Should you encounter any unexpected behaviour,
please let us know.

* *

CA strain for 22121317404857062

--- normal mode 7 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
MET 1 ASP 2 0.0001

ASP 2 THR 3 0.0004

THR 3 PHE 4 0.0001

PHE 4 VAL 5 -0.0002

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 0.0000

ASP 7 THR 8 0.0004

THR 8 SER 9 -0.0001

SER 9 VAL 10 0.0002

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 -0.0010

THR 12 ASN 13 0.0002

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 0.0002

ASP 15 VAL 16 -0.0002

VAL 16 TYR 17 0.0005

TYR 17 HIS 18 -0.0000

HIS 18 GLN 19 -0.0003

GLN 19 PHE 20 0.0000

PHE 20 GLU 21 -0.0000

GLU 21 GLU 22 -0.0001

GLU 22 ASP 23 0.0003

ASP 23 GLN 24 -0.0002

GLN 24 LEU 25 0.0002

LEU 25 GLY 26 -0.0002

GLY 26 ALA 27 -0.0004

ALA 27 ILE 28 0.0000

ILE 28 GLU 29 -0.0003

GLU 29 ASN 30 -0.0003

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 -0.0004

ILE 32 SER 33 -0.0001

SER 33 LEU 34 0.0049

LEU 34 ALA 35 0.0002

ALA 35 SER 36 -0.0000

SER 36 HIS 37 -0.0000

HIS 37 THR 38 0.0000

THR 38 ASN 39 0.0002

ASN 39 ALA 40 -0.0001

ALA 40 ASN 41 -0.0001

ASN 41 PHE 42 0.0001

PHE 42 PHE 43 -0.0000

PHE 43 MET 44 -0.0001

MET 44 PRO 45 -0.0036

PRO 45 THR 46 -0.0002

THR 46 SER 47 -0.0001

SER 47 VAL 48 -0.0000

VAL 48 TYR 49 0.0002

TYR 49 TYR 50 0.0001

TYR 50 GLU 51 -0.0004

GLU 51 PHE 52 0.0002

PHE 52 THR 53 -0.0000

THR 53 LYS 54 -0.0002

LYS 54 MET 55 0.0004

MET 55 VAL 56 -0.0026

VAL 56 SER 57 0.0003

SER 57 LEU 58 -0.0000

LEU 58 GLY 59 -0.0002

GLY 59 ASP 60 0.0002

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 0.0002

ALA 62 PRO 63 0.0001

PRO 63 LYS 64 0.0005

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 -0.0002

GLU 66 LEU 67 -0.0016

LEU 67 VAL 68 -0.0001

VAL 68 VAL 69 0.0002

VAL 69 ARG 70 0.0002

ARG 70 ILE 71 -0.0001

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 0.0001

SER 73 PRO 74 -0.0000

PRO 74 ARG 75 -0.0003

ARG 75 LYS 76 -0.0002

LYS 76 TRP 77 0.0002

TRP 77 GLY 78 0.0266

GLY 78 LEU 79 0.0000

LEU 79 MET 80 -0.0001

MET 80 VAL 81 0.0004

VAL 81 PRO 82 -0.0003

PRO 82 ALA 83 0.0002

ALA 83 GLU 84 -0.0001

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 0.0001

LEU 86 TYR 87 0.0003

TYR 87 GLU 88 0.0004

GLU 88 PHE 89 -0.0040

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 -0.0002

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 0.0000

ARG 96 ILE 97 0.0002

ILE 97 ASN 98 0.0002

ASN 98 LYS 99 0.0003

LYS 99 GLY 100 -0.0017

GLY 100 LEU 101 -0.0001

LEU 101 ARG 102 -0.0001

ARG 102 ILE 103 0.0005

ILE 103 ALA 104 -0.0003

ALA 104 GLU 105 -0.0001

GLU 105 GLU 106 0.0000

GLU 106 HIS 107 -0.0001

HIS 107 ARG 125 -0.0005

ARG 125 LEU 126 -0.0002

LEU 126 ARG 127 -0.0001

ARG 127 GLU 128 0.0004

GLU 128 LYS 129 0.0004

LYS 129 TYR 130 0.0001

TYR 130 ARG 131 -0.0001

ARG 131 GLU 132 0.0000

GLU 132 ALA 133 -0.0000

ALA 133 LEU 134 -0.0000

LEU 134 ARG 135 0.0002

ARG 135 ALA 136 0.0009

ALA 136 GLY 137 0.0003

GLY 137 ILE 138 0.0000

ILE 138 ILE 139 0.0002

ILE 139 ASP 140 -0.0000

ASP 140 SER 141 -0.0000

SER 141 LYS 142 0.0001

LYS 142 GLU 143 -0.0004

GLU 143 ASP 144 0.0000

ASP 144 VAL 145 -0.0001

VAL 145 ASP 146 -0.0002

ASP 146 VAL 147 -0.0062

VAL 147 LEU 148 -0.0000

LEU 148 LEU 149 0.0000

LEU 149 LEU 150 -0.0003

LEU 150 SER 151 -0.0001

SER 151 TYR 152 -0.0002

TYR 152 GLU 153 -0.0001

GLU 153 LEU 154 -0.0000

LEU 154 ASP 155 0.0003

ASP 155 ALA 156 0.0003

ALA 156 ILE 157 -0.0000

ILE 157 LEU 158 -0.0011

LEU 158 VAL 159 -0.0002

VAL 159 SER 160 0.0000

SER 160 GLY 161 0.0002

GLY 161 ASP 162 0.0002

ASP 162 GLU 163 0.0000

GLU 163 GLY 164 0.0001

GLY 164 LEU 165 -0.0001

LEU 165 ARG 166 -0.0003

ARG 166 LYS 167 0.0000

LYS 167 TRP 168 -0.0001

TRP 168 ALA 169 0.0031

ALA 169 ASP 170 0.0001

ASP 170 ARG 171 0.0000

ARG 171 VAL 172 0.0002

VAL 172 GLY 173 0.0000

GLY 173 ILE 174 0.0002

ILE 174 LYS 175 0.0000

LYS 175 LEU 176 0.0003

LEU 176 ILE 177 -0.0000

ILE 177 ASP 178 0.0002

ASP 178 PRO 179 -0.0001

PRO 179 LYS 180 0.0040

LYS 180 ASN 181 0.0003

ASN 181 LEU 182 -0.0001

LEU 182 ARG 183 -0.0002

ARG 183 TYR 184 -0.0002

TYR 184 ILE 185 -0.0001

ILE 185 MET 186 0.0000

MET 186 GLU 187 -0.0001

GLU 187 ASN 188 0.0003

ASN 188 LEU 189 -0.0000

LEU 189 THR 190 -0.0003

THR 190 MET 1 -0.0068

MET 1 ASP 2 -0.0002

ASP 2 THR 3 0.0001

THR 3 PHE 4 -0.0002

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 -0.0000

LEU 6 ASP 7 -0.0000

ASP 7 THR 8 0.0002

THR 8 SER 9 -0.0003

SER 9 VAL 10 -0.0001

VAL 10 PHE 11 0.0000

PHE 11 THR 12 -0.0050

THR 12 ASN 13 0.0001

ASN 13 PRO 14 0.0002

PRO 14 ASP 15 0.0002

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0002

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0002

GLN 19 PHE 20 0.0000

PHE 20 GLU 21 0.0001

GLU 21 GLU 22 -0.0003

GLU 22 ASP 23 0.0001

ASP 23 GLN 24 -0.0003

GLN 24 LEU 25 0.0002

LEU 25 GLY 26 -0.0000

GLY 26 ALA 27 0.0002

ALA 27 ILE 28 0.0001

ILE 28 GLU 29 0.0004

GLU 29 ASN 30 -0.0001

ASN 30 PHE 31 0.0004

PHE 31 ILE 32 0.0004

ILE 32 SER 33 0.0001

SER 33 LEU 34 -0.0016

LEU 34 ALA 35 0.0000

ALA 35 SER 36 -0.0001

SER 36 HIS 37 -0.0002

HIS 37 THR 38 -0.0001

THR 38 ASN 39 0.0003

ASN 39 ALA 40 -0.0001

ALA 40 ASN 41 0.0003

ASN 41 PHE 42 -0.0003

PHE 42 PHE 43 0.0004

PHE 43 MET 44 -0.0002

MET 44 PRO 45 -0.0018

PRO 45 THR 46 -0.0000

THR 46 SER 47 -0.0004

SER 47 VAL 48 -0.0003

VAL 48 TYR 49 -0.0004

TYR 49 TYR 50 0.0001

TYR 50 GLU 51 -0.0004

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 -0.0001

THR 53 LYS 54 0.0002

LYS 54 MET 55 -0.0002

MET 55 VAL 56 0.0001

VAL 56 SER 57 -0.0002

SER 57 LEU 58 0.0002

LEU 58 GLY 59 0.0000

GLY 59 ASP 60 -0.0004

ASP 60 LEU 61 0.0002

LEU 61 ALA 62 -0.0003

ALA 62 PRO 63 -0.0001

PRO 63 LYS 64 0.0001

LYS 64 PHE 65 0.0000

PHE 65 GLU 66 -0.0001

GLU 66 LEU 67 -0.0004

LEU 67 VAL 68 -0.0000

VAL 68 VAL 69 0.0002

VAL 69 ARG 70 -0.0001

ARG 70 ILE 71 -0.0000

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0001

SER 73 PRO 74 0.0001

PRO 74 ARG 75 0.0001

ARG 75 LYS 76 -0.0004

LYS 76 TRP 77 0.0002

TRP 77 GLY 78 0.0168

GLY 78 LEU 79 -0.0000

LEU 79 MET 80 0.0002

MET 80 VAL 81 -0.0002

VAL 81 PRO 82 0.0003

PRO 82 ALA 83 -0.0000

ALA 83 GLU 84 -0.0004

GLU 84 PHE 85 0.0003

PHE 85 LEU 86 0.0002

LEU 86 TYR 87 0.0000

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 -0.0036

PHE 89 ILE 90 0.0001

ILE 90 GLU 91 0.0002

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 -0.0001

VAL 93 ARG 94 -0.0000

ARG 94 TYR 95 0.0000

TYR 95 ARG 96 0.0003

ARG 96 ILE 97 0.0001

ILE 97 ASN 98 0.0001

ASN 98 LYS 99 0.0001

LYS 99 GLY 100 0.0035

GLY 100 LEU 101 0.0001

LEU 101 ARG 102 -0.0001

ARG 102 ILE 103 0.0002

ILE 103 ALA 104 -0.0002

ALA 104 GLU 105 -0.0001

GLU 105 GLU 106 -0.0003

GLU 106 HIS 107 0.0001

HIS 107 THR 108 0.0003

THR 108 LEU 126 -0.0012

LEU 126 ARG 127 -0.0002

ARG 127 GLU 128 0.0002

GLU 128 LYS 129 -0.0001

LYS 129 TYR 130 -0.0002

TYR 130 ARG 131 0.0003

ARG 131 GLU 132 0.0000

GLU 132 ALA 133 0.0004

ALA 133 LEU 134 0.0003

LEU 134 ARG 135 0.0002

ARG 135 ALA 136 0.0001

ALA 136 GLY 137 0.0078

GLY 137 ILE 138 0.0004

ILE 138 ILE 139 -0.0002

ILE 139 ASP 140 -0.0001

ASP 140 SER 141 -0.0002

SER 141 LYS 142 0.0001

LYS 142 GLU 143 0.0003

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 0.0004

VAL 145 ASP 146 -0.0000

ASP 146 VAL 147 -0.0001

VAL 147 LEU 148 -0.0018

LEU 148 LEU 149 0.0001

LEU 149 LEU 150 -0.0001

LEU 150 SER 151 0.0001

SER 151 TYR 152 -0.0003

TYR 152 GLU 153 -0.0001

GLU 153 LEU 154 0.0002

LEU 154 ASP 155 -0.0001

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 0.0001

ILE 157 LEU 158 0.0001

LEU 158 VAL 159 -0.0093

VAL 159 SER 160 -0.0003

SER 160 GLY 161 0.0002

GLY 161 ASP 162 0.0002

ASP 162 GLU 163 0.0002

GLU 163 GLY 164 0.0004

GLY 164 LEU 165 -0.0002

LEU 165 ARG 166 -0.0002

ARG 166 LYS 167 -0.0003

LYS 167 TRP 168 -0.0002

TRP 168 ALA 169 -0.0001

ALA 169 ASP 170 0.0126

ASP 170 ARG 171 0.0001

ARG 171 VAL 172 -0.0001

VAL 172 GLY 173 -0.0002

GLY 173 ILE 174 0.0003

ILE 174 LYS 175 -0.0005

LYS 175 LEU 176 0.0002

LEU 176 ILE 177 -0.0004

ILE 177 ASP 178 0.0004

ASP 178 PRO 179 0.0002

PRO 179 LYS 180 -0.0003

LYS 180 ASN 181 0.0164

ASN 181 LEU 182 -0.0002

LEU 182 ARG 183 -0.0002

ARG 183 TYR 184 0.0001

TYR 184 ILE 185 0.0001

ILE 185 MET 186 0.0000

MET 186 GLU 187 -0.0003

GLU 187 ASN 188 -0.0001

ASN 188 LEU 189 0.0002

LEU 189 THR 190 -0.0003

THR 190 LYS 191 0.0004

LYS 191 VAL 192 -0.0008

VAL 192 GLY 193 0.0004

GLY 193 ARG 194 -0.0001

ARG 194 MET 1 0.0048

MET 1 ASP 2 0.0003

ASP 2 THR 3 -0.0000

THR 3 PHE 4 0.0001

PHE 4 VAL 5 -0.0004

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0001

SER 9 VAL 10 0.0000

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 -0.0023

THR 12 ASN 13 0.0002

ASN 13 PRO 14 -0.0003

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 -0.0001

TYR 17 HIS 18 -0.0005

HIS 18 GLN 19 -0.0001

GLN 19 PHE 20 0.0001

PHE 20 GLU 21 0.0004

GLU 21 GLU 22 -0.0002

GLU 22 ASP 23 0.0038

ASP 23 GLN 24 -0.0001

GLN 24 LEU 25 -0.0001

LEU 25 GLY 26 -0.0001

GLY 26 ALA 27 0.0002

ALA 27 ILE 28 0.0001

ILE 28 GLU 29 0.0004

GLU 29 ASN 30 0.0001

ASN 30 PHE 31 -0.0003

PHE 31 ILE 32 -0.0000

ILE 32 SER 33 0.0006

SER 33 LEU 34 -0.0027

LEU 34 ALA 35 0.0000

ALA 35 SER 36 0.0001

SER 36 HIS 37 0.0004

HIS 37 THR 38 -0.0000

THR 38 ASN 39 0.0001

ASN 39 ALA 40 0.0001

ALA 40 ASN 41 -0.0000

ASN 41 PHE 42 0.0001

PHE 42 PHE 43 -0.0002

PHE 43 MET 44 0.0005

MET 44 PRO 45 0.0012

PRO 45 THR 46 -0.0001

THR 46 SER 47 0.0002

SER 47 VAL 48 0.0003

VAL 48 TYR 49 0.0001

TYR 49 TYR 50 -0.0000

TYR 50 GLU 51 -0.0002

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 0.0003

THR 53 LYS 54 -0.0001

LYS 54 MET 55 -0.0000

MET 55 VAL 56 -0.0009

VAL 56 SER 57 -0.0003

SER 57 LEU 58 -0.0003

LEU 58 GLY 59 0.0002

GLY 59 ASP 60 0.0005

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 -0.0002

ALA 62 PRO 63 -0.0000

PRO 63 LYS 64 -0.0001

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 -0.0001

GLU 66 LEU 67 -0.0006

LEU 67 VAL 68 -0.0002

VAL 68 VAL 69 0.0000

VAL 69 ARG 70 0.0000

ARG 70 ILE 71 -0.0003

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 0.0003

SER 73 PRO 74 -0.0001

PRO 74 ARG 75 0.0001

ARG 75 LYS 76 -0.0002

LYS 76 TRP 77 -0.0001

TRP 77 GLY 78 -0.0026

GLY 78 LEU 79 0.0001

LEU 79 MET 80 -0.0003

MET 80 VAL 81 -0.0001

VAL 81 PRO 82 0.0003

PRO 82 ALA 83 0.0004

ALA 83 GLU 84 -0.0003

GLU 84 PHE 85 -0.0003

PHE 85 LEU 86 -0.0001

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 -0.0002

GLU 88 PHE 89 -0.0006

PHE 89 ILE 90 0.0003

ILE 90 GLU 91 0.0002

GLU 91 GLU 92 -0.0002

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 0.0001

ARG 94 TYR 95 -0.0002

TYR 95 ARG 96 -0.0003

ARG 96 ILE 97 -0.0003

ILE 97 ASN 98 -0.0000

ASN 98 LYS 99 -0.0000

LYS 99 GLY 100 0.0002

GLY 100 LEU 101 -0.0004

LEU 101 ARG 102 0.0003

ARG 102 ILE 103 -0.0002

ILE 103 ALA 104 -0.0002

ALA 104 GLU 105 -0.0001

GLU 105 GLU 106 -0.0002

GLU 106 HIS 107 -0.0002

HIS 107 THR 108 -0.0000

THR 108 LEU 126 -0.0005

LEU 126 ARG 127 0.0004

ARG 127 GLU 128 0.0001

GLU 128 LYS 129 0.0004

LYS 129 TYR 130 -0.0004

TYR 130 ARG 131 -0.0002

ARG 131 GLU 132 -0.0001

GLU 132 ALA 133 0.0004

ALA 133 LEU 134 -0.0002

LEU 134 ARG 135 0.0003

ARG 135 ALA 136 -0.0002

ALA 136 GLY 137 0.0015

GLY 137 ILE 138 0.0001

ILE 138 ILE 139 0.0002

ILE 139 ASP 140 -0.0002

ASP 140 SER 141 0.0002

SER 141 LYS 142 0.0000

LYS 142 GLU 143 -0.0001

GLU 143 ASP 144 0.0001

ASP 144 VAL 145 -0.0005

VAL 145 ASP 146 0.0001

ASP 146 VAL 147 0.0003

VAL 147 LEU 148 0.0003

LEU 148 LEU 149 -0.0002

LEU 149 LEU 150 -0.0001

LEU 150 SER 151 -0.0002

SER 151 TYR 152 -0.0000

TYR 152 GLU 153 -0.0001

GLU 153 LEU 154 0.0000

LEU 154 ASP 155 0.0001

ASP 155 ALA 156 -0.0001

ALA 156 ILE 157 -0.0002

ILE 157 LEU 158 -0.0002

LEU 158 VAL 159 -0.0041

VAL 159 SER 160 -0.0001

SER 160 GLY 161 -0.0001

GLY 161 ASP 162 -0.0000

ASP 162 GLU 163 -0.0000

GLU 163 GLY 164 -0.0005

GLY 164 LEU 165 0.0004

LEU 165 ARG 166 -0.0002

ARG 166 LYS 167 0.0001

LYS 167 TRP 168 -0.0000

TRP 168 ALA 169 -0.0000

ALA 169 ASP 170 0.0060

ASP 170 ARG 171 -0.0002

ARG 171 VAL 172 -0.0002

VAL 172 GLY 173 -0.0001

GLY 173 ILE 174 0.0003

ILE 174 LYS 175 0.0001

LYS 175 LEU 176 0.0004

LEU 176 ILE 177 -0.0003

ILE 177 ASP 178 0.0001

ASP 178 PRO 179 0.0000

PRO 179 LYS 180 -0.0001

LYS 180 ASN 181 0.0064

ASN 181 LEU 182 0.0002

LEU 182 ARG 183 -0.0002

ARG 183 TYR 184 -0.0001

TYR 184 ILE 185 0.0002

ILE 185 MET 186 -0.0002

MET 186 GLU 187 0.0000

GLU 187 ASN 188 -0.0001

ASN 188 LEU 189 0.0000

LEU 189 THR 190 0.0002

THR 190 LYS 191 -0.0005

LYS 191 VAL 192 0.0078

VAL 192 GLY 193 0.0005

GLY 193 ARG 194 -0.0001

ARG 194 MET 1 0.0009

MET 1 ASP 2 0.0002

ASP 2 THR 3 -0.0001

THR 3 PHE 4 -0.0002

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 0.0000

LEU 6 ASP 7 0.0003

ASP 7 THR 8 -0.0001

THR 8 SER 9 0.0002

SER 9 VAL 10 -0.0004

VAL 10 PHE 11 0.0002

PHE 11 THR 12 -0.0007

THR 12 ASN 13 0.0003

ASN 13 PRO 14 0.0003

PRO 14 ASP 15 0.0001

ASP 15 VAL 16 0.0002

VAL 16 TYR 17 0.0001

TYR 17 HIS 18 -0.0000

HIS 18 GLN 19 -0.0000

GLN 19 PHE 20 0.0001

PHE 20 GLU 21 0.0002

GLU 21 GLU 22 0.0001

GLU 22 ASP 23 -0.0009

ASP 23 GLN 24 0.0001

GLN 24 LEU 25 -0.0001

LEU 25 GLY 26 0.0001

GLY 26 ALA 27 -0.0002

ALA 27 ILE 28 -0.0000

ILE 28 GLU 29 0.0004

GLU 29 ASN 30 0.0005

ASN 30 PHE 31 0.0002

PHE 31 ILE 32 -0.0002

ILE 32 SER 33 0.0001

SER 33 LEU 34 0.0066

LEU 34 ALA 35 0.0004

ALA 35 SER 36 0.0001

SER 36 HIS 37 -0.0003

HIS 37 THR 38 -0.0001

THR 38 ASN 39 -0.0001

ASN 39 ALA 40 -0.0004

ALA 40 ASN 41 0.0002

ASN 41 PHE 42 0.0001

PHE 42 PHE 43 0.0002

PHE 43 MET 44 0.0001

MET 44 PRO 45 0.0012

PRO 45 THR 46 -0.0004

THR 46 SER 47 -0.0000

SER 47 VAL 48 -0.0004

VAL 48 TYR 49 0.0003

TYR 49 TYR 50 0.0000

TYR 50 GLU 51 0.0002

GLU 51 PHE 52 0.0002

PHE 52 THR 53 -0.0002

THR 53 LYS 54 -0.0001

LYS 54 MET 55 0.0001

MET 55 VAL 56 -0.0005

VAL 56 SER 57 -0.0001

SER 57 LEU 58 0.0001

LEU 58 GLY 59 0.0003

GLY 59 ASP 60 0.0003

ASP 60 LEU 61 0.0001

LEU 61 ALA 62 -0.0000

ALA 62 PRO 63 -0.0004

PRO 63 LYS 64 0.0002

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 -0.0002

GLU 66 LEU 67 0.0036

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 -0.0005

VAL 69 ARG 70 0.0002

ARG 70 ILE 71 -0.0004

ILE 71 ARG 72 -0.0002

ARG 72 SER 73 -0.0000

SER 73 PRO 74 -0.0001

PRO 74 ARG 75 -0.0000

ARG 75 LYS 76 -0.0001

LYS 76 TRP 77 0.0000

TRP 77 GLY 78 0.0036

GLY 78 LEU 79 0.0003

LEU 79 MET 80 -0.0000

MET 80 VAL 81 -0.0006

VAL 81 PRO 82 0.0001

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 0.0001

GLU 84 PHE 85 0.0003

PHE 85 LEU 86 -0.0001

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 0.0004

PHE 89 ILE 90 0.0000

ILE 90 GLU 91 0.0002

GLU 91 GLU 92 0.0003

GLU 92 VAL 93 0.0000

VAL 93 ARG 94 -0.0002

ARG 94 TYR 95 0.0001

TYR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0001

ILE 97 ASN 98 -0.0000

ASN 98 LYS 99 -0.0003

LYS 99 GLY 100 -0.0002

GLY 100 LEU 101 0.0001

LEU 101 ARG 102 -0.0002

ARG 102 ILE 103 0.0001

ILE 103 ALA 104 -0.0003

ALA 104 GLU 105 0.0002

GLU 105 GLU 106 0.0002

GLU 106 HIS 107 0.0000

HIS 107 ARG 125 -0.0000

ARG 125 LEU 126 0.0002

LEU 126 ARG 127 -0.0001

ARG 127 GLU 128 0.0001

GLU 128 LYS 129 -0.0003

LYS 129 TYR 130 0.0002

TYR 130 ARG 131 -0.0004

ARG 131 GLU 132 -0.0005

GLU 132 ALA 133 0.0003

ALA 133 LEU 134 0.0003

LEU 134 ARG 135 -0.0005

ARG 135 ALA 136 -0.0014

ALA 136 GLY 137 0.0003

GLY 137 ILE 138 -0.0003

ILE 138 ILE 139 -0.0002

ILE 139 ASP 140 0.0001

ASP 140 SER 141 0.0001

SER 141 LYS 142 -0.0001

LYS 142 GLU 143 0.0002

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 0.0002

VAL 145 ASP 146 -0.0000

ASP 146 VAL 147 0.0018

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 0.0000

LEU 149 LEU 150 0.0003

LEU 150 SER 151 0.0000

SER 151 TYR 152 -0.0002

TYR 152 GLU 153 0.0004

GLU 153 LEU 154 -0.0003

LEU 154 ASP 155 -0.0002

ASP 155 ALA 156 -0.0002

ALA 156 ILE 157 0.0004

ILE 157 LEU 158 -0.0014

LEU 158 VAL 159 -0.0001

VAL 159 SER 160 -0.0002

SER 160 GLY 161 0.0004

GLY 161 ASP 162 -0.0003

ASP 162 GLU 163 0.0001

GLU 163 GLY 164 -0.0000

GLY 164 LEU 165 -0.0003

LEU 165 ARG 166 0.0001

ARG 166 LYS 167 0.0003

LYS 167 TRP 168 -0.0002

TRP 168 ALA 169 -0.0005

ALA 169 ASP 170 -0.0000

ASP 170 ARG 171 -0.0005

ARG 171 VAL 172 0.0001

VAL 172 GLY 173 0.0004

GLY 173 ILE 174 -0.0000

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 -0.0001

LEU 176 ILE 177 -0.0000

ILE 177 ASP 178 0.0001

ASP 178 PRO 179 -0.0000

PRO 179 LYS 180 -0.0011

LYS 180 ASN 181 -0.0000

ASN 181 LEU 182 0.0002

LEU 182 ARG 183 -0.0002

ARG 183 TYR 184 0.0000

TYR 184 ILE 185 0.0002

ILE 185 MET 186 -0.0001

MET 186 GLU 187 -0.0002

GLU 187 ASN 188 0.0000

ASN 188 LEU 189 -0.0002

LEU 189 THR 190 -0.0001

THR 190 MET 1 -0.0004

MET 1 ASP 2 -0.0002

ASP 2 THR 3 0.0001

THR 3 PHE 4 0.0002

PHE 4 VAL 5 -0.0002

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0003

SER 9 VAL 10 -0.0005

VAL 10 PHE 11 -0.0003

PHE 11 THR 12 -0.0008

THR 12 ASN 13 0.0004

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 0.0002

ASP 15 VAL 16 0.0003

VAL 16 TYR 17 0.0002

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0004

GLN 19 PHE 20 0.0001

PHE 20 GLU 21 -0.0003

GLU 21 GLU 22 0.0001

GLU 22 ASP 23 0.0042

ASP 23 GLN 24 0.0001

GLN 24 LEU 25 -0.0001

LEU 25 GLY 26 -0.0000

GLY 26 ALA 27 0.0000

ALA 27 ILE 28 -0.0000

ILE 28 GLU 29 -0.0001

GLU 29 ASN 30 -0.0001

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 -0.0005

ILE 32 SER 33 -0.0002

SER 33 LEU 34 -0.0061

LEU 34 ALA 35 0.0000

ALA 35 SER 36 -0.0000

SER 36 HIS 37 0.0004

HIS 37 THR 38 -0.0000

THR 38 ASN 39 -0.0000

ASN 39 ALA 40 0.0002

ALA 40 ASN 41 -0.0003

ASN 41 PHE 42 0.0004

PHE 42 PHE 43 -0.0004

PHE 43 MET 44 0.0000

MET 44 PRO 45 -0.0004

PRO 45 THR 46 -0.0001

THR 46 SER 47 -0.0001

SER 47 VAL 48 0.0002

VAL 48 TYR 49 0.0001

TYR 49 TYR 50 0.0005

TYR 50 GLU 51 -0.0002

GLU 51 PHE 52 -0.0002

PHE 52 THR 53 -0.0003

THR 53 LYS 54 -0.0001

LYS 54 MET 55 -0.0002

MET 55 VAL 56 0.0018

VAL 56 SER 57 0.0001

SER 57 LEU 58 -0.0001

LEU 58 GLY 59 -0.0002

GLY 59 ASP 60 0.0000

ASP 60 LEU 61 0.0001

LEU 61 ALA 62 -0.0000

ALA 62 PRO 63 0.0002

PRO 63 LYS 64 0.0001

LYS 64 PHE 65 0.0001

PHE 65 GLU 66 -0.0000

GLU 66 LEU 67 -0.0000

LEU 67 VAL 68 -0.0001

VAL 68 VAL 69 -0.0000

VAL 69 ARG 70 -0.0000

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 -0.0005

ARG 72 SER 73 0.0003

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 -0.0001

ARG 75 LYS 76 -0.0003

LYS 76 TRP 77 0.0005

TRP 77 GLY 78 -0.0043

GLY 78 LEU 79 -0.0002

LEU 79 MET 80 0.0002

MET 80 VAL 81 0.0002

VAL 81 PRO 82 -0.0002

PRO 82 ALA 83 -0.0003

ALA 83 GLU 84 0.0003

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 0.0001

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 0.0000

GLU 88 PHE 89 0.0017

PHE 89 ILE 90 0.0003

ILE 90 GLU 91 -0.0004

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 0.0001

ARG 94 TYR 95 0.0002

TYR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0004

ILE 97 ASN 98 0.0000

ASN 98 LYS 99 0.0002

LYS 99 GLY 100 0.0003

GLY 100 LEU 101 -0.0001

LEU 101 ARG 102 -0.0001

ARG 102 ILE 103 0.0001

ILE 103 ALA 104 0.0002

ALA 104 GLU 105 0.0004

GLU 105 GLU 106 -0.0002

GLU 106 HIS 107 0.0000

HIS 107 THR 108 0.0001

THR 108 LEU 126 0.0003

LEU 126 ARG 127 -0.0001

ARG 127 GLU 128 0.0000

GLU 128 LYS 129 -0.0001

LYS 129 TYR 130 -0.0001

TYR 130 ARG 131 -0.0003

ARG 131 GLU 132 -0.0001

GLU 132 ALA 133 -0.0004

ALA 133 LEU 134 -0.0003

LEU 134 ARG 135 -0.0001

ARG 135 ALA 136 0.0001

ALA 136 GLY 137 -0.0017

GLY 137 ILE 138 -0.0003

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0000

ASP 140 SER 141 -0.0001

SER 141 LYS 142 -0.0001

LYS 142 GLU 143 0.0002

GLU 143 ASP 144 0.0001

ASP 144 VAL 145 -0.0000

VAL 145 ASP 146 0.0001

ASP 146 VAL 147 -0.0003

VAL 147 LEU 148 0.0011

LEU 148 LEU 149 -0.0001

LEU 149 LEU 150 0.0000

LEU 150 SER 151 0.0003

SER 151 TYR 152 -0.0002

TYR 152 GLU 153 0.0001

GLU 153 LEU 154 -0.0003

LEU 154 ASP 155 0.0004

ASP 155 ALA 156 -0.0003

ALA 156 ILE 157 -0.0002

ILE 157 LEU 158 0.0000

LEU 158 VAL 159 0.0018

VAL 159 SER 160 -0.0002

SER 160 GLY 161 -0.0001

GLY 161 ASP 162 -0.0002

ASP 162 GLU 163 0.0004

GLU 163 GLY 164 0.0000

GLY 164 LEU 165 0.0001

LEU 165 ARG 166 0.0000

ARG 166 LYS 167 0.0004

LYS 167 TRP 168 -0.0000

TRP 168 ALA 169 0.0000

ALA 169 ASP 170 0.0023

ASP 170 ARG 171 -0.0000

ARG 171 VAL 172 0.0004

VAL 172 GLY 173 0.0002

GLY 173 ILE 174 0.0000

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 -0.0000

LEU 176 ILE 177 0.0001

ILE 177 ASP 178 -0.0002

ASP 178 PRO 179 0.0002

PRO 179 LYS 180 -0.0000

LYS 180 ASN 181 -0.0037

ASN 181 LEU 182 -0.0001

LEU 182 ARG 183 -0.0004

ARG 183 TYR 184 0.0004

TYR 184 ILE 185 -0.0004

ILE 185 MET 186 0.0001

MET 186 GLU 187 0.0000

GLU 187 ASN 188 -0.0002

ASN 188 LEU 189 0.0001

LEU 189 THR 190 -0.0001

THR 190 LYS 191 0.0000

LYS 191 VAL 192 -0.0080

VAL 192 GLY 193 0.0000

GLY 193 ARG 194 0.0000

ARG 194 MET 1 0.0023

MET 1 ASP 2 0.0004

ASP 2 THR 3 -0.0001

THR 3 PHE 4 -0.0000

PHE 4 VAL 5 -0.0002

VAL 5 LEU 6 0.0002

LEU 6 ASP 7 -0.0002

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0002

SER 9 VAL 10 0.0001

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 0.0001

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 -0.0002

PRO 14 ASP 15 0.0002

ASP 15 VAL 16 -0.0000

VAL 16 TYR 17 -0.0003

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0001

GLN 19 PHE 20 0.0000

PHE 20 GLU 21 0.0000

GLU 21 GLU 22 -0.0004

GLU 22 ASP 23 -0.0020

ASP 23 GLN 24 0.0002

GLN 24 LEU 25 -0.0002

LEU 25 GLY 26 -0.0002

GLY 26 ALA 27 -0.0000

ALA 27 ILE 28 0.0002

ILE 28 GLU 29 0.0001

GLU 29 ASN 30 -0.0003

ASN 30 PHE 31 0.0000

PHE 31 ILE 32 -0.0004

ILE 32 SER 33 0.0002

SER 33 LEU 34 -0.0009

LEU 34 ALA 35 0.0002

ALA 35 SER 36 0.0000

SER 36 HIS 37 0.0001

HIS 37 THR 38 -0.0001

THR 38 ASN 39 -0.0001

ASN 39 ALA 40 0.0000

ALA 40 ASN 41 0.0000

ASN 41 PHE 42 0.0001

PHE 42 PHE 43 0.0000

PHE 43 MET 44 0.0000

MET 44 PRO 45 -0.0004

PRO 45 THR 46 0.0002

THR 46 SER 47 0.0002

SER 47 VAL 48 0.0001

VAL 48 TYR 49 0.0002

TYR 49 TYR 50 0.0000

TYR 50 GLU 51 -0.0001

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 0.0000

THR 53 LYS 54 0.0000

LYS 54 MET 55 -0.0000

MET 55 VAL 56 0.0010

VAL 56 SER 57 0.0002

SER 57 LEU 58 0.0001

LEU 58 GLY 59 0.0003

GLY 59 ASP 60 0.0002

ASP 60 LEU 61 0.0002

LEU 61 ALA 62 0.0001

ALA 62 PRO 63 0.0002

PRO 63 LYS 64 0.0004

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 0.0003

GLU 66 LEU 67 -0.0004

LEU 67 VAL 68 -0.0002

VAL 68 VAL 69 0.0004

VAL 69 ARG 70 0.0001

ARG 70 ILE 71 0.0000

ILE 71 ARG 72 0.0001

ARG 72 SER 73 -0.0002

SER 73 PRO 74 0.0000

PRO 74 ARG 75 -0.0003

ARG 75 LYS 76 0.0003

LYS 76 TRP 77 0.0005

TRP 77 GLY 78 -0.0054

GLY 78 LEU 79 0.0001

LEU 79 MET 80 0.0001

MET 80 VAL 81 -0.0005

VAL 81 PRO 82 0.0000

PRO 82 ALA 83 0.0002

ALA 83 GLU 84 -0.0001

GLU 84 PHE 85 0.0001

PHE 85 LEU 86 0.0001

LEU 86 TYR 87 -0.0001

TYR 87 GLU 88 -0.0004

GLU 88 PHE 89 0.0020

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 -0.0002

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0002

VAL 93 ARG 94 -0.0000

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 0.0000

ARG 96 ILE 97 0.0003

ILE 97 ASN 98 0.0002

ASN 98 LYS 99 -0.0000

LYS 99 GLY 100 -0.0013

GLY 100 LEU 101 -0.0002

LEU 101 ARG 102 -0.0001

ARG 102 ILE 103 -0.0000

ILE 103 ALA 104 -0.0002

ALA 104 GLU 105 -0.0001

GLU 105 GLU 106 0.0001

GLU 106 HIS 107 -0.0004

HIS 107 ARG 125 -0.0001

ARG 125 LEU 126 -0.0005

LEU 126 ARG 127 0.0003

ARG 127 GLU 128 0.0000

GLU 128 LYS 129 0.0002

LYS 129 TYR 130 -0.0003

TYR 130 ARG 131 0.0001

ARG 131 GLU 132 -0.0004

GLU 132 ALA 133 0.0002

ALA 133 LEU 134 -0.0003

LEU 134 ARG 135 0.0003

ARG 135 ALA 136 -0.0007

ALA 136 GLY 137 -0.0001

GLY 137 ILE 138 0.0004

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0001

ASP 140 SER 141 -0.0002

SER 141 LYS 142 -0.0002

LYS 142 GLU 143 0.0003

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 -0.0005

VAL 145 ASP 146 -0.0002

ASP 146 VAL 147 0.0013

VAL 147 LEU 148 0.0002

LEU 148 LEU 149 -0.0002

LEU 149 LEU 150 0.0001

LEU 150 SER 151 0.0002

SER 151 TYR 152 0.0003

TYR 152 GLU 153 0.0002

GLU 153 LEU 154 -0.0002

LEU 154 ASP 155 0.0002

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 0.0001

ILE 157 LEU 158 -0.0005

LEU 158 VAL 159 0.0003

VAL 159 SER 160 -0.0001

SER 160 GLY 161 -0.0000

GLY 161 ASP 162 0.0001

ASP 162 GLU 163 -0.0000

GLU 163 GLY 164 -0.0001

GLY 164 LEU 165 -0.0004

LEU 165 ARG 166 -0.0005

ARG 166 LYS 167 0.0002

LYS 167 TRP 168 -0.0000

TRP 168 ALA 169 -0.0038

ALA 169 ASP 170 0.0002

ASP 170 ARG 171 0.0002

ARG 171 VAL 172 -0.0001

VAL 172 GLY 173 -0.0001

GLY 173 ILE 174 -0.0001

ILE 174 LYS 175 -0.0001

LYS 175 LEU 176 -0.0001

LEU 176 ILE 177 -0.0001

ILE 177 ASP 178 -0.0000

ASP 178 PRO 179 0.0002

PRO 179 LYS 180 0.0010

LYS 180 ASN 181 -0.0003

ASN 181 LEU 182 0.0002

LEU 182 ARG 183 0.0001

ARG 183 TYR 184 0.0001

TYR 184 ILE 185 -0.0003

ILE 185 MET 186 0.0001

MET 186 GLU 187 0.0000

GLU 187 ASN 188 0.0003

ASN 188 LEU 189 -0.0003

LEU 189 THR 190 -0.0000

THR 190 MET 1 -0.0157

MET 1 ASP 2 0.0001

ASP 2 THR 3 -0.0000

THR 3 PHE 4 0.0003

PHE 4 VAL 5 -0.0002

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0002

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 -0.0002

PHE 11 THR 12 -0.0056

THR 12 ASN 13 -0.0001

ASN 13 PRO 14 -0.0000

PRO 14 ASP 15 0.0002

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0000

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0002

GLN 19 PHE 20 -0.0000

PHE 20 GLU 21 0.0003

GLU 21 GLU 22 -0.0002

GLU 22 ASP 23 0.0033

ASP 23 GLN 24 -0.0002

GLN 24 LEU 25 0.0004

LEU 25 GLY 26 0.0001

GLY 26 ALA 27 0.0001

ALA 27 ILE 28 0.0001

ILE 28 GLU 29 -0.0004

GLU 29 ASN 30 0.0002

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 -0.0005

ILE 32 SER 33 -0.0001

SER 33 LEU 34 -0.0061

LEU 34 ALA 35 0.0000

ALA 35 SER 36 0.0004

SER 36 HIS 37 -0.0002

HIS 37 THR 38 -0.0001

THR 38 ASN 39 0.0000

ASN 39 ALA 40 -0.0000

ALA 40 ASN 41 -0.0000

ASN 41 PHE 42 0.0001

PHE 42 PHE 43 -0.0002

PHE 43 MET 44 0.0001

MET 44 PRO 45 0.0027

PRO 45 THR 46 -0.0003

THR 46 SER 47 0.0001

SER 47 VAL 48 0.0001

VAL 48 TYR 49 -0.0001

TYR 49 TYR 50 0.0000

TYR 50 GLU 51 -0.0001

GLU 51 PHE 52 -0.0000

PHE 52 THR 53 0.0000

THR 53 LYS 54 -0.0000

LYS 54 MET 55 0.0001

MET 55 VAL 56 0.0008

VAL 56 SER 57 0.0001

SER 57 LEU 58 0.0003

LEU 58 GLY 59 -0.0002

GLY 59 ASP 60 -0.0000

ASP 60 LEU 61 -0.0005

LEU 61 ALA 62 -0.0001

ALA 62 PRO 63 0.0002

PRO 63 LYS 64 -0.0001

LYS 64 PHE 65 -0.0000

PHE 65 GLU 66 -0.0003

GLU 66 LEU 67 -0.0061

LEU 67 VAL 68 0.0000

VAL 68 VAL 69 -0.0003

VAL 69 ARG 70 -0.0002

ARG 70 ILE 71 0.0003

ILE 71 ARG 72 -0.0001

ARG 72 SER 73 -0.0001

SER 73 PRO 74 -0.0002

PRO 74 ARG 75 -0.0002

ARG 75 LYS 76 0.0002

LYS 76 TRP 77 -0.0003

TRP 77 GLY 78 0.0232

GLY 78 LEU 79 0.0002

LEU 79 MET 80 0.0003

MET 80 VAL 81 -0.0001

VAL 81 PRO 82 -0.0004

PRO 82 ALA 83 -0.0000

ALA 83 GLU 84 0.0001

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 -0.0004

LEU 86 TYR 87 -0.0000

TYR 87 GLU 88 -0.0002

GLU 88 PHE 89 -0.0010

PHE 89 ILE 90 0.0004

ILE 90 GLU 91 -0.0001

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 -0.0002

TYR 95 ARG 96 0.0001

ARG 96 ILE 97 -0.0001

ILE 97 ASN 98 0.0003

ASN 98 LYS 99 -0.0001

LYS 99 GLY 100 0.0056

GLY 100 LEU 101 0.0002

LEU 101 ARG 102 0.0001

ARG 102 ILE 103 0.0000

ILE 103 ALA 104 0.0002

ALA 104 GLU 105 0.0003

GLU 105 GLU 106 -0.0002

GLU 106 HIS 107 0.0000

HIS 107 THR 108 -0.0002

THR 108 LEU 126 -0.0018

LEU 126 ARG 127 -0.0000

ARG 127 GLU 128 0.0005

GLU 128 LYS 129 0.0005

LYS 129 TYR 130 -0.0001

TYR 130 ARG 131 -0.0001

ARG 131 GLU 132 -0.0001

GLU 132 ALA 133 -0.0002

ALA 133 LEU 134 0.0004

LEU 134 ARG 135 -0.0002

ARG 135 ALA 136 0.0003

ALA 136 GLY 137 0.0100

GLY 137 ILE 138 -0.0001

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0002

ASP 140 SER 141 0.0000

SER 141 LYS 142 0.0004

LYS 142 GLU 143 -0.0000

GLU 143 ASP 144 0.0002

ASP 144 VAL 145 -0.0002

VAL 145 ASP 146 0.0002

ASP 146 VAL 147 0.0002

VAL 147 LEU 148 -0.0007

LEU 148 LEU 149 -0.0001

LEU 149 LEU 150 -0.0002

LEU 150 SER 151 -0.0002

SER 151 TYR 152 -0.0002

TYR 152 GLU 153 -0.0000

GLU 153 LEU 154 0.0003

LEU 154 ASP 155 0.0000

ASP 155 ALA 156 -0.0001

ALA 156 ILE 157 -0.0004

ILE 157 LEU 158 0.0001

LEU 158 VAL 159 -0.0052

VAL 159 SER 160 -0.0002

SER 160 GLY 161 -0.0000

GLY 161 ASP 162 -0.0002

ASP 162 GLU 163 -0.0000

GLU 163 GLY 164 0.0001

GLY 164 LEU 165 -0.0000

LEU 165 ARG 166 -0.0003

ARG 166 LYS 167 -0.0001

LYS 167 TRP 168 -0.0004

TRP 168 ALA 169 -0.0001

ALA 169 ASP 170 0.0099

ASP 170 ARG 171 0.0001

ARG 171 VAL 172 -0.0002

VAL 172 GLY 173 -0.0000

GLY 173 ILE 174 0.0000

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 -0.0000

LEU 176 ILE 177 -0.0000

ILE 177 ASP 178 0.0002

ASP 178 PRO 179 -0.0002

PRO 179 LYS 180 0.0001

LYS 180 ASN 181 0.0141

ASN 181 LEU 182 0.0002

LEU 182 ARG 183 -0.0002

ARG 183 TYR 184 0.0003

TYR 184 ILE 185 -0.0003

ILE 185 MET 186 -0.0003

MET 186 GLU 187 0.0001

GLU 187 ASN 188 0.0000

ASN 188 LEU 189 0.0005

LEU 189 THR 190 -0.0004

THR 190 LYS 191 -0.0003

LYS 191 VAL 192 -0.0197

VAL 192 GLY 193 0.0003

GLY 193 ARG 194 -0.0000

ARG 194 MET 1 -0.0009

MET 1 ASP 2 -0.0003

ASP 2 THR 3 -0.0001

THR 3 PHE 4 -0.0002

PHE 4 VAL 5 0.0003

VAL 5 LEU 6 -0.0001

LEU 6 ASP 7 0.0000

ASP 7 THR 8 -0.0002

THR 8 SER 9 0.0001

SER 9 VAL 10 0.0003

VAL 10 PHE 11 -0.0004

PHE 11 THR 12 0.0010

THR 12 ASN 13 -0.0002

ASN 13 PRO 14 0.0003

PRO 14 ASP 15 0.0000

ASP 15 VAL 16 -0.0001

VAL 16 TYR 17 -0.0003

TYR 17 HIS 18 -0.0002

HIS 18 GLN 19 -0.0003

GLN 19 PHE 20 0.0001

PHE 20 GLU 21 0.0002

GLU 21 GLU 22 -0.0003

GLU 22 ASP 23 0.0008

ASP 23 GLN 24 0.0002

GLN 24 LEU 25 -0.0001

LEU 25 GLY 26 0.0001

GLY 26 ALA 27 -0.0004

ALA 27 ILE 28 0.0001

ILE 28 GLU 29 -0.0004

GLU 29 ASN 30 -0.0000

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 -0.0004

ILE 32 SER 33 -0.0001

SER 33 LEU 34 -0.0006

LEU 34 ALA 35 -0.0000

ALA 35 SER 36 0.0002

SER 36 HIS 37 0.0003

HIS 37 THR 38 0.0001

THR 38 ASN 39 0.0002

ASN 39 ALA 40 0.0001

ALA 40 ASN 41 0.0002

ASN 41 PHE 42 -0.0003

PHE 42 PHE 43 0.0000

PHE 43 MET 44 -0.0001

MET 44 PRO 45 -0.0025

PRO 45 THR 46 0.0002

THR 46 SER 47 -0.0001

SER 47 VAL 48 -0.0001

VAL 48 TYR 49 -0.0002

TYR 49 TYR 50 -0.0001

TYR 50 GLU 51 0.0001

GLU 51 PHE 52 -0.0002

PHE 52 THR 53 0.0003

THR 53 LYS 54 0.0001

LYS 54 MET 55 0.0001

MET 55 VAL 56 -0.0047

VAL 56 SER 57 0.0000

SER 57 LEU 58 0.0000

LEU 58 GLY 59 0.0001

GLY 59 ASP 60 -0.0006

ASP 60 LEU 61 -0.0001

LEU 61 ALA 62 -0.0001

ALA 62 PRO 63 -0.0003

PRO 63 LYS 64 -0.0000

LYS 64 PHE 65 0.0002

PHE 65 GLU 66 -0.0002

GLU 66 LEU 67 0.0046

LEU 67 VAL 68 0.0004

VAL 68 VAL 69 0.0000

VAL 69 ARG 70 -0.0001

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 0.0004

ARG 72 SER 73 0.0001

SER 73 PRO 74 -0.0004

PRO 74 ARG 75 -0.0001

ARG 75 LYS 76 -0.0005

LYS 76 TRP 77 -0.0001

TRP 77 GLY 78 0.0135

GLY 78 LEU 79 -0.0000

LEU 79 MET 80 -0.0000

MET 80 VAL 81 0.0002

VAL 81 PRO 82 0.0000

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 -0.0003

GLU 84 PHE 85 -0.0002

PHE 85 LEU 86 0.0004

LEU 86 TYR 87 0.0000

TYR 87 GLU 88 0.0005

GLU 88 PHE 89 -0.0100

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 -0.0001

GLU 91 GLU 92 0.0003

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 0.0002

TYR 95 ARG 96 0.0004

ARG 96 ILE 97 -0.0001

ILE 97 ASN 98 0.0000

ASN 98 LYS 99 0.0002

LYS 99 GLY 100 -0.0035

GLY 100 LEU 101 0.0001

LEU 101 ARG 102 -0.0006

ARG 102 ILE 103 0.0000

ILE 103 ALA 104 0.0003

ALA 104 GLU 105 -0.0001

GLU 105 GLU 106 0.0002

GLU 106 HIS 107 -0.0002

HIS 107 ARG 125 -0.0006

ARG 125 LEU 126 -0.0003

LEU 126 ARG 127 -0.0003

ARG 127 GLU 128 0.0000

GLU 128 LYS 129 0.0000

LYS 129 TYR 130 0.0000

TYR 130 ARG 131 -0.0002

ARG 131 GLU 132 -0.0004

GLU 132 ALA 133 -0.0001

ALA 133 LEU 134 0.0006

LEU 134 ARG 135 -0.0001

ARG 135 ALA 136 -0.0081

ALA 136 GLY 137 0.0002

GLY 137 ILE 138 0.0001

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0002

ASP 140 SER 141 0.0002

SER 141 LYS 142 0.0000

LYS 142 GLU 143 0.0005

GLU 143 ASP 144 -0.0000

ASP 144 VAL 145 0.0002

VAL 145 ASP 146 0.0000

ASP 146 VAL 147 -0.0016

VAL 147 LEU 148 -0.0000

LEU 148 LEU 149 -0.0003

LEU 149 LEU 150 -0.0003

LEU 150 SER 151 -0.0001

SER 151 TYR 152 -0.0001

TYR 152 GLU 153 0.0001

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 0.0001

ASP 155 ALA 156 -0.0001

ALA 156 ILE 157 0.0001

ILE 157 LEU 158 0.0029

LEU 158 VAL 159 -0.0004

VAL 159 SER 160 0.0003

SER 160 GLY 161 0.0000

GLY 161 ASP 162 -0.0002

ASP 162 GLU 163 -0.0000

GLU 163 GLY 164 -0.0000

GLY 164 LEU 165 0.0000

LEU 165 ARG 166 -0.0003

ARG 166 LYS 167 0.0004

LYS 167 TRP 168 -0.0001

TRP 168 ALA 169 0.0017

ALA 169 ASP 170 0.0000

ASP 170 ARG 171 0.0001

ARG 171 VAL 172 -0.0000

VAL 172 GLY 173 0.0001

GLY 173 ILE 174 0.0001

ILE 174 LYS 175 -0.0003

LYS 175 LEU 176 0.0000

LEU 176 ILE 177 0.0003

ILE 177 ASP 178 -0.0001

ASP 178 PRO 179 0.0003

PRO 179 LYS 180 -0.0023

LYS 180 ASN 181 0.0001

ASN 181 LEU 182 0.0001

LEU 182 ARG 183 -0.0001

ARG 183 TYR 184 -0.0000

TYR 184 ILE 185 0.0000

ILE 185 MET 186 -0.0003

MET 186 GLU 187 -0.0005

GLU 187 ASN 188 -0.0002

ASN 188 LEU 189 0.0001

LEU 189 THR 190 -0.0004

THR 190 MET 1 -0.1045

MET 1 ASP 2 -0.0003

ASP 2 THR 3 0.0001

THR 3 PHE 4 -0.0001

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 0.0001

LEU 6 ASP 7 -0.0004

ASP 7 THR 8 -0.0001

THR 8 SER 9 -0.0003

SER 9 VAL 10 0.0003

VAL 10 PHE 11 -0.0001

PHE 11 THR 12 0.0017

THR 12 ASN 13 0.0001

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 -0.0001

VAL 16 TYR 17 0.0002

TYR 17 HIS 18 -0.0000

HIS 18 GLN 19 -0.0000

GLN 19 PHE 20 0.0000

PHE 20 GLU 21 0.0000

GLU 21 GLU 22 -0.0001

GLU 22 ASP 23 0.0002

ASP 23 GLN 24 -0.0000

GLN 24 LEU 25 0.0000

LEU 25 GLY 26 0.0004

GLY 26 ALA 27 0.0002

ALA 27 ILE 28 0.0004

ILE 28 GLU 29 -0.0000

GLU 29 ASN 30 -0.0002

ASN 30 PHE 31 -0.0001

PHE 31 ILE 32 -0.0002

ILE 32 SER 33 0.0000

SER 33 LEU 34 -0.0055

LEU 34 ALA 35 -0.0004

ALA 35 SER 36 0.0003

SER 36 HIS 37 -0.0002

HIS 37 THR 38 0.0002

THR 38 ASN 39 -0.0002

ASN 39 ALA 40 -0.0001

ALA 40 ASN 41 0.0003

ASN 41 PHE 42 -0.0002

PHE 42 PHE 43 -0.0000

PHE 43 MET 44 -0.0001

MET 44 PRO 45 0.0003

PRO 45 THR 46 -0.0001

THR 46 SER 47 0.0002

SER 47 VAL 48 -0.0002

VAL 48 TYR 49 -0.0002

TYR 49 TYR 50 -0.0001

TYR 50 GLU 51 -0.0001

GLU 51 PHE 52 0.0004

PHE 52 THR 53 0.0004

THR 53 LYS 54 -0.0003

LYS 54 MET 55 -0.0004

MET 55 VAL 56 0.0030

VAL 56 SER 57 -0.0001

SER 57 LEU 58 0.0000

LEU 58 GLY 59 0.0002

GLY 59 ASP 60 -0.0001

ASP 60 LEU 61 -0.0005

LEU 61 ALA 62 -0.0002

ALA 62 PRO 63 -0.0000

PRO 63 LYS 64 -0.0002

LYS 64 PHE 65 -0.0002

PHE 65 GLU 66 0.0001

GLU 66 LEU 67 -0.0014

LEU 67 VAL 68 0.0001

VAL 68 VAL 69 0.0001

VAL 69 ARG 70 -0.0004

ARG 70 ILE 71 0.0002

ILE 71 ARG 72 -0.0003

ARG 72 SER 73 -0.0002

SER 73 PRO 74 0.0004

PRO 74 ARG 75 0.0002

ARG 75 LYS 76 -0.0000

LYS 76 TRP 77 -0.0004

TRP 77 GLY 78 -0.0033

GLY 78 LEU 79 -0.0001

LEU 79 MET 80 -0.0001

MET 80 VAL 81 -0.0000

VAL 81 PRO 82 0.0004

PRO 82 ALA 83 -0.0002

ALA 83 GLU 84 0.0002

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 -0.0001

LEU 86 TYR 87 0.0002

TYR 87 GLU 88 -0.0001

GLU 88 PHE 89 0.0033

PHE 89 ILE 90 0.0003

ILE 90 GLU 91 0.0001

GLU 91 GLU 92 -0.0000

GLU 92 VAL 93 -0.0004

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 -0.0001

TYR 95 ARG 96 0.0001

ARG 96 ILE 97 0.0002

ILE 97 ASN 98 0.0001

ASN 98 LYS 99 -0.0002

LYS 99 GLY 100 0.0019

GLY 100 LEU 101 0.0002

LEU 101 ARG 102 -0.0003

ARG 102 ILE 103 0.0002

ILE 103 ALA 104 -0.0000

ALA 104 GLU 105 -0.0000

GLU 105 GLU 106 -0.0001

GLU 106 HIS 107 0.0002

HIS 107 THR 108 0.0000

THR 108 LEU 126 0.0005

LEU 126 ARG 127 0.0003

ARG 127 GLU 128 -0.0002

GLU 128 LYS 129 -0.0002

LYS 129 TYR 130 0.0003

TYR 130 ARG 131 -0.0002

ARG 131 GLU 132 0.0001

GLU 132 ALA 133 -0.0001

ALA 133 LEU 134 0.0002

LEU 134 ARG 135 0.0002

ARG 135 ALA 136 0.0001

ALA 136 GLY 137 -0.0015

GLY 137 ILE 138 -0.0001

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0002

ASP 140 SER 141 -0.0002

SER 141 LYS 142 -0.0003

LYS 142 GLU 143 -0.0000

GLU 143 ASP 144 0.0003

ASP 144 VAL 145 0.0002

VAL 145 ASP 146 0.0002

ASP 146 VAL 147 -0.0000

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 0.0000

LEU 149 LEU 150 -0.0001

LEU 150 SER 151 0.0001

SER 151 TYR 152 0.0002

TYR 152 GLU 153 -0.0002

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 -0.0000

ASP 155 ALA 156 -0.0000

ALA 156 ILE 157 -0.0002

ILE 157 LEU 158 0.0000

LEU 158 VAL 159 0.0078

VAL 159 SER 160 0.0000

SER 160 GLY 161 -0.0002

GLY 161 ASP 162 -0.0004

ASP 162 GLU 163 -0.0002

GLU 163 GLY 164 0.0000

GLY 164 LEU 165 0.0003

LEU 165 ARG 166 0.0000

ARG 166 LYS 167 -0.0003

LYS 167 TRP 168 -0.0000

TRP 168 ALA 169 0.0001

ALA 169 ASP 170 -0.0014

ASP 170 ARG 171 -0.0002

ARG 171 VAL 172 0.0003

VAL 172 GLY 173 -0.0002

GLY 173 ILE 174 -0.0002

ILE 174 LYS 175 0.0000

LYS 175 LEU 176 -0.0002

LEU 176 ILE 177 0.0004

ILE 177 ASP 178 -0.0005

ASP 178 PRO 179 -0.0002

PRO 179 LYS 180 -0.0005

LYS 180 ASN 181 -0.0031

ASN 181 LEU 182 0.0003

LEU 182 ARG 183 -0.0004

ARG 183 TYR 184 -0.0000

TYR 184 ILE 185 0.0003

ILE 185 MET 186 0.0000

MET 186 GLU 187 -0.0003

GLU 187 ASN 188 -0.0002

ASN 188 LEU 189 -0.0000

LEU 189 THR 190 -0.0003

THR 190 LYS 191 0.0002

LYS 191 VAL 192 -0.0019

VAL 192 GLY 193 -0.0003

GLY 193 ARG 194 -0.0005

ARG 194 MET 1 0.0018

MET 1 ASP 2 -0.0003

ASP 2 THR 3 0.0001

THR 3 PHE 4 -0.0001

PHE 4 VAL 5 0.0002

VAL 5 LEU 6 -0.0000

LEU 6 ASP 7 -0.0001

ASP 7 THR 8 -0.0001

THR 8 SER 9 0.0004

SER 9 VAL 10 -0.0001

VAL 10 PHE 11 0.0001

PHE 11 THR 12 -0.0047

THR 12 ASN 13 -0.0000

ASN 13 PRO 14 0.0000

PRO 14 ASP 15 -0.0001

ASP 15 VAL 16 0.0003

VAL 16 TYR 17 0.0001

TYR 17 HIS 18 0.0002

HIS 18 GLN 19 -0.0003

GLN 19 PHE 20 -0.0004

PHE 20 GLU 21 0.0003

GLU 21 GLU 22 0.0003

GLU 22 ASP 23 0.0020

ASP 23 GLN 24 -0.0001

GLN 24 LEU 25 -0.0002

LEU 25 GLY 26 -0.0003

GLY 26 ALA 27 -0.0000

ALA 27 ILE 28 0.0000

ILE 28 GLU 29 -0.0001

GLU 29 ASN 30 -0.0000

ASN 30 PHE 31 0.0001

PHE 31 ILE 32 -0.0004

ILE 32 SER 33 0.0002

SER 33 LEU 34 -0.0076

LEU 34 ALA 35 0.0000

ALA 35 SER 36 -0.0001

SER 36 HIS 37 -0.0001

HIS 37 THR 38 -0.0000

THR 38 ASN 39 -0.0005

ASN 39 ALA 40 -0.0000

ALA 40 ASN 41 0.0003

ASN 41 PHE 42 -0.0003

PHE 42 PHE 43 0.0001

PHE 43 MET 44 -0.0003

MET 44 PRO 45 0.0047

PRO 45 THR 46 0.0002

THR 46 SER 47 0.0000

SER 47 VAL 48 -0.0002

VAL 48 TYR 49 0.0003

TYR 49 TYR 50 -0.0000

TYR 50 GLU 51 -0.0002

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 -0.0001

THR 53 LYS 54 0.0002

LYS 54 MET 55 0.0000

MET 55 VAL 56 0.0095

VAL 56 SER 57 0.0003

SER 57 LEU 58 0.0002

LEU 58 GLY 59 0.0004

GLY 59 ASP 60 -0.0004

ASP 60 LEU 61 -0.0004

LEU 61 ALA 62 -0.0001

ALA 62 PRO 63 0.0001

PRO 63 LYS 64 -0.0001

LYS 64 PHE 65 -0.0001

PHE 65 GLU 66 0.0003

GLU 66 LEU 67 -0.0042

LEU 67 VAL 68 0.0003

VAL 68 VAL 69 -0.0001

VAL 69 ARG 70 0.0000

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 0.0003

ARG 72 SER 73 -0.0002

SER 73 PRO 74 0.0001

PRO 74 ARG 75 0.0001

ARG 75 LYS 76 -0.0000

LYS 76 TRP 77 -0.0002

TRP 77 GLY 78 -0.0184

GLY 78 LEU 79 0.0002

LEU 79 MET 80 -0.0002

MET 80 VAL 81 0.0001

VAL 81 PRO 82 0.0004

PRO 82 ALA 83 -0.0002

ALA 83 GLU 84 0.0001

GLU 84 PHE 85 -0.0002

PHE 85 LEU 86 0.0001

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 -0.0002

GLU 88 PHE 89 0.0045

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 -0.0002

GLU 91 GLU 92 0.0001

GLU 92 VAL 93 -0.0000

VAL 93 ARG 94 0.0000

ARG 94 TYR 95 0.0001

TYR 95 ARG 96 -0.0002

ARG 96 ILE 97 0.0000

ILE 97 ASN 98 -0.0000

ASN 98 LYS 99 -0.0004

LYS 99 GLY 100 -0.0031

GLY 100 LEU 101 -0.0000

LEU 101 ARG 102 0.0001

ARG 102 ILE 103 -0.0001

ILE 103 ALA 104 0.0001

ALA 104 GLU 105 0.0001

GLU 105 GLU 106 0.0002

GLU 106 HIS 107 -0.0001

HIS 107 ARG 125 -0.0001

ARG 125 LEU 126 0.0004

LEU 126 ARG 127 0.0001

ARG 127 GLU 128 0.0002

GLU 128 LYS 129 -0.0001

LYS 129 TYR 130 -0.0003

TYR 130 ARG 131 -0.0004

ARG 131 GLU 132 0.0001

GLU 132 ALA 133 0.0002

ALA 133 LEU 134 0.0002

LEU 134 ARG 135 0.0001

ARG 135 ALA 136 0.0023

ALA 136 GLY 137 0.0001

GLY 137 ILE 138 0.0003

ILE 138 ILE 139 0.0003

ILE 139 ASP 140 0.0002

ASP 140 SER 141 -0.0003

SER 141 LYS 142 -0.0003

LYS 142 GLU 143 0.0003

GLU 143 ASP 144 0.0003

ASP 144 VAL 145 -0.0001

VAL 145 ASP 146 -0.0002

ASP 146 VAL 147 0.0038

VAL 147 LEU 148 -0.0001

LEU 148 LEU 149 0.0002

LEU 149 LEU 150 -0.0004

LEU 150 SER 151 -0.0001

SER 151 TYR 152 0.0002

TYR 152 GLU 153 0.0001

GLU 153 LEU 154 0.0003

LEU 154 ASP 155 -0.0001

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 0.0003

ILE 157 LEU 158 -0.0021

LEU 158 VAL 159 0.0000

VAL 159 SER 160 0.0003

SER 160 GLY 161 -0.0001

GLY 161 ASP 162 0.0001

ASP 162 GLU 163 0.0002

GLU 163 GLY 164 0.0001

GLY 164 LEU 165 0.0004

LEU 165 ARG 166 0.0001

ARG 166 LYS 167 0.0002

LYS 167 TRP 168 -0.0000

TRP 168 ALA 169 -0.0034

ALA 169 ASP 170 -0.0001

ASP 170 ARG 171 -0.0000

ARG 171 VAL 172 -0.0003

VAL 172 GLY 173 -0.0002

GLY 173 ILE 174 0.0002

ILE 174 LYS 175 0.0002

LYS 175 LEU 176 -0.0001

LEU 176 ILE 177 0.0002

ILE 177 ASP 178 -0.0002

ASP 178 PRO 179 0.0001

PRO 179 LYS 180 0.0017

LYS 180 ASN 181 0.0003

ASN 181 LEU 182 0.0000

LEU 182 ARG 183 -0.0003

ARG 183 TYR 184 -0.0002

TYR 184 ILE 185 -0.0001

ILE 185 MET 186 -0.0001

MET 186 GLU 187 0.0001

GLU 187 ASN 188 0.0003

ASN 188 LEU 189 0.0004

LEU 189 THR 190 0.0000

THR 190 MET 1 -0.0116

MET 1 ASP 2 0.0000

ASP 2 THR 3 0.0000

THR 3 PHE 4 -0.0001

PHE 4 VAL 5 0.0001

VAL 5 LEU 6 -0.0000

LEU 6 ASP 7 0.0000

ASP 7 THR 8 0.0000

THR 8 SER 9 0.0003

SER 9 VAL 10 0.0003

VAL 10 PHE 11 0.0001

PHE 11 THR 12 -0.0054

THR 12 ASN 13 0.0003

ASN 13 PRO 14 0.0001

PRO 14 ASP 15 -0.0002

ASP 15 VAL 16 0.0001

VAL 16 TYR 17 0.0001

TYR 17 HIS 18 0.0001

HIS 18 GLN 19 -0.0000

GLN 19 PHE 20 -0.0001

PHE 20 GLU 21 -0.0001

GLU 21 GLU 22 0.0004

GLU 22 ASP 23 -0.0004

ASP 23 GLN 24 -0.0003

GLN 24 LEU 25 0.0003

LEU 25 GLY 26 -0.0001

GLY 26 ALA 27 0.0001

ALA 27 ILE 28 0.0000

ILE 28 GLU 29 -0.0003

GLU 29 ASN 30 -0.0001

ASN 30 PHE 31 0.0002

PHE 31 ILE 32 -0.0002

ILE 32 SER 33 0.0003

SER 33 LEU 34 0.0073

LEU 34 ALA 35 0.0000

ALA 35 SER 36 0.0002

SER 36 HIS 37 -0.0003

HIS 37 THR 38 0.0001

THR 38 ASN 39 -0.0000

ASN 39 ALA 40 -0.0005

ALA 40 ASN 41 0.0004

ASN 41 PHE 42 -0.0003

PHE 42 PHE 43 0.0000

PHE 43 MET 44 -0.0000

MET 44 PRO 45 0.0087

PRO 45 THR 46 -0.0001

THR 46 SER 47 0.0003

SER 47 VAL 48 0.0001

VAL 48 TYR 49 0.0001

TYR 49 TYR 50 0.0002

TYR 50 GLU 51 0.0003

GLU 51 PHE 52 -0.0001

PHE 52 THR 53 -0.0003

THR 53 LYS 54 -0.0001

LYS 54 MET 55 0.0003

MET 55 VAL 56 0.0030

VAL 56 SER 57 -0.0003

SER 57 LEU 58 -0.0000

LEU 58 GLY 59 -0.0003

GLY 59 ASP 60 0.0005

ASP 60 LEU 61 -0.0000

LEU 61 ALA 62 0.0001

ALA 62 PRO 63 0.0001

PRO 63 LYS 64 0.0001

LYS 64 PHE 65 0.0001

PHE 65 GLU 66 0.0001

GLU 66 LEU 67 -0.0022

LEU 67 VAL 68 0.0003

VAL 68 VAL 69 -0.0002

VAL 69 ARG 70 -0.0001

ARG 70 ILE 71 0.0001

ILE 71 ARG 72 0.0001

ARG 72 SER 73 0.0000

SER 73 PRO 74 -0.0003

PRO 74 ARG 75 -0.0000

ARG 75 LYS 76 0.0004

LYS 76 TRP 77 -0.0000

TRP 77 GLY 78 0.0007

GLY 78 LEU 79 0.0001

LEU 79 MET 80 -0.0000

MET 80 VAL 81 0.0001

VAL 81 PRO 82 0.0000

PRO 82 ALA 83 -0.0000

ALA 83 GLU 84 0.0000

GLU 84 PHE 85 0.0002

PHE 85 LEU 86 -0.0001

LEU 86 TYR 87 -0.0002

TYR 87 GLU 88 0.0002

GLU 88 PHE 89 0.0010

PHE 89 ILE 90 -0.0004

ILE 90 GLU 91 0.0003

GLU 91 GLU 92 -0.0001

GLU 92 VAL 93 0.0003

VAL 93 ARG 94 -0.0001

ARG 94 TYR 95 0.0002

TYR 95 ARG 96 -0.0001

ARG 96 ILE 97 0.0001

ILE 97 ASN 98 -0.0004

ASN 98 LYS 99 -0.0002

LYS 99 GLY 100 -0.0039

GLY 100 LEU 101 -0.0004

LEU 101 ARG 102 0.0001

ARG 102 ILE 103 -0.0002

ILE 103 ALA 104 0.0001

ALA 104 GLU 105 0.0001

GLU 105 GLU 106 -0.0003

GLU 106 HIS 107 -0.0003

HIS 107 THR 108 0.0001

THR 108 LEU 126 0.0019

LEU 126 ARG 127 -0.0001

ARG 127 GLU 128 -0.0005

GLU 128 LYS 129 -0.0003

LYS 129 TYR 130 0.0001

TYR 130 ARG 131 -0.0002

ARG 131 GLU 132 0.0002

GLU 132 ALA 133 -0.0003

ALA 133 LEU 134 -0.0001

LEU 134 ARG 135 -0.0002

ARG 135 ALA 136 0.0001

ALA 136 GLY 137 -0.0079

GLY 137 ILE 138 0.0000

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0000

ASP 140 SER 141 -0.0001

SER 141 LYS 142 -0.0005

LYS 142 GLU 143 0.0000

GLU 143 ASP 144 -0.0001

ASP 144 VAL 145 -0.0000

VAL 145 ASP 146 0.0002

ASP 146 VAL 147 0.0000

VAL 147 LEU 148 0.0049

LEU 148 LEU 149 0.0004

LEU 149 LEU 150 -0.0001

LEU 150 SER 151 -0.0001

SER 151 TYR 152 0.0002

TYR 152 GLU 153 0.0001

GLU 153 LEU 154 0.0001

LEU 154 ASP 155 0.0003

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 0.0002

ILE 157 LEU 158 0.0000

LEU 158 VAL 159 0.0081

VAL 159 SER 160 0.0001

SER 160 GLY 161 0.0001

GLY 161 ASP 162 0.0000

ASP 162 GLU 163 -0.0002

GLU 163 GLY 164 -0.0004

GLY 164 LEU 165 0.0001

LEU 165 ARG 166 -0.0003

ARG 166 LYS 167 -0.0006

LYS 167 TRP 168 0.0000

TRP 168 ALA 169 0.0001

ALA 169 ASP 170 -0.0199

ASP 170 ARG 171 0.0002

ARG 171 VAL 172 0.0002

VAL 172 GLY 173 0.0004

GLY 173 ILE 174 0.0001

ILE 174 LYS 175 -0.0002

LYS 175 LEU 176 -0.0001

LEU 176 ILE 177 -0.0002

ILE 177 ASP 178 0.0001

ASP 178 PRO 179 0.0004

PRO 179 LYS 180 0.0003

LYS 180 ASN 181 0.0018

ASN 181 LEU 182 -0.0001

LEU 182 ARG 183 0.0001

ARG 183 TYR 184 -0.0001

TYR 184 ILE 185 0.0001

ILE 185 MET 186 0.0000

MET 186 GLU 187 0.0000

GLU 187 ASN 188 0.0000

ASN 188 LEU 189 -0.0000

LEU 189 THR 190 -0.0002

THR 190 LYS 191 0.0001

LYS 191 VAL 192 0.0004

VAL 192 GLY 193 -0.0002

GLY 193 ARG 194 -0.0003

ARG 194 MET 1 0.0015

MET 1 ASP 2 0.0001

ASP 2 THR 3 -0.0002

THR 3 PHE 4 -0.0004

PHE 4 VAL 5 0.0004

VAL 5 LEU 6 0.0004

LEU 6 ASP 7 -0.0003

ASP 7 THR 8 0.0001

THR 8 SER 9 -0.0002

SER 9 VAL 10 -0.0002

VAL 10 PHE 11 0.0003

PHE 11 THR 12 -0.0031

THR 12 ASN 13 -0.0002

ASN 13 PRO 14 -0.0002

PRO 14 ASP 15 -0.0000

ASP 15 VAL 16 0.0000

VAL 16 TYR 17 -0.0000

TYR 17 HIS 18 -0.0001

HIS 18 GLN 19 0.0001

GLN 19 PHE 20 0.0003

PHE 20 GLU 21 0.0001

GLU 21 GLU 22 -0.0001

GLU 22 ASP 23 0.0005

ASP 23 GLN 24 0.0002

GLN 24 LEU 25 0.0000

LEU 25 GLY 26 0.0002

GLY 26 ALA 27 0.0000

ALA 27 ILE 28 -0.0002

ILE 28 GLU 29 0.0002

GLU 29 ASN 30 0.0001

ASN 30 PHE 31 -0.0002

PHE 31 ILE 32 -0.0002

ILE 32 SER 33 -0.0003

SER 33 LEU 34 0.0044

LEU 34 ALA 35 -0.0002

ALA 35 SER 36 -0.0002

SER 36 HIS 37 -0.0003

HIS 37 THR 38 -0.0001

THR 38 ASN 39 0.0001

ASN 39 ALA 40 -0.0000

ALA 40 ASN 41 0.0004

ASN 41 PHE 42 -0.0004

PHE 42 PHE 43 0.0002

PHE 43 MET 44 -0.0003

MET 44 PRO 45 0.0021

PRO 45 THR 46 0.0000

THR 46 SER 47 -0.0001

SER 47 VAL 48 0.0004

VAL 48 TYR 49 0.0000

TYR 49 TYR 50 0.0001

TYR 50 GLU 51 0.0000

GLU 51 PHE 52 -0.0003

PHE 52 THR 53 0.0005

THR 53 LYS 54 0.0002

LYS 54 MET 55 -0.0002

MET 55 VAL 56 0.0008

VAL 56 SER 57 0.0004

SER 57 LEU 58 0.0001

LEU 58 GLY 59 0.0002

GLY 59 ASP 60 0.0004

ASP 60 LEU 61 -0.0002

LEU 61 ALA 62 -0.0002

ALA 62 PRO 63 -0.0002

PRO 63 LYS 64 0.0000

LYS 64 PHE 65 -0.0000

PHE 65 GLU 66 -0.0001

GLU 66 LEU 67 0.0011

LEU 67 VAL 68 -0.0002

VAL 68 VAL 69 0.0000

VAL 69 ARG 70 -0.0002

ARG 70 ILE 71 -0.0001

ILE 71 ARG 72 -0.0004

ARG 72 SER 73 0.0004

SER 73 PRO 74 0.0003

PRO 74 ARG 75 0.0000

ARG 75 LYS 76 0.0000

LYS 76 TRP 77 -0.0003

TRP 77 GLY 78 -0.0123

GLY 78 LEU 79 0.0001

LEU 79 MET 80 0.0000

MET 80 VAL 81 -0.0003

VAL 81 PRO 82 0.0001

PRO 82 ALA 83 0.0001

ALA 83 GLU 84 -0.0001

GLU 84 PHE 85 -0.0003

PHE 85 LEU 86 -0.0005

LEU 86 TYR 87 0.0001

TYR 87 GLU 88 0.0001

GLU 88 PHE 89 0.0036

PHE 89 ILE 90 -0.0002

ILE 90 GLU 91 0.0001

GLU 91 GLU 92 -0.0004

GLU 92 VAL 93 0.0001

VAL 93 ARG 94 0.0002

ARG 94 TYR 95 -0.0002

TYR 95 ARG 96 -0.0000

ARG 96 ILE 97 0.0004

ILE 97 ASN 98 -0.0002

ASN 98 LYS 99 -0.0004

LYS 99 GLY 100 0.0031

GLY 100 LEU 101 0.0004

LEU 101 ARG 102 -0.0003

ARG 102 ILE 103 0.0001

ILE 103 ALA 104 -0.0002

ALA 104 GLU 105 0.0001

GLU 105 GLU 106 -0.0001

GLU 106 HIS 107 -0.0001

HIS 107 ARG 125 0.0006

ARG 125 LEU 126 -0.0002

LEU 126 ARG 127 -0.0000

ARG 127 GLU 128 -0.0002

GLU 128 LYS 129 -0.0001

LYS 129 TYR 130 0.0002

TYR 130 ARG 131 -0.0001

ARG 131 GLU 132 -0.0002

GLU 132 ALA 133 0.0001

ALA 133 LEU 134 0.0001

LEU 134 ARG 135 -0.0004

ARG 135 ALA 136 0.0021

ALA 136 GLY 137 0.0004

GLY 137 ILE 138 -0.0001

ILE 138 ILE 139 0.0001

ILE 139 ASP 140 -0.0001

ASP 140 SER 141 -0.0002

SER 141 LYS 142 -0.0000

LYS 142 GLU 143 0.0004

GLU 143 ASP 144 0.0000

ASP 144 VAL 145 0.0001

VAL 145 ASP 146 0.0003

ASP 146 VAL 147 0.0006

VAL 147 LEU 148 0.0001

LEU 148 LEU 149 -0.0001

LEU 149 LEU 150 -0.0001

LEU 150 SER 151 -0.0001

SER 151 TYR 152 -0.0001

TYR 152 GLU 153 0.0006

GLU 153 LEU 154 -0.0001

LEU 154 ASP 155 0.0000

ASP 155 ALA 156 0.0001

ALA 156 ILE 157 -0.0002

ILE 157 LEU 158 0.0001

LEU 158 VAL 159 0.0003

VAL 159 SER 160 -0.0001

SER 160 GLY 161 0.0001

GLY 161 ASP 162 -0.0000

ASP 162 GLU 163 0.0000

GLU 163 GLY 164 0.0002

GLY 164 LEU 165 -0.0002

LEU 165 ARG 166 -0.0004

ARG 166 LYS 167 0.0001

LYS 167 TRP 168 -0.0000

TRP 168 ALA 169 -0.0020

ALA 169 ASP 170 -0.0000

ASP 170 ARG 171 0.0000

ARG 171 VAL 172 0.0003

VAL 172 GLY 173 0.0001

GLY 173 ILE 174 0.0002

ILE 174 LYS 175 -0.0001

LYS 175 LEU 176 -0.0003

LEU 176 ILE 177 -0.0003

ILE 177 ASP 178 0.0002

ASP 178 PRO 179 -0.0003

PRO 179 LYS 180 0.0025

LYS 180 ASN 181 -0.0002

ASN 181 LEU 182 -0.0002

LEU 182 ARG 183 -0.0003

ARG 183 TYR 184 -0.0001

TYR 184 ILE 185 0.0000

ILE 185 MET 186 0.0001

MET 186 GLU 187 -0.0001

GLU 187 ASN 188 0.0001

ASN 188 LEU 189 0.0002

LEU 189 THR 190 0.0000

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** ***

CA strain for 22121317404857062

--- normal mode 7 ---

Should you encounter any unexpected behaviour,
please let us know.

* *