Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *

CA strain for 22101813491974862

--- normal mode 22 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
ASN 989 LYS 990 0.1080

LYS 990 ALA 991 0.0795

ALA 991 HIS 992 0.0546

HIS 992 ARG 993 0.1142

ARG 993 GLN 994 0.1128

GLN 994 ARG 995 0.0517

ARG 995 VAL 996 0.0960

VAL 996 HIS 997 0.0311

HIS 997 PRO 998 0.0660

PRO 998 PRO 999 0.0992

PRO 999 HIS 1000 0.0878

HIS 1000 ASP 1001 0.0206

ASP 1001 LEU 1002 0.1105

LEU 1002 LEU 1003 0.0011

LEU 1003 GLY 1004 0.1086

GLY 1004 SER 1005 0.1253

SER 1005 LEU 1006 0.0289

LEU 1006 ILE 1007 0.0682

ILE 1007 VAL 1008 0.0307

VAL 1008 GLY 1009 0.0241

GLY 1009 ARG 1010 0.0877

ARG 1010 ASP 1011 0.0785

ASP 1011 LEU 1012 0.0723

LEU 1012 ARG 1013 0.0928

ARG 1013 GLU 1014 0.0628

GLU 1014 PRO 1015 0.0664

PRO 1015 THR 1016 0.0538

THR 1016 TRP 1017 0.0423

TRP 1017 ARG 1018 0.0793

ARG 1018 HIS 1019 0.0076

HIS 1019 PHE 1020 0.0682

PHE 1020 ILE 1021 -0.1230

ILE 1021 ARG 1022 0.0868

ARG 1022 VAL 1023 0.0091

VAL 1023 GLN 1024 0.0891

GLN 1024 ASP 1025 0.0778

ASP 1025 ILE 1026 0.0473

ILE 1026 PRO 1027 0.0289

PRO 1027 TRP 1028 0.0594

TRP 1028 ILE 1029 0.0838

ILE 1029 ARG 1030 0.0660

ARG 1030 ASP 1031 0.0358

ASP 1031 HIS 1032 0.0878

HIS 1032 VAL 1033 0.0921

VAL 1033 VAL 1034 0.0936

VAL 1034 GLN 1035 0.0896

GLN 1035 SER 1036 0.0919

SER 1036 ALA 1037 -0.1614

ALA 1037 LEU 1038 0.0739

LEU 1038 VAL 1039 0.0775

VAL 1039 TYR 1040 0.0574

TYR 1040 PRO 1041 0.0763

PRO 1041 GLY 1042 0.0794

GLY 1042 ALA 1043 0.0920

ALA 1043 GLY 1044 0.0565

GLY 1044 PHE 1045 0.0471

PHE 1045 ILE 1046 0.0918

ILE 1046 CYS 1047 0.0921

CYS 1047 MET 1048 0.0335

MET 1048 ALA 1049 0.0749

ALA 1049 MET 1050 0.0881

MET 1050 GLU 1051 0.0827

GLU 1051 ALA 1052 0.0320

ALA 1052 MET 1053 -0.0066

MET 1053 VAL 1054 0.0866

VAL 1054 GLN 1055 0.0644

GLN 1055 LEU 1056 0.0435

LEU 1056 HIS 1057 0.0919

HIS 1057 GLU 1058 0.0919

GLU 1058 LEU 1059 0.0390

LEU 1059 ARG 1060 0.0672

ARG 1060 ASP 1061 0.0891

ASP 1061 SER 1062 0.0852

SER 1062 GLN 1063 0.0885

GLN 1063 SER 1064 0.0051

SER 1064 ARG 1065 0.0867

ARG 1065 LYS 1066 0.0014

LYS 1066 VAL 1067 0.0731

VAL 1067 ALA 1068 0.0589

ALA 1068 GLY 1069 0.1041

GLY 1069 TYR 1070 0.0872

TYR 1070 ARG 1071 0.0884

ARG 1071 LEU 1072 0.0874

LEU 1072 ALA 1073 0.0887

ALA 1073 GLU 1074 0.0877

GLU 1074 VAL 1075 0.0756

VAL 1075 ASP 1076 0.0852

ASP 1076 ILE 1077 0.0681

ILE 1077 LEU 1078 0.0801

LEU 1078 ARG 1079 0.0752

ARG 1079 ALA 1080 0.0592

ALA 1080 MET 1081 0.0703

MET 1081 LEU 1082 0.0681

LEU 1082 ILE 1083 0.0883

ILE 1083 PRO 1084 0.0885

PRO 1084 ASP 1085 0.1315

ASP 1085 THR 1086 0.0387

THR 1086 SER 1087 0.0509

SER 1087 GLU 1088 0.0359

GLU 1088 GLY 1089 0.0670

GLY 1089 LEU 1090 0.0687

LEU 1090 GLU 1091 0.0104

GLU 1091 ALA 1092 0.0807

ALA 1092 HIS 1093 0.0338

HIS 1093 ILE 1094 0.0804

ILE 1094 SER 1095 0.0244

SER 1095 LEU 1096 0.0758

LEU 1096 ARG 1097 0.0458

ARG 1097 PRO 1098 0.0719

PRO 1098 CYS 1099 0.0725

CYS 1099 SER 1100 0.0323

SER 1100 THR 1101 0.0892

THR 1101 LYS 1102 0.0624

LYS 1102 LEU 1103 0.0128

LEU 1103 LEU 1104 0.0651

LEU 1104 LEU 1105 0.0565

LEU 1105 THR 1106 0.0528

THR 1106 ASN 1107 0.0615

ASN 1107 GLU 1108 0.0619

GLU 1108 TRP 1109 0.0242

TRP 1109 TYR 1110 0.0638

TYR 1110 ASP 1111 0.0491

ASP 1111 PHE 1112 0.0445

PHE 1112 CYS 1113 0.0547

CYS 1113 VAL 1114 0.0377

VAL 1114 SER 1115 0.0650

SER 1115 SER 1116 0.0583

SER 1116 VAL 1117 0.1348

VAL 1117 GLY 1118 0.0592

GLY 1118 ASP 1119 0.0825

ASP 1119 ASP 1120 0.0442

ASP 1120 ASP 1121 0.0545

ASP 1121 LYS 1122 0.0814

LYS 1122 PHE 1123 0.0816

PHE 1123 VAL 1124 0.0300

VAL 1124 ASP 1125 0.0827

ASP 1125 HIS 1126 0.0224

HIS 1126 CYS 1127 0.0786

CYS 1127 ARG 1128 0.0377

ARG 1128 GLY 1129 0.0805

GLY 1129 ARG 1130 0.0575

ARG 1130 ILE 1131 0.0827

ILE 1131 THR 1132 0.0654

THR 1132 ILE 1133 0.2135

ILE 1133 GLU 1134 0.0482

GLU 1134 PHE 1135 0.0482

PHE 1135 ASP 1136 0.0434

ASP 1136 THR 1137 0.0326

THR 1137 SER 1138 0.0510

SER 1138 GLY 1139 0.0510

GLY 1139 SER 1140 0.0372

SER 1140 ALA 1141 0.0127

ALA 1141 ASP 1142 0.0234

ASP 1142 THR 1143 0.0507

THR 1143 PRO 1144 0.0005

PRO 1144 ARG 1145 0.0475

ARG 1145 THR 1146 0.0233

THR 1146 SER 1147 0.0120

SER 1147 LEU 1148 0.0367

LEU 1148 ARG 1149 -0.1163

ARG 1149 GLU 1150 0.1194

GLU 1150 ARG 1151 0.0786

ARG 1151 SER 1152 0.1192

SER 1152 ARG 1153 0.0225

ARG 1153 SER 1154 0.1212

SER 1154 THR 1155 0.0911

THR 1155 GLY 1156 0.0912

GLY 1156 LEU 1157 0.1241

LEU 1157 MET 1158 0.0522

MET 1158 ARG 1159 0.0939

ARG 1159 SER 1160 0.1042

SER 1160 VAL 1161 0.0142

VAL 1161 ASP 1162 0.0874

ASP 1162 PRO 1163 0.0441

PRO 1163 SER 1164 0.0934

SER 1164 ASN 1165 0.0259

ASN 1165 LEU 1166 0.0351

LEU 1166 TYR 1167 0.0595

TYR 1167 SER 1168 0.0779

SER 1168 PHE 1169 0.0895

PHE 1169 LEU 1170 0.0122

LEU 1170 ARG 1171 0.0882

ARG 1171 ALA 1172 0.0802

ALA 1172 GLN 1173 0.0580

GLN 1173 GLY 1174 0.0411

GLY 1174 ILE 1175 0.0909

ILE 1175 TYR 1176 0.0887

TYR 1176 HIS 1177 0.0898

HIS 1177 GLY 1178 0.0907

GLY 1178 PRO 1179 0.0669

PRO 1179 ILE 1180 0.0552

ILE 1180 PHE 1181 0.1021

PHE 1181 GLN 1182 0.0023

GLN 1182 ASN 1183 0.0862

ASN 1183 LEU 1184 0.0432

LEU 1184 LYS 1185 0.0193

LYS 1185 THR 1186 0.0586

THR 1186 ILE 1187 0.0906

ILE 1187 SER 1188 0.0571

SER 1188 SER 1189 0.0866

SER 1189 ARG 1190 0.0828

ARG 1190 LYS 1191 0.0786

LYS 1191 ASP 1192 0.0440

ASP 1192 HIS 1193 0.0905

HIS 1193 SER 1194 0.0903

SER 1194 GLU 1195 0.0905

GLU 1195 SER 1196 0.0748

SER 1196 SER 1197 0.2016

SER 1197 PHE 1198 0.0585

PHE 1198 VAL 1199 0.0783

VAL 1199 VAL 1200 0.0117

VAL 1200 ALA 1201 0.0886

ALA 1201 ASN 1202 0.0809

ASN 1202 THR 1203 0.0359

THR 1203 ALA 1204 0.0710

ALA 1204 SER 1205 0.0429

SER 1205 VAL 1206 0.0811

VAL 1206 MET 1207 0.0053

MET 1207 PRO 1208 0.0706

PRO 1208 ASN 1209 0.0879

ASN 1209 GLY 1210 0.0675

GLY 1210 PHE 1211 0.0211

PHE 1211 GLN 1212 0.0882

GLN 1212 SER 1213 0.1187

SER 1213 PRO 1214 0.0873

PRO 1214 HIS 1215 0.0873

HIS 1215 VAL 1216 0.0854

VAL 1216 ILE 1217 0.0418

ILE 1217 HIS 1218 0.0862

HIS 1218 PRO 1219 0.0909

PRO 1219 THR 1220 0.0116

THR 1220 THR 1221 0.0857

THR 1221 LEU 1222 0.0747

LEU 1222 ASP 1223 0.0797

ASP 1223 SER 1224 0.0171

SER 1224 ILE 1225 0.0896

ILE 1225 PHE 1226 0.0859

PHE 1226 GLN 1227 0.0307

GLN 1227 GLY 1228 0.0713

GLY 1228 ALA 1229 0.1480

ALA 1229 TYR 1230 0.0656

TYR 1230 THR 1231 0.0261

THR 1231 ALA 1232 0.0831

ALA 1232 LEU 1233 0.0838

LEU 1233 PRO 1234 0.0210

PRO 1234 GLY 1235 0.0723

GLY 1235 ALA 1236 0.0478

ALA 1236 GLY 1237 0.0466

GLY 1237 LEU 1238 0.0656

LEU 1238 ASP 1239 0.0831

ASP 1239 GLN 1240 0.0042

GLN 1240 ASN 1241 0.0727

ASN 1241 THR 1242 0.0114

THR 1242 ALA 1243 0.0578

ALA 1243 MET 1244 0.0776

MET 1244 ILE 1245 -0.2521

ILE 1245 PRO 1246 0.0581

PRO 1246 ARG 1247 0.0592

ARG 1247 SER 1248 0.0755

SER 1248 ILE 1249 0.0925

ILE 1249 GLN 1250 0.0841

GLN 1250 GLU 1251 0.0895

GLU 1251 LEU 1252 0.0913

LEU 1252 TYR 1253 0.0892

TYR 1253 LEU 1254 0.0924

LEU 1254 SER 1255 0.0921

SER 1255 SER 1256 0.0678

SER 1256 ALA 1257 0.0361

ALA 1257 LEU 1258 0.0720

LEU 1258 THR 1259 0.0919

THR 1259 SER 1260 0.0927

SER 1260 ASP 1261 0.0912

ASP 1261 VAL 1262 0.0614

VAL 1262 GLY 1263 0.0106

GLY 1263 GLN 1264 0.0814

GLN 1264 CYS 1265 0.0553

CYS 1265 LEU 1266 0.0679

LEU 1266 VAL 1267 0.0639

VAL 1267 SER 1268 0.0704

SER 1268 ASP 1269 0.0766

ASP 1269 THR 1270 0.0762

THR 1270 SER 1271 0.0825

SER 1271 LEU 1272 0.0814

LEU 1272 ILE 1273 0.0477

ILE 1273 ARG 1274 0.0826

ARG 1274 TYR 1275 0.0725

TYR 1275 ASP 1276 0.0811

ASP 1276 GLY 1277 0.0590

GLY 1277 GLN 1278 0.0100

GLN 1278 SER 1279 0.0700

SER 1279 PHE 1280 0.0804

PHE 1280 THR 1281 0.0664

THR 1281 VAL 1282 0.0814

VAL 1282 ASN 1283 0.0760

ASN 1283 VAL 1284 0.0847

VAL 1284 ASP 1285 0.0845

ASP 1285 VAL 1286 0.0843

VAL 1286 SER 1287 0.0830

SER 1287 SER 1288 0.0845

SER 1288 LYS 1289 0.0085

LYS 1289 ALA 1290 0.0792

ALA 1290 ASP 1291 0.0767

ASP 1291 SER 1292 0.0441

SER 1292 GLU 1293 0.0432

GLU 1293 HIS 1294 0.0854

HIS 1294 THR 1295 0.0105

THR 1295 PRO 1296 0.0779

PRO 1296 VAL 1297 0.0471

VAL 1297 LEU 1298 0.0853

LEU 1298 GLU 1299 0.0830

GLU 1299 ILE 1300 0.0853

ILE 1300 LYS 1301 0.0850

LYS 1301 GLY 1302 0.0825

GLY 1302 LEU 1303 0.0851

LEU 1303 ARG 1304 0.0838

ARG 1304 ASN 1305 0.0732

ASN 1305 GLN 1306 0.0856

GLN 1306 SER 1307 0.0692

SER 1307 VAL 1308 0.0646

VAL 1308 GLY 1309 0.0386

GLY 1309 GLN 1310 0.0084

GLN 1310 MET 1311 0.0269

MET 1311 ALA 1312 0.0068

ALA 1312 PRO 1313 0.0191

PRO 1313 GLN 1314 0.0269

GLN 1314 PRO 1315 0.0071

PRO 1315 GLY 1316 0.0229

GLY 1316 ASP 1317 0.0215

ASP 1317 SER 1318 0.0168

SER 1318 SER 1319 0.0265

SER 1319 ASN 1320 0.0061

ASN 1320 ASN 1321 0.0208

ASN 1321 ASP 1322 0.0097

ASP 1322 LEU 1323 0.0264

LEU 1323 CYS 1324 0.0017

CYS 1324 PHE 1325 -0.3442

PHE 1325 LYS 1326 0.0019

LYS 1326 LEU 1327 0.0012

LEU 1327 ASP 1328 0.0031

ASP 1328 TRP 1329 0.0015

TRP 1329 ALA 1330 0.0033

ALA 1330 PRO 1331 0.0020

PRO 1331 ASP 1332 0.0032

ASP 1332 ILE 1333 0.0028

ILE 1333 SER 1334 0.0018

SER 1334 SER 1335 0.0015

SER 1335 VAL 1336 0.0029

VAL 1336 LYS 1337 0.0027

LYS 1337 GLN 1338 0.0022

GLN 1338 GLU 1339 0.0031

GLU 1339 ARG 1340 0.0031

ARG 1340 LEU 1341 0.2198

LEU 1341 LYS 1342 0.0050

LYS 1342 GLU 1343 0.0323

GLU 1343 LYS 1344 0.0273

LYS 1344 PHE 1345 0.0230

PHE 1345 GLY 1346 0.0079

GLY 1346 PHE 1347 0.0158

PHE 1347 PRO 1348 0.0205

PRO 1348 LEU 1349 0.0022

LEU 1349 ASP 1350 0.0317

ASP 1350 PRO 1351 0.0073

PRO 1351 THR 1352 0.0326

THR 1352 GLU 1353 0.0336

GLU 1353 ALA 1354 0.0262

ALA 1354 ASP 1355 0.0131

ASP 1355 ILE 1356 0.0345

ILE 1356 ILE 1357 0.0462

ILE 1357 MET 1358 0.0190

MET 1358 GLY 1359 0.0656

GLY 1359 LEU 1360 0.0576

LEU 1360 ARG 1361 0.0769

ARG 1361 GLN 1362 0.0064

GLN 1362 ALA 1363 0.0810

ALA 1363 CYS 1364 0.0665

CYS 1364 ILE 1365 0.0396

ILE 1365 HIS 1366 0.0465

HIS 1366 PHE 1367 0.0645

PHE 1367 ILE 1368 0.0806

ILE 1368 HIS 1369 0.0088

HIS 1369 ARG 1370 0.0723

ARG 1370 SER 1371 0.0544

SER 1371 LEU 1372 0.0774

LEU 1372 GLN 1373 -0.0132

GLN 1373 SER 1374 0.0914

SER 1374 LEU 1375 0.0589

LEU 1375 THR 1376 0.0706

THR 1376 ALA 1377 0.0869

ALA 1377 PRO 1378 0.0790

PRO 1378 ASP 1379 0.0702

ASP 1379 ARG 1380 0.0799

ARG 1380 ASP 1381 0.0864

ASP 1381 GLN 1382 0.0713

GLN 1382 LEU 1383 0.0689

LEU 1383 ASP 1384 0.0020

ASP 1384 TRP 1385 0.0725

TRP 1385 HIS 1386 0.0878

HIS 1386 GLN 1387 0.0143

GLN 1387 LYS 1388 0.0843

LYS 1388 ARG 1389 0.0222

ARG 1389 PHE 1390 0.0757

PHE 1390 TYR 1391 0.0125

TYR 1391 ASP 1392 0.0819

ASP 1392 TRP 1393 0.0725

TRP 1393 MET 1394 0.0321

MET 1394 VAL 1395 0.0566

VAL 1395 LEU 1396 0.0606

LEU 1396 GLN 1397 0.0845

GLN 1397 ILE 1398 0.0005

ILE 1398 GLN 1399 0.0848

GLN 1399 LEU 1400 0.0561

LEU 1400 ALA 1401 0.0549

ALA 1401 GLU 1402 0.0341

GLU 1402 GLU 1403 0.0654

GLU 1403 ASP 1404 0.0820

ASP 1404 ARG 1405 -0.0501

ARG 1405 LEU 1406 0.0808

LEU 1406 ALA 1407 0.0847

ALA 1407 PRO 1408 0.0488

PRO 1408 ASN 1409 0.0220

ASN 1409 SER 1410 0.0776

SER 1410 SER 1411 0.0304

SER 1411 ALA 1412 0.0720

ALA 1412 TRP 1413 0.0590

TRP 1413 LEU 1414 0.0701

LEU 1414 GLN 1415 0.0259

GLN 1415 CYS 1416 0.0838

CYS 1416 SER 1417 0.0590

SER 1417 SER 1418 0.0818

SER 1418 SER 1419 0.0903

SER 1419 ASP 1420 0.0637

ASP 1420 GLU 1421 0.0576

GLU 1421 GLN 1422 0.0798

GLN 1422 LYS 1423 0.0767

LYS 1423 LEU 1424 0.0565

LEU 1424 LEU 1425 0.0677

LEU 1425 GLU 1426 0.0808

GLU 1426 ASN 1427 0.0707

ASN 1427 VAL 1428 0.0574

VAL 1428 ARG 1429 0.0754

ARG 1429 ALA 1430 0.0781

ALA 1430 SER 1431 0.0685

SER 1431 SER 1432 0.0373

SER 1432 VAL 1433 0.0665

VAL 1433 ASN 1434 0.0743

ASN 1434 GLY 1435 0.0113

GLY 1435 GLN 1436 0.0799

GLN 1436 MET 1437 0.0502

MET 1437 VAL 1438 0.0427

VAL 1438 VAL 1439 0.0409

VAL 1439 HIS 1440 0.0682

HIS 1440 VAL 1441 0.0811

VAL 1441 GLY 1442 0.0284

GLY 1442 LYS 1443 0.0525

LYS 1443 SER 1444 0.0707

SER 1444 MET 1445 0.0824

MET 1445 LEU 1446 0.0367

LEU 1446 ALA 1447 0.0728

ALA 1447 ILE 1448 0.0174

ILE 1448 LEU 1449 0.0707

LEU 1449 ARG 1450 0.0668

ARG 1450 HIS 1451 0.0210

HIS 1451 GLU 1452 0.0736

GLU 1452 ILE 1453 0.1400

ILE 1453 ALA 1454 0.0136

ALA 1454 PRO 1455 0.0711

PRO 1455 LEU 1456 0.0074

LEU 1456 GLU 1457 0.0703

GLU 1457 LEU 1458 0.0250

LEU 1458 MET 1459 0.0526

MET 1459 LEU 1460 0.0337

LEU 1460 GLN 1461 0.0440

GLN 1461 ASP 1462 0.0696

ASP 1462 LYS 1463 0.0305

LYS 1463 LEU 1464 0.0387

LEU 1464 LEU 1465 0.0501

LEU 1465 TYR 1466 0.0292

TYR 1466 ARG 1467 0.0477

ARG 1467 TYR 1468 0.0625

TYR 1468 TYR 1469 0.0962

TYR 1469 THR 1470 0.0381

THR 1470 ASP 1471 0.0190

ASP 1471 ALA 1472 0.0255

ALA 1472 ILE 1473 0.0415

ILE 1473 LYS 1474 0.0269

LYS 1474 TRP 1475 0.0205

TRP 1475 ASP 1476 0.0310

ASP 1476 ARG 1477 0.0434

ARG 1477 SER 1478 0.0389

SER 1478 TYR 1479 0.0248

TYR 1479 GLN 1480 0.0394

GLN 1480 GLN 1481 0.0429

GLN 1481 ILE 1482 0.0322

ILE 1482 ASP 1483 0.0313

ASP 1483 GLN 1484 0.0405

GLN 1484 LEU 1485 0.1489

LEU 1485 VAL 1486 0.0125

VAL 1486 LYS 1487 0.0135

LYS 1487 LEU 1488 0.0156

LEU 1488 HIS 1489 0.0159

HIS 1489 ALA 1490 0.0131

ALA 1490 HIS 1491 0.0134

HIS 1491 LYS 1492 0.0157

LYS 1492 CYS 1493 0.0164

CYS 1493 PRO 1494 0.0166

PRO 1494 THR 1495 0.0148

THR 1495 ALA 1496 0.0056

ALA 1496 LYS 1497 0.0159

LYS 1497 ILE 1498 0.0005

ILE 1498 ILE 1499 0.0082

ILE 1499 GLU 1500 0.0017

GLU 1500 ILE 1501 0.0873

ILE 1501 GLY 1502 0.0123

GLY 1502 ALA 1503 0.0260

ALA 1503 GLY 1504 0.0148

GLY 1504 THR 1505 0.0280

THR 1505 GLY 1506 0.0136

GLY 1506 GLY 1507 0.0195

GLY 1507 CYS 1508 0.0202

CYS 1508 THR 1509 0.0086

THR 1509 ARG 1510 0.0288

ARG 1510 ALA 1511 0.0286

ALA 1511 VAL 1512 0.0149

VAL 1512 LEU 1513 0.0180

LEU 1513 ASP 1514 0.0279

ASP 1514 ALA 1515 0.0270

ALA 1515 LEU 1516 0.0108

LEU 1516 SER 1517 -0.0423

SER 1517 ASN 1518 0.0159

ASN 1518 GLN 1519 0.0176

GLN 1519 GLY 1520 0.0165

GLY 1520 ILE 1521 0.0087

ILE 1521 ALA 1522 0.0167

ALA 1522 ARG 1523 0.0171

ARG 1523 CYS 1524 0.0174

CYS 1524 ALA 1525 0.0082

ALA 1525 GLN 1526 0.0108

GLN 1526 TYR 1527 0.0004

TYR 1527 ASP 1528 0.0158

ASP 1528 PHE 1529 0.0040

PHE 1529 THR 1530 0.0146

THR 1530 ASP 1531 0.0053

ASP 1531 VAL 1532 0.0158

VAL 1532 SER 1533 -0.0195

SER 1533 SER 1534 0.0154

SER 1534 GLY 1535 0.0126

GLY 1535 PHE 1536 0.0269

PHE 1536 PHE 1537 0.0001

PHE 1537 GLU 1538 0.0276

GLU 1538 ALA 1539 0.0177

ALA 1539 ALA 1540 0.0216

ALA 1540 GLN 1541 0.0050

GLN 1541 GLN 1542 0.0255

GLN 1542 LYS 1543 0.0232

LYS 1543 PHE 1544 0.0101

PHE 1544 ALA 1545 0.0124

ALA 1545 ALA 1546 0.0234

ALA 1546 PHE 1547 0.0264

PHE 1547 ASP 1548 0.0253

ASP 1548 ASP 1549 0.0065

ASP 1549 VAL 1550 0.0228

VAL 1550 ILE 1551 0.0072

ILE 1551 ARG 1552 0.0261

ARG 1552 PHE 1553 0.0072

PHE 1553 GLN 1554 0.0255

GLN 1554 LYS 1555 0.0109

LYS 1555 LEU 1556 0.0254

LEU 1556 ASP 1557 0.0139

ASP 1557 ILE 1558 0.0256

ILE 1558 GLU 1559 0.0202

GLU 1559 LYS 1560 0.0129

LYS 1560 ASP 1561 0.0033

ASP 1561 ILE 1562 0.0183

ILE 1562 GLU 1563 0.0061

GLU 1563 MET 1564 0.0205

MET 1564 GLN 1565 0.0255

GLN 1565 GLY 1566 0.0066

GLY 1566 PHE 1567 0.0270

PHE 1567 GLU 1568 0.0140

GLU 1568 CYS 1569 0.0253

CYS 1569 GLY 1570 0.0267

GLY 1570 SER 1571 0.0256

SER 1571 TYR 1572 0.0120

TYR 1572 ASP 1573 0.0273

ASP 1573 LEU 1574 0.0021

LEU 1574 VAL 1575 0.0141

VAL 1575 ILE 1576 0.0087

ILE 1576 ALA 1577 0.0083

ALA 1577 SER 1578 0.0082

SER 1578 GLN 1579 0.0078

GLN 1579 VAL 1580 0.0220

VAL 1580 LEU 1581 0.0925

LEU 1581 HIS 1582 0.0061

HIS 1582 ALA 1583 0.0359

ALA 1583 THR 1584 0.0195

THR 1584 GLY 1585 0.0359

GLY 1585 LYS 1586 0.0276

LYS 1586 MET 1587 0.0356

MET 1587 GLU 1588 0.0151

GLU 1588 HIS 1589 0.0270

HIS 1589 THR 1590 0.0340

THR 1590 MET 1591 0.0332

MET 1591 ALA 1592 0.0099

ALA 1592 ASN 1593 0.0345

ASN 1593 VAL 1594 0.0333

VAL 1594 ARG 1595 0.0225

ARG 1595 LYS 1596 0.0155

LYS 1596 LEU 1597 0.0231

LEU 1597 LEU 1598 0.0280

LEU 1598 LYS 1599 0.0064

LYS 1599 PRO 1600 0.0292

PRO 1600 GLY 1601 0.0226

GLY 1601 GLY 1602 0.0239

GLY 1602 LYS 1603 0.0034

LYS 1603 LEU 1604 0.0089

LEU 1604 LEU 1605 0.0133

LEU 1605 LEU 1606 0.0064

LEU 1606 VAL 1607 0.0063

VAL 1607 GLU 1608 0.0165

GLU 1608 THR 1609 0.0013

THR 1609 THR 1610 0.0292

THR 1610 ARG 1611 0.0000

ARG 1611 ASP 1612 0.0203

ASP 1612 GLU 1613 0.0565

GLU 1613 MET 1614 0.0245

MET 1614 ASP 1615 0.0697

ASP 1615 LEU 1616 0.0104

LEU 1616 GLN 1617 0.0653

GLN 1617 LEU 1618 0.0276

LEU 1618 VAL 1619 0.0512

VAL 1619 PHE 1620 0.0275

PHE 1620 GLY 1621 0.0569

GLY 1621 LEU 1622 0.0640

LEU 1622 LEU 1623 0.0071

LEU 1623 PRO 1624 0.0588

PRO 1624 GLY 1625 0.0237

GLY 1625 TRP 1626 0.0531

TRP 1626 TRP 1627 0.0686

TRP 1627 LEU 1628 0.0152

LEU 1628 SER 1629 -0.0775

SER 1629 SER 1630 0.0525

SER 1630 GLU 1631 0.0536

GLU 1631 GLU 1632 0.0185

GLU 1632 GLU 1633 0.0529

GLU 1633 ARG 1634 0.0536

ARG 1634 GLN 1635 0.0344

GLN 1635 MET 1636 0.0220

MET 1636 SER 1637 0.0380

SER 1637 PRO 1638 0.0107

PRO 1638 SER 1639 0.0525

SER 1639 LEU 1640 0.0424

LEU 1640 SER 1641 0.0506

SER 1641 THR 1642 0.0287

THR 1642 ASN 1643 0.0529

ASN 1643 SER 1644 0.0516

SER 1644 TRP 1645 0.0083

TRP 1645 GLU 1646 0.0272

GLU 1646 LYS 1647 0.0336

LYS 1647 VAL 1648 0.0312

VAL 1648 LEU 1649 0.0204

LEU 1649 LYS 1650 0.0290

LYS 1650 LYS 1651 0.0340

LYS 1651 THR 1652 0.0283

THR 1652 GLY 1653 0.0152

GLY 1653 PHE 1654 0.0278

PHE 1654 ASP 1655 0.0341

ASP 1655 GLY 1656 0.0003

GLY 1656 LEU 1657 0.0231

LEU 1657 ASP 1658 0.0275

ASP 1658 ILE 1659 0.0136

ILE 1659 GLU 1660 0.0031

GLU 1660 LEU 1661 0.0725

LEU 1661 ARG 1662 0.0012

ARG 1662 ASP 1663 0.0311

ASP 1663 CYS 1664 0.0283

CYS 1664 ASP 1665 0.0379

ASP 1665 SER 1666 0.0067

SER 1666 ASP 1667 0.0366

ASP 1667 GLU 1668 0.0104

GLU 1668 PHE 1669 0.0345

PHE 1669 TYR 1670 0.0040

TYR 1670 SER 1671 0.0371

SER 1671 PHE 1672 0.0032

PHE 1672 SER 1673 0.0119

SER 1673 VAL 1674 0.0065

VAL 1674 MET 1675 0.0268

MET 1675 MET 1676 0.0003

MET 1676 ALA 1677 0.0906

ALA 1677 THR 1678 0.0154

THR 1678 ALA 1679 0.0083

ALA 1679 SER 1680 0.0090

SER 1680 SER 1681 0.0179

SER 1681 THR 1682 0.0073

THR 1682 ILE 1683 0.0157

ILE 1683 ALA 1684 0.0122

ALA 1684 SER 1685 0.0162

SER 1685 SER 1686 0.0150

SER 1686 SER 1687 0.0145

SER 1687 MET 1688 0.0036

MET 1688 ALA 1689 0.0175

ALA 1689 PHE 1690 0.0057

PHE 1690 ALA 1691 0.0113

ALA 1691 ILE 1692 0.0083

ILE 1692 VAL 1693 -0.0992

VAL 1693 TYR 1694 0.0033

TYR 1694 GLY 1695 0.0019

GLY 1695 GLU 1696 0.0071

GLU 1696 VAL 1697 0.0093

VAL 1697 PRO 1698 0.0012

PRO 1698 LEU 1699 0.0085

LEU 1699 PRO 1700 0.0089

PRO 1700 ASP 1701 0.0009

ASP 1701 GLN 1702 0.0090

GLN 1702 PHE 1703 0.0082

PHE 1703 LEU 1704 0.0068

LEU 1704 ASP 1705 0.0026

ASP 1705 ASP 1706 0.0095

ASP 1706 MET 1707 0.0093

MET 1707 LYS 1708 0.0031

LYS 1708 THR 1709 0.0160

THR 1709 ALA 1710 0.0084

ALA 1710 ILE 1711 0.0102

ILE 1711 SER 1712 0.0012

SER 1712 SER 1713 0.0105

SER 1713 SER 1714 0.0097

SER 1714 ALA 1715 0.0088

ALA 1715 VAL 1716 0.0027

VAL 1716 SER 1717 0.0087

SER 1717 ASP 1718 0.0076

ASP 1718 PRO 1719 0.0021

PRO 1719 VAL 1720 0.0098

VAL 1720 VAL 1721 0.0025

VAL 1721 GLY 1722 0.0066

GLY 1722 HIS 1723 0.0016

HIS 1723 LEU 1724 0.0092

LEU 1724 ASP 1725 -0.0180

ASP 1725 SER 1726 0.0024

SER 1726 ILE 1727 0.0063

ILE 1727 ASP 1728 0.0062

ASP 1728 ALA 1729 0.0118

ALA 1729 THR 1730 0.0067

THR 1730 GLY 1731 0.0060

GLY 1731 LYS 1732 0.0106

LYS 1732 PHE 1733 0.0099

PHE 1733 CYS 1734 0.0026

CYS 1734 ILE 1735 0.0084

ILE 1735 PHE 1736 0.0016

PHE 1736 ILE 1737 0.0085

ILE 1737 GLU 1738 0.0007

GLU 1738 ASP 1739 0.0071

ASP 1739 PRO 1740 0.0069

PRO 1740 GLU 1741 0.0165

GLU 1741 THR 1742 0.0106

THR 1742 ASP 1743 0.0102

ASP 1743 ILE 1744 0.0094

ILE 1744 LEU 1745 0.0101

LEU 1745 SER 1746 0.0017

SER 1746 SER 1747 0.0092

SER 1747 PRO 1748 0.0051

PRO 1748 ASP 1749 0.0103

ASP 1749 GLU 1750 0.0095

GLU 1750 LYS 1751 0.0033

LYS 1751 SER 1752 0.0096

SER 1752 TYR 1753 0.0104

TYR 1753 ALA 1754 0.0073

ALA 1754 SER 1755 0.0053

SER 1755 ILE 1756 0.0104

ILE 1756 GLN 1757 -0.0080

GLN 1757 LYS 1758 0.0038

LYS 1758 LEU 1759 0.0091

LEU 1759 VAL 1760 0.0100

VAL 1760 THR 1761 0.0087

THR 1761 ARG 1762 0.0045

ARG 1762 CYS 1763 0.0092

CYS 1763 LYS 1764 0.0040

LYS 1764 GLY 1765 0.0073

GLY 1765 LEU 1766 0.0035

LEU 1766 ILE 1767 0.0089

ILE 1767 TRP 1768 0.0005

TRP 1768 VAL 1769 0.0092

VAL 1769 SER 1770 0.0012

SER 1770 ARG 1771 0.0068

ARG 1771 GLY 1772 0.0057

GLY 1772 GLY 1773 -0.0488

GLY 1773 ALA 1774 0.0062

ALA 1774 MET 1775 0.0095

MET 1775 HIS 1776 0.0032

HIS 1776 GLY 1777 0.0069

GLY 1777 THR 1778 0.0088

THR 1778 ARG 1779 0.0092

ARG 1779 PRO 1780 0.0083

PRO 1780 ASN 1781 0.0096

ASN 1781 SER 1782 0.0002

SER 1782 SER 1783 0.0097

SER 1783 LEU 1784 0.0085

LEU 1784 LYS 1785 0.0015

LYS 1785 THR 1786 0.0081

THR 1786 GLY 1787 0.0059

GLY 1787 LEU 1788 0.0089

LEU 1788 LEU 1789 0.0014

LEU 1789 ARG 1790 0.0080

ARG 1790 THR 1791 0.0075

THR 1791 LEU 1792 0.0045

LEU 1792 ARG 1793 0.0037

ARG 1793 LEU 1794 0.0075

LEU 1794 GLU 1795 0.0079

GLU 1795 TYR 1796 0.0017

TYR 1796 THR 1797 0.0048

THR 1797 GLU 1798 0.0032

GLU 1798 LYS 1799 0.0066

LYS 1799 ARG 1800 0.0081

ARG 1800 PHE 1801 0.0012

PHE 1801 ILE 1802 0.0082

ILE 1802 SER 1803 0.0028

SER 1803 LEU 1804 0.0078

LEU 1804 ASP 1805 0.0295

ASP 1805 LEU 1806 0.0111

LEU 1806 ASP 1807 0.0072

ASP 1807 SER 1808 0.0034

SER 1808 ALA 1809 0.0110

ALA 1809 ARG 1810 0.0031

ARG 1810 PRO 1811 0.0107

PRO 1811 GLN 1812 0.0109

GLN 1812 TRP 1813 0.0011

TRP 1813 ASN 1814 0.0092

ASN 1814 HIS 1815 0.0016

HIS 1815 ASP 1816 0.0099

ASP 1816 SER 1817 0.0105

SER 1817 ILE 1818 0.0016

ILE 1818 THR 1819 0.0097

THR 1819 THR 1820 0.0072

THR 1820 ILE 1821 0.0027

ILE 1821 ASN 1822 0.0012

ASN 1822 GLU 1823 0.0079

GLU 1823 VAL 1824 0.0075

VAL 1824 LEU 1825 0.0033

LEU 1825 CYS 1826 0.0047

CYS 1826 GLY 1827 0.0068

GLY 1827 ALA 1828 0.0079

ALA 1828 LEU 1829 0.0008

LEU 1829 ALA 1830 0.0072

ALA 1830 GLN 1831 0.0079

GLN 1831 ASN 1832 0.0018

ASN 1832 ALA 1833 0.0079

ALA 1833 ASP 1834 0.0071

ASP 1834 SER 1835 0.0010

SER 1835 SER 1836 0.0062

SER 1836 ILE 1837 0.0640

ILE 1837 LYS 1838 0.0055

LYS 1838 ASP 1839 0.0026

ASP 1839 SER 1840 0.0048

SER 1840 GLU 1841 0.0019

GLU 1841 PHE 1842 0.0054

PHE 1842 ALA 1843 0.0029

ALA 1843 GLU 1844 0.0051

GLU 1844 GLN 1845 0.0029

GLN 1845 ASP 1846 0.0052

ASP 1846 GLY 1847 0.0001

GLY 1847 GLN 1848 0.0052

GLN 1848 LEU 1849 0.0052

LEU 1849 PHE 1850 0.0029

PHE 1850 VAL 1851 0.0052

VAL 1851 PRO 1852 0.0024

PRO 1852 ARG 1853 -0.1239

ARG 1853 ILE 1854 0.0051

ILE 1854 SER 1855 0.0033

SER 1855 CYS 1856 0.0027

CYS 1856 ASP 1857 0.0024

ASP 1857 ILE 1858 0.0053

ILE 1858 ALA 1859 0.0027

ALA 1859 ARG 1860 0.0075

ARG 1860 ASN 1861 0.0073

ASN 1861 GLU 1862 0.0029

GLU 1862 ASP 1863 0.0050

ASP 1863 LEU 1864 0.0066

LEU 1864 SER 1865 0.0076

SER 1865 SER 1866 0.0015

SER 1866 ASP 1867 0.0060

ASP 1867 SER 1868 0.0069

SER 1868 ASN 1869 0.3760

ASN 1869 SER 1870 0.1252

SER 1870 PRO 1871 0.0886

PRO 1871 ALA 1872 0.0512

ALA 1872 GLN 1873 0.1256

GLN 1873 MET 1874 0.0426

MET 1874 GLU 1875 0.1251

GLU 1875 PRO 1876 0.0579

PRO 1876 PHE 1877 0.0865

PHE 1877 HIS 1878 0.1243

HIS 1878 GLN 1879 0.0324

GLN 1879 PRO 1880 0.1249

PRO 1880 GLY 1881 0.1029

GLY 1881 LYS 1882 0.1245

LYS 1882 LEU 1883 0.0898

LEU 1883 LEU 1884 0.1219

LEU 1884 GLN 1885 0.1281

GLN 1885 MET 1886 0.0919

MET 1886 GLY 1887 0.0871

GLY 1887 ILE 1888 0.0914

ILE 1888 LYS 1889 0.0116

LYS 1889 THR 1890 0.0884

THR 1890 PRO 1891 0.0155

PRO 1891 GLY 1892 0.0863

GLY 1892 LEU 1893 0.0754

LEU 1893 ILE 1894 0.0644

ILE 1894 ASP 1895 0.0443

ASP 1895 THR 1896 0.0760

THR 1896 LEU 1897 0.0573

LEU 1897 GLN 1898 0.0666

GLN 1898 PHE 1899 0.0947

PHE 1899 SER 1900 0.0624

SER 1900 LYS 1901 0.1467

LYS 1901 THR 1902 0.1222

THR 1902 ASP 1903 0.1356

ASP 1903 ALA 1904 0.0682

ALA 1904 THR 1905 0.1308

THR 1905 ASP 1906 0.1244

ASP 1906 ASN 1907 0.0813

ASN 1907 LEU 1908 0.0303

LEU 1908 PRO 1909 0.1061

PRO 1909 ASN 1910 0.0531

ASN 1910 ASP 1911 0.0791

ASP 1911 TYR 1912 0.1098

TYR 1912 ILE 1913 0.1364

ILE 1913 GLU 1914 0.0730

GLU 1914 ILE 1915 0.1269

ILE 1915 GLU 1916 0.1058

GLU 1916 PRO 1917 0.0380

PRO 1917 LYS 1918 0.1133

LYS 1918 ALA 1919 0.1122

ALA 1919 PHE 1920 0.1192

PHE 1920 GLY 1921 0.0897

GLY 1921 LEU 1922 0.0876

LEU 1922 ASN 1923 0.1091

ASN 1923 PHE 1924 0.1178

PHE 1924 ARG 1925 0.1047

ARG 1925 ASP 1926 0.0569

ASP 1926 VAL 1927 0.1127

VAL 1927 MET 1928 0.1194

MET 1928 VAL 1929 0.0791

VAL 1929 ALA 1930 0.0771

ALA 1930 MET 1931 0.1197

MET 1931 GLY 1932 0.1169

GLY 1932 GLN 1933 -0.0340

GLN 1933 LEU 1934 0.1055

LEU 1934 GLU 1935 0.1035

GLU 1935 GLU 1936 0.1194

GLU 1936 SER 1937 0.0680

SER 1937 ILE 1938 0.0827

ILE 1938 MET 1939 0.1149

MET 1939 GLY 1940 0.0909

GLY 1940 PHE 1941 0.0190

PHE 1941 GLU 1942 0.0991

GLU 1942 CYS 1943 0.1173

CYS 1943 ALA 1944 0.1020

ALA 1944 GLY 1945 0.0974

GLY 1945 VAL 1946 0.1206

VAL 1946 VAL 1947 0.1207

VAL 1947 ARG 1948 0.0321

ARG 1948 ARG 1949 0.1002

ARG 1949 VAL 1950 0.0685

VAL 1950 GLY 1951 0.1310

GLY 1951 PRO 1952 0.1094

PRO 1952 SER 1953 0.0630

SER 1953 SER 1954 0.1301

SER 1954 ALA 1955 0.1281

ALA 1955 GLY 1956 0.0363

GLY 1956 HIS 1957 0.1193

HIS 1957 ASN 1958 0.1312

ASN 1958 ILE 1959 0.0289

ILE 1959 LYS 1960 0.0925

LYS 1960 VAL 1961 0.0277

VAL 1961 GLY 1962 0.1311

GLY 1962 ASP 1963 0.0551

ASP 1963 ARG 1964 0.1327

ARG 1964 VAL 1965 0.2105

VAL 1965 CYS 1966 0.1186

CYS 1966 ALA 1967 0.1057

ALA 1967 LEU 1968 0.1177

LEU 1968 LEU 1969 0.0118

LEU 1969 GLY 1970 0.0961

GLY 1970 GLY 1971 0.0816

GLY 1971 GLN 1972 0.0676

GLN 1972 TRP 1973 0.1137

TRP 1973 THR 1974 0.1079

THR 1974 ASN 1975 0.1193

ASN 1975 THR 1976 0.1001

THR 1976 VAL 1977 0.0683

VAL 1977 ARG 1978 0.1103

ARG 1978 VAL 1979 0.0340

VAL 1979 HIS 1980 0.0677

HIS 1980 TRP 1981 0.0039

TRP 1981 HIS 1982 0.0663

HIS 1982 SER 1983 0.0963

SER 1983 VAL 1984 0.1136

VAL 1984 ALA 1985 0.0506

ALA 1985 PRO 1986 0.1139

PRO 1986 ILE 1987 0.1145

ILE 1987 PRO 1988 0.0735

PRO 1988 GLN 1989 0.0945

GLN 1989 ALA 1990 0.1107

ALA 1990 MET 1991 0.0955

MET 1991 ASP 1992 0.0198

ASP 1992 TRP 1993 0.0570

TRP 1993 GLU 1994 0.1151

GLU 1994 THR 1995 0.0075

THR 1995 ALA 1996 0.1143

ALA 1996 ALA 1997 0.0605

ALA 1997 SER 1998 0.0887

SER 1998 ILE 1999 0.0465

ILE 1999 PRO 2000 0.0942

PRO 2000 ILE 2001 0.0842

ILE 2001 VAL 2002 0.0768

VAL 2002 PHE 2003 0.0183

PHE 2003 VAL 2004 0.0974

VAL 2004 THR 2005 0.0891

THR 2005 ALA 2006 0.0372

ALA 2006 TYR 2007 0.0612

TYR 2007 ILE 2008 0.0886

ILE 2008 SER 2009 0.1001

SER 2009 LEU 2010 0.0236

LEU 2010 VAL 2011 0.0688

VAL 2011 LYS 2012 0.0899

LYS 2012 ILE 2013 0.1515

ILE 2013 ALA 2014 0.0547

ALA 2014 ARG 2015 0.0171

ARG 2015 MET 2016 0.0626

MET 2016 GLN 2017 0.0038

GLN 2017 ALA 2018 0.0485

ALA 2018 GLY 2019 0.0658

GLY 2019 GLU 2020 0.0212

GLU 2020 THR 2021 0.0306

THR 2021 VAL 2022 0.0100

VAL 2022 LEU 2023 0.0144

LEU 2023 ILE 2024 0.0391

ILE 2024 HIS 2025 0.0046

HIS 2025 ALA 2026 0.0451

ALA 2026 ALA 2027 0.0172

ALA 2027 SER 2028 0.0549

SER 2028 GLY 2029 -0.0557

GLY 2029 GLY 2030 0.0755

GLY 2030 VAL 2031 0.0715

VAL 2031 GLY 2032 0.0636

GLY 2032 GLN 2033 0.0629

GLN 2033 ALA 2034 0.0753

ALA 2034 ALA 2035 0.0703

ALA 2035 ILE 2036 0.0575

ILE 2036 ILE 2037 0.0698

ILE 2037 LEU 2038 0.0750

LEU 2038 ALA 2039 0.0695

ALA 2039 LYS 2040 0.0528

LYS 2040 HIS 2041 0.0742

HIS 2041 VAL 2042 0.0748

VAL 2042 GLY 2043 0.0624

GLY 2043 ALA 2044 0.0532

ALA 2044 GLU 2045 -0.0077

GLU 2045 ILE 2046 0.0077

ILE 2046 PHE 2047 0.0438

PHE 2047 ALA 2048 0.0164

ALA 2048 THR 2049 0.0120

THR 2049 VAL 2050 0.0481

VAL 2050 GLY 2051 0.0138

GLY 2051 THR 2052 0.0797

THR 2052 ASP 2053 0.0431

ASP 2053 GLU 2054 0.0805

GLU 2054 LYS 2055 0.0768

LYS 2055 ARG 2056 0.0347

ARG 2056 ASP 2057 0.0726

ASP 2057 LEU 2058 0.0809

LEU 2058 LEU 2059 0.0527

LEU 2059 ILE 2060 0.0477

ILE 2060 LYS 2061 0.1198

LYS 2061 GLU 2062 0.0756

GLU 2062 TYR 2063 0.0625

TYR 2063 LYS 2064 0.0475

LYS 2064 ILE 2065 0.0689

ILE 2065 PRO 2066 0.0709

PRO 2066 ASP 2067 0.0320

ASP 2067 ASP 2068 0.0712

ASP 2068 HIS 2069 0.0747

HIS 2069 ILE 2070 0.0075

ILE 2070 PHE 2071 0.0353

PHE 2071 SER 2072 0.0001

SER 2072 SER 2073 0.0619

SER 2073 ARG 2074 0.0258

ARG 2074 ASN 2075 0.0651

ASN 2075 ALA 2076 0.0495

ALA 2076 LEU 2077 0.0737

LEU 2077 PHE 2078 0.0315

PHE 2078 ALA 2079 0.0444

ALA 2079 LYS 2080 0.0441

LYS 2080 SER 2081 0.0419

SER 2081 ILE 2082 0.0384

ILE 2082 ARG 2083 0.0430

ARG 2083 GLN 2084 0.0443

GLN 2084 ARG 2085 0.0402

ARG 2085 THR 2086 0.0415

THR 2086 ASN 2087 0.0428

ASN 2087 GLY 2088 0.0283

GLY 2088 LYS 2089 0.0454

LYS 2089 GLY 2090 0.0166

GLY 2090 VAL 2091 0.0495

VAL 2091 ASP 2092 0.0407

ASP 2092 VAL 2093 -0.0012

VAL 2093 VAL 2094 0.0007

VAL 2094 LEU 2095 0.0193

LEU 2095 ASN 2096 0.0097

ASN 2096 CYS 2097 0.0033

CYS 2097 LEU 2098 0.0270

LEU 2098 ALA 2099 0.0261

ALA 2099 GLY 2100 0.0327

GLY 2100 GLY 2101 0.0273

GLY 2101 LEU 2102 0.0290

LEU 2102 LEU 2103 0.0235

LEU 2103 GLN 2104 0.0274

GLN 2104 GLU 2105 0.0316

GLU 2105 SER 2106 0.0274

SER 2106 PHE 2107 0.0237

PHE 2107 ASP 2108 0.0303

ASP 2108 CYS 2109 0.0364

CYS 2109 LEU 2110 0.0206

LEU 2110 ALA 2111 0.0005

ALA 2111 ASP 2112 0.0154

ASP 2112 PHE 2113 0.0235

PHE 2113 GLY 2114 0.0082

GLY 2114 ARG 2115 0.0092

ARG 2115 PHE 2116 0.0037

PHE 2116 ILE 2117 0.0117

ILE 2117 GLU 2118 0.0034

GLU 2118 ILE 2119 0.0111

ILE 2119 GLY 2120 0.0124

GLY 2120 LYS 2121 0.0160

LYS 2121 ARG 2122 0.0200

ARG 2122 ASP 2123 0.0130

ASP 2123 ILE 2124 0.0234

ILE 2124 GLU 2125 0.0238

GLU 2125 LEU 2126 0.0115

LEU 2126 ASN 2127 0.0013

ASN 2127 HIS 2128 0.0103

HIS 2128 CYS 2129 0.0009

CYS 2129 LEU 2130 0.0063

LEU 2130 ASN 2131 0.0036

ASN 2131 MET 2132 0.0049

MET 2132 GLY 2133 0.0064

GLY 2133 MET 2134 0.0112

MET 2134 PHE 2135 0.0100

PHE 2135 ALA 2136 0.0026

ALA 2136 ARG 2137 0.0113

ARG 2137 SER 2138 0.0113

SER 2138 ALA 2139 0.0014

ALA 2139 THR 2140 0.0072

THR 2140 PHE 2141 -0.0172

PHE 2141 THR 2142 0.0543

THR 2142 ALA 2143 0.0019

ALA 2143 VAL 2144 0.0742

VAL 2144 ASP 2145 0.0111

ASP 2145 LEU 2146 0.0778

LEU 2146 ILE 2147 0.0248

ILE 2147 ALA 2148 0.0630

ALA 2148 ILE 2149 0.0396

ILE 2149 GLY 2150 0.0451

GLY 2150 ARG 2151 0.0656

ARG 2151 ASP 2152 0.0308

ASP 2152 ARG 2153 0.0356

ARG 2153 SER 2154 0.0679

SER 2154 TYR 2155 0.0239

TYR 2155 MET 2156 0.0707

MET 2156 PHE 2157 0.2577

PHE 2157 ALA 2158 0.0808

ALA 2158 GLU 2159 0.0176

GLU 2159 ALA 2160 0.0908

ALA 2160 LEU 2161 0.0656

LEU 2161 PRO 2162 0.0660

PRO 2162 LYS 2163 0.0300

LYS 2163 ILE 2164 0.0786

ILE 2164 MET 2165 0.0879

MET 2165 THR 2166 0.0126

THR 2166 LEU 2167 0.0810

LEU 2167 LEU 2168 0.0582

LEU 2168 GLN 2169 0.0873

GLN 2169 GLU 2170 0.0053

GLU 2170 LYS 2171 0.0885

LYS 2171 ALA 2172 0.0758

ALA 2172 ILE 2173 -0.0786

ILE 2173 ARG 2174 0.0582

ARG 2174 PRO 2175 0.0007

PRO 2175 VAL 2176 0.0806

VAL 2176 THR 2177 0.0990

THR 2177 PRO 2178 0.0432

PRO 2178 ILE 2179 0.0641

ILE 2179 SER 2180 0.0223

SER 2180 ILE 2181 0.0734

ILE 2181 TYR 2182 0.0003

TYR 2182 LYS 2183 0.0632

LYS 2183 ILE 2184 0.0744

ILE 2184 GLY 2185 0.0400

GLY 2185 ASP 2186 0.0897

ASP 2186 ILE 2187 0.1000

ILE 2187 GLU 2188 0.0766

GLU 2188 THR 2189 -0.0141

THR 2189 ALA 2190 0.0469

ALA 2190 PHE 2191 0.0949

PHE 2191 ARG 2192 0.1046

ARG 2192 LEU 2193 0.0196

LEU 2193 MET 2194 0.0924

MET 2194 GLN 2195 0.0752

GLN 2195 ALA 2196 0.0946

ALA 2196 GLY 2197 0.0179

GLY 2197 LYS 2198 0.0994

LYS 2198 HIS 2199 0.0960

HIS 2199 MET 2200 0.0096

MET 2200 GLY 2201 0.0974

GLY 2201 LYS 2202 0.0525

LYS 2202 ILE 2203 0.0128

ILE 2203 VAL 2204 0.1002

VAL 2204 ILE 2205 0.0130

ILE 2205 THR 2206 0.0887

THR 2206 ALA 2207 0.0165

ALA 2207 PRO 2208 0.0956

PRO 2208 GLU 2209 0.0247

GLU 2209 ASP 2210 0.0872

ASP 2210 ALA 2211 0.0938

ALA 2211 MET 2212 0.0558

MET 2212 VAL 2213 0.1028

VAL 2213 PRO 2214 0.0743

PRO 2214 VAL 2215 0.0784

VAL 2215 ILE 2216 0.0720

ILE 2216 THR 2217 0.0519

THR 2217 ARG 2218 0.1036

ARG 2218 PRO 2219 0.0161

PRO 2219 PRO 2220 0.1038

PRO 2220 LYS 2221 0.5785

LYS 2221 LEU 2222 0.0037

LEU 2222 GLN 2223 0.0005

GLN 2223 LEU 2224 0.0035

LEU 2224 ARG 2225 0.0001

ARG 2225 PRO 2226 0.0038

PRO 2226 ASP 2227 0.0016

ASP 2227 ALA 2228 0.0028

ALA 2228 SER 2229 0.0028

SER 2229 TYR 2230 0.0002

TYR 2230 LEU 2231 0.0035

LEU 2231 ILE 2232 0.0004

ILE 2232 VAL 2233 0.0036

VAL 2233 GLY 2234 0.0019

GLY 2234 GLY 2235 0.0035

GLY 2235 LEU 2236 0.0034

LEU 2236 GLY 2237 0.0624

GLY 2237 GLY 2238 0.0016

GLY 2238 ILE 2239 0.0008

ILE 2239 GLY 2240 0.0023

GLY 2240 ARG 2241 0.0022

ARG 2241 SER 2242 0.0004

SER 2242 LEU 2243 0.0021

LEU 2243 CYS 2244 0.0019

CYS 2244 LYS 2245 0.0020

LYS 2245 ASN 2246 0.0005

ASN 2246 PHE 2247 0.0026

PHE 2247 VAL 2248 0.0023

VAL 2248 GLU 2249 0.0013

GLU 2249 ASN 2250 0.0016

ASN 2250 GLY 2251 0.0024

GLY 2251 ALA 2252 0.0007

ALA 2252 ARG 2253 0.0536

ARG 2253 SER 2254 0.0012

SER 2254 LEU 2255 0.0027

LEU 2255 VAL 2256 0.0017

VAL 2256 LEU 2257 0.0028

LEU 2257 LEU 2258 0.0018

LEU 2258 SER 2259 0.0028

SER 2259 ARG 2260 0.0011

ARG 2260 ASN 2261 0.0028

ASN 2261 ALA 2262 0.0026

ALA 2262 ASN 2263 0.0017

ASN 2263 VAL 2264 0.0014

VAL 2264 SER 2265 0.0027

SER 2265 GLN 2266 0.0030

GLN 2266 GLN 2267 0.0008

GLN 2267 SER 2268 0.0025

SER 2268 GLY 2269 -0.0041

GLY 2269 GLU 2270 0.0006

GLU 2270 PHE 2271 0.0025

PHE 2271 LEU 2272 0.0021

LEU 2272 ASP 2273 0.0012

ASP 2273 GLU 2274 0.0022

GLU 2274 LEU 2275 0.0016

LEU 2275 ARG 2276 0.0030

ARG 2276 SER 2277 0.0002

SER 2277 THR 2278 0.0031

THR 2278 GLY 2279 0.0019

GLY 2279 CYS 2280 0.0011

CYS 2280 ILE 2281 0.0006

ILE 2281 VAL 2282 0.0025

VAL 2282 GLY 2283 0.0001

GLY 2283 VAL 2284 0.0030

VAL 2284 VAL 2285 -0.2077

VAL 2285 ASP 2286 0.0032

ASP 2286 CYS 2287 0.0035

CYS 2287 ASP 2288 0.0041

ASP 2288 ILE 2289 0.0016

ILE 2289 SER 2290 0.0040

SER 2290 SER 2291 0.0012

SER 2291 LYS 2292 0.0040

LYS 2292 THR 2293 0.0009

THR 2293 GLN 2294 0.0040

GLN 2294 VAL 2295 0.0006

VAL 2295 GLU 2296 0.0036

GLU 2296 ALA 2297 0.0019

ALA 2297 THR 2298 0.0023

THR 2298 MET 2299 0.0022

MET 2299 LEU 2300 0.0019

LEU 2300 ARG 2301 0.0300

ARG 2301 LEU 2302 0.0014

LEU 2302 LYS 2303 0.0043

LYS 2303 LYS 2304 0.0009

LYS 2304 ASP 2305 0.0041

ASP 2305 MET 2306 0.0005

MET 2306 LEU 2307 0.0026

LEU 2307 PRO 2308 0.0030

PRO 2308 ILE 2309 0.0026

ILE 2309 ARG 2310 0.0007

ARG 2310 GLY 2311 0.0031

GLY 2311 ILE 2312 0.0042

ILE 2312 VAL 2313 0.0035

VAL 2313 HIS 2314 0.0042

HIS 2314 ALA 2315 0.0042

ALA 2315 GLY 2316 0.0027

GLY 2316 MET 2317 -0.0364

MET 2317 VAL 2318 0.0147

VAL 2318 LEU 2319 0.0061

LEU 2319 GLN 2320 0.0137

GLN 2320 ASP 2321 0.0029

ASP 2321 SER 2322 0.0096

SER 2322 VAL 2323 0.0008

VAL 2323 PHE 2324 0.0143

PHE 2324 GLU 2325 0.0133

GLU 2325 ARG 2326 0.0038

ARG 2326 MET 2327 0.0091

MET 2327 SER 2328 0.0080

SER 2328 LEU 2329 0.0133

LEU 2329 ASP 2330 0.0033

ASP 2330 ASP 2331 0.0121

ASP 2331 TYR 2332 0.0106

TYR 2332 ASN 2333 0.0278

ASN 2333 THR 2334 0.0108

THR 2334 ALA 2335 0.0046

ALA 2335 ILE 2336 0.0120

ILE 2336 ARG 2337 0.0020

ARG 2337 PRO 2338 0.0128

PRO 2338 LYS 2339 0.0019

LYS 2339 VAL 2340 0.0127

VAL 2340 GLN 2341 0.0019

GLN 2341 GLY 2342 0.0116

GLY 2342 SER 2343 0.0064

SER 2343 TRP 2344 0.0124

TRP 2344 ASN 2345 0.0002

ASN 2345 LEU 2346 0.0125

LEU 2346 HIS 2347 0.0074

HIS 2347 SER 2348 0.0074

SER 2348 GLY 2349 0.0066

GLY 2349 LEU 2350 0.0055

LEU 2350 SER 2351 0.0054

SER 2351 ASP 2352 0.0026

ASP 2352 CYS 2353 0.0058

CYS 2353 ASP 2354 0.0040

ASP 2354 LEU 2355 0.0046

LEU 2355 ASP 2356 0.0043

ASP 2356 PHE 2357 0.0048

PHE 2357 PHE 2358 0.0060

PHE 2358 ILE 2359 0.0046

ILE 2359 MET 2360 0.0059

MET 2360 LEU 2361 0.0055

LEU 2361 SER 2362 0.0032

SER 2362 SER 2363 0.0037

SER 2363 LEU 2364 0.0003

LEU 2364 ALA 2365 -0.1261

ALA 2365 GLY 2366 0.0123

GLY 2366 VAL 2367 0.0060

VAL 2367 SER 2368 0.0071

SER 2368 GLY 2369 0.0125

GLY 2369 SER 2370 0.0120

SER 2370 ALA 2371 0.0113

ALA 2371 SER 2372 0.0059

SER 2372 GLN 2373 0.0077

GLN 2373 ALA 2374 0.0124

ALA 2374 ASN 2375 0.0004

ASN 2375 TYR 2376 0.0123

TYR 2376 THR 2377 0.0050

THR 2377 ALA 2378 0.0117

ALA 2378 GLY 2379 0.0022

GLY 2379 GLY 2380 0.0110

GLY 2380 ALA 2381 -0.0018

ALA 2381 TYR 2382 0.0026

TYR 2382 GLN 2383 0.0066

GLN 2383 ASP 2384 0.0023

ASP 2384 ALA 2385 0.0081

ALA 2385 LEU 2386 0.0003

LEU 2386 ALA 2387 0.0079

ALA 2387 LYS 2388 0.0047

LYS 2388 TYR 2389 0.0051

TYR 2389 ARG 2390 0.0034

ARG 2390 ARG 2391 0.0053

ARG 2391 ALA 2392 0.0073

ALA 2392 GLN 2393 0.0005

GLN 2393 GLY 2394 0.0079

GLY 2394 LEU 2395 0.0058

LEU 2395 SER 2396 0.0081

SER 2396 ALA 2397 0.0322

ALA 2397 VAL 2398 0.0029

VAL 2398 SER 2399 0.0035

SER 2399 ILE 2400 0.0038

ILE 2400 ASP 2401 0.0024

ASP 2401 LEU 2402 0.0030

LEU 2402 GLY 2403 0.0029

GLY 2403 MET 2404 0.0034

MET 2404 VAL 2405 0.0016

VAL 2405 GLN 2406 0.0041

GLN 2406 SER 2407 0.0005

SER 2407 VAL 2408 0.0027

VAL 2408 GLY 2409 0.0037

GLY 2409 TYR 2410 0.0032

TYR 2410 VAL 2411 0.0015

VAL 2411 ALA 2412 0.0028

ALA 2412 GLU 2413 -0.0505

GLU 2413 THR 2414 0.0073

THR 2414 LYS 2415 0.0083

LYS 2415 GLY 2416 0.0009

GLY 2416 VAL 2417 0.0090

VAL 2417 ALA 2418 0.0077

ALA 2418 GLU 2419 0.0060

GLU 2419 ARG 2420 0.0092

ARG 2420 LEU 2421 0.0091

LEU 2421 VAL 2422 0.0066

VAL 2422 ARG 2423 0.0071

ARG 2423 MET 2424 0.0097

MET 2424 GLY 2425 0.0080

GLY 2425 TYR 2426 0.0037

TYR 2426 SER 2427 0.0096

SER 2427 PRO 2428 0.0016

PRO 2428 ILE 2429 -0.0623

ILE 2429 SER 2430 0.0039

SER 2430 GLU 2431 0.0015

GLU 2431 MET 2432 0.0038

MET 2432 GLU 2433 0.0026

GLU 2433 VAL 2434 0.0024

VAL 2434 LEU 2435 0.0042

LEU 2435 LYS 2436 0.0011

LYS 2436 ILE 2437 0.0047

ILE 2437 VAL 2438 0.0010

VAL 2438 GLU 2439 0.0050

GLU 2439 HIS 2440 0.0010

HIS 2440 ALA 2441 0.0042

ALA 2441 ILE 2442 0.0030

ILE 2442 THR 2443 0.0028

THR 2443 ASN 2444 0.0017

ASN 2444 PRO 2445 -0.1386

PRO 2445 PRO 2446 0.0003

PRO 2446 PRO 2447 0.0038

PRO 2447 GLU 2448 0.0024

GLU 2448 ALA 2449 0.0038

ALA 2449 SER 2450 0.0007

SER 2450 SER 2451 0.0036

SER 2451 ALA 2452 0.0013

ALA 2452 GLN 2453 0.0033

GLN 2453 ILE 2454 0.0039

ILE 2454 ILE 2455 0.0025

ILE 2455 THR 2456 0.0038

THR 2456 GLY 2457 0.0034

GLY 2457 ILE 2458 0.0001

ILE 2458 SER 2459 0.0028

SER 2459 THR 2460 0.0022

THR 2460 LYS 2461 0.0946

LYS 2461 PRO 2462 0.0011

PRO 2462 GLY 2463 0.0045

GLY 2463 ARG 2464 0.0045

ARG 2464 HIS 2465 0.0010

HIS 2465 TRP 2466 0.0040

TRP 2466 THR 2467 0.0032

THR 2467 GLU 2468 0.0028

GLU 2468 SER 2469 0.0012

SER 2469 SER 2470 0.0046

SER 2470 TRP 2471 0.0024

TRP 2471 LEU 2472 0.0029

LEU 2472 GLN 2473 0.0028

GLN 2473 ASP 2474 0.0026

ASP 2474 ALA 2475 0.0041

ALA 2475 ARG 2476 0.0015

ARG 2476 PHE 2477 -0.0217

PHE 2477 ALA 2478 0.0017

ALA 2478 THR 2479 0.0039

THR 2479 LEU 2480 0.0039

LEU 2480 ARG 2481 0.0013

ARG 2481 GLU 2482 0.0028

GLU 2482 ARG 2483 0.0036

ARG 2483 ALA 2484 0.0034

ALA 2484 ARG 2485 0.0013

ARG 2485 ASP 2486 0.0039

ASP 2486 VAL 2487 0.0037

VAL 2487 LYS 2488 0.0017

LYS 2488 GLU 2489 0.0024

GLU 2489 LEU 2490 0.0039

LEU 2490 SER 2491 0.0031

SER 2491 ASN 2492 0.0009

ASN 2492 SER 2493 -0.0797

SER 2493 GLN 2494 0.0115

GLN 2494 ASN 989 -0.2393

ASN 989 LYS 990 0.1101

LYS 990 ALA 991 0.0812

ALA 991 HIS 992 0.0560

HIS 992 ARG 993 0.1155

ARG 993 GLN 994 0.1141

GLN 994 ARG 995 0.0542

ARG 995 VAL 996 0.0956

VAL 996 HIS 997 0.0337

HIS 997 PRO 998 0.0678

PRO 998 PRO 999 0.1019

PRO 999 HIS 1000 0.0883

HIS 1000 ASP 1001 0.0232

ASP 1001 LEU 1002 0.1111

LEU 1002 LEU 1003 0.0009

LEU 1003 GLY 1004 0.1094

GLY 1004 SER 1005 -0.1531

SER 1005 LEU 1006 0.0280

LEU 1006 ILE 1007 0.0664

ILE 1007 VAL 1008 0.0324

VAL 1008 GLY 1009 0.0220

GLY 1009 ARG 1010 0.0879

ARG 1010 ASP 1011 0.0788

ASP 1011 LEU 1012 0.0703

LEU 1012 ARG 1013 0.0923

ARG 1013 GLU 1014 0.0644

GLU 1014 PRO 1015 0.0646

PRO 1015 THR 1016 0.0548

THR 1016 TRP 1017 0.0406

TRP 1017 ARG 1018 0.0798

ARG 1018 HIS 1019 0.0067

HIS 1019 PHE 1020 0.0686

PHE 1020 ILE 1021 0.1866

ILE 1021 ARG 1022 0.0880

ARG 1022 VAL 1023 0.0091

VAL 1023 GLN 1024 0.0908

GLN 1024 ASP 1025 0.0798

ASP 1025 ILE 1026 0.0483

ILE 1026 PRO 1027 0.0298

PRO 1027 TRP 1028 0.0602

TRP 1028 ILE 1029 0.0839

ILE 1029 ARG 1030 0.0679

ARG 1030 ASP 1031 0.0357

ASP 1031 HIS 1032 0.0886

HIS 1032 VAL 1033 0.0936

VAL 1033 VAL 1034 0.0951

VAL 1034 GLN 1035 0.0915

GLN 1035 SER 1036 0.0935

SER 1036 ALA 1037 0.2111

ALA 1037 LEU 1038 0.0765

LEU 1038 VAL 1039 0.0781

VAL 1039 TYR 1040 0.0596

TYR 1040 PRO 1041 0.0770

PRO 1041 GLY 1042 0.0795

GLY 1042 ALA 1043 0.0931

ALA 1043 GLY 1044 0.0581

GLY 1044 PHE 1045 0.0461

PHE 1045 ILE 1046 0.0927

ILE 1046 CYS 1047 0.0933

CYS 1047 MET 1048 0.0333

MET 1048 ALA 1049 0.0755

ALA 1049 MET 1050 0.0884

MET 1050 GLU 1051 0.0843

GLU 1051 ALA 1052 0.0307

ALA 1052 MET 1053 0.1120

MET 1053 VAL 1054 0.0877

VAL 1054 GLN 1055 0.0651

GLN 1055 LEU 1056 0.0441

LEU 1056 HIS 1057 0.0936

HIS 1057 GLU 1058 0.0937

GLU 1058 LEU 1059 0.0384

LEU 1059 ARG 1060 0.0689

ARG 1060 ASP 1061 0.0901

ASP 1061 SER 1062 0.0876

SER 1062 GLN 1063 0.0900

GLN 1063 SER 1064 0.0045

SER 1064 ARG 1065 0.0885

ARG 1065 LYS 1066 0.0012

LYS 1066 VAL 1067 0.0755

VAL 1067 ALA 1068 0.0601

ALA 1068 GLY 1069 0.1011

GLY 1069 TYR 1070 0.0878

TYR 1070 ARG 1071 0.0897

ARG 1071 LEU 1072 0.0889

LEU 1072 ALA 1073 0.0899

ALA 1073 GLU 1074 0.0889

GLU 1074 VAL 1075 0.0767

VAL 1075 ASP 1076 0.0868

ASP 1076 ILE 1077 0.0693

ILE 1077 LEU 1078 0.0799

LEU 1078 ARG 1079 0.0763

ARG 1079 ALA 1080 0.0589

ALA 1080 MET 1081 0.0718

MET 1081 LEU 1082 0.0693

LEU 1082 ILE 1083 0.0896

ILE 1083 PRO 1084 0.0897

PRO 1084 ASP 1085 -0.0389

ASP 1085 THR 1086 0.0393

THR 1086 SER 1087 0.0530

SER 1087 GLU 1088 0.0341

GLU 1088 GLY 1089 0.0675

GLY 1089 LEU 1090 0.0682

LEU 1090 GLU 1091 0.0110

GLU 1091 ALA 1092 0.0809

ALA 1092 HIS 1093 0.0346

HIS 1093 ILE 1094 0.0805

ILE 1094 SER 1095 0.0238

SER 1095 LEU 1096 0.0766

LEU 1096 ARG 1097 0.0445

ARG 1097 PRO 1098 0.0724

PRO 1098 CYS 1099 0.0736

CYS 1099 SER 1100 0.0304

SER 1100 THR 1101 -0.0656

THR 1101 LYS 1102 0.0633

LYS 1102 LEU 1103 0.0109

LEU 1103 LEU 1104 0.0649

LEU 1104 LEU 1105 0.0543

LEU 1105 THR 1106 0.0547

THR 1106 ASN 1107 0.0607

ASN 1107 GLU 1108 0.0613

GLU 1108 TRP 1109 0.0267

TRP 1109 TYR 1110 0.0638

TYR 1110 ASP 1111 0.0510

ASP 1111 PHE 1112 0.0436

PHE 1112 CYS 1113 0.0560

CYS 1113 VAL 1114 0.0367

VAL 1114 SER 1115 0.0650

SER 1115 SER 1116 0.0580

SER 1116 VAL 1117 0.1239

VAL 1117 GLY 1118 0.0616

GLY 1118 ASP 1119 0.0832

ASP 1119 ASP 1120 0.0424

ASP 1120 ASP 1121 0.0569

ASP 1121 LYS 1122 0.0825

LYS 1122 PHE 1123 0.0820

PHE 1123 VAL 1124 0.0310

VAL 1124 ASP 1125 0.0836

ASP 1125 HIS 1126 0.0207

HIS 1126 CYS 1127 0.0796

CYS 1127 ARG 1128 0.0385

ARG 1128 GLY 1129 0.0819

GLY 1129 ARG 1130 0.0599

ARG 1130 ILE 1131 0.0833

ILE 1131 THR 1132 0.0679

THR 1132 ILE 1133 0.1688

ILE 1133 GLU 1134 0.0526

GLU 1134 PHE 1135 0.0522

PHE 1135 ASP 1136 0.0473

ASP 1136 THR 1137 0.0362

THR 1137 SER 1138 0.0557

SER 1138 GLY 1139 0.0555

GLY 1139 SER 1140 0.0398

SER 1140 ALA 1141 0.0136

ALA 1141 ASP 1142 0.0254

ASP 1142 THR 1143 0.0556

THR 1143 PRO 1144 0.0004

PRO 1144 ARG 1145 0.0518

ARG 1145 THR 1146 0.0242

THR 1146 SER 1147 0.0144

SER 1147 LEU 1148 0.0397

LEU 1148 ARG 1149 0.0834

ARG 1149 GLU 1150 0.1234

GLU 1150 ARG 1151 0.0815

ARG 1151 SER 1152 0.1229

SER 1152 ARG 1153 0.0232

ARG 1153 SER 1154 0.1253

SER 1154 THR 1155 0.0935

THR 1155 GLY 1156 0.0945

GLY 1156 LEU 1157 0.1282

LEU 1157 MET 1158 0.0541

MET 1158 ARG 1159 0.0973

ARG 1159 SER 1160 0.1076

SER 1160 VAL 1161 0.0149

VAL 1161 ASP 1162 0.0905

ASP 1162 PRO 1163 0.0448

PRO 1163 SER 1164 0.0968

SER 1164 ASN 1165 0.1333

ASN 1165 LEU 1166 0.0368

LEU 1166 TYR 1167 0.0603

TYR 1167 SER 1168 0.0805

SER 1168 PHE 1169 0.0920

PHE 1169 LEU 1170 0.0131

LEU 1170 ARG 1171 0.0905

ARG 1171 ALA 1172 0.0824

ALA 1172 GLN 1173 0.0600

GLN 1173 GLY 1174 0.0418

GLY 1174 ILE 1175 0.0934

ILE 1175 TYR 1176 0.0910

TYR 1176 HIS 1177 0.0922

HIS 1177 GLY 1178 0.0932

GLY 1178 PRO 1179 0.0684

PRO 1179 ILE 1180 0.0573

ILE 1180 PHE 1181 0.0837

PHE 1181 GLN 1182 0.0023

GLN 1182 ASN 1183 0.0886

ASN 1183 LEU 1184 0.0444

LEU 1184 LYS 1185 0.0198

LYS 1185 THR 1186 0.0602

THR 1186 ILE 1187 0.0931

ILE 1187 SER 1188 0.0584

SER 1188 SER 1189 0.0890

SER 1189 ARG 1190 0.0851

ARG 1190 LYS 1191 0.0809

LYS 1191 ASP 1192 0.0459

ASP 1192 HIS 1193 0.0932

HIS 1193 SER 1194 0.0930

SER 1194 GLU 1195 0.0930

GLU 1195 SER 1196 0.0768

SER 1196 SER 1197 -0.0194

SER 1197 PHE 1198 0.0595

PHE 1198 VAL 1199 0.0797

VAL 1199 VAL 1200 0.0119

VAL 1200 ALA 1201 0.0900

ALA 1201 ASN 1202 0.0826

ASN 1202 THR 1203 0.0360

THR 1203 ALA 1204 0.0724

ALA 1204 SER 1205 0.0438

SER 1205 VAL 1206 0.0821

VAL 1206 MET 1207 0.0054

MET 1207 PRO 1208 0.0720

PRO 1208 ASN 1209 0.0890

ASN 1209 GLY 1210 0.0683

GLY 1210 PHE 1211 0.0217

PHE 1211 GLN 1212 0.0895

GLN 1212 SER 1213 -0.0200

SER 1213 PRO 1214 0.0886

PRO 1214 HIS 1215 0.0890

HIS 1215 VAL 1216 0.0870

VAL 1216 ILE 1217 0.0435

ILE 1217 HIS 1218 0.0877

HIS 1218 PRO 1219 0.0923

PRO 1219 THR 1220 0.0116

THR 1220 THR 1221 0.0868

THR 1221 LEU 1222 0.0752

LEU 1222 ASP 1223 0.0814

ASP 1223 SER 1224 0.0168

SER 1224 ILE 1225 0.0911

ILE 1225 PHE 1226 0.0869

PHE 1226 GLN 1227 0.0314

GLN 1227 GLY 1228 0.0722

GLY 1228 ALA 1229 0.0002

ALA 1229 TYR 1230 0.0681

TYR 1230 THR 1231 0.0266

THR 1231 ALA 1232 0.0855

ALA 1232 LEU 1233 0.0867

LEU 1233 PRO 1234 0.0221

PRO 1234 GLY 1235 0.0746

GLY 1235 ALA 1236 0.0499

ALA 1236 GLY 1237 0.0477

GLY 1237 LEU 1238 0.0682

LEU 1238 ASP 1239 0.0859

ASP 1239 GLN 1240 0.0041

GLN 1240 ASN 1241 0.0746

ASN 1241 THR 1242 0.0118

THR 1242 ALA 1243 0.0603

ALA 1243 MET 1244 0.0803

MET 1244 ILE 1245 0.2758

ILE 1245 PRO 1246 0.0601

PRO 1246 ARG 1247 0.0591

ARG 1247 SER 1248 0.0777

SER 1248 ILE 1249 0.0941

ILE 1249 GLN 1250 0.0856

GLN 1250 GLU 1251 0.0917

GLU 1251 LEU 1252 0.0923

LEU 1252 TYR 1253 0.0914

TYR 1253 LEU 1254 0.0941

LEU 1254 SER 1255 0.0940

SER 1255 SER 1256 0.0702

SER 1256 ALA 1257 0.0352

ALA 1257 LEU 1258 0.0746

LEU 1258 THR 1259 0.0933

THR 1259 SER 1260 0.0942

SER 1260 ASP 1261 0.0558

ASP 1261 VAL 1262 0.0635

VAL 1262 GLY 1263 0.0109

GLY 1263 GLN 1264 0.0836

GLN 1264 CYS 1265 0.0573

CYS 1265 LEU 1266 0.0696

LEU 1266 VAL 1267 0.0656

VAL 1267 SER 1268 0.0722

SER 1268 ASP 1269 0.0787

ASP 1269 THR 1270 0.0780

THR 1270 SER 1271 0.0847

SER 1271 LEU 1272 0.0837

LEU 1272 ILE 1273 0.0489

ILE 1273 ARG 1274 0.0847

ARG 1274 TYR 1275 0.0751

TYR 1275 ASP 1276 0.0831

ASP 1276 GLY 1277 0.0427

GLY 1277 GLN 1278 0.0097

GLN 1278 SER 1279 0.0727

SER 1279 PHE 1280 0.0823

PHE 1280 THR 1281 0.0688

THR 1281 VAL 1282 0.0831

VAL 1282 ASN 1283 0.0786

ASN 1283 VAL 1284 0.0870

VAL 1284 ASP 1285 0.0870

ASP 1285 VAL 1286 0.0865

VAL 1286 SER 1287 0.0850

SER 1287 SER 1288 0.0867

SER 1288 LYS 1289 0.0085

LYS 1289 ALA 1290 0.0821

ALA 1290 ASP 1291 0.0785

ASP 1291 SER 1292 0.0448

SER 1292 GLU 1293 0.1062

GLU 1293 HIS 1294 0.0879

HIS 1294 THR 1295 0.0105

THR 1295 PRO 1296 0.0796

PRO 1296 VAL 1297 0.0488

VAL 1297 LEU 1298 0.0878

LEU 1298 GLU 1299 0.0856

GLU 1299 ILE 1300 0.0880

ILE 1300 LYS 1301 0.0874

LYS 1301 GLY 1302 0.0853

GLY 1302 LEU 1303 0.0874

LEU 1303 ARG 1304 0.0865

ARG 1304 ASN 1305 0.0757

ASN 1305 GLN 1306 0.0878

GLN 1306 SER 1307 0.0719

SER 1307 VAL 1308 0.0664

VAL 1308 GLY 1309 0.5146

GLY 1309 GLN 1310 0.0103

GLN 1310 MET 1311 0.0286

MET 1311 ALA 1312 0.0071

ALA 1312 PRO 1313 0.0212

PRO 1313 GLN 1314 0.0284

GLN 1314 PRO 1315 0.0079

PRO 1315 GLY 1316 0.0250

GLY 1316 ASP 1317 0.0231

ASP 1317 SER 1318 0.0161

SER 1318 SER 1319 0.0279

SER 1319 ASN 1320 0.0076

ASN 1320 ASN 1321 0.0207

ASN 1321 ASP 1322 0.0115

ASP 1322 LEU 1323 0.0278

LEU 1323 CYS 1324 0.0015

CYS 1324 PHE 1325 0.3684

PHE 1325 LYS 1326 0.0017

LYS 1326 LEU 1327 0.0011

LEU 1327 ASP 1328 0.0034

ASP 1328 TRP 1329 0.0012

TRP 1329 ALA 1330 0.0034

ALA 1330 PRO 1331 0.0021

PRO 1331 ASP 1332 0.0032

ASP 1332 ILE 1333 0.0030

ILE 1333 SER 1334 0.0017

SER 1334 SER 1335 0.0015

SER 1335 VAL 1336 0.0029

VAL 1336 LYS 1337 0.0025

LYS 1337 GLN 1338 0.0028

GLN 1338 GLU 1339 0.0031

GLU 1339 ARG 1340 0.0029

ARG 1340 LEU 1341 -0.2759

LEU 1341 LYS 1342 0.0075

LYS 1342 GLU 1343 0.0356

GLU 1343 LYS 1344 0.0325

LYS 1344 PHE 1345 0.0239

PHE 1345 GLY 1346 0.0108

GLY 1346 PHE 1347 0.0180

PHE 1347 PRO 1348 0.0258

PRO 1348 LEU 1349 0.0012

LEU 1349 ASP 1350 0.0358

ASP 1350 PRO 1351 0.0100

PRO 1351 THR 1352 0.0362

THR 1352 GLU 1353 0.0388

GLU 1353 ALA 1354 0.0309

ALA 1354 ASP 1355 0.0146

ASP 1355 ILE 1356 0.0396

ILE 1356 ILE 1357 0.0516

ILE 1357 MET 1358 0.0252

MET 1358 GLY 1359 0.0736

GLY 1359 LEU 1360 0.0695

LEU 1360 ARG 1361 0.0896

ARG 1361 GLN 1362 0.0072

GLN 1362 ALA 1363 0.0942

ALA 1363 CYS 1364 0.0777

CYS 1364 ILE 1365 0.0486

ILE 1365 HIS 1366 0.0517

HIS 1366 PHE 1367 0.0776

PHE 1367 ILE 1368 0.0928

ILE 1368 HIS 1369 0.0128

HIS 1369 ARG 1370 0.0818

ARG 1370 SER 1371 0.0657

SER 1371 LEU 1372 0.0902

LEU 1372 GLN 1373 0.0204

GLN 1373 SER 1374 0.1063

SER 1374 LEU 1375 0.0694

LEU 1375 THR 1376 0.0799

THR 1376 ALA 1377 0.1006

ALA 1377 PRO 1378 0.0940

PRO 1378 ASP 1379 0.0802

ASP 1379 ARG 1380 0.0904

ARG 1380 ASP 1381 0.1010

ASP 1381 GLN 1382 0.0850

GLN 1382 LEU 1383 0.0765

LEU 1383 ASP 1384 0.0036

ASP 1384 TRP 1385 0.0814

TRP 1385 HIS 1386 0.1006

HIS 1386 GLN 1387 0.0163

GLN 1387 LYS 1388 0.0982

LYS 1388 ARG 1389 0.0919

ARG 1389 PHE 1390 0.0878

PHE 1390 TYR 1391 0.0146

TYR 1391 ASP 1392 0.0939

ASP 1392 TRP 1393 0.0825

TRP 1393 MET 1394 0.0359

MET 1394 VAL 1395 0.0672

VAL 1395 LEU 1396 0.0667

LEU 1396 GLN 1397 0.0976

GLN 1397 ILE 1398 0.0002

ILE 1398 GLN 1399 0.0979

GLN 1399 LEU 1400 0.0621

LEU 1400 ALA 1401 0.0636

ALA 1401 GLU 1402 0.0412

GLU 1402 GLU 1403 0.0726

GLU 1403 ASP 1404 0.0943

ASP 1404 ARG 1405 0.0695

ARG 1405 LEU 1406 0.0948

LEU 1406 ALA 1407 0.0984

ALA 1407 PRO 1408 0.0605

PRO 1408 ASN 1409 0.0221

ASN 1409 SER 1410 0.0920

SER 1410 SER 1411 0.0344

SER 1411 ALA 1412 0.0827

ALA 1412 TRP 1413 0.0717

TRP 1413 LEU 1414 0.0790

LEU 1414 GLN 1415 0.0310

GLN 1415 CYS 1416 0.0972

CYS 1416 SER 1417 0.0656

SER 1417 SER 1418 0.0965

SER 1418 SER 1419 0.1038

SER 1419 ASP 1420 0.0697

ASP 1420 GLU 1421 0.0835

GLU 1421 GLN 1422 0.0928

GLN 1422 LYS 1423 0.0870

LYS 1423 LEU 1424 0.0635

LEU 1424 LEU 1425 0.0810

LEU 1425 GLU 1426 0.0933

GLU 1426 ASN 1427 0.0787

ASN 1427 VAL 1428 0.0666

VAL 1428 ARG 1429 0.0888

ARG 1429 ALA 1430 0.0896

ALA 1430 SER 1431 0.0764

SER 1431 SER 1432 0.0455

SER 1432 VAL 1433 0.0797

VAL 1433 ASN 1434 0.0869

ASN 1434 GLY 1435 0.0127

GLY 1435 GLN 1436 0.0933

GLN 1436 MET 1437 0.0795

MET 1437 VAL 1438 0.0525

VAL 1438 VAL 1439 0.0451

VAL 1439 HIS 1440 0.0817

HIS 1440 VAL 1441 0.0936

VAL 1441 GLY 1442 0.0369

GLY 1442 LYS 1443 0.0579

LYS 1443 SER 1444 0.0837

SER 1444 MET 1445 0.0949

MET 1445 LEU 1446 0.0405

LEU 1446 ALA 1447 0.0864

ALA 1447 ILE 1448 0.0182

ILE 1448 LEU 1449 0.0824

LEU 1449 ARG 1450 0.0744

ARG 1450 HIS 1451 0.0278

HIS 1451 GLU 1452 0.0841

GLU 1452 ILE 1453 -0.0494

ILE 1453 ALA 1454 0.0131

ALA 1454 PRO 1455 0.0814

PRO 1455 LEU 1456 0.0085

LEU 1456 GLU 1457 0.0799

GLU 1457 LEU 1458 0.0317

LEU 1458 MET 1459 0.0574

MET 1459 LEU 1460 0.0417

LEU 1460 GLN 1461 0.0488

GLN 1461 ASP 1462 0.0794

ASP 1462 LYS 1463 0.0327

LYS 1463 LEU 1464 0.0476

LEU 1464 LEU 1465 0.0567

LEU 1465 TYR 1466 0.0326

TYR 1466 ARG 1467 0.0573

ARG 1467 TYR 1468 0.0727

TYR 1468 TYR 1469 -0.0336

TYR 1469 THR 1470 0.0440

THR 1470 ASP 1471 0.0236

ASP 1471 ALA 1472 0.0301

ALA 1472 ILE 1473 0.0490

ILE 1473 LYS 1474 0.0302

LYS 1474 TRP 1475 0.0258

TRP 1475 ASP 1476 0.0353

ASP 1476 ARG 1477 0.0499

ARG 1477 SER 1478 0.0455

SER 1478 TYR 1479 0.0305

TYR 1479 GLN 1480 0.0447

GLN 1480 GLN 1481 0.0493

GLN 1481 ILE 1482 0.0393

ILE 1482 ASP 1483 0.0364

ASP 1483 GLN 1484 0.0456

GLN 1484 LEU 1485 -0.0135

LEU 1485 VAL 1486 0.0150

VAL 1486 LYS 1487 0.0156

LYS 1487 LEU 1488 0.0186

LEU 1488 HIS 1489 0.0190

HIS 1489 ALA 1490 0.0156

ALA 1490 HIS 1491 0.0156

HIS 1491 LYS 1492 0.0186

LYS 1492 CYS 1493 0.0197

CYS 1493 PRO 1494 0.0196

PRO 1494 THR 1495 0.0182

THR 1495 ALA 1496 0.0065

ALA 1496 LYS 1497 0.0187

LYS 1497 ILE 1498 0.0004

ILE 1498 ILE 1499 0.0096

ILE 1499 GLU 1500 0.0018

GLU 1500 ILE 1501 -0.0279

ILE 1501 GLY 1502 0.0140

GLY 1502 ALA 1503 0.0304

ALA 1503 GLY 1504 0.0169

GLY 1504 THR 1505 0.0332

THR 1505 GLY 1506 0.0149

GLY 1506 GLY 1507 0.0238

GLY 1507 CYS 1508 0.0233

CYS 1508 THR 1509 0.0111

THR 1509 ARG 1510 0.0334

ARG 1510 ALA 1511 0.0336

ALA 1511 VAL 1512 0.0178

VAL 1512 LEU 1513 0.0216

LEU 1513 ASP 1514 0.0331

ASP 1514 ALA 1515 0.0314

ALA 1515 LEU 1516 0.0138

LEU 1516 SER 1517 0.0494

SER 1517 ASN 1518 0.0183

ASN 1518 GLN 1519 0.0206

GLN 1519 GLY 1520 0.0197

GLY 1520 ILE 1521 0.0101

ILE 1521 ALA 1522 0.0196

ALA 1522 ARG 1523 0.0198

ARG 1523 CYS 1524 0.0202

CYS 1524 ALA 1525 0.0101

ALA 1525 GLN 1526 0.0122

GLN 1526 TYR 1527 0.0003

TYR 1527 ASP 1528 0.0182

ASP 1528 PHE 1529 0.0044

PHE 1529 THR 1530 0.0168

THR 1530 ASP 1531 0.0056

ASP 1531 VAL 1532 0.0185

VAL 1532 SER 1533 0.1347

SER 1533 SER 1534 0.0181

SER 1534 GLY 1535 0.0147

GLY 1535 PHE 1536 0.0310

PHE 1536 PHE 1537 -0.0000

PHE 1537 GLU 1538 0.0324

GLU 1538 ALA 1539 0.0216

ALA 1539 ALA 1540 0.0246

ALA 1540 GLN 1541 0.0067

GLN 1541 GLN 1542 0.0298

GLN 1542 LYS 1543 0.0276

LYS 1543 PHE 1544 0.0112

PHE 1544 ALA 1545 0.0154

ALA 1545 ALA 1546 0.0266

ALA 1546 PHE 1547 0.0310

PHE 1547 ASP 1548 0.0301

ASP 1548 ASP 1549 0.0004

ASP 1549 VAL 1550 0.0273

VAL 1550 ILE 1551 0.0075

ILE 1551 ARG 1552 0.0306

ARG 1552 PHE 1553 0.0074

PHE 1553 GLN 1554 0.0298

GLN 1554 LYS 1555 0.0124

LYS 1555 LEU 1556 0.0300

LEU 1556 ASP 1557 0.0162

ASP 1557 ILE 1558 0.0298

ILE 1558 GLU 1559 0.0232

GLU 1559 LYS 1560 0.0165

LYS 1560 ASP 1561 0.0035

ASP 1561 ILE 1562 0.0209

ILE 1562 GLU 1563 0.0081

GLU 1563 MET 1564 0.0231

MET 1564 GLN 1565 0.0594

GLN 1565 GLY 1566 0.0072

GLY 1566 PHE 1567 0.0318

PHE 1567 GLU 1568 0.0154

GLU 1568 CYS 1569 0.0296

CYS 1569 GLY 1570 0.0310

GLY 1570 SER 1571 0.0300

SER 1571 TYR 1572 0.0149

TYR 1572 ASP 1573 0.0319

ASP 1573 LEU 1574 0.0026

LEU 1574 VAL 1575 0.0151

VAL 1575 ILE 1576 0.0100

ILE 1576 ALA 1577 0.0087

ALA 1577 SER 1578 0.0098

SER 1578 GLN 1579 0.0086

GLN 1579 VAL 1580 0.0262

VAL 1580 LEU 1581 0.0063

LEU 1581 HIS 1582 0.0073

HIS 1582 ALA 1583 0.0414

ALA 1583 THR 1584 0.0224

THR 1584 GLY 1585 0.0409

GLY 1585 LYS 1586 0.0306

LYS 1586 MET 1587 0.0401

MET 1587 GLU 1588 0.0164

GLU 1588 HIS 1589 0.0323

HIS 1589 THR 1590 0.0388

THR 1590 MET 1591 0.0373

MET 1591 ALA 1592 0.0116

ALA 1592 ASN 1593 0.0401

ASN 1593 VAL 1594 0.0387

VAL 1594 ARG 1595 0.0240

ARG 1595 LYS 1596 0.0194

LYS 1596 LEU 1597 0.0234

LEU 1597 LEU 1598 0.0318

LEU 1598 LYS 1599 0.0063

LYS 1599 PRO 1600 0.0335

PRO 1600 GLY 1601 0.0273

GLY 1601 GLY 1602 0.0266

GLY 1602 LYS 1603 0.0043

LYS 1603 LEU 1604 0.0093

LEU 1604 LEU 1605 0.0157

LEU 1605 LEU 1606 0.0068

LEU 1606 VAL 1607 0.0071

VAL 1607 GLU 1608 0.0187

GLU 1608 THR 1609 0.0017

THR 1609 THR 1610 0.0338

THR 1610 ARG 1611 0.0003

ARG 1611 ASP 1612 0.0222

ASP 1612 GLU 1613 -0.0119

GLU 1613 MET 1614 0.0258

MET 1614 ASP 1615 0.0808

ASP 1615 LEU 1616 0.0136

LEU 1616 GLN 1617 0.0752

GLN 1617 LEU 1618 0.0291

LEU 1618 VAL 1619 0.0610

VAL 1619 PHE 1620 0.0327

PHE 1620 GLY 1621 0.0658

GLY 1621 LEU 1622 0.0719

LEU 1622 LEU 1623 0.0102

LEU 1623 PRO 1624 0.0683

PRO 1624 GLY 1625 0.0251

GLY 1625 TRP 1626 0.0639

TRP 1626 TRP 1627 0.0794

TRP 1627 LEU 1628 0.0194

LEU 1628 SER 1629 0.2154

SER 1629 SER 1630 0.0600

SER 1630 GLU 1631 0.0611

GLU 1631 GLU 1632 0.0233

GLU 1632 GLU 1633 0.0606

GLU 1633 ARG 1634 0.0612

ARG 1634 GLN 1635 0.0375

GLN 1635 MET 1636 0.0262

MET 1636 SER 1637 0.0438

SER 1637 PRO 1638 0.0139

PRO 1638 SER 1639 0.0593

SER 1639 LEU 1640 0.0468

LEU 1640 SER 1641 0.0588

SER 1641 THR 1642 0.0312

THR 1642 ASN 1643 0.0599

ASN 1643 SER 1644 0.0598

SER 1644 TRP 1645 0.1406

TRP 1645 GLU 1646 0.0297

GLU 1646 LYS 1647 0.0388

LYS 1647 VAL 1648 0.0366

VAL 1648 LEU 1649 0.0228

LEU 1649 LYS 1650 0.0325

LYS 1650 LYS 1651 0.0393

LYS 1651 THR 1652 0.0333

THR 1652 GLY 1653 0.0160

GLY 1653 PHE 1654 0.0327

PHE 1654 ASP 1655 0.0391

ASP 1655 GLY 1656 0.0005

GLY 1656 LEU 1657 0.0266

LEU 1657 ASP 1658 0.0309

ASP 1658 ILE 1659 0.0154

ILE 1659 GLU 1660 0.0027

GLU 1660 LEU 1661 0.0039

LEU 1661 ARG 1662 0.0008

ARG 1662 ASP 1663 0.0351

ASP 1663 CYS 1664 0.0341

CYS 1664 ASP 1665 0.0436

ASP 1665 SER 1666 0.0077

SER 1666 ASP 1667 0.0422

ASP 1667 GLU 1668 0.0104

GLU 1668 PHE 1669 0.0407

PHE 1669 TYR 1670 0.0055

TYR 1670 SER 1671 0.0434

SER 1671 PHE 1672 0.0046

PHE 1672 SER 1673 0.0124

SER 1673 VAL 1674 0.0082

VAL 1674 MET 1675 0.0304

MET 1675 MET 1676 0.0008

MET 1676 ALA 1677 0.0557

ALA 1677 THR 1678 0.0176

THR 1678 ALA 1679 0.0093

ALA 1679 SER 1680 0.0103

SER 1680 SER 1681 0.0200

SER 1681 THR 1682 0.0085

THR 1682 ILE 1683 0.0173

ILE 1683 ALA 1684 0.0142

ALA 1684 SER 1685 0.0183

SER 1685 SER 1686 0.0167

SER 1686 SER 1687 0.0164

SER 1687 MET 1688 0.0035

MET 1688 ALA 1689 0.0191

ALA 1689 PHE 1690 0.0066

PHE 1690 ALA 1691 0.0120

ALA 1691 ILE 1692 0.0095

ILE 1692 VAL 1693 0.1158

VAL 1693 TYR 1694 0.0032

TYR 1694 GLY 1695 0.0015

GLY 1695 GLU 1696 0.0071

GLU 1696 VAL 1697 0.0095

VAL 1697 PRO 1698 0.0012

PRO 1698 LEU 1699 0.0087

LEU 1699 PRO 1700 0.0092

PRO 1700 ASP 1701 0.0013

ASP 1701 GLN 1702 0.0091

GLN 1702 PHE 1703 0.0088

PHE 1703 LEU 1704 0.0076

LEU 1704 ASP 1705 0.0023

ASP 1705 ASP 1706 0.0098

ASP 1706 MET 1707 0.0094

MET 1707 LYS 1708 0.0038

LYS 1708 THR 1709 0.0150

THR 1709 ALA 1710 0.0093

ALA 1710 ILE 1711 0.0108

ILE 1711 SER 1712 0.0015

SER 1712 SER 1713 0.0105

SER 1713 SER 1714 0.0101

SER 1714 ALA 1715 0.0097

ALA 1715 VAL 1716 0.0030

VAL 1716 SER 1717 0.0088

SER 1717 ASP 1718 0.0075

ASP 1718 PRO 1719 0.0019

PRO 1719 VAL 1720 0.0100

VAL 1720 VAL 1721 0.0023

VAL 1721 GLY 1722 0.0068

GLY 1722 HIS 1723 0.0012

HIS 1723 LEU 1724 0.0097

LEU 1724 ASP 1725 0.0380

ASP 1725 SER 1726 0.0031

SER 1726 ILE 1727 0.0065

ILE 1727 ASP 1728 0.0067

ASP 1728 ALA 1729 0.0124

ALA 1729 THR 1730 0.0072

THR 1730 GLY 1731 0.0058

GLY 1731 LYS 1732 0.0114

LYS 1732 PHE 1733 0.0110

PHE 1733 CYS 1734 0.0029

CYS 1734 ILE 1735 0.0091

ILE 1735 PHE 1736 0.0010

PHE 1736 ILE 1737 0.0090

ILE 1737 GLU 1738 0.0006

GLU 1738 ASP 1739 0.0075

ASP 1739 PRO 1740 0.0082

PRO 1740 GLU 1741 -0.0028

GLU 1741 THR 1742 0.0113

THR 1742 ASP 1743 0.0110

ASP 1743 ILE 1744 0.0107

ILE 1744 LEU 1745 0.0109

LEU 1745 SER 1746 0.0023

SER 1746 SER 1747 0.0094

SER 1747 PRO 1748 0.0058

PRO 1748 ASP 1749 0.0109

ASP 1749 GLU 1750 0.0103

GLU 1750 LYS 1751 0.0039

LYS 1751 SER 1752 0.0102

SER 1752 TYR 1753 0.0111

TYR 1753 ALA 1754 0.0081

ALA 1754 SER 1755 0.0053

SER 1755 ILE 1756 0.0112

ILE 1756 GLN 1757 0.0373

GLN 1757 LYS 1758 0.0046

LYS 1758 LEU 1759 0.0093

LEU 1759 VAL 1760 0.0107

VAL 1760 THR 1761 0.0093

THR 1761 ARG 1762 0.0051

ARG 1762 CYS 1763 0.0097

CYS 1763 LYS 1764 0.0038

LYS 1764 GLY 1765 0.0080

GLY 1765 LEU 1766 0.0041

LEU 1766 ILE 1767 0.0099

ILE 1767 TRP 1768 0.0003

TRP 1768 VAL 1769 0.0099

VAL 1769 SER 1770 0.0015

SER 1770 ARG 1771 0.0076

ARG 1771 GLY 1772 0.0066

GLY 1772 GLY 1773 0.0545

GLY 1773 ALA 1774 0.0062

ALA 1774 MET 1775 0.0101

MET 1775 HIS 1776 0.0036

HIS 1776 GLY 1777 0.0066

GLY 1777 THR 1778 0.0097

THR 1778 ARG 1779 0.0095

ARG 1779 PRO 1780 0.0090

PRO 1780 ASN 1781 0.0102

ASN 1781 SER 1782 0.0002

SER 1782 SER 1783 0.0099

SER 1783 LEU 1784 0.0086

LEU 1784 LYS 1785 0.0021

LYS 1785 THR 1786 0.0080

THR 1786 GLY 1787 0.0063

GLY 1787 LEU 1788 0.0099

LEU 1788 LEU 1789 0.0004

LEU 1789 ARG 1790 0.0087

ARG 1790 THR 1791 0.0078

THR 1791 LEU 1792 0.0052

LEU 1792 ARG 1793 0.0033

ARG 1793 LEU 1794 0.0080

LEU 1794 GLU 1795 0.0083

GLU 1795 TYR 1796 0.0022

TYR 1796 THR 1797 0.0046

THR 1797 GLU 1798 0.0038

GLU 1798 LYS 1799 0.0073

LYS 1799 ARG 1800 0.0088

ARG 1800 PHE 1801 0.0013

PHE 1801 ILE 1802 0.0086

ILE 1802 SER 1803 0.0031

SER 1803 LEU 1804 0.0084

LEU 1804 ASP 1805 -0.0313

ASP 1805 LEU 1806 0.0116

LEU 1806 ASP 1807 0.0077

ASP 1807 SER 1808 0.0033

SER 1808 ALA 1809 0.0115

ALA 1809 ARG 1810 0.0033

ARG 1810 PRO 1811 0.0113

PRO 1811 GLN 1812 0.0113

GLN 1812 TRP 1813 0.0013

TRP 1813 ASN 1814 0.0090

ASN 1814 HIS 1815 0.0015

HIS 1815 ASP 1816 0.0104

ASP 1816 SER 1817 0.0106

SER 1817 ILE 1818 0.0020

ILE 1818 THR 1819 0.0096

THR 1819 THR 1820 0.0074

THR 1820 ILE 1821 0.0217

ILE 1821 ASN 1822 0.0009

ASN 1822 GLU 1823 0.0078

GLU 1823 VAL 1824 0.0072

VAL 1824 LEU 1825 0.0038

LEU 1825 CYS 1826 0.0045

CYS 1826 GLY 1827 0.0067

GLY 1827 ALA 1828 0.0081

ALA 1828 LEU 1829 0.0006

LEU 1829 ALA 1830 0.0072

ALA 1830 GLN 1831 0.0080

GLN 1831 ASN 1832 0.0018

ASN 1832 ALA 1833 0.0080

ALA 1833 ASP 1834 0.0073

ASP 1834 SER 1835 0.0012

SER 1835 SER 1836 0.0061

SER 1836 ILE 1837 -0.0681

ILE 1837 LYS 1838 0.0054

LYS 1838 ASP 1839 0.0027

ASP 1839 SER 1840 0.0048

SER 1840 GLU 1841 0.0022

GLU 1841 PHE 1842 0.0053

PHE 1842 ALA 1843 0.0032

ALA 1843 GLU 1844 0.0054

GLU 1844 GLN 1845 0.0030

GLN 1845 ASP 1846 0.0051

ASP 1846 GLY 1847 0.0004

GLY 1847 GLN 1848 0.0053

GLN 1848 LEU 1849 0.0052

LEU 1849 PHE 1850 0.0032

PHE 1850 VAL 1851 0.0053

VAL 1851 PRO 1852 0.0024

PRO 1852 ARG 1853 0.1881

ARG 1853 ILE 1854 0.0062

ILE 1854 SER 1855 0.0033

SER 1855 CYS 1856 0.0037

CYS 1856 ASP 1857 0.0032

ASP 1857 ILE 1858 0.0054

ILE 1858 ALA 1859 0.0031

ALA 1859 ARG 1860 0.0085

ARG 1860 ASN 1861 0.0083

ASN 1861 GLU 1862 0.0026

GLU 1862 ASP 1863 0.0067

ASP 1863 LEU 1864 0.0070

LEU 1864 SER 1865 0.0086

SER 1865 SER 1866 0.0013

SER 1866 ASP 1867 0.0076

ASP 1867 SER 1868 0.0083

SER 1868 ASN 1869 0.4172

ASN 1869 SER 1870 0.1201

SER 1870 PRO 1871 0.0872

PRO 1871 ALA 1872 0.0476

ALA 1872 GLN 1873 0.1205

GLN 1873 MET 1874 0.0417

MET 1874 GLU 1875 0.1199

GLU 1875 PRO 1876 0.0546

PRO 1876 PHE 1877 0.0807

PHE 1877 HIS 1878 0.1191

HIS 1878 GLN 1879 0.0326

GLN 1879 PRO 1880 0.1203

PRO 1880 GLY 1881 0.1006

GLY 1881 LYS 1882 0.1195

LYS 1882 LEU 1883 0.0853

LEU 1883 LEU 1884 0.1179

LEU 1884 GLN 1885 0.0666

GLN 1885 MET 1886 0.0925

MET 1886 GLY 1887 0.0885

GLY 1887 ILE 1888 0.0917

ILE 1888 LYS 1889 0.0122

LYS 1889 THR 1890 0.0886

THR 1890 PRO 1891 0.0141

PRO 1891 GLY 1892 0.0877

GLY 1892 LEU 1893 0.0738

LEU 1893 ILE 1894 0.0662

ILE 1894 ASP 1895 0.0420

ASP 1895 THR 1896 0.0786

THR 1896 LEU 1897 0.0572

LEU 1897 GLN 1898 0.0672

GLN 1898 PHE 1899 0.0951

PHE 1899 SER 1900 0.0648

SER 1900 LYS 1901 0.1197

LYS 1901 THR 1902 0.1183

THR 1902 ASP 1903 0.1341

ASP 1903 ALA 1904 0.0682

ALA 1904 THR 1905 0.1276

THR 1905 ASP 1906 0.1231

ASP 1906 ASN 1907 0.0767

ASN 1907 LEU 1908 0.0316

LEU 1908 PRO 1909 0.1018

PRO 1909 ASN 1910 0.0512

ASN 1910 ASP 1911 0.0788

ASP 1911 TYR 1912 0.1058

TYR 1912 ILE 1913 0.1352

ILE 1913 GLU 1914 0.0683

GLU 1914 ILE 1915 0.1270

ILE 1915 GLU 1916 0.1014

GLU 1916 PRO 1917 0.1376

PRO 1917 LYS 1918 0.1137

LYS 1918 ALA 1919 0.1107

ALA 1919 PHE 1920 0.1184

PHE 1920 GLY 1921 0.0879

GLY 1921 LEU 1922 0.0871

LEU 1922 ASN 1923 0.1063

ASN 1923 PHE 1924 0.1168

PHE 1924 ARG 1925 0.1059

ARG 1925 ASP 1926 0.0533

ASP 1926 VAL 1927 0.1111

VAL 1927 MET 1928 0.1177

MET 1928 VAL 1929 0.0796

VAL 1929 ALA 1930 0.0725

ALA 1930 MET 1931 0.1185

MET 1931 GLY 1932 0.1166

GLY 1932 GLN 1933 0.1551

GLN 1933 LEU 1934 0.1037

LEU 1934 GLU 1935 0.1049

GLU 1935 GLU 1936 0.1190

GLU 1936 SER 1937 0.0639

SER 1937 ILE 1938 0.0843

ILE 1938 MET 1939 0.1157

MET 1939 GLY 1940 0.0928

GLY 1940 PHE 1941 0.0166

PHE 1941 GLU 1942 0.1007

GLU 1942 CYS 1943 0.1157

CYS 1943 ALA 1944 0.1034

ALA 1944 GLY 1945 0.0964

GLY 1945 VAL 1946 0.1200

VAL 1946 VAL 1947 0.1200

VAL 1947 ARG 1948 0.0324

ARG 1948 ARG 1949 0.2041

ARG 1949 VAL 1950 0.0641

VAL 1950 GLY 1951 0.1304

GLY 1951 PRO 1952 0.1069

PRO 1952 SER 1953 0.0604

SER 1953 SER 1954 0.1298

SER 1954 ALA 1955 0.1274

ALA 1955 GLY 1956 0.0324

GLY 1956 HIS 1957 0.1191

HIS 1957 ASN 1958 0.1306

ASN 1958 ILE 1959 0.0266

ILE 1959 LYS 1960 0.0895

LYS 1960 VAL 1961 0.0241

VAL 1961 GLY 1962 0.1308

GLY 1962 ASP 1963 0.0537

ASP 1963 ARG 1964 0.1315

ARG 1964 VAL 1965 0.1310

VAL 1965 CYS 1966 0.1179

CYS 1966 ALA 1967 0.1072

ALA 1967 LEU 1968 0.1175

LEU 1968 LEU 1969 0.0142

LEU 1969 GLY 1970 0.0981

GLY 1970 GLY 1971 0.0786

GLY 1971 GLN 1972 0.0643

GLN 1972 TRP 1973 0.1116

TRP 1973 THR 1974 0.1069

THR 1974 ASN 1975 0.1184

ASN 1975 THR 1976 0.0976

THR 1976 VAL 1977 0.0648

VAL 1977 ARG 1978 0.1079

ARG 1978 VAL 1979 0.0311

VAL 1979 HIS 1980 0.0642

HIS 1980 TRP 1981 0.1003

TRP 1981 HIS 1982 0.0646

HIS 1982 SER 1983 0.0933

SER 1983 VAL 1984 0.1134

VAL 1984 ALA 1985 0.0540

ALA 1985 PRO 1986 0.1135

PRO 1986 ILE 1987 0.1143

ILE 1987 PRO 1988 0.0760

PRO 1988 GLN 1989 0.0917

GLN 1989 ALA 1990 0.1109

ALA 1990 MET 1991 0.0963

MET 1991 ASP 1992 0.0173

ASP 1992 TRP 1993 0.0603

TRP 1993 GLU 1994 0.1140

GLU 1994 THR 1995 0.0060

THR 1995 ALA 1996 0.1139

ALA 1996 ALA 1997 0.1031

ALA 1997 SER 1998 0.0882

SER 1998 ILE 1999 0.0431

ILE 1999 PRO 2000 0.0952

PRO 2000 ILE 2001 0.0853

ILE 2001 VAL 2002 0.0779

VAL 2002 PHE 2003 0.0177

PHE 2003 VAL 2004 0.0980

VAL 2004 THR 2005 0.0896

THR 2005 ALA 2006 0.0392

ALA 2006 TYR 2007 0.0599

TYR 2007 ILE 2008 0.0902

ILE 2008 SER 2009 0.0997

SER 2009 LEU 2010 0.0260

LEU 2010 VAL 2011 0.0681

VAL 2011 LYS 2012 0.0912

LYS 2012 ILE 2013 -0.0217

ILE 2013 ALA 2014 0.0554

ALA 2014 ARG 2015 0.0185

ARG 2015 MET 2016 0.0636

MET 2016 GLN 2017 0.0055

GLN 2017 ALA 2018 0.0510

ALA 2018 GLY 2019 0.0659

GLY 2019 GLU 2020 0.0245

GLU 2020 THR 2021 0.0296

THR 2021 VAL 2022 0.0090

VAL 2022 LEU 2023 0.0139

LEU 2023 ILE 2024 0.0368

ILE 2024 HIS 2025 0.0046

HIS 2025 ALA 2026 0.0419

ALA 2026 ALA 2027 0.0203

ALA 2027 SER 2028 0.0525

SER 2028 GLY 2029 0.0881

GLY 2029 GLY 2030 0.0749

GLY 2030 VAL 2031 0.0687

VAL 2031 GLY 2032 0.0637

GLY 2032 GLN 2033 0.0656

GLN 2033 ALA 2034 0.0742

ALA 2034 ALA 2035 0.0677

ALA 2035 ILE 2036 0.0599

ILE 2036 ILE 2037 0.0710

ILE 2037 LEU 2038 0.0729

LEU 2038 ALA 2039 0.0685

ALA 2039 LYS 2040 0.0564

LYS 2040 HIS 2041 0.0736

HIS 2041 VAL 2042 0.0722

VAL 2042 GLY 2043 0.0632

GLY 2043 ALA 2044 0.0555

ALA 2044 GLU 2045 0.0801

GLU 2045 ILE 2046 0.0052

ILE 2046 PHE 2047 0.0454

PHE 2047 ALA 2048 0.0126

ALA 2048 THR 2049 0.0125

THR 2049 VAL 2050 0.0435

VAL 2050 GLY 2051 0.0125

GLY 2051 THR 2052 0.0816

THR 2052 ASP 2053 0.0481

ASP 2053 GLU 2054 0.0806

GLU 2054 LYS 2055 0.0759

LYS 2055 ARG 2056 0.0338

ARG 2056 ASP 2057 0.0762

ASP 2057 LEU 2058 0.0818

LEU 2058 LEU 2059 0.0484

LEU 2059 ILE 2060 0.0516

ILE 2060 LYS 2061 0.0293

LYS 2061 GLU 2062 0.0763

GLU 2062 TYR 2063 0.0591

TYR 2063 LYS 2064 0.0495

LYS 2064 ILE 2065 0.0721

ILE 2065 PRO 2066 0.0718

PRO 2066 ASP 2067 0.0312

ASP 2067 ASP 2068 0.0696

ASP 2068 HIS 2069 0.0759

HIS 2069 ILE 2070 0.0051

ILE 2070 PHE 2071 0.0398

PHE 2071 SER 2072 0.0009

SER 2072 SER 2073 0.0652

SER 2073 ARG 2074 0.0268

ARG 2074 ASN 2075 0.0635

ASN 2075 ALA 2076 0.0446

ALA 2076 LEU 2077 -0.0579

LEU 2077 PHE 2078 0.0365

PHE 2078 ALA 2079 0.0432

ALA 2079 LYS 2080 0.0459

LYS 2080 SER 2081 0.0481

SER 2081 ILE 2082 0.0408

ILE 2082 ARG 2083 0.0412

ARG 2083 GLN 2084 0.0483

GLN 2084 ARG 2085 0.0462

ARG 2085 THR 2086 0.0412

THR 2086 ASN 2087 0.0427

ASN 2087 GLY 2088 0.0356

GLY 2088 LYS 2089 0.0484

LYS 2089 GLY 2090 0.0137

GLY 2090 VAL 2091 0.0520

VAL 2091 ASP 2092 0.0421

ASP 2092 VAL 2093 0.0296

VAL 2093 VAL 2094 0.0013

VAL 2094 LEU 2095 0.0189

LEU 2095 ASN 2096 0.0120

ASN 2096 CYS 2097 0.0032

CYS 2097 LEU 2098 0.0290

LEU 2098 ALA 2099 0.0293

ALA 2099 GLY 2100 0.0343

GLY 2100 GLY 2101 0.0285

GLY 2101 LEU 2102 0.0315

LEU 2102 LEU 2103 0.0243

LEU 2103 GLN 2104 0.0270

GLN 2104 GLU 2105 0.0335

GLU 2105 SER 2106 0.0300

SER 2106 PHE 2107 0.0228

PHE 2107 ASP 2108 0.0313

ASP 2108 CYS 2109 0.0773

CYS 2109 LEU 2110 0.0223

LEU 2110 ALA 2111 0.0009

ALA 2111 ASP 2112 0.0157

ASP 2112 PHE 2113 0.0250

PHE 2113 GLY 2114 0.0078

GLY 2114 ARG 2115 0.0095

ARG 2115 PHE 2116 0.0043

PHE 2116 ILE 2117 0.0115

ILE 2117 GLU 2118 0.0047

GLU 2118 ILE 2119 0.0107

ILE 2119 GLY 2120 0.0144

GLY 2120 LYS 2121 0.0183

LYS 2121 ARG 2122 0.0218

ARG 2122 ASP 2123 0.0123

ASP 2123 ILE 2124 0.0250

ILE 2124 GLU 2125 -0.0140

GLU 2125 LEU 2126 0.0114

LEU 2126 ASN 2127 0.0012

ASN 2127 HIS 2128 0.0100

HIS 2128 CYS 2129 0.0007

CYS 2129 LEU 2130 0.0071

LEU 2130 ASN 2131 0.0033

ASN 2131 MET 2132 0.0047

MET 2132 GLY 2133 0.0067

GLY 2133 MET 2134 0.0111

MET 2134 PHE 2135 0.0098

PHE 2135 ALA 2136 0.0023

ALA 2136 ARG 2137 0.0114

ARG 2137 SER 2138 0.0113

SER 2138 ALA 2139 0.0009

ALA 2139 THR 2140 0.0068

THR 2140 PHE 2141 0.0632

PHE 2141 THR 2142 0.0550

THR 2142 ALA 2143 0.0014

ALA 2143 VAL 2144 0.0739

VAL 2144 ASP 2145 0.0125

ASP 2145 LEU 2146 0.0771

LEU 2146 ILE 2147 0.0279

ILE 2147 ALA 2148 0.0601

ALA 2148 ILE 2149 0.0401

ILE 2149 GLY 2150 0.0446

GLY 2150 ARG 2151 0.0674

ARG 2151 ASP 2152 0.0278

ASP 2152 ARG 2153 0.0377

ARG 2153 SER 2154 0.0664

SER 2154 TYR 2155 0.0231

TYR 2155 MET 2156 0.0719

MET 2156 PHE 2157 -0.1930

PHE 2157 ALA 2158 0.0805

ALA 2158 GLU 2159 0.0178

GLU 2159 ALA 2160 0.0896

ALA 2160 LEU 2161 0.0622

LEU 2161 PRO 2162 0.0661

PRO 2162 LYS 2163 0.0301

LYS 2163 ILE 2164 0.0761

ILE 2164 MET 2165 0.0865

MET 2165 THR 2166 0.0121

THR 2166 LEU 2167 0.0811

LEU 2167 LEU 2168 0.0544

LEU 2168 GLN 2169 0.0872

GLN 2169 GLU 2170 0.0049

GLU 2170 LYS 2171 0.0873

LYS 2171 ALA 2172 0.0734

ALA 2172 ILE 2173 0.0906

ILE 2173 ARG 2174 0.0537

ARG 2174 PRO 2175 0.0007

PRO 2175 VAL 2176 0.0799

VAL 2176 THR 2177 0.0960

THR 2177 PRO 2178 0.0389

PRO 2178 ILE 2179 0.0644

ILE 2179 SER 2180 0.0197

SER 2180 ILE 2181 0.0717

ILE 2181 TYR 2182 0.0007

TYR 2182 LYS 2183 0.0619

LYS 2183 ILE 2184 0.0767

ILE 2184 GLY 2185 0.0361

GLY 2185 ASP 2186 0.0887

ASP 2186 ILE 2187 0.0970

ILE 2187 GLU 2188 0.0761

GLU 2188 THR 2189 0.1762

THR 2189 ALA 2190 0.0431

ALA 2190 PHE 2191 0.0956

PHE 2191 ARG 2192 0.1027

ARG 2192 LEU 2193 0.0226

LEU 2193 MET 2194 0.0886

MET 2194 GLN 2195 0.0761

GLN 2195 ALA 2196 0.0946

ALA 2196 GLY 2197 0.0158

GLY 2197 LYS 2198 0.0997

LYS 2198 HIS 2199 0.0947

HIS 2199 MET 2200 0.0101

MET 2200 GLY 2201 0.0952

GLY 2201 LYS 2202 0.0528

LYS 2202 ILE 2203 0.0102

ILE 2203 VAL 2204 0.0983

VAL 2204 ILE 2205 0.2490

ILE 2205 THR 2206 0.0862

THR 2206 ALA 2207 0.0181

ALA 2207 PRO 2208 0.0920

PRO 2208 GLU 2209 0.0256

GLU 2209 ASP 2210 0.0828

ASP 2210 ALA 2211 0.0909

ALA 2211 MET 2212 0.0534

MET 2212 VAL 2213 0.0996

VAL 2213 PRO 2214 0.0719

PRO 2214 VAL 2215 0.0785

VAL 2215 ILE 2216 0.0713

ILE 2216 THR 2217 0.0531

THR 2217 ARG 2218 0.1006

ARG 2218 PRO 2219 0.0179

PRO 2219 PRO 2220 0.1007

PRO 2220 LYS 2221 -0.3031

LYS 2221 LEU 2222 0.0029

LEU 2222 GLN 2223 0.0003

GLN 2223 LEU 2224 0.0027

LEU 2224 ARG 2225 0.0000

ARG 2225 PRO 2226 0.0030

PRO 2226 ASP 2227 0.0012

ASP 2227 ALA 2228 0.0028

ALA 2228 SER 2229 0.0031

SER 2229 TYR 2230 0.0001

TYR 2230 LEU 2231 0.0036

LEU 2231 ILE 2232 0.0008

ILE 2232 VAL 2233 0.0033

VAL 2233 GLY 2234 0.0019

GLY 2234 GLY 2235 0.0033

GLY 2235 LEU 2236 0.0036

LEU 2236 GLY 2237 -0.0592

GLY 2237 GLY 2238 0.0023

GLY 2238 ILE 2239 0.0010

ILE 2239 GLY 2240 0.0034

GLY 2240 ARG 2241 0.0036

ARG 2241 SER 2242 0.0006

SER 2242 LEU 2243 0.0030

LEU 2243 CYS 2244 0.0029

CYS 2244 LYS 2245 0.0029

LYS 2245 ASN 2246 0.0008

ASN 2246 PHE 2247 0.0035

PHE 2247 VAL 2248 0.0033

VAL 2248 GLU 2249 0.0016

GLU 2249 ASN 2250 0.0021

ASN 2250 GLY 2251 0.0031

GLY 2251 ALA 2252 0.0009

ALA 2252 ARG 2253 -0.0487

ARG 2253 SER 2254 0.0011

SER 2254 LEU 2255 0.0036

LEU 2255 VAL 2256 0.0015

VAL 2256 LEU 2257 0.0034

LEU 2257 LEU 2258 0.0022

LEU 2258 SER 2259 0.0032

SER 2259 ARG 2260 0.0014

ARG 2260 ASN 2261 0.0034

ASN 2261 ALA 2262 0.0036

ALA 2262 ASN 2263 0.0021

ASN 2263 VAL 2264 0.0022

VAL 2264 SER 2265 0.0032

SER 2265 GLN 2266 0.0036

GLN 2266 GLN 2267 0.0013

GLN 2267 SER 2268 0.0027

SER 2268 GLY 2269 0.0800

GLY 2269 GLU 2270 0.0007

GLU 2270 PHE 2271 0.0033

PHE 2271 LEU 2272 0.0027

LEU 2272 ASP 2273 0.0016

ASP 2273 GLU 2274 0.0025

GLU 2274 LEU 2275 0.0024

LEU 2275 ARG 2276 0.0037

ARG 2276 SER 2277 0.0000

SER 2277 THR 2278 0.0037

THR 2278 GLY 2279 0.0029

GLY 2279 CYS 2280 0.0011

CYS 2280 ILE 2281 0.0010

ILE 2281 VAL 2282 0.0030

VAL 2282 GLY 2283 0.0002

GLY 2283 VAL 2284 0.0033

VAL 2284 VAL 2285 0.1919

VAL 2285 ASP 2286 0.0039

ASP 2286 CYS 2287 0.0049

CYS 2287 ASP 2288 0.0051

ASP 2288 ILE 2289 0.0023

ILE 2289 SER 2290 0.0050

SER 2290 SER 2291 0.0019

SER 2291 LYS 2292 0.0051

LYS 2292 THR 2293 0.0019

THR 2293 GLN 2294 0.0055

GLN 2294 VAL 2295 0.0004

VAL 2295 GLU 2296 0.0050

GLU 2296 ALA 2297 0.0027

ALA 2297 THR 2298 0.0030

THR 2298 MET 2299 0.0029

MET 2299 LEU 2300 0.0027

LEU 2300 ARG 2301 -0.0195

ARG 2301 LEU 2302 0.0013

LEU 2302 LYS 2303 0.0051

LYS 2303 LYS 2304 0.0013

LYS 2304 ASP 2305 0.0051

ASP 2305 MET 2306 0.0002

MET 2306 LEU 2307 0.0025

LEU 2307 PRO 2308 0.0036

PRO 2308 ILE 2309 0.0037

ILE 2309 ARG 2310 0.0003

ARG 2310 GLY 2311 0.0041

GLY 2311 ILE 2312 0.0048

ILE 2312 VAL 2313 0.0045

VAL 2313 HIS 2314 0.0048

HIS 2314 ALA 2315 0.0050

ALA 2315 GLY 2316 0.0026

GLY 2316 MET 2317 0.1463

MET 2317 VAL 2318 0.0159

VAL 2318 LEU 2319 0.0070

LEU 2319 GLN 2320 0.0151

GLN 2320 ASP 2321 0.0034

ASP 2321 SER 2322 0.0114

SER 2322 VAL 2323 0.0012

VAL 2323 PHE 2324 0.0155

PHE 2324 GLU 2325 0.0148

GLU 2325 ARG 2326 0.0040

ARG 2326 MET 2327 0.0105

MET 2327 SER 2328 0.0077

SER 2328 LEU 2329 0.0147

LEU 2329 ASP 2330 0.0038

ASP 2330 ASP 2331 0.0126

ASP 2331 TYR 2332 0.0108

TYR 2332 ASN 2333 -0.0170

ASN 2333 THR 2334 0.0121

THR 2334 ALA 2335 0.0045

ALA 2335 ILE 2336 0.0130

ILE 2336 ARG 2337 0.0031

ARG 2337 PRO 2338 0.0145

PRO 2338 LYS 2339 0.0016

LYS 2339 VAL 2340 0.0142

VAL 2340 GLN 2341 0.0022

GLN 2341 GLY 2342 0.0129

GLY 2342 SER 2343 0.0062

SER 2343 TRP 2344 0.0139

TRP 2344 ASN 2345 0.0006

ASN 2345 LEU 2346 0.0137

LEU 2346 HIS 2347 0.0075

HIS 2347 SER 2348 0.0081

SER 2348 GLY 2349 0.0076

GLY 2349 LEU 2350 0.0056

LEU 2350 SER 2351 0.0055

SER 2351 ASP 2352 0.0037

ASP 2352 CYS 2353 0.0064

CYS 2353 ASP 2354 0.0036

ASP 2354 LEU 2355 0.0055

LEU 2355 ASP 2356 0.0043

ASP 2356 PHE 2357 0.0057

PHE 2357 PHE 2358 0.0068

PHE 2358 ILE 2359 0.0054

ILE 2359 MET 2360 0.0066

MET 2360 LEU 2361 0.0063

LEU 2361 SER 2362 0.0043

SER 2362 SER 2363 0.0046

SER 2363 LEU 2364 0.0005

LEU 2364 ALA 2365 0.1385

ALA 2365 GLY 2366 0.0131

GLY 2366 VAL 2367 0.0052

VAL 2367 SER 2368 0.0079

SER 2368 GLY 2369 0.0129

GLY 2369 SER 2370 0.0128

SER 2370 ALA 2371 0.0123

ALA 2371 SER 2372 0.0054

SER 2372 GLN 2373 0.0088

GLN 2373 ALA 2374 0.0132

ALA 2374 ASN 2375 0.0005

ASN 2375 TYR 2376 0.0131

TYR 2376 THR 2377 0.0048

THR 2377 ALA 2378 0.0123

ALA 2378 GLY 2379 0.0028

GLY 2379 GLY 2380 0.0111

GLY 2380 ALA 2381 0.0233

ALA 2381 TYR 2382 0.0026

TYR 2382 GLN 2383 0.0077

GLN 2383 ASP 2384 0.0021

ASP 2384 ALA 2385 0.0087

ALA 2385 LEU 2386 0.0006

LEU 2386 ALA 2387 0.0082

ALA 2387 LYS 2388 0.0050

LYS 2388 TYR 2389 0.0052

TYR 2389 ARG 2390 0.0044

ARG 2390 ARG 2391 0.0051

ARG 2391 ALA 2392 0.0079

ALA 2392 GLN 2393 0.0006

GLN 2393 GLY 2394 0.0089

GLY 2394 LEU 2395 0.0061

LEU 2395 SER 2396 0.0087

SER 2396 ALA 2397 -0.0295

ALA 2397 VAL 2398 0.0034

VAL 2398 SER 2399 0.0043

SER 2399 ILE 2400 0.0043

ILE 2400 ASP 2401 0.0037

ASP 2401 LEU 2402 0.0037

LEU 2402 GLY 2403 0.0034

GLY 2403 MET 2404 0.0034

MET 2404 VAL 2405 0.0023

VAL 2405 GLN 2406 0.0044

GLN 2406 SER 2407 0.0010

SER 2407 VAL 2408 0.0027

VAL 2408 GLY 2409 0.0044

GLY 2409 TYR 2410 0.0041

TYR 2410 VAL 2411 0.0013

VAL 2411 ALA 2412 0.0034

ALA 2412 GLU 2413 0.0597

GLU 2413 THR 2414 0.0090

THR 2414 LYS 2415 0.0093

LYS 2415 GLY 2416 0.0013

GLY 2416 VAL 2417 0.0100

VAL 2417 ALA 2418 0.0080

ALA 2418 GLU 2419 0.0072

GLU 2419 ARG 2420 0.0104

ARG 2420 LEU 2421 0.0099

LEU 2421 VAL 2422 0.0068

VAL 2422 ARG 2423 0.0086

ARG 2423 MET 2424 0.0107

MET 2424 GLY 2425 0.0082

GLY 2425 TYR 2426 0.0048

TYR 2426 SER 2427 0.0107

SER 2427 PRO 2428 0.0024

PRO 2428 ILE 2429 0.1151

ILE 2429 SER 2430 0.0046

SER 2430 GLU 2431 0.0022

GLU 2431 MET 2432 0.0039

MET 2432 GLU 2433 0.0034

GLU 2433 VAL 2434 0.0025

VAL 2434 LEU 2435 0.0051

LEU 2435 LYS 2436 0.0011

LYS 2436 ILE 2437 0.0055

ILE 2437 VAL 2438 0.0014

VAL 2438 GLU 2439 0.0056

GLU 2439 HIS 2440 0.0011

HIS 2440 ALA 2441 0.0047

ALA 2441 ILE 2442 0.0039

ILE 2442 THR 2443 0.0028

THR 2443 ASN 2444 0.0026

ASN 2444 PRO 2445 0.1362

PRO 2445 PRO 2446 0.0006

PRO 2446 PRO 2447 0.0042

PRO 2447 GLU 2448 0.0032

GLU 2448 ALA 2449 0.0039

ALA 2449 SER 2450 0.0012

SER 2450 SER 2451 0.0041

SER 2451 ALA 2452 0.0008

ALA 2452 GLN 2453 0.0039

GLN 2453 ILE 2454 0.0041

ILE 2454 ILE 2455 0.0029

ILE 2455 THR 2456 0.0043

THR 2456 GLY 2457 0.0039

GLY 2457 ILE 2458 0.0001

ILE 2458 SER 2459 0.0030

SER 2459 THR 2460 0.0018

THR 2460 LYS 2461 -0.0519

LYS 2461 PRO 2462 0.0014

PRO 2462 GLY 2463 0.0055

GLY 2463 ARG 2464 0.0053

ARG 2464 HIS 2465 0.0010

HIS 2465 TRP 2466 0.0045

TRP 2466 THR 2467 0.0042

THR 2467 GLU 2468 0.0027

GLU 2468 SER 2469 0.0016

SER 2469 SER 2470 0.0053

SER 2470 TRP 2471 0.0033

TRP 2471 LEU 2472 0.0031

LEU 2472 GLN 2473 0.0035

GLN 2473 ASP 2474 0.0030

ASP 2474 ALA 2475 0.0050

ALA 2475 ARG 2476 0.0024

ARG 2476 PHE 2477 0.0304

PHE 2477 ALA 2478 0.0024

ALA 2478 THR 2479 0.0048

THR 2479 LEU 2480 0.0046

LEU 2480 ARG 2481 0.0022

ARG 2481 GLU 2482 0.0033

GLU 2482 ARG 2483 0.0045

ARG 2483 ALA 2484 0.0040

ALA 2484 ARG 2485 0.0019

ARG 2485 ASP 2486 0.0047

ASP 2486 VAL 2487 0.0049

VAL 2487 LYS 2488 0.0024

LYS 2488 GLU 2489 0.0033

GLU 2489 LEU 2490 0.0046

LEU 2490 SER 2491 0.0037

SER 2491 ASN 2492 0.0017

ASN 2492 SER 2493 0.0888

SER 2493 GLN 2494 0.0140

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** sdgklnrdh ***

CA strain for 22101813491974862

--- normal mode 22 ---

Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *