Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *

CA strain for 22101813491974862

--- normal mode 15 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
ASN 989 LYS 990 0.0031

LYS 990 ALA 991 0.0022

ALA 991 HIS 992 0.0017

HIS 992 ARG 993 0.0016

ARG 993 GLN 994 0.0017

GLN 994 ARG 995 0.0029

ARG 995 VAL 996 0.0030

VAL 996 HIS 997 0.0033

HIS 997 PRO 998 0.0018

PRO 998 PRO 999 0.0029

PRO 999 HIS 1000 0.0024

HIS 1000 ASP 1001 0.0032

ASP 1001 LEU 1002 0.0001

LEU 1002 LEU 1003 0.0031

LEU 1003 GLY 1004 0.0013

GLY 1004 SER 1005 0.0011

SER 1005 LEU 1006 0.0034

LEU 1006 ILE 1007 0.0048

ILE 1007 VAL 1008 0.0035

VAL 1008 GLY 1009 0.0040

GLY 1009 ARG 1010 0.0002

ARG 1010 ASP 1011 0.0028

ASP 1011 LEU 1012 0.0047

LEU 1012 ARG 1013 0.0003

ARG 1013 GLU 1014 0.0049

GLU 1014 PRO 1015 0.0019

PRO 1015 THR 1016 0.0043

THR 1016 TRP 1017 0.0027

TRP 1017 ARG 1018 0.0035

ARG 1018 HIS 1019 0.0042

HIS 1019 PHE 1020 0.0035

PHE 1020 ILE 1021 -0.0690

ILE 1021 ARG 1022 0.0034

ARG 1022 VAL 1023 0.0043

VAL 1023 GLN 1024 0.0016

GLN 1024 ASP 1025 0.0053

ASP 1025 ILE 1026 0.0051

ILE 1026 PRO 1027 0.0047

PRO 1027 TRP 1028 0.0049

TRP 1028 ILE 1029 0.0004

ILE 1029 ARG 1030 0.0051

ARG 1030 ASP 1031 0.0054

ASP 1031 HIS 1032 0.0006

HIS 1032 VAL 1033 0.0033

VAL 1033 VAL 1034 0.0009

VAL 1034 GLN 1035 0.0039

GLN 1035 SER 1036 0.0028

SER 1036 ALA 1037 0.0708

ALA 1037 LEU 1038 0.0039

LEU 1038 VAL 1039 0.0027

VAL 1039 TYR 1040 0.0052

TYR 1040 PRO 1041 0.0051

PRO 1041 GLY 1042 0.0010

GLY 1042 ALA 1043 0.0039

ALA 1043 GLY 1044 0.0039

GLY 1044 PHE 1045 0.0018

PHE 1045 ILE 1046 0.0053

ILE 1046 CYS 1047 0.0005

CYS 1047 MET 1048 0.0053

MET 1048 ALA 1049 0.0022

ALA 1049 MET 1050 0.0037

MET 1050 GLU 1051 0.0020

GLU 1051 ALA 1052 0.0034

ALA 1052 MET 1053 -0.0016

MET 1053 VAL 1054 0.0032

VAL 1054 GLN 1055 0.0050

GLN 1055 LEU 1056 0.0023

LEU 1056 HIS 1057 0.0068

HIS 1057 GLU 1058 0.0010

GLU 1058 LEU 1059 0.0070

LEU 1059 ARG 1060 0.0017

ARG 1060 ASP 1061 0.0067

ASP 1061 SER 1062 0.0044

SER 1062 GLN 1063 0.0041

GLN 1063 SER 1064 0.0064

SER 1064 ARG 1065 0.0017

ARG 1065 LYS 1066 0.0064

LYS 1066 VAL 1067 0.0067

VAL 1067 ALA 1068 0.0045

ALA 1068 GLY 1069 -0.0071

GLY 1069 TYR 1070 0.0050

TYR 1070 ARG 1071 0.0008

ARG 1071 LEU 1072 0.0054

LEU 1072 ALA 1073 0.0006

ALA 1073 GLU 1074 0.0046

GLU 1074 VAL 1075 0.0018

VAL 1075 ASP 1076 0.0057

ASP 1076 ILE 1077 0.0028

ILE 1077 LEU 1078 0.0051

LEU 1078 ARG 1079 0.0026

ARG 1079 ALA 1080 0.0012

ALA 1080 MET 1081 0.0024

MET 1081 LEU 1082 0.0039

LEU 1082 ILE 1083 0.0003

ILE 1083 PRO 1084 0.0041

PRO 1084 ASP 1085 -0.0707

ASP 1085 THR 1086 0.0034

THR 1086 SER 1087 0.0023

SER 1087 GLU 1088 0.0032

GLU 1088 GLY 1089 0.0023

GLY 1089 LEU 1090 0.0011

LEU 1090 GLU 1091 0.0050

GLU 1091 ALA 1092 0.0027

ALA 1092 HIS 1093 0.0044

HIS 1093 ILE 1094 0.0036

ILE 1094 SER 1095 0.0040

SER 1095 LEU 1096 0.0043

LEU 1096 ARG 1097 0.0025

ARG 1097 PRO 1098 0.0040

PRO 1098 CYS 1099 0.0004

CYS 1099 SER 1100 0.0033

SER 1100 THR 1101 0.0050

THR 1101 LYS 1102 0.0017

LYS 1102 LEU 1103 0.0071

LEU 1103 LEU 1104 0.0056

LEU 1104 LEU 1105 0.0023

LEU 1105 THR 1106 0.0066

THR 1106 ASN 1107 0.0004

ASN 1107 GLU 1108 0.0039

GLU 1108 TRP 1109 0.0071

TRP 1109 TYR 1110 0.0047

TYR 1110 ASP 1111 0.0068

ASP 1111 PHE 1112 0.0026

PHE 1112 CYS 1113 0.0069

CYS 1113 VAL 1114 0.0033

VAL 1114 SER 1115 0.0067

SER 1115 SER 1116 0.0033

SER 1116 VAL 1117 -0.0026

VAL 1117 GLY 1118 0.0060

GLY 1118 ASP 1119 0.0048

ASP 1119 ASP 1120 0.0032

ASP 1120 ASP 1121 0.0060

ASP 1121 LYS 1122 0.0013

LYS 1122 PHE 1123 0.0060

PHE 1123 VAL 1124 0.0054

VAL 1124 ASP 1125 0.0054

ASP 1125 HIS 1126 0.0059

HIS 1126 CYS 1127 0.0056

CYS 1127 ARG 1128 0.0045

ARG 1128 GLY 1129 0.0060

GLY 1129 ARG 1130 0.0061

ARG 1130 ILE 1131 0.0029

ILE 1131 THR 1132 0.0059

THR 1132 ILE 1133 -0.0230

ILE 1133 GLU 1134 0.0066

GLU 1134 PHE 1135 0.0070

PHE 1135 ASP 1136 0.0075

ASP 1136 THR 1137 0.0019

THR 1137 SER 1138 0.0075

SER 1138 GLY 1139 0.0021

GLY 1139 SER 1140 0.0071

SER 1140 ALA 1141 0.0073

ALA 1141 ASP 1142 0.0065

ASP 1142 THR 1143 0.0036

THR 1143 PRO 1144 0.0060

PRO 1144 ARG 1145 0.0064

ARG 1145 THR 1146 0.0070

THR 1146 SER 1147 0.0027

SER 1147 LEU 1148 0.0072

LEU 1148 ARG 1149 -0.0494

ARG 1149 GLU 1150 0.0023

GLU 1150 ARG 1151 0.0077

ARG 1151 SER 1152 0.0008

SER 1152 ARG 1153 0.0075

ARG 1153 SER 1154 0.0078

SER 1154 THR 1155 0.0049

THR 1155 GLY 1156 0.0047

GLY 1156 LEU 1157 0.0006

LEU 1157 MET 1158 0.0073

MET 1158 ARG 1159 0.0041

ARG 1159 SER 1160 0.0051

SER 1160 VAL 1161 0.0078

VAL 1161 ASP 1162 0.0044

ASP 1162 PRO 1163 0.0060

PRO 1163 SER 1164 0.0041

SER 1164 ASN 1165 -0.0100

ASN 1165 LEU 1166 0.0010

LEU 1166 TYR 1167 0.0040

TYR 1167 SER 1168 0.0037

SER 1168 PHE 1169 0.0018

PHE 1169 LEU 1170 0.0024

LEU 1170 ARG 1171 0.0038

ARG 1171 ALA 1172 0.0039

ALA 1172 GLN 1173 0.0008

GLN 1173 GLY 1174 0.0041

GLY 1174 ILE 1175 0.0040

ILE 1175 TYR 1176 0.0015

TYR 1176 HIS 1177 0.0033

HIS 1177 GLY 1178 0.0020

GLY 1178 PRO 1179 0.0013

PRO 1179 ILE 1180 0.0033

ILE 1180 PHE 1181 0.0085

PHE 1181 GLN 1182 0.0037

GLN 1182 ASN 1183 0.0052

ASN 1183 LEU 1184 0.0052

LEU 1184 LYS 1185 0.0021

LYS 1185 THR 1186 0.0046

THR 1186 ILE 1187 0.0020

ILE 1187 SER 1188 0.0049

SER 1188 SER 1189 0.0017

SER 1189 ARG 1190 0.0033

ARG 1190 LYS 1191 0.0015

LYS 1191 ASP 1192 0.0033

ASP 1192 HIS 1193 0.0034

HIS 1193 SER 1194 0.0014

SER 1194 GLU 1195 0.0032

GLU 1195 SER 1196 0.0040

SER 1196 SER 1197 0.0440

SER 1197 PHE 1198 0.0038

PHE 1198 VAL 1199 0.0021

VAL 1199 VAL 1200 0.0048

VAL 1200 ALA 1201 0.0038

ALA 1201 ASN 1202 0.0019

ASN 1202 THR 1203 0.0035

THR 1203 ALA 1204 0.0028

ALA 1204 SER 1205 0.0027

SER 1205 VAL 1206 0.0035

VAL 1206 MET 1207 0.0046

MET 1207 PRO 1208 0.0033

PRO 1208 ASN 1209 0.0019

ASN 1209 GLY 1210 0.0041

GLY 1210 PHE 1211 0.0031

PHE 1211 GLN 1212 0.0007

GLN 1212 SER 1213 -0.0033

SER 1213 PRO 1214 0.0057

PRO 1214 HIS 1215 0.0017

HIS 1215 VAL 1216 0.0038

VAL 1216 ILE 1217 0.0057

ILE 1217 HIS 1218 0.0052

HIS 1218 PRO 1219 0.0034

PRO 1219 THR 1220 0.0037

THR 1220 THR 1221 0.0060

THR 1221 LEU 1222 -0.0000

LEU 1222 ASP 1223 0.0058

ASP 1223 SER 1224 0.0041

SER 1224 ILE 1225 0.0029

ILE 1225 PHE 1226 0.0030

PHE 1226 GLN 1227 0.0042

GLN 1227 GLY 1228 0.0057

GLY 1228 ALA 1229 0.0142

ALA 1229 TYR 1230 0.0047

TYR 1230 THR 1231 0.0035

THR 1231 ALA 1232 0.0031

ALA 1232 LEU 1233 0.0059

LEU 1233 PRO 1234 0.0049

PRO 1234 GLY 1235 0.0004

GLY 1235 ALA 1236 0.0060

ALA 1236 GLY 1237 0.0046

GLY 1237 LEU 1238 0.0028

LEU 1238 ASP 1239 0.0039

ASP 1239 GLN 1240 0.0030

GLN 1240 ASN 1241 0.0053

ASN 1241 THR 1242 0.0054

THR 1242 ALA 1243 0.0060

ALA 1243 MET 1244 0.0037

MET 1244 ILE 1245 0.0369

ILE 1245 PRO 1246 0.0061

PRO 1246 ARG 1247 0.0010

ARG 1247 SER 1248 0.0057

SER 1248 ILE 1249 0.0063

ILE 1249 GLN 1250 0.0033

GLN 1250 GLU 1251 0.0041

GLU 1251 LEU 1252 0.0002

LEU 1252 TYR 1253 0.0053

TYR 1253 LEU 1254 0.0003

LEU 1254 SER 1255 0.0054

SER 1255 SER 1256 0.0039

SER 1256 ALA 1257 0.0043

ALA 1257 LEU 1258 0.0061

LEU 1258 THR 1259 0.0009

THR 1259 SER 1260 0.0062

SER 1260 ASP 1261 0.0313

ASP 1261 VAL 1262 0.0041

VAL 1262 GLY 1263 0.0061

GLY 1263 GLN 1264 0.0031

GLN 1264 CYS 1265 0.0057

CYS 1265 LEU 1266 0.0002

LEU 1266 VAL 1267 0.0049

VAL 1267 SER 1268 0.0018

SER 1268 ASP 1269 0.0039

ASP 1269 THR 1270 0.0042

THR 1270 SER 1271 0.0022

SER 1271 LEU 1272 0.0053

LEU 1272 ILE 1273 -0.0001

ILE 1273 ARG 1274 0.0061

ARG 1274 TYR 1275 0.0048

TYR 1275 ASP 1276 0.0055

ASP 1276 GLY 1277 0.0762

GLY 1277 GLN 1278 0.0064

GLN 1278 SER 1279 0.0075

SER 1279 PHE 1280 0.0066

PHE 1280 THR 1281 0.0069

THR 1281 VAL 1282 0.0045

VAL 1282 ASN 1283 0.0074

ASN 1283 VAL 1284 0.0020

VAL 1284 ASP 1285 0.0062

ASP 1285 VAL 1286 0.0024

VAL 1286 SER 1287 0.0047

SER 1287 SER 1288 0.0015

SER 1288 LYS 1289 0.0036

LYS 1289 ALA 1290 0.0063

ALA 1290 ASP 1291 0.0023

ASP 1291 SER 1292 0.0074

SER 1292 GLU 1293 -0.0091

GLU 1293 HIS 1294 0.0059

HIS 1294 THR 1295 0.0029

THR 1295 PRO 1296 0.0056

PRO 1296 VAL 1297 0.0057

VAL 1297 LEU 1298 0.0048

LEU 1298 GLU 1299 0.0024

GLU 1299 ILE 1300 0.0052

ILE 1300 LYS 1301 0.0018

LYS 1301 GLY 1302 0.0056

GLY 1302 LEU 1303 0.0028

LEU 1303 ARG 1304 0.0055

ARG 1304 ASN 1305 0.0033

ASN 1305 GLN 1306 0.0054

GLN 1306 SER 1307 0.0051

SER 1307 VAL 1308 0.0059

VAL 1308 GLY 1309 0.3291

GLY 1309 GLN 1310 0.0297

GLN 1310 MET 1311 0.0355

MET 1311 ALA 1312 0.0379

ALA 1312 PRO 1313 0.0133

PRO 1313 GLN 1314 0.0323

GLN 1314 PRO 1315 0.0381

PRO 1315 GLY 1316 0.0068

GLY 1316 ASP 1317 0.0313

ASP 1317 SER 1318 0.0366

SER 1318 SER 1319 0.0044

SER 1319 ASN 1320 0.0265

ASN 1320 ASN 1321 0.0379

ASN 1321 ASP 1322 0.0272

ASP 1322 LEU 1323 0.0131

LEU 1323 CYS 1324 0.0248

CYS 1324 PHE 1325 -0.1758

PHE 1325 LYS 1326 0.0043

LYS 1326 LEU 1327 0.0030

LEU 1327 ASP 1328 0.0033

ASP 1328 TRP 1329 0.0037

TRP 1329 ALA 1330 0.0042

ALA 1330 PRO 1331 0.0041

PRO 1331 ASP 1332 0.0016

ASP 1332 ILE 1333 0.0037

ILE 1333 SER 1334 0.0010

SER 1334 SER 1335 0.0043

SER 1335 VAL 1336 0.0002

VAL 1336 LYS 1337 0.0042

LYS 1337 GLN 1338 0.0021

GLN 1338 GLU 1339 0.0032

GLU 1339 ARG 1340 0.0043

ARG 1340 LEU 1341 0.0855

LEU 1341 LYS 1342 0.1066

LYS 1342 GLU 1343 0.0493

GLU 1343 LYS 1344 0.0828

LYS 1344 PHE 1345 0.0156

PHE 1345 GLY 1346 0.1055

GLY 1346 PHE 1347 0.1020

PHE 1347 PRO 1348 0.0792

PRO 1348 LEU 1349 0.0833

LEU 1349 ASP 1350 0.0985

ASP 1350 PRO 1351 0.1052

PRO 1351 THR 1352 0.0408

THR 1352 GLU 1353 0.0759

GLU 1353 ALA 1354 0.0937

ALA 1354 ASP 1355 0.0990

ASP 1355 ILE 1356 0.0200

ILE 1356 ILE 1357 0.1174

ILE 1357 MET 1358 0.1300

MET 1358 GLY 1359 0.0508

GLY 1359 LEU 1360 0.1044

LEU 1360 ARG 1361 0.1251

ARG 1361 GLN 1362 0.1153

GLN 1362 ALA 1363 0.0454

ALA 1363 CYS 1364 0.1274

CYS 1364 ILE 1365 0.1295

ILE 1365 HIS 1366 0.0751

HIS 1366 PHE 1367 0.0789

PHE 1367 ILE 1368 0.1269

ILE 1368 HIS 1369 0.1294

HIS 1369 ARG 1370 0.0422

ARG 1370 SER 1371 0.1109

SER 1371 LEU 1372 0.1238

LEU 1372 GLN 1373 0.0886

GLN 1373 SER 1374 0.0463

SER 1374 LEU 1375 0.1296

LEU 1375 THR 1376 0.0684

THR 1376 ALA 1377 0.1306

ALA 1377 PRO 1378 0.0712

PRO 1378 ASP 1379 0.0952

ASP 1379 ARG 1380 0.0584

ARG 1380 ASP 1381 0.0954

ASP 1381 GLN 1382 0.1201

GLN 1382 LEU 1383 0.0206

LEU 1383 ASP 1384 0.1237

ASP 1384 TRP 1385 0.0574

TRP 1385 HIS 1386 0.0834

HIS 1386 GLN 1387 0.1145

GLN 1387 LYS 1388 0.1265

LYS 1388 ARG 1389 0.0432

ARG 1389 PHE 1390 0.1333

PHE 1390 TYR 1391 0.1145

TYR 1391 ASP 1392 0.0703

ASP 1392 TRP 1393 0.0758

TRP 1393 MET 1394 0.1127

MET 1394 VAL 1395 0.1332

VAL 1395 LEU 1396 0.0114

LEU 1396 GLN 1397 0.1282

GLN 1397 ILE 1398 0.1144

ILE 1398 GLN 1399 0.0988

GLN 1399 LEU 1400 0.0464

LEU 1400 ALA 1401 0.1272

ALA 1401 GLU 1402 0.1319

GLU 1402 GLU 1403 0.0343

GLU 1403 ASP 1404 0.1084

ASP 1404 ARG 1405 0.1056

ARG 1405 LEU 1406 0.1072

LEU 1406 ALA 1407 0.0876

ALA 1407 PRO 1408 0.1050

PRO 1408 ASN 1409 0.0634

ASN 1409 SER 1410 0.0636

SER 1410 SER 1411 0.0998

SER 1411 ALA 1412 0.1258

ALA 1412 TRP 1413 0.1001

TRP 1413 LEU 1414 0.0606

LEU 1414 GLN 1415 0.1272

GLN 1415 CYS 1416 0.1268

CYS 1416 SER 1417 0.0769

SER 1417 SER 1418 0.0623

SER 1418 SER 1419 0.1149

SER 1419 ASP 1420 0.0217

ASP 1420 GLU 1421 0.1191

GLU 1421 GLN 1422 0.1023

GLN 1422 LYS 1423 0.0486

LYS 1423 LEU 1424 0.1017

LEU 1424 LEU 1425 0.0716

LEU 1425 GLU 1426 0.1341

GLU 1426 ASN 1427 0.0015

ASN 1427 VAL 1428 0.1341

VAL 1428 ARG 1429 0.0657

ARG 1429 ALA 1430 0.1069

ALA 1430 SER 1431 0.0257

SER 1431 SER 1432 0.1314

SER 1432 VAL 1433 0.0837

VAL 1433 ASN 1434 0.1304

ASN 1434 GLY 1435 0.1198

GLY 1435 GLN 1436 0.0533

GLN 1436 MET 1437 0.1257

MET 1437 VAL 1438 0.1227

VAL 1438 VAL 1439 0.0851

VAL 1439 HIS 1440 0.0679

HIS 1440 VAL 1441 0.1258

VAL 1441 GLY 1442 0.1213

GLY 1442 LYS 1443 0.0544

LYS 1443 SER 1444 0.0835

SER 1444 MET 1445 0.1023

MET 1445 LEU 1446 0.0644

LEU 1446 ALA 1447 0.0694

ALA 1447 ILE 1448 0.0936

ILE 1448 LEU 1449 0.1252

LEU 1449 ARG 1450 0.0027

ARG 1450 HIS 1451 0.1240

HIS 1451 GLU 1452 0.1086

GLU 1452 ILE 1453 -0.0062

ILE 1453 ALA 1454 0.0982

ALA 1454 PRO 1455 0.0068

PRO 1455 LEU 1456 0.1203

LEU 1456 GLU 1457 0.0694

GLU 1457 LEU 1458 0.1158

LEU 1458 MET 1459 0.0181

MET 1459 LEU 1460 0.1177

LEU 1460 GLN 1461 0.1052

GLN 1461 ASP 1462 0.1030

ASP 1462 LYS 1463 0.0840

LYS 1463 LEU 1464 0.1016

LEU 1464 LEU 1465 0.1187

LEU 1465 TYR 1466 0.1107

TYR 1466 ARG 1467 0.1001

ARG 1467 TYR 1468 0.1179

TYR 1468 TYR 1469 0.0355

TYR 1469 THR 1470 0.0741

THR 1470 ASP 1471 0.0916

ASP 1471 ALA 1472 0.0934

ALA 1472 ILE 1473 0.0290

ILE 1473 LYS 1474 0.0475

LYS 1474 TRP 1475 0.0802

TRP 1475 ASP 1476 0.0694

ASP 1476 ARG 1477 0.0256

ARG 1477 SER 1478 0.0886

SER 1478 TYR 1479 0.0853

TYR 1479 GLN 1480 0.0266

GLN 1480 GLN 1481 0.0732

GLN 1481 ILE 1482 0.0644

ILE 1482 ASP 1483 0.0916

ASP 1483 GLN 1484 0.0023

GLN 1484 LEU 1485 0.1033

LEU 1485 VAL 1486 0.0296

VAL 1486 LYS 1487 0.0207

LYS 1487 LEU 1488 0.0139

LEU 1488 HIS 1489 0.0295

HIS 1489 ALA 1490 0.0322

ALA 1490 HIS 1491 0.0056

HIS 1491 LYS 1492 0.0281

LYS 1492 CYS 1493 0.0212

CYS 1493 PRO 1494 0.0289

PRO 1494 THR 1495 0.0296

THR 1495 ALA 1496 0.0240

ALA 1496 LYS 1497 0.0110

LYS 1497 ILE 1498 0.0197

ILE 1498 ILE 1499 0.0070

ILE 1499 GLU 1500 0.0194

GLU 1500 ILE 1501 0.0277

ILE 1501 GLY 1502 0.0217

GLY 1502 ALA 1503 0.0481

ALA 1503 GLY 1504 0.0113

GLY 1504 THR 1505 0.0556

THR 1505 GLY 1506 0.0031

GLY 1506 GLY 1507 0.0490

GLY 1507 CYS 1508 0.0219

CYS 1508 THR 1509 0.0556

THR 1509 ARG 1510 0.0518

ARG 1510 ALA 1511 0.0230

ALA 1511 VAL 1512 0.0523

VAL 1512 LEU 1513 0.0555

LEU 1513 ASP 1514 0.0432

ASP 1514 ALA 1515 0.0291

ALA 1515 LEU 1516 0.0556

LEU 1516 SER 1517 -0.0076

SER 1517 ASN 1518 0.0063

ASN 1518 GLN 1519 0.0234

GLN 1519 GLY 1520 0.0134

GLY 1520 ILE 1521 0.0197

ILE 1521 ALA 1522 0.0204

ALA 1522 ARG 1523 0.0159

ARG 1523 CYS 1524 0.0174

CYS 1524 ALA 1525 0.0240

ALA 1525 GLN 1526 0.0006

GLN 1526 TYR 1527 0.0132

TYR 1527 ASP 1528 0.0072

ASP 1528 PHE 1529 0.0113

PHE 1529 THR 1530 0.0121

THR 1530 ASP 1531 0.0050

ASP 1531 VAL 1532 0.0094

VAL 1532 SER 1533 0.0792

SER 1533 SER 1534 0.0579

SER 1534 GLY 1535 0.0450

GLY 1535 PHE 1536 0.0181

PHE 1536 PHE 1537 0.0471

PHE 1537 GLU 1538 0.0482

GLU 1538 ALA 1539 0.0549

ALA 1539 ALA 1540 0.0095

ALA 1540 GLN 1541 0.0575

GLN 1541 GLN 1542 0.0554

GLN 1542 LYS 1543 0.0381

LYS 1543 PHE 1544 0.0235

PHE 1544 ALA 1545 0.0579

ALA 1545 ALA 1546 0.0065

ALA 1546 PHE 1547 0.0539

PHE 1547 ASP 1548 0.0345

ASP 1548 ASP 1549 -0.0107

ASP 1549 VAL 1550 0.0627

VAL 1550 ILE 1551 0.0169

ILE 1551 ARG 1552 0.0372

ARG 1552 PHE 1553 0.0141

PHE 1553 GLN 1554 0.0542

GLN 1554 LYS 1555 0.0391

LYS 1555 LEU 1556 0.0574

LEU 1556 ASP 1557 0.0521

ASP 1557 ILE 1558 0.0294

ILE 1558 GLU 1559 0.0447

GLU 1559 LYS 1560 0.0641

LYS 1560 ASP 1561 0.0393

ASP 1561 ILE 1562 0.0395

ILE 1562 GLU 1563 0.0652

GLU 1563 MET 1564 0.0009

MET 1564 GLN 1565 0.1001

GLN 1565 GLY 1566 0.0503

GLY 1566 PHE 1567 0.0214

PHE 1567 GLU 1568 0.0188

GLU 1568 CYS 1569 0.0543

CYS 1569 GLY 1570 0.0089

GLY 1570 SER 1571 0.0717

SER 1571 TYR 1572 0.0723

TYR 1572 ASP 1573 0.0252

ASP 1573 LEU 1574 0.0555

LEU 1574 VAL 1575 0.0216

VAL 1575 ILE 1576 0.0606

ILE 1576 ALA 1577 0.0392

ALA 1577 SER 1578 0.0653

SER 1578 GLN 1579 0.0426

GLN 1579 VAL 1580 0.0598

VAL 1580 LEU 1581 -0.0192

LEU 1581 HIS 1582 0.0774

HIS 1582 ALA 1583 0.0087

ALA 1583 THR 1584 0.0816

THR 1584 GLY 1585 0.0773

GLY 1585 LYS 1586 0.0200

LYS 1586 MET 1587 0.0247

MET 1587 GLU 1588 0.0575

GLU 1588 HIS 1589 0.0462

HIS 1589 THR 1590 0.0822

THR 1590 MET 1591 0.0008

MET 1591 ALA 1592 0.0819

ALA 1592 ASN 1593 0.0540

ASN 1593 VAL 1594 0.0621

VAL 1594 ARG 1595 0.0274

ARG 1595 LYS 1596 0.0690

LYS 1596 LEU 1597 0.1576

LEU 1597 LEU 1598 0.0039

LEU 1598 LYS 1599 0.0369

LYS 1599 PRO 1600 0.0299

PRO 1600 GLY 1601 0.0610

GLY 1601 GLY 1602 0.0265

GLY 1602 LYS 1603 0.0748

LYS 1603 LEU 1604 0.0351

LEU 1604 LEU 1605 0.0746

LEU 1605 LEU 1606 0.0528

LEU 1606 VAL 1607 0.0662

VAL 1607 GLU 1608 0.0636

GLU 1608 THR 1609 0.0719

THR 1609 THR 1610 0.0378

THR 1610 ARG 1611 0.0718

ARG 1611 ASP 1612 0.0067

ASP 1612 GLU 1613 0.3348

GLU 1613 MET 1614 0.0465

MET 1614 ASP 1615 0.0934

ASP 1615 LEU 1616 0.1157

LEU 1616 GLN 1617 0.1043

GLN 1617 LEU 1618 0.0583

LEU 1618 VAL 1619 0.1054

VAL 1619 PHE 1620 0.1157

PHE 1620 GLY 1621 0.1134

GLY 1621 LEU 1622 0.0067

LEU 1622 LEU 1623 0.1158

LEU 1623 PRO 1624 0.1145

PRO 1624 GLY 1625 0.0552

GLY 1625 TRP 1626 0.0692

TRP 1626 TRP 1627 0.1131

TRP 1627 LEU 1628 0.1158

LEU 1628 SER 1629 -0.0538

SER 1629 SER 1630 0.1087

SER 1630 GLU 1631 0.0042

GLU 1631 GLU 1632 0.1029

GLU 1632 GLU 1633 0.0659

GLU 1633 ARG 1634 0.0576

ARG 1634 GLN 1635 0.0465

GLN 1635 MET 1636 0.1055

MET 1636 SER 1637 0.1017

SER 1637 PRO 1638 0.1071

PRO 1638 SER 1639 0.0164

SER 1639 LEU 1640 0.0273

LEU 1640 SER 1641 0.0227

SER 1641 THR 1642 0.0604

THR 1642 ASN 1643 0.0864

ASN 1643 SER 1644 0.0347

SER 1644 TRP 1645 0.1632

TRP 1645 GLU 1646 0.0100

GLU 1646 LYS 1647 0.0629

LYS 1647 VAL 1648 0.0256

VAL 1648 LEU 1649 0.0514

LEU 1649 LYS 1650 0.0398

LYS 1650 LYS 1651 0.0342

LYS 1651 THR 1652 0.0549

THR 1652 GLY 1653 0.0320

GLY 1653 PHE 1654 0.0557

PHE 1654 ASP 1655 0.0077

ASP 1655 GLY 1656 0.0648

GLY 1656 LEU 1657 0.0700

LEU 1657 ASP 1658 0.0393

ASP 1658 ILE 1659 0.0665

ILE 1659 GLU 1660 0.0529

GLU 1660 LEU 1661 0.1118

LEU 1661 ARG 1662 0.0765

ARG 1662 ASP 1663 0.0645

ASP 1663 CYS 1664 0.0556

CYS 1664 ASP 1665 0.0226

ASP 1665 SER 1666 0.0812

SER 1666 ASP 1667 0.0916

ASP 1667 GLU 1668 0.0497

GLU 1668 PHE 1669 0.0690

PHE 1669 TYR 1670 0.0930

TYR 1670 SER 1671 0.0285

SER 1671 PHE 1672 0.0928

PHE 1672 SER 1673 0.0524

SER 1673 VAL 1674 0.0922

VAL 1674 MET 1675 0.0852

MET 1675 MET 1676 0.0841

MET 1676 ALA 1677 0.3260

ALA 1677 THR 1678 0.0019

THR 1678 ALA 1679 0.0032

ALA 1679 SER 1680 0.0040

SER 1680 SER 1681 0.0044

SER 1681 THR 1682 0.0013

THR 1682 ILE 1683 0.0082

ILE 1683 ALA 1684 0.0009

ALA 1684 SER 1685 0.0073

SER 1685 SER 1686 0.0078

SER 1686 SER 1687 0.0043

SER 1687 MET 1688 0.0068

MET 1688 ALA 1689 0.0085

ALA 1689 PHE 1690 0.0024

PHE 1690 ALA 1691 0.0079

ALA 1691 ILE 1692 0.0025

ILE 1692 VAL 1693 -0.0457

VAL 1693 TYR 1694 0.0033

TYR 1694 GLY 1695 0.0048

GLY 1695 GLU 1696 0.0039

GLU 1696 VAL 1697 0.0011

VAL 1697 PRO 1698 0.0044

PRO 1698 LEU 1699 0.0047

LEU 1699 PRO 1700 0.0003

PRO 1700 ASP 1701 0.0049

ASP 1701 GLN 1702 0.0042

GLN 1702 PHE 1703 0.0020

PHE 1703 LEU 1704 0.0032

LEU 1704 ASP 1705 0.0037

ASP 1705 ASP 1706 0.0051

ASP 1706 MET 1707 0.0001

MET 1707 LYS 1708 0.0049

LYS 1708 THR 1709 0.0296

THR 1709 ALA 1710 0.0039

ALA 1710 ILE 1711 0.0005

ILE 1711 SER 1712 0.0043

SER 1712 SER 1713 0.0038

SER 1713 SER 1714 0.0020

SER 1714 ALA 1715 0.0022

ALA 1715 VAL 1716 0.0038

VAL 1716 SER 1717 0.0042

SER 1717 ASP 1718 0.0018

ASP 1718 PRO 1719 0.0041

PRO 1719 VAL 1720 0.0044

VAL 1720 VAL 1721 0.0025

VAL 1721 GLY 1722 0.0041

GLY 1722 HIS 1723 0.0043

HIS 1723 LEU 1724 0.0019

LEU 1724 ASP 1725 0.0375

ASP 1725 SER 1726 0.0045

SER 1726 ILE 1727 0.0054

ILE 1727 ASP 1728 0.0030

ASP 1728 ALA 1729 0.0043

ALA 1729 THR 1730 0.0034

THR 1730 GLY 1731 0.0056

GLY 1731 LYS 1732 0.0026

LYS 1732 PHE 1733 0.0058

PHE 1733 CYS 1734 0.0048

CYS 1734 ILE 1735 0.0043

ILE 1735 PHE 1736 0.0056

PHE 1736 ILE 1737 0.0031

ILE 1737 GLU 1738 0.0056

GLU 1738 ASP 1739 0.0026

ASP 1739 PRO 1740 0.0054

PRO 1740 GLU 1741 -0.0340

GLU 1741 THR 1742 0.0090

THR 1742 ASP 1743 0.0002

ASP 1743 ILE 1744 0.0107

ILE 1744 LEU 1745 0.0001

LEU 1745 SER 1746 0.0108

SER 1746 SER 1747 0.0086

SER 1747 PRO 1748 0.0104

PRO 1748 ASP 1749 0.0075

ASP 1749 GLU 1750 0.0102

GLU 1750 LYS 1751 0.0059

LYS 1751 SER 1752 0.0104

SER 1752 TYR 1753 0.0002

TYR 1753 ALA 1754 0.0108

ALA 1754 SER 1755 0.0070

SER 1755 ILE 1756 0.0057

ILE 1756 GLN 1757 0.0098

GLN 1757 LYS 1758 0.0067

LYS 1758 LEU 1759 0.0075

LEU 1759 VAL 1760 0.0027

VAL 1760 THR 1761 0.0069

THR 1761 ARG 1762 0.0045

ARG 1762 CYS 1763 0.0075

CYS 1763 LYS 1764 0.0082

LYS 1764 GLY 1765 0.0092

GLY 1765 LEU 1766 0.0072

LEU 1766 ILE 1767 0.0072

ILE 1767 TRP 1768 0.0093

TRP 1768 VAL 1769 0.0044

VAL 1769 SER 1770 0.0092

SER 1770 ARG 1771 0.0079

ARG 1771 GLY 1772 0.0068

GLY 1772 GLY 1773 -0.0064

GLY 1773 ALA 1774 0.0108

ALA 1774 MET 1775 0.0159

MET 1775 HIS 1776 0.0150

HIS 1776 GLY 1777 0.0164

GLY 1777 THR 1778 0.0036

THR 1778 ARG 1779 0.0161

ARG 1779 PRO 1780 0.0032

PRO 1780 ASN 1781 0.0144

ASN 1781 SER 1782 0.0149

SER 1782 SER 1783 0.0009

SER 1783 LEU 1784 0.0159

LEU 1784 LYS 1785 0.0146

LYS 1785 THR 1786 0.0108

THR 1786 GLY 1787 0.0062

GLY 1787 LEU 1788 0.0146

LEU 1788 LEU 1789 0.0223

LEU 1789 ARG 1790 0.0034

ARG 1790 THR 1791 0.0103

THR 1791 LEU 1792 0.0077

LEU 1792 ARG 1793 0.0124

ARG 1793 LEU 1794 0.0014

LEU 1794 GLU 1795 0.0123

GLU 1795 TYR 1796 0.0080

TYR 1796 THR 1797 0.0117

THR 1797 GLU 1798 0.0075

GLU 1798 LYS 1799 0.0049

LYS 1799 ARG 1800 0.0108

ARG 1800 PHE 1801 0.0129

PHE 1801 ILE 1802 0.0102

ILE 1802 SER 1803 0.0123

SER 1803 LEU 1804 0.0050

LEU 1804 ASP 1805 0.0405

ASP 1805 LEU 1806 0.0002

LEU 1806 ASP 1807 0.0059

ASP 1807 SER 1808 0.0065

SER 1808 ALA 1809 0.0033

ALA 1809 ARG 1810 0.0034

ARG 1810 PRO 1811 0.0045

PRO 1811 GLN 1812 0.0051

GLN 1812 TRP 1813 0.0045

TRP 1813 ASN 1814 0.0052

ASN 1814 HIS 1815 0.0062

HIS 1815 ASP 1816 0.0035

ASP 1816 SER 1817 0.0029

SER 1817 ILE 1818 0.0061

ILE 1818 THR 1819 0.0067

THR 1819 THR 1820 0.0011

THR 1820 ILE 1821 0.0214

ILE 1821 ASN 1822 0.0018

ASN 1822 GLU 1823 0.0022

GLU 1823 VAL 1824 0.0013

VAL 1824 LEU 1825 0.0033

LEU 1825 CYS 1826 0.0001

CYS 1826 GLY 1827 0.0034

GLY 1827 ALA 1828 0.0012

ALA 1828 LEU 1829 0.0028

LEU 1829 ALA 1830 0.0005

ALA 1830 GLN 1831 0.0033

GLN 1831 ASN 1832 0.0030

ASN 1832 ALA 1833 0.0028

ALA 1833 ASP 1834 0.0028

ASP 1834 SER 1835 0.0032

SER 1835 SER 1836 0.0017

SER 1836 ILE 1837 -0.0135

ILE 1837 LYS 1838 0.0048

LYS 1838 ASP 1839 0.0060

ASP 1839 SER 1840 0.0058

SER 1840 GLU 1841 0.0059

GLU 1841 PHE 1842 0.0010

PHE 1842 ALA 1843 0.0052

ALA 1843 GLU 1844 0.0003

GLU 1844 GLN 1845 0.0057

GLN 1845 ASP 1846 0.0008

ASP 1846 GLY 1847 0.0058

GLY 1847 GLN 1848 0.0040

GLN 1848 LEU 1849 0.0023

LEU 1849 PHE 1850 0.0016

PHE 1850 VAL 1851 0.0016

VAL 1851 PRO 1852 0.0011

PRO 1852 ARG 1853 0.1568

ARG 1853 ILE 1854 0.0223

ILE 1854 SER 1855 0.0279

SER 1855 CYS 1856 0.0226

CYS 1856 ASP 1857 0.0278

ASP 1857 ILE 1858 0.0226

ILE 1858 ALA 1859 0.0265

ALA 1859 ARG 1860 0.0357

ARG 1860 ASN 1861 0.0032

ASN 1861 GLU 1862 0.0338

GLU 1862 ASP 1863 0.0274

ASP 1863 LEU 1864 0.0282

LEU 1864 SER 1865 0.0076

SER 1865 SER 1866 0.0345

SER 1866 ASP 1867 0.0272

ASP 1867 SER 1868 0.0103

SER 1868 ASN 1869 -0.0482

ASN 1869 SER 1870 0.0391

SER 1870 PRO 1871 0.0376

PRO 1871 ALA 1872 0.0041

ALA 1872 GLN 1873 0.0435

GLN 1873 MET 1874 0.0121

MET 1874 GLU 1875 0.0359

GLU 1875 PRO 1876 0.0062

PRO 1876 PHE 1877 0.0289

PHE 1877 HIS 1878 0.0347

HIS 1878 GLN 1879 0.0258

GLN 1879 PRO 1880 0.0406

PRO 1880 GLY 1881 0.0387

GLY 1881 LYS 1882 0.0355

LYS 1882 LEU 1883 0.0381

LEU 1883 LEU 1884 0.0425

LEU 1884 GLN 1885 0.0664

GLN 1885 MET 1886 0.0356

MET 1886 GLY 1887 0.0150

GLY 1887 ILE 1888 0.0311

ILE 1888 LYS 1889 0.0082

LYS 1889 THR 1890 0.0344

THR 1890 PRO 1891 0.0276

PRO 1891 GLY 1892 0.0318

GLY 1892 LEU 1893 0.0341

LEU 1893 ILE 1894 0.0053

ILE 1894 ASP 1895 0.0346

ASP 1895 THR 1896 0.0213

THR 1896 LEU 1897 0.0168

LEU 1897 GLN 1898 0.0340

GLN 1898 PHE 1899 0.0347

PHE 1899 SER 1900 0.0171

SER 1900 LYS 1901 0.0770

LYS 1901 THR 1902 0.0400

THR 1902 ASP 1903 0.0390

ASP 1903 ALA 1904 0.0121

ALA 1904 THR 1905 0.0397

THR 1905 ASP 1906 0.0281

ASP 1906 ASN 1907 0.0375

ASN 1907 LEU 1908 0.0119

LEU 1908 PRO 1909 0.0400

PRO 1909 ASN 1910 0.0191

ASN 1910 ASP 1911 0.0281

ASP 1911 TYR 1912 0.0396

TYR 1912 ILE 1913 0.0287

ILE 1913 GLU 1914 0.0355

GLU 1914 ILE 1915 0.0278

ILE 1915 GLU 1916 0.0398

GLU 1916 PRO 1917 0.0187

PRO 1917 LYS 1918 0.0226

LYS 1918 ALA 1919 0.0423

ALA 1919 PHE 1920 0.0298

PHE 1920 GLY 1921 0.0406

GLY 1921 LEU 1922 0.0256

LEU 1922 ASN 1923 0.0399

ASN 1923 PHE 1924 0.0363

PHE 1924 ARG 1925 0.0208

ARG 1925 ASP 1926 0.0388

ASP 1926 VAL 1927 0.0412

VAL 1927 MET 1928 0.0323

MET 1928 VAL 1929 0.0277

VAL 1929 ALA 1930 0.0418

ALA 1930 MET 1931 0.0400

MET 1931 GLY 1932 0.0253

GLY 1932 GLN 1933 0.0608

GLN 1933 LEU 1934 0.0417

LEU 1934 GLU 1935 0.0190

GLU 1935 GLU 1936 0.0356

GLU 1936 SER 1937 0.0415

SER 1937 ILE 1938 0.0153

ILE 1938 MET 1939 0.0186

MET 1939 GLY 1940 0.0119

GLY 1940 PHE 1941 0.0289

PHE 1941 GLU 1942 0.0121

GLU 1942 CYS 1943 0.0367

CYS 1943 ALA 1944 0.0163

ALA 1944 GLY 1945 0.0413

GLY 1945 VAL 1946 0.0419

VAL 1946 VAL 1947 0.0345

VAL 1947 ARG 1948 0.0239

ARG 1948 ARG 1949 0.0159

ARG 1949 VAL 1950 0.0391

VAL 1950 GLY 1951 0.0245

GLY 1951 PRO 1952 0.0385

PRO 1952 SER 1953 0.0369

SER 1953 SER 1954 0.0309

SER 1954 ALA 1955 0.0272

ALA 1955 GLY 1956 0.0325

GLY 1956 HIS 1957 0.0356

HIS 1957 ASN 1958 0.0235

ASN 1958 ILE 1959 0.0250

ILE 1959 LYS 1960 0.0405

LYS 1960 VAL 1961 0.0308

VAL 1961 GLY 1962 0.0281

GLY 1962 ASP 1963 0.0331

ASP 1963 ARG 1964 0.0398

ARG 1964 VAL 1965 0.0670

VAL 1965 CYS 1966 0.0367

CYS 1966 ALA 1967 0.0138

ALA 1967 LEU 1968 0.0292

LEU 1968 LEU 1969 0.0039

LEU 1969 GLY 1970 0.0091

GLY 1970 GLY 1971 0.0385

GLY 1971 GLN 1972 0.0390

GLN 1972 TRP 1973 0.0360

TRP 1973 THR 1974 0.0399

THR 1974 ASN 1975 0.0334

ASN 1975 THR 1976 0.0406

THR 1976 VAL 1977 0.0395

VAL 1977 ARG 1978 0.0388

ARG 1978 VAL 1979 0.0322

VAL 1979 HIS 1980 0.0388

HIS 1980 TRP 1981 -0.0047

TRP 1981 HIS 1982 0.0375

HIS 1982 SER 1983 0.0410

SER 1983 VAL 1984 0.0254

VAL 1984 ALA 1985 0.0002

ALA 1985 PRO 1986 0.0251

PRO 1986 ILE 1987 0.0306

ILE 1987 PRO 1988 0.0029

PRO 1988 GLN 1989 0.0408

GLN 1989 ALA 1990 0.0300

ALA 1990 MET 1991 0.0204

MET 1991 ASP 1992 0.0271

ASP 1992 TRP 1993 0.0005

TRP 1993 GLU 1994 0.0413

GLU 1994 THR 1995 0.0248

THR 1995 ALA 1996 0.0326

ALA 1996 ALA 1997 0.0030

ALA 1997 SER 1998 0.0338

SER 1998 ILE 1999 0.0368

ILE 1999 PRO 2000 0.0157

PRO 2000 ILE 2001 0.0259

ILE 2001 VAL 2002 0.0196

VAL 2002 PHE 2003 0.0234

PHE 2003 VAL 2004 0.0194

VAL 2004 THR 2005 0.0316

THR 2005 ALA 2006 0.0081

ALA 2006 TYR 2007 0.0355

TYR 2007 ILE 2008 0.0106

ILE 2008 SER 2009 0.0384

SER 2009 LEU 2010 0.0035

LEU 2010 VAL 2011 0.0344

VAL 2011 LYS 2012 0.0140

LYS 2012 ILE 2013 0.1799

ILE 2013 ALA 2014 0.0189

ALA 2014 ARG 2015 0.0124

ARG 2015 MET 2016 0.0153

MET 2016 GLN 2017 0.0067

GLN 2017 ALA 2018 0.0039

ALA 2018 GLY 2019 0.0263

GLY 2019 GLU 2020 0.0013

GLU 2020 THR 2021 0.0238

THR 2021 VAL 2022 0.0163

VAL 2022 LEU 2023 0.0188

LEU 2023 ILE 2024 0.0255

ILE 2024 HIS 2025 0.0145

HIS 2025 ALA 2026 0.0261

ALA 2026 ALA 2027 0.0031

ALA 2027 SER 2028 0.0246

SER 2028 GLY 2029 0.0028

GLY 2029 GLY 2030 0.0352

GLY 2030 VAL 2031 0.0329

VAL 2031 GLY 2032 0.0279

GLY 2032 GLN 2033 0.0101

GLN 2033 ALA 2034 0.0355

ALA 2034 ALA 2035 0.0350

ALA 2035 ILE 2036 0.0115

ILE 2036 ILE 2037 0.0266

ILE 2037 LEU 2038 0.0320

LEU 2038 ALA 2039 0.0356

ALA 2039 LYS 2040 0.0033

LYS 2040 HIS 2041 0.0353

HIS 2041 VAL 2042 0.0315

VAL 2042 GLY 2043 0.0233

GLY 2043 ALA 2044 0.0175

ALA 2044 GLU 2045 0.0392

GLU 2045 ILE 2046 0.0219

ILE 2046 PHE 2047 0.0214

PHE 2047 ALA 2048 0.0254

ALA 2048 THR 2049 0.0167

THR 2049 VAL 2050 0.0318

VAL 2050 GLY 2051 0.0213

GLY 2051 THR 2052 0.0169

THR 2052 ASP 2053 0.0025

ASP 2053 GLU 2054 0.0298

GLU 2054 LYS 2055 0.0280

LYS 2055 ARG 2056 0.0232

ARG 2056 ASP 2057 0.0098

ASP 2057 LEU 2058 0.0314

LEU 2058 LEU 2059 0.0319

LEU 2059 ILE 2060 0.0096

ILE 2060 LYS 2061 0.0415

LYS 2061 GLU 2062 0.0317

GLU 2062 TYR 2063 0.0318

TYR 2063 LYS 2064 0.0223

LYS 2064 ILE 2065 0.0143

ILE 2065 PRO 2066 0.0318

PRO 2066 ASP 2067 0.0270

ASP 2067 ASP 2068 0.0305

ASP 2068 HIS 2069 0.0269

HIS 2069 ILE 2070 0.0245

ILE 2070 PHE 2071 0.0084

PHE 2071 SER 2072 0.0141

SER 2072 SER 2073 0.0163

SER 2073 ARG 2074 0.0210

ARG 2074 ASN 2075 0.0341

ASN 2075 ALA 2076 0.0340

ALA 2076 LEU 2077 0.0092

LEU 2077 PHE 2078 0.0144

PHE 2078 ALA 2079 0.0179

ALA 2079 LYS 2080 0.0203

LYS 2080 SER 2081 0.0034

SER 2081 ILE 2082 0.0212

ILE 2082 ARG 2083 0.0200

ARG 2083 GLN 2084 0.0134

GLN 2084 ARG 2085 0.0098

ARG 2085 THR 2086 0.0207

THR 2086 ASN 2087 0.0217

ASN 2087 GLY 2088 0.0004

GLY 2088 LYS 2089 0.0217

LYS 2089 GLY 2090 0.0191

GLY 2090 VAL 2091 0.0205

VAL 2091 ASP 2092 0.0218

ASP 2092 VAL 2093 -0.0162

VAL 2093 VAL 2094 0.0096

VAL 2094 LEU 2095 0.0178

LEU 2095 ASN 2096 0.0034

ASN 2096 CYS 2097 0.0133

CYS 2097 LEU 2098 0.0124

LEU 2098 ALA 2099 0.0009

ALA 2099 GLY 2100 0.0099

GLY 2100 GLY 2101 0.0168

GLY 2101 LEU 2102 0.0018

LEU 2102 LEU 2103 0.0177

LEU 2103 GLN 2104 0.0163

GLN 2104 GLU 2105 0.0105

GLU 2105 SER 2106 0.0087

SER 2106 PHE 2107 0.0166

PHE 2107 ASP 2108 0.0180

ASP 2108 CYS 2109 0.0084

CYS 2109 LEU 2110 0.0146

LEU 2110 ALA 2111 0.0111

ALA 2111 ASP 2112 0.0165

ASP 2112 PHE 2113 0.0160

PHE 2113 GLY 2114 0.0168

GLY 2114 ARG 2115 0.0164

ARG 2115 PHE 2116 0.0088

PHE 2116 ILE 2117 0.0165

ILE 2117 GLU 2118 0.0065

GLU 2118 ILE 2119 0.0163

ILE 2119 GLY 2120 0.0050

GLY 2120 LYS 2121 0.0074

LYS 2121 ARG 2122 0.0074

ARG 2122 ASP 2123 0.0154

ASP 2123 ILE 2124 0.0165

ILE 2124 GLU 2125 0.0054

GLU 2125 LEU 2126 0.0037

LEU 2126 ASN 2127 0.0097

ASN 2127 HIS 2128 0.0097

HIS 2128 CYS 2129 0.0098

CYS 2129 LEU 2130 0.0035

LEU 2130 ASN 2131 0.0099

ASN 2131 MET 2132 0.0091

MET 2132 GLY 2133 0.0096

GLY 2133 MET 2134 0.0010

MET 2134 PHE 2135 0.0093

PHE 2135 ALA 2136 0.0096

ALA 2136 ARG 2137 0.0026

ARG 2137 SER 2138 0.0080

SER 2138 ALA 2139 0.0099

ALA 2139 THR 2140 0.0094

THR 2140 PHE 2141 -0.0425

PHE 2141 THR 2142 0.0301

THR 2142 ALA 2143 0.0225

ALA 2143 VAL 2144 0.0319

VAL 2144 ASP 2145 0.0177

ASP 2145 LEU 2146 0.0313

LEU 2146 ILE 2147 0.0039

ILE 2147 ALA 2148 0.0302

ALA 2148 ILE 2149 0.0120

ILE 2149 GLY 2150 0.0322

GLY 2150 ARG 2151 0.0037

ARG 2151 ASP 2152 0.0329

ASP 2152 ARG 2153 0.0022

ARG 2153 SER 2154 0.0310

SER 2154 TYR 2155 0.0181

TYR 2155 MET 2156 0.0231

MET 2156 PHE 2157 0.1242

PHE 2157 ALA 2158 0.0380

ALA 2158 GLU 2159 0.0216

GLU 2159 ALA 2160 0.0397

ALA 2160 LEU 2161 0.0421

LEU 2161 PRO 2162 0.0277

PRO 2162 LYS 2163 0.0258

LYS 2163 ILE 2164 0.0423

ILE 2164 MET 2165 0.0403

MET 2165 THR 2166 0.0200

THR 2166 LEU 2167 0.0357

LEU 2167 LEU 2168 0.0419

LEU 2168 GLN 2169 0.0357

GLN 2169 GLU 2170 0.0200

GLU 2170 LYS 2171 0.0417

LYS 2171 ALA 2172 0.0416

ALA 2172 ILE 2173 0.0434

ILE 2173 ARG 2174 0.0394

ARG 2174 PRO 2175 0.0133

PRO 2175 VAL 2176 0.0313

VAL 2176 THR 2177 0.0376

THR 2177 PRO 2178 0.0363

PRO 2178 ILE 2179 0.0259

ILE 2179 SER 2180 0.0271

SER 2180 ILE 2181 0.0373

ILE 2181 TYR 2182 0.0117

TYR 2182 LYS 2183 0.0335

LYS 2183 ILE 2184 0.0081

ILE 2184 GLY 2185 0.0350

GLY 2185 ASP 2186 0.0371

ASP 2186 ILE 2187 0.0344

ILE 2187 GLU 2188 0.0282

GLU 2188 THR 2189 0.0271

THR 2189 ALA 2190 0.0370

ALA 2190 PHE 2191 0.0141

PHE 2191 ARG 2192 0.0435

ARG 2192 LEU 2193 0.0026

LEU 2193 MET 2194 0.0425

MET 2194 GLN 2195 0.0143

GLN 2195 ALA 2196 0.0319

ALA 2196 GLY 2197 0.0263

GLY 2197 LYS 2198 0.0186

LYS 2198 HIS 2199 0.0357

HIS 2199 MET 2200 0.0145

MET 2200 GLY 2201 0.0419

GLY 2201 LYS 2202 0.0283

LYS 2202 ILE 2203 0.0300

ILE 2203 VAL 2204 0.0435

VAL 2204 ILE 2205 0.1602

ILE 2205 THR 2206 0.0412

THR 2206 ALA 2207 0.0276

ALA 2207 PRO 2208 0.0387

PRO 2208 GLU 2209 0.0359

GLU 2209 ASP 2210 0.0373

ASP 2210 ALA 2211 0.0387

ALA 2211 MET 2212 0.0038

MET 2212 VAL 2213 0.0313

VAL 2213 PRO 2214 0.0045

PRO 2214 VAL 2215 0.0346

VAL 2215 ILE 2216 0.0049

ILE 2216 THR 2217 0.0367

THR 2217 ARG 2218 0.0307

ARG 2218 PRO 2219 0.0179

PRO 2219 PRO 2220 0.0445

PRO 2220 LYS 2221 0.2280

LYS 2221 LEU 2222 0.0179

LEU 2222 GLN 2223 0.0452

GLN 2223 LEU 2224 0.0219

LEU 2224 ARG 2225 0.0380

ARG 2225 PRO 2226 0.0424

PRO 2226 ASP 2227 0.0111

ASP 2227 ALA 2228 0.0338

ALA 2228 SER 2229 0.0444

SER 2229 TYR 2230 0.0455

TYR 2230 LEU 2231 0.0311

LEU 2231 ILE 2232 0.0397

ILE 2232 VAL 2233 0.0294

VAL 2233 GLY 2234 0.0328

GLY 2234 GLY 2235 0.0231

GLY 2235 LEU 2236 0.0404

LEU 2236 GLY 2237 0.0709

GLY 2237 GLY 2238 0.0104

GLY 2238 ILE 2239 0.0431

ILE 2239 GLY 2240 0.0336

GLY 2240 ARG 2241 0.0172

ARG 2241 SER 2242 0.0316

SER 2242 LEU 2243 0.0258

LEU 2243 CYS 2244 0.0455

CYS 2244 LYS 2245 0.0003

LYS 2245 ASN 2246 0.0453

ASN 2246 PHE 2247 0.0210

PHE 2247 VAL 2248 0.0363

VAL 2248 GLU 2249 0.0122

GLU 2249 ASN 2250 0.0340

ASN 2250 GLY 2251 0.0390

GLY 2251 ALA 2252 0.0170

ALA 2252 ARG 2253 0.0421

ARG 2253 SER 2254 0.0109

SER 2254 LEU 2255 0.0451

LEU 2255 VAL 2256 0.0143

VAL 2256 LEU 2257 0.0464

LEU 2257 LEU 2258 0.0147

LEU 2258 SER 2259 0.0466

SER 2259 ARG 2260 0.0273

ARG 2260 ASN 2261 0.0301

ASN 2261 ALA 2262 0.0392

ALA 2262 ASN 2263 0.0461

ASN 2263 VAL 2264 0.0170

VAL 2264 SER 2265 0.0347

SER 2265 GLN 2266 0.0275

GLN 2266 GLN 2267 0.0418

GLN 2267 SER 2268 0.0469

SER 2268 GLY 2269 0.0325

GLY 2269 GLU 2270 0.0063

GLU 2270 PHE 2271 0.0424

PHE 2271 LEU 2272 0.0261

LEU 2272 ASP 2273 0.0266

ASP 2273 GLU 2274 0.0296

GLU 2274 LEU 2275 0.0258

LEU 2275 ARG 2276 0.0451

ARG 2276 SER 2277 0.0032

SER 2277 THR 2278 0.0474

THR 2278 GLY 2279 0.0252

GLY 2279 CYS 2280 0.0229

CYS 2280 ILE 2281 0.0090

ILE 2281 VAL 2282 0.0443

VAL 2282 GLY 2283 0.0045

GLY 2283 VAL 2284 0.0466

VAL 2284 VAL 2285 -0.0391

VAL 2285 ASP 2286 0.0408

ASP 2286 CYS 2287 0.0314

CYS 2287 ASP 2288 0.0443

ASP 2288 ILE 2289 0.0484

ILE 2289 SER 2290 0.0305

SER 2290 SER 2291 0.0309

SER 2291 LYS 2292 0.0384

LYS 2292 THR 2293 0.0471

THR 2293 GLN 2294 0.0045

GLN 2294 VAL 2295 0.0454

VAL 2295 GLU 2296 0.0261

GLU 2296 ALA 2297 0.0470

ALA 2297 THR 2298 0.0027

THR 2298 MET 2299 0.0488

MET 2299 LEU 2300 0.0364

LEU 2300 ARG 2301 0.0087

ARG 2301 LEU 2302 0.0233

LEU 2302 LYS 2303 0.0395

LYS 2303 LYS 2304 0.0469

LYS 2304 ASP 2305 0.0114

ASP 2305 MET 2306 0.0345

MET 2306 LEU 2307 0.0455

LEU 2307 PRO 2308 0.0296

PRO 2308 ILE 2309 0.0474

ILE 2309 ARG 2310 0.0413

ARG 2310 GLY 2311 0.0451

GLY 2311 ILE 2312 0.0452

ILE 2312 VAL 2313 0.0380

VAL 2313 HIS 2314 0.0327

HIS 2314 ALA 2315 0.0299

ALA 2315 GLY 2316 0.0276

GLY 2316 MET 2317 0.2128

MET 2317 VAL 2318 0.0207

VAL 2318 LEU 2319 0.0215

LEU 2319 GLN 2320 0.0154

GLN 2320 ASP 2321 0.0211

ASP 2321 SER 2322 0.0134

SER 2322 VAL 2323 0.0201

VAL 2323 PHE 2324 0.0047

PHE 2324 GLU 2325 0.0171

GLU 2325 ARG 2326 0.0194

ARG 2326 MET 2327 0.0222

MET 2327 SER 2328 0.0138

SER 2328 LEU 2329 0.0150

LEU 2329 ASP 2330 0.0157

ASP 2330 ASP 2331 0.0063

ASP 2331 TYR 2332 0.0188

TYR 2332 ASN 2333 0.1045

ASN 2333 THR 2334 0.0081

THR 2334 ALA 2335 0.0240

ALA 2335 ILE 2336 0.0196

ILE 2336 ARG 2337 0.0313

ARG 2337 PRO 2338 0.0104

PRO 2338 LYS 2339 0.0325

LYS 2339 VAL 2340 0.0008

VAL 2340 GLN 2341 0.0267

GLN 2341 GLY 2342 0.0094

GLY 2342 SER 2343 0.0316

SER 2343 TRP 2344 0.0024

TRP 2344 ASN 2345 0.0325

ASN 2345 LEU 2346 0.0106

LEU 2346 HIS 2347 0.0264

HIS 2347 SER 2348 0.0118

SER 2348 GLY 2349 0.0067

GLY 2349 LEU 2350 0.0280

LEU 2350 SER 2351 0.0240

SER 2351 ASP 2352 0.0440

ASP 2352 CYS 2353 0.0001

CYS 2353 ASP 2354 0.0348

ASP 2354 LEU 2355 0.0220

LEU 2355 ASP 2356 0.0139

ASP 2356 PHE 2357 0.0438

PHE 2357 PHE 2358 0.0353

PHE 2358 ILE 2359 0.0287

ILE 2359 MET 2360 0.0412

MET 2360 LEU 2361 0.0213

LEU 2361 SER 2362 0.0348

SER 2362 SER 2363 0.0343

SER 2363 LEU 2364 0.0389

LEU 2364 ALA 2365 0.0298

ALA 2365 GLY 2366 0.0067

GLY 2366 VAL 2367 0.0219

VAL 2367 SER 2368 0.0191

SER 2368 GLY 2369 0.0171

GLY 2369 SER 2370 0.0164

SER 2370 ALA 2371 0.0209

ALA 2371 SER 2372 0.0213

SER 2372 GLN 2373 0.0226

GLN 2373 ALA 2374 0.0018

ALA 2374 ASN 2375 0.0227

ASN 2375 TYR 2376 0.0072

TYR 2376 THR 2377 0.0215

THR 2377 ALA 2378 0.0038

ALA 2378 GLY 2379 0.0186

GLY 2379 GLY 2380 0.0141

GLY 2380 ALA 2381 -0.0038

ALA 2381 TYR 2382 0.0229

TYR 2382 GLN 2383 0.0192

GLN 2383 ASP 2384 0.0351

ASP 2384 ALA 2385 0.0018

ALA 2385 LEU 2386 0.0358

LEU 2386 ALA 2387 0.0163

ALA 2387 LYS 2388 0.0275

LYS 2388 TYR 2389 0.0108

TYR 2389 ARG 2390 0.0295

ARG 2390 ARG 2391 0.0299

ARG 2391 ALA 2392 0.0085

ALA 2392 GLN 2393 0.0313

GLN 2393 GLY 2394 0.0172

GLY 2394 LEU 2395 0.0283

LEU 2395 SER 2396 0.0024

SER 2396 ALA 2397 0.0119

ALA 2397 VAL 2398 0.0192

VAL 2398 SER 2399 0.0369

SER 2399 ILE 2400 0.0061

ILE 2400 ASP 2401 0.0365

ASP 2401 LEU 2402 0.0108

LEU 2402 GLY 2403 0.0245

GLY 2403 MET 2404 0.0230

MET 2404 VAL 2405 0.0253

VAL 2405 GLN 2406 0.0071

GLN 2406 SER 2407 0.0312

SER 2407 VAL 2408 0.0144

VAL 2408 GLY 2409 0.0089

GLY 2409 TYR 2410 0.0307

TYR 2410 VAL 2411 0.0256

VAL 2411 ALA 2412 0.0106

ALA 2412 GLU 2413 0.0242

GLU 2413 THR 2414 0.0331

THR 2414 LYS 2415 0.0222

LYS 2415 GLY 2416 0.0355

GLY 2416 VAL 2417 0.0180

VAL 2417 ALA 2418 0.0260

ALA 2418 GLU 2419 0.0334

GLU 2419 ARG 2420 0.0051

ARG 2420 LEU 2421 0.0327

LEU 2421 VAL 2422 0.0177

VAL 2422 ARG 2423 0.0354

ARG 2423 MET 2424 0.0030

MET 2424 GLY 2425 0.0348

GLY 2425 TYR 2426 0.0373

TYR 2426 SER 2427 0.0174

SER 2427 PRO 2428 0.0290

PRO 2428 ILE 2429 0.0820

ILE 2429 SER 2430 0.0184

SER 2430 GLU 2431 0.0361

GLU 2431 MET 2432 0.0312

MET 2432 GLU 2433 0.0237

GLU 2433 VAL 2434 0.0146

VAL 2434 LEU 2435 0.0335

LEU 2435 LYS 2436 0.0361

LYS 2436 ILE 2437 0.0063

ILE 2437 VAL 2438 0.0317

VAL 2438 GLU 2439 0.0258

GLU 2439 HIS 2440 0.0340

HIS 2440 ALA 2441 0.0037

ALA 2441 ILE 2442 0.0366

ILE 2442 THR 2443 0.0279

THR 2443 ASN 2444 0.0294

ASN 2444 PRO 2445 0.0847

PRO 2445 PRO 2446 0.0350

PRO 2446 PRO 2447 0.0241

PRO 2447 GLU 2448 0.0235

GLU 2448 ALA 2449 0.0313

ALA 2449 SER 2450 0.0354

SER 2450 SER 2451 0.0055

SER 2451 ALA 2452 0.0392

ALA 2452 GLN 2453 0.0305

GLN 2453 ILE 2454 0.0001

ILE 2454 ILE 2455 0.0345

ILE 2455 THR 2456 0.0058

THR 2456 GLY 2457 0.0225

GLY 2457 ILE 2458 0.0397

ILE 2458 SER 2459 0.0114

SER 2459 THR 2460 0.0396

THR 2460 LYS 2461 -0.0442

LYS 2461 PRO 2462 0.0311

PRO 2462 GLY 2463 0.0314

GLY 2463 ARG 2464 0.0280

ARG 2464 HIS 2465 0.0175

HIS 2465 TRP 2466 0.0220

TRP 2466 THR 2467 0.0312

THR 2467 GLU 2468 0.0314

GLU 2468 SER 2469 0.0217

SER 2469 SER 2470 0.0030

SER 2470 TRP 2471 0.0273

TRP 2471 LEU 2472 0.0236

LEU 2472 GLN 2473 0.0226

GLN 2473 ASP 2474 0.0102

ASP 2474 ALA 2475 0.0273

ALA 2475 ARG 2476 0.0311

ARG 2476 PHE 2477 -0.0355

PHE 2477 ALA 2478 0.0261

ALA 2478 THR 2479 0.0283

THR 2479 LEU 2480 0.0023

LEU 2480 ARG 2481 0.0279

ARG 2481 GLU 2482 0.0269

GLU 2482 ARG 2483 0.0199

ARG 2483 ALA 2484 0.0125

ALA 2484 ARG 2485 0.0274

ARG 2485 ASP 2486 0.0288

ASP 2486 VAL 2487 0.0050

VAL 2487 LYS 2488 0.0268

LYS 2488 GLU 2489 0.0242

GLU 2489 LEU 2490 0.0263

LEU 2490 SER 2491 0.0050

SER 2491 ASN 2492 0.0282

ASN 2492 SER 2493 0.0322

SER 2493 GLN 2494 0.0387

GLN 2494 ASN 989 0.0034

ASN 989 LYS 990 0.0031

LYS 990 ALA 991 0.0022

ALA 991 HIS 992 0.0018

HIS 992 ARG 993 0.0017

ARG 993 GLN 994 0.0021

GLN 994 ARG 995 0.0029

ARG 995 VAL 996 0.0035

VAL 996 HIS 997 0.0033

HIS 997 PRO 998 0.0018

PRO 998 PRO 999 0.0030

PRO 999 HIS 1000 0.0024

HIS 1000 ASP 1001 0.0032

ASP 1001 LEU 1002 0.0003

LEU 1002 LEU 1003 0.0030

LEU 1003 GLY 1004 0.0014

GLY 1004 SER 1005 -0.0033

SER 1005 LEU 1006 0.0035

LEU 1006 ILE 1007 0.0047

ILE 1007 VAL 1008 0.0037

VAL 1008 GLY 1009 0.0038

GLY 1009 ARG 1010 0.0003

ARG 1010 ASP 1011 0.0028

ASP 1011 LEU 1012 0.0048

LEU 1012 ARG 1013 0.0002

ARG 1013 GLU 1014 0.0047

GLU 1014 PRO 1015 0.0017

PRO 1015 THR 1016 0.0044

THR 1016 TRP 1017 0.0028

TRP 1017 ARG 1018 0.0035

ARG 1018 HIS 1019 0.0045

HIS 1019 PHE 1020 0.0035

PHE 1020 ILE 1021 -0.0708

ILE 1021 ARG 1022 0.0034

ARG 1022 VAL 1023 0.0043

VAL 1023 GLN 1024 0.0018

GLN 1024 ASP 1025 0.0053

ASP 1025 ILE 1026 0.0049

ILE 1026 PRO 1027 0.0046

PRO 1027 TRP 1028 0.0051

TRP 1028 ILE 1029 0.0003

ILE 1029 ARG 1030 0.0052

ARG 1030 ASP 1031 0.0053

ASP 1031 HIS 1032 0.0006

HIS 1032 VAL 1033 0.0035

VAL 1033 VAL 1034 0.0008

VAL 1034 GLN 1035 0.0042

GLN 1035 SER 1036 0.0028

SER 1036 ALA 1037 0.0722

ALA 1037 LEU 1038 0.0039

LEU 1038 VAL 1039 0.0026

VAL 1039 TYR 1040 0.0052

TYR 1040 PRO 1041 0.0050

PRO 1041 GLY 1042 0.0010

GLY 1042 ALA 1043 0.0040

ALA 1043 GLY 1044 0.0039

GLY 1044 PHE 1045 0.0017

PHE 1045 ILE 1046 0.0052

ILE 1046 CYS 1047 0.0003

CYS 1047 MET 1048 0.0053

MET 1048 ALA 1049 0.0021

ALA 1049 MET 1050 0.0038

MET 1050 GLU 1051 0.0019

GLU 1051 ALA 1052 0.0035

ALA 1052 MET 1053 0.0005

MET 1053 VAL 1054 0.0029

VAL 1054 GLN 1055 0.0051

GLN 1055 LEU 1056 0.0020

LEU 1056 HIS 1057 0.0070

HIS 1057 GLU 1058 0.0007

GLU 1058 LEU 1059 0.0070

LEU 1059 ARG 1060 0.0016

ARG 1060 ASP 1061 0.0071

ASP 1061 SER 1062 0.0046

SER 1062 GLN 1063 0.0043

GLN 1063 SER 1064 0.0063

SER 1064 ARG 1065 0.0018

ARG 1065 LYS 1066 0.0067

LYS 1066 VAL 1067 0.0065

VAL 1067 ALA 1068 0.0048

ALA 1068 GLY 1069 -0.0093

GLY 1069 TYR 1070 0.0051

TYR 1070 ARG 1071 0.0007

ARG 1071 LEU 1072 0.0053

LEU 1072 ALA 1073 0.0008

ALA 1073 GLU 1074 0.0047

GLU 1074 VAL 1075 0.0017

VAL 1075 ASP 1076 0.0057

ASP 1076 ILE 1077 0.0027

ILE 1077 LEU 1078 0.0052

LEU 1078 ARG 1079 0.0026

ARG 1079 ALA 1080 0.0010

ALA 1080 MET 1081 0.0024

MET 1081 LEU 1082 0.0037

LEU 1082 ILE 1083 0.0004

ILE 1083 PRO 1084 0.0041

PRO 1084 ASP 1085 -0.0697

ASP 1085 THR 1086 0.0034

THR 1086 SER 1087 0.0024

SER 1087 GLU 1088 0.0029

GLU 1088 GLY 1089 0.0026

GLY 1089 LEU 1090 0.0010

LEU 1090 GLU 1091 0.0048

GLU 1091 ALA 1092 0.0027

ALA 1092 HIS 1093 0.0044

HIS 1093 ILE 1094 0.0036

ILE 1094 SER 1095 0.0039

SER 1095 LEU 1096 0.0041

LEU 1096 ARG 1097 0.0022

ARG 1097 PRO 1098 0.0043

PRO 1098 CYS 1099 0.0005

CYS 1099 SER 1100 0.0031

SER 1100 THR 1101 0.0065

THR 1101 LYS 1102 0.0020

LYS 1102 LEU 1103 0.0072

LEU 1103 LEU 1104 0.0055

LEU 1104 LEU 1105 0.0021

LEU 1105 THR 1106 0.0066

THR 1106 ASN 1107 0.0006

ASN 1107 GLU 1108 0.0038

GLU 1108 TRP 1109 0.0073

TRP 1109 TYR 1110 0.0049

TYR 1110 ASP 1111 0.0069

ASP 1111 PHE 1112 0.0026

PHE 1112 CYS 1113 0.0070

CYS 1113 VAL 1114 0.0031

VAL 1114 SER 1115 0.0070

SER 1115 SER 1116 0.0032

SER 1116 VAL 1117 -0.0021

VAL 1117 GLY 1118 0.0063

GLY 1118 ASP 1119 0.0047

ASP 1119 ASP 1120 0.0032

ASP 1120 ASP 1121 0.0062

ASP 1121 LYS 1122 0.0013

LYS 1122 PHE 1123 0.0061

PHE 1123 VAL 1124 0.0050

VAL 1124 ASP 1125 0.0055

ASP 1125 HIS 1126 0.0058

HIS 1126 CYS 1127 0.0057

CYS 1127 ARG 1128 0.0045

ARG 1128 GLY 1129 0.0059

GLY 1129 ARG 1130 0.0062

ARG 1130 ILE 1131 0.0027

ILE 1131 THR 1132 0.0058

THR 1132 ILE 1133 -0.0259

ILE 1133 GLU 1134 0.0065

GLU 1134 PHE 1135 0.0069

PHE 1135 ASP 1136 0.0075

ASP 1136 THR 1137 0.0019

THR 1137 SER 1138 0.0074

SER 1138 GLY 1139 0.0022

GLY 1139 SER 1140 0.0074

SER 1140 ALA 1141 0.0071

ALA 1141 ASP 1142 0.0062

ASP 1142 THR 1143 0.0038

THR 1143 PRO 1144 0.0060

PRO 1144 ARG 1145 0.0063

ARG 1145 THR 1146 0.0071

THR 1146 SER 1147 0.0023

SER 1147 LEU 1148 0.0069

LEU 1148 ARG 1149 -0.0514

ARG 1149 GLU 1150 0.0021

GLU 1150 ARG 1151 0.0077

ARG 1151 SER 1152 0.0007

SER 1152 ARG 1153 0.0076

ARG 1153 SER 1154 0.0077

SER 1154 THR 1155 0.0047

THR 1155 GLY 1156 0.0050

GLY 1156 LEU 1157 0.0005

LEU 1157 MET 1158 0.0072

MET 1158 ARG 1159 0.0041

ARG 1159 SER 1160 0.0049

SER 1160 VAL 1161 0.0076

VAL 1161 ASP 1162 0.0047

ASP 1162 PRO 1163 0.0056

PRO 1163 SER 1164 0.0042

SER 1164 ASN 1165 -0.0085

ASN 1165 LEU 1166 0.0012

LEU 1166 TYR 1167 0.0042

TYR 1167 SER 1168 0.0039

SER 1168 PHE 1169 0.0018

PHE 1169 LEU 1170 0.0025

LEU 1170 ARG 1171 0.0040

ARG 1171 ALA 1172 0.0040

ALA 1172 GLN 1173 0.0007

GLN 1173 GLY 1174 0.0039

GLY 1174 ILE 1175 0.0041

ILE 1175 TYR 1176 0.0015

TYR 1176 HIS 1177 0.0034

HIS 1177 GLY 1178 0.0019

GLY 1178 PRO 1179 0.0012

PRO 1179 ILE 1180 0.0034

ILE 1180 PHE 1181 0.0084

PHE 1181 GLN 1182 0.0035

GLN 1182 ASN 1183 0.0053

ASN 1183 LEU 1184 0.0053

LEU 1184 LYS 1185 0.0023

LYS 1185 THR 1186 0.0047

THR 1186 ILE 1187 0.0020

ILE 1187 SER 1188 0.0049

SER 1188 SER 1189 0.0017

SER 1189 ARG 1190 0.0033

ARG 1190 LYS 1191 0.0016

LYS 1191 ASP 1192 0.0033

ASP 1192 HIS 1193 0.0034

HIS 1193 SER 1194 0.0011

SER 1194 GLU 1195 0.0032

GLU 1195 SER 1196 0.0042

SER 1196 SER 1197 0.0431

SER 1197 PHE 1198 0.0041

PHE 1198 VAL 1199 0.0021

VAL 1199 VAL 1200 0.0048

VAL 1200 ALA 1201 0.0041

ALA 1201 ASN 1202 0.0018

ASN 1202 THR 1203 0.0033

THR 1203 ALA 1204 0.0025

ALA 1204 SER 1205 0.0028

SER 1205 VAL 1206 0.0037

VAL 1206 MET 1207 0.0046

MET 1207 PRO 1208 0.0032

PRO 1208 ASN 1209 0.0019

ASN 1209 GLY 1210 0.0042

GLY 1210 PHE 1211 0.0032

PHE 1211 GLN 1212 0.0006

GLN 1212 SER 1213 -0.0033

SER 1213 PRO 1214 0.0057

PRO 1214 HIS 1215 0.0016

HIS 1215 VAL 1216 0.0040

VAL 1216 ILE 1217 0.0058

ILE 1217 HIS 1218 0.0051

HIS 1218 PRO 1219 0.0037

PRO 1219 THR 1220 0.0036

THR 1220 THR 1221 0.0056

THR 1221 LEU 1222 0.0001

LEU 1222 ASP 1223 0.0057

ASP 1223 SER 1224 0.0041

SER 1224 ILE 1225 0.0032

ILE 1225 PHE 1226 0.0029

PHE 1226 GLN 1227 0.0041

GLN 1227 GLY 1228 0.0059

GLY 1228 ALA 1229 0.0138

ALA 1229 TYR 1230 0.0049

TYR 1230 THR 1231 0.0036

THR 1231 ALA 1232 0.0030

ALA 1232 LEU 1233 0.0060

LEU 1233 PRO 1234 0.0050

PRO 1234 GLY 1235 0.0004

GLY 1235 ALA 1236 0.0059

ALA 1236 GLY 1237 0.0045

GLY 1237 LEU 1238 0.0030

LEU 1238 ASP 1239 0.0039

ASP 1239 GLN 1240 0.0028

GLN 1240 ASN 1241 0.0054

ASN 1241 THR 1242 0.0053

THR 1242 ALA 1243 0.0059

ALA 1243 MET 1244 0.0041

MET 1244 ILE 1245 0.0377

ILE 1245 PRO 1246 0.0062

PRO 1246 ARG 1247 0.0009

ARG 1247 SER 1248 0.0060

SER 1248 ILE 1249 0.0063

ILE 1249 GLN 1250 0.0035

GLN 1250 GLU 1251 0.0041

GLU 1251 LEU 1252 0.0003

LEU 1252 TYR 1253 0.0050

TYR 1253 LEU 1254 0.0006

LEU 1254 SER 1255 0.0051

SER 1255 SER 1256 0.0038

SER 1256 ALA 1257 0.0044

ALA 1257 LEU 1258 0.0065

LEU 1258 THR 1259 0.0008

THR 1259 SER 1260 0.0064

SER 1260 ASP 1261 0.0314

ASP 1261 VAL 1262 0.0043

VAL 1262 GLY 1263 0.0059

GLY 1263 GLN 1264 0.0035

GLN 1264 CYS 1265 0.0057

CYS 1265 LEU 1266 0.0004

LEU 1266 VAL 1267 0.0050

VAL 1267 SER 1268 0.0016

SER 1268 ASP 1269 0.0038

ASP 1269 THR 1270 0.0042

THR 1270 SER 1271 0.0021

SER 1271 LEU 1272 0.0052

LEU 1272 ILE 1273 0.0002

ILE 1273 ARG 1274 0.0059

ARG 1274 TYR 1275 0.0049

TYR 1275 ASP 1276 0.0053

ASP 1276 GLY 1277 0.0768

GLY 1277 GLN 1278 0.0064

GLN 1278 SER 1279 0.0074

SER 1279 PHE 1280 0.0067

PHE 1280 THR 1281 0.0068

THR 1281 VAL 1282 0.0044

VAL 1282 ASN 1283 0.0075

ASN 1283 VAL 1284 0.0019

VAL 1284 ASP 1285 0.0064

ASP 1285 VAL 1286 0.0022

VAL 1286 SER 1287 0.0046

SER 1287 SER 1288 0.0016

SER 1288 LYS 1289 0.0035

LYS 1289 ALA 1290 0.0063

ALA 1290 ASP 1291 0.0020

ASP 1291 SER 1292 0.0073

SER 1292 GLU 1293 -0.0077

GLU 1293 HIS 1294 0.0062

HIS 1294 THR 1295 0.0028

THR 1295 PRO 1296 0.0056

PRO 1296 VAL 1297 0.0057

VAL 1297 LEU 1298 0.0049

LEU 1298 GLU 1299 0.0025

GLU 1299 ILE 1300 0.0051

ILE 1300 LYS 1301 0.0017

LYS 1301 GLY 1302 0.0055

GLY 1302 LEU 1303 0.0028

LEU 1303 ARG 1304 0.0054

ARG 1304 ASN 1305 0.0034

ASN 1305 GLN 1306 0.0054

GLN 1306 SER 1307 0.0050

SER 1307 VAL 1308 0.0061

VAL 1308 GLY 1309 0.3303

GLY 1309 GLN 1310 0.0300

GLN 1310 MET 1311 0.0353

MET 1311 ALA 1312 0.0381

ALA 1312 PRO 1313 0.0135

PRO 1313 GLN 1314 0.0326

GLN 1314 PRO 1315 0.0380

PRO 1315 GLY 1316 0.0067

GLY 1316 ASP 1317 0.0313

ASP 1317 SER 1318 0.0365

SER 1318 SER 1319 0.0046

SER 1319 ASN 1320 0.0268

ASN 1320 ASN 1321 0.0378

ASN 1321 ASP 1322 0.0272

ASP 1322 LEU 1323 0.0130

LEU 1323 CYS 1324 0.0251

CYS 1324 PHE 1325 -0.1759

PHE 1325 LYS 1326 0.0045

LYS 1326 LEU 1327 0.0028

LEU 1327 ASP 1328 0.0035

ASP 1328 TRP 1329 0.0039

TRP 1329 ALA 1330 0.0042

ALA 1330 PRO 1331 0.0040

PRO 1331 ASP 1332 0.0014

ASP 1332 ILE 1333 0.0036

ILE 1333 SER 1334 0.0011

SER 1334 SER 1335 0.0044

SER 1335 VAL 1336 0.0001

VAL 1336 LYS 1337 0.0042

LYS 1337 GLN 1338 0.0022

GLN 1338 GLU 1339 0.0032

GLU 1339 ARG 1340 0.0042

ARG 1340 LEU 1341 0.0869

LEU 1341 LYS 1342 0.1074

LYS 1342 GLU 1343 0.0493

GLU 1343 LYS 1344 0.0841

LYS 1344 PHE 1345 0.0152

PHE 1345 GLY 1346 0.1065

GLY 1346 PHE 1347 0.1026

PHE 1347 PRO 1348 0.0802

PRO 1348 LEU 1349 0.0833

LEU 1349 ASP 1350 0.0994

ASP 1350 PRO 1351 0.1062

PRO 1351 THR 1352 0.0413

THR 1352 GLU 1353 0.0765

GLU 1353 ALA 1354 0.0950

ALA 1354 ASP 1355 0.0993

ASP 1355 ILE 1356 0.0207

ILE 1356 ILE 1357 0.1181

ILE 1357 MET 1358 0.1313

MET 1358 GLY 1359 0.0515

GLY 1359 LEU 1360 0.1055

LEU 1360 ARG 1361 0.1263

ARG 1361 GLN 1362 0.1161

GLN 1362 ALA 1363 0.0466

ALA 1363 CYS 1364 0.1286

CYS 1364 ILE 1365 0.1307

ILE 1365 HIS 1366 0.0761

HIS 1366 PHE 1367 0.0803

PHE 1367 ILE 1368 0.1281

ILE 1368 HIS 1369 0.1306

HIS 1369 ARG 1370 0.0430

ARG 1370 SER 1371 0.1120

SER 1371 LEU 1372 0.1252

LEU 1372 GLN 1373 0.0891

GLN 1373 SER 1374 0.0477

SER 1374 LEU 1375 0.1309

LEU 1375 THR 1376 0.0686

THR 1376 ALA 1377 0.1315

ALA 1377 PRO 1378 0.0722

PRO 1378 ASP 1379 0.0958

ASP 1379 ARG 1380 0.0594

ARG 1380 ASP 1381 0.0963

ASP 1381 GLN 1382 0.1214

GLN 1382 LEU 1383 0.0203

LEU 1383 ASP 1384 0.1249

ASP 1384 TRP 1385 0.0582

TRP 1385 HIS 1386 0.0838

HIS 1386 GLN 1387 0.1155

GLN 1387 LYS 1388 0.1279

LYS 1388 ARG 1389 0.0435

ARG 1389 PHE 1390 0.1345

PHE 1390 TYR 1391 0.1152

TYR 1391 ASP 1392 0.0716

ASP 1392 TRP 1393 0.0762

TRP 1393 MET 1394 0.1138

MET 1394 VAL 1395 0.1346

VAL 1395 LEU 1396 0.0113

LEU 1396 GLN 1397 0.1292

GLN 1397 ILE 1398 0.1152

ILE 1398 GLN 1399 0.1004

GLN 1399 LEU 1400 0.0463

LEU 1400 ALA 1401 0.1283

ALA 1401 GLU 1402 0.1328

GLU 1402 GLU 1403 0.0349

GLU 1403 ASP 1404 0.1091

ASP 1404 ARG 1405 0.1068

ARG 1405 LEU 1406 0.1087

LEU 1406 ALA 1407 0.0881

ALA 1407 PRO 1408 0.1063

PRO 1408 ASN 1409 0.0637

ASN 1409 SER 1410 0.0646

SER 1410 SER 1411 0.1001

SER 1411 ALA 1412 0.1267

ALA 1412 TRP 1413 0.1014

TRP 1413 LEU 1414 0.0607

LEU 1414 GLN 1415 0.1282

GLN 1415 CYS 1416 0.1279

CYS 1416 SER 1417 0.0780

SER 1417 SER 1418 0.0636

SER 1418 SER 1419 0.1154

SER 1419 ASP 1420 0.0219

ASP 1420 GLU 1421 0.1210

GLU 1421 GLN 1422 0.1039

GLN 1422 LYS 1423 0.0484

LYS 1423 LEU 1424 0.1025

LEU 1424 LEU 1425 0.0726

LEU 1425 GLU 1426 0.1350

GLU 1426 ASN 1427 0.0014

ASN 1427 VAL 1428 0.1353

VAL 1428 ARG 1429 0.0669

ARG 1429 ALA 1430 0.1072

ALA 1430 SER 1431 0.0261

SER 1431 SER 1432 0.1324

SER 1432 VAL 1433 0.0848

VAL 1433 ASN 1434 0.1317

ASN 1434 GLY 1435 0.1208

GLY 1435 GLN 1436 0.0542

GLN 1436 MET 1437 0.1262

MET 1437 VAL 1438 0.1241

VAL 1438 VAL 1439 0.0856

VAL 1439 HIS 1440 0.0692

HIS 1440 VAL 1441 0.1269

VAL 1441 GLY 1442 0.1226

GLY 1442 LYS 1443 0.0551

LYS 1443 SER 1444 0.0845

SER 1444 MET 1445 0.1034

MET 1445 LEU 1446 0.0646

LEU 1446 ALA 1447 0.0706

ALA 1447 ILE 1448 0.0944

ILE 1448 LEU 1449 0.1263

LEU 1449 ARG 1450 0.0021

ARG 1450 HIS 1451 0.1251

HIS 1451 GLU 1452 0.1098

GLU 1452 ILE 1453 -0.0062

ILE 1453 ALA 1454 0.0987

ALA 1454 PRO 1455 0.0068

PRO 1455 LEU 1456 0.1211

LEU 1456 GLU 1457 0.0704

GLU 1457 LEU 1458 0.1168

LEU 1458 MET 1459 0.0179

MET 1459 LEU 1460 0.1190

LEU 1460 GLN 1461 0.1060

GLN 1461 ASP 1462 0.1036

ASP 1462 LYS 1463 0.0843

LYS 1463 LEU 1464 0.1029

LEU 1464 LEU 1465 0.1197

LEU 1465 TYR 1466 0.1111

TYR 1466 ARG 1467 0.1010

ARG 1467 TYR 1468 0.1189

TYR 1468 TYR 1469 0.0366

TYR 1469 THR 1470 0.0744

THR 1470 ASP 1471 0.0925

ASP 1471 ALA 1472 0.0943

ALA 1472 ILE 1473 0.0297

ILE 1473 LYS 1474 0.0478

LYS 1474 TRP 1475 0.0815

TRP 1475 ASP 1476 0.0698

ASP 1476 ARG 1477 0.0262

ARG 1477 SER 1478 0.0891

SER 1478 TYR 1479 0.0863

TYR 1479 GLN 1480 0.0264

GLN 1480 GLN 1481 0.0741

GLN 1481 ILE 1482 0.0653

ILE 1482 ASP 1483 0.0922

ASP 1483 GLN 1484 0.0027

GLN 1484 LEU 1485 0.1036

LEU 1485 VAL 1486 0.0300

VAL 1486 LYS 1487 0.0208

LYS 1487 LEU 1488 0.0143

LEU 1488 HIS 1489 0.0301

HIS 1489 ALA 1490 0.0327

ALA 1490 HIS 1491 0.0056

HIS 1491 LYS 1492 0.0288

LYS 1492 CYS 1493 0.0216

CYS 1493 PRO 1494 0.0293

PRO 1494 THR 1495 0.0300

THR 1495 ALA 1496 0.0241

ALA 1496 LYS 1497 0.0111

LYS 1497 ILE 1498 0.0200

ILE 1498 ILE 1499 0.0070

ILE 1499 GLU 1500 0.0194

GLU 1500 ILE 1501 0.0277

ILE 1501 GLY 1502 0.0221

GLY 1502 ALA 1503 0.0489

ALA 1503 GLY 1504 0.0115

GLY 1504 THR 1505 0.0564

THR 1505 GLY 1506 0.0030

GLY 1506 GLY 1507 0.0497

GLY 1507 CYS 1508 0.0222

CYS 1508 THR 1509 0.0562

THR 1509 ARG 1510 0.0525

ARG 1510 ALA 1511 0.0236

ALA 1511 VAL 1512 0.0531

VAL 1512 LEU 1513 0.0562

LEU 1513 ASP 1514 0.0437

ASP 1514 ALA 1515 0.0297

ALA 1515 LEU 1516 0.0565

LEU 1516 SER 1517 -0.0078

SER 1517 ASN 1518 0.0063

ASN 1518 GLN 1519 0.0242

GLN 1519 GLY 1520 0.0140

GLY 1520 ILE 1521 0.0201

ILE 1521 ALA 1522 0.0206

ALA 1522 ARG 1523 0.0162

ARG 1523 CYS 1524 0.0178

CYS 1524 ALA 1525 0.0246

ALA 1525 GLN 1526 0.0005

GLN 1526 TYR 1527 0.0134

TYR 1527 ASP 1528 0.0069

ASP 1528 PHE 1529 0.0116

PHE 1529 THR 1530 0.0123

THR 1530 ASP 1531 0.0049

ASP 1531 VAL 1532 0.0095

VAL 1532 SER 1533 0.0793

SER 1533 SER 1534 0.0590

SER 1534 GLY 1535 0.0457

GLY 1535 PHE 1536 0.0185

PHE 1536 PHE 1537 0.0477

PHE 1537 GLU 1538 0.0491

GLU 1538 ALA 1539 0.0558

ALA 1539 ALA 1540 0.0097

ALA 1540 GLN 1541 0.0584

GLN 1541 GLN 1542 0.0564

GLN 1542 LYS 1543 0.0390

LYS 1543 PHE 1544 0.0238

PHE 1544 ALA 1545 0.0588

ALA 1545 ALA 1546 0.0065

ALA 1546 PHE 1547 0.0547

PHE 1547 ASP 1548 0.0351

ASP 1548 ASP 1549 -0.0103

ASP 1549 VAL 1550 0.0638

VAL 1550 ILE 1551 0.0166

ILE 1551 ARG 1552 0.0378

ARG 1552 PHE 1553 0.0139

PHE 1553 GLN 1554 0.0548

GLN 1554 LYS 1555 0.0393

LYS 1555 LEU 1556 0.0581

LEU 1556 ASP 1557 0.0525

ASP 1557 ILE 1558 0.0303

ILE 1558 GLU 1559 0.0449

GLU 1559 LYS 1560 0.0649

LYS 1560 ASP 1561 0.0395

ASP 1561 ILE 1562 0.0399

ILE 1562 GLU 1563 0.0661

GLU 1563 MET 1564 0.0011

MET 1564 GLN 1565 0.1007

GLN 1565 GLY 1566 0.0506

GLY 1566 PHE 1567 0.0222

PHE 1567 GLU 1568 0.0187

GLU 1568 CYS 1569 0.0555

CYS 1569 GLY 1570 0.0090

GLY 1570 SER 1571 0.0725

SER 1571 TYR 1572 0.0731

TYR 1572 ASP 1573 0.0258

ASP 1573 LEU 1574 0.0561

LEU 1574 VAL 1575 0.0217

VAL 1575 ILE 1576 0.0611

ILE 1576 ALA 1577 0.0391

ALA 1577 SER 1578 0.0658

SER 1578 GLN 1579 0.0426

GLN 1579 VAL 1580 0.0610

VAL 1580 LEU 1581 -0.0183

LEU 1581 HIS 1582 0.0781

HIS 1582 ALA 1583 0.0090

ALA 1583 THR 1584 0.0826

THR 1584 GLY 1585 0.0779

GLY 1585 LYS 1586 0.0207

LYS 1586 MET 1587 0.0245

MET 1587 GLU 1588 0.0583

GLU 1588 HIS 1589 0.0474

HIS 1589 THR 1590 0.0832

THR 1590 MET 1591 0.0007

MET 1591 ALA 1592 0.0828

ALA 1592 ASN 1593 0.0549

ASN 1593 VAL 1594 0.0624

VAL 1594 ARG 1595 0.0278

ARG 1595 LYS 1596 0.0700

LYS 1596 LEU 1597 0.1587

LEU 1597 LEU 1598 0.0040

LEU 1598 LYS 1599 0.0372

LYS 1599 PRO 1600 0.0307

PRO 1600 GLY 1601 0.0614

GLY 1601 GLY 1602 0.0269

GLY 1602 LYS 1603 0.0755

LYS 1603 LEU 1604 0.0351

LEU 1604 LEU 1605 0.0753

LEU 1605 LEU 1606 0.0531

LEU 1606 VAL 1607 0.0668

VAL 1607 GLU 1608 0.0640

GLU 1608 THR 1609 0.0722

THR 1609 THR 1610 0.0387

THR 1610 ARG 1611 0.0722

ARG 1611 ASP 1612 0.0067

ASP 1612 GLU 1613 0.3356

GLU 1613 MET 1614 0.0464

MET 1614 ASP 1615 0.0947

ASP 1615 LEU 1616 0.1167

LEU 1616 GLN 1617 0.1050

GLN 1617 LEU 1618 0.0585

LEU 1618 VAL 1619 0.1067

VAL 1619 PHE 1620 0.1167

PHE 1620 GLY 1621 0.1143

GLY 1621 LEU 1622 0.0067

LEU 1622 LEU 1623 0.1169

LEU 1623 PRO 1624 0.1154

PRO 1624 GLY 1625 0.0551

GLY 1625 TRP 1626 0.0703

TRP 1626 TRP 1627 0.1139

TRP 1627 LEU 1628 0.1168

LEU 1628 SER 1629 -0.0535

SER 1629 SER 1630 0.1092

SER 1630 GLU 1631 0.0045

GLU 1631 GLU 1632 0.1038

GLU 1632 GLU 1633 0.0660

GLU 1633 ARG 1634 0.0586

ARG 1634 GLN 1635 0.0460

GLN 1635 MET 1636 0.1066

MET 1636 SER 1637 0.1020

SER 1637 PRO 1638 0.1079

PRO 1638 SER 1639 0.0163

SER 1639 LEU 1640 0.0279

LEU 1640 SER 1641 0.0229

SER 1641 THR 1642 0.0602

THR 1642 ASN 1643 0.0876

ASN 1643 SER 1644 0.0350

SER 1644 TRP 1645 0.1642

TRP 1645 GLU 1646 0.0101

GLU 1646 LYS 1647 0.0637

LYS 1647 VAL 1648 0.0264

VAL 1648 LEU 1649 0.0517

LEU 1649 LYS 1650 0.0407

LYS 1650 LYS 1651 0.0345

LYS 1651 THR 1652 0.0559

THR 1652 GLY 1653 0.0319

GLY 1653 PHE 1654 0.0562

PHE 1654 ASP 1655 0.0079

ASP 1655 GLY 1656 0.0652

GLY 1656 LEU 1657 0.0709

LEU 1657 ASP 1658 0.0393

ASP 1658 ILE 1659 0.0673

ILE 1659 GLU 1660 0.0532

GLU 1660 LEU 1661 0.1123

LEU 1661 ARG 1662 0.0769

ARG 1662 ASP 1663 0.0653

ASP 1663 CYS 1664 0.0563

CYS 1664 ASP 1665 0.0233

ASP 1665 SER 1666 0.0814

SER 1666 ASP 1667 0.0922

ASP 1667 GLU 1668 0.0502

GLU 1668 PHE 1669 0.0699

PHE 1669 TYR 1670 0.0933

TYR 1670 SER 1671 0.0289

SER 1671 PHE 1672 0.0934

PHE 1672 SER 1673 0.0527

SER 1673 VAL 1674 0.0930

VAL 1674 MET 1675 0.0859

MET 1675 MET 1676 0.0844

MET 1676 ALA 1677 0.3265

ALA 1677 THR 1678 0.0018

THR 1678 ALA 1679 0.0034

ALA 1679 SER 1680 0.0041

SER 1680 SER 1681 0.0044

SER 1681 THR 1682 0.0012

THR 1682 ILE 1683 0.0085

ILE 1683 ALA 1684 0.0005

ALA 1684 SER 1685 0.0072

SER 1685 SER 1686 0.0078

SER 1686 SER 1687 0.0039

SER 1687 MET 1688 0.0068

MET 1688 ALA 1689 0.0087

ALA 1689 PHE 1690 0.0027

PHE 1690 ALA 1691 0.0077

ALA 1691 ILE 1692 0.0029

ILE 1692 VAL 1693 -0.0474

VAL 1693 TYR 1694 0.0035

TYR 1694 GLY 1695 0.0047

GLY 1695 GLU 1696 0.0037

GLU 1696 VAL 1697 0.0010

VAL 1697 PRO 1698 0.0042

PRO 1698 LEU 1699 0.0045

LEU 1699 PRO 1700 0.0003

PRO 1700 ASP 1701 0.0048

ASP 1701 GLN 1702 0.0039

GLN 1702 PHE 1703 0.0019

PHE 1703 LEU 1704 0.0030

LEU 1704 ASP 1705 0.0038

ASP 1705 ASP 1706 0.0048

ASP 1706 MET 1707 0.0000

MET 1707 LYS 1708 0.0048

LYS 1708 THR 1709 0.0294

THR 1709 ALA 1710 0.0040

ALA 1710 ILE 1711 0.0002

ILE 1711 SER 1712 0.0043

SER 1712 SER 1713 0.0036

SER 1713 SER 1714 0.0018

SER 1714 ALA 1715 0.0021

ALA 1715 VAL 1716 0.0037

VAL 1716 SER 1717 0.0041

SER 1717 ASP 1718 0.0017

ASP 1718 PRO 1719 0.0043

PRO 1719 VAL 1720 0.0041

VAL 1720 VAL 1721 0.0026

VAL 1721 GLY 1722 0.0040

GLY 1722 HIS 1723 0.0041

HIS 1723 LEU 1724 0.0018

LEU 1724 ASP 1725 0.0367

ASP 1725 SER 1726 0.0046

SER 1726 ILE 1727 0.0052

ILE 1727 ASP 1728 0.0033

ASP 1728 ALA 1729 0.0042

ALA 1729 THR 1730 0.0033

THR 1730 GLY 1731 0.0054

GLY 1731 LYS 1732 0.0023

LYS 1732 PHE 1733 0.0055

PHE 1733 CYS 1734 0.0046

CYS 1734 ILE 1735 0.0040

ILE 1735 PHE 1736 0.0055

PHE 1736 ILE 1737 0.0030

ILE 1737 GLU 1738 0.0055

GLU 1738 ASP 1739 0.0026

ASP 1739 PRO 1740 0.0052

PRO 1740 GLU 1741 -0.0343

GLU 1741 THR 1742 0.0085

THR 1742 ASP 1743 0.0002

ASP 1743 ILE 1744 0.0103

ILE 1744 LEU 1745 -0.0000

LEU 1745 SER 1746 0.0103

SER 1746 SER 1747 0.0085

SER 1747 PRO 1748 0.0099

PRO 1748 ASP 1749 0.0077

ASP 1749 GLU 1750 0.0098

GLU 1750 LYS 1751 0.0055

LYS 1751 SER 1752 0.0102

SER 1752 TYR 1753 0.0001

TYR 1753 ALA 1754 0.0105

ALA 1754 SER 1755 0.0065

SER 1755 ILE 1756 0.0057

ILE 1756 GLN 1757 0.0101

GLN 1757 LYS 1758 0.0065

LYS 1758 LEU 1759 0.0072

LEU 1759 VAL 1760 0.0028

VAL 1760 THR 1761 0.0066

THR 1761 ARG 1762 0.0046

ARG 1762 CYS 1763 0.0074

CYS 1763 LYS 1764 0.0081

LYS 1764 GLY 1765 0.0089

GLY 1765 LEU 1766 0.0070

LEU 1766 ILE 1767 0.0071

ILE 1767 TRP 1768 0.0087

TRP 1768 VAL 1769 0.0043

VAL 1769 SER 1770 0.0089

SER 1770 ARG 1771 0.0076

ARG 1771 GLY 1772 0.0068

GLY 1772 GLY 1773 -0.0066

GLY 1773 ALA 1774 0.0107

ALA 1774 MET 1775 0.0153

MET 1775 HIS 1776 0.0149

HIS 1776 GLY 1777 0.0158

GLY 1777 THR 1778 0.0038

THR 1778 ARG 1779 0.0156

ARG 1779 PRO 1780 0.0029

PRO 1780 ASN 1781 0.0140

ASN 1781 SER 1782 0.0144

SER 1782 SER 1783 0.0009

SER 1783 LEU 1784 0.0153

LEU 1784 LYS 1785 0.0142

LYS 1785 THR 1786 0.0105

THR 1786 GLY 1787 0.0060

GLY 1787 LEU 1788 0.0144

LEU 1788 LEU 1789 0.0217

LEU 1789 ARG 1790 0.0035

ARG 1790 THR 1791 0.0101

THR 1791 LEU 1792 0.0077

LEU 1792 ARG 1793 0.0122

ARG 1793 LEU 1794 0.0012

LEU 1794 GLU 1795 0.0120

GLU 1795 TYR 1796 0.0076

TYR 1796 THR 1797 0.0116

THR 1797 GLU 1798 0.0075

GLU 1798 LYS 1799 0.0047

LYS 1799 ARG 1800 0.0104

ARG 1800 PHE 1801 0.0125

PHE 1801 ILE 1802 0.0098

ILE 1802 SER 1803 0.0123

SER 1803 LEU 1804 0.0047

LEU 1804 ASP 1805 0.0395

ASP 1805 LEU 1806 0.0004

LEU 1806 ASP 1807 0.0057

ASP 1807 SER 1808 0.0063

SER 1808 ALA 1809 0.0032

ALA 1809 ARG 1810 0.0033

ARG 1810 PRO 1811 0.0048

PRO 1811 GLN 1812 0.0048

GLN 1812 TRP 1813 0.0045

TRP 1813 ASN 1814 0.0051

ASN 1814 HIS 1815 0.0061

HIS 1815 ASP 1816 0.0035

ASP 1816 SER 1817 0.0030

SER 1817 ILE 1818 0.0059

ILE 1818 THR 1819 0.0065

THR 1819 THR 1820 0.0009

THR 1820 ILE 1821 0.0210

ILE 1821 ASN 1822 0.0017

ASN 1822 GLU 1823 0.0026

GLU 1823 VAL 1824 0.0015

VAL 1824 LEU 1825 0.0035

LEU 1825 CYS 1826 0.0003

CYS 1826 GLY 1827 0.0035

GLY 1827 ALA 1828 0.0010

ALA 1828 LEU 1829 0.0027

LEU 1829 ALA 1830 0.0005

ALA 1830 GLN 1831 0.0034

GLN 1831 ASN 1832 0.0031

ASN 1832 ALA 1833 0.0030

ALA 1833 ASP 1834 0.0028

ASP 1834 SER 1835 0.0033

SER 1835 SER 1836 0.0019

SER 1836 ILE 1837 -0.0120

ILE 1837 LYS 1838 0.0049

LYS 1838 ASP 1839 0.0058

ASP 1839 SER 1840 0.0059

SER 1840 GLU 1841 0.0059

GLU 1841 PHE 1842 0.0007

PHE 1842 ALA 1843 0.0052

ALA 1843 GLU 1844 0.0004

GLU 1844 GLN 1845 0.0060

GLN 1845 ASP 1846 0.0006

ASP 1846 GLY 1847 0.0058

GLY 1847 GLN 1848 0.0040

GLN 1848 LEU 1849 0.0022

LEU 1849 PHE 1850 0.0017

PHE 1850 VAL 1851 0.0015

VAL 1851 PRO 1852 0.0008

PRO 1852 ARG 1853 0.1584

ARG 1853 ILE 1854 0.0226

ILE 1854 SER 1855 0.0276

SER 1855 CYS 1856 0.0228

CYS 1856 ASP 1857 0.0271

ASP 1857 ILE 1858 0.0223

ILE 1858 ALA 1859 0.0260

ALA 1859 ARG 1860 0.0353

ARG 1860 ASN 1861 0.0031

ASN 1861 GLU 1862 0.0334

GLU 1862 ASP 1863 0.0268

ASP 1863 LEU 1864 0.0282

LEU 1864 SER 1865 0.0076

SER 1865 SER 1866 0.0338

SER 1866 ASP 1867 0.0271

ASP 1867 SER 1868 0.0100

SER 1868 ASN 1869 -0.0430

ASN 1869 SER 1870 0.0379

SER 1870 PRO 1871 0.0366

PRO 1871 ALA 1872 0.0038

ALA 1872 GLN 1873 0.0418

GLN 1873 MET 1874 0.0118

MET 1874 GLU 1875 0.0344

GLU 1875 PRO 1876 0.0056

PRO 1876 PHE 1877 0.0285

PHE 1877 HIS 1878 0.0337

HIS 1878 GLN 1879 0.0254

GLN 1879 PRO 1880 0.0393

PRO 1880 GLY 1881 0.0378

GLY 1881 LYS 1882 0.0340

LYS 1882 LEU 1883 0.0371

LEU 1883 LEU 1884 0.0411

LEU 1884 GLN 1885 0.0652

GLN 1885 MET 1886 0.0348

MET 1886 GLY 1887 0.0141

GLY 1887 ILE 1888 0.0302

ILE 1888 LYS 1889 0.0082

LYS 1889 THR 1890 0.0334

THR 1890 PRO 1891 0.0277

PRO 1891 GLY 1892 0.0310

GLY 1892 LEU 1893 0.0332

LEU 1893 ILE 1894 0.0049

ILE 1894 ASP 1895 0.0341

ASP 1895 THR 1896 0.0210

THR 1896 LEU 1897 0.0164

LEU 1897 GLN 1898 0.0336

GLN 1898 PHE 1899 0.0339

PHE 1899 SER 1900 0.0167

SER 1900 LYS 1901 0.0755

LYS 1901 THR 1902 0.0388

THR 1902 ASP 1903 0.0379

ASP 1903 ALA 1904 0.0116

ALA 1904 THR 1905 0.0385

THR 1905 ASP 1906 0.0272

ASP 1906 ASN 1907 0.0366

ASN 1907 LEU 1908 0.0120

LEU 1908 PRO 1909 0.0391

PRO 1909 ASN 1910 0.0187

ASN 1910 ASP 1911 0.0276

ASP 1911 TYR 1912 0.0383

TYR 1912 ILE 1913 0.0276

ILE 1913 GLU 1914 0.0346

GLU 1914 ILE 1915 0.0269

ILE 1915 GLU 1916 0.0387

GLU 1916 PRO 1917 0.0186

PRO 1917 LYS 1918 0.0219

LYS 1918 ALA 1919 0.0413

ALA 1919 PHE 1920 0.0287

PHE 1920 GLY 1921 0.0398

GLY 1921 LEU 1922 0.0248

LEU 1922 ASN 1923 0.0388

ASN 1923 PHE 1924 0.0349

PHE 1924 ARG 1925 0.0201

ARG 1925 ASP 1926 0.0381

ASP 1926 VAL 1927 0.0403

VAL 1927 MET 1928 0.0307

MET 1928 VAL 1929 0.0273

VAL 1929 ALA 1930 0.0409

ALA 1930 MET 1931 0.0388

MET 1931 GLY 1932 0.0244

GLY 1932 GLN 1933 0.0615

GLN 1933 LEU 1934 0.0409

LEU 1934 GLU 1935 0.0182

GLU 1935 GLU 1936 0.0347

GLU 1936 SER 1937 0.0407

SER 1937 ILE 1938 0.0144

ILE 1938 MET 1939 0.0178

MET 1939 GLY 1940 0.0112

GLY 1940 PHE 1941 0.0284

PHE 1941 GLU 1942 0.0114

GLU 1942 CYS 1943 0.0353

CYS 1943 ALA 1944 0.0153

ALA 1944 GLY 1945 0.0404

GLY 1945 VAL 1946 0.0411

VAL 1946 VAL 1947 0.0335

VAL 1947 ARG 1948 0.0239

ARG 1948 ARG 1949 0.0144

ARG 1949 VAL 1950 0.0383

VAL 1950 GLY 1951 0.0238

GLY 1951 PRO 1952 0.0377

PRO 1952 SER 1953 0.0364

SER 1953 SER 1954 0.0300

SER 1954 ALA 1955 0.0261

ALA 1955 GLY 1956 0.0321

GLY 1956 HIS 1957 0.0349

HIS 1957 ASN 1958 0.0222

ASN 1958 ILE 1959 0.0249

ILE 1959 LYS 1960 0.0395

LYS 1960 VAL 1961 0.0304

VAL 1961 GLY 1962 0.0274

GLY 1962 ASP 1963 0.0326

ASP 1963 ARG 1964 0.0389

ARG 1964 VAL 1965 0.0651

VAL 1965 CYS 1966 0.0357

CYS 1966 ALA 1967 0.0129

ALA 1967 LEU 1968 0.0280

LEU 1968 LEU 1969 0.0040

LEU 1969 GLY 1970 0.0086

GLY 1970 GLY 1971 0.0375

GLY 1971 GLN 1972 0.0381

GLN 1972 TRP 1973 0.0351

TRP 1973 THR 1974 0.0389

THR 1974 ASN 1975 0.0325

ASN 1975 THR 1976 0.0395

THR 1976 VAL 1977 0.0386

VAL 1977 ARG 1978 0.0380

ARG 1978 VAL 1979 0.0316

VAL 1979 HIS 1980 0.0381

HIS 1980 TRP 1981 -0.0042

TRP 1981 HIS 1982 0.0369

HIS 1982 SER 1983 0.0402

SER 1983 VAL 1984 0.0240

VAL 1984 ALA 1985 0.0003

ALA 1985 PRO 1986 0.0240

PRO 1986 ILE 1987 0.0299

ILE 1987 PRO 1988 0.0025

PRO 1988 GLN 1989 0.0396

GLN 1989 ALA 1990 0.0294

ALA 1990 MET 1991 0.0196

MET 1991 ASP 1992 0.0267

ASP 1992 TRP 1993 0.0004

TRP 1993 GLU 1994 0.0403

GLU 1994 THR 1995 0.0246

THR 1995 ALA 1996 0.0321

ALA 1996 ALA 1997 0.0018

ALA 1997 SER 1998 0.0329

SER 1998 ILE 1999 0.0358

ILE 1999 PRO 2000 0.0151

PRO 2000 ILE 2001 0.0249

ILE 2001 VAL 2002 0.0194

VAL 2002 PHE 2003 0.0228

PHE 2003 VAL 2004 0.0186

VAL 2004 THR 2005 0.0306

THR 2005 ALA 2006 0.0081

ALA 2006 TYR 2007 0.0344

TYR 2007 ILE 2008 0.0101

ILE 2008 SER 2009 0.0372

SER 2009 LEU 2010 0.0036

LEU 2010 VAL 2011 0.0335

VAL 2011 LYS 2012 0.0133

LYS 2012 ILE 2013 0.1840

ILE 2013 ALA 2014 0.0183

ALA 2014 ARG 2015 0.0115

ARG 2015 MET 2016 0.0148

MET 2016 GLN 2017 0.0065

GLN 2017 ALA 2018 0.0038

ALA 2018 GLY 2019 0.0252

GLY 2019 GLU 2020 0.0009

GLU 2020 THR 2021 0.0227

THR 2021 VAL 2022 0.0158

VAL 2022 LEU 2023 0.0180

LEU 2023 ILE 2024 0.0245

ILE 2024 HIS 2025 0.0135

HIS 2025 ALA 2026 0.0252

ALA 2026 ALA 2027 0.0028

ALA 2027 SER 2028 0.0232

SER 2028 GLY 2029 0.0032

GLY 2029 GLY 2030 0.0339

GLY 2030 VAL 2031 0.0315

VAL 2031 GLY 2032 0.0272

GLY 2032 GLN 2033 0.0090

GLN 2033 ALA 2034 0.0345

ALA 2034 ALA 2035 0.0336

ALA 2035 ILE 2036 0.0114

ILE 2036 ILE 2037 0.0253

ILE 2037 LEU 2038 0.0308

LEU 2038 ALA 2039 0.0343

ALA 2039 LYS 2040 0.0028

LYS 2040 HIS 2041 0.0342

HIS 2041 VAL 2042 0.0303

VAL 2042 GLY 2043 0.0229

GLY 2043 ALA 2044 0.0165

ALA 2044 GLU 2045 0.0406

GLU 2045 ILE 2046 0.0210

ILE 2046 PHE 2047 0.0204

PHE 2047 ALA 2048 0.0246

ALA 2048 THR 2049 0.0158

THR 2049 VAL 2050 0.0308

VAL 2050 GLY 2051 0.0203

GLY 2051 THR 2052 0.0165

THR 2052 ASP 2053 0.0025

ASP 2053 GLU 2054 0.0287

GLU 2054 LYS 2055 0.0269

LYS 2055 ARG 2056 0.0228

ARG 2056 ASP 2057 0.0093

ASP 2057 LEU 2058 0.0300

LEU 2058 LEU 2059 0.0307

LEU 2059 ILE 2060 0.0095

ILE 2060 LYS 2061 0.0402

LYS 2061 GLU 2062 0.0308

GLU 2062 TYR 2063 0.0304

TYR 2063 LYS 2064 0.0218

LYS 2064 ILE 2065 0.0136

ILE 2065 PRO 2066 0.0309

PRO 2066 ASP 2067 0.0259

ASP 2067 ASP 2068 0.0291

ASP 2068 HIS 2069 0.0263

HIS 2069 ILE 2070 0.0237

ILE 2070 PHE 2071 0.0079

PHE 2071 SER 2072 0.0135

SER 2072 SER 2073 0.0159

SER 2073 ARG 2074 0.0198

ARG 2074 ASN 2075 0.0326

ASN 2075 ALA 2076 0.0326

ALA 2076 LEU 2077 0.0068

LEU 2077 PHE 2078 0.0130

PHE 2078 ALA 2079 0.0164

ALA 2079 LYS 2080 0.0189

LYS 2080 SER 2081 0.0030

SER 2081 ILE 2082 0.0193

ILE 2082 ARG 2083 0.0182

ARG 2083 GLN 2084 0.0128

GLN 2084 ARG 2085 0.0089

ARG 2085 THR 2086 0.0190

THR 2086 ASN 2087 0.0200

ASN 2087 GLY 2088 0.0004

GLY 2088 LYS 2089 0.0199

LYS 2089 GLY 2090 0.0178

GLY 2090 VAL 2091 0.0188

VAL 2091 ASP 2092 0.0201

ASP 2092 VAL 2093 -0.0136

VAL 2093 VAL 2094 0.0091

VAL 2094 LEU 2095 0.0167

LEU 2095 ASN 2096 0.0029

ASN 2096 CYS 2097 0.0128

CYS 2097 LEU 2098 0.0117

LEU 2098 ALA 2099 0.0007

ALA 2099 GLY 2100 0.0092

GLY 2100 GLY 2101 0.0163

GLY 2101 LEU 2102 0.0017

LEU 2102 LEU 2103 0.0169

LEU 2103 GLN 2104 0.0154

GLN 2104 GLU 2105 0.0104

GLU 2105 SER 2106 0.0081

SER 2106 PHE 2107 0.0158

PHE 2107 ASP 2108 0.0172

ASP 2108 CYS 2109 0.0086

CYS 2109 LEU 2110 0.0134

LEU 2110 ALA 2111 0.0104

ALA 2111 ASP 2112 0.0158

ASP 2112 PHE 2113 0.0149

PHE 2113 GLY 2114 0.0160

GLY 2114 ARG 2115 0.0155

ARG 2115 PHE 2116 0.0086

PHE 2116 ILE 2117 0.0155

ILE 2117 GLU 2118 0.0063

GLU 2118 ILE 2119 0.0153

ILE 2119 GLY 2120 0.0047

GLY 2120 LYS 2121 0.0075

LYS 2121 ARG 2122 0.0068

ARG 2122 ASP 2123 0.0145

ASP 2123 ILE 2124 0.0154

ILE 2124 GLU 2125 0.0040

GLU 2125 LEU 2126 0.0032

LEU 2126 ASN 2127 0.0095

ASN 2127 HIS 2128 0.0093

HIS 2128 CYS 2129 0.0093

CYS 2129 LEU 2130 0.0035

LEU 2130 ASN 2131 0.0093

ASN 2131 MET 2132 0.0085

MET 2132 GLY 2133 0.0093

GLY 2133 MET 2134 0.0011

MET 2134 PHE 2135 0.0088

PHE 2135 ALA 2136 0.0091

ALA 2136 ARG 2137 0.0028

ARG 2137 SER 2138 0.0075

SER 2138 ALA 2139 0.0093

ALA 2139 THR 2140 0.0092

THR 2140 PHE 2141 -0.0333

PHE 2141 THR 2142 0.0299

THR 2142 ALA 2143 0.0227

ALA 2143 VAL 2144 0.0315

VAL 2144 ASP 2145 0.0178

ASP 2145 LEU 2146 0.0308

LEU 2146 ILE 2147 0.0038

ILE 2147 ALA 2148 0.0297

ALA 2148 ILE 2149 0.0120

ILE 2149 GLY 2150 0.0321

GLY 2150 ARG 2151 0.0032

ARG 2151 ASP 2152 0.0325

ASP 2152 ARG 2153 0.0022

ARG 2153 SER 2154 0.0302

SER 2154 TYR 2155 0.0182

TYR 2155 MET 2156 0.0229

MET 2156 PHE 2157 0.1147

PHE 2157 ALA 2158 0.0370

ALA 2158 GLU 2159 0.0218

GLU 2159 ALA 2160 0.0388

ALA 2160 LEU 2161 0.0409

LEU 2161 PRO 2162 0.0268

PRO 2162 LYS 2163 0.0257

LYS 2163 ILE 2164 0.0410

ILE 2164 MET 2165 0.0394

MET 2165 THR 2166 0.0198

THR 2166 LEU 2167 0.0351

LEU 2167 LEU 2168 0.0410

LEU 2168 GLN 2169 0.0341

GLN 2169 GLU 2170 0.0198

GLU 2170 LYS 2171 0.0407

LYS 2171 ALA 2172 0.0403

ALA 2172 ILE 2173 0.0439

ILE 2173 ARG 2174 0.0381

ARG 2174 PRO 2175 0.0134

PRO 2175 VAL 2176 0.0304

VAL 2176 THR 2177 0.0365

THR 2177 PRO 2178 0.0354

PRO 2178 ILE 2179 0.0256

ILE 2179 SER 2180 0.0265

SER 2180 ILE 2181 0.0368

ILE 2181 TYR 2182 0.0119

TYR 2182 LYS 2183 0.0328

LYS 2183 ILE 2184 0.0080

ILE 2184 GLY 2185 0.0342

GLY 2185 ASP 2186 0.0362

ASP 2186 ILE 2187 0.0331

ILE 2187 GLU 2188 0.0271

GLU 2188 THR 2189 0.0266

THR 2189 ALA 2190 0.0361

ALA 2190 PHE 2191 0.0134

PHE 2191 ARG 2192 0.0425

ARG 2192 LEU 2193 0.0029

LEU 2193 MET 2194 0.0414

MET 2194 GLN 2195 0.0135

GLN 2195 ALA 2196 0.0312

ALA 2196 GLY 2197 0.0260

GLY 2197 LYS 2198 0.0179

LYS 2198 HIS 2199 0.0346

HIS 2199 MET 2200 0.0143

MET 2200 GLY 2201 0.0410

GLY 2201 LYS 2202 0.0280

LYS 2202 ILE 2203 0.0297

ILE 2203 VAL 2204 0.0425

VAL 2204 ILE 2205 0.1610

ILE 2205 THR 2206 0.0400

THR 2206 ALA 2207 0.0275

ALA 2207 PRO 2208 0.0375

PRO 2208 GLU 2209 0.0358

GLU 2209 ASP 2210 0.0363

ASP 2210 ALA 2211 0.0372

ALA 2211 MET 2212 0.0034

MET 2212 VAL 2213 0.0300

VAL 2213 PRO 2214 0.0041

PRO 2214 VAL 2215 0.0340

VAL 2215 ILE 2216 0.0048

ILE 2216 THR 2217 0.0362

THR 2217 ARG 2218 0.0297

ARG 2218 PRO 2219 0.0180

PRO 2219 PRO 2220 0.0434

PRO 2220 LYS 2221 0.2276

LYS 2221 LEU 2222 0.0177

LEU 2222 GLN 2223 0.0445

GLN 2223 LEU 2224 0.0211

LEU 2224 ARG 2225 0.0371

ARG 2225 PRO 2226 0.0416

PRO 2226 ASP 2227 0.0109

ASP 2227 ALA 2228 0.0330

ALA 2228 SER 2229 0.0436

SER 2229 TYR 2230 0.0444

TYR 2230 LEU 2231 0.0307

LEU 2231 ILE 2232 0.0390

ILE 2232 VAL 2233 0.0287

VAL 2233 GLY 2234 0.0322

GLY 2234 GLY 2235 0.0229

GLY 2235 LEU 2236 0.0396

LEU 2236 GLY 2237 0.0699

GLY 2237 GLY 2238 0.0099

GLY 2238 ILE 2239 0.0425

ILE 2239 GLY 2240 0.0330

GLY 2240 ARG 2241 0.0169

ARG 2241 SER 2242 0.0308

SER 2242 LEU 2243 0.0256

LEU 2243 CYS 2244 0.0448

CYS 2244 LYS 2245 0.0003

LYS 2245 ASN 2246 0.0446

ASN 2246 PHE 2247 0.0205

PHE 2247 VAL 2248 0.0358

VAL 2248 GLU 2249 0.0120

GLU 2249 ASN 2250 0.0334

ASN 2250 GLY 2251 0.0382

GLY 2251 ALA 2252 0.0167

ALA 2252 ARG 2253 0.0413

ARG 2253 SER 2254 0.0106

SER 2254 LEU 2255 0.0442

LEU 2255 VAL 2256 0.0141

VAL 2256 LEU 2257 0.0455

LEU 2257 LEU 2258 0.0146

LEU 2258 SER 2259 0.0461

SER 2259 ARG 2260 0.0266

ARG 2260 ASN 2261 0.0296

ASN 2261 ALA 2262 0.0385

ALA 2262 ASN 2263 0.0454

ASN 2263 VAL 2264 0.0166

VAL 2264 SER 2265 0.0345

SER 2265 GLN 2266 0.0272

GLN 2266 GLN 2267 0.0412

GLN 2267 SER 2268 0.0459

SER 2268 GLY 2269 0.0323

GLY 2269 GLU 2270 0.0062

GLU 2270 PHE 2271 0.0421

PHE 2271 LEU 2272 0.0256

LEU 2272 ASP 2273 0.0263

ASP 2273 GLU 2274 0.0286

GLU 2274 LEU 2275 0.0256

LEU 2275 ARG 2276 0.0441

ARG 2276 SER 2277 0.0031

SER 2277 THR 2278 0.0466

THR 2278 GLY 2279 0.0245

GLY 2279 CYS 2280 0.0228

CYS 2280 ILE 2281 0.0087

ILE 2281 VAL 2282 0.0436

VAL 2282 GLY 2283 0.0042

GLY 2283 VAL 2284 0.0457

VAL 2284 VAL 2285 -0.0391

VAL 2285 ASP 2286 0.0405

ASP 2286 CYS 2287 0.0308

CYS 2287 ASP 2288 0.0437

ASP 2288 ILE 2289 0.0475

ILE 2289 SER 2290 0.0299

SER 2290 SER 2291 0.0303

SER 2291 LYS 2292 0.0375

LYS 2292 THR 2293 0.0463

THR 2293 GLN 2294 0.0043

GLN 2294 VAL 2295 0.0446

VAL 2295 GLU 2296 0.0255

GLU 2296 ALA 2297 0.0461

ALA 2297 THR 2298 0.0027

THR 2298 MET 2299 0.0480

MET 2299 LEU 2300 0.0355

LEU 2300 ARG 2301 0.0074

ARG 2301 LEU 2302 0.0226

LEU 2302 LYS 2303 0.0388

LYS 2303 LYS 2304 0.0462

LYS 2304 ASP 2305 0.0114

ASP 2305 MET 2306 0.0341

MET 2306 LEU 2307 0.0444

LEU 2307 PRO 2308 0.0291

PRO 2308 ILE 2309 0.0466

ILE 2309 ARG 2310 0.0407

ARG 2310 GLY 2311 0.0443

GLY 2311 ILE 2312 0.0446

ILE 2312 VAL 2313 0.0372

VAL 2313 HIS 2314 0.0323

HIS 2314 ALA 2315 0.0297

ALA 2315 GLY 2316 0.0268

GLY 2316 MET 2317 0.2131

MET 2317 VAL 2318 0.0206

VAL 2318 LEU 2319 0.0211

LEU 2319 GLN 2320 0.0151

GLN 2320 ASP 2321 0.0203

ASP 2321 SER 2322 0.0134

SER 2322 VAL 2323 0.0196

VAL 2323 PHE 2324 0.0047

PHE 2324 GLU 2325 0.0169

GLU 2325 ARG 2326 0.0189

ARG 2326 MET 2327 0.0220

MET 2327 SER 2328 0.0135

SER 2328 LEU 2329 0.0146

LEU 2329 ASP 2330 0.0152

ASP 2330 ASP 2331 0.0063

ASP 2331 TYR 2332 0.0185

TYR 2332 ASN 2333 0.1033

ASN 2333 THR 2334 0.0078

THR 2334 ALA 2335 0.0234

ALA 2335 ILE 2336 0.0193

ILE 2336 ARG 2337 0.0305

ARG 2337 PRO 2338 0.0102

PRO 2338 LYS 2339 0.0322

LYS 2339 VAL 2340 0.0007

VAL 2340 GLN 2341 0.0262

GLN 2341 GLY 2342 0.0092

GLY 2342 SER 2343 0.0311

SER 2343 TRP 2344 0.0023

TRP 2344 ASN 2345 0.0320

ASN 2345 LEU 2346 0.0105

LEU 2346 HIS 2347 0.0257

HIS 2347 SER 2348 0.0118

SER 2348 GLY 2349 0.0053

GLY 2349 LEU 2350 0.0274

LEU 2350 SER 2351 0.0235

SER 2351 ASP 2352 0.0433

ASP 2352 CYS 2353 0.0002

CYS 2353 ASP 2354 0.0341

ASP 2354 LEU 2355 0.0217

LEU 2355 ASP 2356 0.0137

ASP 2356 PHE 2357 0.0427

PHE 2357 PHE 2358 0.0349

PHE 2358 ILE 2359 0.0283

ILE 2359 MET 2360 0.0405

MET 2360 LEU 2361 0.0212

LEU 2361 SER 2362 0.0343

SER 2362 SER 2363 0.0337

SER 2363 LEU 2364 0.0383

LEU 2364 ALA 2365 0.0310

ALA 2365 GLY 2366 0.0066

GLY 2366 VAL 2367 0.0218

VAL 2367 SER 2368 0.0184

SER 2368 GLY 2369 0.0167

GLY 2369 SER 2370 0.0159

SER 2370 ALA 2371 0.0206

ALA 2371 SER 2372 0.0210

SER 2372 GLN 2373 0.0222

GLN 2373 ALA 2374 0.0018

ALA 2374 ASN 2375 0.0219

ASN 2375 TYR 2376 0.0070

TYR 2376 THR 2377 0.0212

THR 2377 ALA 2378 0.0037

ALA 2378 GLY 2379 0.0180

GLY 2379 GLY 2380 0.0141

GLY 2380 ALA 2381 -0.0041

ALA 2381 TYR 2382 0.0223

TYR 2382 GLN 2383 0.0187

GLN 2383 ASP 2384 0.0345

ASP 2384 ALA 2385 0.0018

ALA 2385 LEU 2386 0.0351

LEU 2386 ALA 2387 0.0163

ALA 2387 LYS 2388 0.0267

LYS 2388 TYR 2389 0.0106

TYR 2389 ARG 2390 0.0291

ARG 2390 ARG 2391 0.0295

ARG 2391 ALA 2392 0.0080

ALA 2392 GLN 2393 0.0309

GLN 2393 GLY 2394 0.0171

GLY 2394 LEU 2395 0.0280

LEU 2395 SER 2396 0.0020

SER 2396 ALA 2397 0.0109

ALA 2397 VAL 2398 0.0188

VAL 2398 SER 2399 0.0363

SER 2399 ILE 2400 0.0060

ILE 2400 ASP 2401 0.0362

ASP 2401 LEU 2402 0.0104

LEU 2402 GLY 2403 0.0242

GLY 2403 MET 2404 0.0226

MET 2404 VAL 2405 0.0250

VAL 2405 GLN 2406 0.0068

GLN 2406 SER 2407 0.0308

SER 2407 VAL 2408 0.0143

VAL 2408 GLY 2409 0.0088

GLY 2409 TYR 2410 0.0302

TYR 2410 VAL 2411 0.0252

VAL 2411 ALA 2412 0.0106

ALA 2412 GLU 2413 0.0242

GLU 2413 THR 2414 0.0324

THR 2414 LYS 2415 0.0222

LYS 2415 GLY 2416 0.0347

GLY 2416 VAL 2417 0.0176

VAL 2417 ALA 2418 0.0259

ALA 2418 GLU 2419 0.0329

GLU 2419 ARG 2420 0.0050

ARG 2420 LEU 2421 0.0322

LEU 2421 VAL 2422 0.0178

VAL 2422 ARG 2423 0.0349

ARG 2423 MET 2424 0.0030

MET 2424 GLY 2425 0.0344

GLY 2425 TYR 2426 0.0367

TYR 2426 SER 2427 0.0174

SER 2427 PRO 2428 0.0282

PRO 2428 ILE 2429 0.0833

ILE 2429 SER 2430 0.0181

SER 2430 GLU 2431 0.0352

GLU 2431 MET 2432 0.0305

MET 2432 GLU 2433 0.0234

GLU 2433 VAL 2434 0.0145

VAL 2434 LEU 2435 0.0330

LEU 2435 LYS 2436 0.0355

LYS 2436 ILE 2437 0.0061

ILE 2437 VAL 2438 0.0311

VAL 2438 GLU 2439 0.0255

GLU 2439 HIS 2440 0.0333

HIS 2440 ALA 2441 0.0035

ALA 2441 ILE 2442 0.0358

ILE 2442 THR 2443 0.0275

THR 2443 ASN 2444 0.0288

ASN 2444 PRO 2445 0.0848

PRO 2445 PRO 2446 0.0345

PRO 2446 PRO 2447 0.0237

PRO 2447 GLU 2448 0.0233

GLU 2448 ALA 2449 0.0306

ALA 2449 SER 2450 0.0347

SER 2450 SER 2451 0.0053

SER 2451 ALA 2452 0.0386

ALA 2452 GLN 2453 0.0298

GLN 2453 ILE 2454 0.0002

ILE 2454 ILE 2455 0.0341

ILE 2455 THR 2456 0.0058

THR 2456 GLY 2457 0.0219

GLY 2457 ILE 2458 0.0395

ILE 2458 SER 2459 0.0112

SER 2459 THR 2460 0.0388

THR 2460 LYS 2461 -0.0440

LYS 2461 PRO 2462 0.0309

PRO 2462 GLY 2463 0.0309

GLY 2463 ARG 2464 0.0278

ARG 2464 HIS 2465 0.0173

HIS 2465 TRP 2466 0.0219

TRP 2466 THR 2467 0.0311

THR 2467 GLU 2468 0.0311

GLU 2468 SER 2469 0.0212

SER 2469 SER 2470 0.0029

SER 2470 TRP 2471 0.0272

TRP 2471 LEU 2472 0.0236

LEU 2472 GLN 2473 0.0222

GLN 2473 ASP 2474 0.0101

ASP 2474 ALA 2475 0.0269

ALA 2475 ARG 2476 0.0309

ARG 2476 PHE 2477 -0.0354

PHE 2477 ALA 2478 0.0259

ALA 2478 THR 2479 0.0287

THR 2479 LEU 2480 0.0022

LEU 2480 ARG 2481 0.0279

ARG 2481 GLU 2482 0.0270

GLU 2482 ARG 2483 0.0201

ARG 2483 ALA 2484 0.0127

ALA 2484 ARG 2485 0.0275

ARG 2485 ASP 2486 0.0287

ASP 2486 VAL 2487 0.0049

VAL 2487 LYS 2488 0.0269

LYS 2488 GLU 2489 0.0240

GLU 2489 LEU 2490 0.0263

LEU 2490 SER 2491 0.0052

SER 2491 ASN 2492 0.0284

ASN 2492 SER 2493 0.0312

SER 2493 GLN 2494 0.0386

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** sdgklnrdh ***

CA strain for 22101813491974862

--- normal mode 15 ---

Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *