Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE/HYDROLASE INHIBITOR 04-OCT-16 5H08 *

CA strain for 2502261434124124660

--- normal mode 11 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
GLY 1696 PRO 1697 0.0001

PRO 1697 ALA 1698 0.0620

ALA 1698 ILE 1699 -0.0002

ILE 1699 PRO 1700 0.0366

PRO 1700 ILE 1701 0.0001

ILE 1701 LYS 1702 0.0165

LYS 1702 HIS 1703 0.0000

HIS 1703 PHE 1704 -0.0159

PHE 1704 PRO 1705 0.0001

PRO 1705 LYS 1706 0.0529

LYS 1706 HIS 1707 0.0001

HIS 1707 VAL 1708 0.0036

VAL 1708 ALA 1709 -0.0001

ALA 1709 ASP 1710 0.0448

ASP 1710 LEU 1711 -0.0002

LEU 1711 HIS 1712 -0.0140

HIS 1712 ALA 1713 -0.0003

ALA 1713 SER 1714 0.1248

SER 1714 SER 1715 -0.0004

SER 1715 GLY 1716 -0.1369

GLY 1716 PHE 1717 0.0002

PHE 1717 THR 1718 -0.0194

THR 1718 GLU 1719 -0.0001

GLU 1719 GLU 1720 0.0259

GLU 1720 PHE 1721 0.0000

PHE 1721 GLU 1722 0.0331

GLU 1722 GLU 1730 0.0300

GLU 1730 VAL 1731 -0.0002

VAL 1731 GLN 1732 0.0426

GLN 1732 SER 1733 0.0001

SER 1733 CYS 1734 0.0183

CYS 1734 THR 1735 0.0000

THR 1735 VAL 1736 0.1055

VAL 1736 ASP 1737 0.0000

ASP 1737 LEU 1738 -0.0266

LEU 1738 GLY 1739 0.0000

GLY 1739 ILE 1740 -0.0693

ILE 1740 THR 1741 0.0003

THR 1741 ALA 1742 0.0078

ALA 1742 ASP 1743 -0.0001

ASP 1743 SER 1744 -0.0557

SER 1744 SER 1745 0.0001

SER 1745 ASN 1746 0.0181

ASN 1746 HIS 1747 0.0000

HIS 1747 PRO 1748 0.0856

PRO 1748 ASP 1749 0.0003

ASP 1749 ASN 1750 0.1100

ASN 1750 LYS 1751 -0.0002

LYS 1751 HIS 1752 -0.1954

HIS 1752 LYS 1753 -0.0003

LYS 1753 ASN 1754 0.0039

ASN 1754 ARG 1755 -0.0000

ARG 1755 TYR 1756 -0.1231

TYR 1756 ILE 1757 0.0003

ILE 1757 ASN 1758 0.1003

ASN 1758 ILE 1759 0.0002

ILE 1759 VAL 1760 -0.0299

VAL 1760 ALA 1761 0.0000

ALA 1761 TYR 1762 -0.0648

TYR 1762 ASP 1763 0.0001

ASP 1763 HIS 1764 0.0737

HIS 1764 SER 1765 -0.0001

SER 1765 ARG 1766 -0.0298

ARG 1766 VAL 1767 -0.0001

VAL 1767 LYS 1768 -0.1262

LYS 1768 LEU 1769 -0.0003

LEU 1769 ALA 1770 -0.1014

ALA 1770 GLN 1771 0.0002

GLN 1771 LEU 1772 -0.1679

LEU 1772 ALA 1773 -0.0000

ALA 1773 GLU 1774 0.1502

GLU 1774 LYS 1775 0.0002

LYS 1775 ASP 1776 0.2091

ASP 1776 GLY 1777 0.0001

GLY 1777 LYS 1778 0.0631

LYS 1778 LEU 1779 0.0001

LEU 1779 THR 1780 -0.3797

THR 1780 ASP 1781 0.0001

ASP 1781 TYR 1782 0.0937

TYR 1782 ILE 1783 -0.0001

ILE 1783 ASN 1784 0.0029

ASN 1784 ALA 1785 -0.0003

ALA 1785 ASN 1786 0.0219

ASN 1786 TYR 1787 0.0001

TYR 1787 VAL 1788 -0.0480

VAL 1788 ASP 1789 -0.0002

ASP 1789 GLY 1790 0.1505

GLY 1790 TYR 1791 0.0001

TYR 1791 ASN 1792 -0.0829

ASN 1792 ARG 1793 0.0003

ARG 1793 PRO 1794 0.0834

PRO 1794 LYS 1795 0.0002

LYS 1795 ALA 1796 -0.0393

ALA 1796 TYR 1797 -0.0001

TYR 1797 ILE 1798 -0.0211

ILE 1798 ALA 1799 -0.0002

ALA 1799 ALA 1800 -0.0193

ALA 1800 GLN 1801 0.0003

GLN 1801 GLY 1802 -0.0190

GLY 1802 PRO 1803 -0.0002

PRO 1803 LEU 1804 -0.0240

LEU 1804 LYS 1805 0.0005

LYS 1805 SER 1806 -0.2096

SER 1806 THR 1807 0.0004

THR 1807 ALA 1808 -0.4355

ALA 1808 GLU 1809 -0.0004

GLU 1809 ASP 1810 -0.3105

ASP 1810 PHE 1811 -0.0003

PHE 1811 TRP 1812 -0.0526

TRP 1812 ARG 1813 0.0002

ARG 1813 MET 1814 -0.0866

MET 1814 ILE 1815 0.0002

ILE 1815 TRP 1816 0.0854

TRP 1816 GLU 1817 0.0000

GLU 1817 HIS 1818 -0.0840

HIS 1818 ASN 1819 -0.0000

ASN 1819 VAL 1820 -0.0214

VAL 1820 GLU 1821 0.0001

GLU 1821 VAL 1822 -0.0040

VAL 1822 ILE 1823 -0.0000

ILE 1823 VAL 1824 0.0252

VAL 1824 MET 1825 -0.0001

MET 1825 ILE 1826 0.0324

ILE 1826 THR 1827 -0.0001

THR 1827 ASN 1828 -0.0203

ASN 1828 LEU 1829 0.0001

LEU 1829 VAL 1830 -0.0486

VAL 1830 GLU 1831 -0.0003

GLU 1831 LYS 1832 -0.0248

LYS 1832 GLY 1833 -0.0002

GLY 1833 ARG 1834 0.1282

ARG 1834 ARG 1835 0.0000

ARG 1835 LYS 1836 -0.0121

LYS 1836 CYS 1837 0.0000

CYS 1837 ASP 1838 0.0155

ASP 1838 GLN 1839 0.0000

GLN 1839 TYR 1840 0.0937

TYR 1840 TRP 1841 0.0002

TRP 1841 PRO 1842 -0.0397

PRO 1842 ALA 1843 -0.0001

ALA 1843 ASP 1844 -0.0543

ASP 1844 GLY 1845 -0.0003

GLY 1845 SER 1846 -0.0569

SER 1846 GLU 1847 -0.0000

GLU 1847 GLU 1848 -0.0306

GLU 1848 TYR 1849 -0.0003

TYR 1849 GLY 1850 0.0781

GLY 1850 ASN 1851 0.0001

ASN 1851 PHE 1852 0.0221

PHE 1852 LEU 1853 0.0002

LEU 1853 VAL 1854 0.0085

VAL 1854 THR 1855 -0.0000

THR 1855 GLN 1856 0.0144

GLN 1856 LYS 1857 -0.0001

LYS 1857 SER 1858 0.0470

SER 1858 VAL 1859 -0.0001

VAL 1859 GLN 1860 0.0608

GLN 1860 VAL 1861 -0.0000

VAL 1861 LEU 1862 0.0327

LEU 1862 ALA 1863 -0.0003

ALA 1863 TYR 1864 -0.0004

TYR 1864 TYR 1865 -0.0002

TYR 1865 THR 1866 0.0704

THR 1866 VAL 1867 0.0004

VAL 1867 ARG 1868 0.0833

ARG 1868 ASN 1869 0.0002

ASN 1869 PHE 1870 -0.0307

PHE 1870 THR 1871 -0.0005

THR 1871 LEU 1872 -0.1179

LEU 1872 ARG 1873 0.0003

ARG 1873 ASN 1874 0.0602

ASN 1874 THR 1875 0.0003

THR 1875 LYS 1876 -0.1279

LYS 1876 ILE 1877 0.0002

ILE 1877 ARG 1889 0.0866

ARG 1889 VAL 1890 -0.0002

VAL 1890 VAL 1891 0.0194

VAL 1891 THR 1892 -0.0003

THR 1892 GLN 1893 -0.0112

GLN 1893 TYR 1894 -0.0002

TYR 1894 HIS 1895 -0.0945

HIS 1895 TYR 1896 -0.0001

TYR 1896 THR 1897 -0.0811

THR 1897 GLN 1898 0.0001

GLN 1898 TRP 1899 -0.1089

TRP 1899 PRO 1900 0.0001

PRO 1900 ASP 1901 -0.2128

ASP 1901 MET 1902 -0.0002

MET 1902 GLY 1903 0.1753

GLY 1903 VAL 1904 -0.0000

VAL 1904 PRO 1905 -0.0517

PRO 1905 GLU 1906 0.0001

GLU 1906 TYR 1907 -0.0481

TYR 1907 SER 1908 0.0002

SER 1908 LEU 1909 0.0598

LEU 1909 PRO 1910 0.0001

PRO 1910 VAL 1911 0.1461

VAL 1911 LEU 1912 0.0004

LEU 1912 THR 1913 0.1901

THR 1913 PHE 1914 -0.0002

PHE 1914 VAL 1915 -0.0479

VAL 1915 ARG 1916 0.0004

ARG 1916 LYS 1917 0.1675

LYS 1917 ALA 1918 0.0004

ALA 1918 ALA 1919 -0.0464

ALA 1919 TYR 1920 -0.0001

TYR 1920 ALA 1921 0.0325

ALA 1921 LYS 1922 0.0000

LYS 1922 ARG 1923 0.0158

ARG 1923 HIS 1924 -0.0003

HIS 1924 ALA 1925 -0.0485

ALA 1925 VAL 1926 -0.0002

VAL 1926 GLY 1927 -0.0063

GLY 1927 PRO 1928 -0.0000

PRO 1928 VAL 1929 -0.0342

VAL 1929 VAL 1930 -0.0002

VAL 1930 VAL 1931 0.0347

VAL 1931 HIS 1932 -0.0001

HIS 1932 CYS 1933 0.0366

CYS 1933 SER 1934 0.0001

SER 1934 ALA 1935 0.0884

ALA 1935 GLY 1936 -0.0004

GLY 1936 VAL 1937 -0.0454

VAL 1937 GLY 1938 -0.0003

GLY 1938 ARG 1939 0.1793

ARG 1939 THR 1940 0.0004

THR 1940 GLY 1941 -0.0123

GLY 1941 THR 1942 0.0002

THR 1942 TYR 1943 0.1457

TYR 1943 ILE 1944 0.0000

ILE 1944 VAL 1945 -0.0041

VAL 1945 LEU 1946 -0.0002

LEU 1946 ASP 1947 0.0912

ASP 1947 SER 1948 0.0000

SER 1948 MET 1949 -0.0081

MET 1949 LEU 1950 -0.0000

LEU 1950 GLN 1951 -0.0458

GLN 1951 GLN 1952 0.0000

GLN 1952 ILE 1953 0.0599

ILE 1953 GLN 1954 -0.0002

GLN 1954 HIS 1955 -0.0003

HIS 1955 GLU 1956 0.0002

GLU 1956 GLY 1957 0.0190

GLY 1957 THR 1958 -0.0003

THR 1958 VAL 1959 0.0306

VAL 1959 ASN 1960 -0.0001

ASN 1960 ILE 1961 0.0195

ILE 1961 PHE 1962 -0.0002

PHE 1962 GLY 1963 -0.0382

GLY 1963 PHE 1964 -0.0002

PHE 1964 LEU 1965 0.0674

LEU 1965 LYS 1966 -0.0001

LYS 1966 HIS 1967 -0.1717

HIS 1967 ILE 1968 -0.0001

ILE 1968 ARG 1969 0.0575

ARG 1969 SER 1970 -0.0002

SER 1970 GLN 1971 -0.0493

GLN 1971 ARG 1972 -0.0001

ARG 1972 ASN 1973 -0.0044

ASN 1973 TYR 1974 0.0003

TYR 1974 LEU 1975 0.0507

LEU 1975 VAL 1976 -0.0001

VAL 1976 GLN 1977 0.0056

GLN 1977 THR 1978 -0.0001

THR 1978 GLU 1979 -0.0789

GLU 1979 GLU 1980 0.0002

GLU 1980 GLN 1981 0.0181

GLN 1981 TYR 1982 -0.0001

TYR 1982 VAL 1983 -0.0249

VAL 1983 PHE 1984 -0.0002

PHE 1984 ILE 1985 -0.0358

ILE 1985 HIS 1986 0.0002

HIS 1986 ASP 1987 0.0094

ASP 1987 THR 1988 0.0003

THR 1988 LEU 1989 -0.0731

LEU 1989 VAL 1990 0.0001

VAL 1990 GLU 1991 0.1128

GLU 1991 ALA 1992 -0.0000

ALA 1992 ILE 1993 -0.1016

ILE 1993 LEU 1994 -0.0002

LEU 1994 SER 1995 -0.0289

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 8th, 2025.

Should you encounter any unexpected behaviour, please let us know.

*** HYDROLASE/HYDROLASE INHIBITOR 04-OCT-16 5H08 ***

CA strain for 2502261434124124660

--- normal mode 11 ---

Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE/HYDROLASE INHIBITOR 04-OCT-16 5H08 *