Should you encounter any unexpected behaviour,
please let us know.

* *

CA strain for 2406101858502122271

--- normal mode 27 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 GLU 2 0.0000

GLU 2 LEU 3 -0.0002

LEU 3 LYS 4 -0.0000

LYS 4 ASN 5 0.0000

ASN 5 ILE 6 -0.0003

ILE 6 VAL 7 -0.0001

VAL 7 ASN 8 -0.0005

ASN 8 SER 9 -0.0001

SER 9 TYR 10 0.0001

TYR 10 ASN 11 0.0001

ASN 11 ILE 12 -0.0352

ILE 12 THR 13 0.0003

THR 13 ASN 14 0.0002

ASN 14 ILE 15 0.0000

ILE 15 LEU 16 0.0000

LEU 16 GLY 17 0.0001

GLY 17 TYR 18 -0.0001

TYR 18 LEU 19 -0.0003

LEU 19 ARG 20 0.0002

ARG 20 ARG 21 0.0002

ARG 21 SER 22 0.0003

SER 22 ARG 23 -0.0248

ARG 23 GLN 24 -0.0004

GLN 24 ASP 25 0.0002

ASP 25 MET 26 -0.0001

MET 26 GLU 27 -0.0001

GLU 27 ARG 28 0.0000

ARG 28 GLU 29 0.0002

GLU 29 LYS 30 -0.0001

LYS 30 ARG 31 -0.0002

ARG 31 THR 32 0.0002

THR 32 GLY 33 -0.0002

GLY 33 GLU 34 -0.0098

GLU 34 ASP 35 0.0002

ASP 35 THR 36 0.0001

THR 36 LEU 37 0.0001

LEU 37 THR 38 -0.0001

THR 38 GLU 39 -0.0004

GLU 39 GLN 40 0.0003

GLN 40 LYS 41 0.0001

LYS 41 GLU 42 0.0002

GLU 42 LEU 43 0.0004

LEU 43 MET 44 0.0000

MET 44 ASN 45 -0.0083

ASN 45 LYS 46 -0.0002

LYS 46 ILE 47 0.0002

ILE 47 LEU 48 0.0001

LEU 48 THR 49 0.0003

THR 49 ALA 50 -0.0001

ALA 50 ILE 51 -0.0003

ILE 51 GLU 52 -0.0004

GLU 52 ILE 53 -0.0000

ILE 53 PRO 54 0.0001

PRO 54 TYR 55 0.0000

TYR 55 GLU 56 0.0064

GLU 56 LEU 57 -0.0002

LEU 57 LYS 58 0.0002

LYS 58 MET 59 -0.0000

MET 59 GLU 60 -0.0002

GLU 60 ILE 61 0.0004

ILE 61 GLY 62 0.0002

GLY 62 SER 63 -0.0004

SER 63 GLY 64 0.0002

GLY 64 GLU 65 0.0001

GLU 65 SER 66 -0.0002

SER 66 ILE 67 -0.0007

ILE 67 ASP 68 -0.0003

ASP 68 GLY 69 0.0003

GLY 69 ARG 70 -0.0000

ARG 70 PRO 71 -0.0000

PRO 71 VAL 72 0.0002

VAL 72 PHE 73 -0.0001

PHE 73 LYS 74 -0.0005

LYS 74 GLU 75 0.0004

GLU 75 CYS 76 -0.0001

CYS 76 LEU 77 -0.0004

LEU 77 LYS 78 0.0030

LYS 78 ASP 79 -0.0000

ASP 79 LEU 80 0.0003

LEU 80 GLU 81 -0.0005

GLU 81 GLU 82 0.0003

GLU 82 GLY 83 -0.0000

GLY 83 LYS 84 0.0001

LYS 84 TYR 85 -0.0002

TYR 85 GLN 86 -0.0001

GLN 86 ALA 87 0.0001

ALA 87 ILE 88 0.0000

ILE 88 ALA 89 -0.0075

ALA 89 VAL 90 -0.0002

VAL 90 LYS 91 -0.0002

LYS 91 GLU 92 -0.0003

GLU 92 ILE 93 0.0001

ILE 93 THR 94 -0.0001

THR 94 ARG 95 0.0001

ARG 95 LEU 96 -0.0001

LEU 96 SER 97 -0.0002

SER 97 ARG 98 -0.0001

ARG 98 GLY 99 0.0003

GLY 99 SER 100 -0.0269

SER 100 TYR 101 -0.0001

TYR 101 SER 102 0.0001

SER 102 ASP 103 0.0002

ASP 103 ALA 104 -0.0002

ALA 104 GLY 105 -0.0000

GLY 105 GLN 106 0.0002

GLN 106 ILE 107 0.0000

ILE 107 VAL 108 -0.0000

VAL 108 ASN 109 -0.0000

ASN 109 LEU 110 -0.0000

LEU 110 LEU 111 -0.0001

LEU 111 GLN 112 0.0005

GLN 112 SER 113 -0.0003

SER 113 LYS 114 0.0003

LYS 114 ARG 115 0.0003

ARG 115 LEU 116 0.0003

LEU 116 ILE 117 0.0002

ILE 117 ILE 118 0.0000

ILE 118 ILE 119 0.0000

ILE 119 THR 120 0.0003

THR 120 PRO 121 0.0002

PRO 121 TYR 122 -0.0103

TYR 122 LYS 123 -0.0002

LYS 123 VAL 124 -0.0001

VAL 124 TYR 125 -0.0000

TYR 125 ASP 126 0.0000

ASP 126 PRO 127 0.0002

PRO 127 ARG 128 -0.0001

ARG 128 ASN 129 -0.0004

ASN 129 PRO 130 0.0000

PRO 130 VAL 131 -0.0004

VAL 131 ASP 132 0.0003

ASP 132 MET 133 0.0334

MET 133 ARG 134 -0.0002

ARG 134 GLN 135 -0.0000

GLN 135 ILE 136 0.0000

ILE 136 ARG 137 0.0003

ARG 137 PHE 138 0.0001

PHE 138 GLU 139 -0.0002

GLU 139 LEU 140 -0.0003

LEU 140 PHE 141 0.0000

PHE 141 MET 142 -0.0000

MET 142 ALA 143 -0.0003

ALA 143 ARG 144 -0.0256

ARG 144 GLU 145 0.0002

GLU 145 GLU 146 0.0002

GLU 146 PHE 147 -0.0000

PHE 147 GLU 148 -0.0000

GLU 148 MET 149 0.0004

MET 149 THR 150 -0.0001

THR 150 ARG 151 -0.0003

ARG 151 GLU 152 0.0002

GLU 152 ARG 153 0.0001

ARG 153 MET 154 -0.0002

MET 154 THR 155 -0.0460

THR 155 GLY 156 0.0000

GLY 156 ALA 157 0.0001

ALA 157 LYS 158 -0.0002

LYS 158 TYR 159 -0.0003

TYR 159 THR 160 0.0000

THR 160 TYR 161 -0.0001

TYR 161 ALA 162 -0.0003

ALA 162 ALA 163 -0.0002

ALA 163 GLN 164 0.0003

GLN 164 GLY 165 -0.0000

GLY 165 LYS 166 -0.0442

LYS 166 TRP 167 -0.0001

TRP 167 ILE 168 -0.0000

ILE 168 SER 169 -0.0002

SER 169 GLY 170 -0.0000

GLY 170 LEU 171 -0.0000

LEU 171 ALA 172 0.0001

ALA 172 PRO 173 0.0004

PRO 173 TYR 174 0.0001

TYR 174 GLY 175 -0.0003

GLY 175 TYR 176 0.0003

TYR 176 GLN 177 -0.0270

GLN 177 LEU 178 0.0002

LEU 178 ASN 179 -0.0001

ASN 179 LYS 180 0.0003

LYS 180 LYS 181 -0.0001

LYS 181 THR 182 0.0003

THR 182 SER 183 -0.0002

SER 183 LYS 184 -0.0002

LYS 184 LEU 185 -0.0002

LEU 185 ASP 186 0.0003

ASP 186 PRO 187 -0.0000

PRO 187 VAL 188 -0.0254

VAL 188 GLU 189 -0.0001

GLU 189 ASP 190 -0.0002

ASP 190 GLU 191 -0.0002

GLU 191 ALA 192 0.0000

ALA 192 LYS 193 -0.0001

LYS 193 VAL 194 0.0004

VAL 194 VAL 195 0.0003

VAL 195 GLN 196 0.0001

GLN 196 LEU 197 -0.0000

LEU 197 ILE 198 -0.0000

ILE 198 PHE 199 -0.0072

PHE 199 ASN 200 -0.0002

ASN 200 ILE 201 -0.0001

ILE 201 PHE 202 0.0004

PHE 202 LEU 203 -0.0001

LEU 203 ASN 204 -0.0002

ASN 204 GLY 205 0.0000

GLY 205 LEU 206 0.0000

LEU 206 ASN 207 0.0003

ASN 207 GLY 208 0.0003

GLY 208 LYS 209 0.0004

LYS 209 ASP 210 0.0000

ASP 210 TYR 211 0.0000

TYR 211 SER 212 0.0002

SER 212 TYR 213 0.0003

TYR 213 THR 214 -0.0003

THR 214 ALA 215 -0.0000

ALA 215 ILE 216 0.0001

ILE 216 ALA 217 0.0001

ALA 217 SER 218 0.0002

SER 218 HIS 219 -0.0004

HIS 219 LEU 220 0.0000

LEU 220 THR 221 -0.0013

THR 221 ASN 222 0.0003

ASN 222 LEU 223 -0.0003

LEU 223 GLN 224 -0.0003

GLN 224 ILE 225 0.0001

ILE 225 PRO 226 0.0000

PRO 226 THR 227 0.0000

THR 227 PRO 228 -0.0002

PRO 228 SER 229 -0.0001

SER 229 GLY 230 0.0000

GLY 230 LYS 231 0.0002

LYS 231 LYS 232 -0.0147

LYS 232 ARG 233 -0.0001

ARG 233 TRP 234 0.0002

TRP 234 ASN 235 -0.0004

ASN 235 GLN 236 0.0004

GLN 236 TYR 237 0.0002

TYR 237 THR 238 0.0005

THR 238 ILE 239 0.0004

ILE 239 LYS 240 -0.0002

LYS 240 ALA 241 -0.0003

ALA 241 ILE 242 0.0000

ILE 242 LEU 243 -0.0018

LEU 243 GLN 244 -0.0001

GLN 244 ASN 245 -0.0004

ASN 245 GLU 246 -0.0002

GLU 246 VAL 247 -0.0001

VAL 247 TYR 248 -0.0001

TYR 248 ILE 249 -0.0002

ILE 249 GLY 250 -0.0001

GLY 250 THR 251 0.0001

THR 251 VAL 252 0.0001

VAL 252 LYS 253 0.0000

LYS 253 TYR 254 -0.0564

TYR 254 LYS 255 -0.0002

LYS 255 VAL 256 -0.0001

VAL 256 ARG 257 -0.0001

ARG 257 GLU 258 0.0001

GLU 258 LYS 259 -0.0002

LYS 259 THR 260 0.0004

THR 260 LYS 261 0.0000

LYS 261 ASP 262 0.0005

ASP 262 GLY 263 0.0001

GLY 263 LYS 264 0.0002

LYS 264 ARG 265 0.0082

ARG 265 THR 266 0.0004

THR 266 ILE 267 0.0001

ILE 267 ARG 268 0.0001

ARG 268 PRO 269 0.0003

PRO 269 GLU 270 -0.0001

GLU 270 LYS 271 -0.0002

LYS 271 GLU 272 -0.0002

GLU 272 GLN 273 0.0002

GLN 273 ILE 274 0.0002

ILE 274 VAL 275 0.0000

VAL 275 VAL 276 -0.0561

VAL 276 GLN 277 -0.0000

GLN 277 ASP 278 0.0000

ASP 278 ALA 279 0.0003

ALA 279 HIS 280 -0.0001

HIS 280 ALA 281 -0.0004

ALA 281 PRO 282 0.0001

PRO 282 ILE 283 -0.0001

ILE 283 ILE 284 0.0004

ILE 284 ASP 285 -0.0001

ASP 285 LYS 286 -0.0004

LYS 286 GLU 287 0.0067

GLU 287 GLN 288 -0.0000

GLN 288 PHE 289 -0.0003

PHE 289 GLN 290 -0.0003

GLN 290 GLN 291 0.0000

GLN 291 SER 292 0.0000

SER 292 GLN 293 0.0002

GLN 293 VAL 294 0.0002

VAL 294 LYS 295 0.0001

LYS 295 ILE 296 0.0001

ILE 296 ALA 297 0.0003

ALA 297 ASN 298 0.0507

ASN 298 LYS 299 -0.0002

LYS 299 VAL 300 0.0002

VAL 300 PRO 301 0.0000

PRO 301 LEU 302 0.0002

LEU 302 LEU 303 -0.0002

LEU 303 PRO 304 -0.0002

PRO 304 ASN 305 0.0000

ASN 305 LYS 306 0.0001

LYS 306 ASP 307 -0.0002

ASP 307 GLU 308 -0.0002

GLU 308 PHE 309 -0.0029

PHE 309 GLU 310 -0.0001

GLU 310 LEU 311 -0.0001

LEU 311 SER 312 -0.0000

SER 312 GLU 313 0.0003

GLU 313 LEU 314 0.0001

LEU 314 ALA 315 0.0002

ALA 315 GLY 316 -0.0001

GLY 316 VAL 317 -0.0002

VAL 317 CYS 318 -0.0001

CYS 318 THR 319 -0.0001

THR 319 CYS 320 0.0428

CYS 320 SER 321 -0.0001

SER 321 LYS 322 0.0002

LYS 322 CYS 323 -0.0002

CYS 323 GLY 324 -0.0001

GLY 324 GLU 325 -0.0004

GLU 325 PRO 326 0.0003

PRO 326 LEU 327 -0.0002

LEU 327 SER 328 0.0000

SER 328 LYS 329 0.0001

LYS 329 TYR 330 -0.0000

TYR 330 GLU 331 -0.0031

GLU 331 SER 332 -0.0001

SER 332 LYS 333 0.0001

LYS 333 ARG 334 0.0003

ARG 334 ILE 335 0.0000

ILE 335 ARG 336 -0.0001

ARG 336 LYS 337 0.0001

LYS 337 ASN 338 0.0004

ASN 338 LYS 339 -0.0002

LYS 339 ASP 340 -0.0002

ASP 340 GLY 341 -0.0001

GLY 341 THR 342 -0.0183

THR 342 GLU 343 -0.0002

GLU 343 SER 344 0.0001

SER 344 VAL 345 0.0001

VAL 345 TYR 346 -0.0000

TYR 346 HIS 347 0.0000

HIS 347 VAL 348 0.0001

VAL 348 LYS 349 -0.0003

LYS 349 SER 350 0.0001

SER 350 LEU 351 0.0003

LEU 351 THR 352 0.0001

THR 352 CYS 353 0.0276

CYS 353 LYS 354 0.0001

LYS 354 LYS 355 0.0003

LYS 355 ASN 356 -0.0000

ASN 356 LYS 357 0.0000

LYS 357 CYS 358 0.0001

CYS 358 THR 359 0.0001

THR 359 TYR 360 0.0001

TYR 360 VAL 361 0.0004

VAL 361 ARG 362 0.0001

ARG 362 TYR 363 0.0000

TYR 363 ASN 364 -0.0249

ASN 364 ASP 365 -0.0001

ASP 365 VAL 366 -0.0002

VAL 366 GLU 367 -0.0000

GLU 367 ASN 368 -0.0002

ASN 368 ALA 369 -0.0004

ALA 369 ILE 370 0.0001

ILE 370 LEU 371 0.0000

LEU 371 ASP 372 -0.0001

ASP 372 TYR 373 -0.0003

TYR 373 LEU 374 0.0001

LEU 374 SER 375 0.0239

SER 375 SER 376 0.0002

SER 376 LEU 377 -0.0003

LEU 377 ASN 378 -0.0000

ASN 378 ASP 379 0.0003

ASP 379 LEU 380 0.0001

LEU 380 ASN 381 0.0001

ASN 381 ASP 382 -0.0003

ASP 382 SER 383 0.0000

SER 383 THR 384 -0.0001

THR 384 LEU 385 0.0003

LEU 385 THR 386 0.0079

THR 386 LYS 387 0.0002

LYS 387 HIS 388 -0.0000

HIS 388 ILE 389 -0.0000

ILE 389 ASN 390 -0.0005

ASN 390 SER 391 0.0001

SER 391 MET 392 0.0000

MET 392 LEU 393 -0.0001

LEU 393 SER 394 -0.0002

SER 394 LYS 395 0.0001

LYS 395 TYR 396 0.0000

TYR 396 GLU 397 0.0859

GLU 397 ASP 398 0.0002

ASP 398 ASP 399 -0.0002

ASP 399 ASN 400 0.0002

ASN 400 SER 401 0.0001

SER 401 ASN 402 -0.0002

ASN 402 MET 403 0.0003

MET 403 LYS 404 -0.0000

LYS 404 THR 405 0.0003

THR 405 LYS 406 0.0003

LYS 406 LYS 407 0.0001

LYS 407 GLN 408 -0.0048

GLN 408 MET 409 0.0001

MET 409 SER 410 0.0000

SER 410 GLU 411 0.0002

GLU 411 HIS 412 -0.0000

HIS 412 LEU 413 0.0001

LEU 413 SER 414 -0.0002

SER 414 GLN 415 0.0004

GLN 415 LYS 416 -0.0001

LYS 416 GLU 417 -0.0004

GLU 417 LYS 418 -0.0005

LYS 418 GLU 419 -0.0129

GLU 419 LEU 420 0.0003

LEU 420 LYS 421 -0.0002

LYS 421 ASN 422 -0.0000

ASN 422 LYS 423 -0.0000

LYS 423 GLU 424 0.0002

GLU 424 ASN 425 0.0000

ASN 425 PHE 426 -0.0001

PHE 426 ILE 427 0.0002

ILE 427 PHE 428 0.0002

PHE 428 ASP 429 0.0001

ASP 429 LYS 430 0.0070

LYS 430 TYR 431 0.0000

TYR 431 GLU 432 0.0001

GLU 432 SER 433 0.0000

SER 433 GLY 434 -0.0002

GLY 434 ILE 435 -0.0001

ILE 435 TYR 436 -0.0002

TYR 436 SER 437 0.0002

SER 437 ASP 438 -0.0004

ASP 438 GLU 439 -0.0000

GLU 439 LEU 440 0.0002

LEU 440 PHE 441 0.0008

PHE 441 LEU 442 -0.0001

LEU 442 LYS 443 0.0001

LYS 443 ARG 444 0.0002

ARG 444 LYS 445 0.0003

LYS 445 ALA 446 -0.0002

ALA 446 ALA 447 0.0004

ALA 447 LEU 448 -0.0001

LEU 448 ASP 449 0.0001

ASP 449 GLU 450 0.0003

GLU 450 GLU 451 0.0002

GLU 451 PHE 452 0.0057

PHE 452 LYS 453 0.0001

LYS 453 GLU 454 -0.0001

GLU 454 LEU 455 0.0002

LEU 455 GLN 456 -0.0001

GLN 456 ASN 457 -0.0001

ASN 457 ALA 458 -0.0002

ALA 458 LYS 459 -0.0001

LYS 459 ASN 460 -0.0000

ASN 460 GLU 461 -0.0003

GLU 461 LEU 462 -0.0003

LEU 462 ASN 463 -0.0395

ASN 463 GLY 464 0.0001

GLY 464 LEU 465 -0.0005

LEU 465 GLN 466 0.0001

GLN 466 ASP 467 -0.0001

ASP 467 THR 468 0.0004

THR 468 GLN 469 -0.0002

GLN 469 SER 470 0.0001

SER 470 GLU 471 0.0000

GLU 471 ILE 472 -0.0002

ILE 472 ASP 473 -0.0002

ASP 473 SER 474 -0.0408

SER 474 ASN 475 -0.0003

ASN 475 THR 476 -0.0002

THR 476 VAL 477 -0.0003

VAL 477 ARG 478 -0.0000

ARG 478 ASN 479 0.0000

ASN 479 ASN 480 0.0002

ASN 480 ILE 481 -0.0001

ILE 481 ASN 482 0.0002

ASN 482 LYS 483 -0.0000

LYS 483 ILE 484 -0.0000

ILE 484 ILE 485 -0.0176

ILE 485 ASP 486 -0.0001

ASP 486 GLN 487 -0.0003

GLN 487 TYR 488 -0.0000

TYR 488 HIS 489 0.0001

HIS 489 ILE 490 0.0003

ILE 490 GLU 491 -0.0002

GLU 491 SER 492 -0.0004

SER 492 SER 493 -0.0002

SER 493 SER 494 -0.0002

SER 494 GLU 495 0.0005

GLU 495 LYS 496 -0.0067

LYS 496 LYS 497 0.0000

LYS 497 ASN 498 -0.0001

ASN 498 GLU 499 -0.0001

GLU 499 LEU 500 -0.0002

LEU 500 LEU 501 -0.0001

LEU 501 ARG 502 0.0002

ARG 502 MET 503 0.0002

MET 503 VAL 504 0.0003

VAL 504 LEU 505 -0.0004

LEU 505 LYS 506 -0.0003

LYS 506 ASP 507 0.0756

ASP 507 VAL 508 0.0002

VAL 508 ILE 509 -0.0000

ILE 509 VAL 510 -0.0003

VAL 510 ASN 511 -0.0001

ASN 511 MET 512 -0.0000

MET 512 THR 513 0.0001

THR 513 GLN 514 -0.0001

GLN 514 LYS 515 -0.0001

LYS 515 ARG 516 -0.0001

ARG 516 LYS 517 0.0001

LYS 517 GLY 518 0.0014

GLY 518 PRO 519 -0.0001

PRO 519 ILE 520 0.0002

ILE 520 PRO 521 -0.0003

PRO 521 ALA 522 -0.0001

ALA 522 GLN 523 0.0001

GLN 523 PHE 524 -0.0002

PHE 524 GLU 525 0.0004

GLU 525 ILE 526 -0.0004

ILE 526 THR 527 -0.0001

THR 527 PRO 528 0.0003

PRO 528 ILE 529 0.0121

ILE 529 LEU 530 -0.0001

LEU 530 ARG 531 0.0001

ARG 531 PHE 532 0.0002

PHE 532 ASN 533 -0.0000

ASN 533 PHE 534 -0.0001

PHE 534 ILE 535 0.0003

ILE 535 PHE 536 -0.0000

PHE 536 ASP 537 0.0003

ASP 537 LEU 538 -0.0002

LEU 538 THR 539 -0.0001

THR 539 ALA 540 -0.0178

ALA 540 THR 541 -0.0001

THR 541 ASN 542 0.0002

ASN 542 SER 543 -0.0002

SER 543 PHE 544 -0.0001

PHE 544 HIS 545 -0.0002

HIS 545 MET 1 -0.0274

MET 1 GLU 2 0.0001

GLU 2 LEU 3 -0.0002

LEU 3 LYS 4 -0.0003

LYS 4 ASN 5 0.0002

ASN 5 ILE 6 0.0002

ILE 6 VAL 7 0.0002

VAL 7 ASN 8 -0.0004

ASN 8 SER 9 0.0001

SER 9 TYR 10 -0.0000

TYR 10 ASN 11 -0.0002

ASN 11 ILE 12 0.0301

ILE 12 THR 13 0.0000

THR 13 ASN 14 0.0000

ASN 14 ILE 15 0.0003

ILE 15 LEU 16 -0.0003

LEU 16 GLY 17 0.0002

GLY 17 TYR 18 0.0001

TYR 18 LEU 19 -0.0001

LEU 19 ARG 20 -0.0000

ARG 20 ARG 21 -0.0001

ARG 21 SER 22 0.0002

SER 22 ARG 23 -0.0010

ARG 23 GLN 24 -0.0002

GLN 24 ASP 25 0.0001

ASP 25 MET 26 -0.0002

MET 26 GLU 27 -0.0002

GLU 27 ARG 28 0.0000

ARG 28 GLU 29 -0.0003

GLU 29 LYS 30 0.0002

LYS 30 ARG 31 -0.0002

ARG 31 THR 32 -0.0002

THR 32 GLY 33 -0.0003

GLY 33 GLU 34 -0.0504

GLU 34 ASP 35 0.0002

ASP 35 THR 36 0.0002

THR 36 LEU 37 0.0002

LEU 37 THR 38 0.0002

THR 38 GLU 39 0.0001

GLU 39 GLN 40 0.0004

GLN 40 LYS 41 0.0001

LYS 41 GLU 42 -0.0001

GLU 42 LEU 43 -0.0002

LEU 43 MET 44 0.0001

MET 44 ASN 45 -0.0136

ASN 45 LYS 46 -0.0001

LYS 46 ILE 47 -0.0001

ILE 47 LEU 48 0.0001

LEU 48 THR 49 0.0002

THR 49 ALA 50 0.0004

ALA 50 ILE 51 0.0001

ILE 51 GLU 52 -0.0002

GLU 52 ILE 53 -0.0000

ILE 53 PRO 54 0.0001

PRO 54 TYR 55 -0.0005

TYR 55 GLU 56 -0.0461

GLU 56 LEU 57 0.0001

LEU 57 LYS 58 -0.0002

LYS 58 MET 59 0.0000

MET 59 GLU 60 0.0000

GLU 60 ILE 61 -0.0001

ILE 61 GLY 62 0.0000

GLY 62 SER 63 0.0000

SER 63 GLY 64 0.0002

GLY 64 GLU 65 -0.0000

GLU 65 SER 66 -0.0004

SER 66 ILE 67 -0.0232

ILE 67 ASP 68 0.0003

ASP 68 GLY 69 -0.0001

GLY 69 ARG 70 -0.0003

ARG 70 PRO 71 0.0004

PRO 71 VAL 72 -0.0002

VAL 72 PHE 73 0.0004

PHE 73 LYS 74 -0.0004

LYS 74 GLU 75 -0.0003

GLU 75 CYS 76 0.0002

CYS 76 LEU 77 -0.0002

LEU 77 LYS 78 -0.0064

LYS 78 ASP 79 -0.0002

ASP 79 LEU 80 -0.0002

LEU 80 GLU 81 -0.0002

GLU 81 GLU 82 -0.0000

GLU 82 GLY 83 -0.0000

GLY 83 LYS 84 0.0002

LYS 84 TYR 85 0.0000

TYR 85 GLN 86 -0.0000

GLN 86 ALA 87 0.0002

ALA 87 ILE 88 -0.0001

ILE 88 ALA 89 0.0004

ALA 89 VAL 90 0.0001

VAL 90 LYS 91 0.0003

LYS 91 GLU 92 -0.0003

GLU 92 ILE 93 0.0002

ILE 93 THR 94 -0.0000

THR 94 ARG 95 0.0001

ARG 95 LEU 96 0.0001

LEU 96 SER 97 -0.0003

SER 97 ARG 98 -0.0001

ARG 98 GLY 99 0.0002

GLY 99 SER 100 -0.0365

SER 100 TYR 101 0.0001

TYR 101 SER 102 0.0001

SER 102 ASP 103 0.0000

ASP 103 ALA 104 0.0002

ALA 104 GLY 105 0.0002

GLY 105 GLN 106 0.0001

GLN 106 ILE 107 -0.0001

ILE 107 VAL 108 0.0000

VAL 108 ASN 109 -0.0003

ASN 109 LEU 110 0.0001

LEU 110 LEU 111 -0.0021

LEU 111 GLN 112 0.0002

GLN 112 SER 113 -0.0000

SER 113 LYS 114 -0.0002

LYS 114 ARG 115 -0.0001

ARG 115 LEU 116 0.0001

LEU 116 ILE 117 -0.0004

ILE 117 ILE 118 -0.0002

ILE 118 ILE 119 0.0000

ILE 119 THR 120 0.0002

THR 120 PRO 121 -0.0000

PRO 121 TYR 122 -0.0199

TYR 122 LYS 123 -0.0000

LYS 123 VAL 124 -0.0004

VAL 124 TYR 125 0.0001

TYR 125 ASP 126 -0.0002

ASP 126 PRO 127 -0.0001

PRO 127 ARG 128 0.0002

ARG 128 ASN 129 0.0003

ASN 129 PRO 130 0.0002

PRO 130 VAL 131 -0.0001

VAL 131 ASP 132 0.0003

ASP 132 MET 133 0.0158

MET 133 ARG 134 -0.0000

ARG 134 GLN 135 -0.0001

GLN 135 ILE 136 0.0001

ILE 136 ARG 137 0.0002

ARG 137 PHE 138 0.0004

PHE 138 GLU 139 0.0001

GLU 139 LEU 140 -0.0001

LEU 140 PHE 141 0.0001

PHE 141 MET 142 -0.0001

MET 142 ALA 143 0.0001

ALA 143 ARG 144 -0.0292

ARG 144 GLU 145 0.0001

GLU 145 GLU 146 -0.0001

GLU 146 PHE 147 -0.0000

PHE 147 GLU 148 0.0003

GLU 148 MET 149 0.0003

MET 149 THR 150 0.0002

THR 150 ARG 151 -0.0002

ARG 151 GLU 152 -0.0001

GLU 152 ARG 153 -0.0001

ARG 153 MET 154 -0.0000

MET 154 THR 155 -0.0323

THR 155 GLY 156 0.0002

GLY 156 ALA 157 -0.0003

ALA 157 LYS 158 0.0005

LYS 158 TYR 159 0.0002

TYR 159 THR 160 0.0001

THR 160 TYR 161 0.0001

TYR 161 ALA 162 0.0004

ALA 162 ALA 163 0.0000

ALA 163 GLN 164 0.0001

GLN 164 GLY 165 0.0003

GLY 165 LYS 166 0.0440

LYS 166 TRP 167 0.0001

TRP 167 ILE 168 -0.0005

ILE 168 SER 169 0.0002

SER 169 GLY 170 -0.0001

GLY 170 LEU 171 0.0001

LEU 171 ALA 172 0.0001

ALA 172 PRO 173 -0.0003

PRO 173 TYR 174 -0.0000

TYR 174 GLY 175 -0.0003

GLY 175 TYR 176 -0.0001

TYR 176 GLN 177 0.0247

GLN 177 LEU 178 0.0001

LEU 178 ASN 179 -0.0000

ASN 179 LYS 180 -0.0005

LYS 180 LYS 181 0.0001

LYS 181 THR 182 -0.0000

THR 182 SER 183 -0.0000

SER 183 LYS 184 0.0002

LYS 184 LEU 185 -0.0004

LEU 185 ASP 186 0.0001

ASP 186 PRO 187 0.0002

PRO 187 VAL 188 0.0120

VAL 188 GLU 189 0.0000

GLU 189 ASP 190 -0.0003

ASP 190 GLU 191 0.0004

GLU 191 ALA 192 0.0001

ALA 192 LYS 193 -0.0001

LYS 193 VAL 194 0.0001

VAL 194 VAL 195 -0.0001

VAL 195 GLN 196 0.0004

GLN 196 LEU 197 0.0001

LEU 197 ILE 198 0.0002

ILE 198 PHE 199 0.0027

PHE 199 ASN 200 0.0000

ASN 200 ILE 201 -0.0002

ILE 201 PHE 202 0.0002

PHE 202 LEU 203 0.0003

LEU 203 ASN 204 -0.0000

ASN 204 GLY 205 0.0001

GLY 205 LEU 206 0.0000

LEU 206 ASN 207 0.0004

ASN 207 GLY 208 -0.0001

GLY 208 LYS 209 0.0001

LYS 209 ASP 210 0.0262

ASP 210 TYR 211 -0.0000

TYR 211 SER 212 0.0003

SER 212 TYR 213 -0.0004

TYR 213 THR 214 0.0001

THR 214 ALA 215 0.0002

ALA 215 ILE 216 0.0001

ILE 216 ALA 217 -0.0001

ALA 217 SER 218 -0.0003

SER 218 HIS 219 -0.0001

HIS 219 LEU 220 -0.0002

LEU 220 THR 221 -0.0048

THR 221 ASN 222 0.0000

ASN 222 LEU 223 0.0002

LEU 223 GLN 224 -0.0000

GLN 224 ILE 225 0.0002

ILE 225 PRO 226 0.0002

PRO 226 THR 227 0.0000

THR 227 PRO 228 0.0004

PRO 228 SER 229 -0.0001

SER 229 GLY 230 -0.0003

GLY 230 LYS 231 -0.0001

LYS 231 LYS 232 0.0427

LYS 232 ARG 233 0.0000

ARG 233 TRP 234 -0.0001

TRP 234 ASN 235 0.0002

ASN 235 GLN 236 -0.0002

GLN 236 TYR 237 0.0001

TYR 237 THR 238 0.0002

THR 238 ILE 239 -0.0001

ILE 239 LYS 240 0.0001

LYS 240 ALA 241 0.0001

ALA 241 ILE 242 -0.0001

ILE 242 LEU 243 -0.0187

LEU 243 GLN 244 0.0001

GLN 244 ASN 245 0.0001

ASN 245 GLU 246 0.0001

GLU 246 VAL 247 -0.0002

VAL 247 TYR 248 0.0001

TYR 248 ILE 249 -0.0003

ILE 249 GLY 250 0.0001

GLY 250 THR 251 0.0004

THR 251 VAL 252 -0.0002

VAL 252 LYS 253 -0.0003

LYS 253 TYR 254 0.1334

TYR 254 LYS 255 -0.0003

LYS 255 VAL 256 -0.0002

VAL 256 ARG 257 0.0003

ARG 257 GLU 258 -0.0000

GLU 258 LYS 259 -0.0001

LYS 259 THR 260 -0.0001

THR 260 LYS 261 0.0001

LYS 261 ASP 262 0.0001

ASP 262 GLY 263 0.0001

GLY 263 LYS 264 0.0002

LYS 264 ARG 265 0.0092

ARG 265 THR 266 0.0001

THR 266 ILE 267 -0.0001

ILE 267 ARG 268 0.0000

ARG 268 PRO 269 0.0001

PRO 269 GLU 270 0.0002

GLU 270 LYS 271 0.0001

LYS 271 GLU 272 -0.0003

GLU 272 GLN 273 -0.0001

GLN 273 ILE 274 0.0002

ILE 274 VAL 275 0.0001

VAL 275 VAL 276 0.1935

VAL 276 GLN 277 0.0004

GLN 277 ASP 278 -0.0000

ASP 278 ALA 279 -0.0000

ALA 279 HIS 280 0.0002

HIS 280 ALA 281 -0.0004

ALA 281 PRO 282 -0.0003

PRO 282 ILE 283 0.0002

ILE 283 ILE 284 0.0001

ILE 284 ASP 285 -0.0000

ASP 285 LYS 286 -0.0001

LYS 286 GLU 287 -0.0239

GLU 287 GLN 288 -0.0002

GLN 288 PHE 289 0.0000

PHE 289 GLN 290 -0.0000

GLN 290 GLN 291 -0.0001

GLN 291 SER 292 0.0004

SER 292 GLN 293 -0.0003

GLN 293 VAL 294 -0.0000

VAL 294 LYS 295 -0.0001

LYS 295 ILE 296 0.0002

ILE 296 ALA 297 0.0000

ALA 297 ASN 298 -0.1744

ASN 298 LYS 299 -0.0001

LYS 299 VAL 300 -0.0004

VAL 300 PRO 301 -0.0000

PRO 301 LEU 302 0.0002

LEU 302 LEU 303 -0.0002

LEU 303 PRO 304 0.0001

PRO 304 ASN 305 0.0001

ASN 305 LYS 306 -0.0005

LYS 306 ASP 307 0.0001

ASP 307 GLU 308 -0.0003

GLU 308 PHE 309 -0.2195

PHE 309 GLU 310 0.0001

GLU 310 LEU 311 -0.0002

LEU 311 SER 312 -0.0002

SER 312 GLU 313 -0.0000

GLU 313 LEU 314 -0.0000

LEU 314 ALA 315 -0.0001

ALA 315 GLY 316 0.0002

GLY 316 VAL 317 -0.0003

VAL 317 CYS 318 0.0000

CYS 318 THR 319 0.0001

THR 319 CYS 320 0.0732

CYS 320 SER 321 -0.0000

SER 321 LYS 322 -0.0002

LYS 322 CYS 323 0.0004

CYS 323 GLY 324 -0.0003

GLY 324 GLU 325 -0.0002

GLU 325 PRO 326 -0.0001

PRO 326 LEU 327 0.0004

LEU 327 SER 328 0.0000

SER 328 LYS 329 0.0003

LYS 329 TYR 330 -0.0001

TYR 330 GLU 331 0.0204

GLU 331 SER 332 -0.0002

SER 332 LYS 333 0.0003

LYS 333 ARG 334 0.0001

ARG 334 ILE 335 -0.0002

ILE 335 ARG 336 0.0002

ARG 336 LYS 337 -0.0003

LYS 337 ASN 338 0.0001

ASN 338 LYS 339 0.0001

LYS 339 ASP 340 0.0004

ASP 340 GLY 341 0.0001

GLY 341 THR 342 -0.0722

THR 342 GLU 343 0.0001

GLU 343 SER 344 0.0002

SER 344 VAL 345 -0.0004

VAL 345 TYR 346 -0.0001

TYR 346 HIS 347 0.0000

HIS 347 VAL 348 0.0002

VAL 348 LYS 349 0.0000

LYS 349 SER 350 0.0005

SER 350 LEU 351 -0.0003

LEU 351 THR 352 0.0000

THR 352 CYS 353 0.1297

CYS 353 LYS 354 0.0001

LYS 354 LYS 355 -0.0001

LYS 355 ASN 356 -0.0004

ASN 356 LYS 357 0.0002

LYS 357 CYS 358 -0.0000

CYS 358 THR 359 -0.0000

THR 359 TYR 360 0.0000

TYR 360 VAL 361 0.0000

VAL 361 ARG 362 -0.0003

ARG 362 TYR 363 -0.0004

TYR 363 ASN 364 -0.0283

ASN 364 ASP 365 0.0003

ASP 365 VAL 366 0.0003

VAL 366 GLU 367 0.0001

GLU 367 ASN 368 -0.0001

ASN 368 ALA 369 0.0004

ALA 369 ILE 370 -0.0001

ILE 370 LEU 371 0.0000

LEU 371 ASP 372 -0.0001

ASP 372 TYR 373 -0.0003

TYR 373 LEU 374 -0.0001

LEU 374 SER 375 0.0444

SER 375 SER 376 -0.0001

SER 376 LEU 377 -0.0001

LEU 377 ASN 378 -0.0000

ASN 378 ASP 379 -0.0003

ASP 379 LEU 380 0.0003

LEU 380 ASN 381 -0.0001

ASN 381 ASP 382 0.0002

ASP 382 SER 383 0.0002

SER 383 THR 384 -0.0001

THR 384 LEU 385 -0.0002

LEU 385 THR 386 -0.0135

THR 386 LYS 387 0.0002

LYS 387 HIS 388 0.0001

HIS 388 ILE 389 0.0001

ILE 389 ASN 390 -0.0002

ASN 390 SER 391 0.0001

SER 391 MET 392 0.0001

MET 392 LEU 393 -0.0000

LEU 393 SER 394 -0.0002

SER 394 LYS 395 -0.0003

LYS 395 TYR 396 -0.0002

TYR 396 GLU 397 0.1664

GLU 397 ASP 398 0.0002

ASP 398 ASP 399 0.0002

ASP 399 ASN 400 -0.0000

ASN 400 SER 401 -0.0001

SER 401 ASN 402 -0.0002

ASN 402 MET 403 0.0001

MET 403 LYS 404 -0.0001

LYS 404 THR 405 -0.0004

THR 405 LYS 406 -0.0003

LYS 406 LYS 407 0.0002

LYS 407 GLN 408 0.0165

GLN 408 MET 409 -0.0000

MET 409 SER 410 -0.0000

SER 410 GLU 411 0.0001

GLU 411 HIS 412 0.0001

HIS 412 LEU 413 -0.0003

LEU 413 SER 414 0.0003

SER 414 GLN 415 0.0003

GLN 415 LYS 416 -0.0002

LYS 416 GLU 417 -0.0001

GLU 417 LYS 418 -0.0002

LYS 418 GLU 419 -0.0080

GLU 419 LEU 420 -0.0000

LEU 420 LYS 421 -0.0000

LYS 421 ASN 422 -0.0001

ASN 422 LYS 423 -0.0001

LYS 423 GLU 424 -0.0004

GLU 424 ASN 425 -0.0001

ASN 425 PHE 426 -0.0003

PHE 426 ILE 427 -0.0003

ILE 427 PHE 428 0.0000

PHE 428 ASP 429 0.0003

ASP 429 LYS 430 -0.0003

LYS 430 TYR 431 0.0003

TYR 431 GLU 432 -0.0002

GLU 432 SER 433 -0.0001

SER 433 GLY 434 -0.0002

GLY 434 ILE 435 0.0002

ILE 435 TYR 436 0.0001

TYR 436 SER 437 -0.0001

SER 437 ASP 438 0.0003

ASP 438 GLU 439 -0.0000

GLU 439 LEU 440 -0.0001

LEU 440 PHE 441 0.0217

PHE 441 LEU 442 -0.0002

LEU 442 LYS 443 -0.0003

LYS 443 ARG 444 0.0002

ARG 444 LYS 445 0.0005

LYS 445 ALA 446 0.0005

ALA 446 ALA 447 -0.0000

ALA 447 LEU 448 -0.0000

LEU 448 ASP 449 -0.0004

ASP 449 GLU 450 -0.0001

GLU 450 GLU 451 -0.0000

GLU 451 PHE 452 0.0201

PHE 452 LYS 453 -0.0004

LYS 453 GLU 454 -0.0003

GLU 454 LEU 455 -0.0000

LEU 455 GLN 456 -0.0005

GLN 456 ASN 457 -0.0002

ASN 457 ALA 458 -0.0001

ALA 458 LYS 459 0.0001

LYS 459 ASN 460 0.0002

ASN 460 GLU 461 0.0004

GLU 461 LEU 462 0.0004

LEU 462 ASN 463 0.0415

ASN 463 GLY 464 0.0001

GLY 464 LEU 465 0.0000

LEU 465 GLN 466 0.0001

GLN 466 ASP 467 0.0000

ASP 467 THR 468 0.0003

THR 468 GLN 469 -0.0001

GLN 469 SER 470 -0.0002

SER 470 GLU 471 0.0001

GLU 471 ILE 472 0.0002

ILE 472 ASP 473 0.0002

ASP 473 SER 474 -0.1370

SER 474 ASN 475 -0.0002

ASN 475 THR 476 0.0001

THR 476 VAL 477 -0.0003

VAL 477 ARG 478 0.0002

ARG 478 ASN 479 -0.0001

ASN 479 ASN 480 0.0002

ASN 480 ILE 481 0.0000

ILE 481 ASN 482 -0.0001

ASN 482 LYS 483 0.0001

LYS 483 ILE 484 0.0001

ILE 484 ILE 485 -0.0480

ILE 485 ASP 486 0.0001

ASP 486 GLN 487 -0.0003

GLN 487 TYR 488 -0.0000

TYR 488 HIS 489 0.0001

HIS 489 ILE 490 0.0002

ILE 490 GLU 491 -0.0001

GLU 491 SER 492 -0.0000

SER 492 SER 493 -0.0002

SER 493 SER 494 0.0004

SER 494 GLU 495 0.0005

GLU 495 LYS 496 0.0076

LYS 496 LYS 497 -0.0000

LYS 497 ASN 498 0.0003

ASN 498 GLU 499 0.0001

GLU 499 LEU 500 -0.0001

LEU 500 LEU 501 -0.0003

LEU 501 ARG 502 0.0002

ARG 502 MET 503 -0.0004

MET 503 VAL 504 -0.0002

VAL 504 LEU 505 0.0001

LEU 505 LYS 506 -0.0002

LYS 506 ASP 507 0.1515

ASP 507 VAL 508 -0.0001

VAL 508 ILE 509 0.0000

ILE 509 VAL 510 0.0002

VAL 510 ASN 511 -0.0001

ASN 511 MET 512 0.0005

MET 512 THR 513 -0.0002

THR 513 GLN 514 -0.0004

GLN 514 LYS 515 -0.0001

LYS 515 ARG 516 0.0003

ARG 516 LYS 517 0.0001

LYS 517 GLY 518 -0.0065

GLY 518 PRO 519 -0.0001

PRO 519 ILE 520 0.0000

ILE 520 PRO 521 0.0001

PRO 521 ALA 522 -0.0004

ALA 522 GLN 523 0.0001

GLN 523 PHE 524 0.0002

PHE 524 GLU 525 -0.0000

GLU 525 ILE 526 -0.0003

ILE 526 THR 527 -0.0001

THR 527 PRO 528 0.0001

PRO 528 ILE 529 0.0517

ILE 529 LEU 530 0.0001

LEU 530 ARG 531 0.0004

ARG 531 PHE 532 0.0001

PHE 532 ASN 533 0.0005

ASN 533 PHE 534 0.0001

PHE 534 ILE 535 0.0001

ILE 535 PHE 536 0.0005

PHE 536 ASP 537 0.0000

ASP 537 LEU 538 -0.0000

LEU 538 THR 539 0.0001

THR 539 ALA 540 -0.0387

ALA 540 THR 541 -0.0000

THR 541 ASN 542 0.0002

ASN 542 SER 543 -0.0000

SER 543 PHE 544 0.0003

PHE 544 HIS 545 -0.0002

HIS 545 MET 1 -0.0575

MET 1 GLU 2 0.0003

GLU 2 LEU 3 -0.0000

LEU 3 LYS 4 0.0002

LYS 4 ASN 5 0.0002

ASN 5 ILE 6 -0.0002

ILE 6 VAL 7 -0.0002

VAL 7 ASN 8 -0.0003

ASN 8 SER 9 0.0002

SER 9 TYR 10 0.0002

TYR 10 ASN 11 0.0002

ASN 11 ILE 12 0.0336

ILE 12 THR 13 0.0001

THR 13 ASN 14 -0.0001

ASN 14 ILE 15 0.0002

ILE 15 LEU 16 -0.0001

LEU 16 GLY 17 -0.0000

GLY 17 TYR 18 -0.0000

TYR 18 LEU 19 -0.0002

LEU 19 ARG 20 0.0003

ARG 20 ARG 21 -0.0000

ARG 21 SER 22 -0.0001

SER 22 ARG 23 0.0363

ARG 23 GLN 24 -0.0004

GLN 24 ASP 25 -0.0001

ASP 25 MET 26 -0.0000

MET 26 GLU 27 0.0001

GLU 27 ARG 28 0.0002

ARG 28 GLU 29 0.0001

GLU 29 LYS 30 0.0002

LYS 30 ARG 31 0.0004

ARG 31 THR 32 -0.0001

THR 32 GLY 33 -0.0002

GLY 33 GLU 34 0.0037

GLU 34 ASP 35 -0.0003

ASP 35 THR 36 -0.0000

THR 36 LEU 37 -0.0000

LEU 37 THR 38 -0.0001

THR 38 GLU 39 -0.0002

GLU 39 GLN 40 0.0000

GLN 40 LYS 41 0.0003

LYS 41 GLU 42 0.0001

GLU 42 LEU 43 -0.0002

LEU 43 MET 44 -0.0001

MET 44 ASN 45 0.0061

ASN 45 LYS 46 -0.0004

LYS 46 ILE 47 -0.0000

ILE 47 LEU 48 -0.0002

LEU 48 THR 49 0.0001

THR 49 ALA 50 0.0000

ALA 50 ILE 51 0.0000

ILE 51 GLU 52 -0.0003

GLU 52 ILE 53 -0.0002

ILE 53 PRO 54 0.0005

PRO 54 TYR 55 -0.0002

TYR 55 GLU 56 0.0014

GLU 56 LEU 57 -0.0001

LEU 57 LYS 58 -0.0002

LYS 58 MET 59 0.0003

MET 59 GLU 60 -0.0002

GLU 60 ILE 61 0.0002

ILE 61 GLY 62 -0.0001

GLY 62 SER 63 -0.0001

SER 63 GLY 64 -0.0000

GLY 64 GLU 65 0.0001

GLU 65 SER 66 0.0001

SER 66 ILE 67 0.0085

ILE 67 ASP 68 0.0001

ASP 68 GLY 69 -0.0000

GLY 69 ARG 70 -0.0001

ARG 70 PRO 71 -0.0003

PRO 71 VAL 72 -0.0001

VAL 72 PHE 73 0.0001

PHE 73 LYS 74 -0.0001

LYS 74 GLU 75 0.0001

GLU 75 CYS 76 -0.0002

CYS 76 LEU 77 0.0001

LEU 77 LYS 78 -0.0050

LYS 78 ASP 79 -0.0000

ASP 79 LEU 80 0.0000

LEU 80 GLU 81 -0.0000

GLU 81 GLU 82 0.0001

GLU 82 GLY 83 -0.0000

GLY 83 LYS 84 0.0001

LYS 84 TYR 85 0.0000

TYR 85 GLN 86 -0.0005

GLN 86 ALA 87 0.0000

ALA 87 ILE 88 0.0001

ILE 88 ALA 89 0.0093

ALA 89 VAL 90 0.0002

VAL 90 LYS 91 0.0000

LYS 91 GLU 92 0.0002

GLU 92 ILE 93 -0.0003

ILE 93 THR 94 -0.0000

THR 94 ARG 95 0.0002

ARG 95 LEU 96 -0.0000

LEU 96 SER 97 -0.0005

SER 97 ARG 98 -0.0002

ARG 98 GLY 99 0.0001

GLY 99 SER 100 0.0236

SER 100 TYR 101 0.0001

TYR 101 SER 102 -0.0002

SER 102 ASP 103 0.0005

ASP 103 ALA 104 -0.0000

ALA 104 GLY 105 -0.0001

GLY 105 GLN 106 0.0003

GLN 106 ILE 107 0.0002

ILE 107 VAL 108 0.0001

VAL 108 ASN 109 -0.0003

ASN 109 LEU 110 0.0003

LEU 110 LEU 111 -0.0001

LEU 111 GLN 112 0.0000

GLN 112 SER 113 0.0002

SER 113 LYS 114 -0.0001

LYS 114 ARG 115 0.0003

ARG 115 LEU 116 0.0006

LEU 116 ILE 117 -0.0000

ILE 117 ILE 118 -0.0002

ILE 118 ILE 119 0.0002

ILE 119 THR 120 0.0001

THR 120 PRO 121 0.0003

PRO 121 TYR 122 0.0147

TYR 122 LYS 123 0.0001

LYS 123 VAL 124 0.0000

VAL 124 TYR 125 0.0005

TYR 125 ASP 126 -0.0000

ASP 126 PRO 127 -0.0002

PRO 127 ARG 128 0.0001

ARG 128 ASN 129 -0.0004

ASN 129 PRO 130 -0.0001

PRO 130 VAL 131 0.0001

VAL 131 ASP 132 0.0000

ASP 132 MET 133 -0.0359

MET 133 ARG 134 -0.0003

ARG 134 GLN 135 -0.0001

GLN 135 ILE 136 0.0003

ILE 136 ARG 137 -0.0000

ARG 137 PHE 138 0.0000

PHE 138 GLU 139 0.0002

GLU 139 LEU 140 0.0005

LEU 140 PHE 141 -0.0003

PHE 141 MET 142 -0.0001

MET 142 ALA 143 -0.0002

ALA 143 ARG 144 0.0210

ARG 144 GLU 145 0.0003

GLU 145 GLU 146 0.0001

GLU 146 PHE 147 -0.0001

PHE 147 GLU 148 -0.0000

GLU 148 MET 149 -0.0004

MET 149 THR 150 -0.0003

THR 150 ARG 151 -0.0001

ARG 151 GLU 152 -0.0001

GLU 152 ARG 153 -0.0002

ARG 153 MET 154 0.0003

MET 154 THR 155 -0.0052

THR 155 GLY 156 -0.0004

GLY 156 ALA 157 0.0001

ALA 157 LYS 158 0.0003

LYS 158 TYR 159 -0.0002

TYR 159 THR 160 0.0002

THR 160 TYR 161 -0.0001

TYR 161 ALA 162 0.0002

ALA 162 ALA 163 0.0001

ALA 163 GLN 164 0.0002

GLN 164 GLY 165 -0.0000

GLY 165 LYS 166 0.0315

LYS 166 TRP 167 0.0001

TRP 167 ILE 168 0.0002

ILE 168 SER 169 0.0002

SER 169 GLY 170 -0.0004

GLY 170 LEU 171 -0.0000

LEU 171 ALA 172 -0.0003

ALA 172 PRO 173 0.0001

PRO 173 TYR 174 -0.0001

TYR 174 GLY 175 0.0000

GLY 175 TYR 176 0.0003

TYR 176 GLN 177 0.0102

GLN 177 LEU 178 -0.0003

LEU 178 ASN 179 -0.0001

ASN 179 LYS 180 0.0000

LYS 180 LYS 181 0.0004

LYS 181 THR 182 0.0001

THR 182 SER 183 0.0005

SER 183 LYS 184 -0.0001

LYS 184 LEU 185 0.0002

LEU 185 ASP 186 0.0002

ASP 186 PRO 187 -0.0001

PRO 187 VAL 188 0.0183

VAL 188 GLU 189 -0.0000

GLU 189 ASP 190 0.0005

ASP 190 GLU 191 0.0002

GLU 191 ALA 192 -0.0001

ALA 192 LYS 193 -0.0002

LYS 193 VAL 194 0.0000

VAL 194 VAL 195 -0.0000

VAL 195 GLN 196 0.0001

GLN 196 LEU 197 -0.0001

LEU 197 ILE 198 -0.0003

ILE 198 PHE 199 0.0121

PHE 199 ASN 200 0.0003

ASN 200 ILE 201 -0.0001

ILE 201 PHE 202 0.0001

PHE 202 LEU 203 -0.0002

LEU 203 ASN 204 -0.0001

ASN 204 GLY 205 -0.0002

GLY 205 LEU 206 0.0002

LEU 206 ASN 207 -0.0000

ASN 207 GLY 208 0.0002

GLY 208 LYS 209 0.0001

LYS 209 ASP 210 -0.0045

ASP 210 TYR 211 -0.0002

TYR 211 SER 212 -0.0000

SER 212 TYR 213 -0.0003

TYR 213 THR 214 0.0001

THR 214 ALA 215 -0.0005

ALA 215 ILE 216 0.0002

ILE 216 ALA 217 0.0002

ALA 217 SER 218 -0.0004

SER 218 HIS 219 -0.0001

HIS 219 LEU 220 0.0001

LEU 220 THR 221 0.0004

THR 221 ASN 222 0.0003

ASN 222 LEU 223 0.0003

LEU 223 GLN 224 0.0000

GLN 224 ILE 225 -0.0004

ILE 225 PRO 226 0.0001

PRO 226 THR 227 -0.0002

THR 227 PRO 228 -0.0000

PRO 228 SER 229 0.0003

SER 229 GLY 230 -0.0003

GLY 230 LYS 231 0.0003

LYS 231 LYS 232 0.0044

LYS 232 ARG 233 -0.0003

ARG 233 TRP 234 -0.0001

TRP 234 ASN 235 0.0001

ASN 235 GLN 236 0.0002

GLN 236 TYR 237 -0.0001

TYR 237 THR 238 0.0002

THR 238 ILE 239 -0.0001

ILE 239 LYS 240 -0.0002

LYS 240 ALA 241 0.0001

ALA 241 ILE 242 -0.0001

ILE 242 LEU 243 0.0026

LEU 243 GLN 244 -0.0001

GLN 244 ASN 245 0.0002

ASN 245 GLU 246 -0.0001

GLU 246 VAL 247 -0.0001

VAL 247 TYR 248 0.0002

TYR 248 ILE 249 -0.0001

ILE 249 GLY 250 -0.0003

GLY 250 THR 251 0.0001

THR 251 VAL 252 0.0002

VAL 252 LYS 253 -0.0002

LYS 253 TYR 254 -0.0388

TYR 254 LYS 255 -0.0004

LYS 255 VAL 256 -0.0001

VAL 256 ARG 257 0.0002

ARG 257 GLU 258 -0.0003

GLU 258 LYS 259 0.0004

LYS 259 THR 260 -0.0002

THR 260 LYS 261 0.0002

LYS 261 ASP 262 0.0000

ASP 262 GLY 263 0.0001

GLY 263 LYS 264 -0.0001

LYS 264 ARG 265 -0.0072

ARG 265 THR 266 0.0002

THR 266 ILE 267 0.0002

ILE 267 ARG 268 -0.0000

ARG 268 PRO 269 -0.0000

PRO 269 GLU 270 0.0001

GLU 270 LYS 271 -0.0002

LYS 271 GLU 272 -0.0003

GLU 272 GLN 273 -0.0004

GLN 273 ILE 274 0.0005

ILE 274 VAL 275 0.0003

VAL 275 VAL 276 0.0395

VAL 276 GLN 277 -0.0000

GLN 277 ASP 278 -0.0001

ASP 278 ALA 279 0.0004

ALA 279 HIS 280 -0.0003

HIS 280 ALA 281 0.0000

ALA 281 PRO 282 0.0001

PRO 282 ILE 283 0.0000

ILE 283 ILE 284 0.0002

ILE 284 ASP 285 -0.0003

ASP 285 LYS 286 0.0005

LYS 286 GLU 287 -0.0156

GLU 287 GLN 288 -0.0002

GLN 288 PHE 289 -0.0001

PHE 289 GLN 290 0.0002

GLN 290 GLN 291 -0.0003

GLN 291 SER 292 -0.0001

SER 292 GLN 293 0.0003

GLN 293 VAL 294 0.0001

VAL 294 LYS 295 0.0001

LYS 295 ILE 296 0.0001

ILE 296 ALA 297 0.0003

ALA 297 ASN 298 -0.0738

ASN 298 LYS 299 0.0001

LYS 299 VAL 300 -0.0002

VAL 300 PRO 301 0.0003

PRO 301 LEU 302 -0.0005

LEU 302 LEU 303 0.0002

LEU 303 PRO 304 0.0003

PRO 304 ASN 305 -0.0003

ASN 305 LYS 306 0.0003

LYS 306 ASP 307 -0.0002

ASP 307 GLU 308 -0.0004

GLU 308 PHE 309 0.0057

PHE 309 GLU 310 0.0000

GLU 310 LEU 311 0.0001

LEU 311 SER 312 -0.0003

SER 312 GLU 313 0.0000

GLU 313 LEU 314 -0.0001

LEU 314 ALA 315 0.0002

ALA 315 GLY 316 0.0002

GLY 316 VAL 317 0.0002

VAL 317 CYS 318 -0.0001

CYS 318 THR 319 -0.0001

THR 319 CYS 320 -0.0094

CYS 320 SER 321 0.0000

SER 321 LYS 322 -0.0001

LYS 322 CYS 323 -0.0000

CYS 323 GLY 324 0.0000

GLY 324 GLU 325 0.0001

GLU 325 PRO 326 0.0003

PRO 326 LEU 327 0.0001

LEU 327 SER 328 0.0002

SER 328 LYS 329 0.0003

LYS 329 TYR 330 -0.0003

TYR 330 GLU 331 0.0064

GLU 331 SER 332 -0.0003

SER 332 LYS 333 0.0002

LYS 333 ARG 334 -0.0004

ARG 334 ILE 335 0.0001

ILE 335 ARG 336 -0.0000

ARG 336 LYS 337 -0.0002

LYS 337 ASN 338 0.0001

ASN 338 LYS 339 -0.0005

LYS 339 ASP 340 -0.0000

ASP 340 GLY 341 -0.0001

GLY 341 THR 342 -0.0099

THR 342 GLU 343 -0.0002

GLU 343 SER 344 0.0000

SER 344 VAL 345 0.0001

VAL 345 TYR 346 0.0001

TYR 346 HIS 347 0.0000

HIS 347 VAL 348 -0.0004

VAL 348 LYS 349 0.0002

LYS 349 SER 350 0.0001

SER 350 LEU 351 -0.0001

LEU 351 THR 352 -0.0004

THR 352 CYS 353 0.0074

CYS 353 LYS 354 0.0002

LYS 354 LYS 355 0.0002

LYS 355 ASN 356 -0.0002

ASN 356 LYS 357 0.0000

LYS 357 CYS 358 -0.0003

CYS 358 THR 359 -0.0001

THR 359 TYR 360 -0.0002

TYR 360 VAL 361 0.0000

VAL 361 ARG 362 -0.0002

ARG 362 TYR 363 0.0002

TYR 363 ASN 364 -0.0075

ASN 364 ASP 365 -0.0000

ASP 365 VAL 366 0.0001

VAL 366 GLU 367 0.0000

GLU 367 ASN 368 -0.0002

ASN 368 ALA 369 -0.0003

ALA 369 ILE 370 -0.0001

ILE 370 LEU 371 -0.0004

LEU 371 ASP 372 0.0000

ASP 372 TYR 373 -0.0002

TYR 373 LEU 374 0.0001

LEU 374 SER 375 0.0047

SER 375 SER 376 0.0002

SER 376 LEU 377 -0.0003

LEU 377 ASN 378 0.0001

ASN 378 ASP 379 -0.0001

ASP 379 LEU 380 -0.0001

LEU 380 ASN 381 -0.0001

ASN 381 ASP 382 -0.0004

ASP 382 SER 383 0.0003

SER 383 THR 384 -0.0004

THR 384 LEU 385 0.0002

LEU 385 THR 386 -0.0148

THR 386 LYS 387 -0.0000

LYS 387 HIS 388 0.0002

HIS 388 ILE 389 0.0003

ILE 389 ASN 390 0.0000

ASN 390 SER 391 -0.0001

SER 391 MET 392 0.0001

MET 392 LEU 393 -0.0001

LEU 393 SER 394 -0.0002

SER 394 LYS 395 -0.0001

LYS 395 TYR 396 -0.0002

TYR 396 GLU 397 -0.0334

GLU 397 ASP 398 -0.0004

ASP 398 ASP 399 0.0003

ASP 399 ASN 400 0.0001

ASN 400 SER 401 -0.0001

SER 401 ASN 402 0.0001

ASN 402 MET 403 0.0005

MET 403 LYS 404 0.0000

LYS 404 THR 405 0.0003

THR 405 LYS 406 0.0001

LYS 406 LYS 407 -0.0002

LYS 407 GLN 408 -0.0166

GLN 408 MET 409 0.0004

MET 409 SER 410 0.0004

SER 410 GLU 411 0.0001

GLU 411 HIS 412 -0.0002

HIS 412 LEU 413 0.0001

LEU 413 SER 414 0.0000

SER 414 GLN 415 -0.0001

GLN 415 LYS 416 -0.0004

LYS 416 GLU 417 -0.0001

GLU 417 LYS 418 -0.0002

LYS 418 GLU 419 0.0096

GLU 419 LEU 420 -0.0001

LEU 420 LYS 421 0.0000

LYS 421 ASN 422 0.0003

ASN 422 LYS 423 0.0001

LYS 423 GLU 424 -0.0001

GLU 424 ASN 425 -0.0002

ASN 425 PHE 426 -0.0000

PHE 426 ILE 427 0.0002

ILE 427 PHE 428 0.0001

PHE 428 ASP 429 0.0002

ASP 429 LYS 430 -0.0040

LYS 430 TYR 431 -0.0000

TYR 431 GLU 432 0.0003

GLU 432 SER 433 0.0002

SER 433 GLY 434 0.0002

GLY 434 ILE 435 0.0001

ILE 435 TYR 436 0.0002

TYR 436 SER 437 -0.0001

SER 437 ASP 438 0.0003

ASP 438 GLU 439 0.0002

GLU 439 LEU 440 0.0000

LEU 440 PHE 441 0.0052

PHE 441 LEU 442 -0.0002

LEU 442 LYS 443 0.0001

LYS 443 ARG 444 0.0001

ARG 444 LYS 445 0.0000

LYS 445 ALA 446 -0.0003

ALA 446 ALA 447 0.0002

ALA 447 LEU 448 -0.0002

LEU 448 ASP 449 -0.0003

ASP 449 GLU 450 0.0002

GLU 450 GLU 451 -0.0000

GLU 451 PHE 452 -0.0165

PHE 452 LYS 453 0.0002

LYS 453 GLU 454 -0.0002

GLU 454 LEU 455 -0.0004

LEU 455 GLN 456 0.0002

GLN 456 ASN 457 -0.0001

ASN 457 ALA 458 -0.0002

ALA 458 LYS 459 -0.0005

LYS 459 ASN 460 0.0002

ASN 460 GLU 461 -0.0000

GLU 461 LEU 462 0.0003

LEU 462 ASN 463 -0.0122

ASN 463 GLY 464 0.0002

GLY 464 LEU 465 0.0001

LEU 465 GLN 466 -0.0000

GLN 466 ASP 467 -0.0001

ASP 467 THR 468 0.0002

THR 468 GLN 469 0.0005

GLN 469 SER 470 0.0001

SER 470 GLU 471 -0.0000

GLU 471 ILE 472 -0.0003

ILE 472 ASP 473 -0.0003

ASP 473 SER 474 -0.0324

SER 474 ASN 475 0.0001

ASN 475 THR 476 -0.0001

THR 476 VAL 477 0.0002

VAL 477 ARG 478 -0.0000

ARG 478 ASN 479 0.0002

ASN 479 ASN 480 0.0000

ASN 480 ILE 481 -0.0001

ILE 481 ASN 482 -0.0002

ASN 482 LYS 483 -0.0001

LYS 483 ILE 484 -0.0000

ILE 484 ILE 485 -0.0001

ILE 485 ASP 486 0.0004

ASP 486 GLN 487 0.0002

GLN 487 TYR 488 0.0001

TYR 488 HIS 489 -0.0001

HIS 489 ILE 490 -0.0002

ILE 490 GLU 491 0.0000

GLU 491 SER 492 0.0001

SER 492 SER 493 0.0000

SER 493 SER 494 -0.0001

SER 494 GLU 495 0.0002

GLU 495 LYS 496 0.0024

LYS 496 LYS 497 0.0002

LYS 497 ASN 498 0.0002

ASN 498 GLU 499 -0.0002

GLU 499 LEU 500 0.0001

LEU 500 LEU 501 0.0002

LEU 501 ARG 502 0.0000

ARG 502 MET 503 0.0001

MET 503 VAL 504 -0.0002

VAL 504 LEU 505 -0.0003

LEU 505 LYS 506 0.0004

LYS 506 ASP 507 -0.0158

ASP 507 VAL 508 0.0000

VAL 508 ILE 509 -0.0001

ILE 509 VAL 510 0.0004

VAL 510 ASN 511 -0.0001

ASN 511 MET 512 -0.0001

MET 512 THR 513 -0.0002

THR 513 GLN 514 0.0004

GLN 514 LYS 515 -0.0004

LYS 515 ARG 516 -0.0000

ARG 516 LYS 517 -0.0004

LYS 517 GLY 518 -0.0028

GLY 518 PRO 519 0.0004

PRO 519 ILE 520 -0.0001

ILE 520 PRO 521 0.0003

PRO 521 ALA 522 -0.0000

ALA 522 GLN 523 0.0004

GLN 523 PHE 524 -0.0003

PHE 524 GLU 525 0.0000

GLU 525 ILE 526 0.0001

ILE 526 THR 527 0.0000

THR 527 PRO 528 -0.0002

PRO 528 ILE 529 -0.0139

ILE 529 LEU 530 0.0002

LEU 530 ARG 531 0.0002

ARG 531 PHE 532 0.0002

PHE 532 ASN 533 -0.0001

ASN 533 PHE 534 -0.0001

PHE 534 ILE 535 0.0000

ILE 535 PHE 536 0.0002

PHE 536 ASP 537 0.0001

ASP 537 LEU 538 -0.0001

LEU 538 THR 539 0.0000

THR 539 ALA 540 0.0009

ALA 540 THR 541 -0.0001

THR 541 ASN 542 0.0002

ASN 542 SER 543 -0.0001

SER 543 PHE 544 -0.0001

PHE 544 HIS 545 -0.0002

HIS 545 MET 1 -0.0297

MET 1 GLU 2 0.0003

GLU 2 LEU 3 -0.0005

LEU 3 LYS 4 0.0002

LYS 4 ASN 5 -0.0001

ASN 5 ILE 6 0.0001

ILE 6 VAL 7 -0.0000

VAL 7 ASN 8 -0.0003

ASN 8 SER 9 0.0001

SER 9 TYR 10 -0.0002

TYR 10 ASN 11 -0.0001

ASN 11 ILE 12 -0.0601

ILE 12 THR 13 0.0001

THR 13 ASN 14 0.0001

ASN 14 ILE 15 0.0001

ILE 15 LEU 16 0.0000

LEU 16 GLY 17 -0.0000

GLY 17 TYR 18 0.0001

TYR 18 LEU 19 0.0001

LEU 19 ARG 20 -0.0002

ARG 20 ARG 21 0.0003

ARG 21 SER 22 0.0001

SER 22 ARG 23 0.0095

ARG 23 GLN 24 -0.0003

GLN 24 ASP 25 -0.0002

ASP 25 MET 26 -0.0000

MET 26 GLU 27 -0.0001

GLU 27 ARG 28 -0.0003

ARG 28 GLU 29 0.0000

GLU 29 LYS 30 0.0003

LYS 30 ARG 31 -0.0003

ARG 31 THR 32 0.0004

THR 32 GLY 33 0.0001

GLY 33 GLU 34 0.0362

GLU 34 ASP 35 -0.0000

ASP 35 THR 36 -0.0002

THR 36 LEU 37 0.0001

LEU 37 THR 38 -0.0001

THR 38 GLU 39 -0.0001

GLU 39 GLN 40 0.0001

GLN 40 LYS 41 -0.0004

LYS 41 GLU 42 0.0003

GLU 42 LEU 43 0.0001

LEU 43 MET 44 0.0002

MET 44 ASN 45 0.0061

ASN 45 LYS 46 -0.0005

LYS 46 ILE 47 -0.0002

ILE 47 LEU 48 -0.0002

LEU 48 THR 49 -0.0002

THR 49 ALA 50 -0.0001

ALA 50 ILE 51 -0.0002

ILE 51 GLU 52 -0.0004

GLU 52 ILE 53 0.0004

ILE 53 PRO 54 -0.0001

PRO 54 TYR 55 -0.0002

TYR 55 GLU 56 0.0500

GLU 56 LEU 57 0.0001

LEU 57 LYS 58 -0.0000

LYS 58 MET 59 -0.0002

MET 59 GLU 60 0.0001

GLU 60 ILE 61 0.0002

ILE 61 GLY 62 -0.0002

GLY 62 SER 63 0.0000

SER 63 GLY 64 0.0000

GLY 64 GLU 65 0.0003

GLU 65 SER 66 0.0000

SER 66 ILE 67 0.0273

ILE 67 ASP 68 -0.0004

ASP 68 GLY 69 0.0003

GLY 69 ARG 70 0.0004

ARG 70 PRO 71 0.0001

PRO 71 VAL 72 0.0003

VAL 72 PHE 73 0.0001

PHE 73 LYS 74 -0.0001

LYS 74 GLU 75 -0.0001

GLU 75 CYS 76 -0.0001

CYS 76 LEU 77 0.0003

LEU 77 LYS 78 -0.0018

LYS 78 ASP 79 -0.0002

ASP 79 LEU 80 0.0003

LEU 80 GLU 81 -0.0002

GLU 81 GLU 82 0.0001

GLU 82 GLY 83 -0.0004

GLY 83 LYS 84 0.0002

LYS 84 TYR 85 -0.0003

TYR 85 GLN 86 0.0001

GLN 86 ALA 87 -0.0005

ALA 87 ILE 88 0.0005

ILE 88 ALA 89 -0.0056

ALA 89 VAL 90 -0.0004

VAL 90 LYS 91 0.0003

LYS 91 GLU 92 0.0002

GLU 92 ILE 93 -0.0001

ILE 93 THR 94 0.0002

THR 94 ARG 95 0.0004

ARG 95 LEU 96 -0.0003

LEU 96 SER 97 0.0000

SER 97 ARG 98 -0.0001

ARG 98 GLY 99 -0.0000

GLY 99 SER 100 0.0187

SER 100 TYR 101 0.0001

TYR 101 SER 102 0.0003

SER 102 ASP 103 0.0001

ASP 103 ALA 104 -0.0002

ALA 104 GLY 105 -0.0001

GLY 105 GLN 106 0.0004

GLN 106 ILE 107 0.0001

ILE 107 VAL 108 0.0000

VAL 108 ASN 109 0.0000

ASN 109 LEU 110 0.0006

LEU 110 LEU 111 0.0049

LEU 111 GLN 112 -0.0001

GLN 112 SER 113 0.0001

SER 113 LYS 114 0.0002

LYS 114 ARG 115 -0.0001

ARG 115 LEU 116 -0.0001

LEU 116 ILE 117 0.0002

ILE 117 ILE 118 -0.0002

ILE 118 ILE 119 0.0000

ILE 119 THR 120 -0.0003

THR 120 PRO 121 -0.0001

PRO 121 TYR 122 0.0323

TYR 122 LYS 123 -0.0001

LYS 123 VAL 124 -0.0000

VAL 124 TYR 125 -0.0001

TYR 125 ASP 126 -0.0001

ASP 126 PRO 127 0.0000

PRO 127 ARG 128 -0.0002

ARG 128 ASN 129 -0.0000

ASN 129 PRO 130 0.0003

PRO 130 VAL 131 -0.0001

VAL 131 ASP 132 -0.0004

ASP 132 MET 133 -0.0205

MET 133 ARG 134 0.0001

ARG 134 GLN 135 0.0003

GLN 135 ILE 136 -0.0003

ILE 136 ARG 137 -0.0001

ARG 137 PHE 138 0.0000

PHE 138 GLU 139 0.0002

GLU 139 LEU 140 -0.0000

LEU 140 PHE 141 0.0002

PHE 141 MET 142 -0.0002

MET 142 ALA 143 0.0004

ALA 143 ARG 144 0.0236

ARG 144 GLU 145 0.0004

GLU 145 GLU 146 0.0002

GLU 146 PHE 147 0.0001

PHE 147 GLU 148 -0.0002

GLU 148 MET 149 0.0002

MET 149 THR 150 -0.0001

THR 150 ARG 151 0.0002

ARG 151 GLU 152 0.0002

GLU 152 ARG 153 0.0002

ARG 153 MET 154 -0.0003

MET 154 THR 155 0.0007

THR 155 GLY 156 -0.0001

GLY 156 ALA 157 -0.0002

ALA 157 LYS 158 -0.0001

LYS 158 TYR 159 -0.0001

TYR 159 THR 160 -0.0003

THR 160 TYR 161 -0.0001

TYR 161 ALA 162 0.0004

ALA 162 ALA 163 -0.0000

ALA 163 GLN 164 -0.0001

GLN 164 GLY 165 0.0003

GLY 165 LYS 166 -0.0359

LYS 166 TRP 167 0.0003

TRP 167 ILE 168 0.0001

ILE 168 SER 169 0.0003

SER 169 GLY 170 0.0001

GLY 170 LEU 171 0.0001

LEU 171 ALA 172 -0.0001

ALA 172 PRO 173 -0.0003

PRO 173 TYR 174 -0.0001

TYR 174 GLY 175 0.0006

GLY 175 TYR 176 -0.0004

TYR 176 GLN 177 -0.0306

GLN 177 LEU 178 0.0001

LEU 178 ASN 179 -0.0000

ASN 179 LYS 180 -0.0002

LYS 180 LYS 181 0.0001

LYS 181 THR 182 0.0003

THR 182 SER 183 -0.0002

SER 183 LYS 184 0.0001

LYS 184 LEU 185 -0.0005

LEU 185 ASP 186 0.0002

ASP 186 PRO 187 0.0001

PRO 187 VAL 188 -0.0124

VAL 188 GLU 189 0.0001

GLU 189 ASP 190 -0.0002

ASP 190 GLU 191 -0.0001

GLU 191 ALA 192 0.0002

ALA 192 LYS 193 0.0003

LYS 193 VAL 194 -0.0001

VAL 194 VAL 195 0.0001

VAL 195 GLN 196 -0.0001

GLN 196 LEU 197 -0.0004

LEU 197 ILE 198 -0.0002

ILE 198 PHE 199 -0.0034

PHE 199 ASN 200 0.0002

ASN 200 ILE 201 0.0001

ILE 201 PHE 202 -0.0003

PHE 202 LEU 203 -0.0001

LEU 203 ASN 204 -0.0002

ASN 204 GLY 205 -0.0003

GLY 205 LEU 206 -0.0000

LEU 206 ASN 207 -0.0004

ASN 207 GLY 208 0.0001

GLY 208 LYS 209 -0.0002

LYS 209 ASP 210 -0.0240

ASP 210 TYR 211 0.0000

TYR 211 SER 212 -0.0000

SER 212 TYR 213 0.0003

TYR 213 THR 214 -0.0003

THR 214 ALA 215 0.0000

ALA 215 ILE 216 -0.0002

ILE 216 ALA 217 -0.0000

ALA 217 SER 218 0.0002

SER 218 HIS 219 0.0003

HIS 219 LEU 220 0.0001

LEU 220 THR 221 0.0059

THR 221 ASN 222 -0.0001

ASN 222 LEU 223 -0.0002

LEU 223 GLN 224 0.0002

GLN 224 ILE 225 -0.0001

ILE 225 PRO 226 0.0001

PRO 226 THR 227 0.0001

THR 227 PRO 228 -0.0001

PRO 228 SER 229 0.0002

SER 229 GLY 230 0.0000

GLY 230 LYS 231 0.0004

LYS 231 LYS 232 -0.0499

LYS 232 ARG 233 0.0001

ARG 233 TRP 234 0.0002

TRP 234 ASN 235 -0.0002

ASN 235 GLN 236 0.0002

GLN 236 TYR 237 -0.0002

TYR 237 THR 238 0.0003

THR 238 ILE 239 -0.0002

ILE 239 LYS 240 -0.0001

LYS 240 ALA 241 -0.0002

ALA 241 ILE 242 0.0002

ILE 242 LEU 243 0.0205

LEU 243 GLN 244 0.0000

GLN 244 ASN 245 -0.0002

ASN 245 GLU 246 0.0001

GLU 246 VAL 247 -0.0000

VAL 247 TYR 248 0.0001

TYR 248 ILE 249 -0.0003

ILE 249 GLY 250 -0.0001

GLY 250 THR 251 0.0001

THR 251 VAL 252 -0.0002

VAL 252 LYS 253 0.0002

LYS 253 TYR 254 -0.1597

TYR 254 LYS 255 0.0000

LYS 255 VAL 256 0.0001

VAL 256 ARG 257 0.0000

ARG 257 GLU 258 0.0003

GLU 258 LYS 259 -0.0001

LYS 259 THR 260 -0.0002

THR 260 LYS 261 -0.0001

LYS 261 ASP 262 0.0002

ASP 262 GLY 263 -0.0002

GLY 263 LYS 264 0.0000

LYS 264 ARG 265 -0.0036

ARG 265 THR 266 -0.0000

THR 266 ILE 267 -0.0003

ILE 267 ARG 268 0.0001

ARG 268 PRO 269 -0.0005

PRO 269 GLU 270 0.0001

GLU 270 LYS 271 -0.0003

LYS 271 GLU 272 -0.0001

GLU 272 GLN 273 -0.0001

GLN 273 ILE 274 0.0003

ILE 274 VAL 275 0.0002

VAL 275 VAL 276 -0.1834

VAL 276 GLN 277 -0.0001

GLN 277 ASP 278 0.0000

ASP 278 ALA 279 0.0002

ALA 279 HIS 280 0.0003

HIS 280 ALA 281 0.0001

ALA 281 PRO 282 0.0000

PRO 282 ILE 283 0.0001

ILE 283 ILE 284 0.0000

ILE 284 ASP 285 -0.0003

ASP 285 LYS 286 0.0001

LYS 286 GLU 287 0.0149

GLU 287 GLN 288 -0.0001

GLN 288 PHE 289 0.0002

PHE 289 GLN 290 -0.0000

GLN 290 GLN 291 -0.0002

GLN 291 SER 292 -0.0001

SER 292 GLN 293 0.0001

GLN 293 VAL 294 0.0002

VAL 294 LYS 295 0.0001

LYS 295 ILE 296 -0.0001

ILE 296 ALA 297 0.0001

ALA 297 ASN 298 0.1500

ASN 298 LYS 299 -0.0003

LYS 299 VAL 300 0.0004

VAL 300 PRO 301 -0.0002

PRO 301 LEU 302 0.0004

LEU 302 LEU 303 0.0001

LEU 303 PRO 304 0.0001

PRO 304 ASN 305 -0.0002

ASN 305 LYS 306 -0.0001

LYS 306 ASP 307 -0.0001

ASP 307 GLU 308 0.0000

GLU 308 PHE 309 0.2057

PHE 309 GLU 310 0.0000

GLU 310 LEU 311 0.0003

LEU 311 SER 312 0.0000

SER 312 GLU 313 0.0000

GLU 313 LEU 314 0.0001

LEU 314 ALA 315 -0.0003

ALA 315 GLY 316 0.0002

GLY 316 VAL 317 -0.0002

VAL 317 CYS 318 0.0001

CYS 318 THR 319 -0.0001

THR 319 CYS 320 -0.0655

CYS 320 SER 321 -0.0001

SER 321 LYS 322 -0.0004

LYS 322 CYS 323 -0.0002

CYS 323 GLY 324 0.0002

GLY 324 GLU 325 -0.0002

GLU 325 PRO 326 0.0002

PRO 326 LEU 327 0.0002

LEU 327 SER 328 -0.0005

SER 328 LYS 329 -0.0000

LYS 329 TYR 330 -0.0001

TYR 330 GLU 331 -0.0247

GLU 331 SER 332 -0.0001

SER 332 LYS 333 0.0001

LYS 333 ARG 334 -0.0001

ARG 334 ILE 335 0.0002

ILE 335 ARG 336 0.0002

ARG 336 LYS 337 0.0001

LYS 337 ASN 338 0.0003

ASN 338 LYS 339 -0.0003

LYS 339 ASP 340 -0.0002

ASP 340 GLY 341 -0.0002

GLY 341 THR 342 0.0706

THR 342 GLU 343 -0.0002

GLU 343 SER 344 0.0000

SER 344 VAL 345 0.0001

VAL 345 TYR 346 0.0001

TYR 346 HIS 347 -0.0001

HIS 347 VAL 348 -0.0001

VAL 348 LYS 349 -0.0000

LYS 349 SER 350 0.0003

SER 350 LEU 351 0.0001

LEU 351 THR 352 -0.0001

THR 352 CYS 353 -0.1268

CYS 353 LYS 354 0.0001

LYS 354 LYS 355 -0.0000

LYS 355 ASN 356 -0.0003

ASN 356 LYS 357 -0.0000

LYS 357 CYS 358 0.0000

CYS 358 THR 359 -0.0003

THR 359 TYR 360 -0.0003

TYR 360 VAL 361 0.0004

VAL 361 ARG 362 0.0000

ARG 362 TYR 363 -0.0003

TYR 363 ASN 364 0.0273

ASN 364 ASP 365 0.0002

ASP 365 VAL 366 0.0001

VAL 366 GLU 367 -0.0000

GLU 367 ASN 368 0.0001

ASN 368 ALA 369 -0.0002

ALA 369 ILE 370 0.0000

ILE 370 LEU 371 0.0000

LEU 371 ASP 372 0.0001

ASP 372 TYR 373 0.0001

TYR 373 LEU 374 0.0003

LEU 374 SER 375 -0.0441

SER 375 SER 376 -0.0000

SER 376 LEU 377 0.0002

LEU 377 ASN 378 0.0003

ASN 378 ASP 379 0.0001

ASP 379 LEU 380 -0.0002

LEU 380 ASN 381 -0.0001

ASN 381 ASP 382 -0.0000

ASP 382 SER 383 0.0001

SER 383 THR 384 -0.0001

THR 384 LEU 385 -0.0001

LEU 385 THR 386 0.0173

THR 386 LYS 387 -0.0001

LYS 387 HIS 388 -0.0004

HIS 388 ILE 389 0.0002

ILE 389 ASN 390 -0.0000

ASN 390 SER 391 0.0000

SER 391 MET 392 0.0001

MET 392 LEU 393 -0.0004

LEU 393 SER 394 0.0000

SER 394 LYS 395 -0.0004

LYS 395 TYR 396 -0.0000

TYR 396 GLU 397 -0.1765

GLU 397 ASP 398 0.0002

ASP 398 ASP 399 -0.0001

ASP 399 ASN 400 0.0001

ASN 400 SER 401 0.0000

SER 401 ASN 402 -0.0003

ASN 402 MET 403 -0.0003

MET 403 LYS 404 -0.0001

LYS 404 THR 405 -0.0002

THR 405 LYS 406 0.0000

LYS 406 LYS 407 -0.0002

LYS 407 GLN 408 -0.0113

GLN 408 MET 409 0.0001

MET 409 SER 410 0.0000

SER 410 GLU 411 0.0004

GLU 411 HIS 412 0.0003

HIS 412 LEU 413 0.0002

LEU 413 SER 414 0.0001

SER 414 GLN 415 0.0002

GLN 415 LYS 416 -0.0001

LYS 416 GLU 417 0.0003

GLU 417 LYS 418 0.0004

LYS 418 GLU 419 0.0122

GLU 419 LEU 420 -0.0002

LEU 420 LYS 421 0.0002

LYS 421 ASN 422 -0.0002

ASN 422 LYS 423 -0.0001

LYS 423 GLU 424 0.0002

GLU 424 ASN 425 0.0000

ASN 425 PHE 426 -0.0001

PHE 426 ILE 427 -0.0000

ILE 427 PHE 428 -0.0004

PHE 428 ASP 429 0.0002

ASP 429 LYS 430 -0.0122

LYS 430 TYR 431 -0.0003

TYR 431 GLU 432 0.0003

GLU 432 SER 433 0.0003

SER 433 GLY 434 -0.0001

GLY 434 ILE 435 -0.0000

ILE 435 TYR 436 -0.0003

TYR 436 SER 437 -0.0000

SER 437 ASP 438 -0.0000

ASP 438 GLU 439 -0.0001

GLU 439 LEU 440 0.0003

LEU 440 PHE 441 -0.0202

PHE 441 LEU 442 -0.0001

LEU 442 LYS 443 0.0001

LYS 443 ARG 444 -0.0001

ARG 444 LYS 445 0.0000

LYS 445 ALA 446 -0.0004

ALA 446 ALA 447 -0.0003

ALA 447 LEU 448 -0.0000

LEU 448 ASP 449 -0.0005

ASP 449 GLU 450 0.0003

GLU 450 GLU 451 0.0003

GLU 451 PHE 452 -0.0220

PHE 452 LYS 453 0.0000

LYS 453 GLU 454 0.0000

GLU 454 LEU 455 0.0001

LEU 455 GLN 456 0.0001

GLN 456 ASN 457 0.0001

ASN 457 ALA 458 -0.0003

ALA 458 LYS 459 -0.0001

LYS 459 ASN 460 -0.0002

ASN 460 GLU 461 -0.0001

GLU 461 LEU 462 0.0003

LEU 462 ASN 463 -0.0330

ASN 463 GLY 464 -0.0001

GLY 464 LEU 465 -0.0001

LEU 465 GLN 466 0.0004

GLN 466 ASP 467 0.0001

ASP 467 THR 468 -0.0002

THR 468 GLN 469 0.0000

GLN 469 SER 470 -0.0003

SER 470 GLU 471 0.0003

GLU 471 ILE 472 -0.0001

ILE 472 ASP 473 -0.0004

ASP 473 SER 474 0.1415

SER 474 ASN 475 -0.0001

ASN 475 THR 476 0.0002

THR 476 VAL 477 0.0001

VAL 477 ARG 478 0.0001

ARG 478 ASN 479 -0.0002

ASN 479 ASN 480 -0.0002

ASN 480 ILE 481 0.0002

ILE 481 ASN 482 0.0001

ASN 482 LYS 483 0.0001

LYS 483 ILE 484 -0.0002

ILE 484 ILE 485 0.0452

ILE 485 ASP 486 0.0001

ASP 486 GLN 487 0.0002

GLN 487 TYR 488 -0.0001

TYR 488 HIS 489 0.0002

HIS 489 ILE 490 0.0001

ILE 490 GLU 491 -0.0001

GLU 491 SER 492 0.0000

SER 492 SER 493 -0.0001

SER 493 SER 494 0.0003

SER 494 GLU 495 0.0001

GLU 495 LYS 496 -0.0072

LYS 496 LYS 497 -0.0004

LYS 497 ASN 498 0.0001

ASN 498 GLU 499 -0.0004

GLU 499 LEU 500 0.0003

LEU 500 LEU 501 0.0003

LEU 501 ARG 502 -0.0001

ARG 502 MET 503 -0.0001

MET 503 VAL 504 0.0000

VAL 504 LEU 505 0.0003

LEU 505 LYS 506 -0.0004

LYS 506 ASP 507 -0.1417

ASP 507 VAL 508 0.0004

VAL 508 ILE 509 -0.0003

ILE 509 VAL 510 -0.0001

VAL 510 ASN 511 0.0003

ASN 511 MET 512 -0.0002

MET 512 THR 513 -0.0000

THR 513 GLN 514 0.0002

GLN 514 LYS 515 0.0000

LYS 515 ARG 516 -0.0004

ARG 516 LYS 517 -0.0001

LYS 517 GLY 518 0.0078

GLY 518 PRO 519 -0.0002

PRO 519 ILE 520 0.0001

ILE 520 PRO 521 0.0004

PRO 521 ALA 522 -0.0003

ALA 522 GLN 523 -0.0000

GLN 523 PHE 524 0.0001

PHE 524 GLU 525 -0.0002

GLU 525 ILE 526 0.0001

ILE 526 THR 527 0.0002

THR 527 PRO 528 0.0001

PRO 528 ILE 529 -0.0525

ILE 529 LEU 530 0.0001

LEU 530 ARG 531 -0.0001

ARG 531 PHE 532 -0.0004

PHE 532 ASN 533 0.0001

ASN 533 PHE 534 0.0001

PHE 534 ILE 535 -0.0001

ILE 535 PHE 536 -0.0002

PHE 536 ASP 537 -0.0000

ASP 537 LEU 538 -0.0000

LEU 538 THR 539 -0.0000

THR 539 ALA 540 0.0194

ALA 540 THR 541 -0.0000

THR 541 ASN 542 -0.0000

ASN 542 SER 543 0.0001

SER 543 PHE 544 -0.0000

PHE 544 HIS 545 -0.0000

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: April 25th, 2023.

Should you encounter any unexpected behaviour, please let us know.

*** ***

CA strain for 2406101858502122271

--- normal mode 27 ---

Should you encounter any unexpected behaviour,
please let us know.

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