Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE/HYDROLASE INHIBITOR 04-OCT-16 5H08 *

CA strain for 2502261434124124660

--- normal mode 9 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
GLY 1696 PRO 1697 -0.0002

PRO 1697 ALA 1698 0.0206

ALA 1698 ILE 1699 0.0003

ILE 1699 PRO 1700 0.0242

PRO 1700 ILE 1701 0.0002

ILE 1701 LYS 1702 0.0202

LYS 1702 HIS 1703 -0.0004

HIS 1703 PHE 1704 0.0123

PHE 1704 PRO 1705 -0.0000

PRO 1705 LYS 1706 0.0496

LYS 1706 HIS 1707 0.0004

HIS 1707 VAL 1708 0.0217

VAL 1708 ALA 1709 0.0001

ALA 1709 ASP 1710 0.0439

ASP 1710 LEU 1711 -0.0000

LEU 1711 HIS 1712 -0.0158

HIS 1712 ALA 1713 -0.0003

ALA 1713 SER 1714 0.1083

SER 1714 SER 1715 -0.0001

SER 1715 GLY 1716 -0.1305

GLY 1716 PHE 1717 -0.0001

PHE 1717 THR 1718 -0.0086

THR 1718 GLU 1719 -0.0003

GLU 1719 GLU 1720 0.0289

GLU 1720 PHE 1721 0.0001

PHE 1721 GLU 1722 0.0353

GLU 1722 GLU 1730 0.0141

GLU 1730 VAL 1731 -0.0002

VAL 1731 GLN 1732 -0.0142

GLN 1732 SER 1733 0.0002

SER 1733 CYS 1734 0.2009

CYS 1734 THR 1735 0.0002

THR 1735 VAL 1736 -0.0502

VAL 1736 ASP 1737 0.0003

ASP 1737 LEU 1738 0.0701

LEU 1738 GLY 1739 0.0003

GLY 1739 ILE 1740 0.2150

ILE 1740 THR 1741 0.0001

THR 1741 ALA 1742 0.0824

ALA 1742 ASP 1743 0.0000

ASP 1743 SER 1744 -0.0434

SER 1744 SER 1745 0.0000

SER 1745 ASN 1746 -0.0050

ASN 1746 HIS 1747 0.0002

HIS 1747 PRO 1748 0.0874

PRO 1748 ASP 1749 0.0004

ASP 1749 ASN 1750 -0.0179

ASN 1750 LYS 1751 -0.0001

LYS 1751 HIS 1752 0.0256

HIS 1752 LYS 1753 0.0001

LYS 1753 ASN 1754 0.0603

ASN 1754 ARG 1755 0.0001

ARG 1755 TYR 1756 0.0785

TYR 1756 ILE 1757 -0.0002

ILE 1757 ASN 1758 -0.0704

ASN 1758 ILE 1759 0.0004

ILE 1759 VAL 1760 0.0636

VAL 1760 ALA 1761 0.0001

ALA 1761 TYR 1762 0.1108

TYR 1762 ASP 1763 -0.0002

ASP 1763 HIS 1764 0.1211

HIS 1764 SER 1765 0.0003

SER 1765 ARG 1766 -0.1395

ARG 1766 VAL 1767 -0.0000

VAL 1767 LYS 1768 0.0065

LYS 1768 LEU 1769 -0.0001

LEU 1769 ALA 1770 -0.1504

ALA 1770 GLN 1771 -0.0001

GLN 1771 LEU 1772 -0.2636

LEU 1772 ALA 1773 -0.0000

ALA 1773 GLU 1774 -0.2044

GLU 1774 LYS 1775 0.0002

LYS 1775 ASP 1776 0.0464

ASP 1776 GLY 1777 0.0001

GLY 1777 LYS 1778 0.0122

LYS 1778 LEU 1779 0.0001

LEU 1779 THR 1780 0.1846

THR 1780 ASP 1781 -0.0002

ASP 1781 TYR 1782 -0.0877

TYR 1782 ILE 1783 -0.0002

ILE 1783 ASN 1784 -0.0453

ASN 1784 ALA 1785 -0.0003

ALA 1785 ASN 1786 0.0672

ASN 1786 TYR 1787 0.0002

TYR 1787 VAL 1788 0.0036

VAL 1788 ASP 1789 -0.0001

ASP 1789 GLY 1790 0.1300

GLY 1790 TYR 1791 -0.0001

TYR 1791 ASN 1792 -0.0624

ASN 1792 ARG 1793 -0.0001

ARG 1793 PRO 1794 0.0773

PRO 1794 LYS 1795 -0.0003

LYS 1795 ALA 1796 -0.0125

ALA 1796 TYR 1797 -0.0001

TYR 1797 ILE 1798 0.0567

ILE 1798 ALA 1799 -0.0001

ALA 1799 ALA 1800 0.0306

ALA 1800 GLN 1801 0.0003

GLN 1801 GLY 1802 0.0446

GLY 1802 PRO 1803 -0.0001

PRO 1803 LEU 1804 0.0060

LEU 1804 LYS 1805 0.0001

LYS 1805 SER 1806 0.0445

SER 1806 THR 1807 0.0002

THR 1807 ALA 1808 0.1138

ALA 1808 GLU 1809 0.0004

GLU 1809 ASP 1810 0.0268

ASP 1810 PHE 1811 -0.0000

PHE 1811 TRP 1812 0.0051

TRP 1812 ARG 1813 -0.0001

ARG 1813 MET 1814 0.0124

MET 1814 ILE 1815 0.0001

ILE 1815 TRP 1816 -0.0100

TRP 1816 GLU 1817 -0.0002

GLU 1817 HIS 1818 0.0047

HIS 1818 ASN 1819 0.0002

ASN 1819 VAL 1820 0.0419

VAL 1820 GLU 1821 0.0004

GLU 1821 VAL 1822 0.0789

VAL 1822 ILE 1823 -0.0001

ILE 1823 VAL 1824 0.0573

VAL 1824 MET 1825 -0.0001

MET 1825 ILE 1826 0.0594

ILE 1826 THR 1827 0.0002

THR 1827 ASN 1828 0.0243

ASN 1828 LEU 1829 -0.0000

LEU 1829 VAL 1830 -0.0380

VAL 1830 GLU 1831 -0.0002

GLU 1831 LYS 1832 -0.0081

LYS 1832 GLY 1833 -0.0002

GLY 1833 ARG 1834 0.2056

ARG 1834 ARG 1835 -0.0003

ARG 1835 LYS 1836 0.0741

LYS 1836 CYS 1837 -0.0001

CYS 1837 ASP 1838 0.0367

ASP 1838 GLN 1839 -0.0002

GLN 1839 TYR 1840 -0.0414

TYR 1840 TRP 1841 0.0000

TRP 1841 PRO 1842 0.0330

PRO 1842 ALA 1843 0.0003

ALA 1843 ASP 1844 0.0569

ASP 1844 GLY 1845 -0.0002

GLY 1845 SER 1846 -0.0014

SER 1846 GLU 1847 -0.0000

GLU 1847 GLU 1848 0.0223

GLU 1848 TYR 1849 -0.0000

TYR 1849 GLY 1850 -0.0483

GLY 1850 ASN 1851 -0.0003

ASN 1851 PHE 1852 0.0319

PHE 1852 LEU 1853 -0.0004

LEU 1853 VAL 1854 0.0649

VAL 1854 THR 1855 0.0000

THR 1855 GLN 1856 0.0713

GLN 1856 LYS 1857 0.0002

LYS 1857 SER 1858 0.1264

SER 1858 VAL 1859 -0.0002

VAL 1859 GLN 1860 0.0717

GLN 1860 VAL 1861 -0.0004

VAL 1861 LEU 1862 0.0505

LEU 1862 ALA 1863 0.0000

ALA 1863 TYR 1864 0.0311

TYR 1864 TYR 1865 -0.0003

TYR 1865 THR 1866 0.1259

THR 1866 VAL 1867 -0.0002

VAL 1867 ARG 1868 0.1045

ARG 1868 ASN 1869 -0.0001

ASN 1869 PHE 1870 0.1471

PHE 1870 THR 1871 0.0003

THR 1871 LEU 1872 0.0591

LEU 1872 ARG 1873 -0.0001

ARG 1873 ASN 1874 0.0773

ASN 1874 THR 1875 0.0003

THR 1875 LYS 1876 0.1395

LYS 1876 ILE 1877 -0.0003

ILE 1877 ARG 1889 0.1107

ARG 1889 VAL 1890 -0.0002

VAL 1890 VAL 1891 0.0788

VAL 1891 THR 1892 0.0003

THR 1892 GLN 1893 0.0471

GLN 1893 TYR 1894 -0.0002

TYR 1894 HIS 1895 -0.0431

HIS 1895 TYR 1896 -0.0002

TYR 1896 THR 1897 -0.0220

THR 1897 GLN 1898 -0.0004

GLN 1898 TRP 1899 0.0381

TRP 1899 PRO 1900 -0.0003

PRO 1900 ASP 1901 -0.0821

ASP 1901 MET 1902 -0.0003

MET 1902 GLY 1903 0.0629

GLY 1903 VAL 1904 -0.0000

VAL 1904 PRO 1905 -0.0533

PRO 1905 GLU 1906 -0.0002

GLU 1906 TYR 1907 -0.0004

TYR 1907 SER 1908 0.0004

SER 1908 LEU 1909 0.0118

LEU 1909 PRO 1910 -0.0003

PRO 1910 VAL 1911 0.0879

VAL 1911 LEU 1912 -0.0003

LEU 1912 THR 1913 0.0901

THR 1913 PHE 1914 -0.0000

PHE 1914 VAL 1915 -0.0643

VAL 1915 ARG 1916 -0.0000

ARG 1916 LYS 1917 0.0409

LYS 1917 ALA 1918 0.0001

ALA 1918 ALA 1919 -0.1525

ALA 1919 TYR 1920 0.0001

TYR 1920 ALA 1921 0.0549

ALA 1921 LYS 1922 0.0001

LYS 1922 ARG 1923 -0.0715

ARG 1923 HIS 1924 -0.0002

HIS 1924 ALA 1925 0.0465

ALA 1925 VAL 1926 0.0001

VAL 1926 GLY 1927 0.0908

GLY 1927 PRO 1928 -0.0002

PRO 1928 VAL 1929 0.0327

VAL 1929 VAL 1930 0.0001

VAL 1930 VAL 1931 0.0333

VAL 1931 HIS 1932 0.0002

HIS 1932 CYS 1933 -0.0126

CYS 1933 SER 1934 0.0000

SER 1934 ALA 1935 0.0507

ALA 1935 GLY 1936 0.0001

GLY 1936 VAL 1937 0.0851

VAL 1937 GLY 1938 -0.0001

GLY 1938 ARG 1939 0.0797

ARG 1939 THR 1940 0.0002

THR 1940 GLY 1941 0.0033

GLY 1941 THR 1942 -0.0001

THR 1942 TYR 1943 0.1042

TYR 1943 ILE 1944 0.0001

ILE 1944 VAL 1945 -0.0025

VAL 1945 LEU 1946 -0.0000

LEU 1946 ASP 1947 0.0725

ASP 1947 SER 1948 -0.0001

SER 1948 MET 1949 -0.0222

MET 1949 LEU 1950 0.0001

LEU 1950 GLN 1951 0.0169

GLN 1951 GLN 1952 0.0001

GLN 1952 ILE 1953 0.0572

ILE 1953 GLN 1954 0.0002

GLN 1954 HIS 1955 0.0113

HIS 1955 GLU 1956 0.0002

GLU 1956 GLY 1957 0.0201

GLY 1957 THR 1958 -0.0001

THR 1958 VAL 1959 0.0291

VAL 1959 ASN 1960 0.0004

ASN 1960 ILE 1961 0.0292

ILE 1961 PHE 1962 0.0000

PHE 1962 GLY 1963 -0.0370

GLY 1963 PHE 1964 -0.0004

PHE 1964 LEU 1965 0.0569

LEU 1965 LYS 1966 0.0004

LYS 1966 HIS 1967 -0.1993

HIS 1967 ILE 1968 0.0001

ILE 1968 ARG 1969 -0.0351

ARG 1969 SER 1970 0.0002

SER 1970 GLN 1971 -0.1228

GLN 1971 ARG 1972 -0.0001

ARG 1972 ASN 1973 0.0465

ASN 1973 TYR 1974 0.0003

TYR 1974 LEU 1975 -0.0381

LEU 1975 VAL 1976 0.0002

VAL 1976 GLN 1977 0.0051

GLN 1977 THR 1978 0.0003

THR 1978 GLU 1979 -0.0686

GLU 1979 GLU 1980 -0.0001

GLU 1980 GLN 1981 0.0549

GLN 1981 TYR 1982 -0.0000

TYR 1982 VAL 1983 -0.0220

VAL 1983 PHE 1984 -0.0003

PHE 1984 ILE 1985 -0.0127

ILE 1985 HIS 1986 0.0000

HIS 1986 ASP 1987 0.0084

ASP 1987 THR 1988 0.0002

THR 1988 LEU 1989 0.0050

LEU 1989 VAL 1990 -0.0001

VAL 1990 GLU 1991 0.1311

GLU 1991 ALA 1992 0.0003

ALA 1992 ILE 1993 -0.0347

ILE 1993 LEU 1994 -0.0001

LEU 1994 SER 1995 -0.0271

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 8th, 2025.

Should you encounter any unexpected behaviour, please let us know.

*** HYDROLASE/HYDROLASE INHIBITOR 04-OCT-16 5H08 ***

CA strain for 2502261434124124660

--- normal mode 9 ---

Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE/HYDROLASE INHIBITOR 04-OCT-16 5H08 *