ARG 1060 0.0213

ARG 1060 ASP 1061 0.0269

ASP 1061 SER 1062 0.0272

SER 1062 GLN 1063 0.0268

GLN 1063 SER 1064 0.0010

SER 1064 ARG 1065 0.0270

ARG 1065 LYS 1066 -0.0001

LYS 1066 VAL 1067 0.0240

VAL 1067 ALA 1068 0.0173

ALA 1068 GLY 1069 0.1493

GLY 1069 TYR 1070 0.0343

TYR 1070 ARG 1071 0.0338

ARG 1071 LEU 1072 0.0325

LEU 1072 ALA 1073 0.0341

ALA 1073 GLU 1074 0.0325

GLU 1074 VAL 1075 0.0262

VAL 1075 ASP 1076 0.0307

ASP 1076 ILE 1077 0.0219

ILE 1077 LEU 1078 0.0327

LEU 1078 ARG 1079 0.0255

ARG 1079 ALA 1080 0.0215

ALA 1080 MET 1081 0.0284

MET 1081 LEU 1082 0.0216

LEU 1082 ILE 1083 0.0340

ILE 1083 PRO 1084 0.0330

PRO 1084 ASP 1085 0.1445

ASP 1085 THR 1086 0.0014

THR 1086 SER 1087 0.0079

SER 1087 GLU 1088 0.0162

GLU 1088 GLY 1089 0.0003

GLY 1089 LEU 1090 0.0121

LEU 1090 GLU 1091 0.0154

GLU 1091 ALA 1092 0.0048

ALA 1092 HIS 1093 0.0160

HIS 1093 ILE 1094 0.0086

ILE 1094 SER 1095 0.0163

SER 1095 LEU 1096 0.0110

LEU 1096 ARG 1097 0.0157

ARG 1097 PRO 1098 0.0120

PRO 1098 CYS 1099 0.0042

CYS 1099 SER 1100 0.0161

SER 1100 THR 1101 -0.2078

THR 1101 LYS 1102 0.0010

LYS 1102 LEU 1103 0.0005

LEU 1103 LEU 1104 0.0015

LEU 1104 LEU 1105 0.0003

LEU 1105 THR 1106 0.0016

THR 1106 ASN 1107 0.0012

ASN 1107 GLU 1108 0.0017

GLU 1108 TRP 1109 0.0017

TRP 1109 TYR 1110 0.0017

TYR 1110 ASP 1111 0.0015

ASP 1111 PHE 1112 0.0009

PHE 1112 CYS 1113 0.0016

CYS 1113 VAL 1114 0.0009

VAL 1114 SER 1115 0.0016

SER 1115 SER 1116 0.0016

SER 1116 VAL 1117 0.0317

VAL 1117 GLY 1118 0.0075

GLY 1118 ASP 1119 0.0043

ASP 1119 ASP 1120 0.0044

ASP 1120 ASP 1121 0.0076

ASP 1121 LYS 1122 0.0059

LYS 1122 PHE 1123 0.0034

PHE 1123 VAL 1124 0.0016

VAL 1124 ASP 1125 0.0044

ASP 1125 HIS 1126 0.0007

HIS 1126 CYS 1127 0.0061

CYS 1127 ARG 1128 0.0071

ARG 1128 GLY 1129 0.0056

GLY 1129 ARG 1130 0.0075

ARG 1130 ILE 1131 0.0066

ILE 1131 THR 1132 0.0074

THR 1132 ILE 1133 0.2639

ILE 1133 GLU 1134 0.0470

GLU 1134 PHE 1135 0.0440

PHE 1135 ASP 1136 0.0562

ASP 1136 THR 1137 0.0097

THR 1137 SER 1138 0.0438

SER 1138 GLY 1139 0.0530

GLY 1139 SER 1140 0.0401

SER 1140 ALA 1141 0.0578

ALA 1141 ASP 1142 0.0048

ASP 1142 THR 1143 0.0620

THR 1143 PRO 1144 0.0378

PRO 1144 ARG 1145 0.0171

ARG 1145 THR 1146 0.0546

THR 1146 SER 1147 0.0346

SER 1147 LEU 1148 0.0109

LEU 1148 ARG 1149 0.0138

ARG 1149 GLU 1150 0.0804

GLU 1150 ARG 1151 0.0750

ARG 1151 SER 1152 0.0502

SER 1152 ARG 1153 0.0289

ARG 1153 SER 1154 0.0795

SER 1154 THR 1155 0.0185

THR 1155 GLY 1156 0.0803

GLY 1156 LEU 1157 0.0776

LEU 1157 MET 1158 0.0362

MET 1158 ARG 1159 0.0803

ARG 1159 SER 1160 0.0688

SER 1160 VAL 1161 0.0451

VAL 1161 ASP 1162 0.0683

ASP 1162 PRO 1163 0.0009

PRO 1163 SER 1164 0.0804

SER 1164 ASN 1165 0.0978

ASN 1165 LEU 1166 0.0162

LEU 1166 TYR 1167 0.0665

TYR 1167 SER 1168 0.0410

SER 1168 PHE 1169 0.0795

PHE 1169 LEU 1170 0.0004

LEU 1170 ARG 1171 0.0798

ARG 1171 ALA 1172 0.0534

ALA 1172 GLN 1173 0.0412

GLN 1173 GLY 1174 0.0473

GLY 1174 ILE 1175 0.0690

ILE 1175 TYR 1176 0.0785

TYR 1176 HIS 1177 0.0770

HIS 1177 GLY 1178 0.0792

GLY 1178 PRO 1179 0.0750

PRO 1179 ILE 1180 0.0181

ILE 1180 PHE 1181 0.0771

PHE 1181 GLN 1182 0.0069

GLN 1182 ASN 1183 0.0835

ASN 1183 LEU 1184 0.0572

LEU 1184 LYS 1185 0.0392

LYS 1185 THR 1186 0.0705

THR 1186 ILE 1187 0.0860

ILE 1187 SER 1188 0.0756

SER 1188 SER 1189 0.0847

SER 1189 ARG 1190 0.0829

ARG 1190 LYS 1191 0.0808

LYS 1191 ASP 1192 0.0097

ASP 1192 HIS 1193 0.0841

HIS 1193 SER 1194 0.0839

SER 1194 GLU 1195 0.0856

GLU 1195 SER 1196 0.0838

SER 1196 SER 1197 0.0344

SER 1197 PHE 1198 0.0589

PHE 1198 VAL 1199 0.0653

VAL 1199 VAL 1200 0.0163

VAL 1200 ALA 1201 0.0707

ALA 1201 ASN 1202 0.0689

ASN 1202 THR 1203 0.0426

THR 1203 ALA 1204 0.0591

ALA 1204 SER 1205 0.0203

SER 1205 VAL 1206 0.0711

VAL 1206 MET 1207 0.0032

MET 1207 PRO 1208 0.0650

PRO 1208 ASN 1209 0.0722

ASN 1209 GLY 1210 0.0652

GLY 1210 PHE 1211 0.0071

PHE 1211 GLN 1212 0.0685

GLN 1212 SER 1213 0.1529

SER 1213 PRO 1214 0.0609

PRO 1214 HIS 1215 0.0594

HIS 1215 VAL 1216 0.0604

VAL 1216 ILE 1217 0.0180

ILE 1217 HIS 1218 0.0484

HIS 1218 PRO 1219 0.0586

PRO 1219 THR 1220 0.0038

THR 1220 THR 1221 0.0608

THR 1221 LEU 1222 0.0466

LEU 1222 ASP 1223 0.0434

ASP 1223 SER 1224 0.0202

SER 1224 ILE 1225 0.0544

ILE 1225 PHE 1226 0.0599

PHE 1226 GLN 1227 0.0086

GLN 1227 GLY 1228 0.0566

GLY 1228 ALA 1229 0.0160

ALA 1229 TYR 1230 0.0291

TYR 1230 THR 1231 0.0600

THR 1231 ALA 1232 0.0803

ALA 1232 LEU 1233 0.0757

LEU 1233 PRO 1234 0.0157

PRO 1234 GLY 1235 0.0483

GLY 1235 ALA 1236 0.0413

ALA 1236 GLY 1237 0.0781

GLY 1237 LEU 1238 0.0238

LEU 1238 ASP 1239 0.0855

ASP 1239 GLN 1240 0.0244

GLN 1240 ASN 1241 0.0862

ASN 1241 THR 1242 0.0241

THR 1242 ALA 1243 0.0587

ALA 1243 MET 1244 0.0416

MET 1244 ILE 1245 0.0399

ILE 1245 PRO 1246 0.0257

PRO 1246 ARG 1247 0.0390

ARG 1247 SER 1248 0.0391

SER 1248 ILE 1249 0.0645

ILE 1249 GLN 1250 0.0470

GLN 1250 GLU 1251 0.0642

GLU 1251 LEU 1252 0.0632

LEU 1252 TYR 1253 0.0623

TYR 1253 LEU 1254 0.0657

LEU 1254 SER 1255 0.0652

SER 1255 SER 1256 0.0579

SER 1256 ALA 1257 0.0354

ALA 1257 LEU 1258 0.0378

LEU 1258 THR 1259 0.0623

THR 1259 SER 1260 0.0625

SER 1260 ASP 1261 0.1488

ASP 1261 VAL 1262 0.0316

VAL 1262 GLY 1263 0.0330

GLY 1263 GLN 1264 0.0703

GLN 1264 CYS 1265 0.0706

CYS 1265 LEU 1266 0.0653

LEU 1266 VAL 1267 0.0816

VAL 1267 SER 1268 0.0823

SER 1268 ASP 1269 0.0903

ASP 1269 THR 1270 0.0902

THR 1270 SER 1271 0.0894

SER 1271 LEU 1272 0.0893

LEU 1272 ILE 1273 0.0397

ILE 1273 ARG 1274 0.0837

ARG 1274 TYR 1275 0.0480

TYR 1275 ASP 1276 0.0891

ASP 1276 GLY 1277 0.0792

GLY 1277 GLN 1278 0.0452

GLN 1278 SER 1279 0.0546

SER 1279 PHE 1280 0.0921

PHE 1280 THR 1281 0.0445

THR 1281 VAL 1282 0.0920

VAL 1282 ASN 1283 0.0667

ASN 1283 VAL 1284 0.0895

VAL 1284 ASP 1285 0.0875

ASP 1285 VAL 1286 0.0898

VAL 1286 SER 1287 0.0922

SER 1287 SER 1288 0.0877

SER 1288 LYS 1289 0.0154

LYS 1289 ALA 1290 0.0815

ALA 1290 ASP 1291 0.0533

ASP 1291 SER 1292 0.0818

SER 1292 GLU 1293 0.0703

GLU 1293 HIS 1294 0.0835

HIS 1294 THR 1295 0.0093

THR 1295 PRO 1296 0.0901

PRO 1296 VAL 1297 0.0790

VAL 1297 LEU 1298 0.0893

LEU 1298 GLU 1299 0.0898

GLU 1299 ILE 1300 0.0866

ILE 1300 LYS 1301 0.0888

LYS 1301 GLY 1302 0.0790

GLY 1302 LEU 1303 0.0728

LEU 1303 ARG 1304 0.0811

ARG 1304 ASN 1305 0.0444

ASN 1305 GLN 1306 0.0870

GLN 1306 SER 1307 0.0413

SER 1307 VAL 1308 0.0888

VAL 1308 GLY 1309 -0.0419

GLY 1309 GLN 1310 0.0304

GLN 1310 MET 1311 0.0572

MET 1311 ALA 1312 0.0201

ALA 1312 PRO 1313 0.0475

PRO 1313 GLN 1314 0.0541

GLN 1314 PRO 1315 0.0238

PRO 1315 GLY 1316 0.0527

GLY 1316 ASP 1317 0.0524

ASP 1317 SER 1318 0.0232

SER 1318 SER 1319 0.0558

SER 1319 ASN 1320 0.0240

ASN 1320 ASN 1321 0.0334

ASN 1321 ASP 1322 0.0324

ASP 1322 LEU 1323 0.0572

LEU 1323 CYS 1324 0.0024

CYS 1324 PHE 1325 0.1699

PHE 1325 LYS 1326 0.0196

LYS 1326 LEU 1327 0.0277

LEU 1327 ASP 1328 0.0530

ASP 1328 TRP 1329 0.0230

TRP 1329 ALA 1330 0.0527

ALA 1330 PRO 1331 0.0391

PRO 1331 ASP 1332 0.0526

ASP 1332 ILE 1333 0.0433

ILE 1333 SER 1334 0.0450

SER 1334 SER 1335 0.0086

SER 1335 VAL 1336 0.0521

VAL 1336 LYS 1337 0.0364

LYS 1337 GLN 1338 0.0434

GLN 1338 GLU 1339 0.0333

GLU 1339 ARG 1340 0.0503

ARG 1340 LEU 1341 -0.1317

LEU 1341 LYS 1342 0.0071

LYS 1342 GLU 1343 0.0351

GLU 1343 LYS 1344 0.0048

LYS 1344 PHE 1345 0.0354

PHE 1345 GLY 1346 0.0019

GLY 1346 PHE 1347 0.0323

PHE 1347 PRO 1348 0.0115

PRO 1348 LEU 1349 0.0232

LEU 1349 ASP 1350 0.0334

ASP 1350 PRO 1351 0.0101

PRO 1351 THR 1352 0.0292

THR 1352 GLU 1353 0.0337

GLU 1353 ALA 1354 0.0052

ALA 1354 ASP 1355 0.0317

ASP 1355 ILE 1356 0.0199

ILE 1356 ILE 1357 0.0545

ILE 1357 MET 1358 0.0300

MET 1358 GLY 1359 0.1217

GLY 1359 LEU 1360 0.0743

LEU 1360 ARG 1361 0.0813

ARG 1361 GLN 1362 0.1123

GLN 1362 ALA 1363 0.0460

ALA 1363 CYS 1364 0.1351

CYS 1364 ILE 1365 0.0316

ILE 1365 HIS 1366 0.1405

HIS 1366 PHE 1367 0.0319

PHE 1367 ILE 1368 0.1272

ILE 1368 HIS 1369 0.0491

HIS 1369 ARG 1370 0.1074

ARG 1370 SER 1371 0.0793

SER 1371 LEU 1372 0.0817

LEU 1372 GLN 1373 0.1425

GLN 1373 SER 1374 0.0449

SER 1374 LEU 1375 0.1248

LEU 1375 THR 1376 0.1440

THR 1376 ALA 1377 0.1452

ALA 1377 PRO 1378 0.0157

PRO 1378 ASP 1379 0.1362

ASP 1379 ARG 1380 0.1225

ARG 1380 ASP 1381 0.1178

ASP 1381 GLN 1382 0.0354

GLN 1382 LEU 1383 0.1427

LEU 1383 ASP 1384 0.0826

ASP 1384 TRP 1385 0.1316

TRP 1385 HIS 1386 0.1454

HIS 1386 GLN 1387 0.1206

GLN 1387 LYS 1388 0.0818

LYS 1388 ARG 1389 0.3180

ARG 1389 PHE 1390 0.1330

PHE 1390 TYR 1391 0.0883

TYR 1391 ASP 1392 0.0968

ASP 1392 TRP 1393 0.1342

TRP 1393 MET 1394 0.1257

MET 1394 VAL 1395 0.0654

VAL 1395 LEU 1396 0.1239

LEU 1396 GLN 1397 0.1343

GLN 1397 ILE 1398 0.0898

ILE 1398 GLN 1399 0.0898

GLN 1399 LEU 1400 0.1344

LEU 1400 ALA 1401 0.1299

ALA 1401 GLU 1402 0.0614

GLU 1402 GLU 1403 0.1202

GLU 1403 ASP 1404 0.1343

ASP 1404 ARG 1405 0.1949

ARG 1405 LEU 1406 0.0598

LEU 1406 ALA 1407 0.1419

ALA 1407 PRO 1408 0.0253

PRO 1408 ASN 1409 0.1710

ASN 1409 SER 1410 0.0562

SER 1410 SER 1411 0.1370

SER 1411 ALA 1412 0.1784

ALA 1412 TRP 1413 0.0007

TRP 1413 LEU 1414 0.1782

LEU 1414 GLN 1415 0.1331

GLN 1415 CYS 1416 0.1182

CYS 1416 SER 1417 0.1761

SER 1417 SER 1418 0.0293

SER 1418 SER 1419 0.1782

SER 1419 ASP 1420 0.1682

ASP 1420 GLU 1421 0.1713

GLU 1421 GLN 1422 0.0615

GLN 1422 LYS 1423 0.1634

LYS 1423 LEU 1424 0.1647

LEU 1424 LEU 1425 0.0477

LEU 1425 GLU 1426 0.1317

GLU 1426 ASN 1427 0.1431

ASN 1427 VAL 1428 0.1660

VAL 1428 ARG 1429 0.0190

ARG 1429 ALA 1430 0.1668

ALA 1430 SER 1431 0.1345

SER 1431 SER 1432 0.1206

SER 1432 VAL 1433 0.0812

VAL 1433 ASN 1434 0.0885

ASN 1434 GLY 1435 0.1480

GLY 1435 GLN 1436 0.0357

GLN 1436 MET 1437 0.1181

MET 1437 VAL 1438 0.0267

VAL 1438 VAL 1439 0.1534

VAL 1439 HIS 1440 0.0228

HIS 1440 VAL 1441 0.1494

VAL 1441 GLY 1442 0.0173

GLY 1442 LYS 1443 0.1466

LYS 1443 SER 1444 0.0932

SER 1444 MET 1445 0.1082

MET 1445 LEU 1446 0.1462

LEU 1446 ALA 1447 0.0137

ALA 1447 ILE 1448 0.1454

ILE 1448 LEU 1449 0.0867

LEU 1449 ARG 1450 0.1334

ARG 1450 HIS 1451 0.0280

HIS 1451 GLU 1452 0.1422

GLU 1452 ILE 1453 0.0917

ILE 1453 ALA 1454 0.1484

ALA 1454 PRO 1455 0.0787

PRO 1455 LEU 1456 0.1074

LEU 1456 GLU 1457 0.0887

GLU 1457 LEU 1458 0.0736

LEU 1458 MET 1459 0.1377

MET 1459 LEU 1460 0.0290

LEU 1460 GLN 1461 0.1510

GLN 1461 ASP 1462 0.1526

ASP 1462 LYS 1463 0.1521

LYS 1463 LEU 1464 0.0075

LEU 1464 LEU 1465 0.1521

LEU 1465 TYR 1466 0.1276

TYR 1466 ARG 1467 0.0940

ARG 1467 TYR 1468 0.0735

TYR 1468 TYR 1469 -0.0885

TYR 1469 THR 1470 0.0166

THR 1470 ASP 1471 0.0137

ASP 1471 ALA 1472 0.0036

ALA 1472 ILE 1473 0.0060

ILE 1473 LYS 1474 0.0176

LYS 1474 TRP 1475 0.0041

TRP 1475 ASP 1476 0.0151

ASP 1476 ARG 1477 0.0079

ARG 1477 SER 1478 0.0187

SER 1478 TYR 1479 0.0002

TYR 1479 GLN 1480 0.0184

GLN 1480 GLN 1481 0.0112

GLN 1481 ILE 1482 0.0100

ILE 1482 ASP 1483 0.0089

ASP 1483 GLN 1484 0.0137

GLN 1484 LEU 1485 -0.3662

LEU 1485 VAL 1486 0.0050

VAL 1486 LYS 1487 0.0101

LYS 1487 LEU 1488 0.0131

LEU 1488 HIS 1489 0.0014

HIS 1489 ALA 1490 0.0118

ALA 1490 HIS 1491 0.0088

HIS 1491 LYS 1492 0.0116

LYS 1492 CYS 1493 0.0015

CYS 1493 PRO 1494 0.0132

PRO 1494 THR 1495 0.0003

THR 1495 ALA 1496 0.0132

ALA 1496 LYS 1497 0.0059

LYS 1497 ILE 1498 0.0102

ILE 1498 ILE 1499 0.0118

ILE 1499 GLU 1500 0.0101

GLU 1500 ILE 1501 -0.0159

ILE 1501 GLY 1502 0.0017

GLY 1502 ALA 1503 0.0002

ALA 1503 GLY 1504 0.0017

GLY 1504 THR 1505 -0.0001

THR 1505 GLY 1506 0.0017

GLY 1506 GLY 1507 0.0013

GLY 1507 CYS 1508 0.0013

CYS 1508 THR 1509 0.0020

THR 1509 ARG 1510 -0.0000

ARG 1510 ALA 1511 0.0015

ALA 1511 VAL 1512 0.0007

VAL 1512 LEU 1513 0.0016

LEU 1513 ASP 1514 0.0003

ASP 1514 ALA 1515 0.0013

ALA 1515 LEU 1516 0.0013

LEU 1516 SER 1517 0.2046

SER 1517 ASN 1518 0.0031

ASN 1518 GLN 1519 0.0030

GLN 1519 GLY 1520 0.0018

GLY 1520 ILE 1521 0.0017

ILE 1521 ALA 1522 0.0031

ALA 1522 ARG 1523 0.0033

ARG 1523 CYS 1524 0.0026

CYS 1524 ALA 1525 0.0003

ALA 1525 GLN 1526 0.0028

GLN 1526 TYR 1527 0.0010

TYR 1527 ASP 1528 0.0030

ASP 1528 PHE 1529 0.0014

PHE 1529 THR 1530 0.0030

THR 1530 ASP 1531 0.0023

ASP 1531 VAL 1532 0.0029

VAL 1532 SER 1533 0.1247

SER 1533 SER 1534 0.0035

SER 1534 GLY 1535 0.0011

GLY 1535 PHE 1536 0.0037

PHE 1536 PHE 1537 0.0033

PHE 1537 GLU 1538 0.0011

GLU 1538 ALA 1539 0.0039

ALA 1539 ALA 1540 0.0004

ALA 1540 GLN 1541 0.0039

GLN 1541 GLN 1542 0.0014

GLN 1542 LYS 1543 0.0035

LYS 1543 PHE 1544 0.0009

PHE 1544 ALA 1545 0.0036

ALA 1545 ALA 1546 0.0029

ALA 1546 PHE 1547 0.0010

PHE 1547 ASP 1548 0.0039

ASP 1548 ASP 1549 0.0948

ASP 1549 VAL 1550 0.0036

VAL 1550 ILE 1551 0.0022

ILE 1551 ARG 1552 -0.0000

ARG 1552 PHE 1553 0.0024

PHE 1553 GLN 1554 0.0014

GLN 1554 LYS 1555 0.0025

LYS 1555 LEU 1556 0.0034

LEU 1556 ASP 1557 0.0027

ASP 1557 ILE 1558 0.0026

ILE 1558 GLU 1559 0.0017

GLU 1559 LYS 1560 0.0026

LYS 1560 ASP 1561 0.0037

ASP 1561 ILE 1562 0.0013

ILE 1562 GLU 1563 0.0032

GLU 1563 MET 1564 0.0013

MET 1564 GLN 1565 0.0403

GLN 1565 GLY 1566 0.0050

GLY 1566 PHE 1567 0.0006

PHE 1567 GLU 1568 0.0034

GLU 1568 CYS 1569 0.0013

CYS 1569 GLY 1570 0.0016

GLY 1570 SER 1571 0.0038

SER 1571 TYR 1572 0.0045

TYR 1572 ASP 1573 0.0017

ASP 1573 LEU 1574 0.0052

LEU 1574 VAL 1575 0.0041

VAL 1575 ILE 1576 0.0050

ILE 1576 ALA 1577 0.0051

ALA 1577 SER 1578 0.0050

SER 1578 GLN 1579 0.0049

GLN 1579 VAL 1580 0.0034

VAL 1580 LEU 1581 -0.1922

LEU 1581 HIS 1582 0.0164

HIS 1582 ALA 1583 0.0060

ALA 1583 THR 1584 0.0144

THR 1584 GLY 1585 0.0182

GLY 1585 LYS 1586 0.0179

LYS 1586 MET 1587 0.0100

MET 1587 GLU 1588 0.0194

GLU 1588 HIS 1589 0.0019

HIS 1589 THR 1590 0.0185

THR 1590 MET 1591 0.0117

MET 1591 ALA 1592 0.0115

ALA 1592 ASN 1593 0.0131

ASN 1593 VAL 1594 0.0085

VAL 1594 ARG 1595 0.0193

ARG 1595 LYS 1596 0.0024

LYS 1596 LEU 1597 0.1696

LEU 1597 LEU 1598 0.0032

LEU 1598 LYS 1599 0.0088

LYS 1599 PRO 1600 0.0031

PRO 1600 GLY 1601 0.0042

GLY 1601 GLY 1602 0.0061

GLY 1602 LYS 1603 0.0073

LYS 1603 LEU 1604 0.0088

LEU 1604 LEU 1605 0.0082

LEU 1605 LEU 1606 0.0087

LEU 1606 VAL 1607 0.0087

VAL 1607 GLU 1608 0.0088

GLU 1608 THR 1609 0.0074

THR 1609 THR 1610 0.0032

THR 1610 ARG 1611 0.0072

ARG 1611 ASP 1612 0.0062

ASP 1612 GLU 1613 0.3239

GLU 1613 MET 1614 0.0921

MET 1614 ASP 1615 0.0438

ASP 1615 LEU 1616 0.0539

LEU 1616 GLN 1617 0.0845

GLN 1617 LEU 1618 0.0941

LEU 1618 VAL 1619 0.0136

VAL 1619 PHE 1620 0.0767

PHE 1620 GLY 1621 0.0625

GLY 1621 LEU 1622 0.0708

LEU 1622 LEU 1623 0.0367

LEU 1623 PRO 1624 0.0925

PRO 1624 GLY 1625 0.0890

GLY 1625 TRP 1626 0.0137

TRP 1626 TRP 1627 0.0816

TRP 1627 LEU 1628 0.0564

LEU 1628 SER 1629 0.1770

SER 1629 SER 1630 0.0730

SER 1630 GLU 1631 0.0342

GLU 1631 GLU 1632 0.0135

GLU 1632 GLU 1633 0.0659

GLU 1633 ARG 1634 0.0340

ARG 1634 GLN 1635 0.0754

GLN 1635 MET 1636 0.0538

MET 1636 SER 1637 0.0616

SER 1637 PRO 1638 0.0208

PRO 1638 SER 1639 0.0590

SER 1639 LEU 1640 0.0632

LEU 1640 SER 1641 0.0265

SER 1641 THR 1642 0.0743

THR 1642 ASN 1643 0.0562

ASN 1643 SER 1644 0.0448

SER 1644 TRP 1645 0.3483

TRP 1645 GLU 1646 0.0207

GLU 1646 LYS 1647 0.0214

LYS 1647 VAL 1648 0.0046

VAL 1648 LEU 1649 0.0227

LEU 1649 LYS 1650 0.0222

LYS 1650 LYS 1651 0.0149

LYS 1651 THR 1652 0.0101

THR 1652 GLY 1653 0.0232

GLY 1653 PHE 1654 0.0127

PHE 1654 ASP 1655 0.0083

ASP 1655 GLY 1656 0.0149

GLY 1656 LEU 1657 0.0190

LEU 1657 ASP 1658 0.0231

ASP 1658 ILE 1659 0.0190

ILE 1659 GLU 1660 0.0196

GLU 1660 LEU 1661 0.0534

LEU 1661 ARG 1662 0.0156

ARG 1662 ASP 1663 0.0187

ASP 1663 CYS 1664 0.0060

CYS 1664 ASP 1665 0.0084

ASP 1665 SER 1666 0.0114

SER 1666 ASP 1667 0.0170

ASP 1667 GLU 1668 0.0204

GLU 1668 PHE 1669 0.0043

PHE 1669 TYR 1670 0.0108

TYR 1670 SER 1671 0.0141

SER 1671 PHE 1672 0.0063

PHE 1672 SER 1673 0.0206

SER 1673 VAL 1674 0.0058

VAL 1674 MET 1675 0.0207

MET 1675 MET 1676 0.0140

MET 1676 ALA 1677 0.2305

ALA 1677 THR 1678 0.0609

THR 1678 ALA 1679 0.0595

ALA 1679 SER 1680 0.0808

SER 1680 SER 1681 0.0626

SER 1681 THR 1682 0.0899

THR 1682 ILE 1683 0.0881

ILE 1683 ALA 1684 0.0606

ALA 1684 SER 1685 0.0655

SER 1685 SER 1686 0.0638

SER 1686 SER 1687 0.0884

SER 1687 MET 1688 0.0888

MET 1688 ALA 1689 0.0752

ALA 1689 PHE 1690 0.0695

PHE 1690 ALA 1691 0.0843

ALA 1691 ILE 1692 0.0576

ILE 1692 VAL 1693 0.2711

VAL 1693 TYR 1694 0.0216

TYR 1694 GLY 1695 0.0287

GLY 1695 GLU 1696 0.0275

GLU 1696 VAL 1697 0.0025

VAL 1697 PRO 1698 0.0286

PRO 1698 LEU 1699 0.0244

LEU 1699 PRO 1700 0.0028

PRO 1700 ASP 1701 0.0309

ASP 1701 GLN 1702 0.0198

GLN 1702 PHE 1703 0.0187

PHE 1703 LEU 1704 0.0139

LEU 1704 ASP 1705 0.0240

ASP 1705 ASP 1706 0.0285

ASP 1706 MET 1707 0.0032

MET 1707 LYS 1708 0.0272

LYS 1708 THR 1709 0.0433

THR 1709 ALA 1710 0.0327

ALA 1710 ILE 1711 0.0023

ILE 1711 SER 1712 0.0344

SER 1712 SER 1713 0.0259

SER 1713 SER 1714 0.0131

SER 1714 ALA 1715 0.0177

ALA 1715 VAL 1716 0.0341

VAL 1716 SER 1717 0.0353

SER 1717 ASP 1718 0.0238

ASP 1718 PRO 1719 0.0295

PRO 1719 VAL 1720 0.0321

VAL 1720 VAL 1721 0.0301

VAL 1721 GLY 1722 0.0264

GLY 1722 HIS 1723 0.0336

HIS 1723 LEU 1724 0.0103

LEU 1724 ASP 1725 0.0993

ASP 1725 SER 1726 0.0194

SER 1726 ILE 1727 0.0218

ILE 1727 ASP 1728 0.0143

ASP 1728 ALA 1729 0.0221

ALA 1729 THR 1730 0.0133

THR 1730 GLY 1731 0.0216

GLY 1731 LYS 1732 0.0052

LYS 1732 PHE 1733 0.0203

PHE 1733 CYS 1734 0.0210

CYS 1734 ILE 1735 0.0124

ILE 1735 PHE 1736 0.0205

PHE 1736 ILE 1737 0.0102

ILE 1737 GLU 1738 0.0199

GLU 1738 ASP 1739 0.0142

ASP 1739 PRO 1740 0.0222

PRO 1740 GLU 1741 0.0940

GLU 1741 THR 1742 0.0036

THR 1742 ASP 1743 0.0082

ASP 1743 ILE 1744 0.0109

ILE 1744 LEU 1745 0.0082

LEU 1745 SER 1746 0.0166

SER 1746 SER 1747 0.0142

SER 1747 PRO 1748 0.0165

PRO 1748 ASP 1749 0.0153

ASP 1749 GLU 1750 0.0089

GLU 1750 LYS 1751 0.0087

LYS 1751 SER 1752 0.0095

SER 1752 TYR 1753 0.0076

TYR 1753 ALA 1754 0.0148

ALA 1754 SER 1755 0.0027

SER 1755 ILE 1756 0.0166

ILE 1756 GLN 1757 0.0093

GLN 1757 LYS 1758 0.0186

LYS 1758 LEU 1759 0.0085

LEU 1759 VAL 1760 0.0150

VAL 1760 THR 1761 0.0087

THR 1761 ARG 1762 0.0145

ARG 1762 CYS 1763 0.0090

CYS 1763 LYS 1764 0.0206

LYS 1764 GLY 1765 0.0172

GLY 1765 LEU 1766 0.0151

LEU 1766 ILE 1767 0.0092

ILE 1767 TRP 1768 0.0203

TRP 1768 VAL 1769 0.0045

VAL 1769 SER 1770 0.0202

SER 1770 ARG 1771 0.0132

ARG 1771 GLY 1772 0.0195

GLY 1772 GLY 1773 -0.0263

GLY 1773 ALA 1774 0.0146

ALA 1774 MET 1775 0.0126

MET 1775 HIS 1776 0.0130

HIS 1776 GLY 1777 0.0115

GLY 1777 THR 1778 0.0045

THR 1778 ARG 1779 0.0122

ARG 1779 PRO 1780 0.0008

PRO 1780 ASN 1781 0.0141

ASN 1781 SER 1782 0.0132

SER 1782 SER 1783 0.0070

SER 1783 LEU 1784 0.0074

LEU 1784 LYS 1785 0.0149

LYS 1785 THR 1786 0.0150

THR 1786 GLY 1787 0.0030

GLY 1787 LEU 1788 0.0142

LEU 1788 LEU 1789 0.0568

LEU 1789 ARG 1790 0.0141

ARG 1790 THR 1791 0.0103

THR 1791 LEU 1792 0.0206

LEU 1792 ARG 1793 0.0214

ARG 1793 LEU 1794 0.0020

LEU 1794 GLU 1795 0.0217

GLU 1795 TYR 1796 0.0183

TYR 1796 THR 1797 0.0213

THR 1797 GLU 1798 0.0199

GLU 1798 LYS 1799 0.0043

LYS 1799 ARG 1800 0.0093

ARG 1800 PHE 1801 0.0191

PHE 1801 ILE 1802 0.0078

ILE 1802 SER 1803 0.0157

SER 1803 LEU 1804 0.0022

LEU 1804 ASP 1805 0.0106

ASP 1805 LEU 1806 0.0003

LEU 1806 ASP 1807 0.0326

ASP 1807 SER 1808 0.0440

SER 1808 ALA 1809 0.0141

ALA 1809 ARG 1810 0.0307

ARG 1810 PRO 1811 0.0384

PRO 1811 GLN 1812 0.0255

GLN 1812 TRP 1813 0.0367

TRP 1813 ASN 1814 0.0297

ASN 1814 HIS 1815 0.0424

HIS 1815 ASP 1816 0.0336

ASP 1816 SER 1817 0.0135

SER 1817 ILE 1818 0.0432

ILE 1818 THR 1819 0.0432

THR 1819 THR 1820 0.0137

THR 1820 ILE 1821 -0.0345

ILE 1821 ASN 1822 0.0244

ASN 1822 GLU 1823 0.0274

GLU 1823 VAL 1824 0.0023

VAL 1824 LEU 1825 0.0260

LEU 1825 CYS 1826 0.0216

CYS 1826 GLY 1827 0.0210

GLY 1827 ALA 1828 0.0073

ALA 1828 LEU 1829 0.0263

LEU 1829 ALA 1830 0.0221

ALA 1830 GLN 1831 0.0105

GLN 1831 ASN 1832 0.0231

ASN 1832 ALA 1833 0.0033

ALA 1833 ASP 1834 0.0272

ASP 1834 SER 1835 0.0240

SER 1835 SER 1836 0.0073

SER 1836 ILE 1837 0.0486

ILE 1837 LYS 1838 0.0288

LYS 1838 ASP 1839 0.0336

ASP 1839 SER 1840 0.0548

SER 1840 GLU 1841 0.0412

GLU 1841 PHE 1842 0.0074

PHE 1842 ALA 1843 0.0288

ALA 1843 GLU 1844 0.0042

GLU 1844 GLN 1845 0.0466

GLN 1845 ASP 1846 0.0088

ASP 1846 GLY 1847 0.0554

GLY 1847 GLN 1848 0.0164

GLN 1848 LEU 1849 0.0140

LEU 1849 PHE 1850 0.0223

PHE 1850 VAL 1851 0.0021

VAL 1851 PRO 1852 0.0261

PRO 1852 ARG 1853 -0.1077

ARG 1853 ILE 1854 0.0536

ILE 1854 SER 1855 0.0178

SER 1855 CYS 1856 0.0482

CYS 1856 ASP 1857 0.0386

ASP 1857 ILE 1858 0.0263

ILE 1858 ALA 1859 0.0354

ALA 1859 ARG 1860 0.0268

ARG 1860 ASN 1861 0.0490

ASN 1861 GLU 1862 0.0062

GLU 1862 ASP 1863 0.0535

ASP 1863 LEU 1864 0.0132

LEU 1864 SER 1865 0.0502

SER 1865 SER 1866 0.0080

SER 1866 ASP 1867 0.0506

ASP 1867 SER 1868 0.0537

SER 1868 ASN 1869 -0.0940

ASN 1869 SER 1870 0.0080

SER 1870 PRO 1871 0.0338

PRO 1871 ALA 1872 0.0185

ALA 1872 GLN 1873 0.0177

GLN 1873 MET 1874 0.0278

MET 1874 GLU 1875 0.0045

GLU 1875 PRO 1876 0.0166

PRO 1876 PHE 1877 0.0341

PHE 1877 HIS 1878 0.0004

HIS 1878 GLN 1879 0.0306

GLN 1879 PRO 1880 0.0067

PRO 1880 GLY 1881 0.0337

GLY 1881 LYS 1882 0.0001

LYS 1882 LEU 1883 0.0237

LEU 1883 LEU 1884 0.0088

LEU 1884 GLN 1885 -0.2065

GLN 1885 MET 1886 0.0740

MET 1886 GLY 1887 0.0740

GLY 1887 ILE 1888 0.0862

ILE 1888 LYS 1889 0.0959

LYS 1889 THR 1890 0.0293

THR 1890 PRO 1891 0.0312

PRO 1891 GLY 1892 0.0879

GLY 1892 LEU 1893 0.0296

LEU 1893 ILE 1894 0.0989

ILE 1894 ASP 1895 0.0307

ASP 1895 THR 1896 0.1001

THR 1896 LEU 1897 0.1052

LEU 1897 GLN 1898 0.0261

GLN 1898 PHE 1899 0.0806

PHE 1899 SER 1900 0.0955

SER 1900 LYS 1901 -0.0373

LYS 1901 THR 1902 0.1130

THR 1902 ASP 1903 0.1049

ASP 1903 ALA 1904 0.1276

ALA 1904 THR 1905 0.1222

THR 1905 ASP 1906 0.0926

ASP 1906 ASN 1907 0.0699

ASN 1907 LEU 1908 0.0815

LEU 1908 PRO 1909 0.0495

PRO 1909 ASN 1910 0.1273

ASN 1910 ASP 1911 0.0525

ASP 1911 TYR 1912 0.1134

TYR 1912 ILE 1913 0.1006

ILE 1913 GLU 1914 0.0826

GLU 1914 ILE 1915 0.1289

ILE 1915 GLU 1916 0.0872

GLU 1916 PRO 1917 -0.0305

PRO 1917 LYS 1918 0.1344

LYS 1918 ALA 1919 0.0311

ALA 1919 PHE 1920 0.0373

PHE 1920 GLY 1921 0.0203

GLY 1921 LEU 1922 0.1151

LEU 1922 ASN 1923 0.0125

ASN 1923 PHE 1924 0.0562

PHE 1924 ARG 1925 0.1447

ARG 1925 ASP 1926 0.0350

ASP 1926 VAL 1927 0.1282

VAL 1927 MET 1928 0.0477

MET 1928 VAL 1929 0.1036

VAL 1929 ALA 1930 0.0989

ALA 1930 MET 1931 0.0489

MET 1931 GLY 1932 0.1283

GLY 1932 GLN 1933 0.1890

GLN 1933 LEU 1934 0.1383

LEU 1934 GLU 1935 0.1398

GLU 1935 GLU 1936 0.0560

GLU 1936 SER 1937 0.0377

SER 1937 ILE 1938 0.1168

ILE 1938 MET 1939 0.1228

MET 1939 GLY 1940 0.1104

GLY 1940 PHE 1941 0.1126

PHE 1941 GLU 1942 0.1057

GLU 1942 CYS 1943 0.0230

CYS 1943 ALA 1944 0.0958

ALA 1944 GLY 1945 0.0190

GLY 1945 VAL 1946 0.0736

VAL 1946 VAL 1947 0.1403

VAL 1947 ARG 1948 0.0676

ARG 1948 ARG 1949 0.0880

ARG 1949 VAL 1950 0.0849

VAL 1950 GLY 1951 0.1326

GLY 1951 PRO 1952 0.1510

PRO 1952 SER 1953 0.0147

SER 1953 SER 1954 0.1521

SER 1954 ALA 1955 0.0776

ALA 1955 GLY 1956 0.0937

GLY 1956 HIS 1957 0.1085

HIS 1957 ASN 1958 0.1036

ASN 1958 ILE 1959 0.1328

ILE 1959 LYS 1960 0.0009

LYS 1960 VAL 1961 0.0877

VAL 1961 GLY 1962 0.1479

GLY 1962 ASP 1963 0.0268

ASP 1963 ARG 1964 0.1314

ARG 1964 VAL 1965 0.1551

VAL 1965 CYS 1966 0.0579

CYS 1966 ALA 1967 0.1002

ALA 1967 LEU 1968 0.0483

LEU 1968 LEU 1969 0.1176

LEU 1969 GLY 1970 0.1110

GLY 1970 GLY 1971 0.1245

GLY 1971 GLN 1972 0.0149

GLN 1972 TRP 1973 0.0905

TRP 1973 THR 1974 0.0347

THR 1974 ASN 1975 0.0287

ASN 1975 THR 1976 0.1259

THR 1976 VAL 1977 0.0235

VAL 1977 ARG 1978 0.1163

ARG 1978 VAL 1979 0.0403

VAL 1979 HIS 1980 0.1001

HIS 1980 TRP 1981 0.1247

TRP 1981 HIS 1982 0.0123

HIS 1982 SER 1983 0.1326

SER 1983 VAL 1984 0.0594

VAL 1984 ALA 1985 0.1332

ALA 1985 PRO 1986 0.0599

PRO 1986 ILE 1987 0.1329

ILE 1987 PRO 1988 0.1262

PRO 1988 GLN 1989 0.0101

GLN 1989 ALA 1990 0.1267

ALA 1990 MET 1991 0.0913

MET 1991 ASP 1992 0.1166

ASP 1992 TRP 1993 0.1320

TRP 1993 GLU 1994 0.0840

GLU 1994 THR 1995 0.0798

THR 1995 ALA 1996 0.1314

ALA 1996 ALA 1997 0.2122

ALA 1997 SER 1998 0.0560

SER 1998 ILE 1999 0.0921

ILE 1999 PRO 2000 0.1179

PRO 2000 ILE 2001 0.0713

ILE 2001 VAL 2002 0.1017

VAL 2002 PHE 2003 0.1206

PHE 2003 VAL 2004 0.1172

VAL 2004 THR 2005 0.0710

THR 2005 ALA 2006 0.1064

ALA 2006 TYR 2007 0.1223

TYR 2007 ILE 2008 0.1032

ILE 2008 SER 2009 0.0689

SER 2009 LEU 2010 0.1155

LEU 2010 VAL 2011 0.1158

VAL 2011 LYS 2012 0.1216

LYS 2012 ILE 2013 0.3466

ILE 2013 ALA 2014 0.0631

ALA 2014 ARG 2015 0.0833

ARG 2015 MET 2016 0.0974

MET 2016 GLN 2017 0.1094

GLN 2017 ALA 2018 0.1091

ALA 2018 GLY 2019 0.0198

GLY 2019 GLU 2020 0.0979

GLU 2020 THR 2021 0.0921

THR 2021 VAL 2022 0.0961

VAL 2022 LEU 2023 0.0984

LEU 2023 ILE 2024 0.0559

ILE 2024 HIS 2025 0.1042

HIS 2025 ALA 2026 0.0808

ALA 2026 ALA 2027 0.0945

ALA 2027 SER 2028 0.0830

SER 2028 GLY 2029 -0.1413

GLY 2029 GLY 2030 0.0861

GLY 2030 VAL 2031 0.0827

VAL 2031 GLY 2032 0.0743

GLY 2032 GLN 2033 0.0882

GLN 2033 ALA 2034 0.1240

ALA 2034 ALA 2035 0.0117

ALA 2035 ILE 2036 0.1321

ILE 2036 ILE 2037 0.0568

ILE 2037 LEU 2038 0.1262

LEU 2038 ALA 2039 0.0144

ALA 2039 LYS 2040 0.1264

LYS 2040 HIS 2041 0.0962

HIS 2041 VAL 2042 0.0549

VAL 2042 GLY 2043 0.0985

GLY 2043 ALA 2044 0.0883

ALA 2044 GLU 2045 0.0370

GLU 2045 ILE 2046 0.1539

ILE 2046 PHE 2047 0.1236

PHE 2047 ALA 2048 0.1252

ALA 2048 THR 2049 0.1605

THR 2049 VAL 2050 0.1172

VAL 2050 GLY 2051 0.1624

GLY 2051 THR 2052 0.1579

THR 2052 ASP 2053 0.1618

ASP 2053 GLU 2054 0.0035

GLU 2054 LYS 2055 0.1624

LYS 2055 ARG 2056 0.0768

ARG 2056 ASP 2057 0.1227

ASP 2057 LEU 2058 0.0732

LEU 2058 LEU 2059 0.1180

LEU 2059 ILE 2060 0.1428

ILE 2060 LYS 2061 0.1055

LYS 2061 GLU 2062 0.0985

GLU 2062 TYR 2063 0.1255

TYR 2063 LYS 2064 0.0965

LYS 2064 ILE 2065 0.0791

ILE 2065 PRO 2066 0.0517

PRO 2066 ASP 2067 0.1452

ASP 2067 ASP 2068 0.0484

ASP 2068 HIS 2069 0.1266

HIS 2069 ILE 2070 0.1471

ILE 2070 PHE 2071 0.1234

PHE 2071 SER 2072 0.1644

SER 2072 SER 2073 0.1439

SER 2073 ARG 2074 0.1398

ARG 2074 ASN 2075 0.0184

ASN 2075 ALA 2076 0.1260

ALA 2076 LEU 2077 0.3093

LEU 2077 PHE 2078 0.0427

PHE 2078 ALA 2079 0.1064

ALA 2079 LYS 2080 0.0297

LYS 2080 SER 2081 0.0959

SER 2081 ILE 2082 0.0584

ILE 2082 ARG 2083 0.0651

ARG 2083 GLN 2084 0.0836

GLN 2084 ARG 2085 0.0387

ARG 2085 THR 2086 0.1060

THR 2086 ASN 2087 0.0205

ASN 2087 GLY 2088 0.1101

GLY 2088 LYS 2089 0.0398

LYS 2089 GLY 2090 0.0848

GLY 2090 VAL 2091 0.0002

VAL 2091 ASP 2092 0.0730

ASP 2092 VAL 2093 0.0762

VAL 2093 VAL 2094 0.0891

VAL 2094 LEU 2095 0.0433

LEU 2095 ASN 2096 0.0748

ASN 2096 CYS 2097 0.0847

CYS 2097 LEU 2098 0.0169

LEU 2098 ALA 2099 0.0796

ALA 2099 GLY 2100 0.0170

GLY 2100 GLY 2101 0.0349

GLY 2101 LEU 2102 0.0663

LEU 2102 LEU 2103 0.0627

LEU 2103 GLN 2104 0.0313

GLN 2104 GLU 2105 0.0819

GLU 2105 SER 2106 0.0190

SER 2106 PHE 2107 0.0906

PHE 2107 ASP 2108 0.0148

ASP 2108 CYS 2109 -0.0732

CYS 2109 LEU 2110 0.0410

LEU 2110 ALA 2111 0.0547

ALA 2111 ASP 2112 0.0546

ASP 2112 PHE 2113 0.0175

PHE 2113 GLY 2114 0.0484

GLY 2114 ARG 2115 0.0229

ARG 2115 PHE 2116 0.0567

PHE 2116 ILE 2117 0.0125

ILE 2117 GLU 2118 0.0568

GLU 2118 ILE 2119 0.0183

ILE 2119 GLY 2120 0.0464

GLY 2120 LYS 2121 0.0557

LYS 2121 ARG 2122 0.0299

ARG 2122 ASP 2123 0.0197

ASP 2123 ILE 2124 0.0411

ILE 2124 GLU 2125 0.0408

GLU 2125 LEU 2126 0.0032

LEU 2126 ASN 2127 0.0379

ASN 2127 HIS 2128 0.0303

HIS 2128 CYS 2129 0.0389

CYS 2129 LEU 2130 0.0258

LEU 2130 ASN 2131 0.0363

ASN 2131 MET 2132 0.0282

MET 2132 GLY 2133 0.0382

GLY 2133 MET 2134 0.0136

MET 2134 PHE 2135 0.0252

PHE 2135 ALA 2136 0.0364

ALA 2136 ARG 2137 0.0272

ARG 2137 SER 2138 0.0161

SER 2138 ALA 2139 0.0387

ALA 2139 THR 2140 0.0306

THR 2140 PHE 2141 0.0658

PHE 2141 THR 2142 0.0117

THR 2142 ALA 2143 0.0629

ALA 2143 VAL 2144 0.0209

VAL 2144 ASP 2145 0.0467

ASP 2145 LEU 2146 0.0306

LEU 2146 ILE 2147 0.0954

ILE 2147 ALA 2148 0.0754

ALA 2148 ILE 2149 0.1190

ILE 2149 GLY 2150 0.0006

GLY 2150 ARG 2151 0.1197

ARG 2151 ASP 2152 0.0660

ASP 2152 ARG 2153 0.1188

ARG 2153 SER 2154 0.0291

SER 2154 TYR 2155 0.1178

TYR 2155 MET 2156 0.0776

MET 2156 PHE 2157 0.3442

PHE 2157 ALA 2158 0.1006

ALA 2158 GLU 2159 0.0799

GLU 2159 ALA 2160 0.1361

ALA 2160 LEU 2161 0.0385

LEU 2161 PRO 2162 0.1092

PRO 2162 LYS 2163 0.0634

LYS 2163 ILE 2164 0.1426

ILE 2164 MET 2165 0.0064

MET 2165 THR 2166 0.1409

THR 2166 LEU 2167 0.0722

LEU 2167 LEU 2168 0.0993

LEU 2168 GLN 2169 0.0629

GLN 2169 GLU 2170 0.0993

GLU 2170 LYS 2171 0.1304

LYS 2171 ALA 2172 0.0217

ALA 2172 ILE 2173 0.0756

ILE 2173 ARG 2174 0.0777

ARG 2174 PRO 2175 0.1159

PRO 2175 VAL 2176 0.1164

VAL 2176 THR 2177 0.1114

THR 2177 PRO 2178 0.0893

PRO 2178 ILE 2179 0.0967

ILE 2179 SER 2180 0.1141

SER 2180 ILE 2181 0.0386

ILE 2181 TYR 2182 0.1158

TYR 2182 LYS 2183 0.0566

LYS 2183 ILE 2184 0.1255

ILE 2184 GLY 2185 0.0980

GLY 2185 ASP 2186 0.0785

ASP 2186 ILE 2187 0.0508

ILE 2187 GLU 2188 0.1141

GLU 2188 THR 2189 0.1147

THR 2189 ALA 2190 0.1108

ALA 2190 PHE 2191 0.0762

PHE 2191 ARG 2192 0.1277

ARG 2192 LEU 2193 0.1320

LEU 2193 MET 2194 0.0829

MET 2194 GLN 2195 0.1028

GLN 2195 ALA 2196 0.1313

ALA 2196 GLY 2197 0.1145

GLY 2197 LYS 2198 0.0919

LYS 2198 HIS 2199 0.1087

HIS 2199 MET 2200 0.1271

MET 2200 GLY 2201 0.1294

GLY 2201 LYS 2202 0.0973

LYS 2202 ILE 2203 0.0773

ILE 2203 VAL 2204 0.0600

VAL 2204 ILE 2205 -0.0416

ILE 2205 THR 2206 0.0030

THR 2206 ALA 2207 0.0482

ALA 2207 PRO 2208 0.0069

PRO 2208 GLU 2209 0.0391

GLU 2209 ASP 2210 0.0524

ASP 2210 ALA 2211 0.0007

ALA 2211 MET 2212 0.0395

MET 2212 VAL 2213 0.0055

VAL 2213 PRO 2214 0.0285

PRO 2214 VAL 2215 0.0532

VAL 2215 ILE 2216 0.0329

ILE 2216 THR 2217 0.0466

THR 2217 ARG 2218 0.0261

ARG 2218 PRO 2219 0.0527

PRO 2219 PRO 2220 0.0503

PRO 2220 LYS 2221 0.9006

LYS 2221 LEU 2222 0.0053

LEU 2222 GLN 2223 0.0377

GLN 2223 LEU 2224 0.0078

LEU 2224 ARG 2225 0.0341

ARG 2225 PRO 2226 0.0378

PRO 2226 ASP 2227 0.0159

ASP 2227 ALA 2228 0.0236

ALA 2228 SER 2229 0.0288

SER 2229 TYR 2230 0.0379

TYR 2230 LEU 2231 0.0149

LEU 2231 ILE 2232 0.0373

ILE 2232 VAL 2233 0.0143

VAL 2233 GLY 2234 0.0358

GLY 2234 GLY 2235 0.0161

GLY 2235 LEU 2236 0.0380

LEU 2236 GLY 2237 0.0208

GLY 2237 GLY 2238 0.0024

GLY 2238 ILE 2239 0.0328

ILE 2239 GLY 2240 0.0190

GLY 2240 ARG 2241 0.0197

ARG 2241 SER 2242 0.0164

SER 2242 LEU 2243 0.0214

LEU 2243 CYS 2244 0.0313

CYS 2244 LYS 2245 0.0026

LYS 2245 ASN 2246 0.0318

ASN 2246 PHE 2247 0.0127

PHE 2247 VAL 2248 0.0309

VAL 2248 GLU 2249 0.0036

GLU 2249 ASN 2250 0.0290

ASN 2250 GLY 2251 0.0237

GLY 2251 ALA 2252 0.0089

ALA 2252 ARG 2253 0.1120

ARG 2253 SER 2254 0.0056

SER 2254 LEU 2255 0.0334

LEU 2255 VAL 2256 0.0082

VAL 2256 LEU 2257 0.0343

LEU 2257 LEU 2258 0.0127

LEU 2258 SER 2259 0.0339

SER 2259 ARG 2260 0.0143

ARG 2260 ASN 2261 0.0310

ASN 2261 ALA 2262 0.0299

ALA 2262 ASN 2263 0.0333

ASN 2263 VAL 2264 0.0119

VAL 2264 SER 2265 0.0281

SER 2265 GLN 2266 0.0279

GLN 2266 GLN 2267 0.0234

GLN 2267 SER 2268 0.0337

SER 2268 GLY 2269 0.0560

GLY 2269 GLU 2270 0.0020

GLU 2270 PHE 2271 0.0357

PHE 2271 LEU 2272 0.0119

LEU 2272 ASP 2273 0.0317

ASP 2273 GLU 2274 0.0090

GLU 2274 LEU 2275 0.0280

LEU 2275 ARG 2276 0.0248

ARG 2276 SER 2277 0.0126

SER 2277 THR 2278 0.0328

THR 2278 GLY 2279 0.0110

GLY 2279 CYS 2280 0.0297

CYS 2280 ILE 2281 0.0007

ILE 2281 VAL 2282 0.0354

VAL 2282 GLY 2283 0.0051

GLY 2283 VAL 2284 0.0354

VAL 2284 VAL 2285 -0.1698

VAL 2285 ASP 2286 0.0295

ASP 2286 CYS 2287 0.0312

CYS 2287 ASP 2288 0.0334

ASP 2288 ILE 2289 0.0328

ILE 2289 SER 2290 0.0280

SER 2290 SER 2291 0.0085

SER 2291 LYS 2292 0.0284

LYS 2292 THR 2293 0.0225

THR 2293 GLN 2294 0.0136

GLN 2294 VAL 2295 0.0249

VAL 2295 GLU 2296 0.0140

GLU 2296 ALA 2297 0.0327

ALA 2297 THR 2298 0.0013

THR 2298 MET 2299 0.0335

MET 2299 LEU 2300 0.0130

LEU 2300 ARG 2301 0.0775

ARG 2301 LEU 2302 0.0066

LEU 2302 LYS 2303 0.0259

LYS 2303 LYS 2304 0.0272

LYS 2304 ASP 2305 0.0131

ASP 2305 MET 2306 0.0138

MET 2306 LEU 2307 0.0211

LEU 2307 PRO 2308 0.0226

PRO 2308 ILE 2309 0.0274

ILE 2309 ARG 2310 0.0181

ARG 2310 GLY 2311 0.0265

GLY 2311 ILE 2312 0.0230

ILE 2312 VAL 2313 0.0238

VAL 2313 HIS 2314 0.0141

HIS 2314 ALA 2315 0.0222

ALA 2315 GLY 2316 0.0084

GLY 2316 MET 2317 -0.2695

MET 2317 VAL 2318 0.0030

VAL 2318 LEU 2319 0.0055

LEU 2319 GLN 2320 0.0058

GLN 2320 ASP 2321 0.0069

ASP 2321 SER 2322 0.0070

SER 2322 VAL 2323 0.0065

VAL 2323 PHE 2324 0.0027

PHE 2324 GLU 2325 0.0054

GLU 2325 ARG 2326 0.0038

ARG 2326 MET 2327 0.0046

MET 2327 SER 2328 0.0071

SER 2328 LEU 2329 0.0020

LEU 2329 ASP 2330 0.0059

ASP 2330 ASP 2331 0.0071

ASP 2331 TYR 2332 0.0008

TYR 2332 ASN 2333 -0.2401

ASN 2333 THR 2334 0.0014

THR 2334 ALA 2335 0.0020

ALA 2335 ILE 2336 0.0028

ILE 2336 ARG 2337 0.0027

ARG 2337 PRO 2338 0.0000

PRO 2338 LYS 2339 0.0027

LYS 2339 VAL 2340 0.0014

VAL 2340 GLN 2341 0.0027

GLN 2341 GLY 2342 0.0006

GLY 2342 SER 2343 0.0020

SER 2343 TRP 2344 0.0020

TRP 2344 ASN 2345 0.0027

ASN 2345 LEU 2346 0.0001

LEU 2346 HIS 2347 0.0028

HIS 2347 SER 2348 0.0022

SER 2348 GLY 2349 0.1404

GLY 2349 LEU 2350 0.0070

LEU 2350 SER 2351 0.0164

SER 2351 ASP 2352 0.0186

ASP 2352 CYS 2353 0.0020

CYS 2353 ASP 2354 0.0083

ASP 2354 LEU 2355 0.0104

LEU 2355 ASP 2356 0.0008

ASP 2356 PHE 2357 0.0185

PHE 2357 PHE 2358 0.0131

PHE 2358 ILE 2359 0.0131

ILE 2359 MET 2360 0.0165

MET 2360 LEU 2361 0.0121

LEU 2361 SER 2362 0.0171

SER 2362 SER 2363 0.0142

SER 2363 LEU 2364 0.0116

LEU 2364 ALA 2365 0.1076

ALA 2365 GLY 2366 0.0019

GLY 2366 VAL 2367 0.0075

VAL 2367 SER 2368 0.0002

SER 2368 GLY 2369 0.0070

GLY 2369 SER 2370 0.0032

SER 2370 ALA 2371 0.0038

ALA 2371 SER 2372 0.0072

SER 2372 GLN 2373 0.0013

GLN 2373 ALA 2374 0.0049

ALA 2374 ASN 2375 0.0048

ASN 2375 TYR 2376 0.0074

TYR 2376 THR 2377 0.0073

THR 2377 ALA 2378 0.0033

ALA 2378 GLY 2379 0.0064

GLY 2379 GLY 2380 0.0075

GLY 2380 ALA 2381 -0.0148

ALA 2381 TYR 2382 0.0035

TYR 2382 GLN 2383 0.0014

GLN 2383 ASP 2384 0.0029

ASP 2384 ALA 2385 0.0027

ALA 2385 LEU 2386 0.0040

LEU 2386 ALA 2387 -0.0001

ALA 2387 LYS 2388 0.0039

LYS 2388 TYR 2389 0.0024

TYR 2389 ARG 2390 0.0026

ARG 2390 ARG 2391 0.0013

ARG 2391 ALA 2392 0.0030

ALA 2392 GLN 2393 0.0038

GLN 2393 GLY 2394 0.0004

GLY 2394 LEU 2395 0.0040

LEU 2395 SER 2396 0.0026

SER 2396 ALA 2397 0.0241

ALA 2397 VAL 2398 0.0065

VAL 2398 SER 2399 0.0025

SER 2399 ILE 2400 0.0060

ILE 2400 ASP 2401 0.0021

ASP 2401 LEU 2402 0.0055

LEU 2402 GLY 2403 0.0059

GLY 2403 MET 2404 0.0065

MET 2404 VAL 2405 0.0024

VAL 2405 GLN 2406 0.0062

GLN 2406 SER 2407 0.0040

SER 2407 VAL 2408 0.0061

VAL 2408 GLY 2409 0.0018

GLY 2409 TYR 2410 0.0001

TYR 2410 VAL 2411 0.0064

VAL 2411 ALA 2412 0.0031

ALA 2412 GLU 2413 -0.0114

GLU 2413 THR 2414 0.0004

THR 2414 LYS 2415 0.0083

LYS 2415 GLY 2416 0.0028

GLY 2416 VAL 2417 0.0109

VAL 2417 ALA 2418 0.0095

ALA 2418 GLU 2419 0.0046

GLU 2419 ARG 2420 0.0059

ARG 2420 LEU 2421 0.0089

LEU 2421 VAL 2422 0.0107

VAL 2422 ARG 2423 0.0007

ARG 2423 MET 2424 0.0104

MET 2424 GLY 2425 0.0091

GLY 2425 TYR 2426 0.0015

TYR 2426 SER 2427 0.0044

SER 2427 PRO 2428 0.0032

PRO 2428 ILE 2429 0.0051

ILE 2429 SER 2430 0.0051

SER 2430 GLU 2431 0.0159

GLU 2431 MET 2432 0.0107

MET 2432 GLU 2433 0.0116

GLU 2433 VAL 2434 0.0177

VAL 2434 LEU 2435 0.0036

LEU 2435 LYS 2436 0.0198

LYS 2436 ILE 2437 0.0057

ILE 2437 VAL 2438 0.0198

VAL 2438 GLU 2439 0.0025

GLU 2439 HIS 2440 0.0183

HIS 2440 ALA 2441 0.0120

ALA 2441 ILE 2442 0.0080

ILE 2442 THR 2443 0.0128

THR 2443 ASN 2444 0.0118

ASN 2444 PRO 2445 -0.1985

PRO 2445 PRO 2446 0.0053

PRO 2446 PRO 2447 0.0055

PRO 2447 GLU 2448 0.0026

GLU 2448 ALA 2449 0.0020

ALA 2449 SER 2450 0.0054

SER 2450 SER 2451 0.0017

SER 2451 ALA 2452 0.0045

ALA 2452 GLN 2453 0.0057

GLN 2453 ILE 2454 0.0013

ILE 2454 ILE 2455 0.0059

ILE 2455 THR 2456 0.0030

THR 2456 GLY 2457 0.0052

GLY 2457 ILE 2458 0.0056

ILE 2458 SER 2459 0.0021

SER 2459 THR 2460 0.0044

THR 2460 LYS 2461 0.1274

LYS 2461 PRO 2462 0.0217

PRO 2462 GLY 2463 0.0294

GLY 2463 ARG 2464 0.0277

ARG 2464 HIS 2465 0.0032

HIS 2465 TRP 2466 0.0303

TRP 2466 THR 2467 0.0296

THR 2467 GLU 2468 0.0237

GLU 2468 SER 2469 0.0102

SER 2469 SER 2470 0.0157

SER 2470 TRP 2471 0.0219

TRP 2471 LEU 2472 0.0120

LEU 2472 GLN 2473 0.0303

GLN 2473 ASP 2474 0.0072

ASP 2474 ALA 2475 0.0304

ALA 2475 ARG 2476 0.0270

ARG 2476 PHE 2477 0.0043

PHE 2477 ALA 2478 0.0381

ALA 2478 THR 2479 0.0413

THR 2479 LEU 2480 0.0330

LEU 2480 ARG 2481 0.0360

ARG 2481 GLU 2482 0.0367

GLU 2482 ARG 2483 0.0405

ARG 2483 ALA 2484 0.0359

ALA 2484 ARG 2485 0.0373

ARG 2485 ASP 2486 0.0405

ASP 2486 VAL 2487 0.0366

VAL 2487 LYS 2488 0.0364

LYS 2488 GLU 2489 0.0404

GLU 2489 LEU 2490 0.0413

LEU 2490 SER 2491 0.0281

SER 2491 ASN 2492 0.0367

ASN 2492 SER 2493 0.0993

SER 2493 GLN 2494 0.1154

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** sdgklnrdh ***

CA strain for 22101813491974862

--- normal mode 30 ---

Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *