Should you encounter any unexpected behaviour,
please let us know.

* *

CA strain for 2406101858502122271

--- normal mode 30 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 GLU 2 0.0001

GLU 2 LEU 3 -0.0002

LEU 3 LYS 4 -0.0002

LYS 4 ASN 5 -0.0001

ASN 5 ILE 6 0.0001

ILE 6 VAL 7 -0.0002

VAL 7 ASN 8 -0.0000

ASN 8 SER 9 0.0003

SER 9 TYR 10 0.0003

TYR 10 ASN 11 -0.0001

ASN 11 ILE 12 -0.0467

ILE 12 THR 13 0.0002

THR 13 ASN 14 0.0003

ASN 14 ILE 15 0.0002

ILE 15 LEU 16 -0.0000

LEU 16 GLY 17 -0.0003

GLY 17 TYR 18 0.0002

TYR 18 LEU 19 0.0000

LEU 19 ARG 20 -0.0002

ARG 20 ARG 21 0.0005

ARG 21 SER 22 -0.0000

SER 22 ARG 23 0.0356

ARG 23 GLN 24 0.0001

GLN 24 ASP 25 -0.0001

ASP 25 MET 26 -0.0001

MET 26 GLU 27 0.0001

GLU 27 ARG 28 -0.0002

ARG 28 GLU 29 0.0001

GLU 29 LYS 30 0.0000

LYS 30 ARG 31 0.0004

ARG 31 THR 32 -0.0001

THR 32 GLY 33 0.0002

GLY 33 GLU 34 0.0067

GLU 34 ASP 35 -0.0002

ASP 35 THR 36 0.0004

THR 36 LEU 37 0.0002

LEU 37 THR 38 0.0002

THR 38 GLU 39 -0.0001

GLU 39 GLN 40 -0.0001

GLN 40 LYS 41 -0.0003

LYS 41 GLU 42 -0.0001

GLU 42 LEU 43 -0.0003

LEU 43 MET 44 0.0001

MET 44 ASN 45 0.0057

ASN 45 LYS 46 -0.0005

LYS 46 ILE 47 -0.0001

ILE 47 LEU 48 0.0004

LEU 48 THR 49 0.0003

THR 49 ALA 50 -0.0002

ALA 50 ILE 51 0.0000

ILE 51 GLU 52 -0.0000

GLU 52 ILE 53 0.0000

ILE 53 PRO 54 0.0003

PRO 54 TYR 55 0.0001

TYR 55 GLU 56 0.0045

GLU 56 LEU 57 -0.0004

LEU 57 LYS 58 0.0003

LYS 58 MET 59 -0.0003

MET 59 GLU 60 0.0000

GLU 60 ILE 61 -0.0002

ILE 61 GLY 62 -0.0000

GLY 62 SER 63 -0.0001

SER 63 GLY 64 -0.0001

GLY 64 GLU 65 -0.0000

GLU 65 SER 66 0.0003

SER 66 ILE 67 0.0185

ILE 67 ASP 68 0.0002

ASP 68 GLY 69 0.0000

GLY 69 ARG 70 0.0002

ARG 70 PRO 71 0.0000

PRO 71 VAL 72 0.0002

VAL 72 PHE 73 -0.0000

PHE 73 LYS 74 0.0001

LYS 74 GLU 75 0.0002

GLU 75 CYS 76 0.0004

CYS 76 LEU 77 -0.0004

LEU 77 LYS 78 0.0067

LYS 78 ASP 79 -0.0003

ASP 79 LEU 80 0.0003

LEU 80 GLU 81 -0.0001

GLU 81 GLU 82 -0.0002

GLU 82 GLY 83 -0.0003

GLY 83 LYS 84 -0.0000

LYS 84 TYR 85 0.0001

TYR 85 GLN 86 0.0002

GLN 86 ALA 87 -0.0004

ALA 87 ILE 88 0.0004

ILE 88 ALA 89 -0.0036

ALA 89 VAL 90 0.0000

VAL 90 LYS 91 -0.0003

LYS 91 GLU 92 -0.0000

GLU 92 ILE 93 -0.0000

ILE 93 THR 94 0.0003

THR 94 ARG 95 0.0001

ARG 95 LEU 96 0.0003

LEU 96 SER 97 0.0000

SER 97 ARG 98 -0.0001

ARG 98 GLY 99 0.0005

GLY 99 SER 100 0.0052

SER 100 TYR 101 -0.0001

TYR 101 SER 102 0.0004

SER 102 ASP 103 0.0000

ASP 103 ALA 104 -0.0000

ALA 104 GLY 105 0.0000

GLY 105 GLN 106 -0.0002

GLN 106 ILE 107 -0.0004

ILE 107 VAL 108 -0.0001

VAL 108 ASN 109 0.0001

ASN 109 LEU 110 0.0002

LEU 110 LEU 111 0.0045

LEU 111 GLN 112 0.0001

GLN 112 SER 113 0.0004

SER 113 LYS 114 -0.0001

LYS 114 ARG 115 0.0003

ARG 115 LEU 116 0.0002

LEU 116 ILE 117 -0.0002

ILE 117 ILE 118 -0.0000

ILE 118 ILE 119 0.0000

ILE 119 THR 120 0.0000

THR 120 PRO 121 -0.0001

PRO 121 TYR 122 0.0193

TYR 122 LYS 123 0.0001

LYS 123 VAL 124 0.0002

VAL 124 TYR 125 0.0000

TYR 125 ASP 126 -0.0003

ASP 126 PRO 127 0.0003

PRO 127 ARG 128 0.0004

ARG 128 ASN 129 0.0001

ASN 129 PRO 130 -0.0002

PRO 130 VAL 131 0.0000

VAL 131 ASP 132 -0.0002

ASP 132 MET 133 0.0183

MET 133 ARG 134 0.0002

ARG 134 GLN 135 -0.0002

GLN 135 ILE 136 -0.0001

ILE 136 ARG 137 -0.0001

ARG 137 PHE 138 0.0000

PHE 138 GLU 139 0.0002

GLU 139 LEU 140 0.0002

LEU 140 PHE 141 -0.0001

PHE 141 MET 142 0.0001

MET 142 ALA 143 0.0002

ALA 143 ARG 144 -0.0133

ARG 144 GLU 145 0.0001

GLU 145 GLU 146 0.0000

GLU 146 PHE 147 0.0001

PHE 147 GLU 148 0.0000

GLU 148 MET 149 0.0001

MET 149 THR 150 0.0003

THR 150 ARG 151 0.0003

ARG 151 GLU 152 -0.0000

GLU 152 ARG 153 0.0003

ARG 153 MET 154 0.0003

MET 154 THR 155 -0.0898

THR 155 GLY 156 0.0003

GLY 156 ALA 157 -0.0003

ALA 157 LYS 158 -0.0001

LYS 158 TYR 159 -0.0001

TYR 159 THR 160 0.0002

THR 160 TYR 161 -0.0002

TYR 161 ALA 162 -0.0002

ALA 162 ALA 163 0.0000

ALA 163 GLN 164 -0.0003

GLN 164 GLY 165 0.0004

GLY 165 LYS 166 -0.0502

LYS 166 TRP 167 -0.0005

TRP 167 ILE 168 -0.0000

ILE 168 SER 169 -0.0003

SER 169 GLY 170 -0.0003

GLY 170 LEU 171 0.0003

LEU 171 ALA 172 0.0000

ALA 172 PRO 173 -0.0005

PRO 173 TYR 174 0.0002

TYR 174 GLY 175 0.0002

GLY 175 TYR 176 0.0000

TYR 176 GLN 177 -0.0343

GLN 177 LEU 178 0.0002

LEU 178 ASN 179 -0.0004

ASN 179 LYS 180 0.0000

LYS 180 LYS 181 -0.0003

LYS 181 THR 182 0.0002

THR 182 SER 183 -0.0001

SER 183 LYS 184 0.0001

LYS 184 LEU 185 -0.0002

LEU 185 ASP 186 -0.0000

ASP 186 PRO 187 0.0002

PRO 187 VAL 188 -0.0298

VAL 188 GLU 189 0.0001

GLU 189 ASP 190 -0.0001

ASP 190 GLU 191 0.0002

GLU 191 ALA 192 -0.0000

ALA 192 LYS 193 0.0001

LYS 193 VAL 194 0.0003

VAL 194 VAL 195 -0.0001

VAL 195 GLN 196 -0.0002

GLN 196 LEU 197 0.0004

LEU 197 ILE 198 -0.0002

ILE 198 PHE 199 -0.0029

PHE 199 ASN 200 -0.0002

ASN 200 ILE 201 0.0001

ILE 201 PHE 202 -0.0001

PHE 202 LEU 203 0.0000

LEU 203 ASN 204 -0.0004

ASN 204 GLY 205 -0.0003

GLY 205 LEU 206 0.0002

LEU 206 ASN 207 -0.0001

ASN 207 GLY 208 -0.0004

GLY 208 LYS 209 0.0001

LYS 209 ASP 210 0.0059

ASP 210 TYR 211 0.0000

TYR 211 SER 212 -0.0003

SER 212 TYR 213 0.0003

TYR 213 THR 214 0.0003

THR 214 ALA 215 0.0002

ALA 215 ILE 216 0.0002

ILE 216 ALA 217 -0.0001

ALA 217 SER 218 0.0004

SER 218 HIS 219 -0.0000

HIS 219 LEU 220 -0.0001

LEU 220 THR 221 -0.0069

THR 221 ASN 222 -0.0001

ASN 222 LEU 223 -0.0002

LEU 223 GLN 224 -0.0002

GLN 224 ILE 225 -0.0001

ILE 225 PRO 226 -0.0002

PRO 226 THR 227 -0.0000

THR 227 PRO 228 0.0001

PRO 228 SER 229 0.0002

SER 229 GLY 230 -0.0001

GLY 230 LYS 231 0.0001

LYS 231 LYS 232 -0.0254

LYS 232 ARG 233 0.0004

ARG 233 TRP 234 -0.0003

TRP 234 ASN 235 -0.0000

ASN 235 GLN 236 0.0000

GLN 236 TYR 237 0.0002

TYR 237 THR 238 -0.0001

THR 238 ILE 239 -0.0000

ILE 239 LYS 240 0.0003

LYS 240 ALA 241 0.0000

ALA 241 ILE 242 0.0000

ILE 242 LEU 243 0.0146

LEU 243 GLN 244 0.0000

GLN 244 ASN 245 -0.0003

ASN 245 GLU 246 -0.0000

GLU 246 VAL 247 -0.0000

VAL 247 TYR 248 -0.0000

TYR 248 ILE 249 -0.0004

ILE 249 GLY 250 0.0004

GLY 250 THR 251 0.0001

THR 251 VAL 252 0.0001

VAL 252 LYS 253 0.0002

LYS 253 TYR 254 -0.0504

TYR 254 LYS 255 -0.0002

LYS 255 VAL 256 -0.0001

VAL 256 ARG 257 -0.0004

ARG 257 GLU 258 0.0005

GLU 258 LYS 259 -0.0000

LYS 259 THR 260 -0.0000

THR 260 LYS 261 0.0002

LYS 261 ASP 262 0.0004

ASP 262 GLY 263 -0.0003

GLY 263 LYS 264 0.0001

LYS 264 ARG 265 0.0140

ARG 265 THR 266 0.0002

THR 266 ILE 267 0.0000

ILE 267 ARG 268 0.0002

ARG 268 PRO 269 -0.0000

PRO 269 GLU 270 0.0001

GLU 270 LYS 271 -0.0000

LYS 271 GLU 272 0.0000

GLU 272 GLN 273 -0.0003

GLN 273 ILE 274 0.0001

ILE 274 VAL 275 0.0000

VAL 275 VAL 276 -0.0676

VAL 276 GLN 277 -0.0004

GLN 277 ASP 278 0.0001

ASP 278 ALA 279 0.0001

ALA 279 HIS 280 -0.0000

HIS 280 ALA 281 0.0000

ALA 281 PRO 282 0.0002

PRO 282 ILE 283 0.0005

ILE 283 ILE 284 0.0002

ILE 284 ASP 285 0.0000

ASP 285 LYS 286 -0.0001

LYS 286 GLU 287 -0.0294

GLU 287 GLN 288 0.0002

GLN 288 PHE 289 -0.0003

PHE 289 GLN 290 0.0001

GLN 290 GLN 291 0.0004

GLN 291 SER 292 -0.0002

SER 292 GLN 293 -0.0004

GLN 293 VAL 294 0.0004

VAL 294 LYS 295 -0.0004

LYS 295 ILE 296 -0.0001

ILE 296 ALA 297 0.0000

ALA 297 ASN 298 0.0380

ASN 298 LYS 299 -0.0002

LYS 299 VAL 300 0.0001

VAL 300 PRO 301 0.0001

PRO 301 LEU 302 0.0001

LEU 302 LEU 303 0.0002

LEU 303 PRO 304 0.0002

PRO 304 ASN 305 -0.0002

ASN 305 LYS 306 0.0000

LYS 306 ASP 307 -0.0002

ASP 307 GLU 308 0.0003

GLU 308 PHE 309 0.0043

PHE 309 GLU 310 0.0003

GLU 310 LEU 311 0.0002

LEU 311 SER 312 -0.0002

SER 312 GLU 313 0.0001

GLU 313 LEU 314 -0.0001

LEU 314 ALA 315 -0.0001

ALA 315 GLY 316 0.0000

GLY 316 VAL 317 -0.0000

VAL 317 CYS 318 -0.0002

CYS 318 THR 319 -0.0000

THR 319 CYS 320 0.0938

CYS 320 SER 321 -0.0000

SER 321 LYS 322 0.0003

LYS 322 CYS 323 -0.0004

CYS 323 GLY 324 0.0000

GLY 324 GLU 325 0.0002

GLU 325 PRO 326 0.0003

PRO 326 LEU 327 0.0002

LEU 327 SER 328 0.0002

SER 328 LYS 329 -0.0000

LYS 329 TYR 330 0.0002

TYR 330 GLU 331 -0.0557

GLU 331 SER 332 0.0001

SER 332 LYS 333 -0.0001

LYS 333 ARG 334 0.0004

ARG 334 ILE 335 -0.0002

ILE 335 ARG 336 -0.0002

ARG 336 LYS 337 -0.0003

LYS 337 ASN 338 0.0000

ASN 338 LYS 339 0.0002

LYS 339 ASP 340 0.0000

ASP 340 GLY 341 0.0003

GLY 341 THR 342 -0.0079

THR 342 GLU 343 -0.0000

GLU 343 SER 344 -0.0000

SER 344 VAL 345 0.0002

VAL 345 TYR 346 -0.0003

TYR 346 HIS 347 0.0005

HIS 347 VAL 348 -0.0001

VAL 348 LYS 349 -0.0002

LYS 349 SER 350 0.0001

SER 350 LEU 351 -0.0001

LEU 351 THR 352 0.0001

THR 352 CYS 353 0.0407

CYS 353 LYS 354 -0.0001

LYS 354 LYS 355 0.0004

LYS 355 ASN 356 -0.0002

ASN 356 LYS 357 0.0001

LYS 357 CYS 358 -0.0000

CYS 358 THR 359 -0.0003

THR 359 TYR 360 0.0002

TYR 360 VAL 361 0.0001

VAL 361 ARG 362 -0.0000

ARG 362 TYR 363 -0.0003

TYR 363 ASN 364 0.0060

ASN 364 ASP 365 -0.0000

ASP 365 VAL 366 0.0003

VAL 366 GLU 367 0.0000

GLU 367 ASN 368 -0.0002

ASN 368 ALA 369 -0.0002

ALA 369 ILE 370 -0.0003

ILE 370 LEU 371 -0.0003

LEU 371 ASP 372 0.0001

ASP 372 TYR 373 -0.0001

TYR 373 LEU 374 0.0003

LEU 374 SER 375 0.0080

SER 375 SER 376 -0.0002

SER 376 LEU 377 -0.0000

LEU 377 ASN 378 0.0003

ASN 378 ASP 379 0.0001

ASP 379 LEU 380 -0.0001

LEU 380 ASN 381 -0.0000

ASN 381 ASP 382 0.0001

ASP 382 SER 383 0.0001

SER 383 THR 384 -0.0002

THR 384 LEU 385 0.0002

LEU 385 THR 386 0.0238

THR 386 LYS 387 -0.0002

LYS 387 HIS 388 0.0001

HIS 388 ILE 389 0.0003

ILE 389 ASN 390 0.0000

ASN 390 SER 391 0.0002

SER 391 MET 392 -0.0000

MET 392 LEU 393 -0.0000

LEU 393 SER 394 0.0001

SER 394 LYS 395 -0.0000

LYS 395 TYR 396 0.0000

TYR 396 GLU 397 0.0421

GLU 397 ASP 398 0.0002

ASP 398 ASP 399 0.0001

ASP 399 ASN 400 0.0000

ASN 400 SER 401 -0.0000

SER 401 ASN 402 -0.0003

ASN 402 MET 403 0.0001

MET 403 LYS 404 -0.0005

LYS 404 THR 405 -0.0001

THR 405 LYS 406 -0.0004

LYS 406 LYS 407 -0.0000

LYS 407 GLN 408 -0.0436

GLN 408 MET 409 -0.0003

MET 409 SER 410 0.0001

SER 410 GLU 411 0.0003

GLU 411 HIS 412 0.0000

HIS 412 LEU 413 -0.0001

LEU 413 SER 414 0.0000

SER 414 GLN 415 -0.0003

GLN 415 LYS 416 0.0000

LYS 416 GLU 417 -0.0002

GLU 417 LYS 418 -0.0000

LYS 418 GLU 419 -0.0428

GLU 419 LEU 420 0.0002

LEU 420 LYS 421 -0.0002

LYS 421 ASN 422 0.0002

ASN 422 LYS 423 0.0006

LYS 423 GLU 424 0.0001

GLU 424 ASN 425 0.0003

ASN 425 PHE 426 0.0003

PHE 426 ILE 427 0.0001

ILE 427 PHE 428 0.0000

PHE 428 ASP 429 -0.0000

ASP 429 LYS 430 0.0068

LYS 430 TYR 431 -0.0000

TYR 431 GLU 432 0.0003

GLU 432 SER 433 0.0001

SER 433 GLY 434 0.0001

GLY 434 ILE 435 0.0004

ILE 435 TYR 436 0.0000

TYR 436 SER 437 -0.0004

SER 437 ASP 438 -0.0001

ASP 438 GLU 439 -0.0000

GLU 439 LEU 440 0.0000

LEU 440 PHE 441 0.0095

PHE 441 LEU 442 -0.0001

LEU 442 LYS 443 -0.0004

LYS 443 ARG 444 0.0002

ARG 444 LYS 445 -0.0001

LYS 445 ALA 446 -0.0003

ALA 446 ALA 447 0.0001

ALA 447 LEU 448 0.0001

LEU 448 ASP 449 -0.0004

ASP 449 GLU 450 0.0001

GLU 450 GLU 451 0.0002

GLU 451 PHE 452 -0.0274

PHE 452 LYS 453 0.0001

LYS 453 GLU 454 -0.0003

GLU 454 LEU 455 0.0002

LEU 455 GLN 456 -0.0000

GLN 456 ASN 457 0.0001

ASN 457 ALA 458 -0.0002

ALA 458 LYS 459 -0.0000

LYS 459 ASN 460 -0.0000

ASN 460 GLU 461 -0.0003

GLU 461 LEU 462 -0.0001

LEU 462 ASN 463 -0.0319

ASN 463 GLY 464 -0.0002

GLY 464 LEU 465 -0.0002

LEU 465 GLN 466 -0.0001

GLN 466 ASP 467 0.0002

ASP 467 THR 468 0.0001

THR 468 GLN 469 0.0003

GLN 469 SER 470 0.0000

SER 470 GLU 471 0.0002

GLU 471 ILE 472 -0.0003

ILE 472 ASP 473 0.0001

ASP 473 SER 474 -0.0459

SER 474 ASN 475 0.0001

ASN 475 THR 476 -0.0005

THR 476 VAL 477 0.0002

VAL 477 ARG 478 -0.0000

ARG 478 ASN 479 0.0003

ASN 479 ASN 480 -0.0004

ASN 480 ILE 481 0.0004

ILE 481 ASN 482 -0.0003

ASN 482 LYS 483 -0.0000

LYS 483 ILE 484 0.0003

ILE 484 ILE 485 -0.0208

ILE 485 ASP 486 0.0001

ASP 486 GLN 487 -0.0006

GLN 487 TYR 488 0.0004

TYR 488 HIS 489 -0.0002

HIS 489 ILE 490 0.0002

ILE 490 GLU 491 -0.0000

GLU 491 SER 492 0.0002

SER 492 SER 493 -0.0000

SER 493 SER 494 0.0004

SER 494 GLU 495 0.0001

GLU 495 LYS 496 0.0019

LYS 496 LYS 497 0.0001

LYS 497 ASN 498 0.0001

ASN 498 GLU 499 0.0000

GLU 499 LEU 500 0.0000

LEU 500 LEU 501 0.0002

LEU 501 ARG 502 0.0001

ARG 502 MET 503 -0.0002

MET 503 VAL 504 0.0001

VAL 504 LEU 505 0.0004

LEU 505 LYS 506 -0.0000

LYS 506 ASP 507 0.0866

ASP 507 VAL 508 0.0001

VAL 508 ILE 509 0.0003

ILE 509 VAL 510 0.0001

VAL 510 ASN 511 -0.0002

ASN 511 MET 512 -0.0005

MET 512 THR 513 -0.0000

THR 513 GLN 514 -0.0001

GLN 514 LYS 515 0.0004

LYS 515 ARG 516 0.0000

ARG 516 LYS 517 0.0000

LYS 517 GLY 518 0.0068

GLY 518 PRO 519 0.0002

PRO 519 ILE 520 0.0000

ILE 520 PRO 521 -0.0001

PRO 521 ALA 522 0.0002

ALA 522 GLN 523 0.0002

GLN 523 PHE 524 -0.0002

PHE 524 GLU 525 -0.0000

GLU 525 ILE 526 0.0002

ILE 526 THR 527 -0.0002

THR 527 PRO 528 -0.0000

PRO 528 ILE 529 0.0265

ILE 529 LEU 530 -0.0000

LEU 530 ARG 531 0.0002

ARG 531 PHE 532 -0.0000

PHE 532 ASN 533 0.0001

ASN 533 PHE 534 0.0003

PHE 534 ILE 535 -0.0000

ILE 535 PHE 536 0.0001

PHE 536 ASP 537 -0.0003

ASP 537 LEU 538 0.0001

LEU 538 THR 539 0.0002

THR 539 ALA 540 -0.0336

ALA 540 THR 541 0.0001

THR 541 ASN 542 -0.0000

ASN 542 SER 543 -0.0004

SER 543 PHE 544 -0.0000

PHE 544 HIS 545 -0.0002

HIS 545 MET 1 -0.0595

MET 1 GLU 2 0.0002

GLU 2 LEU 3 -0.0000

LEU 3 LYS 4 -0.0000

LYS 4 ASN 5 0.0002

ASN 5 ILE 6 -0.0001

ILE 6 VAL 7 -0.0000

VAL 7 ASN 8 -0.0002

ASN 8 SER 9 -0.0002

SER 9 TYR 10 -0.0000

TYR 10 ASN 11 0.0000

ASN 11 ILE 12 0.0221

ILE 12 THR 13 0.0003

THR 13 ASN 14 0.0003

ASN 14 ILE 15 -0.0001

ILE 15 LEU 16 -0.0001

LEU 16 GLY 17 0.0003

GLY 17 TYR 18 -0.0002

TYR 18 LEU 19 0.0002

LEU 19 ARG 20 -0.0000

ARG 20 ARG 21 -0.0003

ARG 21 SER 22 0.0003

SER 22 ARG 23 0.0512

ARG 23 GLN 24 -0.0002

GLN 24 ASP 25 -0.0001

ASP 25 MET 26 -0.0001

MET 26 GLU 27 0.0001

GLU 27 ARG 28 0.0001

ARG 28 GLU 29 -0.0000

GLU 29 LYS 30 0.0001

LYS 30 ARG 31 0.0000

ARG 31 THR 32 0.0001

THR 32 GLY 33 0.0003

GLY 33 GLU 34 0.0405

GLU 34 ASP 35 0.0001

ASP 35 THR 36 -0.0000

THR 36 LEU 37 -0.0001

LEU 37 THR 38 -0.0001

THR 38 GLU 39 0.0000

GLU 39 GLN 40 0.0001

GLN 40 LYS 41 0.0003

LYS 41 GLU 42 -0.0004

GLU 42 LEU 43 0.0003

LEU 43 MET 44 0.0000

MET 44 ASN 45 0.0119

ASN 45 LYS 46 -0.0000

LYS 46 ILE 47 0.0001

ILE 47 LEU 48 0.0003

LEU 48 THR 49 0.0001

THR 49 ALA 50 -0.0001

ALA 50 ILE 51 -0.0001

ILE 51 GLU 52 0.0001

GLU 52 ILE 53 -0.0002

ILE 53 PRO 54 0.0002

PRO 54 TYR 55 0.0003

TYR 55 GLU 56 0.0170

GLU 56 LEU 57 -0.0003

LEU 57 LYS 58 -0.0003

LYS 58 MET 59 -0.0000

MET 59 GLU 60 -0.0001

GLU 60 ILE 61 -0.0001

ILE 61 GLY 62 -0.0001

GLY 62 SER 63 0.0004

SER 63 GLY 64 -0.0001

GLY 64 GLU 65 -0.0000

GLU 65 SER 66 -0.0001

SER 66 ILE 67 0.0556

ILE 67 ASP 68 -0.0002

ASP 68 GLY 69 -0.0002

GLY 69 ARG 70 -0.0002

ARG 70 PRO 71 -0.0000

PRO 71 VAL 72 0.0001

VAL 72 PHE 73 -0.0001

PHE 73 LYS 74 -0.0001

LYS 74 GLU 75 0.0002

GLU 75 CYS 76 0.0003

CYS 76 LEU 77 0.0002

LEU 77 LYS 78 0.0183

LYS 78 ASP 79 0.0001

ASP 79 LEU 80 -0.0004

LEU 80 GLU 81 0.0000

GLU 81 GLU 82 0.0002

GLU 82 GLY 83 0.0001

GLY 83 LYS 84 0.0003

LYS 84 TYR 85 0.0004

TYR 85 GLN 86 -0.0003

GLN 86 ALA 87 -0.0004

ALA 87 ILE 88 0.0001

ILE 88 ALA 89 0.0026

ALA 89 VAL 90 0.0001

VAL 90 LYS 91 -0.0003

LYS 91 GLU 92 0.0002

GLU 92 ILE 93 -0.0001

ILE 93 THR 94 -0.0002

THR 94 ARG 95 -0.0001

ARG 95 LEU 96 0.0000

LEU 96 SER 97 0.0003

SER 97 ARG 98 -0.0003

ARG 98 GLY 99 0.0001

GLY 99 SER 100 0.0022

SER 100 TYR 101 -0.0001

TYR 101 SER 102 0.0002

SER 102 ASP 103 -0.0002

ASP 103 ALA 104 0.0002

ALA 104 GLY 105 -0.0003

GLY 105 GLN 106 -0.0004

GLN 106 ILE 107 -0.0002

ILE 107 VAL 108 -0.0001

VAL 108 ASN 109 0.0003

ASN 109 LEU 110 0.0002

LEU 110 LEU 111 -0.0090

LEU 111 GLN 112 0.0003

GLN 112 SER 113 -0.0001

SER 113 LYS 114 0.0003

LYS 114 ARG 115 -0.0002

ARG 115 LEU 116 0.0004

LEU 116 ILE 117 -0.0004

ILE 117 ILE 118 0.0001

ILE 118 ILE 119 0.0003

ILE 119 THR 120 0.0002

THR 120 PRO 121 -0.0005

PRO 121 TYR 122 0.0228

TYR 122 LYS 123 -0.0002

LYS 123 VAL 124 -0.0001

VAL 124 TYR 125 -0.0001

TYR 125 ASP 126 0.0001

ASP 126 PRO 127 -0.0002

PRO 127 ARG 128 0.0001

ARG 128 ASN 129 -0.0002

ASN 129 PRO 130 -0.0003

PRO 130 VAL 131 -0.0001

VAL 131 ASP 132 0.0001

ASP 132 MET 133 -0.0090

MET 133 ARG 134 -0.0002

ARG 134 GLN 135 -0.0002

GLN 135 ILE 136 -0.0002

ILE 136 ARG 137 0.0000

ARG 137 PHE 138 0.0002

PHE 138 GLU 139 -0.0002

GLU 139 LEU 140 0.0001

LEU 140 PHE 141 0.0002

PHE 141 MET 142 -0.0001

MET 142 ALA 143 0.0002

ALA 143 ARG 144 -0.0114

ARG 144 GLU 145 0.0000

GLU 145 GLU 146 0.0004

GLU 146 PHE 147 0.0003

PHE 147 GLU 148 0.0001

GLU 148 MET 149 0.0001

MET 149 THR 150 0.0003

THR 150 ARG 151 -0.0001

ARG 151 GLU 152 0.0002

GLU 152 ARG 153 -0.0003

ARG 153 MET 154 0.0002

MET 154 THR 155 -0.0473

THR 155 GLY 156 0.0000

GLY 156 ALA 157 -0.0001

ALA 157 LYS 158 0.0001

LYS 158 TYR 159 0.0001

TYR 159 THR 160 -0.0001

THR 160 TYR 161 -0.0002

TYR 161 ALA 162 -0.0001

ALA 162 ALA 163 -0.0001

ALA 163 GLN 164 0.0004

GLN 164 GLY 165 0.0001

GLY 165 LYS 166 -0.0104

LYS 166 TRP 167 -0.0001

TRP 167 ILE 168 -0.0002

ILE 168 SER 169 0.0002

SER 169 GLY 170 -0.0001

GLY 170 LEU 171 -0.0003

LEU 171 ALA 172 0.0001

ALA 172 PRO 173 -0.0002

PRO 173 TYR 174 0.0000

TYR 174 GLY 175 -0.0002

GLY 175 TYR 176 0.0001

TYR 176 GLN 177 0.0077

GLN 177 LEU 178 -0.0002

LEU 178 ASN 179 0.0002

ASN 179 LYS 180 -0.0001

LYS 180 LYS 181 0.0002

LYS 181 THR 182 -0.0001

THR 182 SER 183 -0.0002

SER 183 LYS 184 0.0001

LYS 184 LEU 185 -0.0002

LEU 185 ASP 186 0.0001

ASP 186 PRO 187 0.0002

PRO 187 VAL 188 0.0113

VAL 188 GLU 189 0.0002

GLU 189 ASP 190 -0.0000

ASP 190 GLU 191 0.0002

GLU 191 ALA 192 -0.0002

ALA 192 LYS 193 0.0000

LYS 193 VAL 194 0.0002

VAL 194 VAL 195 0.0001

VAL 195 GLN 196 0.0000

GLN 196 LEU 197 -0.0002

LEU 197 ILE 198 0.0003

ILE 198 PHE 199 0.0069

PHE 199 ASN 200 -0.0002

ASN 200 ILE 201 -0.0001

ILE 201 PHE 202 -0.0001

PHE 202 LEU 203 -0.0003

LEU 203 ASN 204 -0.0001

ASN 204 GLY 205 -0.0000

GLY 205 LEU 206 0.0003

LEU 206 ASN 207 0.0003

ASN 207 GLY 208 0.0001

GLY 208 LYS 209 0.0001

LYS 209 ASP 210 -0.0225

ASP 210 TYR 211 0.0000

TYR 211 SER 212 -0.0001

SER 212 TYR 213 0.0001

TYR 213 THR 214 -0.0004

THR 214 ALA 215 0.0000

ALA 215 ILE 216 0.0001

ILE 216 ALA 217 0.0001

ALA 217 SER 218 0.0002

SER 218 HIS 219 0.0001

HIS 219 LEU 220 0.0001

LEU 220 THR 221 -0.0075

THR 221 ASN 222 0.0000

ASN 222 LEU 223 -0.0002

LEU 223 GLN 224 0.0001

GLN 224 ILE 225 0.0000

ILE 225 PRO 226 0.0002

PRO 226 THR 227 0.0001

THR 227 PRO 228 -0.0002

PRO 228 SER 229 0.0001

SER 229 GLY 230 0.0003

GLY 230 LYS 231 0.0000

LYS 231 LYS 232 -0.0061

LYS 232 ARG 233 -0.0002

ARG 233 TRP 234 -0.0000

TRP 234 ASN 235 -0.0004

ASN 235 GLN 236 -0.0000

GLN 236 TYR 237 -0.0003

TYR 237 THR 238 -0.0001

THR 238 ILE 239 -0.0001

ILE 239 LYS 240 0.0002

LYS 240 ALA 241 -0.0002

ALA 241 ILE 242 0.0001

ILE 242 LEU 243 0.0331

LEU 243 GLN 244 0.0001

GLN 244 ASN 245 0.0002

ASN 245 GLU 246 0.0001

GLU 246 VAL 247 -0.0000

VAL 247 TYR 248 0.0001

TYR 248 ILE 249 0.0003

ILE 249 GLY 250 0.0001

GLY 250 THR 251 -0.0001

THR 251 VAL 252 -0.0004

VAL 252 LYS 253 -0.0000

LYS 253 TYR 254 -0.2122

TYR 254 LYS 255 -0.0001

LYS 255 VAL 256 0.0003

VAL 256 ARG 257 -0.0000

ARG 257 GLU 258 0.0003

GLU 258 LYS 259 -0.0003

LYS 259 THR 260 0.0003

THR 260 LYS 261 0.0000

LYS 261 ASP 262 -0.0001

ASP 262 GLY 263 -0.0001

GLY 263 LYS 264 -0.0001

LYS 264 ARG 265 0.0192

ARG 265 THR 266 -0.0001

THR 266 ILE 267 -0.0000

ILE 267 ARG 268 -0.0003

ARG 268 PRO 269 -0.0001

PRO 269 GLU 270 -0.0001

GLU 270 LYS 271 0.0003

LYS 271 GLU 272 -0.0001

GLU 272 GLN 273 -0.0000

GLN 273 ILE 274 0.0003

ILE 274 VAL 275 0.0001

VAL 275 VAL 276 -0.0939

VAL 276 GLN 277 0.0004

GLN 277 ASP 278 -0.0002

ASP 278 ALA 279 0.0002

ALA 279 HIS 280 0.0002

HIS 280 ALA 281 0.0001

ALA 281 PRO 282 -0.0003

PRO 282 ILE 283 0.0001

ILE 283 ILE 284 -0.0001

ILE 284 ASP 285 0.0001

ASP 285 LYS 286 -0.0002

LYS 286 GLU 287 -0.0074

GLU 287 GLN 288 0.0001

GLN 288 PHE 289 0.0001

PHE 289 GLN 290 -0.0001

GLN 290 GLN 291 0.0004

GLN 291 SER 292 0.0000

SER 292 GLN 293 0.0002

GLN 293 VAL 294 -0.0004

VAL 294 LYS 295 -0.0002

LYS 295 ILE 296 0.0002

ILE 296 ALA 297 0.0001

ALA 297 ASN 298 0.0694

ASN 298 LYS 299 0.0001

LYS 299 VAL 300 -0.0000

VAL 300 PRO 301 -0.0002

PRO 301 LEU 302 -0.0004

LEU 302 LEU 303 0.0001

LEU 303 PRO 304 -0.0002

PRO 304 ASN 305 -0.0000

ASN 305 LYS 306 0.0000

LYS 306 ASP 307 -0.0001

ASP 307 GLU 308 0.0002

GLU 308 PHE 309 0.1649

PHE 309 GLU 310 0.0000

GLU 310 LEU 311 -0.0001

LEU 311 SER 312 0.0001

SER 312 GLU 313 -0.0004

GLU 313 LEU 314 0.0002

LEU 314 ALA 315 0.0002

ALA 315 GLY 316 0.0002

GLY 316 VAL 317 0.0002

VAL 317 CYS 318 0.0002

CYS 318 THR 319 0.0001

THR 319 CYS 320 -0.1019

CYS 320 SER 321 0.0004

SER 321 LYS 322 -0.0000

LYS 322 CYS 323 -0.0004

CYS 323 GLY 324 0.0001

GLY 324 GLU 325 -0.0003

GLU 325 PRO 326 0.0000

PRO 326 LEU 327 -0.0000

LEU 327 SER 328 -0.0001

SER 328 LYS 329 0.0001

LYS 329 TYR 330 -0.0001

TYR 330 GLU 331 0.0155

GLU 331 SER 332 -0.0002

SER 332 LYS 333 0.0000

LYS 333 ARG 334 0.0002

ARG 334 ILE 335 0.0000

ILE 335 ARG 336 -0.0002

ARG 336 LYS 337 0.0002

LYS 337 ASN 338 -0.0002

ASN 338 LYS 339 0.0002

LYS 339 ASP 340 0.0001

ASP 340 GLY 341 -0.0004

GLY 341 THR 342 0.0613

THR 342 GLU 343 -0.0000

GLU 343 SER 344 0.0003

SER 344 VAL 345 -0.0000

VAL 345 TYR 346 -0.0002

TYR 346 HIS 347 0.0002

HIS 347 VAL 348 -0.0000

VAL 348 LYS 349 -0.0001

LYS 349 SER 350 -0.0003

SER 350 LEU 351 0.0002

LEU 351 THR 352 -0.0001

THR 352 CYS 353 -0.1176

CYS 353 LYS 354 0.0001

LYS 354 LYS 355 -0.0001

LYS 355 ASN 356 0.0001

ASN 356 LYS 357 -0.0002

LYS 357 CYS 358 0.0001

CYS 358 THR 359 0.0001

THR 359 TYR 360 0.0004

TYR 360 VAL 361 0.0002

VAL 361 ARG 362 -0.0002

ARG 362 TYR 363 0.0003

TYR 363 ASN 364 0.0560

ASN 364 ASP 365 0.0002

ASP 365 VAL 366 -0.0002

VAL 366 GLU 367 0.0001

GLU 367 ASN 368 -0.0000

ASN 368 ALA 369 0.0002

ALA 369 ILE 370 -0.0004

ILE 370 LEU 371 -0.0001

LEU 371 ASP 372 -0.0001

ASP 372 TYR 373 -0.0001

TYR 373 LEU 374 -0.0001

LEU 374 SER 375 -0.0521

SER 375 SER 376 0.0004

SER 376 LEU 377 0.0001

LEU 377 ASN 378 0.0000

ASN 378 ASP 379 -0.0002

ASP 379 LEU 380 -0.0000

LEU 380 ASN 381 0.0003

ASN 381 ASP 382 0.0001

ASP 382 SER 383 -0.0001

SER 383 THR 384 0.0001

THR 384 LEU 385 0.0004

LEU 385 THR 386 0.0088

THR 386 LYS 387 0.0002

LYS 387 HIS 388 -0.0001

HIS 388 ILE 389 -0.0002

ILE 389 ASN 390 -0.0005

ASN 390 SER 391 0.0001

SER 391 MET 392 0.0000

MET 392 LEU 393 0.0001

LEU 393 SER 394 -0.0002

SER 394 LYS 395 0.0004

LYS 395 TYR 396 -0.0002

TYR 396 GLU 397 -0.1945

GLU 397 ASP 398 0.0001

ASP 398 ASP 399 0.0002

ASP 399 ASN 400 0.0002

ASN 400 SER 401 -0.0002

SER 401 ASN 402 -0.0002

ASN 402 MET 403 0.0000

MET 403 LYS 404 -0.0002

LYS 404 THR 405 0.0004

THR 405 LYS 406 0.0000

LYS 406 LYS 407 -0.0001

LYS 407 GLN 408 -0.0335

GLN 408 MET 409 -0.0003

MET 409 SER 410 0.0001

SER 410 GLU 411 -0.0003

GLU 411 HIS 412 0.0001

HIS 412 LEU 413 0.0001

LEU 413 SER 414 0.0003

SER 414 GLN 415 0.0001

GLN 415 LYS 416 -0.0001

LYS 416 GLU 417 0.0004

GLU 417 LYS 418 0.0000

LYS 418 GLU 419 0.0289

GLU 419 LEU 420 -0.0001

LEU 420 LYS 421 0.0001

LYS 421 ASN 422 0.0002

ASN 422 LYS 423 0.0002

LYS 423 GLU 424 -0.0004

GLU 424 ASN 425 -0.0002

ASN 425 PHE 426 0.0001

PHE 426 ILE 427 -0.0001

ILE 427 PHE 428 -0.0000

PHE 428 ASP 429 0.0001

ASP 429 LYS 430 0.0080

LYS 430 TYR 431 -0.0000

TYR 431 GLU 432 0.0002

GLU 432 SER 433 -0.0001

SER 433 GLY 434 0.0001

GLY 434 ILE 435 -0.0000

ILE 435 TYR 436 -0.0002

TYR 436 SER 437 0.0003

SER 437 ASP 438 0.0003

ASP 438 GLU 439 0.0004

GLU 439 LEU 440 -0.0000

LEU 440 PHE 441 -0.0027

PHE 441 LEU 442 -0.0001

LEU 442 LYS 443 0.0003

LYS 443 ARG 444 -0.0001

ARG 444 LYS 445 0.0003

LYS 445 ALA 446 0.0004

ALA 446 ALA 447 0.0003

ALA 447 LEU 448 0.0001

LEU 448 ASP 449 -0.0002

ASP 449 GLU 450 -0.0003

GLU 450 GLU 451 -0.0000

GLU 451 PHE 452 0.0023

PHE 452 LYS 453 -0.0003

LYS 453 GLU 454 0.0002

GLU 454 LEU 455 0.0002

LEU 455 GLN 456 0.0000

GLN 456 ASN 457 -0.0002

ASN 457 ALA 458 0.0006

ALA 458 LYS 459 -0.0002

LYS 459 ASN 460 0.0000

ASN 460 GLU 461 0.0001

GLU 461 LEU 462 0.0003

LEU 462 ASN 463 -0.0547

ASN 463 GLY 464 -0.0003

GLY 464 LEU 465 -0.0002

LEU 465 GLN 466 -0.0002

GLN 466 ASP 467 0.0003

ASP 467 THR 468 -0.0003

THR 468 GLN 469 -0.0003

GLN 469 SER 470 -0.0001

SER 470 GLU 471 0.0001

GLU 471 ILE 472 -0.0001

ILE 472 ASP 473 0.0003

ASP 473 SER 474 0.1196

SER 474 ASN 475 -0.0002

ASN 475 THR 476 0.0002

THR 476 VAL 477 -0.0002

VAL 477 ARG 478 -0.0001

ARG 478 ASN 479 0.0003

ASN 479 ASN 480 0.0001

ASN 480 ILE 481 -0.0000

ILE 481 ASN 482 0.0004

ASN 482 LYS 483 0.0002

LYS 483 ILE 484 -0.0001

ILE 484 ILE 485 0.0445

ILE 485 ASP 486 0.0000

ASP 486 GLN 487 -0.0001

GLN 487 TYR 488 -0.0002

TYR 488 HIS 489 0.0000

HIS 489 ILE 490 -0.0002

ILE 490 GLU 491 0.0004

GLU 491 SER 492 -0.0001

SER 492 SER 493 0.0004

SER 493 SER 494 -0.0001

SER 494 GLU 495 -0.0003

GLU 495 LYS 496 0.0082

LYS 496 LYS 497 -0.0001

LYS 497 ASN 498 -0.0000

ASN 498 GLU 499 -0.0000

GLU 499 LEU 500 0.0004

LEU 500 LEU 501 -0.0001

LEU 501 ARG 502 -0.0000

ARG 502 MET 503 0.0002

MET 503 VAL 504 0.0002

VAL 504 LEU 505 -0.0003

LEU 505 LYS 506 -0.0003

LYS 506 ASP 507 -0.1892

ASP 507 VAL 508 0.0001

VAL 508 ILE 509 -0.0000

ILE 509 VAL 510 -0.0002

VAL 510 ASN 511 0.0001

ASN 511 MET 512 0.0000

MET 512 THR 513 0.0001

THR 513 GLN 514 -0.0002

GLN 514 LYS 515 0.0001

LYS 515 ARG 516 -0.0002

ARG 516 LYS 517 -0.0003

LYS 517 GLY 518 0.0153

GLY 518 PRO 519 0.0002

PRO 519 ILE 520 -0.0001

ILE 520 PRO 521 0.0002

PRO 521 ALA 522 -0.0003

ALA 522 GLN 523 -0.0001

GLN 523 PHE 524 -0.0001

PHE 524 GLU 525 0.0002

GLU 525 ILE 526 -0.0002

ILE 526 THR 527 -0.0001

THR 527 PRO 528 0.0003

PRO 528 ILE 529 -0.0722

ILE 529 LEU 530 -0.0002

LEU 530 ARG 531 0.0002

ARG 531 PHE 532 0.0000

PHE 532 ASN 533 -0.0001

ASN 533 PHE 534 0.0002

PHE 534 ILE 535 0.0000

ILE 535 PHE 536 -0.0002

PHE 536 ASP 537 -0.0002

ASP 537 LEU 538 0.0003

LEU 538 THR 539 -0.0000

THR 539 ALA 540 0.0620

ALA 540 THR 541 0.0002

THR 541 ASN 542 0.0001

ASN 542 SER 543 -0.0001

SER 543 PHE 544 -0.0002

PHE 544 HIS 545 0.0002

HIS 545 MET 1 0.0429

MET 1 GLU 2 0.0003

GLU 2 LEU 3 0.0004

LEU 3 LYS 4 0.0002

LYS 4 ASN 5 -0.0000

ASN 5 ILE 6 0.0001

ILE 6 VAL 7 0.0000

VAL 7 ASN 8 -0.0004

ASN 8 SER 9 0.0001

SER 9 TYR 10 0.0003

TYR 10 ASN 11 -0.0001

ASN 11 ILE 12 -0.0304

ILE 12 THR 13 0.0001

THR 13 ASN 14 0.0003

ASN 14 ILE 15 -0.0001

ILE 15 LEU 16 0.0003

LEU 16 GLY 17 -0.0003

GLY 17 TYR 18 0.0001

TYR 18 LEU 19 -0.0003

LEU 19 ARG 20 0.0001

ARG 20 ARG 21 -0.0002

ARG 21 SER 22 0.0001

SER 22 ARG 23 0.0283

ARG 23 GLN 24 0.0001

GLN 24 ASP 25 -0.0001

ASP 25 MET 26 -0.0002

MET 26 GLU 27 -0.0001

GLU 27 ARG 28 0.0003

ARG 28 GLU 29 0.0001

GLU 29 LYS 30 0.0002

LYS 30 ARG 31 0.0001

ARG 31 THR 32 -0.0004

THR 32 GLY 33 0.0003

GLY 33 GLU 34 0.0041

GLU 34 ASP 35 -0.0001

ASP 35 THR 36 0.0001

THR 36 LEU 37 -0.0005

LEU 37 THR 38 0.0001

THR 38 GLU 39 0.0001

GLU 39 GLN 40 -0.0003

GLN 40 LYS 41 0.0001

LYS 41 GLU 42 -0.0001

GLU 42 LEU 43 0.0000

LEU 43 MET 44 -0.0000

MET 44 ASN 45 0.0029

ASN 45 LYS 46 0.0002

LYS 46 ILE 47 0.0000

ILE 47 LEU 48 -0.0001

LEU 48 THR 49 0.0000

THR 49 ALA 50 -0.0001

ALA 50 ILE 51 -0.0001

ILE 51 GLU 52 0.0002

GLU 52 ILE 53 0.0000

ILE 53 PRO 54 -0.0003

PRO 54 TYR 55 0.0001

TYR 55 GLU 56 0.0072

GLU 56 LEU 57 0.0001

LEU 57 LYS 58 0.0000

LYS 58 MET 59 -0.0003

MET 59 GLU 60 0.0001

GLU 60 ILE 61 -0.0003

ILE 61 GLY 62 0.0000

GLY 62 SER 63 -0.0002

SER 63 GLY 64 -0.0002

GLY 64 GLU 65 0.0002

GLU 65 SER 66 0.0002

SER 66 ILE 67 0.0162

ILE 67 ASP 68 -0.0000

ASP 68 GLY 69 -0.0002

GLY 69 ARG 70 -0.0002

ARG 70 PRO 71 -0.0001

PRO 71 VAL 72 -0.0000

VAL 72 PHE 73 -0.0000

PHE 73 LYS 74 -0.0001

LYS 74 GLU 75 0.0001

GLU 75 CYS 76 -0.0002

CYS 76 LEU 77 -0.0000

LEU 77 LYS 78 0.0040

LYS 78 ASP 79 0.0002

ASP 79 LEU 80 -0.0002

LEU 80 GLU 81 -0.0002

GLU 81 GLU 82 0.0000

GLU 82 GLY 83 0.0001

GLY 83 LYS 84 0.0000

LYS 84 TYR 85 0.0002

TYR 85 GLN 86 0.0001

GLN 86 ALA 87 -0.0002

ALA 87 ILE 88 -0.0001

ILE 88 ALA 89 -0.0001

ALA 89 VAL 90 -0.0003

VAL 90 LYS 91 0.0003

LYS 91 GLU 92 -0.0002

GLU 92 ILE 93 0.0002

ILE 93 THR 94 -0.0002

THR 94 ARG 95 -0.0003

ARG 95 LEU 96 0.0002

LEU 96 SER 97 -0.0002

SER 97 ARG 98 -0.0002

ARG 98 GLY 99 -0.0002

GLY 99 SER 100 -0.0199

SER 100 TYR 101 -0.0003

TYR 101 SER 102 0.0001

SER 102 ASP 103 0.0003

ASP 103 ALA 104 0.0002

ALA 104 GLY 105 -0.0003

GLY 105 GLN 106 0.0002

GLN 106 ILE 107 -0.0001

ILE 107 VAL 108 0.0000

VAL 108 ASN 109 0.0001

ASN 109 LEU 110 0.0004

LEU 110 LEU 111 -0.0059

LEU 111 GLN 112 -0.0001

GLN 112 SER 113 -0.0004

SER 113 LYS 114 -0.0001

LYS 114 ARG 115 -0.0001

ARG 115 LEU 116 -0.0000

LEU 116 ILE 117 0.0005

ILE 117 ILE 118 0.0002

ILE 118 ILE 119 -0.0001

ILE 119 THR 120 0.0000

THR 120 PRO 121 0.0001

PRO 121 TYR 122 0.0213

TYR 122 LYS 123 0.0003

LYS 123 VAL 124 -0.0000

VAL 124 TYR 125 -0.0001

TYR 125 ASP 126 -0.0001

ASP 126 PRO 127 0.0000

PRO 127 ARG 128 0.0003

ARG 128 ASN 129 -0.0001

ASN 129 PRO 130 0.0000

PRO 130 VAL 131 0.0000

VAL 131 ASP 132 0.0002

ASP 132 MET 133 0.0099

MET 133 ARG 134 0.0003

ARG 134 GLN 135 -0.0000

GLN 135 ILE 136 0.0002

ILE 136 ARG 137 -0.0000

ARG 137 PHE 138 0.0001

PHE 138 GLU 139 -0.0002

GLU 139 LEU 140 -0.0004

LEU 140 PHE 141 -0.0002

PHE 141 MET 142 0.0000

MET 142 ALA 143 -0.0002

ALA 143 ARG 144 -0.0290

ARG 144 GLU 145 0.0001

GLU 145 GLU 146 0.0003

GLU 146 PHE 147 -0.0001

PHE 147 GLU 148 -0.0003

GLU 148 MET 149 0.0001

MET 149 THR 150 0.0003

THR 150 ARG 151 0.0002

ARG 151 GLU 152 0.0003

GLU 152 ARG 153 -0.0000

ARG 153 MET 154 0.0001

MET 154 THR 155 0.0100

THR 155 GLY 156 -0.0003

GLY 156 ALA 157 0.0002

ALA 157 LYS 158 0.0001

LYS 158 TYR 159 0.0000

TYR 159 THR 160 0.0000

THR 160 TYR 161 0.0002

TYR 161 ALA 162 0.0001

ALA 162 ALA 163 -0.0002

ALA 163 GLN 164 -0.0000

GLN 164 GLY 165 0.0001

GLY 165 LYS 166 0.0162

LYS 166 TRP 167 -0.0000

TRP 167 ILE 168 0.0000

ILE 168 SER 169 0.0001

SER 169 GLY 170 -0.0001

GLY 170 LEU 171 0.0001

LEU 171 ALA 172 0.0003

ALA 172 PRO 173 -0.0001

PRO 173 TYR 174 0.0000

TYR 174 GLY 175 0.0001

GLY 175 TYR 176 -0.0001

TYR 176 GLN 177 0.0179

GLN 177 LEU 178 -0.0002

LEU 178 ASN 179 0.0004

ASN 179 LYS 180 -0.0002

LYS 180 LYS 181 -0.0004

LYS 181 THR 182 -0.0003

THR 182 SER 183 -0.0000

SER 183 LYS 184 -0.0003

LYS 184 LEU 185 -0.0000

LEU 185 ASP 186 0.0004

ASP 186 PRO 187 0.0001

PRO 187 VAL 188 0.0017

VAL 188 GLU 189 -0.0002

GLU 189 ASP 190 -0.0000

ASP 190 GLU 191 -0.0004

GLU 191 ALA 192 0.0003

ALA 192 LYS 193 0.0000

LYS 193 VAL 194 0.0001

VAL 194 VAL 195 0.0003

VAL 195 GLN 196 0.0001

GLN 196 LEU 197 0.0002

LEU 197 ILE 198 -0.0000

ILE 198 PHE 199 -0.0132

PHE 199 ASN 200 -0.0001

ASN 200 ILE 201 0.0004

ILE 201 PHE 202 0.0000

PHE 202 LEU 203 0.0003

LEU 203 ASN 204 0.0002

ASN 204 GLY 205 0.0001

GLY 205 LEU 206 -0.0001

LEU 206 ASN 207 -0.0003

ASN 207 GLY 208 -0.0001

GLY 208 LYS 209 0.0001

LYS 209 ASP 210 0.0071

ASP 210 TYR 211 -0.0002

TYR 211 SER 212 0.0000

SER 212 TYR 213 0.0001

TYR 213 THR 214 0.0001

THR 214 ALA 215 0.0004

ALA 215 ILE 216 -0.0001

ILE 216 ALA 217 -0.0002

ALA 217 SER 218 0.0002

SER 218 HIS 219 -0.0004

HIS 219 LEU 220 0.0002

LEU 220 THR 221 0.0003

THR 221 ASN 222 -0.0000

ASN 222 LEU 223 -0.0002

LEU 223 GLN 224 -0.0001

GLN 224 ILE 225 -0.0003

ILE 225 PRO 226 -0.0002

PRO 226 THR 227 -0.0004

THR 227 PRO 228 0.0002

PRO 228 SER 229 0.0002

SER 229 GLY 230 -0.0000

GLY 230 LYS 231 0.0004

LYS 231 LYS 232 0.0119

LYS 232 ARG 233 0.0002

ARG 233 TRP 234 0.0001

TRP 234 ASN 235 -0.0001

ASN 235 GLN 236 0.0001

GLN 236 TYR 237 -0.0002

TYR 237 THR 238 0.0003

THR 238 ILE 239 -0.0004

ILE 239 LYS 240 0.0002

LYS 240 ALA 241 0.0002

ALA 241 ILE 242 0.0001

ILE 242 LEU 243 -0.0076

LEU 243 GLN 244 -0.0001

GLN 244 ASN 245 -0.0002

ASN 245 GLU 246 0.0002

GLU 246 VAL 247 0.0001

VAL 247 TYR 248 -0.0002

TYR 248 ILE 249 -0.0001

ILE 249 GLY 250 -0.0003

GLY 250 THR 251 -0.0001

THR 251 VAL 252 0.0001

VAL 252 LYS 253 -0.0001

LYS 253 TYR 254 0.1255

TYR 254 LYS 255 -0.0001

LYS 255 VAL 256 0.0002

VAL 256 ARG 257 -0.0003

ARG 257 GLU 258 0.0002

GLU 258 LYS 259 0.0000

LYS 259 THR 260 -0.0004

THR 260 LYS 261 0.0001

LYS 261 ASP 262 0.0006

ASP 262 GLY 263 0.0003

GLY 263 LYS 264 -0.0003

LYS 264 ARG 265 0.0009

ARG 265 THR 266 0.0001

THR 266 ILE 267 0.0001

ILE 267 ARG 268 0.0001

ARG 268 PRO 269 -0.0001

PRO 269 GLU 270 -0.0002

GLU 270 LYS 271 0.0001

LYS 271 GLU 272 0.0004

GLU 272 GLN 273 -0.0002

GLN 273 ILE 274 0.0001

ILE 274 VAL 275 0.0003

VAL 275 VAL 276 -0.0028

VAL 276 GLN 277 0.0001

GLN 277 ASP 278 -0.0002

ASP 278 ALA 279 0.0001

ALA 279 HIS 280 -0.0000

HIS 280 ALA 281 0.0000

ALA 281 PRO 282 0.0002

PRO 282 ILE 283 -0.0004

ILE 283 ILE 284 -0.0002

ILE 284 ASP 285 0.0000

ASP 285 LYS 286 0.0001

LYS 286 GLU 287 0.0229

GLU 287 GLN 288 0.0003

GLN 288 PHE 289 -0.0003

PHE 289 GLN 290 0.0000

GLN 290 GLN 291 -0.0001

GLN 291 SER 292 -0.0000

SER 292 GLN 293 0.0004

GLN 293 VAL 294 -0.0003

VAL 294 LYS 295 0.0001

LYS 295 ILE 296 -0.0000

ILE 296 ALA 297 0.0001

ALA 297 ASN 298 0.0802

ASN 298 LYS 299 0.0005

LYS 299 VAL 300 0.0002

VAL 300 PRO 301 0.0000

PRO 301 LEU 302 -0.0000

LEU 302 LEU 303 -0.0002

LEU 303 PRO 304 0.0003

PRO 304 ASN 305 -0.0002

ASN 305 LYS 306 0.0000

LYS 306 ASP 307 0.0002

ASP 307 GLU 308 0.0000

GLU 308 PHE 309 -0.0002

PHE 309 GLU 310 -0.0003

GLU 310 LEU 311 0.0001

LEU 311 SER 312 -0.0003

SER 312 GLU 313 0.0003

GLU 313 LEU 314 0.0002

LEU 314 ALA 315 -0.0003

ALA 315 GLY 316 0.0003

GLY 316 VAL 317 0.0001

VAL 317 CYS 318 0.0002

CYS 318 THR 319 0.0002

THR 319 CYS 320 -0.0469

CYS 320 SER 321 0.0003

SER 321 LYS 322 -0.0002

LYS 322 CYS 323 -0.0000

CYS 323 GLY 324 -0.0001

GLY 324 GLU 325 0.0006

GLU 325 PRO 326 -0.0001

PRO 326 LEU 327 0.0001

LEU 327 SER 328 -0.0001

SER 328 LYS 329 0.0000

LYS 329 TYR 330 0.0002

TYR 330 GLU 331 0.0058

GLU 331 SER 332 -0.0006

SER 332 LYS 333 0.0003

LYS 333 ARG 334 -0.0001

ARG 334 ILE 335 -0.0001

ILE 335 ARG 336 0.0001

ARG 336 LYS 337 -0.0001

LYS 337 ASN 338 -0.0002

ASN 338 LYS 339 -0.0003

LYS 339 ASP 340 0.0004

ASP 340 GLY 341 0.0000

GLY 341 THR 342 0.0422

THR 342 GLU 343 0.0001

GLU 343 SER 344 -0.0003

SER 344 VAL 345 -0.0000

VAL 345 TYR 346 -0.0003

TYR 346 HIS 347 0.0003

HIS 347 VAL 348 0.0000

VAL 348 LYS 349 -0.0000

LYS 349 SER 350 -0.0003

SER 350 LEU 351 -0.0001

LEU 351 THR 352 -0.0000

THR 352 CYS 353 -0.0597

CYS 353 LYS 354 0.0003

LYS 354 LYS 355 0.0003

LYS 355 ASN 356 0.0000

ASN 356 LYS 357 -0.0000

LYS 357 CYS 358 -0.0000

CYS 358 THR 359 0.0000

THR 359 TYR 360 -0.0000

TYR 360 VAL 361 0.0001

VAL 361 ARG 362 -0.0002

ARG 362 TYR 363 -0.0003

TYR 363 ASN 364 0.0412

ASN 364 ASP 365 -0.0000

ASP 365 VAL 366 0.0002

VAL 366 GLU 367 0.0000

GLU 367 ASN 368 0.0000

ASN 368 ALA 369 -0.0004

ALA 369 ILE 370 0.0002

ILE 370 LEU 371 -0.0002

LEU 371 ASP 372 0.0001

ASP 372 TYR 373 -0.0003

TYR 373 LEU 374 -0.0001

LEU 374 SER 375 -0.0356

SER 375 SER 376 0.0000

SER 376 LEU 377 0.0001

LEU 377 ASN 378 -0.0002

ASN 378 ASP 379 -0.0003

ASP 379 LEU 380 -0.0000

LEU 380 ASN 381 -0.0000

ASN 381 ASP 382 -0.0001

ASP 382 SER 383 -0.0001

SER 383 THR 384 -0.0003

THR 384 LEU 385 -0.0001

LEU 385 THR 386 0.0173

THR 386 LYS 387 -0.0003

LYS 387 HIS 388 0.0001

HIS 388 ILE 389 -0.0001

ILE 389 ASN 390 -0.0001

ASN 390 SER 391 -0.0001

SER 391 MET 392 0.0002

MET 392 LEU 393 0.0003

LEU 393 SER 394 0.0002

SER 394 LYS 395 0.0000

LYS 395 TYR 396 -0.0000

TYR 396 GLU 397 -0.0578

GLU 397 ASP 398 -0.0001

ASP 398 ASP 399 -0.0003

ASP 399 ASN 400 0.0001

ASN 400 SER 401 0.0001

SER 401 ASN 402 -0.0002

ASN 402 MET 403 0.0005

MET 403 LYS 404 0.0002

LYS 404 THR 405 -0.0005

THR 405 LYS 406 -0.0001

LYS 406 LYS 407 -0.0002

LYS 407 GLN 408 0.0093

GLN 408 MET 409 -0.0001

MET 409 SER 410 0.0003

SER 410 GLU 411 -0.0001

GLU 411 HIS 412 -0.0004

HIS 412 LEU 413 0.0000

LEU 413 SER 414 -0.0001

SER 414 GLN 415 -0.0001

GLN 415 LYS 416 -0.0002

LYS 416 GLU 417 0.0001

GLU 417 LYS 418 -0.0002

LYS 418 GLU 419 -0.0246

GLU 419 LEU 420 -0.0001

LEU 420 LYS 421 0.0001

LYS 421 ASN 422 -0.0001

ASN 422 LYS 423 0.0002

LYS 423 GLU 424 0.0001

GLU 424 ASN 425 -0.0000

ASN 425 PHE 426 -0.0001

PHE 426 ILE 427 0.0005

ILE 427 PHE 428 -0.0002

PHE 428 ASP 429 -0.0004

ASP 429 LYS 430 -0.0187

LYS 430 TYR 431 -0.0001

TYR 431 GLU 432 0.0001

GLU 432 SER 433 -0.0003

SER 433 GLY 434 0.0002

GLY 434 ILE 435 -0.0002

ILE 435 TYR 436 0.0002

TYR 436 SER 437 -0.0001

SER 437 ASP 438 -0.0000

ASP 438 GLU 439 0.0002

GLU 439 LEU 440 0.0002

LEU 440 PHE 441 -0.0117

PHE 441 LEU 442 0.0006

LEU 442 LYS 443 -0.0001

LYS 443 ARG 444 -0.0000

ARG 444 LYS 445 0.0000

LYS 445 ALA 446 -0.0002

ALA 446 ALA 447 -0.0001

ALA 447 LEU 448 -0.0001

LEU 448 ASP 449 0.0003

ASP 449 GLU 450 0.0001

GLU 450 GLU 451 -0.0002

GLU 451 PHE 452 0.0323

PHE 452 LYS 453 0.0003

LYS 453 GLU 454 0.0001

GLU 454 LEU 455 -0.0001

LEU 455 GLN 456 -0.0001

GLN 456 ASN 457 -0.0000

ASN 457 ALA 458 -0.0003

ALA 458 LYS 459 -0.0002

LYS 459 ASN 460 0.0003

ASN 460 GLU 461 -0.0001

GLU 461 LEU 462 0.0000

LEU 462 ASN 463 0.0882

ASN 463 GLY 464 0.0001

GLY 464 LEU 465 0.0002

LEU 465 GLN 466 0.0002

GLN 466 ASP 467 -0.0004

ASP 467 THR 468 0.0003

THR 468 GLN 469 0.0002

GLN 469 SER 470 0.0001

SER 470 GLU 471 0.0001

GLU 471 ILE 472 -0.0001

ILE 472 ASP 473 -0.0001

ASP 473 SER 474 0.1089

SER 474 ASN 475 0.0000

ASN 475 THR 476 -0.0006

THR 476 VAL 477 0.0005

VAL 477 ARG 478 -0.0001

ARG 478 ASN 479 0.0001

ASN 479 ASN 480 0.0000

ASN 480 ILE 481 -0.0002

ILE 481 ASN 482 0.0002

ASN 482 LYS 483 0.0001

LYS 483 ILE 484 0.0002

ILE 484 ILE 485 0.0229

ILE 485 ASP 486 -0.0001

ASP 486 GLN 487 -0.0001

GLN 487 TYR 488 0.0003

TYR 488 HIS 489 -0.0002

HIS 489 ILE 490 0.0001

ILE 490 GLU 491 -0.0001

GLU 491 SER 492 -0.0002

SER 492 SER 493 -0.0001

SER 493 SER 494 -0.0002

SER 494 GLU 495 -0.0002

GLU 495 LYS 496 0.0074

LYS 496 LYS 497 -0.0001

LYS 497 ASN 498 -0.0001

ASN 498 GLU 499 0.0004

GLU 499 LEU 500 -0.0001

LEU 500 LEU 501 0.0002

LEU 501 ARG 502 -0.0001

ARG 502 MET 503 0.0003

MET 503 VAL 504 -0.0000

VAL 504 LEU 505 0.0003

LEU 505 LYS 506 0.0003

LYS 506 ASP 507 -0.0686

ASP 507 VAL 508 0.0000

VAL 508 ILE 509 0.0004

ILE 509 VAL 510 0.0001

VAL 510 ASN 511 -0.0003

ASN 511 MET 512 0.0002

MET 512 THR 513 -0.0001

THR 513 GLN 514 0.0002

GLN 514 LYS 515 0.0002

LYS 515 ARG 516 -0.0002

ARG 516 LYS 517 0.0002

LYS 517 GLY 518 0.0057

GLY 518 PRO 519 -0.0001

PRO 519 ILE 520 -0.0001

ILE 520 PRO 521 -0.0001

PRO 521 ALA 522 0.0001

ALA 522 GLN 523 0.0002

GLN 523 PHE 524 0.0000

PHE 524 GLU 525 0.0002

GLU 525 ILE 526 -0.0001

ILE 526 THR 527 0.0003

THR 527 PRO 528 -0.0005

PRO 528 ILE 529 -0.0046

ILE 529 LEU 530 0.0001

LEU 530 ARG 531 0.0000

ARG 531 PHE 532 -0.0000

PHE 532 ASN 533 -0.0001

ASN 533 PHE 534 -0.0001

PHE 534 ILE 535 -0.0002

ILE 535 PHE 536 -0.0000

PHE 536 ASP 537 -0.0000

ASP 537 LEU 538 -0.0001

LEU 538 THR 539 0.0003

THR 539 ALA 540 0.0259

ALA 540 THR 541 -0.0002

THR 541 ASN 542 0.0000

ASN 542 SER 543 0.0000

SER 543 PHE 544 0.0002

PHE 544 HIS 545 0.0002

HIS 545 MET 1 0.0888

MET 1 GLU 2 -0.0004

GLU 2 LEU 3 0.0001

LEU 3 LYS 4 0.0002

LYS 4 ASN 5 -0.0003

ASN 5 ILE 6 0.0003

ILE 6 VAL 7 0.0002

VAL 7 ASN 8 -0.0001

ASN 8 SER 9 -0.0004

SER 9 TYR 10 -0.0000

TYR 10 ASN 11 0.0003

ASN 11 ILE 12 -0.0482

ILE 12 THR 13 -0.0001

THR 13 ASN 14 0.0001

ASN 14 ILE 15 0.0002

ILE 15 LEU 16 -0.0000

LEU 16 GLY 17 0.0002

GLY 17 TYR 18 0.0001

TYR 18 LEU 19 -0.0001

LEU 19 ARG 20 0.0002

ARG 20 ARG 21 -0.0000

ARG 21 SER 22 -0.0002

SER 22 ARG 23 0.0276

ARG 23 GLN 24 0.0001

GLN 24 ASP 25 -0.0003

ASP 25 MET 26 -0.0002

MET 26 GLU 27 0.0003

GLU 27 ARG 28 -0.0000

ARG 28 GLU 29 -0.0000

GLU 29 LYS 30 0.0001

LYS 30 ARG 31 -0.0002

ARG 31 THR 32 -0.0001

THR 32 GLY 33 -0.0001

GLY 33 GLU 34 0.0029

GLU 34 ASP 35 0.0001

ASP 35 THR 36 0.0002

THR 36 LEU 37 -0.0002

LEU 37 THR 38 0.0002

THR 38 GLU 39 -0.0005

GLU 39 GLN 40 0.0003

GLN 40 LYS 41 0.0001

LYS 41 GLU 42 0.0004

GLU 42 LEU 43 0.0001

LEU 43 MET 44 -0.0000

MET 44 ASN 45 0.0013

ASN 45 LYS 46 -0.0002

LYS 46 ILE 47 -0.0004

ILE 47 LEU 48 0.0001

LEU 48 THR 49 0.0003

THR 49 ALA 50 -0.0001

ALA 50 ILE 51 0.0001

ILE 51 GLU 52 0.0001

GLU 52 ILE 53 -0.0003

ILE 53 PRO 54 -0.0000

PRO 54 TYR 55 -0.0003

TYR 55 GLU 56 0.0207

GLU 56 LEU 57 -0.0001

LEU 57 LYS 58 -0.0004

LYS 58 MET 59 0.0004

MET 59 GLU 60 0.0002

GLU 60 ILE 61 -0.0001

ILE 61 GLY 62 0.0003

GLY 62 SER 63 -0.0001

SER 63 GLY 64 0.0002

GLY 64 GLU 65 0.0000

GLU 65 SER 66 0.0001

SER 66 ILE 67 0.0435

ILE 67 ASP 68 -0.0000

ASP 68 GLY 69 0.0003

GLY 69 ARG 70 0.0001

ARG 70 PRO 71 -0.0000

PRO 71 VAL 72 0.0002

VAL 72 PHE 73 0.0001

PHE 73 LYS 74 0.0004

LYS 74 GLU 75 -0.0002

GLU 75 CYS 76 -0.0000

CYS 76 LEU 77 0.0002

LEU 77 LYS 78 0.0086

LYS 78 ASP 79 -0.0002

ASP 79 LEU 80 -0.0005

LEU 80 GLU 81 -0.0002

GLU 81 GLU 82 0.0004

GLU 82 GLY 83 0.0002

GLY 83 LYS 84 0.0003

LYS 84 TYR 85 -0.0001

TYR 85 GLN 86 0.0001

GLN 86 ALA 87 0.0002

ALA 87 ILE 88 -0.0005

ILE 88 ALA 89 -0.0203

ALA 89 VAL 90 -0.0004

VAL 90 LYS 91 0.0001

LYS 91 GLU 92 -0.0004

GLU 92 ILE 93 -0.0000

ILE 93 THR 94 -0.0001

THR 94 ARG 95 0.0003

ARG 95 LEU 96 -0.0004

LEU 96 SER 97 0.0005

SER 97 ARG 98 -0.0001

ARG 98 GLY 99 -0.0002

GLY 99 SER 100 -0.0157

SER 100 TYR 101 0.0003

TYR 101 SER 102 -0.0001

SER 102 ASP 103 0.0003

ASP 103 ALA 104 0.0002

ALA 104 GLY 105 0.0001

GLY 105 GLN 106 0.0004

GLN 106 ILE 107 0.0000

ILE 107 VAL 108 -0.0001

VAL 108 ASN 109 -0.0000

ASN 109 LEU 110 0.0000

LEU 110 LEU 111 0.0156

LEU 111 GLN 112 0.0001

GLN 112 SER 113 0.0001

SER 113 LYS 114 -0.0003

LYS 114 ARG 115 0.0001

ARG 115 LEU 116 -0.0005

LEU 116 ILE 117 0.0003

ILE 117 ILE 118 0.0002

ILE 118 ILE 119 0.0000

ILE 119 THR 120 -0.0003

THR 120 PRO 121 -0.0001

PRO 121 TYR 122 0.0082

TYR 122 LYS 123 0.0000

LYS 123 VAL 124 -0.0001

VAL 124 TYR 125 0.0001

TYR 125 ASP 126 -0.0002

ASP 126 PRO 127 -0.0000

PRO 127 ARG 128 -0.0001

ARG 128 ASN 129 -0.0000

ASN 129 PRO 130 0.0001

PRO 130 VAL 131 -0.0000

VAL 131 ASP 132 0.0004

ASP 132 MET 133 0.0203

MET 133 ARG 134 0.0000

ARG 134 GLN 135 -0.0000

GLN 135 ILE 136 -0.0002

ILE 136 ARG 137 -0.0003

ARG 137 PHE 138 -0.0001

PHE 138 GLU 139 -0.0000

GLU 139 LEU 140 0.0001

LEU 140 PHE 141 -0.0002

PHE 141 MET 142 -0.0004

MET 142 ALA 143 -0.0001

ALA 143 ARG 144 -0.0281

ARG 144 GLU 145 -0.0001

GLU 145 GLU 146 -0.0001

GLU 146 PHE 147 -0.0002

PHE 147 GLU 148 -0.0002

GLU 148 MET 149 -0.0000

MET 149 THR 150 -0.0001

THR 150 ARG 151 -0.0005

ARG 151 GLU 152 0.0001

GLU 152 ARG 153 -0.0000

ARG 153 MET 154 -0.0003

MET 154 THR 155 -0.0979

THR 155 GLY 156 0.0005

GLY 156 ALA 157 0.0000

ALA 157 LYS 158 0.0001

LYS 158 TYR 159 -0.0001

TYR 159 THR 160 0.0000

THR 160 TYR 161 0.0000

TYR 161 ALA 162 -0.0002

ALA 162 ALA 163 -0.0002

ALA 163 GLN 164 0.0002

GLN 164 GLY 165 -0.0001

GLY 165 LYS 166 -0.0322

LYS 166 TRP 167 0.0004

TRP 167 ILE 168 -0.0001

ILE 168 SER 169 0.0000

SER 169 GLY 170 -0.0003

GLY 170 LEU 171 -0.0000

LEU 171 ALA 172 -0.0001

ALA 172 PRO 173 -0.0003

PRO 173 TYR 174 0.0003

TYR 174 GLY 175 -0.0001

GLY 175 TYR 176 -0.0000

TYR 176 GLN 177 -0.0069

GLN 177 LEU 178 0.0002

LEU 178 ASN 179 -0.0001

ASN 179 LYS 180 -0.0001

LYS 180 LYS 181 0.0001

LYS 181 THR 182 -0.0004

THR 182 SER 183 0.0000

SER 183 LYS 184 0.0001

LYS 184 LEU 185 -0.0001

LEU 185 ASP 186 0.0002

ASP 186 PRO 187 0.0000

PRO 187 VAL 188 -0.0063

VAL 188 GLU 189 0.0002

GLU 189 ASP 190 -0.0002

ASP 190 GLU 191 -0.0001

GLU 191 ALA 192 -0.0001

ALA 192 LYS 193 0.0001

LYS 193 VAL 194 -0.0001

VAL 194 VAL 195 0.0003

VAL 195 GLN 196 0.0001

GLN 196 LEU 197 0.0003

LEU 197 ILE 198 0.0003

ILE 198 PHE 199 0.0121

PHE 199 ASN 200 0.0002

ASN 200 ILE 201 -0.0001

ILE 201 PHE 202 -0.0000

PHE 202 LEU 203 0.0000

LEU 203 ASN 204 -0.0004

ASN 204 GLY 205 0.0002

GLY 205 LEU 206 0.0001

LEU 206 ASN 207 -0.0000

ASN 207 GLY 208 -0.0003

GLY 208 LYS 209 -0.0001

LYS 209 ASP 210 -0.0241

ASP 210 TYR 211 0.0001

TYR 211 SER 212 0.0000

SER 212 TYR 213 -0.0001

TYR 213 THR 214 0.0003

THR 214 ALA 215 -0.0001

ALA 215 ILE 216 0.0002

ILE 216 ALA 217 -0.0003

ALA 217 SER 218 -0.0002

SER 218 HIS 219 -0.0000

HIS 219 LEU 220 -0.0001

LEU 220 THR 221 0.0025

THR 221 ASN 222 0.0002

ASN 222 LEU 223 -0.0002

LEU 223 GLN 224 0.0001

GLN 224 ILE 225 -0.0000

ILE 225 PRO 226 -0.0001

PRO 226 THR 227 -0.0004

THR 227 PRO 228 -0.0003

PRO 228 SER 229 -0.0002

SER 229 GLY 230 0.0001

GLY 230 LYS 231 0.0001

LYS 231 LYS 232 -0.0403

LYS 232 ARG 233 -0.0001

ARG 233 TRP 234 -0.0001

TRP 234 ASN 235 -0.0001

ASN 235 GLN 236 0.0001

GLN 236 TYR 237 0.0004

TYR 237 THR 238 0.0003

THR 238 ILE 239 -0.0001

ILE 239 LYS 240 0.0000

LYS 240 ALA 241 -0.0002

ALA 241 ILE 242 -0.0003

ILE 242 LEU 243 0.0237

LEU 243 GLN 244 -0.0002

GLN 244 ASN 245 0.0002

ASN 245 GLU 246 -0.0000

GLU 246 VAL 247 0.0000

VAL 247 TYR 248 0.0001

TYR 248 ILE 249 -0.0003

ILE 249 GLY 250 0.0003

GLY 250 THR 251 -0.0003

THR 251 VAL 252 0.0002

VAL 252 LYS 253 0.0001

LYS 253 TYR 254 -0.2801

TYR 254 LYS 255 0.0002

LYS 255 VAL 256 -0.0000

VAL 256 ARG 257 0.0002

ARG 257 GLU 258 -0.0002

GLU 258 LYS 259 0.0000

LYS 259 THR 260 0.0005

THR 260 LYS 261 -0.0002

LYS 261 ASP 262 0.0002

ASP 262 GLY 263 -0.0002

GLY 263 LYS 264 -0.0002

LYS 264 ARG 265 0.0476

ARG 265 THR 266 -0.0001

THR 266 ILE 267 0.0002

ILE 267 ARG 268 -0.0004

ARG 268 PRO 269 0.0002

PRO 269 GLU 270 -0.0001

GLU 270 LYS 271 -0.0002

LYS 271 GLU 272 0.0001

GLU 272 GLN 273 -0.0001

GLN 273 ILE 274 -0.0003

ILE 274 VAL 275 -0.0000

VAL 275 VAL 276 -0.0955

VAL 276 GLN 277 -0.0002

GLN 277 ASP 278 -0.0001

ASP 278 ALA 279 0.0003

ALA 279 HIS 280 0.0002

HIS 280 ALA 281 0.0001

ALA 281 PRO 282 0.0001

PRO 282 ILE 283 -0.0001

ILE 283 ILE 284 -0.0000

ILE 284 ASP 285 0.0001

ASP 285 LYS 286 0.0002

LYS 286 GLU 287 -0.0144

GLU 287 GLN 288 -0.0003

GLN 288 PHE 289 0.0002

PHE 289 GLN 290 0.0002

GLN 290 GLN 291 -0.0002

GLN 291 SER 292 -0.0000

SER 292 GLN 293 0.0003

GLN 293 VAL 294 -0.0004

VAL 294 LYS 295 0.0000

LYS 295 ILE 296 -0.0002

ILE 296 ALA 297 0.0002

ALA 297 ASN 298 0.0155

ASN 298 LYS 299 -0.0001

LYS 299 VAL 300 0.0000

VAL 300 PRO 301 0.0000

PRO 301 LEU 302 0.0003

LEU 302 LEU 303 0.0002

LEU 303 PRO 304 -0.0003

PRO 304 ASN 305 0.0003

ASN 305 LYS 306 -0.0003

LYS 306 ASP 307 -0.0001

ASP 307 GLU 308 -0.0001

GLU 308 PHE 309 0.1343

PHE 309 GLU 310 0.0003

GLU 310 LEU 311 0.0002

LEU 311 SER 312 -0.0001

SER 312 GLU 313 0.0001

GLU 313 LEU 314 -0.0001

LEU 314 ALA 315 -0.0000

ALA 315 GLY 316 -0.0001

GLY 316 VAL 317 -0.0004

VAL 317 CYS 318 -0.0002

CYS 318 THR 319 -0.0000

THR 319 CYS 320 -0.0546

CYS 320 SER 321 0.0001

SER 321 LYS 322 0.0001

LYS 322 CYS 323 0.0000

CYS 323 GLY 324 -0.0000

GLY 324 GLU 325 -0.0001

GLU 325 PRO 326 -0.0003

PRO 326 LEU 327 0.0001

LEU 327 SER 328 0.0001

SER 328 LYS 329 -0.0001

LYS 329 TYR 330 -0.0005

TYR 330 GLU 331 -0.0111

GLU 331 SER 332 0.0002

SER 332 LYS 333 -0.0004

LYS 333 ARG 334 -0.0001

ARG 334 ILE 335 0.0002

ILE 335 ARG 336 0.0001

ARG 336 LYS 337 -0.0000

LYS 337 ASN 338 0.0002

ASN 338 LYS 339 0.0000

LYS 339 ASP 340 0.0001

ASP 340 GLY 341 -0.0003

GLY 341 THR 342 0.0577

THR 342 GLU 343 0.0002

GLU 343 SER 344 -0.0003

SER 344 VAL 345 -0.0004

VAL 345 TYR 346 -0.0000

TYR 346 HIS 347 0.0002

HIS 347 VAL 348 -0.0004

VAL 348 LYS 349 0.0004

LYS 349 SER 350 -0.0001

SER 350 LEU 351 0.0001

LEU 351 THR 352 0.0002

THR 352 CYS 353 -0.0968

CYS 353 LYS 354 0.0000

LYS 354 LYS 355 0.0002

LYS 355 ASN 356 0.0001

ASN 356 LYS 357 0.0001

LYS 357 CYS 358 -0.0000

CYS 358 THR 359 -0.0001

THR 359 TYR 360 0.0001

TYR 360 VAL 361 -0.0001

VAL 361 ARG 362 0.0004

ARG 362 TYR 363 -0.0001

TYR 363 ASN 364 0.0474

ASN 364 ASP 365 0.0002

ASP 365 VAL 366 -0.0002

VAL 366 GLU 367 -0.0001

GLU 367 ASN 368 0.0005

ASN 368 ALA 369 -0.0002

ALA 369 ILE 370 0.0002

ILE 370 LEU 371 0.0001

LEU 371 ASP 372 0.0003

ASP 372 TYR 373 -0.0002

TYR 373 LEU 374 0.0001

LEU 374 SER 375 -0.0463

SER 375 SER 376 0.0002

SER 376 LEU 377 0.0000

LEU 377 ASN 378 0.0001

ASN 378 ASP 379 -0.0000

ASP 379 LEU 380 -0.0001

LEU 380 ASN 381 -0.0002

ASN 381 ASP 382 -0.0002

ASP 382 SER 383 0.0001

SER 383 THR 384 0.0001

THR 384 LEU 385 -0.0002

LEU 385 THR 386 0.0210

THR 386 LYS 387 0.0003

LYS 387 HIS 388 0.0001

HIS 388 ILE 389 0.0000

ILE 389 ASN 390 -0.0000

ASN 390 SER 391 -0.0002

SER 391 MET 392 0.0004

MET 392 LEU 393 -0.0004

LEU 393 SER 394 0.0002

SER 394 LYS 395 0.0001

LYS 395 TYR 396 0.0004

TYR 396 GLU 397 -0.1905

GLU 397 ASP 398 -0.0000

ASP 398 ASP 399 -0.0001

ASP 399 ASN 400 0.0001

ASN 400 SER 401 -0.0001

SER 401 ASN 402 0.0000

ASN 402 MET 403 0.0000

MET 403 LYS 404 -0.0005

LYS 404 THR 405 0.0001

THR 405 LYS 406 -0.0003

LYS 406 LYS 407 0.0002

LYS 407 GLN 408 -0.0379

GLN 408 MET 409 -0.0000

MET 409 SER 410 -0.0000

SER 410 GLU 411 0.0000

GLU 411 HIS 412 -0.0003

HIS 412 LEU 413 0.0002

LEU 413 SER 414 0.0000

SER 414 GLN 415 -0.0002

GLN 415 LYS 416 -0.0001

LYS 416 GLU 417 0.0000

GLU 417 LYS 418 -0.0001

LYS 418 GLU 419 0.0114

GLU 419 LEU 420 -0.0001

LEU 420 LYS 421 -0.0002

LYS 421 ASN 422 -0.0003

ASN 422 LYS 423 -0.0002

LYS 423 GLU 424 -0.0002

GLU 424 ASN 425 -0.0000

ASN 425 PHE 426 0.0003

PHE 426 ILE 427 0.0001

ILE 427 PHE 428 0.0001

PHE 428 ASP 429 -0.0001

ASP 429 LYS 430 -0.0425

LYS 430 TYR 431 0.0001

TYR 431 GLU 432 -0.0002

GLU 432 SER 433 0.0000

SER 433 GLY 434 -0.0001

GLY 434 ILE 435 0.0002

ILE 435 TYR 436 0.0001

TYR 436 SER 437 -0.0002

SER 437 ASP 438 -0.0001

ASP 438 GLU 439 0.0001

GLU 439 LEU 440 0.0000

LEU 440 PHE 441 -0.0282

PHE 441 LEU 442 -0.0003

LEU 442 LYS 443 -0.0003

LYS 443 ARG 444 0.0002

ARG 444 LYS 445 -0.0001

LYS 445 ALA 446 -0.0002

ALA 446 ALA 447 0.0006

ALA 447 LEU 448 0.0001

LEU 448 ASP 449 0.0001

ASP 449 GLU 450 -0.0001

GLU 450 GLU 451 0.0003

GLU 451 PHE 452 -0.0139

PHE 452 LYS 453 -0.0000

LYS 453 GLU 454 -0.0000

GLU 454 LEU 455 -0.0001

LEU 455 GLN 456 0.0001

GLN 456 ASN 457 0.0001

ASN 457 ALA 458 0.0004

ALA 458 LYS 459 -0.0001

LYS 459 ASN 460 0.0000

ASN 460 GLU 461 -0.0002

GLU 461 LEU 462 -0.0000

LEU 462 ASN 463 -0.0344

ASN 463 GLY 464 0.0002

GLY 464 LEU 465 0.0002

LEU 465 GLN 466 0.0001

GLN 466 ASP 467 -0.0003

ASP 467 THR 468 0.0001

THR 468 GLN 469 0.0003

GLN 469 SER 470 0.0000

SER 470 GLU 471 -0.0001

GLU 471 ILE 472 -0.0002

ILE 472 ASP 473 -0.0001

ASP 473 SER 474 0.1269

SER 474 ASN 475 0.0001

ASN 475 THR 476 0.0003

THR 476 VAL 477 0.0003

VAL 477 ARG 478 0.0002

ARG 478 ASN 479 -0.0003

ASN 479 ASN 480 0.0000

ASN 480 ILE 481 0.0002

ILE 481 ASN 482 -0.0000

ASN 482 LYS 483 0.0000

LYS 483 ILE 484 0.0001

ILE 484 ILE 485 0.0367

ILE 485 ASP 486 0.0003

ASP 486 GLN 487 -0.0001

GLN 487 TYR 488 0.0000

TYR 488 HIS 489 0.0001

HIS 489 ILE 490 0.0000

ILE 490 GLU 491 0.0000

GLU 491 SER 492 -0.0002

SER 492 SER 493 0.0001

SER 493 SER 494 -0.0001

SER 494 GLU 495 -0.0001

GLU 495 LYS 496 0.0006

LYS 496 LYS 497 -0.0002

LYS 497 ASN 498 -0.0000

ASN 498 GLU 499 0.0001

GLU 499 LEU 500 0.0002

LEU 500 LEU 501 -0.0001

LEU 501 ARG 502 -0.0000

ARG 502 MET 503 0.0004

MET 503 VAL 504 -0.0001

VAL 504 LEU 505 0.0004

LEU 505 LYS 506 -0.0001

LYS 506 ASP 507 -0.1414

ASP 507 VAL 508 0.0003

VAL 508 ILE 509 0.0003

ILE 509 VAL 510 -0.0002

VAL 510 ASN 511 -0.0002

ASN 511 MET 512 -0.0002

MET 512 THR 513 -0.0002

THR 513 GLN 514 0.0002

GLN 514 LYS 515 -0.0006

LYS 515 ARG 516 -0.0001

ARG 516 LYS 517 -0.0000

LYS 517 GLY 518 0.0098

GLY 518 PRO 519 0.0000

PRO 519 ILE 520 0.0001

ILE 520 PRO 521 -0.0002

PRO 521 ALA 522 0.0003

ALA 522 GLN 523 -0.0002

GLN 523 PHE 524 -0.0001

PHE 524 GLU 525 0.0001

GLU 525 ILE 526 -0.0004

ILE 526 THR 527 0.0001

THR 527 PRO 528 0.0001

PRO 528 ILE 529 -0.0487

ILE 529 LEU 530 0.0002

LEU 530 ARG 531 -0.0002

ARG 531 PHE 532 0.0002

PHE 532 ASN 533 -0.0003

ASN 533 PHE 534 0.0000

PHE 534 ILE 535 0.0003

ILE 535 PHE 536 0.0000

PHE 536 ASP 537 -0.0005

ASP 537 LEU 538 0.0002

LEU 538 THR 539 -0.0001

THR 539 ALA 540 0.0288

ALA 540 THR 541 -0.0001

THR 541 ASN 542 -0.0000

ASN 542 SER 543 -0.0001

SER 543 PHE 544 -0.0001

PHE 544 HIS 545 0.0000

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** ***

CA strain for 2406101858502122271

--- normal mode 30 ---

Should you encounter any unexpected behaviour,
please let us know.

* *