Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *

CA strain for 22101813491974862

--- normal mode 13 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
ASN 989 LYS 990 0.0106

LYS 990 ALA 991 0.0137

ALA 991 HIS 992 0.0133

HIS 992 ARG 993 0.0077

ARG 993 GLN 994 0.0131

GLN 994 ARG 995 0.0141

ARG 995 VAL 996 0.0056

VAL 996 HIS 997 0.0134

HIS 997 PRO 998 0.0139

PRO 998 PRO 999 0.0109

PRO 999 HIS 1000 0.0118

HIS 1000 ASP 1001 0.0132

ASP 1001 LEU 1002 0.0109

LEU 1002 LEU 1003 0.0071

LEU 1003 GLY 1004 0.0135

GLY 1004 SER 1005 0.0190

SER 1005 LEU 1006 0.0077

LEU 1006 ILE 1007 0.0006

ILE 1007 VAL 1008 0.0094

VAL 1008 GLY 1009 0.0039

GLY 1009 ARG 1010 0.0099

ARG 1010 ASP 1011 0.0097

ASP 1011 LEU 1012 0.0004

LEU 1012 ARG 1013 0.0093

ARG 1013 GLU 1014 0.0092

GLU 1014 PRO 1015 0.0066

PRO 1015 THR 1016 0.0098

THR 1016 TRP 1017 0.0057

TRP 1017 ARG 1018 0.0093

ARG 1018 HIS 1019 0.0061

HIS 1019 PHE 1020 0.0098

PHE 1020 ILE 1021 0.0086

ILE 1021 ARG 1022 0.0151

ARG 1022 VAL 1023 0.0095

VAL 1023 GLN 1024 0.0132

GLN 1024 ASP 1025 0.0178

ASP 1025 ILE 1026 0.0175

ILE 1026 PRO 1027 0.0139

PRO 1027 TRP 1028 0.0172

TRP 1028 ILE 1029 0.0015

ILE 1029 ARG 1030 0.0175

ARG 1030 ASP 1031 0.0127

ASP 1031 HIS 1032 0.0074

HIS 1032 VAL 1033 0.0118

VAL 1033 VAL 1034 0.0101

VAL 1034 GLN 1035 0.0137

GLN 1035 SER 1036 0.0159

SER 1036 ALA 1037 0.0836

ALA 1037 LEU 1038 0.0088

LEU 1038 VAL 1039 0.0114

VAL 1039 TYR 1040 0.0114

TYR 1040 PRO 1041 0.0098

PRO 1041 GLY 1042 0.0089

GLY 1042 ALA 1043 0.0042

ALA 1043 GLY 1044 0.0121

GLY 1044 PHE 1045 0.0030

PHE 1045 ILE 1046 0.0094

ILE 1046 CYS 1047 0.0059

CYS 1047 MET 1048 0.0063

MET 1048 ALA 1049 0.0104

ALA 1049 MET 1050 0.0024

MET 1050 GLU 1051 0.0119

GLU 1051 ALA 1052 0.0019

ALA 1052 MET 1053 -0.0006

MET 1053 VAL 1054 0.0034

VAL 1054 GLN 1055 0.0115

GLN 1055 LEU 1056 0.0078

LEU 1056 HIS 1057 0.0067

HIS 1057 GLU 1058 0.0110

GLU 1058 LEU 1059 0.0044

LEU 1059 ARG 1060 0.0139

ARG 1060 ASP 1061 0.0045

ASP 1061 SER 1062 0.0092

SER 1062 GLN 1063 0.0117

GLN 1063 SER 1064 0.0077

SER 1064 ARG 1065 0.0137

ARG 1065 LYS 1066 0.0096

LYS 1066 VAL 1067 0.0107

VAL 1067 ALA 1068 0.0133

ALA 1068 GLY 1069 -0.0065

GLY 1069 TYR 1070 0.0032

TYR 1070 ARG 1071 0.0058

ARG 1071 LEU 1072 0.0059

LEU 1072 ALA 1073 0.0050

ALA 1073 GLU 1074 0.0051

GLU 1074 VAL 1075 0.0092

VAL 1075 ASP 1076 0.0071

ASP 1076 ILE 1077 0.0100

ILE 1077 LEU 1078 0.0018

LEU 1078 ARG 1079 0.0102

ARG 1079 ALA 1080 0.0039

ALA 1080 MET 1081 0.0104

MET 1081 LEU 1082 0.0105

LEU 1082 ILE 1083 0.0067

ILE 1083 PRO 1084 0.0103

PRO 1084 ASP 1085 0.0138

ASP 1085 THR 1086 0.0079

THR 1086 SER 1087 0.0091

SER 1087 GLU 1088 0.0048

GLU 1088 GLY 1089 0.0087

GLY 1089 LEU 1090 0.0072

LEU 1090 GLU 1091 0.0086

GLU 1091 ALA 1092 0.0090

ALA 1092 HIS 1093 0.0091

HIS 1093 ILE 1094 0.0085

ILE 1094 SER 1095 0.0070

SER 1095 LEU 1096 0.0088

LEU 1096 ARG 1097 0.0053

ARG 1097 PRO 1098 0.0093

PRO 1098 CYS 1099 0.0089

CYS 1099 SER 1100 0.0045

SER 1100 THR 1101 0.0152

THR 1101 LYS 1102 0.0037

LYS 1102 LEU 1103 0.0023

LEU 1103 LEU 1104 0.0054

LEU 1104 LEU 1105 0.0013

LEU 1105 THR 1106 0.0046

THR 1106 ASN 1107 0.0051

ASN 1107 GLU 1108 0.0059

GLU 1108 TRP 1109 0.0063

TRP 1109 TYR 1110 0.0059

TYR 1110 ASP 1111 0.0051

ASP 1111 PHE 1112 0.0048

PHE 1112 CYS 1113 0.0057

CYS 1113 VAL 1114 0.0043

VAL 1114 SER 1115 0.0046

SER 1115 SER 1116 0.0062

SER 1116 VAL 1117 0.0108

VAL 1117 GLY 1118 0.0076

GLY 1118 ASP 1119 0.0068

ASP 1119 ASP 1120 0.0012

ASP 1120 ASP 1121 0.0076

ASP 1121 LYS 1122 0.0081

LYS 1122 PHE 1123 0.0048

PHE 1123 VAL 1124 0.0059

VAL 1124 ASP 1125 0.0063

ASP 1125 HIS 1126 0.0013

HIS 1126 CYS 1127 0.0072

CYS 1127 ARG 1128 0.0068

ARG 1128 GLY 1129 0.0066

GLY 1129 ARG 1130 0.0075

ARG 1130 ILE 1131 0.0035

ILE 1131 THR 1132 0.0071

THR 1132 ILE 1133 -0.0270

ILE 1133 GLU 1134 0.0129

GLU 1134 PHE 1135 0.0082

PHE 1135 ASP 1136 0.0084

ASP 1136 THR 1137 0.0104

THR 1137 SER 1138 0.0085

SER 1138 GLY 1139 0.0104

GLY 1139 SER 1140 0.0115

SER 1140 ALA 1141 0.0094

ALA 1141 ASP 1142 0.0136

ASP 1142 THR 1143 0.0030

THR 1143 PRO 1144 0.0094

PRO 1144 ARG 1145 0.0133

ARG 1145 THR 1146 0.0138

THR 1146 SER 1147 0.0038

SER 1147 LEU 1148 0.0133

LEU 1148 ARG 1149 0.0909

ARG 1149 GLU 1150 0.0067

GLU 1150 ARG 1151 0.0206

ARG 1151 SER 1152 0.0037

SER 1152 ARG 1153 0.0210

ARG 1153 SER 1154 0.0206

SER 1154 THR 1155 0.0141

THR 1155 GLY 1156 0.0171

GLY 1156 LEU 1157 0.0038

LEU 1157 MET 1158 0.0206

MET 1158 ARG 1159 0.0153

ARG 1159 SER 1160 0.0139

SER 1160 VAL 1161 0.0212

VAL 1161 ASP 1162 0.0140

ASP 1162 PRO 1163 0.0152

PRO 1163 SER 1164 0.0153

SER 1164 ASN 1165 0.0866

ASN 1165 LEU 1166 0.0092

LEU 1166 TYR 1167 0.0207

TYR 1167 SER 1168 0.0208

SER 1168 PHE 1169 0.0103

PHE 1169 LEU 1170 0.0140

LEU 1170 ARG 1171 0.0206

ARG 1171 ALA 1172 0.0188

ALA 1172 GLN 1173 0.0078

GLN 1173 GLY 1174 0.0201

GLY 1174 ILE 1175 0.0169

ILE 1175 TYR 1176 0.0098

TYR 1176 HIS 1177 0.0136

HIS 1177 GLY 1178 0.0129

GLY 1178 PRO 1179 0.0028

PRO 1179 ILE 1180 0.0194

ILE 1180 PHE 1181 -0.0592

PHE 1181 GLN 1182 0.0090

GLN 1182 ASN 1183 0.0145

ASN 1183 LEU 1184 0.0157

LEU 1184 LYS 1185 0.0031

LYS 1185 THR 1186 0.0152

THR 1186 ILE 1187 0.0068

ILE 1187 SER 1188 0.0156

SER 1188 SER 1189 0.0043

SER 1189 ARG 1190 0.0119

ARG 1190 LYS 1191 0.0028

LYS 1191 ASP 1192 0.0119

ASP 1192 HIS 1193 0.0087

HIS 1193 SER 1194 0.0068

SER 1194 GLU 1195 0.0079

GLU 1195 SER 1196 0.0148

SER 1196 SER 1197 0.0282

SER 1197 PHE 1198 0.0173

PHE 1198 VAL 1199 0.0140

VAL 1199 VAL 1200 0.0153

VAL 1200 ALA 1201 0.0176

ALA 1201 ASN 1202 0.0145

ASN 1202 THR 1203 0.0041

THR 1203 ALA 1204 0.0154

ALA 1204 SER 1205 0.0108

SER 1205 VAL 1206 0.0076

VAL 1206 MET 1207 0.0136

MET 1207 PRO 1208 0.0174

PRO 1208 ASN 1209 0.0058

ASN 1209 GLY 1210 0.0174

GLY 1210 PHE 1211 0.0093

PHE 1211 GLN 1212 0.0105

GLN 1212 SER 1213 0.0118

SER 1213 PRO 1214 0.0163

PRO 1214 HIS 1215 0.0128

HIS 1215 VAL 1216 0.0176

VAL 1216 ILE 1217 0.0176

ILE 1217 HIS 1218 0.0177

HIS 1218 PRO 1219 0.0098

PRO 1219 THR 1220 0.0080

THR 1220 THR 1221 0.0152

THR 1221 LEU 1222 0.0039

LEU 1222 ASP 1223 0.0167

ASP 1223 SER 1224 0.0043

SER 1224 ILE 1225 0.0157

ILE 1225 PHE 1226 0.0047

PHE 1226 GLN 1227 0.0126

GLN 1227 GLY 1228 0.0138

GLY 1228 ALA 1229 0.0342

ALA 1229 TYR 1230 0.0126

TYR 1230 THR 1231 0.0032

THR 1231 ALA 1232 0.0102

ALA 1232 LEU 1233 0.0102

LEU 1233 PRO 1234 0.0114

PRO 1234 GLY 1235 0.0055

GLY 1235 ALA 1236 0.0130

ALA 1236 GLY 1237 0.0049

GLY 1237 LEU 1238 0.0105

LEU 1238 ASP 1239 0.0072

ASP 1239 GLN 1240 0.0041

GLN 1240 ASN 1241 0.0069

ASN 1241 THR 1242 0.0108

THR 1242 ALA 1243 0.0124

ALA 1243 MET 1244 0.0122

MET 1244 ILE 1245 0.1194

ILE 1245 PRO 1246 0.0126

PRO 1246 ARG 1247 0.0008

ARG 1247 SER 1248 0.0126

SER 1248 ILE 1249 0.0088

ILE 1249 GLN 1250 0.0111

GLN 1250 GLU 1251 0.0066

GLU 1251 LEU 1252 0.0045

LEU 1252 TYR 1253 0.0076

TYR 1253 LEU 1254 0.0056

LEU 1254 SER 1255 0.0069

SER 1255 SER 1256 0.0114

SER 1256 ALA 1257 0.0025

ALA 1257 LEU 1258 0.0128

LEU 1258 THR 1259 0.0076

THR 1259 SER 1260 0.0123

SER 1260 ASP 1261 -0.0030

ASP 1261 VAL 1262 0.0151

VAL 1262 GLY 1263 0.0134

GLY 1263 GLN 1264 0.0147

GLN 1264 CYS 1265 0.0154

CYS 1265 LEU 1266 0.0040

LEU 1266 VAL 1267 0.0149

VAL 1267 SER 1268 0.0017

SER 1268 ASP 1269 0.0138

ASP 1269 THR 1270 0.0047

THR 1270 SER 1271 0.0093

SER 1271 LEU 1272 0.0079

LEU 1272 ILE 1273 0.0033

ILE 1273 ARG 1274 0.0112

ARG 1274 TYR 1275 0.0159

TYR 1275 ASP 1276 0.0083

ASP 1276 GLY 1277 0.0168

GLY 1277 GLN 1278 0.0089

GLN 1278 SER 1279 0.0129

SER 1279 PHE 1280 0.0075

PHE 1280 THR 1281 0.0132

THR 1281 VAL 1282 0.0038

VAL 1282 ASN 1283 0.0117

ASN 1283 VAL 1284 0.0048

VAL 1284 ASP 1285 0.0079

ASP 1285 VAL 1286 0.0067

VAL 1286 SER 1287 0.0043

SER 1287 SER 1288 0.0043

SER 1288 LYS 1289 0.0052

LYS 1289 ALA 1290 0.0089

ALA 1290 ASP 1291 0.0091

ASP 1291 SER 1292 0.0113

SER 1292 GLU 1293 0.0129

GLU 1293 HIS 1294 0.0093

HIS 1294 THR 1295 0.0054

THR 1295 PRO 1296 0.0057

PRO 1296 VAL 1297 0.0124

VAL 1297 LEU 1298 0.0052

LEU 1298 GLU 1299 0.0074

GLU 1299 ILE 1300 0.0065

ILE 1300 LYS 1301 0.0068

LYS 1301 GLY 1302 0.0082

GLY 1302 LEU 1303 0.0109

LEU 1303 ARG 1304 0.0078

ARG 1304 ASN 1305 0.0115

ASN 1305 GLN 1306 0.0067

GLN 1306 SER 1307 0.0125

SER 1307 VAL 1308 0.0117

VAL 1308 GLY 1309 0.2224

GLY 1309 GLN 1310 0.0471

GLN 1310 MET 1311 0.0082

MET 1311 ALA 1312 0.0462

ALA 1312 PRO 1313 0.0487

PRO 1313 GLN 1314 0.0035

GLN 1314 PRO 1315 0.0442

PRO 1315 GLY 1316 0.0460

GLY 1316 ASP 1317 0.0207

ASP 1317 SER 1318 0.0279

SER 1318 SER 1319 0.0210

SER 1319 ASN 1320 0.0487

ASN 1320 ASN 1321 0.0270

ASN 1321 ASP 1322 0.0476

ASP 1322 LEU 1323 0.0309

LEU 1323 CYS 1324 0.0412

CYS 1324 PHE 1325 0.0348

PHE 1325 LYS 1326 0.0196

LYS 1326 LEU 1327 0.0212

LEU 1327 ASP 1328 0.0036

ASP 1328 TRP 1329 0.0208

TRP 1329 ALA 1330 0.0053

ALA 1330 PRO 1331 0.0190

PRO 1331 ASP 1332 0.0203

ASP 1332 ILE 1333 0.0029

ILE 1333 SER 1334 0.0188

SER 1334 SER 1335 0.0204

SER 1335 VAL 1336 0.0091

VAL 1336 LYS 1337 0.0150

LYS 1337 GLN 1338 0.0000

GLN 1338 GLU 1339 0.0207

GLU 1339 ARG 1340 0.0151

ARG 1340 LEU 1341 0.0172

LEU 1341 LYS 1342 0.0023

LYS 1342 GLU 1343 0.0422

GLU 1343 LYS 1344 0.0308

LYS 1344 PHE 1345 0.0428

PHE 1345 GLY 1346 0.0097

GLY 1346 PHE 1347 0.0170

PHE 1347 PRO 1348 0.0068

PRO 1348 LEU 1349 0.0197

LEU 1349 ASP 1350 0.0375

ASP 1350 PRO 1351 0.0003

PRO 1351 THR 1352 0.0437

THR 1352 GLU 1353 0.0273

GLU 1353 ALA 1354 0.0325

ALA 1354 ASP 1355 0.0165

ASP 1355 ILE 1356 0.0319

ILE 1356 ILE 1357 0.0596

ILE 1357 MET 1358 0.0075

MET 1358 GLY 1359 0.0471

GLY 1359 LEU 1360 0.0221

LEU 1360 ARG 1361 0.0485

ARG 1361 GLN 1362 0.0060

GLN 1362 ALA 1363 0.0472

ALA 1363 CYS 1364 0.0344

CYS 1364 ILE 1365 0.0231

ILE 1365 HIS 1366 0.0354

HIS 1366 PHE 1367 0.0271

PHE 1367 ILE 1368 0.0500

ILE 1368 HIS 1369 0.0030

HIS 1369 ARG 1370 0.0502

ARG 1370 SER 1371 0.0200

SER 1371 LEU 1372 0.0488

LEU 1372 GLN 1373 0.0106

GLN 1373 SER 1374 0.0476

SER 1374 LEU 1375 0.0264

LEU 1375 THR 1376 0.0470

THR 1376 ALA 1377 0.0470

ALA 1377 PRO 1378 0.0354

PRO 1378 ASP 1379 0.0455

ASP 1379 ARG 1380 0.0491

ARG 1380 ASP 1381 0.0419

ASP 1381 GLN 1382 0.0365

GLN 1382 LEU 1383 0.0475

LEU 1383 ASP 1384 0.0007

ASP 1384 TRP 1385 0.0460

TRP 1385 HIS 1386 0.0521

HIS 1386 GLN 1387 0.0094

GLN 1387 LYS 1388 0.0467

LYS 1388 ARG 1389 0.0291

ARG 1389 PHE 1390 0.0417

PHE 1390 TYR 1391 0.0141

TYR 1391 ASP 1392 0.0501

ASP 1392 TRP 1393 0.0486

TRP 1393 MET 1394 0.0208

MET 1394 VAL 1395 0.0331

VAL 1395 LEU 1396 0.0447

LEU 1396 GLN 1397 0.0487

GLN 1397 ILE 1398 0.0052

ILE 1398 GLN 1399 0.0501

GLN 1399 LEU 1400 0.0430

LEU 1400 ALA 1401 0.0307

ALA 1401 GLU 1402 0.0215

GLU 1402 GLU 1403 0.0454

GLU 1403 ASP 1404 0.0503

ASP 1404 ARG 1405 -0.0049

ARG 1405 LEU 1406 0.0445

LEU 1406 ALA 1407 0.0407

ALA 1407 PRO 1408 0.0162

PRO 1408 ASN 1409 0.0228

ASN 1409 SER 1410 0.0344

SER 1410 SER 1411 0.0268

SER 1411 ALA 1412 0.0376

ALA 1412 TRP 1413 0.0255

TRP 1413 LEU 1414 0.0477

LEU 1414 GLN 1415 0.0089

GLN 1415 CYS 1416 0.0489

CYS 1416 SER 1417 0.0369

SER 1417 SER 1418 0.0407

SER 1418 SER 1419 0.0512

SER 1419 ASP 1420 0.0437

ASP 1420 GLU 1421 0.0270

GLU 1421 GLN 1422 0.0495

GLN 1422 LYS 1423 0.0518

LYS 1423 LEU 1424 0.0354

LEU 1424 LEU 1425 0.0307

LEU 1425 GLU 1426 0.0518

GLU 1426 ASN 1427 0.0507

ASN 1427 VAL 1428 0.0274

VAL 1428 ARG 1429 0.0414

ARG 1429 ALA 1430 0.0517

ALA 1430 SER 1431 0.0480

SER 1431 SER 1432 0.0106

SER 1432 VAL 1433 0.0285

VAL 1433 ASN 1434 0.0484

ASN 1434 GLY 1435 0.0068

GLY 1435 GLN 1436 0.0459

GLN 1436 MET 1437 0.0319

MET 1437 VAL 1438 0.0246

VAL 1438 VAL 1439 0.0282

VAL 1439 HIS 1440 0.0325

HIS 1440 VAL 1441 0.0479

VAL 1441 GLY 1442 0.0116

GLY 1442 LYS 1443 0.0378

LYS 1443 SER 1444 0.0333

SER 1444 MET 1445 0.0509

MET 1445 LEU 1446 0.0338

LEU 1446 ALA 1447 0.0386

ALA 1447 ILE 1448 0.0144

ILE 1448 LEU 1449 0.0452

LEU 1449 ARG 1450 0.0480

ARG 1450 HIS 1451 0.0077

HIS 1451 GLU 1452 0.0448

GLU 1452 ILE 1453 0.0951

ILE 1453 ALA 1454 0.0120

ALA 1454 PRO 1455 0.0493

PRO 1455 LEU 1456 0.0097

LEU 1456 GLU 1457 0.0493

GLU 1457 LEU 1458 0.0103

LEU 1458 MET 1459 0.0419

MET 1459 LEU 1460 0.0231

LEU 1460 GLN 1461 0.0297

GLN 1461 ASP 1462 0.0499

ASP 1462 LYS 1463 0.0236

LYS 1463 LEU 1464 0.0243

LEU 1464 LEU 1465 0.0326

LEU 1465 TYR 1466 0.0269

TYR 1466 ARG 1467 0.0255

ARG 1467 TYR 1468 0.0447

TYR 1468 TYR 1469 0.0656

TYR 1469 THR 1470 0.0419

THR 1470 ASP 1471 0.0088

ASP 1471 ALA 1472 0.0287

ALA 1472 ILE 1473 0.0365

ILE 1473 LYS 1474 0.0286

LYS 1474 TRP 1475 0.0122

TRP 1475 ASP 1476 0.0383

ASP 1476 ARG 1477 0.0425

ARG 1477 SER 1478 0.0310

SER 1478 TYR 1479 0.0235

TYR 1479 GLN 1480 0.0427

GLN 1480 GLN 1481 0.0416

GLN 1481 ILE 1482 0.0216

ILE 1482 ASP 1483 0.0365

ASP 1483 GLN 1484 0.0422

GLN 1484 LEU 1485 0.0794

LEU 1485 VAL 1486 0.0251

VAL 1486 LYS 1487 0.0279

LYS 1487 LEU 1488 0.0292

LEU 1488 HIS 1489 0.0298

HIS 1489 ALA 1490 0.0268

ALA 1490 HIS 1491 0.0267

HIS 1491 LYS 1492 0.0286

LYS 1492 CYS 1493 0.0315

CYS 1493 PRO 1494 0.0327

PRO 1494 THR 1495 0.0280

THR 1495 ALA 1496 0.0135

ALA 1496 LYS 1497 0.0313

LYS 1497 ILE 1498 0.0003

ILE 1498 ILE 1499 0.0178

ILE 1499 GLU 1500 0.0015

GLU 1500 ILE 1501 0.0460

ILE 1501 GLY 1502 0.0118

GLY 1502 ALA 1503 0.0345

ALA 1503 GLY 1504 0.0172

GLY 1504 THR 1505 0.0306

THR 1505 GLY 1506 0.0202

GLY 1506 GLY 1507 0.0207

GLY 1507 CYS 1508 0.0214

CYS 1508 THR 1509 0.0126

THR 1509 ARG 1510 0.0326

ARG 1510 ALA 1511 0.0346

ALA 1511 VAL 1512 0.0100

VAL 1512 LEU 1513 0.0268

LEU 1513 ASP 1514 0.0305

ASP 1514 ALA 1515 0.0309

ALA 1515 LEU 1516 0.0086

LEU 1516 SER 1517 0.0833

SER 1517 ASN 1518 0.0310

ASN 1518 GLN 1519 0.0347

GLN 1519 GLY 1520 0.0366

GLY 1520 ILE 1521 0.0135

ILE 1521 ALA 1522 0.0360

ALA 1522 ARG 1523 0.0312

ARG 1523 CYS 1524 0.0366

CYS 1524 ALA 1525 0.0232

ALA 1525 GLN 1526 0.0170

GLN 1526 TYR 1527 0.0005

TYR 1527 ASP 1528 0.0314

ASP 1528 PHE 1529 0.0027

PHE 1529 THR 1530 0.0303

THR 1530 ASP 1531 0.0074

ASP 1531 VAL 1532 0.0322

VAL 1532 SER 1533 0.0234

SER 1533 SER 1534 0.0246

SER 1534 GLY 1535 0.0086

GLY 1535 PHE 1536 0.0328

PHE 1536 PHE 1537 0.0017

PHE 1537 GLU 1538 0.0331

GLU 1538 ALA 1539 0.0187

ALA 1539 ALA 1540 0.0228

ALA 1540 GLN 1541 0.0106

GLN 1541 GLN 1542 0.0259

GLN 1542 LYS 1543 0.0291

LYS 1543 PHE 1544 0.0078

PHE 1544 ALA 1545 0.0201

ALA 1545 ALA 1546 0.0294

ALA 1546 PHE 1547 0.0283

PHE 1547 ASP 1548 0.0300

ASP 1548 ASP 1549 0.0637

ASP 1549 VAL 1550 0.0305

VAL 1550 ILE 1551 0.0118

ILE 1551 ARG 1552 0.0317

ARG 1552 PHE 1553 0.0114

PHE 1553 GLN 1554 0.0318

GLN 1554 LYS 1555 0.0186

LYS 1555 LEU 1556 0.0321

LEU 1556 ASP 1557 0.0221

ASP 1557 ILE 1558 0.0309

ILE 1558 GLU 1559 0.0286

GLU 1559 LYS 1560 0.0154

LYS 1560 ASP 1561 0.0016

ASP 1561 ILE 1562 0.0267

ILE 1562 GLU 1563 0.0064

GLU 1563 MET 1564 0.0254

MET 1564 GLN 1565 0.0060

GLN 1565 GLY 1566 0.0090

GLY 1566 PHE 1567 0.0319

PHE 1567 GLU 1568 0.0168

GLU 1568 CYS 1569 0.0302

CYS 1569 GLY 1570 0.0323

GLY 1570 SER 1571 0.0310

SER 1571 TYR 1572 0.0128

TYR 1572 ASP 1573 0.0322

ASP 1573 LEU 1574 0.0025

LEU 1574 VAL 1575 0.0178

VAL 1575 ILE 1576 0.0094

ILE 1576 ALA 1577 0.0110

ALA 1577 SER 1578 0.0086

SER 1578 GLN 1579 0.0109

GLN 1579 VAL 1580 0.0248

VAL 1580 LEU 1581 0.0813

LEU 1581 HIS 1582 0.0040

HIS 1582 ALA 1583 0.0349

ALA 1583 THR 1584 0.0216

THR 1584 GLY 1585 0.0344

GLY 1585 LYS 1586 0.0288

LYS 1586 MET 1587 0.0343

MET 1587 GLU 1588 0.0175

GLU 1588 HIS 1589 0.0248

HIS 1589 THR 1590 0.0343

THR 1590 MET 1591 0.0330

MET 1591 ALA 1592 0.0120

ALA 1592 ASN 1593 0.0324

ASN 1593 VAL 1594 0.0332

VAL 1594 ARG 1595 0.0241

ARG 1595 LYS 1596 0.0138

LYS 1596 LEU 1597 0.0156

LEU 1597 LEU 1598 0.0350

LEU 1598 LYS 1599 0.0104

LYS 1599 PRO 1600 0.0357

PRO 1600 GLY 1601 0.0266

GLY 1601 GLY 1602 0.0312

GLY 1602 LYS 1603 0.0042

LYS 1603 LEU 1604 0.0131

LEU 1604 LEU 1605 0.0176

LEU 1605 LEU 1606 0.0089

LEU 1606 VAL 1607 0.0093

VAL 1607 GLU 1608 0.0199

GLU 1608 THR 1609 0.0010

THR 1609 THR 1610 0.0350

THR 1610 ARG 1611 -0.0000

ARG 1611 ASP 1612 0.0274

ASP 1612 GLU 1613 -0.0505

GLU 1613 MET 1614 0.0274

MET 1614 ASP 1615 0.0474

ASP 1615 LEU 1616 0.0029

LEU 1616 GLN 1617 0.0478

GLN 1617 LEU 1618 0.0274

LEU 1618 VAL 1619 0.0314

VAL 1619 PHE 1620 0.0152

PHE 1620 GLY 1621 0.0413

GLY 1621 LEU 1622 0.0490

LEU 1622 LEU 1623 0.0004

LEU 1623 PRO 1624 0.0379

PRO 1624 GLY 1625 0.0266

GLY 1625 TRP 1626 0.0271

TRP 1626 TRP 1627 0.0490

TRP 1627 LEU 1628 0.0056

LEU 1628 SER 1629 0.0167

SER 1629 SER 1630 0.0473

SER 1630 GLU 1631 0.0462

GLU 1631 GLU 1632 0.0096

GLU 1632 GLU 1633 0.0463

GLU 1633 ARG 1634 0.0455

ARG 1634 GLN 1635 0.0342

GLN 1635 MET 1636 0.0199

MET 1636 SER 1637 0.0318

SER 1637 PRO 1638 0.0043

PRO 1638 SER 1639 0.0471

SER 1639 LEU 1640 0.0430

LEU 1640 SER 1641 0.0411

SER 1641 THR 1642 0.0292

THR 1642 ASN 1643 0.0474

ASN 1643 SER 1644 0.0437

SER 1644 TRP 1645 -0.0013

TRP 1645 GLU 1646 0.0345

GLU 1646 LYS 1647 0.0424

LYS 1647 VAL 1648 0.0386

VAL 1648 LEU 1649 0.0248

LEU 1649 LYS 1650 0.0371

LYS 1650 LYS 1651 0.0427

LYS 1651 THR 1652 0.0346

THR 1652 GLY 1653 0.0188

GLY 1653 PHE 1654 0.0357

PHE 1654 ASP 1655 0.0428

ASP 1655 GLY 1656 0.0010

GLY 1656 LEU 1657 0.0304

LEU 1657 ASP 1658 0.0337

ASP 1658 ILE 1659 0.0184

ILE 1659 GLU 1660 0.0043

GLU 1660 LEU 1661 0.0240

LEU 1661 ARG 1662 0.0058

ARG 1662 ASP 1663 0.0365

ASP 1663 CYS 1664 0.0219

CYS 1664 ASP 1665 0.0411

ASP 1665 SER 1666 0.0147

SER 1666 ASP 1667 0.0423

ASP 1667 GLU 1668 0.0194

GLU 1668 PHE 1669 0.0367

PHE 1669 TYR 1670 0.0004

TYR 1670 SER 1671 0.0366

SER 1671 PHE 1672 0.0024

PHE 1672 SER 1673 0.0202

SER 1673 VAL 1674 0.0088

VAL 1674 MET 1675 0.0285

MET 1675 MET 1676 0.0029

MET 1676 ALA 1677 -0.0794

ALA 1677 THR 1678 0.0067

THR 1678 ALA 1679 0.0196

ALA 1679 SER 1680 0.0174

SER 1680 SER 1681 0.0019

SER 1681 THR 1682 0.0157

THR 1682 ILE 1683 0.0065

ILE 1683 ALA 1684 0.0115

ALA 1684 SER 1685 0.0155

SER 1685 SER 1686 0.0017

SER 1686 SER 1687 0.0106

SER 1687 MET 1688 0.0134

MET 1688 ALA 1689 0.0117

ALA 1689 PHE 1690 0.0197

PHE 1690 ALA 1691 0.0120

ALA 1691 ILE 1692 0.0195

ILE 1692 VAL 1693 -0.0407

VAL 1693 TYR 1694 0.0239

TYR 1694 GLY 1695 0.0110

GLY 1695 GLU 1696 0.0146

GLU 1696 VAL 1697 0.0130

VAL 1697 PRO 1698 0.0186

PRO 1698 LEU 1699 0.0001

LEU 1699 PRO 1700 0.0196

PRO 1700 ASP 1701 0.0247

ASP 1701 GLN 1702 0.0014

GLN 1702 PHE 1703 0.0254

PHE 1703 LEU 1704 0.0195

LEU 1704 ASP 1705 0.0167

ASP 1705 ASP 1706 0.0088

ASP 1706 MET 1707 0.0219

MET 1707 LYS 1708 0.0246

LYS 1708 THR 1709 -0.0135

THR 1709 ALA 1710 0.0233

ALA 1710 ILE 1711 0.0186

ILE 1711 SER 1712 0.0258

SER 1712 SER 1713 0.0011

SER 1713 SER 1714 0.0266

SER 1714 ALA 1715 0.0144

ALA 1715 VAL 1716 0.0260

VAL 1716 SER 1717 0.0049

SER 1717 ASP 1718 0.0231

ASP 1718 PRO 1719 0.0159

PRO 1719 VAL 1720 0.0015

VAL 1720 VAL 1721 0.0237

VAL 1721 GLY 1722 0.0025

GLY 1722 HIS 1723 0.0149

HIS 1723 LEU 1724 0.0251

LEU 1724 ASP 1725 -0.0422

ASP 1725 SER 1726 0.0224

SER 1726 ILE 1727 0.0066

ILE 1727 ASP 1728 0.0231

ASP 1728 ALA 1729 0.0136

ALA 1729 THR 1730 0.0230

THR 1730 GLY 1731 0.0059

GLY 1731 LYS 1732 0.0169

LYS 1732 PHE 1733 0.0141

PHE 1733 CYS 1734 0.0200

CYS 1734 ILE 1735 0.0194

ILE 1735 PHE 1736 0.0115

PHE 1736 ILE 1737 0.0220

ILE 1737 GLU 1738 0.0137

GLU 1738 ASP 1739 0.0233

ASP 1739 PRO 1740 0.0204

PRO 1740 GLU 1741 0.0078

GLU 1741 THR 1742 0.0150

THR 1742 ASP 1743 0.0247

ASP 1743 ILE 1744 0.0167

ILE 1744 LEU 1745 0.0248

LEU 1745 SER 1746 0.0240

SER 1746 SER 1747 0.0026

SER 1747 PRO 1748 0.0242

PRO 1748 ASP 1749 0.0066

ASP 1749 GLU 1750 0.0195

GLU 1750 LYS 1751 0.0221

LYS 1751 SER 1752 0.0021

SER 1752 TYR 1753 0.0247

TYR 1753 ALA 1754 0.0218

ALA 1754 SER 1755 0.0144

SER 1755 ILE 1756 0.0111

ILE 1756 GLN 1757 0.0385

GLN 1757 LYS 1758 0.0226

LYS 1758 LEU 1759 0.0033

LEU 1759 VAL 1760 0.0187

VAL 1760 THR 1761 0.0165

THR 1761 ARG 1762 0.0221

ARG 1762 CYS 1763 0.0030

CYS 1763 LYS 1764 0.0091

LYS 1764 GLY 1765 0.0176

GLY 1765 LEU 1766 0.0226

LEU 1766 ILE 1767 0.0148

ILE 1767 TRP 1768 0.0158

TRP 1768 VAL 1769 0.0184

VAL 1769 SER 1770 0.0223

SER 1770 ARG 1771 0.0195

ARG 1771 GLY 1772 0.0218

GLY 1772 GLY 1773 0.0214

GLY 1773 ALA 1774 0.0049

ALA 1774 MET 1775 0.0084

MET 1775 HIS 1776 0.0169

HIS 1776 GLY 1777 0.0014

GLY 1777 THR 1778 0.0187

THR 1778 ARG 1779 0.0065

ARG 1779 PRO 1780 0.0181

PRO 1780 ASN 1781 0.0100

ASN 1781 SER 1782 0.0101

SER 1782 SER 1783 0.0172

SER 1783 LEU 1784 0.0063

LEU 1784 LYS 1785 0.0171

LYS 1785 THR 1786 0.0049

THR 1786 GLY 1787 0.0151

GLY 1787 LEU 1788 0.0134

LEU 1788 LEU 1789 -0.0164

LEU 1789 ARG 1790 0.0186

ARG 1790 THR 1791 0.0068

THR 1791 LEU 1792 0.0225

LEU 1792 ARG 1793 0.0040

ARG 1793 LEU 1794 0.0205

LEU 1794 GLU 1795 0.0055

GLU 1795 TYR 1796 0.0193

TYR 1796 THR 1797 0.0041

THR 1797 GLU 1798 0.0230

GLU 1798 LYS 1799 0.0226

LYS 1799 ARG 1800 0.0116

ARG 1800 PHE 1801 0.0200

PHE 1801 ILE 1802 0.0134

ILE 1802 SER 1803 0.0228

SER 1803 LEU 1804 0.0162

LEU 1804 ASP 1805 0.0068

ASP 1805 LEU 1806 0.0191

LEU 1806 ASP 1807 0.0188

ASP 1807 SER 1808 0.0125

SER 1808 ALA 1809 0.0123

ALA 1809 ARG 1810 0.0223

ARG 1810 PRO 1811 0.0166

PRO 1811 GLN 1812 0.0094

GLN 1812 TRP 1813 0.0219

TRP 1813 ASN 1814 0.0003

ASN 1814 HIS 1815 0.0135

HIS 1815 ASP 1816 0.0202

ASP 1816 SER 1817 0.0051

SER 1817 ILE 1818 0.0230

ILE 1818 THR 1819 0.0035

THR 1819 THR 1820 0.0217

THR 1820 ILE 1821 0.0173

ILE 1821 ASN 1822 0.0159

ASN 1822 GLU 1823 0.0118

GLU 1823 VAL 1824 0.0094

VAL 1824 LEU 1825 0.0164

LEU 1825 CYS 1826 0.0064

CYS 1826 GLY 1827 0.0205

GLY 1827 ALA 1828 0.0021

ALA 1828 LEU 1829 0.0199

LEU 1829 ALA 1830 0.0029

ALA 1830 GLN 1831 0.0196

GLN 1831 ASN 1832 0.0206

ASN 1832 ALA 1833 0.0165

ALA 1833 ASP 1834 0.0124

ASP 1834 SER 1835 0.0202

SER 1835 SER 1836 0.0133

SER 1836 ILE 1837 0.0523

ILE 1837 LYS 1838 0.0144

LYS 1838 ASP 1839 0.0195

ASP 1839 SER 1840 0.0023

SER 1840 GLU 1841 0.0199

GLU 1841 PHE 1842 0.0140

PHE 1842 ALA 1843 0.0197

ALA 1843 GLU 1844 0.0157

GLU 1844 GLN 1845 0.0144

GLN 1845 ASP 1846 0.0133

ASP 1846 GLY 1847 0.0200

GLY 1847 GLN 1848 0.0175

GLN 1848 LEU 1849 0.0142

LEU 1849 PHE 1850 0.0197

PHE 1850 VAL 1851 0.0180

VAL 1851 PRO 1852 0.0177

PRO 1852 ARG 1853 0.1316

ARG 1853 ILE 1854 0.0209

ILE 1854 SER 1855 0.0210

SER 1855 CYS 1856 0.0247

CYS 1856 ASP 1857 0.0184

ASP 1857 ILE 1858 0.0168

ILE 1858 ALA 1859 0.0200

ALA 1859 ARG 1860 0.0060

ARG 1860 ASN 1861 0.0219

ASN 1861 GLU 1862 0.0215

GLU 1862 ASP 1863 0.0054

ASP 1863 LEU 1864 0.0205

LEU 1864 SER 1865 0.0136

SER 1865 SER 1866 0.0260

SER 1866 ASP 1867 0.0160

ASP 1867 SER 1868 0.0117

SER 1868 ASN 1869 -0.2345

ASN 1869 SER 1870 0.0000

SER 1870 PRO 1871 0.0171

PRO 1871 ALA 1872 0.0115

ALA 1872 GLN 1873 0.0029

GLN 1873 MET 1874 0.0117

MET 1874 GLU 1875 0.0089

GLU 1875 PRO 1876 0.0098

PRO 1876 PHE 1877 0.0156

PHE 1877 HIS 1878 0.0042

HIS 1878 GLN 1879 0.0173

GLN 1879 PRO 1880 0.0102

PRO 1880 GLY 1881 0.0144

GLY 1881 LYS 1882 0.0032

LYS 1882 LEU 1883 0.0088

LEU 1883 LEU 1884 0.0112

LEU 1884 GLN 1885 0.0007

GLN 1885 MET 1886 0.0155

MET 1886 GLY 1887 0.0007

GLY 1887 ILE 1888 0.0084

ILE 1888 LYS 1889 0.0094

LYS 1889 THR 1890 0.0110

THR 1890 PRO 1891 0.0193

PRO 1891 GLY 1892 0.0190

GLY 1892 LEU 1893 0.0163

LEU 1893 ILE 1894 0.0008

ILE 1894 ASP 1895 0.0193

ASP 1895 THR 1896 0.0186

THR 1896 LEU 1897 0.0048

LEU 1897 GLN 1898 0.0173

GLN 1898 PHE 1899 0.0122

PHE 1899 SER 1900 0.0180

SER 1900 LYS 1901 -0.0235

LYS 1901 THR 1902 0.0148

THR 1902 ASP 1903 0.0146

ASP 1903 ALA 1904 0.0051

ALA 1904 THR 1905 0.0149

THR 1905 ASP 1906 0.0031

ASP 1906 ASN 1907 0.0145

ASN 1907 LEU 1908 0.0149

LEU 1908 PRO 1909 0.0116

PRO 1909 ASN 1910 0.0107

ASN 1910 ASP 1911 0.0151

ASP 1911 TYR 1912 0.0154

TYR 1912 ILE 1913 0.0066

ILE 1913 GLU 1914 0.0155

GLU 1914 ILE 1915 0.0139

ILE 1915 GLU 1916 0.0142

GLU 1916 PRO 1917 0.0114

PRO 1917 LYS 1918 0.0082

LYS 1918 ALA 1919 0.0097

ALA 1919 PHE 1920 0.0029

PHE 1920 GLY 1921 0.0116

GLY 1921 LEU 1922 0.0039

LEU 1922 ASN 1923 0.0079

ASN 1923 PHE 1924 0.0050

PHE 1924 ARG 1925 0.0097

ARG 1925 ASP 1926 0.0128

ASP 1926 VAL 1927 0.0111

VAL 1927 MET 1928 0.0051

MET 1928 VAL 1929 0.0132

VAL 1929 ALA 1930 0.0131

ALA 1930 MET 1931 0.0070

MET 1931 GLY 1932 0.0086

GLY 1932 GLN 1933 0.0270

GLN 1933 LEU 1934 0.0134

LEU 1934 GLU 1935 0.0107

GLU 1935 GLU 1936 0.0051

GLU 1936 SER 1937 0.0128

SER 1937 ILE 1938 0.0015

ILE 1938 MET 1939 0.0058

MET 1939 GLY 1940 0.0001

GLY 1940 PHE 1941 0.0132

PHE 1941 GLU 1942 0.0002

GLU 1942 CYS 1943 0.0051

CYS 1943 ALA 1944 0.0000

ALA 1944 GLY 1945 0.0120

GLY 1945 VAL 1946 0.0105

VAL 1946 VAL 1947 0.0132

VAL 1947 ARG 1948 0.0141

ARG 1948 ARG 1949 0.0259

ARG 1949 VAL 1950 0.0136

VAL 1950 GLY 1951 0.0075

GLY 1951 PRO 1952 0.0128

PRO 1952 SER 1953 0.0124

SER 1953 SER 1954 0.0131

SER 1954 ALA 1955 0.0012

ALA 1955 GLY 1956 0.0143

GLY 1956 HIS 1957 0.0141

HIS 1957 ASN 1958 0.0034

ASN 1958 ILE 1959 0.0131

ILE 1959 LYS 1960 0.0097

LYS 1960 VAL 1961 0.0145

VAL 1961 GLY 1962 0.0109

GLY 1962 ASP 1963 0.0134

ASP 1963 ARG 1964 0.0139

ARG 1964 VAL 1965 0.0115

VAL 1965 CYS 1966 0.0058

CYS 1966 ALA 1967 0.0023

ALA 1967 LEU 1968 0.0014

LEU 1968 LEU 1969 0.0097

LEU 1969 GLY 1970 0.0024

GLY 1970 GLY 1971 0.0143

GLY 1971 GLN 1972 0.0126

GLN 1972 TRP 1973 0.0108

TRP 1973 THR 1974 0.0112

THR 1974 ASN 1975 0.0031

ASN 1975 THR 1976 0.0148

THR 1976 VAL 1977 0.0126

VAL 1977 ARG 1978 0.0140

ARG 1978 VAL 1979 0.0148

VAL 1979 HIS 1980 0.0148

HIS 1980 TRP 1981 0.0044

TRP 1981 HIS 1982 0.0121

HIS 1982 SER 1983 0.0138

SER 1983 VAL 1984 0.0007

VAL 1984 ALA 1985 0.0050

ALA 1985 PRO 1986 0.0009

PRO 1986 ILE 1987 0.0121

ILE 1987 PRO 1988 0.0027

PRO 1988 GLN 1989 0.0073

GLN 1989 ALA 1990 0.0133

ALA 1990 MET 1991 0.0015

MET 1991 ASP 1992 0.0130

ASP 1992 TRP 1993 0.0042

TRP 1993 GLU 1994 0.0112

GLU 1994 THR 1995 0.0137

THR 1995 ALA 1996 0.0134

ALA 1996 ALA 1997 0.0306

ALA 1997 SER 1998 0.0104

SER 1998 ILE 1999 0.0105

ILE 1999 PRO 2000 0.0045

PRO 2000 ILE 2001 0.0034

ILE 2001 VAL 2002 0.0089

VAL 2002 PHE 2003 0.0080

PHE 2003 VAL 2004 0.0052

VAL 2004 THR 2005 0.0054

THR 2005 ALA 2006 0.0068

ALA 2006 TYR 2007 0.0096

TYR 2007 ILE 2008 0.0013

ILE 2008 SER 2009 0.0091

SER 2009 LEU 2010 0.0055

LEU 2010 VAL 2011 0.0085

VAL 2011 LYS 2012 0.0050

LYS 2012 ILE 2013 -0.0238

ILE 2013 ALA 2014 0.0063

ALA 2014 ARG 2015 0.0024

ARG 2015 MET 2016 0.0056

MET 2016 GLN 2017 0.0031

GLN 2017 ALA 2018 0.0024

ALA 2018 GLY 2019 0.0063

GLY 2019 GLU 2020 0.0006

GLU 2020 THR 2021 0.0056

THR 2021 VAL 2022 0.0055

VAL 2022 LEU 2023 0.0046

LEU 2023 ILE 2024 0.0067

ILE 2024 HIS 2025 0.0038

HIS 2025 ALA 2026 0.0064

ALA 2026 ALA 2027 0.0005

ALA 2027 SER 2028 0.0057

SER 2028 GLY 2029 -0.0123

GLY 2029 GLY 2030 0.0067

GLY 2030 VAL 2031 0.0050

VAL 2031 GLY 2032 0.0074

GLY 2032 GLN 2033 0.0000

GLN 2033 ALA 2034 0.0074

ALA 2034 ALA 2035 0.0050

ALA 2035 ILE 2036 0.0044

ILE 2036 ILE 2037 0.0031

ILE 2037 LEU 2038 0.0060

LEU 2038 ALA 2039 0.0069

ALA 2039 LYS 2040 0.0010

LYS 2040 HIS 2041 0.0067

HIS 2041 VAL 2042 0.0040

VAL 2042 GLY 2043 0.0069

GLY 2043 ALA 2044 0.0019

ALA 2044 GLU 2045 0.0375

GLU 2045 ILE 2046 0.0058

ILE 2046 PHE 2047 0.0029

PHE 2047 ALA 2048 0.0069

ALA 2048 THR 2049 0.0033

THR 2049 VAL 2050 0.0076

VAL 2050 GLY 2051 0.0046

GLY 2051 THR 2052 0.0048

THR 2052 ASP 2053 0.0027

ASP 2053 GLU 2054 0.0047

GLU 2054 LYS 2055 0.0072

LYS 2055 ARG 2056 0.0071

ARG 2056 ASP 2057 0.0015

ASP 2057 LEU 2058 0.0069

LEU 2058 LEU 2059 0.0074

LEU 2059 ILE 2060 0.0054

ILE 2060 LYS 2061 0.0030

LYS 2061 GLU 2062 0.0057

GLU 2062 TYR 2063 0.0053

TYR 2063 LYS 2064 0.0056

LYS 2064 ILE 2065 0.0010

ILE 2065 PRO 2066 0.0054

PRO 2066 ASP 2067 0.0034

ASP 2067 ASP 2068 0.0040

ASP 2068 HIS 2069 0.0058

HIS 2069 ILE 2070 0.0049

ILE 2070 PHE 2071 0.0003

PHE 2071 SER 2072 0.0029

SER 2072 SER 2073 0.0052

SER 2073 ARG 2074 0.0021

ARG 2074 ASN 2075 0.0050

ASN 2075 ALA 2076 0.0056

ALA 2076 LEU 2077 -0.0177

LEU 2077 PHE 2078 0.0015

PHE 2078 ALA 2079 0.0035

ALA 2079 LYS 2080 0.0040

LYS 2080 SER 2081 0.0011

SER 2081 ILE 2082 0.0034

ILE 2082 ARG 2083 0.0036

ARG 2083 GLN 2084 0.0033

GLN 2084 ARG 2085 0.0011

ARG 2085 THR 2086 0.0040

THR 2086 ASN 2087 0.0040

ASN 2087 GLY 2088 0.0006

GLY 2088 LYS 2089 0.0038

LYS 2089 GLY 2090 0.0035

GLY 2090 VAL 2091 0.0036

VAL 2091 ASP 2092 0.0036

ASP 2092 VAL 2093 0.0410

VAL 2093 VAL 2094 0.0020

VAL 2094 LEU 2095 0.0029

LEU 2095 ASN 2096 0.0009

ASN 2096 CYS 2097 0.0024

CYS 2097 LEU 2098 0.0022

LEU 2098 ALA 2099 -0.0000

ALA 2099 GLY 2100 0.0013

GLY 2100 GLY 2101 0.0028

GLY 2101 LEU 2102 -0.0000

LEU 2102 LEU 2103 0.0031

LEU 2103 GLN 2104 0.0025

GLN 2104 GLU 2105 0.0018

GLU 2105 SER 2106 0.0013

SER 2106 PHE 2107 0.0024

PHE 2107 ASP 2108 0.0029

ASP 2108 CYS 2109 0.0147

CYS 2109 LEU 2110 0.0046

LEU 2110 ALA 2111 0.0036

ALA 2111 ASP 2112 0.0039

ASP 2112 PHE 2113 0.0042

PHE 2113 GLY 2114 0.0047

GLY 2114 ARG 2115 0.0034

ARG 2115 PHE 2116 0.0040

PHE 2116 ILE 2117 0.0045

ILE 2117 GLU 2118 0.0029

GLU 2118 ILE 2119 0.0047

ILE 2119 GLY 2120 0.0039

GLY 2120 LYS 2121 0.0002

LYS 2121 ARG 2122 0.0047

ARG 2122 ASP 2123 0.0047

ASP 2123 ILE 2124 0.0037

ILE 2124 GLU 2125 0.0144

GLU 2125 LEU 2126 0.0031

LEU 2126 ASN 2127 0.0033

ASN 2127 HIS 2128 0.0015

HIS 2128 CYS 2129 0.0030

CYS 2129 LEU 2130 0.0014

LEU 2130 ASN 2131 0.0028

ASN 2131 MET 2132 0.0028

MET 2132 GLY 2133 0.0013

GLY 2133 MET 2134 0.0022

MET 2134 PHE 2135 0.0020

PHE 2135 ALA 2136 0.0029

ALA 2136 ARG 2137 0.0008

ARG 2137 SER 2138 0.0023

SER 2138 ALA 2139 0.0031

ALA 2139 THR 2140 0.0022

THR 2140 PHE 2141 -0.0353

PHE 2141 THR 2142 0.0075

THR 2142 ALA 2143 0.0071

ALA 2143 VAL 2144 0.0053

VAL 2144 ASP 2145 0.0070

ASP 2145 LEU 2146 0.0052

LEU 2146 ILE 2147 0.0038

ILE 2147 ALA 2148 0.0037

ALA 2148 ILE 2149 0.0041

ILE 2149 GLY 2150 0.0071

GLY 2150 ARG 2151 0.0003

ARG 2151 ASP 2152 0.0066

ASP 2152 ARG 2153 0.0026

ARG 2153 SER 2154 0.0042

SER 2154 TYR 2155 0.0062

TYR 2155 MET 2156 0.0059

MET 2156 PHE 2157 -0.0009

PHE 2157 ALA 2158 0.0077

ALA 2158 GLU 2159 0.0113

GLU 2159 ALA 2160 0.0117

ALA 2160 LEU 2161 0.0092

LEU 2161 PRO 2162 0.0045

PRO 2162 LYS 2163 0.0115

LYS 2163 ILE 2164 0.0117

ILE 2164 MET 2165 0.0063

MET 2165 THR 2166 0.0081

THR 2166 LEU 2167 0.0116

LEU 2167 LEU 2168 0.0110

LEU 2168 GLN 2169 0.0050

GLN 2169 GLU 2170 0.0104

GLU 2170 LYS 2171 0.0116

LYS 2171 ALA 2172 0.0077

ALA 2172 ILE 2173 -0.0115

ILE 2173 ARG 2174 0.0133

ARG 2174 PRO 2175 0.0091

PRO 2175 VAL 2176 0.0071

VAL 2176 THR 2177 0.0126

THR 2177 PRO 2178 0.0130

PRO 2178 ILE 2179 0.0132

ILE 2179 SER 2180 0.0111

SER 2180 ILE 2181 0.0130

ILE 2181 TYR 2182 0.0088

TYR 2182 LYS 2183 0.0135

LYS 2183 ILE 2184 0.0054

ILE 2184 GLY 2185 0.0129

GLY 2185 ASP 2186 0.0134

ASP 2186 ILE 2187 0.0086

ILE 2187 GLU 2188 0.0059

GLU 2188 THR 2189 -0.0545

THR 2189 ALA 2190 0.0110

ALA 2190 PHE 2191 0.0005

PHE 2191 ARG 2192 0.0112

ARG 2192 LEU 2193 0.0053

LEU 2193 MET 2194 0.0101

MET 2194 GLN 2195 0.0017

GLN 2195 ALA 2196 0.0104

ALA 2196 GLY 2197 0.0099

GLY 2197 LYS 2198 0.0031

LYS 2198 HIS 2199 0.0071

HIS 2199 MET 2200 0.0077

MET 2200 GLY 2201 0.0105

GLY 2201 LYS 2202 0.0111

LYS 2202 ILE 2203 0.0113

ILE 2203 VAL 2204 0.0095

VAL 2204 ILE 2205 -0.0886

ILE 2205 THR 2206 0.0010

THR 2206 ALA 2207 0.0114

ALA 2207 PRO 2208 0.0029

PRO 2208 GLU 2209 0.0095

GLU 2209 ASP 2210 0.0117

ASP 2210 ALA 2211 0.0006

ALA 2211 MET 2212 0.0081

MET 2212 VAL 2213 0.0018

VAL 2213 PRO 2214 0.0052

PRO 2214 VAL 2215 0.0122

VAL 2215 ILE 2216 0.0072

ILE 2216 THR 2217 0.0106

THR 2217 ARG 2218 0.0071

ARG 2218 PRO 2219 0.0124

PRO 2219 PRO 2220 0.0110

PRO 2220 LYS 2221 -0.0008

LYS 2221 LEU 2222 0.0070

LEU 2222 GLN 2223 0.0048

GLN 2223 LEU 2224 0.0058

LEU 2224 ARG 2225 0.0053

ARG 2225 PRO 2226 0.0065

PRO 2226 ASP 2227 0.0092

ASP 2227 ALA 2228 0.0140

ALA 2228 SER 2229 0.0151

SER 2229 TYR 2230 0.0057

TYR 2230 LEU 2231 0.0151

LEU 2231 ILE 2232 0.0115

ILE 2232 VAL 2233 0.0153

VAL 2233 GLY 2234 0.0150

GLY 2234 GLY 2235 0.0147

GLY 2235 LEU 2236 0.0142

LEU 2236 GLY 2237 0.0470

GLY 2237 GLY 2238 0.0073

GLY 2238 ILE 2239 0.0151

ILE 2239 GLY 2240 0.0011

GLY 2240 ARG 2241 0.0154

ARG 2241 SER 2242 0.0073

SER 2242 LEU 2243 0.0141

LEU 2243 CYS 2244 0.0023

CYS 2244 LYS 2245 0.0142

LYS 2245 ASN 2246 0.0113

ASN 2246 PHE 2247 0.0069

PHE 2247 VAL 2248 0.0096

VAL 2248 GLU 2249 0.0087

GLU 2249 ASN 2250 0.0154

ASN 2250 GLY 2251 0.0008

GLY 2251 ALA 2252 0.0133

ALA 2252 ARG 2253 0.0280

ARG 2253 SER 2254 0.0130

SER 2254 LEU 2255 0.0111

LEU 2255 VAL 2256 0.0136

VAL 2256 LEU 2257 0.0120

LEU 2257 LEU 2258 0.0144

LEU 2258 SER 2259 0.0140

SER 2259 ARG 2260 0.0132

ARG 2260 ASN 2261 0.0124

ASN 2261 ALA 2262 0.0119

ALA 2262 ASN 2263 0.0090

ASN 2263 VAL 2264 0.0072

VAL 2264 SER 2265 0.0123

SER 2265 GLN 2266 0.0142

GLN 2266 GLN 2267 0.0001

GLN 2267 SER 2268 0.0145

SER 2268 GLY 2269 0.0379

GLY 2269 GLU 2270 0.0099

GLU 2270 PHE 2271 0.0124

PHE 2271 LEU 2272 0.0023

LEU 2272 ASP 2273 0.0117

ASP 2273 GLU 2274 0.0060

GLU 2274 LEU 2275 0.0131

LEU 2275 ARG 2276 0.0007

ARG 2276 SER 2277 0.0134

SER 2277 THR 2278 0.0125

THR 2278 GLY 2279 0.0025

GLY 2279 CYS 2280 0.0125

CYS 2280 ILE 2281 0.0084

ILE 2281 VAL 2282 0.0099

VAL 2282 GLY 2283 0.0118

GLY 2283 VAL 2284 0.0103

VAL 2284 VAL 2285 -0.1277

VAL 2285 ASP 2286 0.0157

ASP 2286 CYS 2287 0.0126

CYS 2287 ASP 2288 0.0103

ASP 2288 ILE 2289 0.0115

ILE 2289 SER 2290 0.0150

SER 2290 SER 2291 0.0013

SER 2291 LYS 2292 0.0152

LYS 2292 THR 2293 0.0006

THR 2293 GLN 2294 0.0155

GLN 2294 VAL 2295 0.0096

VAL 2295 GLU 2296 0.0093

GLU 2296 ALA 2297 0.0069

ALA 2297 THR 2298 0.0106

THR 2298 MET 2299 0.0142

MET 2299 LEU 2300 0.0014

LEU 2300 ARG 2301 -0.0156

ARG 2301 LEU 2302 0.0056

LEU 2302 LYS 2303 0.0142

LYS 2303 LYS 2304 0.0037

LYS 2304 ASP 2305 0.0139

ASP 2305 MET 2306 0.0025

MET 2306 LEU 2307 0.0111

LEU 2307 PRO 2308 0.0122

PRO 2308 ILE 2309 0.0066

ILE 2309 ARG 2310 0.0038

ARG 2310 GLY 2311 0.0078

GLY 2311 ILE 2312 0.0147

ILE 2312 VAL 2313 0.0088

VAL 2313 HIS 2314 0.0149

HIS 2314 ALA 2315 0.0129

ALA 2315 GLY 2316 0.0108

GLY 2316 MET 2317 -0.0333

MET 2317 VAL 2318 0.0111

VAL 2318 LEU 2319 0.0164

LEU 2319 GLN 2320 0.0135

GLN 2320 ASP 2321 0.0114

ASP 2321 SER 2322 0.0174

SER 2322 VAL 2323 0.0116

VAL 2323 PHE 2324 0.0180

PHE 2324 GLU 2325 0.0141

GLU 2325 ARG 2326 0.0075

ARG 2326 MET 2327 0.0178

MET 2327 SER 2328 0.0049

SER 2328 LEU 2329 0.0179

LEU 2329 ASP 2330 0.0137

ASP 2330 ASP 2331 0.0096

ASP 2331 TYR 2332 0.0090

TYR 2332 ASN 2333 -0.0667

ASN 2333 THR 2334 0.0108

THR 2334 ALA 2335 0.0015

ALA 2335 ILE 2336 0.0108

ILE 2336 ARG 2337 0.0038

ARG 2337 PRO 2338 0.0111

PRO 2338 LYS 2339 0.0011

LYS 2339 VAL 2340 0.0113

VAL 2340 GLN 2341 0.0018

GLN 2341 GLY 2342 0.0114

GLY 2342 SER 2343 0.0032

SER 2343 TRP 2344 0.0111

TRP 2344 ASN 2345 0.0017

ASN 2345 LEU 2346 0.0097

LEU 2346 HIS 2347 0.0065

HIS 2347 SER 2348 0.0053

SER 2348 GLY 2349 -0.0266

GLY 2349 LEU 2350 0.0105

LEU 2350 SER 2351 0.0158

SER 2351 ASP 2352 0.0117

ASP 2352 CYS 2353 0.0121

CYS 2353 ASP 2354 0.0062

ASP 2354 LEU 2355 0.0113

LEU 2355 ASP 2356 0.0057

ASP 2356 PHE 2357 0.0151

PHE 2357 PHE 2358 0.0153

PHE 2358 ILE 2359 0.0124

ILE 2359 MET 2360 0.0162

MET 2360 LEU 2361 0.0140

LEU 2361 SER 2362 0.0144

SER 2362 SER 2363 0.0107

SER 2363 LEU 2364 0.0010

LEU 2364 ALA 2365 0.0489

ALA 2365 GLY 2366 0.0182

GLY 2366 VAL 2367 0.0000

VAL 2367 SER 2368 0.0177

SER 2368 GLY 2369 0.0063

GLY 2369 SER 2370 0.0119

SER 2370 ALA 2371 0.0151

ALA 2371 SER 2372 0.0001

SER 2372 GLN 2373 0.0182

GLN 2373 ALA 2374 0.0183

ALA 2374 ASN 2375 0.0093

ASN 2375 TYR 2376 0.0155

TYR 2376 THR 2377 0.0023

THR 2377 ALA 2378 0.0164

ALA 2378 GLY 2379 0.0149

GLY 2379 GLY 2380 0.0050

GLY 2380 ALA 2381 0.0137

ALA 2381 TYR 2382 0.0077

TYR 2382 GLN 2383 0.0160

GLN 2383 ASP 2384 0.0004

ASP 2384 ALA 2385 0.0158

ALA 2385 LEU 2386 0.0077

LEU 2386 ALA 2387 0.0101

ALA 2387 LYS 2388 0.0086

LYS 2388 TYR 2389 0.0079

TYR 2389 ARG 2390 0.0144

ARG 2390 ARG 2391 0.0022

ARG 2391 ALA 2392 0.0155

ALA 2392 GLN 2393 0.0055

GLN 2393 GLY 2394 0.0139

GLY 2394 LEU 2395 0.0092

LEU 2395 SER 2396 0.0155

SER 2396 ALA 2397 0.0691

ALA 2397 VAL 2398 0.0066

VAL 2398 SER 2399 0.0154

SER 2399 ILE 2400 0.0108

ILE 2400 ASP 2401 0.0138

ASP 2401 LEU 2402 0.0156

LEU 2402 GLY 2403 0.0086

GLY 2403 MET 2404 0.0155

MET 2404 VAL 2405 0.0142

VAL 2405 GLN 2406 0.0136

GLN 2406 SER 2407 0.0113

SER 2407 VAL 2408 0.0025

VAL 2408 GLY 2409 0.0100

GLY 2409 TYR 2410 0.0156

TYR 2410 VAL 2411 0.0008

VAL 2411 ALA 2412 0.0158

ALA 2412 GLU 2413 -0.0450

GLU 2413 THR 2414 0.0187

THR 2414 LYS 2415 0.0123

LYS 2415 GLY 2416 0.0092

GLY 2416 VAL 2417 0.0188

VAL 2417 ALA 2418 0.0076

ALA 2418 GLU 2419 0.0113

GLU 2419 ARG 2420 0.0175

ARG 2420 LEU 2421 0.0188

LEU 2421 VAL 2422 0.0034

VAL 2422 ARG 2423 0.0178

ARG 2423 MET 2424 0.0170

MET 2424 GLY 2425 0.0116

GLY 2425 TYR 2426 0.0119

TYR 2426 SER 2427 0.0166

SER 2427 PRO 2428 0.0131

PRO 2428 ILE 2429 0.0471

ILE 2429 SER 2430 0.0102

SER 2430 GLU 2431 0.0020

GLU 2431 MET 2432 0.0093

MET 2432 GLU 2433 0.0084

GLU 2433 VAL 2434 0.0036

VAL 2434 LEU 2435 0.0090

LEU 2435 LYS 2436 0.0046

LYS 2436 ILE 2437 0.0119

ILE 2437 VAL 2438 0.0004

VAL 2438 GLU 2439 0.0116

GLU 2439 HIS 2440 0.0053

HIS 2440 ALA 2441 0.0084

ALA 2441 ILE 2442 0.0060

ILE 2442 THR 2443 0.0075

THR 2443 ASN 2444 0.0064

ASN 2444 PRO 2445 -0.0519

PRO 2445 PRO 2446 0.0127

PRO 2446 PRO 2447 0.0149

PRO 2447 GLU 2448 0.0159

GLU 2448 ALA 2449 0.0058

ALA 2449 SER 2450 0.0114

SER 2450 SER 2451 0.0157

SER 2451 ALA 2452 0.0014

ALA 2452 GLN 2453 0.0163

GLN 2453 ILE 2454 0.0138

ILE 2454 ILE 2455 0.0160

ILE 2455 THR 2456 0.0164

THR 2456 GLY 2457 0.0162

GLY 2457 ILE 2458 0.0094

ILE 2458 SER 2459 0.0088

SER 2459 THR 2460 0.0014

THR 2460 LYS 2461 -0.0640

LYS 2461 PRO 2462 0.0129

PRO 2462 GLY 2463 0.0075

GLY 2463 ARG 2464 0.0108

ARG 2464 HIS 2465 0.0100

HIS 2465 TRP 2466 0.0080

TRP 2466 THR 2467 0.0151

THR 2467 GLU 2468 0.0009

GLU 2468 SER 2469 0.0129

SER 2469 SER 2470 0.0141

SER 2470 TRP 2471 0.0151

TRP 2471 LEU 2472 0.0021

LEU 2472 GLN 2473 0.0139

GLN 2473 ASP 2474 0.0139

ASP 2474 ALA 2475 0.0067

ALA 2475 ARG 2476 0.0140

ARG 2476 PHE 2477 0.0280

PHE 2477 ALA 2478 0.0051

ALA 2478 THR 2479 0.0093

THR 2479 LEU 2480 0.0113

LEU 2480 ARG 2481 0.0147

ARG 2481 GLU 2482 0.0000

GLU 2482 ARG 2483 0.0146

ARG 2483 ALA 2484 0.0097

ALA 2484 ARG 2485 0.0094

ARG 2485 ASP 2486 0.0049

ASP 2486 VAL 2487 0.0121

VAL 2487 LYS 2488 0.0144

LYS 2488 GLU 2489 0.0021

GLU 2489 LEU 2490 0.0123

LEU 2490 SER 2491 0.0118

SER 2491 ASN 2492 0.0112

ASN 2492 SER 2493 0.0401

SER 2493 GLN 2494 0.0089

GLN 2494 ASN 989 0.2351

ASN 989 LYS 990 0.0105

LYS 990 ALA 991 0.0139

ALA 991 HIS 992 0.0135

HIS 992 ARG 993 0.0074

ARG 993 GLN 994 0.0129

GLN 994 ARG 995 0.0140

ARG 995 VAL 996 0.0058

VAL 996 HIS 997 0.0134

HIS 997 PRO 998 0.0140

PRO 998 PRO 999 0.0106

PRO 999 HIS 1000 0.0120

HIS 1000 ASP 1001 0.0134

ASP 1001 LEU 1002 0.0106

LEU 1002 LEU 1003 0.0078

LEU 1003 GLY 1004 0.0137

GLY 1004 SER 1005 -0.0019

SER 1005 LEU 1006 0.0081

LEU 1006 ILE 1007 0.0005

ILE 1007 VAL 1008 0.0095

VAL 1008 GLY 1009 0.0042

GLY 1009 ARG 1010 0.0100

ARG 1010 ASP 1011 0.0097

ASP 1011 LEU 1012 0.0004

LEU 1012 ARG 1013 0.0093

ARG 1013 GLU 1014 0.0088

GLU 1014 PRO 1015 0.0066

PRO 1015 THR 1016 0.0097

THR 1016 TRP 1017 0.0060

TRP 1017 ARG 1018 0.0090

ARG 1018 HIS 1019 0.0062

HIS 1019 PHE 1020 0.0098

PHE 1020 ILE 1021 0.0211

ILE 1021 ARG 1022 0.0151

ARG 1022 VAL 1023 0.0095

VAL 1023 GLN 1024 0.0132

GLN 1024 ASP 1025 0.0179

ASP 1025 ILE 1026 0.0175

ILE 1026 PRO 1027 0.0140

PRO 1027 TRP 1028 0.0171

TRP 1028 ILE 1029 0.0013

ILE 1029 ARG 1030 0.0174

ARG 1030 ASP 1031 0.0129

ASP 1031 HIS 1032 0.0072

HIS 1032 VAL 1033 0.0116

VAL 1033 VAL 1034 0.0097

VAL 1034 GLN 1035 0.0133

GLN 1035 SER 1036 0.0160

SER 1036 ALA 1037 -0.0070

ALA 1037 LEU 1038 0.0086

LEU 1038 VAL 1039 0.0115

VAL 1039 TYR 1040 0.0113

TYR 1040 PRO 1041 0.0098

PRO 1041 GLY 1042 0.0087

GLY 1042 ALA 1043 0.0042

ALA 1043 GLY 1044 0.0119

GLY 1044 PHE 1045 0.0032

PHE 1045 ILE 1046 0.0095

ILE 1046 CYS 1047 0.0057

CYS 1047 MET 1048 0.0064

MET 1048 ALA 1049 0.0104

ALA 1049 MET 1050 0.0027

MET 1050 GLU 1051 0.0117

GLU 1051 ALA 1052 0.0023

ALA 1052 MET 1053 0.0122

MET 1053 VAL 1054 0.0030

VAL 1054 GLN 1055 0.0121

GLN 1055 LEU 1056 0.0074

LEU 1056 HIS 1057 0.0068

HIS 1057 GLU 1058 0.0103

GLU 1058 LEU 1059 0.0049

LEU 1059 ARG 1060 0.0134

ARG 1060 ASP 1061 0.0047

ASP 1061 SER 1062 0.0089

SER 1062 GLN 1063 0.0118

GLN 1063 SER 1064 0.0079

SER 1064 ARG 1065 0.0131

ARG 1065 LYS 1066 0.0095

LYS 1066 VAL 1067 0.0105

VAL 1067 ALA 1068 0.0134

ALA 1068 GLY 1069 0.0227

GLY 1069 TYR 1070 0.0033

TYR 1070 ARG 1071 0.0056

ARG 1071 LEU 1072 0.0056

LEU 1072 ALA 1073 0.0048

ALA 1073 GLU 1074 0.0050

GLU 1074 VAL 1075 0.0091

VAL 1075 ASP 1076 0.0068

ASP 1076 ILE 1077 0.0099

ILE 1077 LEU 1078 0.0018

LEU 1078 ARG 1079 0.0103

ARG 1079 ALA 1080 0.0037

ALA 1080 MET 1081 0.0106

MET 1081 LEU 1082 0.0105

LEU 1082 ILE 1083 0.0066

ILE 1083 PRO 1084 0.0102

PRO 1084 ASP 1085 -0.0014

ASP 1085 THR 1086 0.0077

THR 1086 SER 1087 0.0090

SER 1087 GLU 1088 0.0047

GLU 1088 GLY 1089 0.0089

GLY 1089 LEU 1090 0.0070

LEU 1090 GLU 1091 0.0089

GLU 1091 ALA 1092 0.0089

ALA 1092 HIS 1093 0.0092

HIS 1093 ILE 1094 0.0084

ILE 1094 SER 1095 0.0070

SER 1095 LEU 1096 0.0089

LEU 1096 ARG 1097 0.0053

ARG 1097 PRO 1098 0.0092

PRO 1098 CYS 1099 0.0089

CYS 1099 SER 1100 0.0045

SER 1100 THR 1101 -0.0153

THR 1101 LYS 1102 0.0037

LYS 1102 LEU 1103 0.0025

LEU 1103 LEU 1104 0.0056

LEU 1104 LEU 1105 0.0013

LEU 1105 THR 1106 0.0046

THR 1106 ASN 1107 0.0049

ASN 1107 GLU 1108 0.0060

GLU 1108 TRP 1109 0.0064

TRP 1109 TYR 1110 0.0060

TYR 1110 ASP 1111 0.0050

ASP 1111 PHE 1112 0.0048

PHE 1112 CYS 1113 0.0054

CYS 1113 VAL 1114 0.0045

VAL 1114 SER 1115 0.0047

SER 1115 SER 1116 0.0062

SER 1116 VAL 1117 0.0052

VAL 1117 GLY 1118 0.0075

GLY 1118 ASP 1119 0.0066

ASP 1119 ASP 1120 0.0012

ASP 1120 ASP 1121 0.0075

ASP 1121 LYS 1122 0.0079

LYS 1122 PHE 1123 0.0044

PHE 1123 VAL 1124 0.0059

VAL 1124 ASP 1125 0.0062

ASP 1125 HIS 1126 0.0011

HIS 1126 CYS 1127 0.0072

CYS 1127 ARG 1128 0.0069

ARG 1128 GLY 1129 0.0068

GLY 1129 ARG 1130 0.0075

ARG 1130 ILE 1131 0.0033

ILE 1131 THR 1132 0.0068

THR 1132 ILE 1133 0.0340

ILE 1133 GLU 1134 0.0132

GLU 1134 PHE 1135 0.0084

PHE 1135 ASP 1136 0.0084

ASP 1136 THR 1137 0.0107

THR 1137 SER 1138 0.0084

SER 1138 GLY 1139 0.0107

GLY 1139 SER 1140 0.0117

SER 1140 ALA 1141 0.0095

ALA 1141 ASP 1142 0.0140

ASP 1142 THR 1143 0.0032

THR 1143 PRO 1144 0.0098

PRO 1144 ARG 1145 0.0135

ARG 1145 THR 1146 0.0140

THR 1146 SER 1147 0.0042

SER 1147 LEU 1148 0.0135

LEU 1148 ARG 1149 -0.0078

ARG 1149 GLU 1150 0.0063

GLU 1150 ARG 1151 0.0205

ARG 1151 SER 1152 0.0034

SER 1152 ARG 1153 0.0212

ARG 1153 SER 1154 0.0207

SER 1154 THR 1155 0.0145

THR 1155 GLY 1156 0.0167

GLY 1156 LEU 1157 0.0037

LEU 1157 MET 1158 0.0201

MET 1158 ARG 1159 0.0150

ARG 1159 SER 1160 0.0138

SER 1160 VAL 1161 0.0214

VAL 1161 ASP 1162 0.0136

ASP 1162 PRO 1163 0.0154

PRO 1163 SER 1164 0.0147

SER 1164 ASN 1165 -0.0530

ASN 1165 LEU 1166 0.0094

LEU 1166 TYR 1167 0.0201

TYR 1167 SER 1168 0.0206

SER 1168 PHE 1169 0.0099

PHE 1169 LEU 1170 0.0137

LEU 1170 ARG 1171 0.0202

ARG 1171 ALA 1172 0.0186

ALA 1172 GLN 1173 0.0075

GLN 1173 GLY 1174 0.0197

GLY 1174 ILE 1175 0.0166

ILE 1175 TYR 1176 0.0097

TYR 1176 HIS 1177 0.0132

HIS 1177 GLY 1178 0.0127

GLY 1178 PRO 1179 0.0027

PRO 1179 ILE 1180 0.0187

ILE 1180 PHE 1181 0.0705

PHE 1181 GLN 1182 0.0090

GLN 1182 ASN 1183 0.0142

ASN 1183 LEU 1184 0.0154

LEU 1184 LYS 1185 0.0032

LYS 1185 THR 1186 0.0151

THR 1186 ILE 1187 0.0063

ILE 1187 SER 1188 0.0155

SER 1188 SER 1189 0.0041

SER 1189 ARG 1190 0.0115

ARG 1190 LYS 1191 0.0025

LYS 1191 ASP 1192 0.0119

ASP 1192 HIS 1193 0.0087

HIS 1193 SER 1194 0.0060

SER 1194 GLU 1195 0.0076

GLU 1195 SER 1196 0.0143

SER 1196 SER 1197 -0.0081

SER 1197 PHE 1198 0.0174

PHE 1198 VAL 1199 0.0137

VAL 1199 VAL 1200 0.0154

VAL 1200 ALA 1201 0.0175

ALA 1201 ASN 1202 0.0144

ASN 1202 THR 1203 0.0045

THR 1203 ALA 1204 0.0151

ALA 1204 SER 1205 0.0109

SER 1205 VAL 1206 0.0076

VAL 1206 MET 1207 0.0138

MET 1207 PRO 1208 0.0170

PRO 1208 ASN 1209 0.0056

ASN 1209 GLY 1210 0.0174

GLY 1210 PHE 1211 0.0095

PHE 1211 GLN 1212 0.0103

GLN 1212 SER 1213 0.0074

SER 1213 PRO 1214 0.0166

PRO 1214 HIS 1215 0.0125

HIS 1215 VAL 1216 0.0174

VAL 1216 ILE 1217 0.0175

ILE 1217 HIS 1218 0.0175

HIS 1218 PRO 1219 0.0097

PRO 1219 THR 1220 0.0082

THR 1220 THR 1221 0.0151

THR 1221 LEU 1222 0.0041

LEU 1222 ASP 1223 0.0166

ASP 1223 SER 1224 0.0045

SER 1224 ILE 1225 0.0155

ILE 1225 PHE 1226 0.0048

PHE 1226 GLN 1227 0.0126

GLN 1227 GLY 1228 0.0141

GLY 1228 ALA 1229 -0.0206

ALA 1229 TYR 1230 0.0123

TYR 1230 THR 1231 0.0031

THR 1231 ALA 1232 0.0097

ALA 1232 LEU 1233 0.0097

LEU 1233 PRO 1234 0.0113

PRO 1234 GLY 1235 0.0052

GLY 1235 ALA 1236 0.0127

ALA 1236 GLY 1237 0.0049

GLY 1237 LEU 1238 0.0104

LEU 1238 ASP 1239 0.0072

ASP 1239 GLN 1240 0.0046

GLN 1240 ASN 1241 0.0065

ASN 1241 THR 1242 0.0108

THR 1242 ALA 1243 0.0121

ALA 1243 MET 1244 0.0119

MET 1244 ILE 1245 -0.0177

ILE 1245 PRO 1246 0.0126

PRO 1246 ARG 1247 0.0008

ARG 1247 SER 1248 0.0129

SER 1248 ILE 1249 0.0086

ILE 1249 GLN 1250 0.0110

GLN 1250 GLU 1251 0.0065

GLU 1251 LEU 1252 0.0041

LEU 1252 TYR 1253 0.0074

TYR 1253 LEU 1254 0.0055

LEU 1254 SER 1255 0.0067

SER 1255 SER 1256 0.0110

SER 1256 ALA 1257 0.0027

ALA 1257 LEU 1258 0.0125

LEU 1258 THR 1259 0.0074

THR 1259 SER 1260 0.0123

SER 1260 ASP 1261 0.0047

ASP 1261 VAL 1262 0.0148

VAL 1262 GLY 1263 0.0135

GLY 1263 GLN 1264 0.0145

GLN 1264 CYS 1265 0.0151

CYS 1265 LEU 1266 0.0038

LEU 1266 VAL 1267 0.0148

VAL 1267 SER 1268 0.0016

SER 1268 ASP 1269 0.0136

ASP 1269 THR 1270 0.0045

THR 1270 SER 1271 0.0091

SER 1271 LEU 1272 0.0078

LEU 1272 ILE 1273 0.0034

ILE 1273 ARG 1274 0.0113

ARG 1274 TYR 1275 0.0154

TYR 1275 ASP 1276 0.0082

ASP 1276 GLY 1277 -0.0046

GLY 1277 GLN 1278 0.0090

GLN 1278 SER 1279 0.0127

SER 1279 PHE 1280 0.0074

PHE 1280 THR 1281 0.0130

THR 1281 VAL 1282 0.0035

VAL 1282 ASN 1283 0.0115

ASN 1283 VAL 1284 0.0044

VAL 1284 ASP 1285 0.0079

ASP 1285 VAL 1286 0.0065

VAL 1286 SER 1287 0.0044

SER 1287 SER 1288 0.0040

SER 1288 LYS 1289 0.0053

LYS 1289 ALA 1290 0.0087

ALA 1290 ASP 1291 0.0089

ASP 1291 SER 1292 0.0113

SER 1292 GLU 1293 -0.0080

GLU 1293 HIS 1294 0.0091

HIS 1294 THR 1295 0.0057

THR 1295 PRO 1296 0.0056

PRO 1296 VAL 1297 0.0124

VAL 1297 LEU 1298 0.0049

LEU 1298 GLU 1299 0.0068

GLU 1299 ILE 1300 0.0064

ILE 1300 LYS 1301 0.0064

LYS 1301 GLY 1302 0.0080

GLY 1302 LEU 1303 0.0108

LEU 1303 ARG 1304 0.0076

ARG 1304 ASN 1305 0.0114

ASN 1305 GLN 1306 0.0065

GLN 1306 SER 1307 0.0124

SER 1307 VAL 1308 0.0117

VAL 1308 GLY 1309 0.0672

GLY 1309 GLN 1310 0.0466

GLN 1310 MET 1311 0.0081

MET 1311 ALA 1312 0.0454

ALA 1312 PRO 1313 0.0476

PRO 1313 GLN 1314 0.0037

GLN 1314 PRO 1315 0.0434

PRO 1315 GLY 1316 0.0451

GLY 1316 ASP 1317 0.0202

ASP 1317 SER 1318 0.0278

SER 1318 SER 1319 0.0204

SER 1319 ASN 1320 0.0482

ASN 1320 ASN 1321 0.0270

ASN 1321 ASP 1322 0.0472

ASP 1322 LEU 1323 0.0302

LEU 1323 CYS 1324 0.0405

CYS 1324 PHE 1325 0.0504

PHE 1325 LYS 1326 0.0199

LYS 1326 LEU 1327 0.0216

LEU 1327 ASP 1328 0.0035

ASP 1328 TRP 1329 0.0212

TRP 1329 ALA 1330 0.0055

ALA 1330 PRO 1331 0.0192

PRO 1331 ASP 1332 0.0210

ASP 1332 ILE 1333 0.0033

ILE 1333 SER 1334 0.0190

SER 1334 SER 1335 0.0210

SER 1335 VAL 1336 0.0091

VAL 1336 LYS 1337 0.0151

LYS 1337 GLN 1338 0.0002

GLN 1338 GLU 1339 0.0207

GLU 1339 ARG 1340 0.0153

ARG 1340 LEU 1341 0.0488

LEU 1341 LYS 1342 0.0024

LYS 1342 GLU 1343 0.0430

GLU 1343 LYS 1344 0.0313

LYS 1344 PHE 1345 0.0440

PHE 1345 GLY 1346 0.0100

GLY 1346 PHE 1347 0.0173

PHE 1347 PRO 1348 0.0068

PRO 1348 LEU 1349 0.0205

LEU 1349 ASP 1350 0.0384

ASP 1350 PRO 1351 0.0004

PRO 1351 THR 1352 0.0450

THR 1352 GLU 1353 0.0279

GLU 1353 ALA 1354 0.0332

ALA 1354 ASP 1355 0.0170

ASP 1355 ILE 1356 0.0326

ILE 1356 ILE 1357 0.0254

ILE 1357 MET 1358 0.0078

MET 1358 GLY 1359 0.0483

GLY 1359 LEU 1360 0.0224

LEU 1360 ARG 1361 0.0498

ARG 1361 GLN 1362 0.0062

GLN 1362 ALA 1363 0.0484

ALA 1363 CYS 1364 0.0350

CYS 1364 ILE 1365 0.0240

ILE 1365 HIS 1366 0.0366

HIS 1366 PHE 1367 0.0276

PHE 1367 ILE 1368 0.0515

ILE 1368 HIS 1369 0.0032

HIS 1369 ARG 1370 0.0512

ARG 1370 SER 1371 0.0202

SER 1371 LEU 1372 0.0501

LEU 1372 GLN 1373 0.0008

GLN 1373 SER 1374 0.0486

SER 1374 LEU 1375 0.0270

LEU 1375 THR 1376 0.0482

THR 1376 ALA 1377 0.0480

ALA 1377 PRO 1378 0.0359

PRO 1378 ASP 1379 0.0469

ASP 1379 ARG 1380 0.0503

ARG 1380 ASP 1381 0.0426

ASP 1381 GLN 1382 0.0374

GLN 1382 LEU 1383 0.0484

LEU 1383 ASP 1384 0.0009

ASP 1384 TRP 1385 0.0470

TRP 1385 HIS 1386 0.0534

HIS 1386 GLN 1387 0.0098

GLN 1387 LYS 1388 0.0481

LYS 1388 ARG 1389 0.0645

ARG 1389 PHE 1390 0.0428

PHE 1390 TYR 1391 0.0146

TYR 1391 ASP 1392 0.0515

ASP 1392 TRP 1393 0.0497

TRP 1393 MET 1394 0.0214

MET 1394 VAL 1395 0.0342

VAL 1395 LEU 1396 0.0461

LEU 1396 GLN 1397 0.0498

GLN 1397 ILE 1398 0.0053

ILE 1398 GLN 1399 0.0512

GLN 1399 LEU 1400 0.0441

LEU 1400 ALA 1401 0.0316

ALA 1401 GLU 1402 0.0220

GLU 1402 GLU 1403 0.0465

GLU 1403 ASP 1404 0.0515

ASP 1404 ARG 1405 0.0105

ARG 1405 LEU 1406 0.0455

LEU 1406 ALA 1407 0.0415

ALA 1407 PRO 1408 0.0164

PRO 1408 ASN 1409 0.0236

ASN 1409 SER 1410 0.0351

SER 1410 SER 1411 0.0277

SER 1411 ALA 1412 0.0383

ALA 1412 TRP 1413 0.0261

TRP 1413 LEU 1414 0.0491

LEU 1414 GLN 1415 0.0087

GLN 1415 CYS 1416 0.0503

CYS 1416 SER 1417 0.0379

SER 1417 SER 1418 0.0414

SER 1418 SER 1419 0.0523

SER 1419 ASP 1420 0.0448

ASP 1420 GLU 1421 0.0178

GLU 1421 GLN 1422 0.0507

GLN 1422 LYS 1423 0.0528

LYS 1423 LEU 1424 0.0357

LEU 1424 LEU 1425 0.0311

LEU 1425 GLU 1426 0.0530

GLU 1426 ASN 1427 0.0518

ASN 1427 VAL 1428 0.0278

VAL 1428 ARG 1429 0.0423

ARG 1429 ALA 1430 0.0532

ALA 1430 SER 1431 0.0494

SER 1431 SER 1432 0.0107

SER 1432 VAL 1433 0.0288

VAL 1433 ASN 1434 0.0497

ASN 1434 GLY 1435 0.0070

GLY 1435 GLN 1436 0.0472

GLN 1436 MET 1437 0.0412

MET 1437 VAL 1438 0.0252

VAL 1438 VAL 1439 0.0288

VAL 1439 HIS 1440 0.0333

HIS 1440 VAL 1441 0.0489

VAL 1441 GLY 1442 0.0122

GLY 1442 LYS 1443 0.0387

LYS 1443 SER 1444 0.0340

SER 1444 MET 1445 0.0521

MET 1445 LEU 1446 0.0349

LEU 1446 ALA 1447 0.0394

ALA 1447 ILE 1448 0.0148

ILE 1448 LEU 1449 0.0461

LEU 1449 ARG 1450 0.0490

ARG 1450 HIS 1451 0.0079

HIS 1451 GLU 1452 0.0458

GLU 1452 ILE 1453 -0.0244

ILE 1453 ALA 1454 0.0126

ALA 1454 PRO 1455 0.0503

PRO 1455 LEU 1456 0.0100

LEU 1456 GLU 1457 0.0508

GLU 1457 LEU 1458 0.0105

LEU 1458 MET 1459 0.0432

MET 1459 LEU 1460 0.0238

LEU 1460 GLN 1461 0.0303

GLN 1461 ASP 1462 0.0510

ASP 1462 LYS 1463 0.0241

LYS 1463 LEU 1464 0.0249

LEU 1464 LEU 1465 0.0330

LEU 1465 TYR 1466 0.0277

TYR 1466 ARG 1467 0.0260

ARG 1467 TYR 1468 0.0458

TYR 1468 TYR 1469 -0.0331

TYR 1469 THR 1470 0.0432

THR 1470 ASP 1471 0.0089

ASP 1471 ALA 1472 0.0295

ALA 1472 ILE 1473 0.0375

ILE 1473 LYS 1474 0.0296

LYS 1474 TRP 1475 0.0126

TRP 1475 ASP 1476 0.0391

ASP 1476 ARG 1477 0.0434

ARG 1477 SER 1478 0.0317

SER 1478 TYR 1479 0.0243

TYR 1479 GLN 1480 0.0437

GLN 1480 GLN 1481 0.0427

GLN 1481 ILE 1482 0.0220

ILE 1482 ASP 1483 0.0372

ASP 1483 GLN 1484 0.0433

GLN 1484 LEU 1485 0.0412

LEU 1485 VAL 1486 0.0256

VAL 1486 LYS 1487 0.0284

LYS 1487 LEU 1488 0.0298

LEU 1488 HIS 1489 0.0303

HIS 1489 ALA 1490 0.0277

ALA 1490 HIS 1491 0.0274

HIS 1491 LYS 1492 0.0296

LYS 1492 CYS 1493 0.0322

CYS 1493 PRO 1494 0.0336

PRO 1494 THR 1495 0.0287

THR 1495 ALA 1496 0.0139

ALA 1496 LYS 1497 0.0321

LYS 1497 ILE 1498 0.0002

ILE 1498 ILE 1499 0.0187

ILE 1499 GLU 1500 0.0015

GLU 1500 ILE 1501 0.0256

ILE 1501 GLY 1502 0.0124

GLY 1502 ALA 1503 0.0354

ALA 1503 GLY 1504 0.0176

GLY 1504 THR 1505 0.0313

THR 1505 GLY 1506 0.0206

GLY 1506 GLY 1507 0.0211

GLY 1507 CYS 1508 0.0220

CYS 1508 THR 1509 0.0128

THR 1509 ARG 1510 0.0334

ARG 1510 ALA 1511 0.0353

ALA 1511 VAL 1512 0.0101

VAL 1512 LEU 1513 0.0271

LEU 1513 ASP 1514 0.0313

ASP 1514 ALA 1515 0.0315

ALA 1515 LEU 1516 0.0084

LEU 1516 SER 1517 -0.0082

SER 1517 ASN 1518 0.0320

ASN 1518 GLN 1519 0.0354

GLN 1519 GLY 1520 0.0375

GLY 1520 ILE 1521 0.0138

ILE 1521 ALA 1522 0.0365

ALA 1522 ARG 1523 0.0322

ARG 1523 CYS 1524 0.0374

CYS 1524 ALA 1525 0.0232

ALA 1525 GLN 1526 0.0175

GLN 1526 TYR 1527 0.0005

TYR 1527 ASP 1528 0.0321

ASP 1528 PHE 1529 0.0028

PHE 1529 THR 1530 0.0313

THR 1530 ASP 1531 0.0078

ASP 1531 VAL 1532 0.0329

VAL 1532 SER 1533 0.1052

SER 1533 SER 1534 0.0256

SER 1534 GLY 1535 0.0089

GLY 1535 PHE 1536 0.0340

PHE 1536 PHE 1537 0.0016

PHE 1537 GLU 1538 0.0341

GLU 1538 ALA 1539 0.0190

ALA 1539 ALA 1540 0.0235

ALA 1540 GLN 1541 0.0108

GLN 1541 GLN 1542 0.0265

GLN 1542 LYS 1543 0.0296

LYS 1543 PHE 1544 0.0080

PHE 1544 ALA 1545 0.0207

ALA 1545 ALA 1546 0.0301

ALA 1546 PHE 1547 0.0290

PHE 1547 ASP 1548 0.0306

ASP 1548 ASP 1549 -0.0603

ASP 1549 VAL 1550 0.0313

VAL 1550 ILE 1551 0.0125

ILE 1551 ARG 1552 0.0325

ARG 1552 PHE 1553 0.0115

PHE 1553 GLN 1554 0.0327

GLN 1554 LYS 1555 0.0193

LYS 1555 LEU 1556 0.0327

LEU 1556 ASP 1557 0.0228

ASP 1557 ILE 1558 0.0315

ILE 1558 GLU 1559 0.0294

GLU 1559 LYS 1560 0.0155

LYS 1560 ASP 1561 0.0017

ASP 1561 ILE 1562 0.0273

ILE 1562 GLU 1563 0.0063

GLU 1563 MET 1564 0.0264

MET 1564 GLN 1565 0.0557

GLN 1565 GLY 1566 0.0094

GLY 1566 PHE 1567 0.0327

PHE 1567 GLU 1568 0.0176

GLU 1568 CYS 1569 0.0308

CYS 1569 GLY 1570 0.0333

GLY 1570 SER 1571 0.0317

SER 1571 TYR 1572 0.0131

TYR 1572 ASP 1573 0.0331

ASP 1573 LEU 1574 0.0026

LEU 1574 VAL 1575 0.0184

VAL 1575 ILE 1576 0.0093

ILE 1576 ALA 1577 0.0117

ALA 1577 SER 1578 0.0088

SER 1578 GLN 1579 0.0115

GLN 1579 VAL 1580 0.0251

VAL 1580 LEU 1581 -0.0067

LEU 1581 HIS 1582 0.0045

HIS 1582 ALA 1583 0.0358

ALA 1583 THR 1584 0.0223

THR 1584 GLY 1585 0.0354

GLY 1585 LYS 1586 0.0298

LYS 1586 MET 1587 0.0355

MET 1587 GLU 1588 0.0181

GLU 1588 HIS 1589 0.0255

HIS 1589 THR 1590 0.0350

THR 1590 MET 1591 0.0340

MET 1591 ALA 1592 0.0122

ALA 1592 ASN 1593 0.0332

ASN 1593 VAL 1594 0.0337

VAL 1594 ARG 1595 0.0249

ARG 1595 LYS 1596 0.0141

LYS 1596 LEU 1597 0.0473

LEU 1597 LEU 1598 0.0360

LEU 1598 LYS 1599 0.0109

LYS 1599 PRO 1600 0.0364

PRO 1600 GLY 1601 0.0269

GLY 1601 GLY 1602 0.0319

GLY 1602 LYS 1603 0.0044

LYS 1603 LEU 1604 0.0137

LEU 1604 LEU 1605 0.0178

LEU 1605 LEU 1606 0.0093

LEU 1606 VAL 1607 0.0095

VAL 1607 GLU 1608 0.0205

GLU 1608 THR 1609 0.0014

THR 1609 THR 1610 0.0360

THR 1610 ARG 1611 0.0001

ARG 1611 ASP 1612 0.0282

ASP 1612 GLU 1613 0.0911

GLU 1613 MET 1614 0.0283

MET 1614 ASP 1615 0.0487

ASP 1615 LEU 1616 0.0028

LEU 1616 GLN 1617 0.0488

GLN 1617 LEU 1618 0.0280

LEU 1618 VAL 1619 0.0322

VAL 1619 PHE 1620 0.0153

PHE 1620 GLY 1621 0.0424

GLY 1621 LEU 1622 0.0499

LEU 1622 LEU 1623 0.0006

LEU 1623 PRO 1624 0.0385

PRO 1624 GLY 1625 0.0274

GLY 1625 TRP 1626 0.0274

TRP 1626 TRP 1627 0.0502

TRP 1627 LEU 1628 0.0056

LEU 1628 SER 1629 0.0866

SER 1629 SER 1630 0.0482

SER 1630 GLU 1631 0.0473

GLU 1631 GLU 1632 0.0100

GLU 1632 GLU 1633 0.0472

GLU 1633 ARG 1634 0.0469

ARG 1634 GLN 1635 0.0355

GLN 1635 MET 1636 0.0203

MET 1636 SER 1637 0.0332

SER 1637 PRO 1638 0.0044

PRO 1638 SER 1639 0.0487

SER 1639 LEU 1640 0.0440

LEU 1640 SER 1641 0.0420

SER 1641 THR 1642 0.0301

THR 1642 ASN 1643 0.0485

ASN 1643 SER 1644 0.0444

SER 1644 TRP 1645 0.0850

TRP 1645 GLU 1646 0.0355

GLU 1646 LYS 1647 0.0436

LYS 1647 VAL 1648 0.0394

VAL 1648 LEU 1649 0.0254

LEU 1649 LYS 1650 0.0382

LYS 1650 LYS 1651 0.0438

LYS 1651 THR 1652 0.0354

THR 1652 GLY 1653 0.0196

GLY 1653 PHE 1654 0.0362

PHE 1654 ASP 1655 0.0438

ASP 1655 GLY 1656 0.0010

GLY 1656 LEU 1657 0.0313

LEU 1657 ASP 1658 0.0348

ASP 1658 ILE 1659 0.0191

ILE 1659 GLU 1660 0.0041

GLU 1660 LEU 1661 0.0307

LEU 1661 ARG 1662 0.0061

ARG 1662 ASP 1663 0.0375

ASP 1663 CYS 1664 0.0224

CYS 1664 ASP 1665 0.0418

ASP 1665 SER 1666 0.0150

SER 1666 ASP 1667 0.0436

ASP 1667 GLU 1668 0.0201

GLU 1668 PHE 1669 0.0376

PHE 1669 TYR 1670 0.0006

TYR 1670 SER 1671 0.0375

SER 1671 PHE 1672 0.0025

PHE 1672 SER 1673 0.0206

SER 1673 VAL 1674 0.0093

VAL 1674 MET 1675 0.0292

MET 1675 MET 1676 0.0032

MET 1676 ALA 1677 0.0787

ALA 1677 THR 1678 0.0066

THR 1678 ALA 1679 0.0201

ALA 1679 SER 1680 0.0176

SER 1680 SER 1681 0.0018

SER 1681 THR 1682 0.0157

THR 1682 ILE 1683 0.0069

ILE 1683 ALA 1684 0.0113

ALA 1684 SER 1685 0.0160

SER 1685 SER 1686 0.0018

SER 1686 SER 1687 0.0108

SER 1687 MET 1688 0.0138

MET 1688 ALA 1689 0.0125

ALA 1689 PHE 1690 0.0199

PHE 1690 ALA 1691 0.0125

ALA 1691 ILE 1692 0.0199

ILE 1692 VAL 1693 0.0735

VAL 1693 TYR 1694 0.0241

TYR 1694 GLY 1695 0.0116

GLY 1695 GLU 1696 0.0150

GLU 1696 VAL 1697 0.0129

VAL 1697 PRO 1698 0.0189

PRO 1698 LEU 1699 0.0001

LEU 1699 PRO 1700 0.0195

PRO 1700 ASP 1701 0.0249

ASP 1701 GLN 1702 0.0012

GLN 1702 PHE 1703 0.0260

PHE 1703 LEU 1704 0.0195

LEU 1704 ASP 1705 0.0167

ASP 1705 ASP 1706 0.0087

ASP 1706 MET 1707 0.0220

MET 1707 LYS 1708 0.0250

LYS 1708 THR 1709 0.0183

THR 1709 ALA 1710 0.0236

ALA 1710 ILE 1711 0.0185

ILE 1711 SER 1712 0.0261

SER 1712 SER 1713 0.0012

SER 1713 SER 1714 0.0266

SER 1714 ALA 1715 0.0142

ALA 1715 VAL 1716 0.0263

VAL 1716 SER 1717 0.0052

SER 1717 ASP 1718 0.0237

ASP 1718 PRO 1719 0.0163

PRO 1719 VAL 1720 0.0016

VAL 1720 VAL 1721 0.0243

VAL 1721 GLY 1722 0.0028

GLY 1722 HIS 1723 0.0154

HIS 1723 LEU 1724 0.0252

LEU 1724 ASP 1725 0.0413

ASP 1725 SER 1726 0.0227

SER 1726 ILE 1727 0.0071

ILE 1727 ASP 1728 0.0240

ASP 1728 ALA 1729 0.0138

ALA 1729 THR 1730 0.0230

THR 1730 GLY 1731 0.0066

GLY 1731 LYS 1732 0.0171

LYS 1732 PHE 1733 0.0138

PHE 1733 CYS 1734 0.0204

CYS 1734 ILE 1735 0.0196

ILE 1735 PHE 1736 0.0118

PHE 1736 ILE 1737 0.0222

ILE 1737 GLU 1738 0.0141

GLU 1738 ASP 1739 0.0236

ASP 1739 PRO 1740 0.0206

PRO 1740 GLU 1741 0.0059

GLU 1741 THR 1742 0.0151

THR 1742 ASP 1743 0.0250

ASP 1743 ILE 1744 0.0165

ILE 1744 LEU 1745 0.0250

LEU 1745 SER 1746 0.0242

SER 1746 SER 1747 0.0027

SER 1747 PRO 1748 0.0242

PRO 1748 ASP 1749 0.0064

ASP 1749 GLU 1750 0.0196

GLU 1750 LYS 1751 0.0225

LYS 1751 SER 1752 0.0021

SER 1752 TYR 1753 0.0251

TYR 1753 ALA 1754 0.0218

ALA 1754 SER 1755 0.0144

SER 1755 ILE 1756 0.0111

ILE 1756 GLN 1757 -0.0188

GLN 1757 LYS 1758 0.0231

LYS 1758 LEU 1759 0.0031

LEU 1759 VAL 1760 0.0191

VAL 1760 THR 1761 0.0166

THR 1761 ARG 1762 0.0223

ARG 1762 CYS 1763 0.0030

CYS 1763 LYS 1764 0.0096

LYS 1764 GLY 1765 0.0176

GLY 1765 LEU 1766 0.0228

LEU 1766 ILE 1767 0.0149

ILE 1767 TRP 1768 0.0163

TRP 1768 VAL 1769 0.0184

VAL 1769 SER 1770 0.0227

SER 1770 ARG 1771 0.0194

ARG 1771 GLY 1772 0.0220

GLY 1772 GLY 1773 0.0223

GLY 1773 ALA 1774 0.0053

ALA 1774 MET 1775 0.0082

MET 1775 HIS 1776 0.0172

HIS 1776 GLY 1777 0.0012

GLY 1777 THR 1778 0.0189

THR 1778 ARG 1779 0.0061

ARG 1779 PRO 1780 0.0179

PRO 1780 ASN 1781 0.0100

ASN 1781 SER 1782 0.0102

SER 1782 SER 1783 0.0176

SER 1783 LEU 1784 0.0061

LEU 1784 LYS 1785 0.0173

LYS 1785 THR 1786 0.0050

THR 1786 GLY 1787 0.0148

GLY 1787 LEU 1788 0.0132

LEU 1788 LEU 1789 0.0319

LEU 1789 ARG 1790 0.0190

ARG 1790 THR 1791 0.0064

THR 1791 LEU 1792 0.0229

LEU 1792 ARG 1793 0.0043

ARG 1793 LEU 1794 0.0206

LEU 1794 GLU 1795 0.0054

GLU 1795 TYR 1796 0.0198

TYR 1796 THR 1797 0.0043

THR 1797 GLU 1798 0.0232

GLU 1798 LYS 1799 0.0230

LYS 1799 ARG 1800 0.0112

ARG 1800 PHE 1801 0.0205

PHE 1801 ILE 1802 0.0134

ILE 1802 SER 1803 0.0230

SER 1803 LEU 1804 0.0163

LEU 1804 ASP 1805 0.0300

ASP 1805 LEU 1806 0.0189

LEU 1806 ASP 1807 0.0188

ASP 1807 SER 1808 0.0133

SER 1808 ALA 1809 0.0120

ALA 1809 ARG 1810 0.0228

ARG 1810 PRO 1811 0.0169

PRO 1811 GLN 1812 0.0093

GLN 1812 TRP 1813 0.0226

TRP 1813 ASN 1814 0.0005

ASN 1814 HIS 1815 0.0136

HIS 1815 ASP 1816 0.0205

ASP 1816 SER 1817 0.0047

SER 1817 ILE 1818 0.0236

ILE 1818 THR 1819 0.0037

THR 1819 THR 1820 0.0219

THR 1820 ILE 1821 -0.0011

ILE 1821 ASN 1822 0.0164

ASN 1822 GLU 1823 0.0120

GLU 1823 VAL 1824 0.0094

VAL 1824 LEU 1825 0.0166

LEU 1825 CYS 1826 0.0065

CYS 1826 GLY 1827 0.0208

GLY 1827 ALA 1828 0.0019

ALA 1828 LEU 1829 0.0205

LEU 1829 ALA 1830 0.0033

ALA 1830 GLN 1831 0.0199

GLN 1831 ASN 1832 0.0209

ASN 1832 ALA 1833 0.0163

ALA 1833 ASP 1834 0.0127

ASP 1834 SER 1835 0.0207

SER 1835 SER 1836 0.0135

SER 1836 ILE 1837 0.0470

ILE 1837 LYS 1838 0.0146

LYS 1838 ASP 1839 0.0200

ASP 1839 SER 1840 0.0027

SER 1840 GLU 1841 0.0199

GLU 1841 PHE 1842 0.0140

PHE 1842 ALA 1843 0.0200

ALA 1843 GLU 1844 0.0156

GLU 1844 GLN 1845 0.0146

GLN 1845 ASP 1846 0.0131

ASP 1846 GLY 1847 0.0201

GLY 1847 GLN 1848 0.0182

GLN 1848 LEU 1849 0.0139

LEU 1849 PHE 1850 0.0202

PHE 1850 VAL 1851 0.0182

VAL 1851 PRO 1852 0.0180

PRO 1852 ARG 1853 -0.1111

ARG 1853 ILE 1854 0.0208

ILE 1854 SER 1855 0.0207

SER 1855 CYS 1856 0.0251

CYS 1856 ASP 1857 0.0188

ASP 1857 ILE 1858 0.0167

ILE 1858 ALA 1859 0.0204

ALA 1859 ARG 1860 0.0053

ARG 1860 ASN 1861 0.0224

ASN 1861 GLU 1862 0.0212

GLU 1862 ASP 1863 0.0058

ASP 1863 LEU 1864 0.0202

LEU 1864 SER 1865 0.0137

SER 1865 SER 1866 0.0259

SER 1866 ASP 1867 0.0156

ASP 1867 SER 1868 0.0120

SER 1868 ASN 1869 0.3459

ASN 1869 SER 1870 0.0003

SER 1870 PRO 1871 0.0169

PRO 1871 ALA 1872 0.0113

ALA 1872 GLN 1873 0.0028

GLN 1873 MET 1874 0.0119

MET 1874 GLU 1875 0.0090

GLU 1875 PRO 1876 0.0098

PRO 1876 PHE 1877 0.0154

PHE 1877 HIS 1878 0.0042

HIS 1878 GLN 1879 0.0174

GLN 1879 PRO 1880 0.0102

PRO 1880 GLY 1881 0.0143

GLY 1881 LYS 1882 0.0036

LYS 1882 LEU 1883 0.0084

LEU 1883 LEU 1884 0.0111

LEU 1884 GLN 1885 0.0247

GLN 1885 MET 1886 0.0154

MET 1886 GLY 1887 0.0006

GLY 1887 ILE 1888 0.0085

ILE 1888 LYS 1889 0.0093

LYS 1889 THR 1890 0.0105

THR 1890 PRO 1891 0.0193

PRO 1891 GLY 1892 0.0189

GLY 1892 LEU 1893 0.0163

LEU 1893 ILE 1894 0.0007

ILE 1894 ASP 1895 0.0195

ASP 1895 THR 1896 0.0185

THR 1896 LEU 1897 0.0047

LEU 1897 GLN 1898 0.0168

GLN 1898 PHE 1899 0.0123

PHE 1899 SER 1900 0.0177

SER 1900 LYS 1901 0.0353

LYS 1901 THR 1902 0.0149

THR 1902 ASP 1903 0.0145

ASP 1903 ALA 1904 0.0051

ALA 1904 THR 1905 0.0149

THR 1905 ASP 1906 0.0032

ASP 1906 ASN 1907 0.0147

ASN 1907 LEU 1908 0.0150

LEU 1908 PRO 1909 0.0116

PRO 1909 ASN 1910 0.0109

ASN 1910 ASP 1911 0.0153

ASP 1911 TYR 1912 0.0155

TYR 1912 ILE 1913 0.0068

ILE 1913 GLU 1914 0.0154

GLU 1914 ILE 1915 0.0137

ILE 1915 GLU 1916 0.0143

GLU 1916 PRO 1917 0.0158

PRO 1917 LYS 1918 0.0085

LYS 1918 ALA 1919 0.0097

ALA 1919 PHE 1920 0.0028

PHE 1920 GLY 1921 0.0115

GLY 1921 LEU 1922 0.0040

LEU 1922 ASN 1923 0.0076

ASN 1923 PHE 1924 0.0050

PHE 1924 ARG 1925 0.0098

ARG 1925 ASP 1926 0.0130

ASP 1926 VAL 1927 0.0111

VAL 1927 MET 1928 0.0051

MET 1928 VAL 1929 0.0133

VAL 1929 ALA 1930 0.0130

ALA 1930 MET 1931 0.0070

MET 1931 GLY 1932 0.0085

GLY 1932 GLN 1933 0.0002

GLN 1933 LEU 1934 0.0136

LEU 1934 GLU 1935 0.0106

GLU 1935 GLU 1936 0.0048

GLU 1936 SER 1937 0.0127

SER 1937 ILE 1938 0.0017

ILE 1938 MET 1939 0.0058

MET 1939 GLY 1940 0.0003

GLY 1940 PHE 1941 0.0134

PHE 1941 GLU 1942 -0.0001

GLU 1942 CYS 1943 0.0050

CYS 1943 ALA 1944 0.0001

ALA 1944 GLY 1945 0.0119

GLY 1945 VAL 1946 0.0103

VAL 1946 VAL 1947 0.0133

VAL 1947 ARG 1948 0.0143

ARG 1948 ARG 1949 0.0036

ARG 1949 VAL 1950 0.0138

VAL 1950 GLY 1951 0.0076

GLY 1951 PRO 1952 0.0127

PRO 1952 SER 1953 0.0123

SER 1953 SER 1954 0.0132

SER 1954 ALA 1955 0.0010

ALA 1955 GLY 1956 0.0145

GLY 1956 HIS 1957 0.0142

HIS 1957 ASN 1958 0.0032

ASN 1958 ILE 1959 0.0132

ILE 1959 LYS 1960 0.0098

LYS 1960 VAL 1961 0.0143

VAL 1961 GLY 1962 0.0112

GLY 1962 ASP 1963 0.0135

ASP 1963 ARG 1964 0.0138

ARG 1964 VAL 1965 -0.0072

VAL 1965 CYS 1966 0.0055

CYS 1966 ALA 1967 0.0023

ALA 1967 LEU 1968 0.0013

LEU 1968 LEU 1969 0.0097

LEU 1969 GLY 1970 0.0024

GLY 1970 GLY 1971 0.0143

GLY 1971 GLN 1972 0.0124

GLN 1972 TRP 1973 0.0109

TRP 1973 THR 1974 0.0112

THR 1974 ASN 1975 0.0032

ASN 1975 THR 1976 0.0146

THR 1976 VAL 1977 0.0128

VAL 1977 ARG 1978 0.0140

ARG 1978 VAL 1979 0.0145

VAL 1979 HIS 1980 0.0149

HIS 1980 TRP 1981 -0.0005

TRP 1981 HIS 1982 0.0122

HIS 1982 SER 1983 0.0140

SER 1983 VAL 1984 0.0008

VAL 1984 ALA 1985 0.0051

ALA 1985 PRO 1986 0.0007

PRO 1986 ILE 1987 0.0121

ILE 1987 PRO 1988 0.0026

PRO 1988 GLN 1989 0.0075

GLN 1989 ALA 1990 0.0135

ALA 1990 MET 1991 0.0012

MET 1991 ASP 1992 0.0132

ASP 1992 TRP 1993 0.0043

TRP 1993 GLU 1994 0.0112

GLU 1994 THR 1995 0.0138

THR 1995 ALA 1996 0.0132

ALA 1996 ALA 1997 -0.0287

ALA 1997 SER 1998 0.0103

SER 1998 ILE 1999 0.0103

ILE 1999 PRO 2000 0.0046

PRO 2000 ILE 2001 0.0034

ILE 2001 VAL 2002 0.0089

VAL 2002 PHE 2003 0.0082

PHE 2003 VAL 2004 0.0052

VAL 2004 THR 2005 0.0055

THR 2005 ALA 2006 0.0071

ALA 2006 TYR 2007 0.0098

TYR 2007 ILE 2008 0.0016

ILE 2008 SER 2009 0.0093

SER 2009 LEU 2010 0.0056

LEU 2010 VAL 2011 0.0084

VAL 2011 LYS 2012 0.0050

LYS 2012 ILE 2013 0.0327

ILE 2013 ALA 2014 0.0066

ALA 2014 ARG 2015 0.0022

ARG 2015 MET 2016 0.0055

MET 2016 GLN 2017 0.0030

GLN 2017 ALA 2018 0.0025

ALA 2018 GLY 2019 0.0063

GLY 2019 GLU 2020 0.0008

GLU 2020 THR 2021 0.0054

THR 2021 VAL 2022 0.0058

VAL 2022 LEU 2023 0.0044

LEU 2023 ILE 2024 0.0067

ILE 2024 HIS 2025 0.0038

HIS 2025 ALA 2026 0.0062

ALA 2026 ALA 2027 0.0007

ALA 2027 SER 2028 0.0056

SER 2028 GLY 2029 0.0238

GLY 2029 GLY 2030 0.0066

GLY 2030 VAL 2031 0.0050

VAL 2031 GLY 2032 0.0075

GLY 2032 GLN 2033 -0.0001

GLN 2033 ALA 2034 0.0076

ALA 2034 ALA 2035 0.0048

ALA 2035 ILE 2036 0.0045

ILE 2036 ILE 2037 0.0029

ILE 2037 LEU 2038 0.0059

LEU 2038 ALA 2039 0.0069

ALA 2039 LYS 2040 0.0008

LYS 2040 HIS 2041 0.0065

HIS 2041 VAL 2042 0.0040

VAL 2042 GLY 2043 0.0071

GLY 2043 ALA 2044 0.0020

ALA 2044 GLU 2045 -0.0277

GLU 2045 ILE 2046 0.0055

ILE 2046 PHE 2047 0.0030

PHE 2047 ALA 2048 0.0068

ALA 2048 THR 2049 0.0032

THR 2049 VAL 2050 0.0075

VAL 2050 GLY 2051 0.0046

GLY 2051 THR 2052 0.0047

THR 2052 ASP 2053 0.0031

ASP 2053 GLU 2054 0.0046

GLU 2054 LYS 2055 0.0071

LYS 2055 ARG 2056 0.0072

ARG 2056 ASP 2057 0.0017

ASP 2057 LEU 2058 0.0068

LEU 2058 LEU 2059 0.0073

LEU 2059 ILE 2060 0.0052

ILE 2060 LYS 2061 -0.0007

LYS 2061 GLU 2062 0.0054

GLU 2062 TYR 2063 0.0052

TYR 2063 LYS 2064 0.0055

LYS 2064 ILE 2065 0.0008

ILE 2065 PRO 2066 0.0055

PRO 2066 ASP 2067 0.0031

ASP 2067 ASP 2068 0.0041

ASP 2068 HIS 2069 0.0056

HIS 2069 ILE 2070 0.0049

ILE 2070 PHE 2071 -0.0000

PHE 2071 SER 2072 0.0028

SER 2072 SER 2073 0.0050

SER 2073 ARG 2074 0.0021

ARG 2074 ASN 2075 0.0046

ASN 2075 ALA 2076 0.0057

ALA 2076 LEU 2077 0.0242

LEU 2077 PHE 2078 0.0014

PHE 2078 ALA 2079 0.0036

ALA 2079 LYS 2080 0.0036

LYS 2080 SER 2081 0.0009

SER 2081 ILE 2082 0.0031

ILE 2082 ARG 2083 0.0035

ARG 2083 GLN 2084 0.0032

GLN 2084 ARG 2085 0.0010

ARG 2085 THR 2086 0.0036

THR 2086 ASN 2087 0.0037

ASN 2087 GLY 2088 0.0004

GLY 2088 LYS 2089 0.0031

LYS 2089 GLY 2090 0.0035

GLY 2090 VAL 2091 0.0030

VAL 2091 ASP 2092 0.0033

ASP 2092 VAL 2093 -0.0389

VAL 2093 VAL 2094 0.0021

VAL 2094 LEU 2095 0.0029

LEU 2095 ASN 2096 0.0010

ASN 2096 CYS 2097 0.0027

CYS 2097 LEU 2098 0.0021

LEU 2098 ALA 2099 0.0003

ALA 2099 GLY 2100 0.0013

GLY 2100 GLY 2101 0.0031

GLY 2101 LEU 2102 0.0001

LEU 2102 LEU 2103 0.0030

LEU 2103 GLN 2104 0.0023

GLN 2104 GLU 2105 0.0017

GLU 2105 SER 2106 0.0015

SER 2106 PHE 2107 0.0023

PHE 2107 ASP 2108 0.0030

ASP 2108 CYS 2109 -0.0151

CYS 2109 LEU 2110 0.0047

LEU 2110 ALA 2111 0.0040

ALA 2111 ASP 2112 0.0042

ASP 2112 PHE 2113 0.0040

PHE 2113 GLY 2114 0.0047

GLY 2114 ARG 2115 0.0037

ARG 2115 PHE 2116 0.0040

PHE 2116 ILE 2117 0.0045

ILE 2117 GLU 2118 0.0031

GLU 2118 ILE 2119 0.0049

ILE 2119 GLY 2120 0.0039

GLY 2120 LYS 2121 0.0001

LYS 2121 ARG 2122 0.0049

ARG 2122 ASP 2123 0.0051

ASP 2123 ILE 2124 0.0040

ILE 2124 GLU 2125 -0.0146

GLU 2125 LEU 2126 0.0031

LEU 2126 ASN 2127 0.0032

ASN 2127 HIS 2128 0.0015

HIS 2128 CYS 2129 0.0032

CYS 2129 LEU 2130 0.0015

LEU 2130 ASN 2131 0.0027

ASN 2131 MET 2132 0.0031

MET 2132 GLY 2133 0.0016

GLY 2133 MET 2134 0.0022

MET 2134 PHE 2135 0.0020

PHE 2135 ALA 2136 0.0030

ALA 2136 ARG 2137 0.0006

ARG 2137 SER 2138 0.0026

SER 2138 ALA 2139 0.0031

ALA 2139 THR 2140 0.0023

THR 2140 PHE 2141 0.0477

PHE 2141 THR 2142 0.0075

THR 2142 ALA 2143 0.0075

ALA 2143 VAL 2144 0.0051

VAL 2144 ASP 2145 0.0070

ASP 2145 LEU 2146 0.0052

LEU 2146 ILE 2147 0.0038

ILE 2147 ALA 2148 0.0037

ALA 2148 ILE 2149 0.0042

ILE 2149 GLY 2150 0.0071

GLY 2150 ARG 2151 0.0006

ARG 2151 ASP 2152 0.0065

ASP 2152 ARG 2153 0.0023

ARG 2153 SER 2154 0.0041

SER 2154 TYR 2155 0.0061

TYR 2155 MET 2156 0.0061

MET 2156 PHE 2157 0.0240

PHE 2157 ALA 2158 0.0078

ALA 2158 GLU 2159 0.0112

GLU 2159 ALA 2160 0.0118

ALA 2160 LEU 2161 0.0094

LEU 2161 PRO 2162 0.0044

PRO 2162 LYS 2163 0.0117

LYS 2163 ILE 2164 0.0116

ILE 2164 MET 2165 0.0060

MET 2165 THR 2166 0.0079

THR 2166 LEU 2167 0.0115

LEU 2167 LEU 2168 0.0110

LEU 2168 GLN 2169 0.0049

GLN 2169 GLU 2170 0.0105

GLU 2170 LYS 2171 0.0115

LYS 2171 ALA 2172 0.0079

ALA 2172 ILE 2173 0.0257

ILE 2173 ARG 2174 0.0135

ARG 2174 PRO 2175 0.0090

PRO 2175 VAL 2176 0.0072

VAL 2176 THR 2177 0.0126

THR 2177 PRO 2178 0.0134

PRO 2178 ILE 2179 0.0131

ILE 2179 SER 2180 0.0111

SER 2180 ILE 2181 0.0130

ILE 2181 TYR 2182 0.0087

TYR 2182 LYS 2183 0.0134

LYS 2183 ILE 2184 0.0056

ILE 2184 GLY 2185 0.0131

GLY 2185 ASP 2186 0.0130

ASP 2186 ILE 2187 0.0084

ILE 2187 GLU 2188 0.0058

GLU 2188 THR 2189 0.0670

THR 2189 ALA 2190 0.0112

ALA 2190 PHE 2191 0.0005

PHE 2191 ARG 2192 0.0109

ARG 2192 LEU 2193 0.0052

LEU 2193 MET 2194 0.0097

MET 2194 GLN 2195 0.0015

GLN 2195 ALA 2196 0.0104

ALA 2196 GLY 2197 0.0101

GLY 2197 LYS 2198 0.0030

LYS 2198 HIS 2199 0.0070

HIS 2199 MET 2200 0.0076

MET 2200 GLY 2201 0.0104

GLY 2201 LYS 2202 0.0110

LYS 2202 ILE 2203 0.0113

ILE 2203 VAL 2204 0.0093

VAL 2204 ILE 2205 0.1408

ILE 2205 THR 2206 0.0010

THR 2206 ALA 2207 0.0113

ALA 2207 PRO 2208 0.0027

PRO 2208 GLU 2209 0.0092

GLU 2209 ASP 2210 0.0116

ASP 2210 ALA 2211 0.0005

ALA 2211 MET 2212 0.0078

MET 2212 VAL 2213 0.0019

VAL 2213 PRO 2214 0.0053

PRO 2214 VAL 2215 0.0123

VAL 2215 ILE 2216 0.0073

ILE 2216 THR 2217 0.0106

THR 2217 ARG 2218 0.0068

ARG 2218 PRO 2219 0.0123

PRO 2219 PRO 2220 0.0108

PRO 2220 LYS 2221 0.2060

LYS 2221 LEU 2222 0.0069

LEU 2222 GLN 2223 0.0049

GLN 2223 LEU 2224 0.0057

LEU 2224 ARG 2225 0.0058

ARG 2225 PRO 2226 0.0061

PRO 2226 ASP 2227 0.0095

ASP 2227 ALA 2228 0.0142

ALA 2228 SER 2229 0.0151

SER 2229 TYR 2230 0.0061

TYR 2230 LEU 2231 0.0148

LEU 2231 ILE 2232 0.0120

ILE 2232 VAL 2233 0.0152

VAL 2233 GLY 2234 0.0150

GLY 2234 GLY 2235 0.0148

GLY 2235 LEU 2236 0.0141

LEU 2236 GLY 2237 -0.0437

GLY 2237 GLY 2238 0.0073

GLY 2238 ILE 2239 0.0149

ILE 2239 GLY 2240 0.0011

GLY 2240 ARG 2241 0.0149

ARG 2241 SER 2242 0.0069

SER 2242 LEU 2243 0.0140

LEU 2243 CYS 2244 0.0024

CYS 2244 LYS 2245 0.0139

LYS 2245 ASN 2246 0.0107

ASN 2246 PHE 2247 0.0070

PHE 2247 VAL 2248 0.0091

VAL 2248 GLU 2249 0.0085

GLU 2249 ASN 2250 0.0156

ASN 2250 GLY 2251 0.0007

GLY 2251 ALA 2252 0.0128

ALA 2252 ARG 2253 -0.0279

ARG 2253 SER 2254 0.0130

SER 2254 LEU 2255 0.0115

LEU 2255 VAL 2256 0.0134

VAL 2256 LEU 2257 0.0122

LEU 2257 LEU 2258 0.0143

LEU 2258 SER 2259 0.0139

SER 2259 ARG 2260 0.0133

ARG 2260 ASN 2261 0.0123

ASN 2261 ALA 2262 0.0122

ALA 2262 ASN 2263 0.0087

ASN 2263 VAL 2264 0.0076

VAL 2264 SER 2265 0.0123

SER 2265 GLN 2266 0.0139

GLN 2266 GLN 2267 0.0000

GLN 2267 SER 2268 0.0143

SER 2268 GLY 2269 -0.0254

GLY 2269 GLU 2270 0.0097

GLU 2270 PHE 2271 0.0119

PHE 2271 LEU 2272 0.0026

LEU 2272 ASP 2273 0.0115

ASP 2273 GLU 2274 0.0055

GLU 2274 LEU 2275 0.0128

LEU 2275 ARG 2276 0.0004

ARG 2276 SER 2277 0.0132

SER 2277 THR 2278 0.0122

THR 2278 GLY 2279 0.0024

GLY 2279 CYS 2280 0.0120

CYS 2280 ILE 2281 0.0084

ILE 2281 VAL 2282 0.0099

VAL 2282 GLY 2283 0.0115

GLY 2283 VAL 2284 0.0104

VAL 2284 VAL 2285 0.1391

VAL 2285 ASP 2286 0.0157

ASP 2286 CYS 2287 0.0123

CYS 2287 ASP 2288 0.0102

ASP 2288 ILE 2289 0.0111

ILE 2289 SER 2290 0.0149

SER 2290 SER 2291 0.0013

SER 2291 LYS 2292 0.0153

LYS 2292 THR 2293 0.0005

THR 2293 GLN 2294 0.0154

GLN 2294 VAL 2295 0.0092

VAL 2295 GLU 2296 0.0096

GLU 2296 ALA 2297 0.0064

ALA 2297 THR 2298 0.0106

THR 2298 MET 2299 0.0144

MET 2299 LEU 2300 0.0019

LEU 2300 ARG 2301 0.0482

ARG 2301 LEU 2302 0.0056

LEU 2302 LYS 2303 0.0141

LYS 2303 LYS 2304 0.0039

LYS 2304 ASP 2305 0.0138

ASP 2305 MET 2306 0.0023

MET 2306 LEU 2307 0.0109

LEU 2307 PRO 2308 0.0119

PRO 2308 ILE 2309 0.0066

ILE 2309 ARG 2310 0.0038

ARG 2310 GLY 2311 0.0081

GLY 2311 ILE 2312 0.0147

ILE 2312 VAL 2313 0.0089

VAL 2313 HIS 2314 0.0148

HIS 2314 ALA 2315 0.0130

ALA 2315 GLY 2316 0.0106

GLY 2316 MET 2317 0.0511

MET 2317 VAL 2318 0.0110

VAL 2318 LEU 2319 0.0164

LEU 2319 GLN 2320 0.0135

GLN 2320 ASP 2321 0.0117

ASP 2321 SER 2322 0.0177

SER 2322 VAL 2323 0.0117

VAL 2323 PHE 2324 0.0179

PHE 2324 GLU 2325 0.0142

GLU 2325 ARG 2326 0.0073

ARG 2326 MET 2327 0.0181

MET 2327 SER 2328 0.0053

SER 2328 LEU 2329 0.0181

LEU 2329 ASP 2330 0.0136

ASP 2330 ASP 2331 0.0100

ASP 2331 TYR 2332 0.0085

TYR 2332 ASN 2333 0.0782

ASN 2333 THR 2334 0.0109

THR 2334 ALA 2335 0.0013

ALA 2335 ILE 2336 0.0106

ILE 2336 ARG 2337 0.0041

ARG 2337 PRO 2338 0.0111

PRO 2338 LYS 2339 0.0011

LYS 2339 VAL 2340 0.0113

VAL 2340 GLN 2341 0.0019

GLN 2341 GLY 2342 0.0115

GLY 2342 SER 2343 0.0028

SER 2343 TRP 2344 0.0110

TRP 2344 ASN 2345 0.0017

ASN 2345 LEU 2346 0.0096

LEU 2346 HIS 2347 0.0061

HIS 2347 SER 2348 0.0056

SER 2348 GLY 2349 0.0489

GLY 2349 LEU 2350 0.0101

LEU 2350 SER 2351 0.0155

SER 2351 ASP 2352 0.0117

ASP 2352 CYS 2353 0.0124

CYS 2353 ASP 2354 0.0059

ASP 2354 LEU 2355 0.0114

LEU 2355 ASP 2356 0.0054

ASP 2356 PHE 2357 0.0152

PHE 2357 PHE 2358 0.0151

PHE 2358 ILE 2359 0.0124

ILE 2359 MET 2360 0.0161

MET 2360 LEU 2361 0.0142

LEU 2361 SER 2362 0.0144

SER 2362 SER 2363 0.0109

SER 2363 LEU 2364 0.0011

LEU 2364 ALA 2365 -0.0114

ALA 2365 GLY 2366 0.0183

GLY 2366 VAL 2367 0.0001

VAL 2367 SER 2368 0.0180

SER 2368 GLY 2369 0.0066

GLY 2369 SER 2370 0.0117

SER 2370 ALA 2371 0.0149

ALA 2371 SER 2372 0.0003

SER 2372 GLN 2373 0.0183

GLN 2373 ALA 2374 0.0182

ALA 2374 ASN 2375 0.0097

ASN 2375 TYR 2376 0.0158

TYR 2376 THR 2377 0.0024

THR 2377 ALA 2378 0.0168

ALA 2378 GLY 2379 0.0153

GLY 2379 GLY 2380 0.0052

GLY 2380 ALA 2381 0.0072

ALA 2381 TYR 2382 0.0080

TYR 2382 GLN 2383 0.0161

GLN 2383 ASP 2384 0.0002

ASP 2384 ALA 2385 0.0159

ALA 2385 LEU 2386 0.0078

LEU 2386 ALA 2387 0.0101

ALA 2387 LYS 2388 0.0088

LYS 2388 TYR 2389 0.0081

TYR 2389 ARG 2390 0.0143

ARG 2390 ARG 2391 0.0021

ARG 2391 ALA 2392 0.0154

ALA 2392 GLN 2393 0.0059

GLN 2393 GLY 2394 0.0139

GLY 2394 LEU 2395 0.0088

LEU 2395 SER 2396 0.0157

SER 2396 ALA 2397 -0.0273

ALA 2397 VAL 2398 0.0071

VAL 2398 SER 2399 0.0153

SER 2399 ILE 2400 0.0109

ILE 2400 ASP 2401 0.0139

ASP 2401 LEU 2402 0.0157

LEU 2402 GLY 2403 0.0086

GLY 2403 MET 2404 0.0154

MET 2404 VAL 2405 0.0142

VAL 2405 GLN 2406 0.0134

GLN 2406 SER 2407 0.0112

SER 2407 VAL 2408 0.0024

VAL 2408 GLY 2409 0.0101

GLY 2409 TYR 2410 0.0155

TYR 2410 VAL 2411 0.0010

VAL 2411 ALA 2412 0.0154

ALA 2412 GLU 2413 0.0591

GLU 2413 THR 2414 0.0183

THR 2414 LYS 2415 0.0128

LYS 2415 GLY 2416 0.0089

GLY 2416 VAL 2417 0.0191

VAL 2417 ALA 2418 0.0073

ALA 2418 GLU 2419 0.0115

GLU 2419 ARG 2420 0.0175

ARG 2420 LEU 2421 0.0183

LEU 2421 VAL 2422 0.0034

VAL 2422 ARG 2423 0.0178

ARG 2423 MET 2424 0.0171

MET 2424 GLY 2425 0.0113

GLY 2425 TYR 2426 0.0119

TYR 2426 SER 2427 0.0164

SER 2427 PRO 2428 0.0128

PRO 2428 ILE 2429 0.0452

ILE 2429 SER 2430 0.0098

SER 2430 GLU 2431 0.0024

GLU 2431 MET 2432 0.0092

MET 2432 GLU 2433 0.0083

GLU 2433 VAL 2434 0.0036

VAL 2434 LEU 2435 0.0094

LEU 2435 LYS 2436 0.0044

LYS 2436 ILE 2437 0.0115

ILE 2437 VAL 2438 0.0007

VAL 2438 GLU 2439 0.0115

GLU 2439 HIS 2440 0.0049

HIS 2440 ALA 2441 0.0083

ALA 2441 ILE 2442 0.0063

ILE 2442 THR 2443 0.0072

THR 2443 ASN 2444 0.0061

ASN 2444 PRO 2445 0.0950

PRO 2445 PRO 2446 0.0127

PRO 2446 PRO 2447 0.0150

PRO 2447 GLU 2448 0.0158

GLU 2448 ALA 2449 0.0053

ALA 2449 SER 2450 0.0119

SER 2450 SER 2451 0.0154

SER 2451 ALA 2452 0.0013

ALA 2452 GLN 2453 0.0162

GLN 2453 ILE 2454 0.0139

ILE 2454 ILE 2455 0.0162

ILE 2455 THR 2456 0.0163

THR 2456 GLY 2457 0.0163

GLY 2457 ILE 2458 0.0095

ILE 2458 SER 2459 0.0091

SER 2459 THR 2460 0.0012

THR 2460 LYS 2461 0.0979

LYS 2461 PRO 2462 0.0134

PRO 2462 GLY 2463 0.0071

GLY 2463 ARG 2464 0.0108

ARG 2464 HIS 2465 0.0102

HIS 2465 TRP 2466 0.0080

TRP 2466 THR 2467 0.0154

THR 2467 GLU 2468 0.0009

GLU 2468 SER 2469 0.0132

SER 2469 SER 2470 0.0148

SER 2470 TRP 2471 0.0154

TRP 2471 LEU 2472 0.0023

LEU 2472 GLN 2473 0.0141

GLN 2473 ASP 2474 0.0143

ASP 2474 ALA 2475 0.0064

ALA 2475 ARG 2476 0.0143

ARG 2476 PHE 2477 0.0109

PHE 2477 ALA 2478 0.0056

ALA 2478 THR 2479 0.0090

THR 2479 LEU 2480 0.0114

LEU 2480 ARG 2481 0.0150

ARG 2481 GLU 2482 -0.0001

GLU 2482 ARG 2483 0.0149

ARG 2483 ALA 2484 0.0097

ALA 2484 ARG 2485 0.0098

ARG 2485 ASP 2486 0.0046

ASP 2486 VAL 2487 0.0124

VAL 2487 LYS 2488 0.0147

LYS 2488 GLU 2489 0.0024

GLU 2489 LEU 2490 0.0123

LEU 2490 SER 2491 0.0115

SER 2491 ASN 2492 0.0117

ASN 2492 SER 2493 -0.0323

SER 2493 GLN 2494 0.0095

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** sdgklnrdh ***

CA strain for 22101813491974862

--- normal mode 13 ---

Should you encounter any unexpected behaviour,
please let us know.

* sdgklnrdh *