Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE 06-MAY-21 7OG5 *

CA strain for 22121317415457420

--- normal mode 11 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
SER 1 ARG 2 0.0003

ARG 2 ARG 3 -0.0001

ARG 3 PHE 4 0.0001

PHE 4 VAL 5 0.0000

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 -0.0002

THR 8 SER 9 0.0003

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 -0.0073

PHE 11 THR 12 0.0001

THR 12 ASN 13 0.0001

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 0.0004

VAL 16 TYR 17 0.0001

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 -0.0001

ARG 19 PHE 20 0.0001

PHE 20 ASP 21 -0.0099

ASP 21 GLU 22 0.0002

GLU 22 GLU 23 0.0002

GLU 23 PRO 24 -0.0003

PRO 24 MET 25 0.0005

MET 25 GLN 26 -0.0004

GLN 26 ALA 27 0.0000

ALA 27 ILE 28 0.0002

ILE 28 SER 29 -0.0000

SER 29 VAL 30 0.0002

VAL 30 PHE 31 -0.0040

PHE 31 LEU 32 0.0003

LEU 32 GLY 33 0.0001

GLY 33 LEU 34 -0.0000

LEU 34 ALA 35 0.0001

ALA 35 ARG 36 0.0003

ARG 36 ARG 37 -0.0003

ARG 37 ALA 38 -0.0004

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 0.0002

ALA 40 GLU 41 0.0381

GLU 41 PHE 42 0.0002

PHE 42 TYR 43 0.0001

TYR 43 MET 44 -0.0003

MET 44 PRO 45 0.0000

PRO 45 GLY 46 -0.0002

GLY 46 PRO 47 0.0002

PRO 47 VAL 48 0.0002

VAL 48 TYR 49 0.0003

TYR 49 GLN 50 -0.0001

GLN 50 GLU 51 -0.0354

GLU 51 LEU 52 0.0000

LEU 52 CYS 53 0.0004

CYS 53 ASN 54 0.0001

ASN 54 LEU 55 -0.0003

LEU 55 ARG 56 -0.0000

ARG 56 SER 57 -0.0001

SER 57 MET 58 -0.0001

MET 58 ASP 59 0.0004

ASP 59 LEU 60 -0.0002

LEU 60 ILE 61 -0.0225

ILE 61 GLY 62 -0.0003

GLY 62 ALA 63 -0.0004

ALA 63 GLU 64 0.0001

GLU 64 PHE 65 0.0001

PHE 65 GLU 66 -0.0001

GLU 66 THR 67 0.0003

THR 67 GLU 68 -0.0003

GLU 68 VAL 69 0.0003

VAL 69 TYR 70 0.0001

TYR 70 ILE 71 0.0006

ILE 71 ARG 72 -0.0003

ARG 72 SER 73 0.0004

SER 73 PRO 74 0.0003

PRO 74 ARG 75 0.0000

ARG 75 ARG 76 0.0004

ARG 76 PHE 77 0.0002

PHE 77 SER 78 -0.0001

SER 78 MET 79 0.0002

MET 79 THR 80 0.0003

THR 80 ILE 81 0.0806

ILE 81 PRO 82 -0.0001

PRO 82 SER 83 0.0000

SER 83 GLU 84 0.0001

GLU 84 VAL 85 0.0003

VAL 85 LEU 86 -0.0000

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 0.0003

GLU 88 PHE 89 0.0001

PHE 89 ILE 90 -0.0003

ILE 90 GLU 91 -0.0047

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 0.0000

ARG 94 THR 95 0.0002

THR 95 ARG 96 0.0002

ARG 96 ILE 97 -0.0002

ILE 97 GLN 98 0.0000

GLN 98 GLU 131 -0.0039

GLU 131 ALA 132 0.0003

ALA 132 MET 133 -0.0003

MET 133 ARG 134 -0.0001

ARG 134 ARG 135 0.0004

ARG 135 GLY 136 0.0003

GLY 136 ILE 137 0.0001

ILE 137 LEU 138 -0.0002

LEU 138 ASP 139 0.0002

ASP 139 SER 140 -0.0002

SER 140 ARG 141 0.0141

ARG 141 GLU 142 -0.0001

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 0.0001

ILE 144 ASP 145 0.0005

ASP 145 VAL 146 -0.0000

VAL 146 VAL 147 -0.0001

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0000

LEU 149 ALA 150 -0.0001

ALA 150 TYR 151 -0.0008

TYR 151 GLU 152 0.0004

GLU 152 LEU 153 -0.0000

LEU 153 ASP 154 -0.0002

ASP 154 ALA 155 -0.0003

ALA 155 THR 156 0.0002

THR 156 LEU 157 -0.0003

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 0.0003

SER 159 ALA 160 -0.0002

ALA 160 ASP 161 0.0022

ASP 161 GLU 162 0.0000

GLU 162 GLY 163 -0.0001

GLY 163 MET 164 -0.0001

MET 164 ARG 165 0.0001

ARG 165 LYS 166 0.0001

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 0.0001

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 0.0001

ARG 170 ILE 171 0.0244

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 0.0001

LYS 174 LEU 175 0.0004

LEU 175 VAL 176 -0.0003

VAL 176 ASN 177 0.0002

ASN 177 PRO 178 0.0001

PRO 178 ARG 179 0.0003

ARG 179 TYR 180 0.0002

TYR 180 LEU 181 0.0223

LEU 181 ARG 182 -0.0000

ARG 182 GLY 183 0.0002

GLY 183 VAL 184 -0.0002

VAL 184 MET 185 0.0003

MET 185 GLN 186 0.0001

GLN 186 ASN 187 -0.0002

ASN 187 LEU 188 0.0001

LEU 188 ALA 189 0.0003

ALA 189 SER 1 -0.0444

SER 1 ARG 2 -0.0000

ARG 2 ARG 3 -0.0005

ARG 3 PHE 4 0.0004

PHE 4 VAL 5 -0.0006

VAL 5 LEU 6 0.0004

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 0.0001

THR 8 SER 9 0.0005

SER 9 VAL 10 0.0002

VAL 10 PHE 11 0.0051

PHE 11 THR 12 -0.0001

THR 12 ASN 13 -0.0003

ASN 13 PRO 14 -0.0001

PRO 14 ASP 15 0.0000

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 0.0002

TYR 17 LEU 18 0.0002

LEU 18 ARG 19 -0.0001

ARG 19 PHE 20 0.0001

PHE 20 ASP 21 0.0229

ASP 21 GLU 22 -0.0000

GLU 22 GLU 23 0.0001

GLU 23 PRO 24 0.0003

PRO 24 MET 25 -0.0001

MET 25 GLN 26 -0.0001

GLN 26 ALA 27 -0.0005

ALA 27 ILE 28 0.0002

ILE 28 SER 29 -0.0000

SER 29 VAL 30 0.0003

VAL 30 PHE 31 0.0013

PHE 31 LEU 32 -0.0000

LEU 32 GLY 33 -0.0002

GLY 33 LEU 34 -0.0001

LEU 34 ALA 35 -0.0001

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 -0.0003

ARG 37 ALA 38 -0.0002

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 -0.0002

ALA 40 GLU 41 -0.0457

GLU 41 PHE 42 -0.0003

PHE 42 TYR 43 0.0001

TYR 43 MET 44 0.0001

MET 44 PRO 45 -0.0002

PRO 45 GLY 46 -0.0003

GLY 46 PRO 47 -0.0001

PRO 47 VAL 48 -0.0001

VAL 48 TYR 49 -0.0000

TYR 49 GLN 50 0.0000

GLN 50 GLU 51 0.0192

GLU 51 LEU 52 0.0002

LEU 52 CYS 53 -0.0000

CYS 53 ASN 54 0.0002

ASN 54 LEU 55 0.0001

LEU 55 ARG 56 0.0000

ARG 56 SER 57 -0.0000

SER 57 MET 58 0.0000

MET 58 ASP 59 -0.0001

ASP 59 LEU 60 0.0002

LEU 60 ILE 61 -0.0205

ILE 61 GLY 62 0.0000

GLY 62 ALA 63 0.0006

ALA 63 GLU 64 0.0001

GLU 64 PHE 65 0.0002

PHE 65 GLU 66 0.0001

GLU 66 THR 67 0.0003

THR 67 GLU 68 -0.0000

GLU 68 VAL 69 -0.0002

VAL 69 TYR 70 0.0002

TYR 70 ILE 71 0.0104

ILE 71 ARG 72 -0.0000

ARG 72 SER 73 0.0003

SER 73 PRO 74 -0.0004

PRO 74 ARG 75 -0.0003

ARG 75 ARG 76 -0.0003

ARG 76 PHE 77 0.0000

PHE 77 SER 78 -0.0003

SER 78 MET 79 0.0001

MET 79 THR 80 -0.0003

THR 80 ILE 81 -0.0367

ILE 81 PRO 82 0.0000

PRO 82 SER 83 -0.0002

SER 83 GLU 84 0.0002

GLU 84 VAL 85 -0.0002

VAL 85 LEU 86 -0.0002

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 0.0001

GLU 88 PHE 89 0.0002

PHE 89 ILE 90 -0.0003

ILE 90 GLU 91 -0.0080

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 -0.0002

ARG 94 THR 95 -0.0001

THR 95 ARG 96 0.0004

ARG 96 ILE 97 0.0001

ILE 97 GLN 98 0.0002

GLN 98 ARG 99 0.0004

ARG 99 GLY 100 0.0002

GLY 100 LEU 101 0.0039

LEU 101 ARG 102 0.0004

ARG 102 LEU 125 0.0015

LEU 125 ARG 126 -0.0000

ARG 126 GLU 127 0.0003

GLU 127 ARG 128 -0.0002

ARG 128 TYR 129 -0.0001

TYR 129 ARG 130 0.0003

ARG 130 GLU 131 -0.0000

GLU 131 ALA 132 -0.0001

ALA 132 MET 133 0.0001

MET 133 ARG 134 -0.0001

ARG 134 ARG 135 0.0161

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 0.0003

ILE 137 LEU 138 -0.0003

LEU 138 ASP 139 -0.0004

ASP 139 SER 140 -0.0001

SER 140 ARG 141 0.0003

ARG 141 GLU 142 -0.0001

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 -0.0003

ILE 144 ASP 145 0.0111

ASP 145 VAL 146 -0.0002

VAL 146 VAL 147 -0.0002

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0003

LEU 149 ALA 150 -0.0004

ALA 150 TYR 151 0.0002

TYR 151 GLU 152 -0.0001

GLU 152 LEU 153 0.0001

LEU 153 ASP 154 0.0000

ASP 154 ALA 155 -0.0107

ALA 155 THR 156 0.0002

THR 156 LEU 157 0.0001

LEU 157 VAL 158 0.0001

VAL 158 SER 159 0.0001

SER 159 ALA 160 -0.0001

ALA 160 ASP 161 -0.0002

ASP 161 GLU 162 0.0000

GLU 162 GLY 163 -0.0002

GLY 163 MET 164 -0.0003

MET 164 ARG 165 0.0213

ARG 165 LYS 166 0.0002

LYS 166 PHE 167 -0.0001

PHE 167 ALA 168 0.0003

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 -0.0000

ARG 170 ILE 171 0.0000

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0004

ILE 173 LYS 174 -0.0000

LYS 174 LEU 175 -0.0151

LEU 175 VAL 176 -0.0002

VAL 176 ASN 177 -0.0001

ASN 177 PRO 178 0.0002

PRO 178 ARG 179 -0.0001

ARG 179 TYR 180 -0.0003

TYR 180 LEU 181 0.0000

LEU 181 ARG 182 -0.0001

ARG 182 GLY 183 -0.0000

GLY 183 VAL 184 0.0000

VAL 184 MET 185 -0.0148

MET 185 GLN 186 -0.0003

GLN 186 ASN 187 0.0002

ASN 187 LEU 188 -0.0001

LEU 188 ALA 189 -0.0003

ALA 189 SER 1 -0.0239

SER 1 ARG 2 -0.0001

ARG 2 ARG 3 0.0001

ARG 3 PHE 4 -0.0000

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 -0.0004

LEU 6 ASP 7 0.0001

ASP 7 THR 8 0.0003

THR 8 SER 9 -0.0001

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0265

PHE 11 THR 12 -0.0002

THR 12 ASN 13 -0.0002

ASN 13 PRO 14 -0.0001

PRO 14 ASP 15 -0.0000

ASP 15 VAL 16 -0.0002

VAL 16 TYR 17 -0.0003

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 0.0000

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 -0.0011

ASP 21 GLU 22 -0.0001

GLU 22 GLU 23 -0.0001

GLU 23 PRO 24 -0.0001

PRO 24 MET 25 -0.0000

MET 25 GLN 26 0.0003

GLN 26 ALA 27 0.0003

ALA 27 ILE 28 0.0002

ILE 28 SER 29 -0.0001

SER 29 VAL 30 -0.0004

VAL 30 PHE 31 -0.0032

PHE 31 LEU 32 -0.0001

LEU 32 GLY 33 0.0000

GLY 33 LEU 34 -0.0001

LEU 34 ALA 35 0.0001

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 -0.0002

ARG 37 ALA 38 -0.0000

ALA 38 ASP 39 0.0005

ASP 39 ALA 40 -0.0001

ALA 40 GLU 41 0.0059

GLU 41 PHE 42 -0.0001

PHE 42 TYR 43 0.0002

TYR 43 MET 44 -0.0001

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0003

GLY 46 PRO 47 -0.0001

PRO 47 VAL 48 0.0004

VAL 48 TYR 49 0.0001

TYR 49 GLN 50 0.0001

GLN 50 GLU 51 -0.0357

GLU 51 LEU 52 0.0003

LEU 52 CYS 53 0.0001

CYS 53 ASN 54 -0.0003

ASN 54 LEU 55 -0.0001

LEU 55 ARG 56 0.0001

ARG 56 SER 57 -0.0001

SER 57 MET 58 -0.0000

MET 58 ASP 59 -0.0003

ASP 59 LEU 60 0.0002

LEU 60 ILE 61 -0.0003

ILE 61 GLY 62 0.0002

GLY 62 ALA 63 0.0003

ALA 63 GLU 64 0.0004

GLU 64 PHE 65 -0.0001

PHE 65 GLU 66 0.0001

GLU 66 THR 67 0.0002

THR 67 GLU 68 0.0002

GLU 68 VAL 69 -0.0001

VAL 69 TYR 70 -0.0000

TYR 70 ILE 71 -0.0037

ILE 71 ARG 72 -0.0002

ARG 72 SER 73 -0.0001

SER 73 PRO 74 0.0002

PRO 74 ARG 75 0.0001

ARG 75 ARG 76 0.0001

ARG 76 PHE 77 0.0001

PHE 77 SER 78 -0.0003

SER 78 MET 79 -0.0001

MET 79 THR 80 0.0003

THR 80 ILE 81 -0.0283

ILE 81 PRO 82 -0.0002

PRO 82 SER 83 0.0003

SER 83 GLU 84 -0.0004

GLU 84 VAL 85 -0.0001

VAL 85 LEU 86 -0.0000

LEU 86 TYR 87 0.0003

TYR 87 GLU 88 0.0001

GLU 88 PHE 89 0.0001

PHE 89 ILE 90 -0.0000

ILE 90 GLU 91 -0.0003

GLU 91 GLU 92 0.0004

GLU 92 VAL 93 0.0002

VAL 93 ARG 94 -0.0004

ARG 94 THR 95 -0.0002

THR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0002

ILE 97 GLN 98 0.0003

GLN 98 GLU 131 -0.0013

GLU 131 ALA 132 0.0001

ALA 132 MET 133 -0.0003

MET 133 ARG 134 0.0001

ARG 134 ARG 135 -0.0003

ARG 135 GLY 136 0.0002

GLY 136 ILE 137 0.0002

ILE 137 LEU 138 0.0000

LEU 138 ASP 139 -0.0000

ASP 139 SER 140 0.0003

SER 140 ARG 141 0.0173

ARG 141 GLU 142 -0.0003

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 -0.0002

ILE 144 ASP 145 -0.0000

ASP 145 VAL 146 -0.0001

VAL 146 VAL 147 0.0001

VAL 147 LEU 148 0.0000

LEU 148 LEU 149 0.0001

LEU 149 ALA 150 -0.0000

ALA 150 TYR 151 0.0223

TYR 151 GLU 152 -0.0003

GLU 152 LEU 153 -0.0000

LEU 153 ASP 154 -0.0002

ASP 154 ALA 155 0.0001

ALA 155 THR 156 -0.0004

THR 156 LEU 157 0.0002

LEU 157 VAL 158 0.0001

VAL 158 SER 159 -0.0003

SER 159 ALA 160 -0.0000

ALA 160 ASP 161 -0.0025

ASP 161 GLU 162 -0.0001

GLU 162 GLY 163 -0.0001

GLY 163 MET 164 -0.0000

MET 164 ARG 165 0.0000

ARG 165 LYS 166 0.0004

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 -0.0003

ALA 168 GLU 169 0.0003

GLU 169 ARG 170 0.0001

ARG 170 ILE 171 0.0047

ILE 171 GLY 172 -0.0002

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 0.0003

LYS 174 LEU 175 -0.0001

LEU 175 VAL 176 -0.0000

VAL 176 ASN 177 -0.0000

ASN 177 PRO 178 0.0001

PRO 178 ARG 179 0.0001

ARG 179 TYR 180 0.0000

TYR 180 LEU 181 -0.0137

LEU 181 ARG 182 0.0003

ARG 182 GLY 183 0.0000

GLY 183 VAL 184 -0.0001

VAL 184 MET 185 -0.0004

MET 185 GLN 186 0.0003

GLN 186 ASN 187 0.0000

ASN 187 LEU 188 0.0000

LEU 188 ALA 189 0.0002

ALA 189 SER 1 -0.0839

SER 1 ARG 2 0.0002

ARG 2 ARG 3 -0.0003

ARG 3 PHE 4 -0.0002

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0001

SER 9 VAL 10 0.0001

VAL 10 PHE 11 -0.0004

PHE 11 THR 12 -0.0000

THR 12 ASN 13 0.0002

ASN 13 PRO 14 -0.0003

PRO 14 ASP 15 -0.0000

ASP 15 VAL 16 0.0003

VAL 16 TYR 17 0.0000

TYR 17 LEU 18 0.0001

LEU 18 ARG 19 0.0000

ARG 19 PHE 20 -0.0004

PHE 20 ASP 21 0.0126

ASP 21 GLU 22 0.0001

GLU 22 GLU 23 0.0004

GLU 23 PRO 24 -0.0001

PRO 24 MET 25 -0.0001

MET 25 GLN 26 -0.0004

GLN 26 ALA 27 -0.0000

ALA 27 ILE 28 -0.0000

ILE 28 SER 29 0.0003

SER 29 VAL 30 -0.0002

VAL 30 PHE 31 -0.0038

PHE 31 LEU 32 -0.0002

LEU 32 GLY 33 0.0002

GLY 33 LEU 34 -0.0000

LEU 34 ALA 35 0.0003

ALA 35 ARG 36 0.0000

ARG 36 ARG 37 0.0000

ARG 37 ALA 38 0.0003

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 0.0002

ALA 40 GLU 41 -0.0101

GLU 41 PHE 42 -0.0001

PHE 42 TYR 43 0.0004

TYR 43 MET 44 0.0001

MET 44 PRO 45 0.0002

PRO 45 GLY 46 0.0000

GLY 46 PRO 47 0.0000

PRO 47 VAL 48 0.0002

VAL 48 TYR 49 -0.0002

TYR 49 GLN 50 0.0000

GLN 50 GLU 51 -0.0033

GLU 51 LEU 52 0.0001

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 -0.0001

ASN 54 LEU 55 -0.0002

LEU 55 ARG 56 -0.0000

ARG 56 SER 57 0.0001

SER 57 MET 58 -0.0004

MET 58 ASP 59 0.0004

ASP 59 LEU 60 -0.0001

LEU 60 ILE 61 -0.0083

ILE 61 GLY 62 0.0001

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 -0.0001

GLU 64 PHE 65 -0.0000

PHE 65 GLU 66 -0.0003

GLU 66 THR 67 -0.0001

THR 67 GLU 68 0.0000

GLU 68 VAL 69 0.0001

VAL 69 TYR 70 0.0001

TYR 70 ILE 71 -0.0205

ILE 71 ARG 72 0.0001

ARG 72 SER 73 0.0001

SER 73 PRO 74 0.0002

PRO 74 ARG 75 -0.0000

ARG 75 ARG 76 0.0001

ARG 76 PHE 77 -0.0001

PHE 77 SER 78 -0.0000

SER 78 MET 79 0.0002

MET 79 THR 80 -0.0003

THR 80 ILE 81 0.0324

ILE 81 PRO 82 0.0001

PRO 82 SER 83 -0.0001

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 0.0001

VAL 85 LEU 86 -0.0002

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 -0.0003

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 -0.0179

GLU 91 GLU 92 0.0000

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 -0.0000

ARG 94 THR 95 -0.0003

THR 95 ARG 96 -0.0002

ARG 96 ILE 97 0.0003

ILE 97 GLN 98 0.0001

GLN 98 GLU 131 -0.0008

GLU 131 ALA 132 0.0001

ALA 132 MET 133 -0.0000

MET 133 ARG 134 0.0001

ARG 134 ARG 135 0.0001

ARG 135 GLY 136 -0.0001

GLY 136 ILE 137 0.0001

ILE 137 LEU 138 -0.0000

LEU 138 ASP 139 -0.0004

ASP 139 SER 140 0.0001

SER 140 ARG 141 0.0118

ARG 141 GLU 142 -0.0002

GLU 142 ASP 143 0.0000

ASP 143 ILE 144 -0.0001

ILE 144 ASP 145 -0.0001

ASP 145 VAL 146 -0.0001

VAL 146 VAL 147 0.0002

VAL 147 LEU 148 -0.0004

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0003

ALA 150 TYR 151 -0.0093

TYR 151 GLU 152 -0.0000

GLU 152 LEU 153 0.0002

LEU 153 ASP 154 0.0001

ASP 154 ALA 155 -0.0004

ALA 155 THR 156 0.0000

THR 156 LEU 157 0.0003

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 0.0002

SER 159 ALA 160 0.0001

ALA 160 ASP 161 -0.0076

ASP 161 GLU 162 -0.0001

GLU 162 GLY 163 -0.0002

GLY 163 MET 164 -0.0001

MET 164 ARG 165 0.0001

ARG 165 LYS 166 0.0001

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 -0.0001

ALA 168 GLU 169 0.0001

GLU 169 ARG 170 -0.0004

ARG 170 ILE 171 0.0116

ILE 171 GLY 172 -0.0003

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 0.0000

LYS 174 LEU 175 0.0002

LEU 175 VAL 176 0.0001

VAL 176 ASN 177 -0.0000

ASN 177 PRO 178 -0.0002

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 -0.0001

TYR 180 LEU 181 0.0243

LEU 181 ARG 182 -0.0002

ARG 182 GLY 183 0.0001

GLY 183 VAL 184 0.0002

VAL 184 MET 185 -0.0002

MET 185 GLN 186 -0.0005

GLN 186 ASN 187 -0.0000

ASN 187 LEU 188 -0.0000

LEU 188 ALA 189 -0.0003

ALA 189 SER 1 -0.0303

SER 1 ARG 2 0.0001

ARG 2 ARG 3 0.0001

ARG 3 PHE 4 -0.0001

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 0.0004

THR 8 SER 9 -0.0001

SER 9 VAL 10 -0.0000

VAL 10 PHE 11 0.0179

PHE 11 THR 12 -0.0002

THR 12 ASN 13 0.0004

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 -0.0000

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0003

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 -0.0002

ARG 19 PHE 20 -0.0003

PHE 20 ASP 21 0.0190

ASP 21 GLU 22 0.0004

GLU 22 GLU 23 0.0004

GLU 23 PRO 24 -0.0000

PRO 24 MET 25 0.0001

MET 25 GLN 26 0.0001

GLN 26 ALA 27 -0.0004

ALA 27 ILE 28 0.0001

ILE 28 SER 29 0.0001

SER 29 VAL 30 -0.0003

VAL 30 PHE 31 -0.0047

PHE 31 LEU 32 -0.0000

LEU 32 GLY 33 0.0001

GLY 33 LEU 34 0.0003

LEU 34 ALA 35 0.0002

ALA 35 ARG 36 0.0002

ARG 36 ARG 37 0.0001

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 0.0002

ALA 40 GLU 41 -0.0439

GLU 41 PHE 42 0.0002

PHE 42 TYR 43 0.0001

TYR 43 MET 44 -0.0003

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0002

GLY 46 PRO 47 -0.0003

PRO 47 VAL 48 0.0003

VAL 48 TYR 49 0.0000

TYR 49 GLN 50 -0.0001

GLN 50 GLU 51 0.0142

GLU 51 LEU 52 -0.0001

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 0.0002

ASN 54 LEU 55 -0.0000

LEU 55 ARG 56 -0.0001

ARG 56 SER 57 -0.0004

SER 57 MET 58 0.0001

MET 58 ASP 59 0.0001

ASP 59 LEU 60 0.0001

LEU 60 ILE 61 -0.0116

ILE 61 GLY 62 -0.0000

GLY 62 ALA 63 0.0000

ALA 63 GLU 64 0.0002

GLU 64 PHE 65 0.0001

PHE 65 GLU 66 0.0002

GLU 66 THR 67 -0.0002

THR 67 GLU 68 0.0001

GLU 68 VAL 69 0.0003

VAL 69 TYR 70 0.0002

TYR 70 ILE 71 0.0086

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0002

SER 73 PRO 74 0.0000

PRO 74 ARG 75 -0.0000

ARG 75 ARG 76 -0.0001

ARG 76 PHE 77 -0.0003

PHE 77 SER 78 0.0001

SER 78 MET 79 0.0001

MET 79 THR 80 -0.0003

THR 80 ILE 81 -0.0883

ILE 81 PRO 82 -0.0002

PRO 82 SER 83 -0.0002

SER 83 GLU 84 0.0004

GLU 84 VAL 85 -0.0002

VAL 85 LEU 86 0.0002

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 -0.0004

GLU 88 PHE 89 0.0001

PHE 89 ILE 90 0.0000

ILE 90 GLU 91 -0.0099

GLU 91 GLU 92 0.0000

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 -0.0001

ARG 94 THR 95 -0.0000

THR 95 ARG 96 -0.0002

ARG 96 ILE 97 0.0005

ILE 97 GLN 98 0.0003

GLN 98 GLU 131 0.0004

GLU 131 ALA 132 0.0001

ALA 132 MET 133 -0.0002

MET 133 ARG 134 -0.0000

ARG 134 ARG 135 0.0003

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 0.0002

ILE 137 LEU 138 -0.0003

LEU 138 ASP 139 0.0003

ASP 139 SER 140 0.0004

SER 140 ARG 141 0.0169

ARG 141 GLU 142 -0.0001

GLU 142 ASP 143 0.0004

ASP 143 ILE 144 0.0004

ILE 144 ASP 145 0.0001

ASP 145 VAL 146 -0.0003

VAL 146 VAL 147 0.0000

VAL 147 LEU 148 -0.0003

LEU 148 LEU 149 0.0001

LEU 149 ALA 150 0.0001

ALA 150 TYR 151 0.0194

TYR 151 GLU 152 0.0004

GLU 152 LEU 153 -0.0003

LEU 153 ASP 154 0.0004

ASP 154 ALA 155 -0.0002

ALA 155 THR 156 0.0003

THR 156 LEU 157 -0.0002

LEU 157 VAL 158 0.0002

VAL 158 SER 159 -0.0001

SER 159 ALA 160 0.0002

ALA 160 ASP 161 -0.0156

ASP 161 GLU 162 0.0003

GLU 162 GLY 163 -0.0003

GLY 163 MET 164 -0.0004

MET 164 ARG 165 0.0001

ARG 165 LYS 166 0.0001

LYS 166 PHE 167 -0.0002

PHE 167 ALA 168 0.0003

ALA 168 GLU 169 -0.0003

GLU 169 ARG 170 0.0004

ARG 170 ILE 171 -0.0096

ILE 171 GLY 172 -0.0003

GLY 172 ILE 173 0.0002

ILE 173 LYS 174 -0.0004

LYS 174 LEU 175 -0.0001

LEU 175 VAL 176 0.0004

VAL 176 ASN 177 -0.0002

ASN 177 PRO 178 0.0002

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 -0.0004

TYR 180 LEU 181 -0.0051

LEU 181 ARG 182 -0.0001

ARG 182 GLY 183 0.0000

GLY 183 VAL 184 -0.0002

VAL 184 MET 185 -0.0004

MET 185 GLN 186 -0.0003

GLN 186 ASN 187 0.0001

ASN 187 LEU 188 -0.0002

LEU 188 ALA 189 -0.0001

ALA 189 ARG 2 -0.0303

ARG 2 ARG 3 -0.0001

ARG 3 PHE 4 0.0004

PHE 4 VAL 5 -0.0001

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 0.0002

THR 8 SER 9 0.0003

SER 9 VAL 10 -0.0000

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 0.0016

THR 12 ASN 13 0.0003

ASN 13 PRO 14 -0.0004

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 0.0001

TYR 17 LEU 18 0.0001

LEU 18 ARG 19 0.0002

ARG 19 PHE 20 0.0000

PHE 20 ASP 21 -0.0001

ASP 21 GLU 22 -0.0018

GLU 22 GLU 23 0.0003

GLU 23 PRO 24 0.0001

PRO 24 MET 25 -0.0003

MET 25 GLN 26 0.0002

GLN 26 ALA 27 -0.0002

ALA 27 ILE 28 0.0003

ILE 28 SER 29 0.0001

SER 29 VAL 30 0.0004

VAL 30 PHE 31 0.0000

PHE 31 LEU 32 -0.0067

LEU 32 GLY 33 0.0000

GLY 33 LEU 34 -0.0003

LEU 34 ALA 35 0.0001

ALA 35 ARG 36 -0.0001

ARG 36 ARG 37 -0.0001

ARG 37 ALA 38 -0.0001

ALA 38 ASP 39 -0.0001

ASP 39 ALA 40 -0.0001

ALA 40 GLU 41 0.0003

GLU 41 PHE 42 0.0039

PHE 42 TYR 43 0.0001

TYR 43 MET 44 -0.0000

MET 44 PRO 45 0.0003

PRO 45 GLY 46 0.0003

GLY 46 PRO 47 0.0004

PRO 47 VAL 48 0.0002

VAL 48 TYR 49 -0.0000

TYR 49 GLN 50 0.0001

GLN 50 GLU 51 0.0003

GLU 51 LEU 52 0.0053

LEU 52 CYS 53 0.0001

CYS 53 ASN 54 -0.0001

ASN 54 LEU 55 -0.0002

LEU 55 ARG 56 0.0001

ARG 56 SER 57 -0.0001

SER 57 MET 58 0.0004

MET 58 ASP 59 0.0000

ASP 59 LEU 60 0.0003

LEU 60 ILE 61 0.0001

ILE 61 GLY 62 -0.0243

GLY 62 ALA 63 0.0001

ALA 63 GLU 64 0.0000

GLU 64 PHE 65 0.0005

PHE 65 GLU 66 0.0001

GLU 66 THR 67 0.0003

THR 67 GLU 68 0.0004

GLU 68 VAL 69 -0.0002

VAL 69 TYR 70 -0.0004

TYR 70 ILE 71 -0.0001

ILE 71 ARG 72 -0.0210

ARG 72 SER 73 0.0004

SER 73 PRO 74 -0.0000

PRO 74 ARG 75 -0.0004

ARG 75 ARG 76 0.0000

ARG 76 PHE 77 -0.0002

PHE 77 SER 78 0.0000

SER 78 MET 79 -0.0001

MET 79 THR 80 -0.0001

THR 80 ILE 81 -0.0001

ILE 81 PRO 82 0.0302

PRO 82 SER 83 0.0002

SER 83 GLU 84 0.0001

GLU 84 VAL 85 0.0000

VAL 85 LEU 86 0.0002

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 -0.0002

GLU 88 PHE 89 0.0002

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 0.0002

GLU 91 GLU 92 0.0184

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 -0.0000

ARG 94 THR 95 0.0001

THR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0002

ILE 97 GLN 98 -0.0004

GLN 98 GLU 131 -0.0070

GLU 131 ALA 132 0.0001

ALA 132 MET 133 -0.0003

MET 133 ARG 134 -0.0004

ARG 134 ARG 135 0.0001

ARG 135 GLY 136 0.0001

GLY 136 ILE 137 0.0003

ILE 137 LEU 138 -0.0000

LEU 138 ASP 139 0.0001

ASP 139 SER 140 0.0004

SER 140 ARG 141 0.0168

ARG 141 GLU 142 -0.0002

GLU 142 ASP 143 -0.0000

ASP 143 ILE 144 -0.0002

ILE 144 ASP 145 0.0003

ASP 145 VAL 146 -0.0002

VAL 146 VAL 147 -0.0005

VAL 147 LEU 148 -0.0004

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0001

ALA 150 TYR 151 0.0183

TYR 151 GLU 152 -0.0000

GLU 152 LEU 153 -0.0001

LEU 153 ASP 154 0.0003

ASP 154 ALA 155 -0.0001

ALA 155 THR 156 0.0001

THR 156 LEU 157 0.0002

LEU 157 VAL 158 0.0002

VAL 158 SER 159 0.0000

SER 159 ALA 160 0.0001

ALA 160 ASP 161 -0.0275

ASP 161 GLU 162 0.0001

GLU 162 GLY 163 0.0003

GLY 163 MET 164 -0.0001

MET 164 ARG 165 0.0005

ARG 165 LYS 166 0.0001

LYS 166 PHE 167 0.0005

PHE 167 ALA 168 -0.0001

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 -0.0001

ARG 170 ILE 171 0.0005

ILE 171 GLY 172 0.0002

GLY 172 ILE 173 -0.0001

ILE 173 LYS 174 -0.0000

LYS 174 LEU 175 0.0001

LEU 175 VAL 176 -0.0001

VAL 176 ASN 177 -0.0002

ASN 177 PRO 178 0.0002

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 0.0001

TYR 180 LEU 181 0.0373

LEU 181 ARG 182 -0.0002

ARG 182 GLY 183 0.0005

GLY 183 VAL 184 0.0002

VAL 184 MET 185 0.0001

MET 185 GLN 186 0.0002

GLN 186 ASN 187 0.0000

ASN 187 LEU 188 0.0000

LEU 188 ALA 189 0.0003

ALA 189 SER 1 -0.0197

SER 1 ARG 2 0.0002

ARG 2 ARG 3 0.0002

ARG 3 PHE 4 -0.0001

PHE 4 VAL 5 -0.0002

VAL 5 LEU 6 0.0004

LEU 6 ASP 7 0.0000

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0000

SER 9 VAL 10 -0.0004

VAL 10 PHE 11 -0.0077

PHE 11 THR 12 0.0001

THR 12 ASN 13 -0.0003

ASN 13 PRO 14 -0.0001

PRO 14 ASP 15 0.0003

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 -0.0000

TYR 17 LEU 18 -0.0001

LEU 18 ARG 19 -0.0003

ARG 19 PHE 20 -0.0003

PHE 20 ASP 21 -0.0083

ASP 21 GLU 22 -0.0000

GLU 22 GLU 23 0.0005

GLU 23 PRO 24 -0.0001

PRO 24 MET 25 0.0001

MET 25 GLN 26 0.0001

GLN 26 ALA 27 0.0002

ALA 27 ILE 28 -0.0002

ILE 28 SER 29 -0.0001

SER 29 VAL 30 0.0003

VAL 30 PHE 31 -0.0046

PHE 31 LEU 32 -0.0003

LEU 32 GLY 33 0.0004

GLY 33 LEU 34 -0.0000

LEU 34 ALA 35 -0.0001

ALA 35 ARG 36 0.0001

ARG 36 ARG 37 -0.0002

ARG 37 ALA 38 -0.0003

ALA 38 ASP 39 0.0000

ASP 39 ALA 40 0.0002

ALA 40 GLU 41 0.0413

GLU 41 PHE 42 0.0001

PHE 42 TYR 43 0.0001

TYR 43 MET 44 -0.0001

MET 44 PRO 45 -0.0002

PRO 45 GLY 46 0.0001

GLY 46 PRO 47 0.0002

PRO 47 VAL 48 -0.0002

VAL 48 TYR 49 -0.0001

TYR 49 GLN 50 0.0002

GLN 50 GLU 51 -0.0314

GLU 51 LEU 52 0.0001

LEU 52 CYS 53 0.0003

CYS 53 ASN 54 0.0004

ASN 54 LEU 55 0.0002

LEU 55 ARG 56 -0.0002

ARG 56 SER 57 0.0002

SER 57 MET 58 0.0000

MET 58 ASP 59 -0.0001

ASP 59 LEU 60 0.0003

LEU 60 ILE 61 -0.0132

ILE 61 GLY 62 -0.0001

GLY 62 ALA 63 -0.0002

ALA 63 GLU 64 0.0000

GLU 64 PHE 65 0.0001

PHE 65 GLU 66 0.0003

GLU 66 THR 67 -0.0002

THR 67 GLU 68 -0.0000

GLU 68 VAL 69 -0.0003

VAL 69 TYR 70 -0.0001

TYR 70 ILE 71 -0.0003

ILE 71 ARG 72 -0.0003

ARG 72 SER 73 0.0002

SER 73 PRO 74 0.0000

PRO 74 ARG 75 0.0002

ARG 75 ARG 76 -0.0001

ARG 76 PHE 77 0.0003

PHE 77 SER 78 0.0000

SER 78 MET 79 -0.0004

MET 79 THR 80 -0.0001

THR 80 ILE 81 0.0759

ILE 81 PRO 82 0.0003

PRO 82 SER 83 -0.0002

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 0.0002

VAL 85 LEU 86 -0.0002

LEU 86 TYR 87 -0.0003

TYR 87 GLU 88 -0.0000

GLU 88 PHE 89 -0.0003

PHE 89 ILE 90 0.0005

ILE 90 GLU 91 -0.0040

GLU 91 GLU 92 0.0000

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 -0.0000

ARG 94 THR 95 0.0001

THR 95 ARG 96 0.0000

ARG 96 ILE 97 -0.0003

ILE 97 GLN 98 -0.0002

GLN 98 GLU 131 0.0013

GLU 131 ALA 132 -0.0002

ALA 132 MET 133 -0.0002

MET 133 ARG 134 0.0003

ARG 134 ARG 135 -0.0001

ARG 135 GLY 136 -0.0003

GLY 136 ILE 137 -0.0001

ILE 137 LEU 138 -0.0001

LEU 138 ASP 139 0.0003

ASP 139 SER 140 0.0000

SER 140 ARG 141 0.0137

ARG 141 GLU 142 0.0001

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 0.0000

ILE 144 ASP 145 0.0001

ASP 145 VAL 146 0.0003

VAL 146 VAL 147 -0.0002

VAL 147 LEU 148 -0.0002

LEU 148 LEU 149 0.0001

LEU 149 ALA 150 0.0001

ALA 150 TYR 151 -0.0009

TYR 151 GLU 152 -0.0003

GLU 152 LEU 153 -0.0005

LEU 153 ASP 154 -0.0001

ASP 154 ALA 155 -0.0005

ALA 155 THR 156 -0.0001

THR 156 LEU 157 0.0001

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 -0.0001

SER 159 ALA 160 -0.0000

ALA 160 ASP 161 0.0009

ASP 161 GLU 162 -0.0001

GLU 162 GLY 163 -0.0001

GLY 163 MET 164 -0.0001

MET 164 ARG 165 -0.0001

ARG 165 LYS 166 -0.0002

LYS 166 PHE 167 0.0000

PHE 167 ALA 168 -0.0000

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 0.0002

ARG 170 ILE 171 0.0260

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 0.0000

ILE 173 LYS 174 -0.0001

LYS 174 LEU 175 -0.0004

LEU 175 VAL 176 0.0001

VAL 176 ASN 177 -0.0000

ASN 177 PRO 178 -0.0001

PRO 178 ARG 179 -0.0001

ARG 179 TYR 180 0.0002

TYR 180 LEU 181 0.0185

LEU 181 ARG 182 0.0005

ARG 182 GLY 183 0.0002

GLY 183 VAL 184 -0.0002

VAL 184 MET 185 -0.0002

MET 185 GLN 186 0.0000

GLN 186 ASN 187 0.0000

ASN 187 LEU 188 0.0001

LEU 188 ALA 189 -0.0001

ALA 189 SER 1 -0.0483

SER 1 ARG 2 0.0002

ARG 2 ARG 3 -0.0000

ARG 3 PHE 4 -0.0000

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 -0.0000

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 0.0003

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0023

PHE 11 THR 12 -0.0001

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 0.0003

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 -0.0001

VAL 16 TYR 17 -0.0002

TYR 17 LEU 18 0.0003

LEU 18 ARG 19 0.0002

ARG 19 PHE 20 0.0002

PHE 20 ASP 21 0.0201

ASP 21 GLU 22 0.0000

GLU 22 GLU 23 0.0002

GLU 23 PRO 24 0.0001

PRO 24 MET 25 -0.0001

MET 25 GLN 26 0.0000

GLN 26 ALA 27 0.0006

ALA 27 ILE 28 0.0000

ILE 28 SER 29 -0.0000

SER 29 VAL 30 -0.0001

VAL 30 PHE 31 0.0034

PHE 31 LEU 32 -0.0001

LEU 32 GLY 33 0.0000

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 -0.0001

ALA 35 ARG 36 0.0001

ARG 36 ARG 37 0.0000

ARG 37 ALA 38 0.0000

ALA 38 ASP 39 -0.0003

ASP 39 ALA 40 0.0001

ALA 40 GLU 41 -0.0366

GLU 41 PHE 42 0.0002

PHE 42 TYR 43 -0.0002

TYR 43 MET 44 0.0004

MET 44 PRO 45 0.0001

PRO 45 GLY 46 0.0001

GLY 46 PRO 47 0.0000

PRO 47 VAL 48 -0.0001

VAL 48 TYR 49 0.0001

TYR 49 GLN 50 -0.0001

GLN 50 GLU 51 0.0238

GLU 51 LEU 52 0.0002

LEU 52 CYS 53 -0.0003

CYS 53 ASN 54 0.0001

ASN 54 LEU 55 0.0000

LEU 55 ARG 56 0.0000

ARG 56 SER 57 0.0002

SER 57 MET 58 0.0001

MET 58 ASP 59 -0.0002

ASP 59 LEU 60 -0.0000

LEU 60 ILE 61 -0.0091

ILE 61 GLY 62 -0.0002

GLY 62 ALA 63 0.0000

ALA 63 GLU 64 -0.0002

GLU 64 PHE 65 -0.0000

PHE 65 GLU 66 -0.0002

GLU 66 THR 67 -0.0001

THR 67 GLU 68 0.0002

GLU 68 VAL 69 0.0001

VAL 69 TYR 70 -0.0001

TYR 70 ILE 71 0.0082

ILE 71 ARG 72 -0.0003

ARG 72 SER 73 -0.0001

SER 73 PRO 74 0.0002

PRO 74 ARG 75 -0.0001

ARG 75 ARG 76 0.0003

ARG 76 PHE 77 -0.0002

PHE 77 SER 78 0.0004

SER 78 MET 79 -0.0002

MET 79 THR 80 -0.0003

THR 80 ILE 81 -0.0478

ILE 81 PRO 82 0.0002

PRO 82 SER 83 -0.0000

SER 83 GLU 84 -0.0002

GLU 84 VAL 85 0.0003

VAL 85 LEU 86 0.0002

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 -0.0003

GLU 88 PHE 89 -0.0002

PHE 89 ILE 90 -0.0000

ILE 90 GLU 91 -0.0082

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 -0.0003

ARG 94 THR 95 0.0002

THR 95 ARG 96 0.0002

ARG 96 ILE 97 0.0002

ILE 97 GLN 98 -0.0001

GLN 98 GLU 131 -0.0002

GLU 131 ALA 132 0.0001

ALA 132 MET 133 0.0001

MET 133 ARG 134 -0.0001

ARG 134 ARG 135 -0.0002

ARG 135 GLY 136 0.0000

GLY 136 ILE 137 -0.0004

ILE 137 LEU 138 0.0002

LEU 138 ASP 139 0.0003

ASP 139 SER 140 0.0003

SER 140 ARG 141 0.0150

ARG 141 GLU 142 -0.0000

GLU 142 ASP 143 -0.0002

ASP 143 ILE 144 0.0000

ILE 144 ASP 145 -0.0001

ASP 145 VAL 146 -0.0001

VAL 146 VAL 147 0.0000

VAL 147 LEU 148 -0.0003

LEU 148 LEU 149 0.0002

LEU 149 ALA 150 0.0002

ALA 150 TYR 151 0.0068

TYR 151 GLU 152 0.0001

GLU 152 LEU 153 0.0002

LEU 153 ASP 154 0.0004

ASP 154 ALA 155 0.0002

ALA 155 THR 156 -0.0002

THR 156 LEU 157 -0.0001

LEU 157 VAL 158 0.0001

VAL 158 SER 159 -0.0001

SER 159 ALA 160 -0.0003

ALA 160 ASP 161 -0.0073

ASP 161 GLU 162 0.0002

GLU 162 GLY 163 0.0002

GLY 163 MET 164 -0.0002

MET 164 ARG 165 -0.0001

ARG 165 LYS 166 -0.0001

LYS 166 PHE 167 0.0001

PHE 167 ALA 168 0.0003

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 0.0004

ARG 170 ILE 171 -0.0081

ILE 171 GLY 172 0.0003

GLY 172 ILE 173 0.0001

ILE 173 LYS 174 0.0001

LYS 174 LEU 175 -0.0002

LEU 175 VAL 176 -0.0001

VAL 176 ASN 177 0.0004

ASN 177 PRO 178 -0.0001

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 0.0002

TYR 180 LEU 181 -0.0029

LEU 181 ARG 182 -0.0001

ARG 182 GLY 183 0.0002

GLY 183 VAL 184 -0.0002

VAL 184 MET 185 0.0001

MET 185 GLN 186 -0.0003

GLN 186 ASN 187 -0.0002

ASN 187 LEU 188 0.0003

LEU 188 ALA 189 0.0002

ALA 189 SER 1 -0.0202

SER 1 ARG 2 0.0002

ARG 2 ARG 3 0.0002

ARG 3 PHE 4 -0.0001

PHE 4 VAL 5 -0.0001

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 0.0000

ASP 7 THR 8 0.0003

THR 8 SER 9 0.0001

SER 9 VAL 10 0.0001

VAL 10 PHE 11 0.0264

PHE 11 THR 12 0.0001

THR 12 ASN 13 0.0001

ASN 13 PRO 14 -0.0003

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 -0.0004

TYR 17 LEU 18 0.0002

LEU 18 ARG 19 -0.0003

ARG 19 PHE 20 0.0000

PHE 20 ASP 21 -0.0017

ASP 21 GLU 22 0.0001

GLU 22 GLU 23 0.0003

GLU 23 PRO 24 0.0000

PRO 24 MET 25 -0.0002

MET 25 GLN 26 0.0000

GLN 26 ALA 27 -0.0000

ALA 27 ILE 28 -0.0001

ILE 28 SER 29 -0.0001

SER 29 VAL 30 -0.0001

VAL 30 PHE 31 -0.0039

PHE 31 LEU 32 -0.0001

LEU 32 GLY 33 0.0001

GLY 33 LEU 34 0.0000

LEU 34 ALA 35 -0.0001

ALA 35 ARG 36 0.0003

ARG 36 ARG 37 0.0001

ARG 37 ALA 38 0.0001

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 -0.0006

ALA 40 GLU 41 0.0061

GLU 41 PHE 42 -0.0001

PHE 42 TYR 43 -0.0000

TYR 43 MET 44 -0.0003

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0001

GLY 46 PRO 47 0.0002

PRO 47 VAL 48 -0.0002

VAL 48 TYR 49 0.0000

TYR 49 GLN 50 -0.0002

GLN 50 GLU 51 -0.0199

GLU 51 LEU 52 -0.0002

LEU 52 CYS 53 0.0000

CYS 53 ASN 54 0.0001

ASN 54 LEU 55 -0.0004

LEU 55 ARG 56 -0.0003

ARG 56 SER 57 0.0002

SER 57 MET 58 -0.0004

MET 58 ASP 59 -0.0000

ASP 59 LEU 60 -0.0003

LEU 60 ILE 61 0.0103

ILE 61 GLY 62 0.0001

GLY 62 ALA 63 -0.0000

ALA 63 GLU 64 0.0002

GLU 64 PHE 65 0.0000

PHE 65 GLU 66 0.0002

GLU 66 THR 67 -0.0001

THR 67 GLU 68 -0.0000

GLU 68 VAL 69 0.0001

VAL 69 TYR 70 -0.0001

TYR 70 ILE 71 -0.0095

ILE 71 ARG 72 -0.0002

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 -0.0000

ARG 75 ARG 76 0.0003

ARG 76 PHE 77 -0.0003

PHE 77 SER 78 -0.0003

SER 78 MET 79 0.0000

MET 79 THR 80 -0.0000

THR 80 ILE 81 -0.0236

ILE 81 PRO 82 -0.0003

PRO 82 SER 83 0.0001

SER 83 GLU 84 -0.0001

GLU 84 VAL 85 0.0003

VAL 85 LEU 86 -0.0000

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 0.0001

GLU 88 PHE 89 -0.0001

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 0.0007

GLU 91 GLU 92 0.0000

GLU 92 VAL 93 -0.0000

VAL 93 ARG 94 0.0002

ARG 94 THR 95 -0.0001

THR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0002

ILE 97 GLN 98 -0.0002

GLN 98 GLU 131 -0.0048

GLU 131 ALA 132 -0.0001

ALA 132 MET 133 0.0001

MET 133 ARG 134 0.0003

ARG 134 ARG 135 0.0003

ARG 135 GLY 136 -0.0000

GLY 136 ILE 137 0.0002

ILE 137 LEU 138 0.0002

LEU 138 ASP 139 -0.0001

ASP 139 SER 140 0.0002

SER 140 ARG 141 0.0140

ARG 141 GLU 142 0.0002

GLU 142 ASP 143 -0.0003

ASP 143 ILE 144 -0.0003

ILE 144 ASP 145 -0.0001

ASP 145 VAL 146 0.0001

VAL 146 VAL 147 0.0001

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 0.0000

ALA 150 TYR 151 0.0194

TYR 151 GLU 152 0.0000

GLU 152 LEU 153 -0.0003

LEU 153 ASP 154 -0.0001

ASP 154 ALA 155 -0.0001

ALA 155 THR 156 0.0003

THR 156 LEU 157 -0.0004

LEU 157 VAL 158 0.0000

VAL 158 SER 159 -0.0002

SER 159 ALA 160 0.0001

ALA 160 ASP 161 -0.0009

ASP 161 GLU 162 -0.0002

GLU 162 GLY 163 -0.0005

GLY 163 MET 164 0.0001

MET 164 ARG 165 0.0001

ARG 165 LYS 166 -0.0003

LYS 166 PHE 167 0.0004

PHE 167 ALA 168 0.0002

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 -0.0001

ARG 170 ILE 171 0.0029

ILE 171 GLY 172 0.0003

GLY 172 ILE 173 -0.0003

ILE 173 LYS 174 0.0002

LYS 174 LEU 175 0.0001

LEU 175 VAL 176 0.0000

VAL 176 ASN 177 -0.0001

ASN 177 PRO 178 -0.0001

PRO 178 ARG 179 -0.0003

ARG 179 TYR 180 -0.0001

TYR 180 LEU 181 -0.0131

LEU 181 ARG 182 0.0001

ARG 182 GLY 183 0.0000

GLY 183 VAL 184 0.0002

VAL 184 MET 185 0.0005

MET 185 GLN 186 -0.0001

GLN 186 ASN 187 -0.0004

ASN 187 LEU 188 -0.0000

LEU 188 ALA 189 0.0004

ALA 189 SER 1 -0.0842

SER 1 ARG 2 0.0001

ARG 2 ARG 3 -0.0002

ARG 3 PHE 4 0.0002

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 -0.0005

LEU 6 ASP 7 0.0001

ASP 7 THR 8 0.0001

THR 8 SER 9 0.0001

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0006

PHE 11 THR 12 -0.0004

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 0.0000

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0004

TYR 17 LEU 18 0.0001

LEU 18 ARG 19 -0.0001

ARG 19 PHE 20 -0.0001

PHE 20 ASP 21 0.0111

ASP 21 GLU 22 -0.0000

GLU 22 GLU 23 -0.0000

GLU 23 PRO 24 0.0000

PRO 24 MET 25 0.0002

MET 25 GLN 26 -0.0001

GLN 26 ALA 27 -0.0004

ALA 27 ILE 28 -0.0001

ILE 28 SER 29 -0.0003

SER 29 VAL 30 -0.0000

VAL 30 PHE 31 -0.0056

PHE 31 LEU 32 -0.0001

LEU 32 GLY 33 0.0000

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 0.0004

ALA 35 ARG 36 -0.0002

ARG 36 ARG 37 -0.0002

ARG 37 ALA 38 0.0002

ALA 38 ASP 39 0.0003

ASP 39 ALA 40 0.0001

ALA 40 GLU 41 -0.0073

GLU 41 PHE 42 -0.0000

PHE 42 TYR 43 0.0001

TYR 43 MET 44 0.0004

MET 44 PRO 45 0.0002

PRO 45 GLY 46 0.0000

GLY 46 PRO 47 -0.0000

PRO 47 VAL 48 -0.0003

VAL 48 TYR 49 0.0002

TYR 49 GLN 50 -0.0001

GLN 50 GLU 51 -0.0106

GLU 51 LEU 52 -0.0001

LEU 52 CYS 53 0.0002

CYS 53 ASN 54 0.0000

ASN 54 LEU 55 0.0000

LEU 55 ARG 56 0.0001

ARG 56 SER 57 0.0003

SER 57 MET 58 -0.0003

MET 58 ASP 59 0.0001

ASP 59 LEU 60 -0.0000

LEU 60 ILE 61 -0.0060

ILE 61 GLY 62 -0.0001

GLY 62 ALA 63 -0.0001

ALA 63 GLU 64 -0.0001

GLU 64 PHE 65 -0.0002

PHE 65 GLU 66 -0.0002

GLU 66 THR 67 0.0000

THR 67 GLU 68 0.0002

GLU 68 VAL 69 -0.0001

VAL 69 TYR 70 -0.0004

TYR 70 ILE 71 -0.0199

ILE 71 ARG 72 -0.0000

ARG 72 SER 73 0.0004

SER 73 PRO 74 -0.0001

PRO 74 ARG 75 0.0001

ARG 75 ARG 76 0.0002

ARG 76 PHE 77 0.0002

PHE 77 SER 78 0.0002

SER 78 MET 79 0.0002

MET 79 THR 80 0.0003

THR 80 ILE 81 0.0492

ILE 81 PRO 82 0.0000

PRO 82 SER 83 -0.0001

SER 83 GLU 84 0.0000

GLU 84 VAL 85 0.0004

VAL 85 LEU 86 0.0005

LEU 86 TYR 87 -0.0003

TYR 87 GLU 88 -0.0000

GLU 88 PHE 89 -0.0001

PHE 89 ILE 90 0.0000

ILE 90 GLU 91 -0.0112

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 0.0001

ARG 94 THR 95 -0.0002

THR 95 ARG 96 0.0004

ARG 96 ILE 97 -0.0003

ILE 97 GLN 98 0.0001

GLN 98 GLU 131 0.0144

GLU 131 ALA 132 0.0001

ALA 132 MET 133 -0.0000

MET 133 ARG 134 -0.0003

ARG 134 ARG 135 -0.0000

ARG 135 GLY 136 -0.0003

GLY 136 ILE 137 -0.0003

ILE 137 LEU 138 0.0001

LEU 138 ASP 139 0.0000

ASP 139 SER 140 0.0002

SER 140 ARG 141 0.0155

ARG 141 GLU 142 0.0001

GLU 142 ASP 143 -0.0000

ASP 143 ILE 144 -0.0004

ILE 144 ASP 145 -0.0004

ASP 145 VAL 146 0.0001

VAL 146 VAL 147 -0.0003

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 -0.0000

LEU 149 ALA 150 -0.0002

ALA 150 TYR 151 -0.0083

TYR 151 GLU 152 0.0000

GLU 152 LEU 153 0.0002

LEU 153 ASP 154 0.0000

ASP 154 ALA 155 -0.0000

ALA 155 THR 156 -0.0003

THR 156 LEU 157 -0.0002

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 0.0005

SER 159 ALA 160 -0.0001

ALA 160 ASP 161 -0.0138

ASP 161 GLU 162 0.0001

GLU 162 GLY 163 0.0002

GLY 163 MET 164 -0.0003

MET 164 ARG 165 -0.0003

ARG 165 LYS 166 -0.0001

LYS 166 PHE 167 0.0001

PHE 167 ALA 168 -0.0002

ALA 168 GLU 169 -0.0001

GLU 169 ARG 170 -0.0000

ARG 170 ILE 171 0.0140

ILE 171 GLY 172 -0.0000

GLY 172 ILE 173 0.0001

ILE 173 LYS 174 -0.0004

LYS 174 LEU 175 0.0002

LEU 175 VAL 176 0.0000

VAL 176 ASN 177 -0.0000

ASN 177 PRO 178 0.0000

PRO 178 ARG 179 -0.0000

ARG 179 TYR 180 0.0005

TYR 180 LEU 181 0.0240

LEU 181 ARG 182 0.0004

ARG 182 GLY 183 -0.0001

GLY 183 VAL 184 0.0001

VAL 184 MET 185 -0.0001

MET 185 GLN 186 -0.0002

GLN 186 ASN 187 0.0001

ASN 187 LEU 188 -0.0001

LEU 188 ALA 189 -0.0002

ALA 189 SER 1 -0.0313

SER 1 ARG 2 -0.0000

ARG 2 ARG 3 -0.0001

ARG 3 PHE 4 0.0000

PHE 4 VAL 5 -0.0000

VAL 5 LEU 6 0.0000

LEU 6 ASP 7 0.0000

ASP 7 THR 8 -0.0000

THR 8 SER 9 -0.0001

SER 9 VAL 10 0.0000

VAL 10 PHE 11 0.0234

PHE 11 THR 12 0.0003

THR 12 ASN 13 -0.0002

ASN 13 PRO 14 -0.0002

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0003

TYR 17 LEU 18 0.0001

LEU 18 ARG 19 0.0001

ARG 19 PHE 20 0.0004

PHE 20 ASP 21 0.0231

ASP 21 GLU 22 0.0001

GLU 22 GLU 23 0.0001

GLU 23 PRO 24 0.0003

PRO 24 MET 25 0.0003

MET 25 GLN 26 0.0002

GLN 26 ALA 27 -0.0003

ALA 27 ILE 28 0.0002

ILE 28 SER 29 -0.0002

SER 29 VAL 30 -0.0001

VAL 30 PHE 31 -0.0004

PHE 31 LEU 32 -0.0003

LEU 32 GLY 33 -0.0000

GLY 33 LEU 34 0.0001

LEU 34 ALA 35 0.0000

ALA 35 ARG 36 -0.0001

ARG 36 ARG 37 -0.0003

ARG 37 ALA 38 -0.0002

ALA 38 ASP 39 0.0001

ASP 39 ALA 40 -0.0000

ALA 40 GLU 41 -0.0432

GLU 41 PHE 42 0.0002

PHE 42 TYR 43 0.0003

TYR 43 MET 44 -0.0002

MET 44 PRO 45 0.0003

PRO 45 GLY 46 0.0001

GLY 46 PRO 47 0.0002

PRO 47 VAL 48 0.0001

VAL 48 TYR 49 0.0001

TYR 49 GLN 50 -0.0003

GLN 50 GLU 51 0.0109

GLU 51 LEU 52 -0.0004

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 0.0002

ASN 54 LEU 55 0.0001

LEU 55 ARG 56 0.0003

ARG 56 SER 57 -0.0003

SER 57 MET 58 -0.0001

MET 58 ASP 59 -0.0001

ASP 59 LEU 60 0.0002

LEU 60 ILE 61 -0.0214

ILE 61 GLY 62 -0.0001

GLY 62 ALA 63 -0.0002

ALA 63 GLU 64 -0.0001

GLU 64 PHE 65 0.0002

PHE 65 GLU 66 -0.0001

GLU 66 THR 67 -0.0002

THR 67 GLU 68 -0.0000

GLU 68 VAL 69 0.0004

VAL 69 TYR 70 -0.0001

TYR 70 ILE 71 0.0078

ILE 71 ARG 72 0.0001

ARG 72 SER 73 0.0001

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 0.0004

ARG 75 ARG 76 0.0000

ARG 76 PHE 77 -0.0002

PHE 77 SER 78 0.0002

SER 78 MET 79 0.0003

MET 79 THR 80 0.0002

THR 80 ILE 81 -0.0971

ILE 81 PRO 82 -0.0003

PRO 82 SER 83 -0.0002

SER 83 GLU 84 0.0002

GLU 84 VAL 85 -0.0002

VAL 85 LEU 86 -0.0001

LEU 86 TYR 87 0.0000

TYR 87 GLU 88 -0.0000

GLU 88 PHE 89 0.0003

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 -0.0081

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 0.0001

ARG 94 THR 95 0.0000

THR 95 ARG 96 -0.0003

ARG 96 ILE 97 -0.0004

ILE 97 GLN 98 0.0002

GLN 98 GLU 131 -0.0001

GLU 131 ALA 132 0.0000

ALA 132 MET 133 0.0000

MET 133 ARG 134 0.0002

ARG 134 ARG 135 -0.0004

ARG 135 GLY 136 -0.0000

GLY 136 ILE 137 0.0003

ILE 137 LEU 138 -0.0001

LEU 138 ASP 139 0.0001

ASP 139 SER 140 0.0000

SER 140 ARG 141 0.0135

ARG 141 GLU 142 0.0001

GLU 142 ASP 143 -0.0002

ASP 143 ILE 144 -0.0001

ILE 144 ASP 145 0.0002

ASP 145 VAL 146 0.0002

VAL 146 VAL 147 0.0003

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0000

ALA 150 TYR 151 0.0165

TYR 151 GLU 152 -0.0003

GLU 152 LEU 153 -0.0002

LEU 153 ASP 154 0.0000

ASP 154 ALA 155 -0.0001

ALA 155 THR 156 0.0002

THR 156 LEU 157 0.0000

LEU 157 VAL 158 -0.0000

VAL 158 SER 159 -0.0002

SER 159 ALA 160 0.0000

ALA 160 ASP 161 -0.0109

ASP 161 GLU 162 0.0002

GLU 162 GLY 163 -0.0000

GLY 163 MET 164 -0.0001

MET 164 ARG 165 0.0002

ARG 165 LYS 166 0.0002

LYS 166 PHE 167 0.0002

PHE 167 ALA 168 -0.0001

ALA 168 GLU 169 0.0002

GLU 169 ARG 170 -0.0003

ARG 170 ILE 171 -0.0194

ILE 171 GLY 172 -0.0000

GLY 172 ILE 173 -0.0001

ILE 173 LYS 174 0.0000

LYS 174 LEU 175 0.0002

LEU 175 VAL 176 -0.0001

VAL 176 ASN 177 0.0001

ASN 177 PRO 178 0.0000

PRO 178 ARG 179 -0.0003

ARG 179 TYR 180 0.0001

TYR 180 LEU 181 -0.0051

LEU 181 ARG 182 0.0002

ARG 182 GLY 183 -0.0000

GLY 183 VAL 184 -0.0004

VAL 184 MET 185 -0.0002

MET 185 GLN 186 0.0003

GLN 186 ASN 187 0.0002

ASN 187 LEU 188 -0.0003

LEU 188 ALA 189 -0.0001

ALA 189 ARG 2 -0.0278

ARG 2 ARG 3 -0.0002

ARG 3 PHE 4 -0.0001

PHE 4 VAL 5 -0.0003

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 -0.0003

THR 8 SER 9 -0.0001

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0003

PHE 11 THR 12 0.0046

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 0.0003

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 0.0002

TYR 17 LEU 18 0.0004

LEU 18 ARG 19 -0.0002

ARG 19 PHE 20 0.0000

PHE 20 ASP 21 -0.0000

ASP 21 GLU 22 -0.0005

GLU 22 GLU 23 0.0000

GLU 23 PRO 24 -0.0002

PRO 24 MET 25 -0.0002

MET 25 GLN 26 0.0005

GLN 26 ALA 27 -0.0005

ALA 27 ILE 28 0.0003

ILE 28 SER 29 0.0003

SER 29 VAL 30 0.0000

VAL 30 PHE 31 0.0000

PHE 31 LEU 32 -0.0057

LEU 32 GLY 33 0.0004

GLY 33 LEU 34 -0.0001

LEU 34 ALA 35 -0.0004

ALA 35 ARG 36 -0.0001

ARG 36 ARG 37 -0.0002

ARG 37 ALA 38 -0.0000

ALA 38 ASP 39 -0.0001

ASP 39 ALA 40 0.0002

ALA 40 GLU 41 0.0001

GLU 41 PHE 42 0.0018

PHE 42 TYR 43 -0.0003

TYR 43 MET 44 -0.0003

MET 44 PRO 45 0.0001

PRO 45 GLY 46 -0.0001

GLY 46 PRO 47 -0.0002

PRO 47 VAL 48 -0.0000

VAL 48 TYR 49 -0.0004

TYR 49 GLN 50 0.0002

GLN 50 GLU 51 -0.0002

GLU 51 LEU 52 0.0040

LEU 52 CYS 53 -0.0001

CYS 53 ASN 54 -0.0002

ASN 54 LEU 55 -0.0001

LEU 55 ARG 56 -0.0001

ARG 56 SER 57 0.0000

SER 57 MET 58 0.0001

MET 58 ASP 59 0.0000

ASP 59 LEU 60 -0.0000

LEU 60 ILE 61 -0.0001

ILE 61 GLY 62 -0.0197

GLY 62 ALA 63 0.0002

ALA 63 GLU 64 -0.0002

GLU 64 PHE 65 0.0002

PHE 65 GLU 66 -0.0002

GLU 66 THR 67 0.0002

THR 67 GLU 68 0.0000

GLU 68 VAL 69 0.0003

VAL 69 TYR 70 0.0002

TYR 70 ILE 71 0.0002

ILE 71 ARG 72 -0.0187

ARG 72 SER 73 -0.0001

SER 73 PRO 74 0.0002

PRO 74 ARG 75 -0.0001

ARG 75 ARG 76 -0.0001

ARG 76 PHE 77 0.0001

PHE 77 SER 78 0.0002

SER 78 MET 79 0.0000

MET 79 THR 80 -0.0001

THR 80 ILE 81 0.0001

ILE 81 PRO 82 0.0247

PRO 82 SER 83 -0.0000

SER 83 GLU 84 -0.0004

GLU 84 VAL 85 0.0001

VAL 85 LEU 86 -0.0000

LEU 86 TYR 87 -0.0001

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 -0.0004

PHE 89 ILE 90 -0.0001

ILE 90 GLU 91 0.0000

GLU 91 GLU 92 0.0291

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 0.0001

ARG 94 THR 95 0.0001

THR 95 ARG 96 0.0001

ARG 96 ILE 97 0.0004

ILE 97 GLN 98 -0.0001

GLN 98 GLU 131 -0.0085

GLU 131 ALA 132 -0.0002

ALA 132 MET 133 0.0001

MET 133 ARG 134 0.0001

ARG 134 ARG 135 0.0001

ARG 135 GLY 136 -0.0003

GLY 136 ILE 137 0.0002

ILE 137 LEU 138 -0.0001

LEU 138 ASP 139 0.0000

ASP 139 SER 140 -0.0003

SER 140 ARG 141 0.0111

ARG 141 GLU 142 0.0002

GLU 142 ASP 143 0.0001

ASP 143 ILE 144 0.0000

ILE 144 ASP 145 0.0000

ASP 145 VAL 146 0.0000

VAL 146 VAL 147 -0.0000

VAL 147 LEU 148 0.0003

LEU 148 LEU 149 -0.0002

LEU 149 ALA 150 -0.0003

ALA 150 TYR 151 0.0204

TYR 151 GLU 152 -0.0002

GLU 152 LEU 153 0.0002

LEU 153 ASP 154 -0.0003

ASP 154 ALA 155 0.0000

ALA 155 THR 156 0.0000

THR 156 LEU 157 -0.0004

LEU 157 VAL 158 -0.0002

VAL 158 SER 159 0.0002

SER 159 ALA 160 -0.0001

ALA 160 ASP 161 -0.0384

ASP 161 GLU 162 -0.0001

GLU 162 GLY 163 0.0004

GLY 163 MET 164 -0.0000

MET 164 ARG 165 -0.0001

ARG 165 LYS 166 0.0000

LYS 166 PHE 167 0.0001

PHE 167 ALA 168 0.0002

ALA 168 GLU 169 0.0001

GLU 169 ARG 170 -0.0001

ARG 170 ILE 171 -0.0007

ILE 171 GLY 172 0.0001

GLY 172 ILE 173 -0.0001

ILE 173 LYS 174 0.0002

LYS 174 LEU 175 0.0004

LEU 175 VAL 176 -0.0002

VAL 176 ASN 177 0.0000

ASN 177 PRO 178 0.0004

PRO 178 ARG 179 -0.0003

ARG 179 TYR 180 -0.0003

TYR 180 LEU 181 0.0415

LEU 181 ARG 182 -0.0003

ARG 182 GLY 183 0.0001

GLY 183 VAL 184 0.0003

VAL 184 MET 185 0.0002

MET 185 GLN 186 0.0000

GLN 186 ASN 187 -0.0001

ASN 187 LEU 188 -0.0004

LEU 188 ALA 189 -0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** HYDROLASE 06-MAY-21 7OG5 ***

CA strain for 22121317415457420

--- normal mode 11 ---

Should you encounter any unexpected behaviour,
please let us know.

* HYDROLASE 06-MAY-21 7OG5 *