Should you encounter any unexpected behaviour,
please let us know.

* nome *

CA strain for 221129135925108001

--- normal mode 7 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
ALA 27 TYR 28 -0.0001

TYR 28 THR 29 0.0003

THR 29 ASN 30 -0.0003

ASN 30 SER 31 -0.0000

SER 31 PHE 32 0.0000

PHE 32 THR 33 0.0004

THR 33 ARG 34 0.0001

ARG 34 GLY 35 0.0002

GLY 35 VAL 36 -0.0001

VAL 36 TYR 37 0.0001

TYR 37 TYR 38 0.0000

TYR 38 PRO 39 0.0002

PRO 39 ASP 40 0.0001

ASP 40 LYS 41 -0.0002

LYS 41 VAL 42 -0.0226

VAL 42 PHE 43 -0.0000

PHE 43 ARG 44 0.0003

ARG 44 SER 45 -0.0003

SER 45 SER 46 0.0003

SER 46 VAL 47 -0.0003

VAL 47 LEU 48 0.0001

LEU 48 HIS 49 0.0000

HIS 49 SER 50 -0.0001

SER 50 THR 51 -0.0002

THR 51 GLN 52 -0.0001

GLN 52 ASP 53 0.0001

ASP 53 LEU 54 0.0001

LEU 54 PHE 55 -0.0001

PHE 55 LEU 56 0.0003

LEU 56 PRO 57 -0.0085

PRO 57 PHE 58 -0.0000

PHE 58 PHE 59 0.0001

PHE 59 SER 60 -0.0002

SER 60 ASN 61 -0.0002

ASN 61 VAL 62 -0.0000

VAL 62 THR 63 -0.0003

THR 63 TRP 64 0.0001

TRP 64 PHE 65 -0.0002

PHE 65 HIS 66 -0.0002

HIS 66 ALA 67 0.0003

ALA 67 ILE 68 0.0000

ILE 68 HIS 69 -0.0000

HIS 69 ASP 80 -0.0008

ASP 80 ASN 81 -0.0001

ASN 81 PRO 82 -0.0000

PRO 82 VAL 83 -0.0000

VAL 83 LEU 84 -0.0001

LEU 84 PRO 85 0.0002

PRO 85 PHE 86 0.0002

PHE 86 ASN 87 -0.0004

ASN 87 ASP 88 0.0003

ASP 88 GLY 89 0.0005

GLY 89 VAL 90 -0.0003

VAL 90 TYR 91 0.0002

TYR 91 PHE 92 0.0002

PHE 92 ALA 93 0.0002

ALA 93 SER 94 -0.0000

SER 94 THR 95 -0.0016

THR 95 GLU 96 0.0001

GLU 96 LYS 97 0.0000

LYS 97 SER 98 0.0004

SER 98 ASN 99 -0.0000

ASN 99 ILE 100 -0.0002

ILE 100 ILE 101 -0.0001

ILE 101 ARG 102 0.0002

ARG 102 GLY 103 -0.0000

GLY 103 TRP 104 0.0003

TRP 104 ILE 105 0.0000

ILE 105 PHE 106 0.0001

PHE 106 GLY 107 -0.0003

GLY 107 THR 108 0.0000

THR 108 THR 109 0.0002

THR 109 LEU 110 0.0007

LEU 110 ASP 111 0.0000

ASP 111 SER 112 -0.0000

SER 112 LYS 113 0.0002

LYS 113 THR 114 -0.0001

THR 114 GLN 115 -0.0000

GLN 115 SER 116 0.0001

SER 116 LEU 117 -0.0003

LEU 117 LEU 118 0.0002

LEU 118 ILE 119 -0.0006

ILE 119 VAL 120 0.0003

VAL 120 ASN 121 0.0001

ASN 121 ASN 122 0.0000

ASN 122 ALA 123 -0.0001

ALA 123 THR 124 -0.0001

THR 124 ASN 125 0.0009

ASN 125 VAL 126 0.0004

VAL 126 VAL 127 -0.0004

VAL 127 ILE 128 -0.0001

ILE 128 LYS 129 0.0006

LYS 129 VAL 130 -0.0002

VAL 130 CYS 131 0.0003

CYS 131 GLU 132 -0.0002

GLU 132 PHE 133 -0.0002

PHE 133 GLN 134 -0.0003

GLN 134 PHE 135 -0.0001

PHE 135 CYS 136 0.0001

CYS 136 ASN 137 -0.0003

ASN 137 ASP 138 -0.0000

ASP 138 PRO 139 -0.0000

PRO 139 PHE 140 -0.0010

PHE 140 LEU 141 0.0001

LEU 141 GLY 142 -0.0003

GLY 142 VAL 143 -0.0000

VAL 143 ASN 165 0.0002

ASN 165 CYS 166 0.0001

CYS 166 THR 167 0.0003

THR 167 PHE 168 -0.0005

PHE 168 GLU 169 0.0002

GLU 169 TYR 170 0.0002

TYR 170 VAL 171 0.0002

VAL 171 SER 172 -0.0002

SER 172 PHE 186 0.0018

PHE 186 LYS 187 -0.0000

LYS 187 ASN 188 -0.0002

ASN 188 LEU 189 -0.0001

LEU 189 ARG 190 -0.0001

ARG 190 GLU 191 -0.0002

GLU 191 PHE 192 0.0001

PHE 192 VAL 193 0.0002

VAL 193 PHE 194 -0.0000

PHE 194 LYS 195 -0.0001

LYS 195 ASN 196 0.0002

ASN 196 ILE 197 0.0001

ILE 197 ASP 198 0.0001

ASP 198 GLY 199 -0.0005

GLY 199 TYR 200 0.0001

TYR 200 PHE 201 0.0045

PHE 201 LYS 202 -0.0002

LYS 202 ILE 203 -0.0002

ILE 203 TYR 204 0.0005

TYR 204 SER 205 -0.0001

SER 205 LYS 206 -0.0000

LYS 206 HIS 207 -0.0003

HIS 207 THR 208 0.0000

THR 208 PRO 209 -0.0000

PRO 209 ILE 210 -0.0000

ILE 210 ASN 211 0.0003

ASN 211 LEU 212 -0.0002

LEU 212 VAL 213 -0.0003

VAL 213 ARG 214 -0.0003

ARG 214 ASP 215 -0.0003

ASP 215 LEU 216 -0.0110

LEU 216 PRO 217 0.0005

PRO 217 GLN 218 -0.0000

GLN 218 GLY 219 0.0001

GLY 219 PHE 220 0.0001

PHE 220 SER 221 0.0004

SER 221 ALA 222 -0.0003

ALA 222 LEU 223 0.0000

LEU 223 GLU 224 -0.0001

GLU 224 PRO 225 0.0000

PRO 225 LEU 226 -0.0002

LEU 226 VAL 227 0.0004

VAL 227 ASP 228 -0.0001

ASP 228 LEU 229 -0.0000

LEU 229 PRO 230 -0.0001

PRO 230 ILE 231 -0.0183

ILE 231 GLY 232 0.0000

GLY 232 ILE 233 -0.0000

ILE 233 ASN 234 -0.0002

ASN 234 ILE 235 0.0001

ILE 235 THR 236 -0.0004

THR 236 ARG 237 0.0000

ARG 237 PHE 238 -0.0000

PHE 238 GLN 239 -0.0001

GLN 239 THR 240 -0.0001

THR 240 LEU 241 0.0002

LEU 241 LEU 242 -0.0001

LEU 242 ALA 243 -0.0000

ALA 243 LEU 244 0.0002

LEU 244 HIS 245 0.0001

HIS 245 ALA 263 0.0020

ALA 263 ALA 264 -0.0002

ALA 264 TYR 265 0.0000

TYR 265 TYR 266 0.0001

TYR 266 VAL 267 0.0002

VAL 267 GLY 268 0.0000

GLY 268 TYR 269 0.0001

TYR 269 LEU 270 -0.0002

LEU 270 GLN 271 0.0004

GLN 271 PRO 272 -0.0002

PRO 272 ARG 273 -0.0001

ARG 273 THR 274 0.0001

THR 274 PHE 275 0.0002

PHE 275 LEU 276 -0.0001

LEU 276 LEU 277 -0.0003

LEU 277 LYS 278 0.0016

LYS 278 TYR 279 -0.0000

TYR 279 ASN 280 -0.0001

ASN 280 GLU 281 -0.0002

GLU 281 ASN 282 0.0001

ASN 282 GLY 283 -0.0001

GLY 283 THR 284 0.0003

THR 284 ILE 285 -0.0003

ILE 285 THR 286 0.0001

THR 286 ASP 287 0.0001

ASP 287 ALA 288 -0.0001

ALA 288 VAL 289 0.0002

VAL 289 ASP 290 0.0000

ASP 290 CYS 291 0.0001

CYS 291 ALA 292 -0.0004

ALA 292 LEU 293 -0.0449

LEU 293 ASP 294 -0.0003

ASP 294 PRO 295 -0.0004

PRO 295 LEU 296 0.0003

LEU 296 SER 297 -0.0002

SER 297 GLU 298 -0.0001

GLU 298 THR 299 -0.0001

THR 299 LYS 300 -0.0003

LYS 300 CYS 301 0.0002

CYS 301 THR 302 0.0001

THR 302 LEU 303 -0.0002

LEU 303 LYS 304 -0.0002

LYS 304 SER 305 0.0000

SER 305 PHE 306 -0.0001

PHE 306 THR 307 0.0001

THR 307 VAL 308 0.0005

VAL 308 GLU 309 0.0004

GLU 309 LYS 310 -0.0001

LYS 310 GLY 311 0.0002

GLY 311 ILE 312 -0.0001

ILE 312 TYR 313 0.0003

TYR 313 GLN 314 -0.0005

GLN 314 THR 315 0.0003

THR 315 SER 316 0.0001

SER 316 ASN 317 0.0002

ASN 317 PHE 318 0.0001

PHE 318 ARG 319 0.0002

ARG 319 VAL 320 0.0001

VAL 320 GLN 321 0.0001

GLN 321 PRO 322 -0.0002

PRO 322 THR 323 -0.0181

THR 323 GLU 324 -0.0001

GLU 324 SER 325 -0.0000

SER 325 ILE 326 0.0000

ILE 326 VAL 327 -0.0004

VAL 327 ARG 328 0.0004

ARG 328 PHE 329 -0.0000

PHE 329 PRO 330 -0.0000

PRO 330 ASN 331 0.0001

ASN 331 ILE 332 0.0002

ILE 332 THR 333 -0.0002

THR 333 ASN 334 0.0001

ASN 334 LEU 335 0.0002

LEU 335 CYS 336 -0.0006

CYS 336 PRO 337 0.0004

PRO 337 PHE 338 0.0081

PHE 338 GLY 339 -0.0000

GLY 339 GLU 340 -0.0000

GLU 340 VAL 341 0.0003

VAL 341 PHE 342 0.0002

PHE 342 ASN 343 0.0004

ASN 343 ALA 344 0.0001

ALA 344 THR 345 -0.0001

THR 345 ARG 346 0.0002

ARG 346 PHE 347 -0.0001

PHE 347 ALA 348 0.0002

ALA 348 SER 349 0.0001

SER 349 VAL 350 0.0001

VAL 350 TYR 351 -0.0001

TYR 351 ALA 352 -0.0000

ALA 352 TRP 353 -0.0076

TRP 353 ASN 354 -0.0005

ASN 354 ARG 355 0.0003

ARG 355 LYS 356 -0.0002

LYS 356 ARG 357 -0.0001

ARG 357 ILE 358 -0.0001

ILE 358 SER 359 -0.0001

SER 359 ASN 360 0.0001

ASN 360 CYS 361 -0.0003

CYS 361 VAL 362 0.0003

VAL 362 ALA 363 0.0000

ALA 363 ASP 364 -0.0002

ASP 364 TYR 365 -0.0002

TYR 365 SER 366 -0.0002

SER 366 VAL 367 -0.0002

VAL 367 LEU 368 -0.0168

LEU 368 TYR 369 -0.0004

TYR 369 ASN 370 -0.0000

ASN 370 SER 371 0.0001

SER 371 ALA 372 -0.0001

ALA 372 SER 373 0.0001

SER 373 PHE 374 -0.0003

PHE 374 SER 375 -0.0002

SER 375 THR 376 -0.0004

THR 376 PHE 377 -0.0001

PHE 377 LYS 378 0.0002

LYS 378 CYS 379 -0.0002

CYS 379 TYR 380 0.0005

TYR 380 GLY 381 -0.0001

GLY 381 VAL 382 -0.0000

VAL 382 SER 383 -0.0015

SER 383 PRO 384 0.0004

PRO 384 THR 385 0.0001

THR 385 LYS 386 -0.0003

LYS 386 LEU 387 0.0001

LEU 387 ASN 388 -0.0001

ASN 388 ASP 389 -0.0000

ASP 389 LEU 390 -0.0001

LEU 390 CYS 391 0.0002

CYS 391 PHE 392 -0.0003

PHE 392 THR 393 -0.0001

THR 393 ASN 394 -0.0001

ASN 394 VAL 395 0.0001

VAL 395 TYR 396 0.0003

TYR 396 ALA 397 0.0001

ALA 397 ASP 398 -0.0036

ASP 398 SER 399 0.0002

SER 399 PHE 400 -0.0000

PHE 400 VAL 401 -0.0000

VAL 401 ILE 402 0.0000

ILE 402 ARG 403 -0.0001

ARG 403 GLY 404 0.0000

GLY 404 ASP 405 0.0003

ASP 405 GLU 406 0.0000

GLU 406 VAL 407 0.0000

VAL 407 ARG 408 0.0004

ARG 408 GLN 409 -0.0003

GLN 409 ILE 410 -0.0002

ILE 410 ALA 411 -0.0002

ALA 411 PRO 412 -0.0000

PRO 412 GLY 413 0.0038

GLY 413 GLN 414 0.0001

GLN 414 THR 415 0.0002

THR 415 GLY 416 -0.0001

GLY 416 LYS 417 -0.0002

LYS 417 ILE 418 0.0001

ILE 418 ALA 419 0.0002

ALA 419 ASP 420 0.0002

ASP 420 TYR 421 -0.0004

TYR 421 ASN 422 -0.0001

ASN 422 TYR 423 -0.0000

TYR 423 LYS 424 -0.0001

LYS 424 LEU 425 -0.0001

LEU 425 PRO 426 0.0003

PRO 426 ASP 427 -0.0004

ASP 427 ASP 428 -0.0022

ASP 428 PHE 429 0.0006

PHE 429 THR 430 -0.0006

THR 430 GLY 431 0.0003

GLY 431 CYS 432 0.0002

CYS 432 VAL 433 -0.0000

VAL 433 ILE 434 -0.0003

ILE 434 ALA 435 -0.0002

ALA 435 TRP 436 -0.0001

TRP 436 ASN 437 0.0003

ASN 437 SER 438 -0.0002

SER 438 ASN 439 0.0002

ASN 439 ASN 440 0.0000

ASN 440 LEU 441 -0.0001

LEU 441 ASP 442 -0.0000

ASP 442 SER 443 -0.0045

SER 443 LYS 444 0.0001

LYS 444 GLY 447 0.0020

GLY 447 ASN 448 0.0001

ASN 448 TYR 449 -0.0003

TYR 449 ASN 450 -0.0002

ASN 450 TYR 451 -0.0000

TYR 451 LEU 452 0.0004

LEU 452 TYR 453 -0.0002

TYR 453 ARG 454 -0.0002

ARG 454 LYS 462 -0.0057

LYS 462 PRO 463 -0.0001

PRO 463 PHE 464 -0.0001

PHE 464 GLU 465 -0.0001

GLU 465 ARG 466 -0.0003

ARG 466 ASP 467 0.0001

ASP 467 ILE 468 0.0000

ILE 468 TYR 489 0.0028

TYR 489 PHE 490 -0.0002

PHE 490 PRO 491 0.0002

PRO 491 LEU 492 -0.0000

LEU 492 GLN 493 -0.0001

GLN 493 SER 494 -0.0003

SER 494 TYR 495 0.0004

TYR 495 GLY 496 0.0002

GLY 496 PHE 497 -0.0002

PHE 497 GLN 498 0.0003

GLN 498 PRO 499 -0.0002

PRO 499 THR 500 0.0002

THR 500 ASN 501 0.0001

ASN 501 VAL 503 0.0035

VAL 503 GLY 504 0.0002

GLY 504 TYR 505 -0.0002

TYR 505 GLN 506 -0.0002

GLN 506 PRO 507 0.0001

PRO 507 TYR 508 0.0000

TYR 508 ARG 509 -0.0001

ARG 509 VAL 510 0.0001

VAL 510 VAL 511 -0.0001

VAL 511 VAL 512 0.0001

VAL 512 LEU 513 -0.0003

LEU 513 SER 514 0.0001

SER 514 PHE 515 0.0001

PHE 515 GLU 516 -0.0002

GLU 516 LEU 517 -0.0002

LEU 517 LEU 518 -0.0163

LEU 518 HIS 519 0.0000

HIS 519 ALA 520 -0.0002

ALA 520 PRO 521 0.0004

PRO 521 ALA 522 0.0001

ALA 522 THR 523 0.0001

THR 523 VAL 524 -0.0002

VAL 524 CYS 525 -0.0000

CYS 525 GLY 526 -0.0001

GLY 526 PRO 527 0.0001

PRO 527 LYS 528 0.0001

LYS 528 LYS 529 -0.0005

LYS 529 SER 530 0.0000

SER 530 THR 531 -0.0000

THR 531 ASN 532 -0.0001

ASN 532 LEU 533 0.0016

LEU 533 VAL 534 0.0001

VAL 534 LYS 535 0.0002

LYS 535 ASN 536 0.0000

ASN 536 LYS 537 -0.0002

LYS 537 CYS 538 0.0000

CYS 538 VAL 539 -0.0003

VAL 539 ASN 540 0.0004

ASN 540 PHE 541 -0.0004

PHE 541 ASN 542 0.0002

ASN 542 PHE 543 0.0000

PHE 543 ASN 544 0.0000

ASN 544 GLY 545 -0.0001

GLY 545 LEU 546 0.0000

LEU 546 THR 547 0.0000

THR 547 GLY 548 -0.0133

GLY 548 THR 549 0.0002

THR 549 GLY 550 -0.0000

GLY 550 VAL 551 0.0003

VAL 551 LEU 552 -0.0002

LEU 552 THR 553 0.0004

THR 553 GLU 554 -0.0002

GLU 554 SER 555 0.0001

SER 555 ASN 556 -0.0001

ASN 556 LYS 557 0.0004

LYS 557 LYS 558 0.0002

LYS 558 PHE 559 -0.0000

PHE 559 LEU 560 0.0004

LEU 560 PRO 561 0.0001

PRO 561 PHE 562 0.0002

PHE 562 GLN 563 -0.0215

GLN 563 GLN 564 -0.0002

GLN 564 PHE 565 -0.0002

PHE 565 GLY 566 0.0001

GLY 566 ARG 567 -0.0002

ARG 567 ASP 568 0.0001

ASP 568 ILE 569 0.0000

ILE 569 ALA 570 0.0001

ALA 570 ASP 571 -0.0001

ASP 571 THR 572 -0.0001

THR 572 THR 573 -0.0001

THR 573 ASP 574 0.0003

ASP 574 ALA 575 0.0001

ALA 575 VAL 576 -0.0000

VAL 576 ARG 577 -0.0002

ARG 577 ASP 578 0.0094

ASP 578 PRO 579 -0.0004

PRO 579 GLN 580 0.0001

GLN 580 THR 581 0.0004

THR 581 LEU 582 -0.0000

LEU 582 GLU 583 0.0001

GLU 583 ILE 584 0.0004

ILE 584 LEU 585 -0.0002

LEU 585 ASP 586 0.0001

ASP 586 ILE 587 -0.0004

ILE 587 THR 588 0.0003

THR 588 PRO 589 -0.0002

PRO 589 CYS 590 0.0001

CYS 590 SER 591 -0.0002

SER 591 PHE 592 0.0003

PHE 592 GLY 593 -0.0305

GLY 593 GLY 594 0.0003

GLY 594 VAL 595 0.0001

VAL 595 SER 596 0.0000

SER 596 VAL 597 -0.0000

VAL 597 ILE 598 0.0004

ILE 598 THR 599 -0.0003

THR 599 PRO 600 0.0003

PRO 600 GLY 601 0.0001

GLY 601 THR 602 0.0001

THR 602 ASN 603 -0.0001

ASN 603 THR 604 0.0002

THR 604 SER 605 0.0001

SER 605 ASN 606 0.0002

ASN 606 GLN 607 -0.0001

GLN 607 VAL 608 0.0040

VAL 608 ALA 609 -0.0001

ALA 609 VAL 610 -0.0001

VAL 610 LEU 611 0.0002

LEU 611 TYR 612 0.0003

TYR 612 GLN 613 -0.0000

GLN 613 ASP 614 0.0000

ASP 614 VAL 615 0.0000

VAL 615 ASN 616 -0.0000

ASN 616 CYS 617 0.0000

CYS 617 THR 618 0.0001

THR 618 GLU 619 0.0001

GLU 619 VAL 620 0.0004

VAL 620 ASN 641 -0.0044

ASN 641 VAL 642 0.0002

VAL 642 PHE 643 -0.0000

PHE 643 GLN 644 -0.0005

GLN 644 THR 645 0.0001

THR 645 ARG 646 -0.0001

ARG 646 ALA 647 0.0002

ALA 647 GLY 648 0.0000

GLY 648 CYS 649 0.0002

CYS 649 LEU 650 0.0003

LEU 650 ILE 651 -0.0000

ILE 651 GLY 652 -0.0002

GLY 652 ALA 653 -0.0000

ALA 653 GLU 654 -0.0000

GLU 654 HIS 655 0.0002

HIS 655 VAL 656 -0.0152

VAL 656 ASN 657 -0.0004

ASN 657 ASN 658 0.0000

ASN 658 SER 659 -0.0003

SER 659 TYR 660 -0.0001

TYR 660 GLU 661 0.0001

GLU 661 CYS 662 -0.0001

CYS 662 ASP 663 -0.0000

ASP 663 ILE 664 -0.0001

ILE 664 PRO 665 0.0003

PRO 665 ILE 666 0.0000

ILE 666 GLY 667 0.0000

GLY 667 ALA 668 0.0003

ALA 668 GLY 669 0.0000

GLY 669 ILE 670 -0.0000

ILE 670 CYS 671 0.0037

CYS 671 ALA 672 0.0002

ALA 672 SER 673 -0.0003

SER 673 TYR 674 0.0005

TYR 674 GLN 675 -0.0002

GLN 675 THR 676 -0.0002

THR 676 SER 689 0.0006

SER 689 GLN 690 0.0003

GLN 690 SER 691 -0.0005

SER 691 ILE 692 0.0003

ILE 692 ILE 693 0.0003

ILE 693 ALA 694 -0.0004

ALA 694 TYR 695 -0.0001

TYR 695 THR 696 0.0002

THR 696 MET 697 -0.0000

MET 697 SER 698 -0.0001

SER 698 LEU 699 -0.0001

LEU 699 GLY 700 0.0002

GLY 700 ALA 701 0.0001

ALA 701 GLU 702 0.0000

GLU 702 ASN 703 0.0000

ASN 703 SER 704 -0.0028

SER 704 VAL 705 -0.0001

VAL 705 ALA 706 -0.0003

ALA 706 TYR 707 0.0001

TYR 707 SER 708 0.0000

SER 708 ASN 709 -0.0002

ASN 709 ASN 710 -0.0000

ASN 710 SER 711 0.0002

SER 711 ILE 712 0.0001

ILE 712 ALA 713 0.0002

ALA 713 ILE 714 0.0002

ILE 714 PRO 715 0.0001

PRO 715 THR 716 -0.0001

THR 716 ASN 717 0.0000

ASN 717 PHE 718 -0.0001

PHE 718 THR 719 0.0051

THR 719 ILE 720 0.0002

ILE 720 SER 721 0.0001

SER 721 VAL 722 0.0000

VAL 722 THR 723 0.0001

THR 723 THR 724 0.0003

THR 724 GLU 725 -0.0000

GLU 725 ILE 726 -0.0001

ILE 726 LEU 727 -0.0001

LEU 727 PRO 728 0.0000

PRO 728 VAL 729 -0.0001

VAL 729 SER 730 0.0002

SER 730 MET 731 0.0001

MET 731 THR 732 -0.0002

THR 732 LYS 733 0.0000

LYS 733 THR 734 0.0295

THR 734 SER 735 0.0003

SER 735 VAL 736 -0.0002

VAL 736 ASP 737 -0.0004

ASP 737 CYS 738 -0.0000

CYS 738 THR 739 0.0000

THR 739 MET 740 -0.0002

MET 740 TYR 741 -0.0001

TYR 741 ILE 742 0.0002

ILE 742 CYS 743 0.0001

CYS 743 GLY 744 0.0002

GLY 744 ASP 745 -0.0004

ASP 745 SER 746 0.0003

SER 746 THR 747 0.0001

THR 747 GLU 748 0.0001

GLU 748 CYS 749 0.0048

CYS 749 SER 750 -0.0002

SER 750 ASN 751 0.0002

ASN 751 LEU 752 0.0004

LEU 752 LEU 753 0.0002

LEU 753 LEU 754 -0.0001

LEU 754 GLN 755 -0.0002

GLN 755 TYR 756 -0.0000

TYR 756 GLY 757 0.0005

GLY 757 SER 758 0.0002

SER 758 PHE 759 -0.0001

PHE 759 CYS 760 0.0000

CYS 760 THR 761 -0.0001

THR 761 GLN 762 0.0002

GLN 762 LEU 763 0.0001

LEU 763 ASN 764 0.0001

ASN 764 ARG 765 0.0004

ARG 765 ALA 766 0.0001

ALA 766 LEU 767 0.0003

LEU 767 THR 768 0.0000

THR 768 GLY 769 -0.0001

GLY 769 ILE 770 0.0000

ILE 770 ALA 771 -0.0002

ALA 771 VAL 772 -0.0002

VAL 772 GLU 773 -0.0001

GLU 773 GLN 774 -0.0004

GLN 774 ASP 775 0.0001

ASP 775 LYS 776 0.0001

LYS 776 ASN 777 0.0002

ASN 777 THR 778 0.0001

THR 778 GLN 779 -0.0033

GLN 779 GLU 780 -0.0001

GLU 780 VAL 781 0.0002

VAL 781 PHE 782 0.0003

PHE 782 ALA 783 -0.0003

ALA 783 GLN 784 0.0002

GLN 784 VAL 785 -0.0003

VAL 785 LYS 786 0.0000

LYS 786 GLN 787 -0.0002

GLN 787 ILE 788 0.0005

ILE 788 TYR 789 -0.0000

TYR 789 LYS 790 -0.0001

LYS 790 THR 791 0.0003

THR 791 PRO 792 -0.0002

PRO 792 PRO 793 0.0002

PRO 793 ILE 794 0.0025

ILE 794 LYS 795 0.0004

LYS 795 ASP 796 -0.0002

ASP 796 PHE 797 0.0002

PHE 797 GLY 798 -0.0000

GLY 798 GLY 799 -0.0002

GLY 799 PHE 800 0.0001

PHE 800 ASN 801 -0.0002

ASN 801 PHE 802 0.0003

PHE 802 SER 803 -0.0000

SER 803 GLN 804 -0.0004

GLN 804 ILE 805 0.0000

ILE 805 LEU 806 -0.0002

LEU 806 PRO 807 0.0000

PRO 807 ASP 808 -0.0001

ASP 808 PRO 809 0.0013

PRO 809 SER 810 -0.0005

SER 810 LYS 811 -0.0002

LYS 811 PRO 812 0.0005

PRO 812 SER 813 0.0003

SER 813 LYS 814 -0.0000

LYS 814 ARG 815 0.0003

ARG 815 SER 816 -0.0002

SER 816 PHE 817 0.0001

PHE 817 ILE 818 -0.0002

ILE 818 GLU 819 0.0003

GLU 819 ASP 820 0.0003

ASP 820 LEU 821 0.0001

LEU 821 LEU 822 0.0001

LEU 822 PHE 823 -0.0002

PHE 823 ASN 824 0.0010

ASN 824 LYS 825 0.0000

LYS 825 VAL 826 0.0002

VAL 826 THR 827 -0.0000

THR 827 LYS 854 0.0055

LYS 854 PHE 855 0.0000

PHE 855 ASN 856 -0.0002

ASN 856 GLY 857 -0.0001

GLY 857 LEU 858 0.0001

LEU 858 THR 859 0.0000

THR 859 VAL 860 -0.0001

VAL 860 LEU 861 -0.0001

LEU 861 PRO 862 0.0003

PRO 862 PRO 863 -0.0003

PRO 863 LEU 864 -0.0002

LEU 864 LEU 865 -0.0001

LEU 865 THR 866 -0.0001

THR 866 ASP 867 -0.0000

ASP 867 GLU 868 0.0003

GLU 868 MET 869 0.0092

MET 869 ILE 870 0.0001

ILE 870 ALA 871 0.0002

ALA 871 GLN 872 0.0002

GLN 872 TYR 873 0.0000

TYR 873 THR 874 -0.0004

THR 874 SER 875 0.0001

SER 875 ALA 876 0.0002

ALA 876 LEU 877 0.0000

LEU 877 LEU 878 -0.0001

LEU 878 ALA 879 -0.0000

ALA 879 GLY 880 -0.0004

GLY 880 THR 881 0.0001

THR 881 ILE 882 -0.0000

ILE 882 THR 883 -0.0003

THR 883 SER 884 -0.0026

SER 884 GLY 885 0.0003

GLY 885 TRP 886 -0.0005

TRP 886 THR 887 -0.0000

THR 887 PHE 888 -0.0001

PHE 888 GLY 889 -0.0002

GLY 889 ALA 890 0.0001

ALA 890 GLY 891 0.0002

GLY 891 ALA 892 -0.0001

ALA 892 ALA 893 0.0001

ALA 893 LEU 894 -0.0000

LEU 894 GLN 895 0.0005

GLN 895 ILE 896 -0.0001

ILE 896 PRO 897 -0.0000

PRO 897 PHE 898 0.0001

PHE 898 ALA 899 0.0067

ALA 899 MET 900 -0.0002

MET 900 GLN 901 -0.0003

GLN 901 MET 902 0.0001

MET 902 ALA 903 -0.0000

ALA 903 TYR 904 -0.0005

TYR 904 ARG 905 -0.0000

ARG 905 PHE 906 0.0002

PHE 906 ASN 907 -0.0002

ASN 907 GLY 908 0.0000

GLY 908 ILE 909 -0.0000

ILE 909 GLY 910 -0.0001

GLY 910 VAL 911 0.0001

VAL 911 THR 912 0.0004

THR 912 GLN 913 -0.0002

GLN 913 ASN 914 0.0008

ASN 914 VAL 915 -0.0000

VAL 915 LEU 916 -0.0000

LEU 916 TYR 917 -0.0003

TYR 917 GLU 918 0.0000

GLU 918 ASN 919 0.0002

ASN 919 GLN 920 -0.0000

GLN 920 LYS 921 0.0002

LYS 921 LEU 922 0.0002

LEU 922 ILE 923 0.0001

ILE 923 ALA 924 0.0001

ALA 924 ASN 925 -0.0003

ASN 925 GLN 926 0.0002

GLN 926 PHE 927 0.0002

PHE 927 ASN 928 0.0001

ASN 928 SER 929 0.0002

SER 929 ALA 930 -0.0002

ALA 930 ILE 931 -0.0002

ILE 931 GLY 932 0.0003

GLY 932 LYS 933 -0.0001

LYS 933 ILE 934 0.0001

ILE 934 GLN 935 -0.0003

GLN 935 ASP 936 -0.0000

ASP 936 SER 937 0.0001

SER 937 LEU 938 -0.0001

LEU 938 SER 939 -0.0000

SER 939 SER 940 0.0003

SER 940 THR 941 -0.0003

THR 941 ALA 942 -0.0003

ALA 942 SER 943 -0.0002

SER 943 ALA 944 0.0042

ALA 944 LEU 945 0.0000

LEU 945 GLY 946 0.0002

GLY 946 LYS 947 -0.0000

LYS 947 LEU 948 -0.0000

LEU 948 GLN 949 -0.0004

GLN 949 ASP 950 0.0002

ASP 950 VAL 951 -0.0001

VAL 951 VAL 952 0.0004

VAL 952 ASN 953 0.0002

ASN 953 GLN 954 -0.0001

GLN 954 ASN 955 -0.0003

ASN 955 ALA 956 -0.0001

ALA 956 GLN 957 -0.0002

GLN 957 ALA 958 -0.0003

ALA 958 LEU 959 0.0073

LEU 959 ASN 960 -0.0002

ASN 960 THR 961 0.0003

THR 961 LEU 962 0.0002

LEU 962 VAL 963 -0.0003

VAL 963 LYS 964 0.0001

LYS 964 GLN 965 0.0001

GLN 965 LEU 966 -0.0001

LEU 966 SER 967 0.0002

SER 967 SER 968 -0.0001

SER 968 ASN 969 -0.0001

ASN 969 PHE 970 0.0000

PHE 970 GLY 971 0.0002

GLY 971 ALA 972 -0.0001

ALA 972 ILE 973 -0.0000

ILE 973 SER 974 0.0053

SER 974 SER 975 0.0002

SER 975 VAL 976 0.0000

VAL 976 LEU 977 0.0000

LEU 977 ASN 978 0.0001

ASN 978 ASP 979 -0.0002

ASP 979 ILE 980 0.0002

ILE 980 LEU 981 0.0001

LEU 981 SER 982 -0.0003

SER 982 ARG 983 -0.0001

ARG 983 LEU 984 -0.0001

LEU 984 ASP 985 -0.0003

ASP 985 PRO 986 0.0001

PRO 986 PRO 987 -0.0002

PRO 987 GLU 988 0.0002

GLU 988 ALA 989 0.0255

ALA 989 GLU 990 -0.0001

GLU 990 VAL 991 0.0000

VAL 991 GLN 992 0.0000

GLN 992 ILE 993 -0.0004

ILE 993 ASP 994 0.0001

ASP 994 ARG 995 -0.0001

ARG 995 LEU 996 0.0001

LEU 996 ILE 997 -0.0001

ILE 997 THR 998 0.0001

THR 998 GLY 999 0.0003

GLY 999 ARG 1000 -0.0002

ARG 1000 LEU 1001 0.0002

LEU 1001 GLN 1002 -0.0004

GLN 1002 SER 1003 -0.0001

SER 1003 LEU 1004 -0.0006

LEU 1004 GLN 1005 -0.0001

GLN 1005 THR 1006 -0.0003

THR 1006 TYR 1007 0.0000

TYR 1007 VAL 1008 0.0001

VAL 1008 THR 1009 -0.0002

THR 1009 GLN 1010 0.0001

GLN 1010 GLN 1011 0.0001

GLN 1011 LEU 1012 0.0000

LEU 1012 ILE 1013 -0.0001

ILE 1013 ARG 1014 0.0001

ARG 1014 ALA 1015 -0.0000

ALA 1015 ALA 1016 -0.0002

ALA 1016 GLU 1017 0.0002

GLU 1017 ILE 1018 -0.0001

ILE 1018 ARG 1019 -0.0007

ARG 1019 ALA 1020 -0.0001

ALA 1020 SER 1021 -0.0000

SER 1021 ALA 1022 -0.0000

ALA 1022 ASN 1023 0.0001

ASN 1023 LEU 1024 -0.0002

LEU 1024 ALA 1025 0.0000

ALA 1025 ALA 1026 0.0000

ALA 1026 THR 1027 -0.0002

THR 1027 LYS 1028 -0.0002

LYS 1028 MET 1029 0.0002

MET 1029 SER 1030 0.0002

SER 1030 GLU 1031 0.0000

GLU 1031 CYS 1032 0.0003

CYS 1032 VAL 1033 -0.0000

VAL 1033 LEU 1034 -0.0009

LEU 1034 GLY 1035 -0.0001

GLY 1035 GLN 1036 -0.0001

GLN 1036 SER 1037 0.0002

SER 1037 LYS 1038 -0.0001

LYS 1038 ARG 1039 -0.0001

ARG 1039 VAL 1040 0.0001

VAL 1040 ASP 1041 -0.0002

ASP 1041 PHE 1042 -0.0002

PHE 1042 CYS 1043 -0.0000

CYS 1043 GLY 1044 -0.0001

GLY 1044 LYS 1045 0.0000

LYS 1045 GLY 1046 -0.0001

GLY 1046 TYR 1047 -0.0001

TYR 1047 HIS 1048 0.0002

HIS 1048 LEU 1049 -0.0100

LEU 1049 MET 1050 -0.0000

MET 1050 SER 1051 -0.0000

SER 1051 PHE 1052 0.0006

PHE 1052 PRO 1053 -0.0003

PRO 1053 GLN 1054 -0.0001

GLN 1054 SER 1055 0.0001

SER 1055 ALA 1056 0.0002

ALA 1056 PRO 1057 -0.0001

PRO 1057 HIS 1058 -0.0000

HIS 1058 GLY 1059 -0.0004

GLY 1059 VAL 1060 0.0002

VAL 1060 VAL 1061 -0.0001

VAL 1061 PHE 1062 0.0000

PHE 1062 LEU 1063 -0.0002

LEU 1063 HIS 1064 0.0093

HIS 1064 VAL 1065 -0.0001

VAL 1065 THR 1066 0.0001

THR 1066 TYR 1067 0.0003

TYR 1067 VAL 1068 -0.0004

VAL 1068 PRO 1069 0.0003

PRO 1069 ALA 1070 -0.0000

ALA 1070 GLN 1071 -0.0001

GLN 1071 GLU 1072 0.0001

GLU 1072 LYS 1073 0.0001

LYS 1073 ASN 1074 -0.0002

ASN 1074 PHE 1075 0.0001

PHE 1075 THR 1076 0.0002

THR 1076 THR 1077 -0.0005

THR 1077 ALA 1078 0.0000

ALA 1078 PRO 1079 -0.0033

PRO 1079 ALA 1080 -0.0000

ALA 1080 ILE 1081 -0.0000

ILE 1081 CYS 1082 -0.0002

CYS 1082 HIS 1083 -0.0002

HIS 1083 ASP 1084 0.0000

ASP 1084 GLY 1085 -0.0001

GLY 1085 LYS 1086 -0.0003

LYS 1086 ALA 1087 -0.0000

ALA 1087 HIS 1088 -0.0004

HIS 1088 PHE 1089 0.0004

PHE 1089 PRO 1090 -0.0002

PRO 1090 ARG 1091 0.0003

ARG 1091 GLU 1092 -0.0004

GLU 1092 GLY 1093 0.0004

GLY 1093 VAL 1094 -0.0051

VAL 1094 PHE 1095 -0.0002

PHE 1095 VAL 1096 0.0001

VAL 1096 SER 1097 -0.0001

SER 1097 ASN 1098 -0.0001

ASN 1098 GLY 1099 0.0002

GLY 1099 THR 1100 -0.0003

THR 1100 HIS 1101 0.0003

HIS 1101 TRP 1102 0.0001

TRP 1102 PHE 1103 -0.0001

PHE 1103 VAL 1104 0.0002

VAL 1104 THR 1105 -0.0002

THR 1105 GLN 1106 0.0004

GLN 1106 ARG 1107 0.0001

ARG 1107 ASN 1108 0.0000

ASN 1108 PHE 1109 -0.0014

PHE 1109 TYR 1110 0.0002

TYR 1110 GLU 1111 -0.0001

GLU 1111 PRO 1112 -0.0000

PRO 1112 GLN 1113 0.0001

GLN 1113 ILE 1114 -0.0003

ILE 1114 ILE 1115 0.0001

ILE 1115 THR 1116 0.0001

THR 1116 THR 1117 -0.0000

THR 1117 ASP 1118 -0.0003

ASP 1118 ASN 1119 0.0003

ASN 1119 THR 1120 0.0000

THR 1120 PHE 1121 -0.0004

PHE 1121 VAL 1122 -0.0002

VAL 1122 SER 1123 0.0003

SER 1123 GLY 1124 -0.0005

GLY 1124 ASN 1125 0.0001

ASN 1125 CYS 1126 0.0000

CYS 1126 ASP 1127 -0.0000

ASP 1127 VAL 1128 0.0000

VAL 1128 VAL 1129 0.0002

VAL 1129 ILE 1130 0.0000

ILE 1130 GLY 1131 0.0002

GLY 1131 ILE 1132 -0.0003

ILE 1132 VAL 1133 0.0001

VAL 1133 ASN 1134 0.0000

ASN 1134 ASN 1135 0.0003

ASN 1135 THR 1136 -0.0002

THR 1136 VAL 1137 0.0001

VAL 1137 TYR 1138 0.0001

TYR 1138 ASP 1139 -0.0096

ASP 1139 PRO 1140 -0.0001

PRO 1140 LEU 1141 0.0002

LEU 1141 GLN 1142 -0.0004

GLN 1142 PRO 1143 0.0005

PRO 1143 GLU 1144 0.0003

GLU 1144 LEU 1145 -0.0001

LEU 1145 ASP 1146 -0.0001

ASP 1146 SER 1147 -0.0000

SER 1147 ALA 27 -0.0100

ALA 27 TYR 28 0.0002

TYR 28 THR 29 -0.0000

THR 29 ASN 30 0.0002

ASN 30 SER 31 0.0001

SER 31 PHE 32 0.0004

PHE 32 THR 33 -0.0001

THR 33 ARG 34 -0.0002

ARG 34 GLY 35 0.0000

GLY 35 VAL 36 0.0002

VAL 36 TYR 37 0.0003

TYR 37 TYR 38 -0.0003

TYR 38 PRO 39 -0.0001

PRO 39 ASP 40 0.0000

ASP 40 LYS 41 -0.0001

LYS 41 VAL 42 -0.0211

VAL 42 PHE 43 -0.0002

PHE 43 ARG 44 0.0001

ARG 44 SER 45 -0.0002

SER 45 SER 46 0.0000

SER 46 VAL 47 -0.0003

VAL 47 LEU 48 0.0001

LEU 48 HIS 49 -0.0002

HIS 49 SER 50 -0.0000

SER 50 THR 51 0.0004

THR 51 GLN 52 -0.0003

GLN 52 ASP 53 0.0003

ASP 53 LEU 54 -0.0005

LEU 54 PHE 55 0.0002

PHE 55 LEU 56 -0.0003

LEU 56 PRO 57 -0.0085

PRO 57 PHE 58 0.0002

PHE 58 PHE 59 -0.0003

PHE 59 SER 60 0.0003

SER 60 ASN 61 0.0002

ASN 61 VAL 62 0.0001

VAL 62 THR 63 0.0001

THR 63 TRP 64 -0.0002

TRP 64 PHE 65 0.0004

PHE 65 HIS 66 0.0000

HIS 66 ALA 67 -0.0000

ALA 67 ILE 68 -0.0001

ILE 68 HIS 69 0.0000

HIS 69 ASP 80 0.0013

ASP 80 ASN 81 0.0002

ASN 81 PRO 82 -0.0000

PRO 82 VAL 83 -0.0001

VAL 83 LEU 84 0.0000

LEU 84 PRO 85 0.0004

PRO 85 PHE 86 0.0001

PHE 86 ASN 87 -0.0002

ASN 87 ASP 88 0.0003

ASP 88 GLY 89 0.0002

GLY 89 VAL 90 0.0000

VAL 90 TYR 91 0.0002

TYR 91 PHE 92 0.0003

PHE 92 ALA 93 0.0001

ALA 93 SER 94 -0.0001

SER 94 THR 95 0.0005

THR 95 GLU 96 -0.0003

GLU 96 LYS 97 0.0003

LYS 97 SER 98 -0.0000

SER 98 ASN 99 -0.0001

ASN 99 ILE 100 -0.0002

ILE 100 ILE 101 -0.0000

ILE 101 ARG 102 -0.0000

ARG 102 GLY 103 -0.0002

GLY 103 TRP 104 0.0002

TRP 104 ILE 105 -0.0002

ILE 105 PHE 106 0.0001

PHE 106 GLY 107 -0.0003

GLY 107 THR 108 -0.0000

THR 108 THR 109 0.0002

THR 109 LEU 110 0.0025

LEU 110 ASP 111 -0.0000

ASP 111 SER 112 0.0001

SER 112 LYS 113 -0.0002

LYS 113 THR 114 0.0001

THR 114 GLN 115 0.0000

GLN 115 SER 116 -0.0001

SER 116 LEU 117 -0.0000

LEU 117 LEU 118 0.0003

LEU 118 ILE 119 -0.0003

ILE 119 VAL 120 0.0000

VAL 120 ASN 121 0.0005

ASN 121 ASN 122 -0.0005

ASN 122 ALA 123 0.0001

ALA 123 THR 124 -0.0005

THR 124 ASN 125 -0.0007

ASN 125 VAL 126 0.0003

VAL 126 VAL 127 0.0002

VAL 127 ILE 128 -0.0003

ILE 128 LYS 129 0.0005

LYS 129 VAL 130 -0.0001

VAL 130 CYS 131 0.0000

CYS 131 GLU 132 0.0000

GLU 132 PHE 133 0.0000

PHE 133 GLN 134 -0.0002

GLN 134 PHE 135 -0.0003

PHE 135 CYS 136 0.0004

CYS 136 ASN 137 -0.0002

ASN 137 ASP 138 0.0000

ASP 138 PRO 139 -0.0005

PRO 139 PHE 140 -0.0023

PHE 140 LEU 141 0.0001

LEU 141 GLY 142 -0.0002

GLY 142 VAL 143 0.0002

VAL 143 ASN 165 0.0002

ASN 165 CYS 166 0.0003

CYS 166 THR 167 0.0000

THR 167 PHE 168 -0.0002

PHE 168 GLU 169 -0.0002

GLU 169 TYR 170 -0.0000

TYR 170 VAL 171 0.0001

VAL 171 SER 172 0.0001

SER 172 PHE 186 -0.0009

PHE 186 LYS 187 -0.0001

LYS 187 ASN 188 0.0002

ASN 188 LEU 189 -0.0004

LEU 189 ARG 190 0.0002

ARG 190 GLU 191 -0.0000

GLU 191 PHE 192 -0.0003

PHE 192 VAL 193 0.0004

VAL 193 PHE 194 0.0002

PHE 194 LYS 195 -0.0001

LYS 195 ASN 196 0.0004

ASN 196 ILE 197 -0.0005

ILE 197 ASP 198 0.0001

ASP 198 GLY 199 0.0002

GLY 199 TYR 200 0.0001

TYR 200 PHE 201 0.0026

PHE 201 LYS 202 0.0002

LYS 202 ILE 203 0.0001

ILE 203 TYR 204 -0.0004

TYR 204 SER 205 0.0003

SER 205 LYS 206 -0.0002

LYS 206 HIS 207 -0.0000

HIS 207 THR 208 0.0000

THR 208 PRO 209 0.0000

PRO 209 ILE 210 -0.0001

ILE 210 ASN 211 -0.0003

ASN 211 LEU 212 0.0003

LEU 212 VAL 213 -0.0004

VAL 213 ARG 214 0.0004

ARG 214 ASP 215 0.0004

ASP 215 LEU 216 -0.0069

LEU 216 PRO 217 -0.0001

PRO 217 GLN 218 -0.0004

GLN 218 GLY 219 0.0000

GLY 219 PHE 220 -0.0001

PHE 220 SER 221 0.0001

SER 221 ALA 222 -0.0001

ALA 222 LEU 223 0.0001

LEU 223 GLU 224 0.0004

GLU 224 PRO 225 0.0000

PRO 225 LEU 226 -0.0001

LEU 226 VAL 227 0.0004

VAL 227 ASP 228 0.0001

ASP 228 LEU 229 -0.0000

LEU 229 PRO 230 -0.0001

PRO 230 ILE 231 -0.0050

ILE 231 GLY 232 -0.0002

GLY 232 ILE 233 -0.0002

ILE 233 ASN 234 0.0000

ASN 234 ILE 235 0.0002

ILE 235 THR 236 0.0001

THR 236 ARG 237 -0.0000

ARG 237 PHE 238 -0.0001

PHE 238 GLN 239 0.0001

GLN 239 THR 240 -0.0000

THR 240 LEU 241 0.0001

LEU 241 LEU 242 0.0001

LEU 242 ALA 243 0.0002

ALA 243 LEU 244 -0.0001

LEU 244 HIS 245 0.0004

HIS 245 ALA 263 -0.0004

ALA 263 ALA 264 0.0005

ALA 264 TYR 265 -0.0002

TYR 265 TYR 266 0.0000

TYR 266 VAL 267 0.0002

VAL 267 GLY 268 -0.0002

GLY 268 TYR 269 -0.0002

TYR 269 LEU 270 -0.0002

LEU 270 GLN 271 -0.0002

GLN 271 PRO 272 0.0002

PRO 272 ARG 273 0.0004

ARG 273 THR 274 -0.0003

THR 274 PHE 275 0.0002

PHE 275 LEU 276 -0.0000

LEU 276 LEU 277 -0.0002

LEU 277 LYS 278 -0.0023

LYS 278 TYR 279 -0.0000

TYR 279 ASN 280 0.0000

ASN 280 GLU 281 -0.0002

GLU 281 ASN 282 0.0001

ASN 282 GLY 283 0.0003

GLY 283 THR 284 0.0004

THR 284 ILE 285 -0.0004

ILE 285 THR 286 -0.0001

THR 286 ASP 287 -0.0001

ASP 287 ALA 288 0.0001

ALA 288 VAL 289 0.0003

VAL 289 ASP 290 -0.0002

ASP 290 CYS 291 0.0001

CYS 291 ALA 292 0.0001

ALA 292 LEU 293 -0.0542

LEU 293 ASP 294 -0.0001

ASP 294 PRO 295 -0.0001

PRO 295 LEU 296 0.0004

LEU 296 SER 297 0.0002

SER 297 GLU 298 0.0004

GLU 298 THR 299 -0.0002

THR 299 LYS 300 0.0003

LYS 300 CYS 301 -0.0001

CYS 301 THR 302 -0.0002

THR 302 LEU 303 0.0001

LEU 303 LYS 304 0.0003

LYS 304 SER 305 -0.0000

SER 305 PHE 306 -0.0001

PHE 306 THR 307 -0.0002

THR 307 VAL 308 -0.0522

VAL 308 GLU 309 -0.0003

GLU 309 LYS 310 0.0004

LYS 310 GLY 311 -0.0002

GLY 311 ILE 312 0.0002

ILE 312 TYR 313 0.0000

TYR 313 GLN 314 0.0003

GLN 314 THR 315 0.0002

THR 315 SER 316 -0.0001

SER 316 ASN 317 -0.0001

ASN 317 PHE 318 0.0001

PHE 318 ARG 319 0.0003

ARG 319 VAL 320 -0.0000

VAL 320 GLN 321 -0.0001

GLN 321 PRO 322 -0.0001

PRO 322 THR 323 -0.0057

THR 323 GLU 324 0.0000

GLU 324 SER 325 -0.0003

SER 325 ILE 326 -0.0001

ILE 326 VAL 327 -0.0003

VAL 327 ARG 328 0.0002

ARG 328 PHE 329 -0.0003

PHE 329 PRO 330 -0.0002

PRO 330 ASN 331 0.0000

ASN 331 ILE 332 0.0001

ILE 332 THR 333 -0.0000

THR 333 ASN 334 0.0000

ASN 334 LEU 335 -0.0000

LEU 335 CYS 336 -0.0001

CYS 336 PRO 337 0.0002

PRO 337 PHE 338 0.0073

PHE 338 GLY 339 0.0001

GLY 339 GLU 340 0.0001

GLU 340 VAL 341 0.0002

VAL 341 PHE 342 -0.0000

PHE 342 ASN 343 0.0001

ASN 343 ALA 344 -0.0002

ALA 344 THR 345 0.0003

THR 345 ARG 346 -0.0000

ARG 346 PHE 347 -0.0002

PHE 347 ALA 348 0.0002

ALA 348 SER 349 0.0000

SER 349 VAL 350 0.0002

VAL 350 TYR 351 0.0002

TYR 351 ALA 352 0.0001

ALA 352 TRP 353 -0.0002

TRP 353 ASN 354 -0.0000

ASN 354 ARG 355 -0.0001

ARG 355 LYS 356 -0.0002

LYS 356 ARG 357 0.0002

ARG 357 ILE 358 0.0000

ILE 358 SER 359 0.0003

SER 359 ASN 360 -0.0004

ASN 360 CYS 361 0.0001

CYS 361 VAL 362 -0.0003

VAL 362 ALA 363 0.0002

ALA 363 ASP 364 -0.0005

ASP 364 TYR 365 -0.0001

TYR 365 SER 366 0.0001

SER 366 VAL 367 0.0002

VAL 367 LEU 368 -0.0051

LEU 368 TYR 369 -0.0001

TYR 369 ASN 370 0.0002

ASN 370 SER 371 -0.0001

SER 371 ALA 372 0.0004

ALA 372 SER 373 0.0003

SER 373 PHE 374 -0.0001

PHE 374 SER 375 0.0001

SER 375 THR 376 0.0001

THR 376 PHE 377 0.0001

PHE 377 LYS 378 0.0003

LYS 378 CYS 379 -0.0002

CYS 379 TYR 380 -0.0002

TYR 380 GLY 381 -0.0004

GLY 381 VAL 382 -0.0000

VAL 382 SER 383 0.0052

SER 383 PRO 384 0.0000

PRO 384 THR 385 -0.0002

THR 385 LYS 386 -0.0000

LYS 386 LEU 387 -0.0003

LEU 387 ASN 388 -0.0002

ASN 388 ASP 389 -0.0002

ASP 389 LEU 390 -0.0000

LEU 390 CYS 391 -0.0001

CYS 391 PHE 392 -0.0002

PHE 392 THR 393 0.0003

THR 393 ASN 394 0.0002

ASN 394 VAL 395 -0.0002

VAL 395 TYR 396 0.0000

TYR 396 ALA 397 0.0003

ALA 397 ASP 398 -0.0146

ASP 398 SER 399 -0.0004

SER 399 PHE 400 0.0001

PHE 400 VAL 401 0.0001

VAL 401 ILE 402 -0.0000

ILE 402 ARG 403 -0.0003

ARG 403 GLY 404 -0.0000

GLY 404 ASP 405 -0.0001

ASP 405 GLU 406 0.0002

GLU 406 VAL 407 -0.0001

VAL 407 ARG 408 0.0004

ARG 408 GLN 409 -0.0001

GLN 409 ILE 410 0.0001

ILE 410 ALA 411 -0.0000

ALA 411 PRO 412 0.0004

PRO 412 GLY 413 0.0034

GLY 413 GLN 414 0.0001

GLN 414 THR 415 0.0003

THR 415 GLY 416 -0.0002

GLY 416 LYS 417 0.0002

LYS 417 ILE 418 -0.0002

ILE 418 ALA 419 -0.0003

ALA 419 ASP 420 0.0004

ASP 420 TYR 421 -0.0002

TYR 421 ASN 422 -0.0004

ASN 422 TYR 423 -0.0000

TYR 423 LYS 424 -0.0005

LYS 424 LEU 425 0.0003

LEU 425 PRO 426 0.0002

PRO 426 ASP 427 0.0001

ASP 427 ASP 428 -0.0088

ASP 428 PHE 429 -0.0002

PHE 429 THR 430 -0.0002

THR 430 GLY 431 0.0002

GLY 431 CYS 432 -0.0003

CYS 432 VAL 433 0.0004

VAL 433 ILE 434 -0.0002

ILE 434 ALA 435 -0.0001

ALA 435 TRP 436 0.0001

TRP 436 ASN 437 -0.0003

ASN 437 SER 438 0.0003

SER 438 ASN 439 -0.0003

ASN 439 ASN 440 0.0001

ASN 440 LEU 441 -0.0000

LEU 441 ASP 442 0.0004

ASP 442 SER 443 0.0034

SER 443 LYS 444 -0.0001

LYS 444 GLY 447 -0.0010

GLY 447 ASN 448 0.0002

ASN 448 TYR 449 0.0001

TYR 449 ASN 450 0.0002

ASN 450 TYR 451 0.0003

TYR 451 LEU 452 -0.0002

LEU 452 TYR 453 0.0001

TYR 453 ARG 454 0.0000

ARG 454 LYS 462 0.0088

LYS 462 PRO 463 -0.0003

PRO 463 PHE 464 0.0004

PHE 464 GLU 465 0.0000

GLU 465 ARG 466 0.0001

ARG 466 ASP 467 -0.0000

ASP 467 ILE 468 -0.0001

ILE 468 TYR 489 -0.0062

TYR 489 PHE 490 -0.0002

PHE 490 PRO 491 0.0000

PRO 491 LEU 492 -0.0004

LEU 492 GLN 493 0.0001

GLN 493 SER 494 0.0001

SER 494 TYR 495 -0.0000

TYR 495 GLY 496 0.0003

GLY 496 PHE 497 -0.0001

PHE 497 GLN 498 0.0003

GLN 498 PRO 499 -0.0002

PRO 499 THR 500 0.0002

THR 500 ASN 501 -0.0000

ASN 501 VAL 503 -0.0069

VAL 503 GLY 504 0.0003

GLY 504 TYR 505 -0.0000

TYR 505 GLN 506 -0.0001

GLN 506 PRO 507 0.0001

PRO 507 TYR 508 0.0001

TYR 508 ARG 509 -0.0002

ARG 509 VAL 510 -0.0002

VAL 510 VAL 511 0.0002

VAL 511 VAL 512 0.0002

VAL 512 LEU 513 -0.0001

LEU 513 SER 514 0.0004

SER 514 PHE 515 -0.0004

PHE 515 GLU 516 0.0001

GLU 516 LEU 517 -0.0001

LEU 517 LEU 518 0.0101

LEU 518 HIS 519 0.0002

HIS 519 ALA 520 -0.0001

ALA 520 PRO 521 0.0003

PRO 521 ALA 522 0.0003

ALA 522 THR 523 -0.0002

THR 523 VAL 524 0.0000

VAL 524 CYS 525 -0.0002

CYS 525 GLY 526 0.0003

GLY 526 PRO 527 -0.0001

PRO 527 LYS 528 0.0001

LYS 528 LYS 529 -0.0001

LYS 529 SER 530 -0.0001

SER 530 THR 531 0.0000

THR 531 ASN 532 -0.0003

ASN 532 LEU 533 -0.0109

LEU 533 VAL 534 0.0001

VAL 534 LYS 535 -0.0000

LYS 535 ASN 536 0.0001

ASN 536 LYS 537 -0.0000

LYS 537 CYS 538 -0.0001

CYS 538 VAL 539 -0.0001

VAL 539 ASN 540 0.0001

ASN 540 PHE 541 -0.0001

PHE 541 ASN 542 -0.0002

ASN 542 PHE 543 0.0002

PHE 543 ASN 544 -0.0001

ASN 544 GLY 545 0.0001

GLY 545 LEU 546 0.0001

LEU 546 THR 547 -0.0000

THR 547 GLY 548 0.0008

GLY 548 THR 549 0.0001

THR 549 GLY 550 0.0002

GLY 550 VAL 551 -0.0002

VAL 551 LEU 552 0.0002

LEU 552 THR 553 -0.0002

THR 553 GLU 554 -0.0004

GLU 554 SER 555 0.0005

SER 555 ASN 556 -0.0001

ASN 556 LYS 557 -0.0004

LYS 557 LYS 558 0.0002

LYS 558 PHE 559 0.0002

PHE 559 LEU 560 -0.0003

LEU 560 PRO 561 0.0002

PRO 561 PHE 562 -0.0001

PHE 562 GLN 563 0.0221

GLN 563 GLN 564 0.0003

GLN 564 PHE 565 0.0001

PHE 565 GLY 566 0.0002

GLY 566 ARG 567 -0.0006

ARG 567 ASP 568 0.0000

ASP 568 ILE 569 0.0001

ILE 569 ALA 570 -0.0001

ALA 570 ASP 571 0.0003

ASP 571 THR 572 -0.0002

THR 572 THR 573 0.0003

THR 573 ASP 574 0.0002

ASP 574 ALA 575 -0.0003

ALA 575 VAL 576 0.0002

VAL 576 ARG 577 -0.0004

ARG 577 ASP 578 -0.0101

ASP 578 PRO 579 -0.0004

PRO 579 GLN 580 0.0002

GLN 580 THR 581 0.0001

THR 581 LEU 582 0.0002

LEU 582 GLU 583 0.0005

GLU 583 ILE 584 -0.0004

ILE 584 LEU 585 -0.0001

LEU 585 ASP 586 0.0000

ASP 586 ILE 587 0.0001

ILE 587 THR 588 -0.0000

THR 588 PRO 589 -0.0003

PRO 589 CYS 590 -0.0001

CYS 590 SER 591 -0.0000

SER 591 PHE 592 0.0003

PHE 592 GLY 593 0.0253

GLY 593 GLY 594 0.0001

GLY 594 VAL 595 -0.0002

VAL 595 SER 596 0.0004

SER 596 VAL 597 0.0000

VAL 597 ILE 598 0.0001

ILE 598 THR 599 0.0002

THR 599 PRO 600 -0.0001

PRO 600 GLY 601 -0.0001

GLY 601 THR 602 0.0002

THR 602 ASN 603 0.0001

ASN 603 THR 604 0.0000

THR 604 SER 605 0.0001

SER 605 ASN 606 0.0003

ASN 606 GLN 607 0.0001

GLN 607 VAL 608 0.0039

VAL 608 ALA 609 -0.0002

ALA 609 VAL 610 0.0000

VAL 610 LEU 611 0.0002

LEU 611 TYR 612 -0.0002

TYR 612 GLN 613 0.0005

GLN 613 ASP 614 -0.0002

ASP 614 VAL 615 -0.0000

VAL 615 ASN 616 0.0004

ASN 616 CYS 617 -0.0002

CYS 617 THR 618 0.0002

THR 618 GLU 619 -0.0002

GLU 619 VAL 620 -0.0001

VAL 620 ASN 641 -0.0021

ASN 641 VAL 642 -0.0000

VAL 642 PHE 643 -0.0001

PHE 643 GLN 644 0.0002

GLN 644 THR 645 0.0001

THR 645 ARG 646 -0.0002

ARG 646 ALA 647 -0.0000

ALA 647 GLY 648 -0.0002

GLY 648 CYS 649 0.0003

CYS 649 LEU 650 -0.0000

LEU 650 ILE 651 -0.0001

ILE 651 GLY 652 -0.0001

GLY 652 ALA 653 -0.0002

ALA 653 GLU 654 0.0001

GLU 654 HIS 655 0.0000

HIS 655 VAL 656 0.0020

VAL 656 ASN 657 0.0003

ASN 657 ASN 658 -0.0000

ASN 658 SER 659 -0.0003

SER 659 TYR 660 -0.0002

TYR 660 GLU 661 0.0002

GLU 661 CYS 662 0.0002

CYS 662 ASP 663 -0.0000

ASP 663 ILE 664 0.0000

ILE 664 PRO 665 -0.0000

PRO 665 ILE 666 -0.0003

ILE 666 GLY 667 0.0003

GLY 667 ALA 668 0.0003

ALA 668 GLY 669 -0.0000

GLY 669 ILE 670 -0.0001

ILE 670 CYS 671 -0.0011

CYS 671 ALA 672 0.0000

ALA 672 SER 673 -0.0001

SER 673 TYR 674 -0.0001

TYR 674 GLN 675 0.0002

GLN 675 THR 676 -0.0001

THR 676 SER 689 0.0020

SER 689 GLN 690 0.0002

GLN 690 SER 691 -0.0005

SER 691 ILE 692 0.0004

ILE 692 ILE 693 -0.0002

ILE 693 ALA 694 0.0004

ALA 694 TYR 695 -0.0002

TYR 695 THR 696 0.0000

THR 696 MET 697 -0.0002

MET 697 SER 698 0.0001

SER 698 LEU 699 -0.0002

LEU 699 GLY 700 0.0006

GLY 700 ALA 701 -0.0002

ALA 701 GLU 702 0.0001

GLU 702 ASN 703 0.0003

ASN 703 SER 704 -0.0341

SER 704 VAL 705 -0.0000

VAL 705 ALA 706 0.0001

ALA 706 TYR 707 -0.0000

TYR 707 SER 708 -0.0004

SER 708 ASN 709 -0.0000

ASN 709 ASN 710 0.0000

ASN 710 SER 711 -0.0002

SER 711 ILE 712 -0.0000

ILE 712 ALA 713 -0.0002

ALA 713 ILE 714 -0.0002

ILE 714 PRO 715 0.0001

PRO 715 THR 716 -0.0000

THR 716 ASN 717 -0.0002

ASN 717 PHE 718 0.0004

PHE 718 THR 719 0.0024

THR 719 ILE 720 0.0001

ILE 720 SER 721 0.0000

SER 721 VAL 722 -0.0002

VAL 722 THR 723 0.0002

THR 723 THR 724 -0.0005

THR 724 GLU 725 -0.0002

GLU 725 ILE 726 0.0000

ILE 726 LEU 727 0.0002

LEU 727 PRO 728 -0.0002

PRO 728 VAL 729 0.0001

VAL 729 SER 730 -0.0003

SER 730 MET 731 0.0002

MET 731 THR 732 0.0000

THR 732 LYS 733 -0.0002

LYS 733 THR 734 -0.0340

THR 734 SER 735 -0.0000

SER 735 VAL 736 0.0001

VAL 736 ASP 737 -0.0005

ASP 737 CYS 738 0.0002

CYS 738 THR 739 0.0001

THR 739 MET 740 -0.0000

MET 740 TYR 741 0.0001

TYR 741 ILE 742 -0.0000

ILE 742 CYS 743 -0.0002

CYS 743 GLY 744 0.0002

GLY 744 ASP 745 0.0001

ASP 745 SER 746 -0.0003

SER 746 THR 747 -0.0004

THR 747 GLU 748 0.0001

GLU 748 CYS 749 0.0041

CYS 749 SER 750 0.0000

SER 750 ASN 751 0.0002

ASN 751 LEU 752 0.0000

LEU 752 LEU 753 -0.0004

LEU 753 LEU 754 -0.0001

LEU 754 GLN 755 0.0003

GLN 755 TYR 756 -0.0001

TYR 756 GLY 757 -0.0005

GLY 757 SER 758 0.0000

SER 758 PHE 759 0.0003

PHE 759 CYS 760 0.0005

CYS 760 THR 761 0.0000

THR 761 GLN 762 0.0002

GLN 762 LEU 763 0.0001

LEU 763 ASN 764 -0.0120

ASN 764 ARG 765 0.0004

ARG 765 ALA 766 -0.0000

ALA 766 LEU 767 -0.0003

LEU 767 THR 768 0.0004

THR 768 GLY 769 -0.0000

GLY 769 ILE 770 -0.0001

ILE 770 ALA 771 -0.0002

ALA 771 VAL 772 -0.0003

VAL 772 GLU 773 0.0001

GLU 773 GLN 774 -0.0003

GLN 774 ASP 775 0.0000

ASP 775 LYS 776 0.0000

LYS 776 ASN 777 0.0002

ASN 777 THR 778 -0.0000

THR 778 GLN 779 -0.0046

GLN 779 GLU 780 0.0002

GLU 780 VAL 781 -0.0002

VAL 781 PHE 782 0.0001

PHE 782 ALA 783 -0.0001

ALA 783 GLN 784 -0.0004

GLN 784 VAL 785 -0.0002

VAL 785 LYS 786 0.0002

LYS 786 GLN 787 0.0002

GLN 787 ILE 788 0.0001

ILE 788 TYR 789 -0.0004

TYR 789 LYS 790 -0.0000

LYS 790 THR 791 -0.0003

THR 791 PRO 792 0.0002

PRO 792 PRO 793 -0.0002

PRO 793 ILE 794 0.0099

ILE 794 LYS 795 -0.0001

LYS 795 ASP 796 0.0002

ASP 796 PHE 797 -0.0002

PHE 797 GLY 798 -0.0002

GLY 798 GLY 799 0.0003

GLY 799 PHE 800 -0.0002

PHE 800 ASN 801 -0.0001

ASN 801 PHE 802 -0.0002

PHE 802 SER 803 0.0001

SER 803 GLN 804 0.0003

GLN 804 ILE 805 0.0001

ILE 805 LEU 806 -0.0003

LEU 806 PRO 807 0.0002

PRO 807 ASP 808 -0.0000

ASP 808 PRO 809 0.0037

PRO 809 SER 810 -0.0003

SER 810 LYS 811 0.0004

LYS 811 PRO 812 -0.0005

PRO 812 SER 813 -0.0003

SER 813 LYS 814 -0.0001

LYS 814 ARG 815 0.0001

ARG 815 SER 816 0.0003

SER 816 PHE 817 0.0001

PHE 817 ILE 818 -0.0002

ILE 818 GLU 819 -0.0000

GLU 819 ASP 820 -0.0001

ASP 820 LEU 821 -0.0006

LEU 821 LEU 822 0.0000

LEU 822 PHE 823 -0.0003

PHE 823 ASN 824 0.0043

ASN 824 LYS 825 0.0001

LYS 825 VAL 826 0.0001

VAL 826 THR 827 0.0000

THR 827 LYS 854 -0.0087

LYS 854 PHE 855 -0.0005

PHE 855 ASN 856 0.0002

ASN 856 GLY 857 -0.0005

GLY 857 LEU 858 0.0002

LEU 858 THR 859 0.0000

THR 859 VAL 860 -0.0002

VAL 860 LEU 861 0.0003

LEU 861 PRO 862 0.0000

PRO 862 PRO 863 0.0002

PRO 863 LEU 864 0.0003

LEU 864 LEU 865 -0.0005

LEU 865 THR 866 0.0003

THR 866 ASP 867 -0.0005

ASP 867 GLU 868 0.0001

GLU 868 MET 869 -0.0261

MET 869 ILE 870 -0.0001

ILE 870 ALA 871 0.0003

ALA 871 GLN 872 0.0004

GLN 872 TYR 873 0.0002

TYR 873 THR 874 0.0002

THR 874 SER 875 -0.0004

SER 875 ALA 876 0.0003

ALA 876 LEU 877 0.0002

LEU 877 LEU 878 0.0004

LEU 878 ALA 879 -0.0002

ALA 879 GLY 880 0.0001

GLY 880 THR 881 -0.0003

THR 881 ILE 882 0.0003

ILE 882 THR 883 0.0001

THR 883 SER 884 -0.0010

SER 884 GLY 885 0.0003

GLY 885 TRP 886 -0.0001

TRP 886 THR 887 0.0002

THR 887 PHE 888 0.0003

PHE 888 GLY 889 0.0001

GLY 889 ALA 890 -0.0001

ALA 890 GLY 891 0.0000

GLY 891 ALA 892 -0.0003

ALA 892 ALA 893 -0.0001

ALA 893 LEU 894 0.0001

LEU 894 GLN 895 0.0000

GLN 895 ILE 896 -0.0002

ILE 896 PRO 897 -0.0002

PRO 897 PHE 898 0.0001

PHE 898 ALA 899 -0.0051

ALA 899 MET 900 -0.0003

MET 900 GLN 901 0.0001

GLN 901 MET 902 0.0001

MET 902 ALA 903 0.0002

ALA 903 TYR 904 -0.0000

TYR 904 ARG 905 0.0005

ARG 905 PHE 906 -0.0002

PHE 906 ASN 907 0.0001

ASN 907 GLY 908 -0.0004

GLY 908 ILE 909 -0.0001

ILE 909 GLY 910 0.0005

GLY 910 VAL 911 -0.0001

VAL 911 THR 912 -0.0002

THR 912 GLN 913 -0.0001

GLN 913 ASN 914 -0.0007

ASN 914 VAL 915 0.0002

VAL 915 LEU 916 -0.0000

LEU 916 TYR 917 0.0000

TYR 917 GLU 918 0.0005

GLU 918 ASN 919 0.0001

ASN 919 GLN 920 0.0000

GLN 920 LYS 921 -0.0000

LYS 921 LEU 922 0.0002

LEU 922 ILE 923 0.0000

ILE 923 ALA 924 0.0000

ALA 924 ASN 925 0.0001

ASN 925 GLN 926 0.0005

GLN 926 PHE 927 -0.0003

PHE 927 ASN 928 -0.0000

ASN 928 SER 929 -0.0093

SER 929 ALA 930 -0.0000

ALA 930 ILE 931 -0.0001

ILE 931 GLY 932 -0.0002

GLY 932 LYS 933 0.0002

LYS 933 ILE 934 0.0004

ILE 934 GLN 935 -0.0001

GLN 935 ASP 936 0.0003

ASP 936 SER 937 -0.0003

SER 937 LEU 938 -0.0001

LEU 938 SER 939 -0.0001

SER 939 SER 940 0.0002

SER 940 THR 941 0.0001

THR 941 ALA 942 0.0001

ALA 942 SER 943 0.0001

SER 943 ALA 944 0.0257

ALA 944 LEU 945 -0.0004

LEU 945 GLY 946 0.0002

GLY 946 LYS 947 0.0004

LYS 947 LEU 948 -0.0001

LEU 948 GLN 949 0.0000

GLN 949 ASP 950 0.0001

ASP 950 VAL 951 0.0002

VAL 951 VAL 952 -0.0001

VAL 952 ASN 953 -0.0001

ASN 953 GLN 954 -0.0003

GLN 954 ASN 955 0.0002

ASN 955 ALA 956 0.0001

ALA 956 GLN 957 -0.0004

GLN 957 ALA 958 -0.0000

ALA 958 LEU 959 -0.0035

LEU 959 ASN 960 -0.0001

ASN 960 THR 961 -0.0001

THR 961 LEU 962 -0.0002

LEU 962 VAL 963 -0.0003

VAL 963 LYS 964 0.0000

LYS 964 GLN 965 0.0000

GLN 965 LEU 966 -0.0002

LEU 966 SER 967 -0.0001

SER 967 SER 968 0.0003

SER 968 ASN 969 0.0002

ASN 969 PHE 970 0.0000

PHE 970 GLY 971 0.0002

GLY 971 ALA 972 0.0001

ALA 972 ILE 973 -0.0001

ILE 973 SER 974 0.0376

SER 974 SER 975 0.0000

SER 975 VAL 976 -0.0001

VAL 976 LEU 977 -0.0003

LEU 977 ASN 978 -0.0001

ASN 978 ASP 979 -0.0002

ASP 979 ILE 980 0.0000

ILE 980 LEU 981 0.0000

LEU 981 SER 982 -0.0000

SER 982 ARG 983 -0.0000

ARG 983 LEU 984 0.0000

LEU 984 ASP 985 -0.0001

ASP 985 PRO 986 -0.0004

PRO 986 PRO 987 -0.0002

PRO 987 GLU 988 0.0003

GLU 988 ALA 989 -0.0105

ALA 989 GLU 990 0.0000

GLU 990 VAL 991 -0.0001

VAL 991 GLN 992 0.0003

GLN 992 ILE 993 -0.0002

ILE 993 ASP 994 -0.0000

ASP 994 ARG 995 -0.0001

ARG 995 LEU 996 -0.0003

LEU 996 ILE 997 0.0003

ILE 997 THR 998 0.0002

THR 998 GLY 999 -0.0000

GLY 999 ARG 1000 -0.0001

ARG 1000 LEU 1001 -0.0000

LEU 1001 GLN 1002 -0.0001

GLN 1002 SER 1003 -0.0001

SER 1003 LEU 1004 -0.0001

LEU 1004 GLN 1005 0.0001

GLN 1005 THR 1006 0.0004

THR 1006 TYR 1007 -0.0002

TYR 1007 VAL 1008 -0.0003

VAL 1008 THR 1009 0.0002

THR 1009 GLN 1010 0.0003

GLN 1010 GLN 1011 0.0001

GLN 1011 LEU 1012 0.0001

LEU 1012 ILE 1013 -0.0001

ILE 1013 ARG 1014 -0.0001

ARG 1014 ALA 1015 0.0001

ALA 1015 ALA 1016 0.0002

ALA 1016 GLU 1017 0.0001

GLU 1017 ILE 1018 -0.0001

ILE 1018 ARG 1019 -0.0115

ARG 1019 ALA 1020 0.0001

ALA 1020 SER 1021 0.0002

SER 1021 ALA 1022 0.0003

ALA 1022 ASN 1023 -0.0002

ASN 1023 LEU 1024 0.0003

LEU 1024 ALA 1025 -0.0001

ALA 1025 ALA 1026 -0.0002

ALA 1026 THR 1027 0.0001

THR 1027 LYS 1028 -0.0002

LYS 1028 MET 1029 0.0001

MET 1029 SER 1030 0.0001

SER 1030 GLU 1031 -0.0001

GLU 1031 CYS 1032 0.0000

CYS 1032 VAL 1033 -0.0000

VAL 1033 LEU 1034 -0.0027

LEU 1034 GLY 1035 0.0000

GLY 1035 GLN 1036 -0.0001

GLN 1036 SER 1037 0.0002

SER 1037 LYS 1038 -0.0002

LYS 1038 ARG 1039 -0.0001

ARG 1039 VAL 1040 0.0002

VAL 1040 ASP 1041 0.0000

ASP 1041 PHE 1042 0.0002

PHE 1042 CYS 1043 -0.0001

CYS 1043 GLY 1044 0.0001

GLY 1044 LYS 1045 -0.0001

LYS 1045 GLY 1046 -0.0002

GLY 1046 TYR 1047 0.0000

TYR 1047 HIS 1048 0.0001

HIS 1048 LEU 1049 0.0050

LEU 1049 MET 1050 0.0001

MET 1050 SER 1051 -0.0004

SER 1051 PHE 1052 0.0001

PHE 1052 PRO 1053 0.0001

PRO 1053 GLN 1054 0.0002

GLN 1054 SER 1055 0.0001

SER 1055 ALA 1056 0.0002

ALA 1056 PRO 1057 0.0003

PRO 1057 HIS 1058 -0.0001

HIS 1058 GLY 1059 -0.0001

GLY 1059 VAL 1060 0.0003

VAL 1060 VAL 1061 -0.0000

VAL 1061 PHE 1062 0.0003

PHE 1062 LEU 1063 -0.0001

LEU 1063 HIS 1064 0.0009

HIS 1064 VAL 1065 0.0000

VAL 1065 THR 1066 0.0001

THR 1066 TYR 1067 -0.0000

TYR 1067 VAL 1068 0.0003

VAL 1068 PRO 1069 -0.0001

PRO 1069 ALA 1070 -0.0001

ALA 1070 GLN 1071 0.0003

GLN 1071 GLU 1072 -0.0004

GLU 1072 LYS 1073 -0.0000

LYS 1073 ASN 1074 0.0002

ASN 1074 PHE 1075 -0.0001

PHE 1075 THR 1076 0.0002

THR 1076 THR 1077 -0.0001

THR 1077 ALA 1078 -0.0005

ALA 1078 PRO 1079 0.0045

PRO 1079 ALA 1080 0.0002

ALA 1080 ILE 1081 0.0004

ILE 1081 CYS 1082 -0.0003

CYS 1082 HIS 1083 0.0001

HIS 1083 ASP 1084 0.0001

ASP 1084 GLY 1085 -0.0002

GLY 1085 LYS 1086 0.0004

LYS 1086 ALA 1087 -0.0000

ALA 1087 HIS 1088 -0.0003

HIS 1088 PHE 1089 0.0004

PHE 1089 PRO 1090 -0.0005

PRO 1090 ARG 1091 -0.0001

ARG 1091 GLU 1092 0.0001

GLU 1092 GLY 1093 -0.0001

GLY 1093 VAL 1094 0.0034

VAL 1094 PHE 1095 -0.0001

PHE 1095 VAL 1096 -0.0000

VAL 1096 SER 1097 0.0003

SER 1097 ASN 1098 -0.0003

ASN 1098 GLY 1099 -0.0002

GLY 1099 THR 1100 -0.0005

THR 1100 HIS 1101 -0.0002

HIS 1101 TRP 1102 -0.0002

TRP 1102 PHE 1103 0.0001

PHE 1103 VAL 1104 -0.0002

VAL 1104 THR 1105 0.0000

THR 1105 GLN 1106 -0.0002

GLN 1106 ARG 1107 -0.0001

ARG 1107 ASN 1108 0.0000

ASN 1108 PHE 1109 0.0036

PHE 1109 TYR 1110 0.0001

TYR 1110 GLU 1111 0.0002

GLU 1111 PRO 1112 0.0002

PRO 1112 GLN 1113 0.0001

GLN 1113 ILE 1114 -0.0003

ILE 1114 ILE 1115 0.0002

ILE 1115 THR 1116 -0.0001

THR 1116 THR 1117 0.0002

THR 1117 ASP 1118 0.0002

ASP 1118 ASN 1119 -0.0001

ASN 1119 THR 1120 0.0002

THR 1120 PHE 1121 -0.0004

PHE 1121 VAL 1122 -0.0000

VAL 1122 SER 1123 0.0005

SER 1123 GLY 1124 -0.0015

GLY 1124 ASN 1125 0.0003

ASN 1125 CYS 1126 -0.0002

CYS 1126 ASP 1127 -0.0000

ASP 1127 VAL 1128 -0.0001

VAL 1128 VAL 1129 0.0002

VAL 1129 ILE 1130 -0.0002

ILE 1130 GLY 1131 0.0001

GLY 1131 ILE 1132 -0.0001

ILE 1132 VAL 1133 -0.0000

VAL 1133 ASN 1134 0.0003

ASN 1134 ASN 1135 -0.0001

ASN 1135 THR 1136 -0.0000

THR 1136 VAL 1137 -0.0000

VAL 1137 TYR 1138 0.0002

TYR 1138 ASP 1139 -0.0003

ASP 1139 PRO 1140 -0.0004

PRO 1140 LEU 1141 0.0003

LEU 1141 GLN 1142 0.0000

GLN 1142 PRO 1143 -0.0000

PRO 1143 GLU 1144 0.0004

GLU 1144 LEU 1145 -0.0004

LEU 1145 ASP 1146 -0.0001

ASP 1146 SER 1147 -0.0001

SER 1147 ALA 27 0.0160

ALA 27 TYR 28 0.0001

TYR 28 THR 29 0.0000

THR 29 ASN 30 -0.0001

ASN 30 SER 31 -0.0003

SER 31 PHE 32 -0.0000

PHE 32 THR 33 -0.0003

THR 33 ARG 34 0.0001

ARG 34 GLY 35 -0.0001

GLY 35 VAL 36 0.0001

VAL 36 TYR 37 -0.0002

TYR 37 TYR 38 -0.0002

TYR 38 PRO 39 0.0002

PRO 39 ASP 40 0.0003

ASP 40 LYS 41 0.0000

LYS 41 VAL 42 0.0439

VAL 42 PHE 43 -0.0002

PHE 43 ARG 44 0.0000

ARG 44 SER 45 -0.0001

SER 45 SER 46 0.0002

SER 46 VAL 47 -0.0001

VAL 47 LEU 48 -0.0003

LEU 48 HIS 49 0.0002

HIS 49 SER 50 -0.0002

SER 50 THR 51 -0.0001

THR 51 GLN 52 0.0005

GLN 52 ASP 53 -0.0002

ASP 53 LEU 54 -0.0001

LEU 54 PHE 55 -0.0001

PHE 55 LEU 56 0.0002

LEU 56 PRO 57 0.0163

PRO 57 PHE 58 0.0001

PHE 58 PHE 59 -0.0002

PHE 59 SER 60 0.0002

SER 60 ASN 61 -0.0001

ASN 61 VAL 62 0.0001

VAL 62 THR 63 -0.0005

THR 63 TRP 64 0.0003

TRP 64 PHE 65 0.0001

PHE 65 HIS 66 -0.0000

HIS 66 ALA 67 0.0003

ALA 67 ILE 68 -0.0002

ILE 68 HIS 69 0.0000

HIS 69 ASP 80 -0.0003

ASP 80 ASN 81 -0.0002

ASN 81 PRO 82 -0.0004

PRO 82 VAL 83 0.0001

VAL 83 LEU 84 0.0002

LEU 84 PRO 85 -0.0004

PRO 85 PHE 86 -0.0002

PHE 86 ASN 87 -0.0003

ASN 87 ASP 88 -0.0001

ASP 88 GLY 89 -0.0004

GLY 89 VAL 90 0.0002

VAL 90 TYR 91 0.0001

TYR 91 PHE 92 0.0002

PHE 92 ALA 93 0.0000

ALA 93 SER 94 -0.0001

SER 94 THR 95 0.0011

THR 95 GLU 96 0.0002

GLU 96 LYS 97 -0.0005

LYS 97 SER 98 -0.0003

SER 98 ASN 99 -0.0002

ASN 99 ILE 100 0.0000

ILE 100 ILE 101 -0.0002

ILE 101 ARG 102 0.0004

ARG 102 GLY 103 -0.0000

GLY 103 TRP 104 0.0001

TRP 104 ILE 105 -0.0001

ILE 105 PHE 106 0.0004

PHE 106 GLY 107 -0.0003

GLY 107 THR 108 -0.0001

THR 108 THR 109 0.0001

THR 109 LEU 110 -0.0031

LEU 110 ASP 111 -0.0003

ASP 111 SER 112 0.0002

SER 112 LYS 113 -0.0003

LYS 113 THR 114 -0.0002

THR 114 GLN 115 0.0004

GLN 115 SER 116 -0.0004

SER 116 LEU 117 0.0001

LEU 117 LEU 118 0.0000

LEU 118 ILE 119 -0.0000

ILE 119 VAL 120 0.0002

VAL 120 ASN 121 -0.0001

ASN 121 ASN 122 0.0002

ASN 122 ALA 123 0.0002

ALA 123 THR 124 -0.0000

THR 124 ASN 125 -0.0003

ASN 125 VAL 126 0.0001

VAL 126 VAL 127 -0.0000

VAL 127 ILE 128 -0.0000

ILE 128 LYS 129 0.0002

LYS 129 VAL 130 -0.0002

VAL 130 CYS 131 -0.0000

CYS 131 GLU 132 -0.0001

GLU 132 PHE 133 0.0000

PHE 133 GLN 134 -0.0001

GLN 134 PHE 135 -0.0001

PHE 135 CYS 136 -0.0001

CYS 136 ASN 137 0.0003

ASN 137 ASP 138 -0.0001

ASP 138 PRO 139 0.0001

PRO 139 PHE 140 0.0038

PHE 140 LEU 141 0.0002

LEU 141 GLY 142 0.0002

GLY 142 VAL 143 -0.0001

VAL 143 ASN 165 -0.0004

ASN 165 CYS 166 -0.0001

CYS 166 THR 167 0.0002

THR 167 PHE 168 0.0000

PHE 168 GLU 169 -0.0001

GLU 169 TYR 170 0.0003

TYR 170 VAL 171 0.0001

VAL 171 SER 172 0.0000

SER 172 PHE 186 -0.0010

PHE 186 LYS 187 0.0002

LYS 187 ASN 188 -0.0000

ASN 188 LEU 189 -0.0001

LEU 189 ARG 190 0.0001

ARG 190 GLU 191 0.0001

GLU 191 PHE 192 -0.0003

PHE 192 VAL 193 0.0000

VAL 193 PHE 194 -0.0003

PHE 194 LYS 195 0.0002

LYS 195 ASN 196 0.0001

ASN 196 ILE 197 0.0002

ILE 197 ASP 198 -0.0000

ASP 198 GLY 199 0.0003

GLY 199 TYR 200 -0.0003

TYR 200 PHE 201 -0.0068

PHE 201 LYS 202 -0.0004

LYS 202 ILE 203 -0.0001

ILE 203 TYR 204 0.0004

TYR 204 SER 205 -0.0002

SER 205 LYS 206 -0.0000

LYS 206 HIS 207 0.0000

HIS 207 THR 208 -0.0002

THR 208 PRO 209 0.0004

PRO 209 ILE 210 -0.0001

ILE 210 ASN 211 -0.0001

ASN 211 LEU 212 -0.0002

LEU 212 VAL 213 0.0000

VAL 213 ARG 214 -0.0002

ARG 214 ASP 215 0.0000

ASP 215 LEU 216 0.0172

LEU 216 PRO 217 0.0001

PRO 217 GLN 218 -0.0003

GLN 218 GLY 219 -0.0001

GLY 219 PHE 220 -0.0002

PHE 220 SER 221 0.0001

SER 221 ALA 222 -0.0002

ALA 222 LEU 223 -0.0002

LEU 223 GLU 224 0.0003

GLU 224 PRO 225 -0.0000

PRO 225 LEU 226 -0.0001

LEU 226 VAL 227 -0.0003

VAL 227 ASP 228 0.0002

ASP 228 LEU 229 -0.0002

LEU 229 PRO 230 0.0000

PRO 230 ILE 231 0.0231

ILE 231 GLY 232 -0.0004

GLY 232 ILE 233 0.0000

ILE 233 ASN 234 -0.0002

ASN 234 ILE 235 -0.0002

ILE 235 THR 236 0.0000

THR 236 ARG 237 -0.0004

ARG 237 PHE 238 0.0002

PHE 238 GLN 239 0.0002

GLN 239 THR 240 -0.0001

THR 240 LEU 241 0.0000

LEU 241 LEU 242 -0.0001

LEU 242 ALA 243 0.0000

ALA 243 LEU 244 -0.0002

LEU 244 HIS 245 0.0000

HIS 245 ALA 263 -0.0015

ALA 263 ALA 264 -0.0003

ALA 264 TYR 265 0.0001

TYR 265 TYR 266 -0.0000

TYR 266 VAL 267 -0.0002

VAL 267 GLY 268 -0.0003

GLY 268 TYR 269 -0.0000

TYR 269 LEU 270 0.0001

LEU 270 GLN 271 0.0000

GLN 271 PRO 272 -0.0001

PRO 272 ARG 273 -0.0004

ARG 273 THR 274 0.0002

THR 274 PHE 275 0.0003

PHE 275 LEU 276 0.0001

LEU 276 LEU 277 -0.0002

LEU 277 LYS 278 0.0006

LYS 278 TYR 279 -0.0001

TYR 279 ASN 280 0.0000

ASN 280 GLU 281 0.0003

GLU 281 ASN 282 -0.0002

ASN 282 GLY 283 -0.0000

GLY 283 THR 284 0.0001

THR 284 ILE 285 0.0001

ILE 285 THR 286 -0.0001

THR 286 ASP 287 -0.0002

ASP 287 ALA 288 0.0003

ALA 288 VAL 289 0.0001

VAL 289 ASP 290 -0.0002

ASP 290 CYS 291 -0.0002

CYS 291 ALA 292 0.0002

ALA 292 LEU 293 0.0993

LEU 293 ASP 294 -0.0001

ASP 294 PRO 295 -0.0001

PRO 295 LEU 296 0.0001

LEU 296 SER 297 0.0001

SER 297 GLU 298 -0.0000

GLU 298 THR 299 -0.0002

THR 299 LYS 300 0.0002

LYS 300 CYS 301 0.0002

CYS 301 THR 302 0.0002

THR 302 LEU 303 -0.0003

LEU 303 LYS 304 -0.0001

LYS 304 SER 305 -0.0002

SER 305 PHE 306 0.0002

PHE 306 THR 307 0.0001

THR 307 VAL 308 0.0516

VAL 308 GLU 309 0.0000

GLU 309 LYS 310 -0.0000

LYS 310 GLY 311 0.0001

GLY 311 ILE 312 -0.0005

ILE 312 TYR 313 0.0001

TYR 313 GLN 314 0.0002

GLN 314 THR 315 -0.0005

THR 315 SER 316 0.0001

SER 316 ASN 317 -0.0004

ASN 317 PHE 318 0.0000

PHE 318 ARG 319 -0.0000

ARG 319 VAL 320 0.0001

VAL 320 GLN 321 0.0000

GLN 321 PRO 322 0.0003

PRO 322 THR 323 0.0232

THR 323 GLU 324 -0.0002

GLU 324 SER 325 -0.0001

SER 325 ILE 326 0.0001

ILE 326 VAL 327 -0.0000

VAL 327 ARG 328 0.0001

ARG 328 PHE 329 0.0003

PHE 329 PRO 330 -0.0000

PRO 330 ASN 331 0.0001

ASN 331 ILE 332 -0.0004

ILE 332 THR 333 0.0001

THR 333 ASN 334 0.0001

ASN 334 LEU 335 0.0000

LEU 335 CYS 336 0.0002

CYS 336 PRO 337 -0.0001

PRO 337 PHE 338 -0.0157

PHE 338 GLY 339 -0.0001

GLY 339 GLU 340 0.0000

GLU 340 VAL 341 -0.0004

VAL 341 PHE 342 0.0001

PHE 342 ASN 343 -0.0003

ASN 343 ALA 344 -0.0003

ALA 344 THR 345 0.0005

THR 345 ARG 346 0.0003

ARG 346 PHE 347 -0.0004

PHE 347 ALA 348 0.0001

ALA 348 SER 349 -0.0003

SER 349 VAL 350 0.0004

VAL 350 TYR 351 0.0003

TYR 351 ALA 352 -0.0000

ALA 352 TRP 353 0.0076

TRP 353 ASN 354 -0.0004

ASN 354 ARG 355 0.0001

ARG 355 LYS 356 -0.0001

LYS 356 ARG 357 -0.0002

ARG 357 ILE 358 0.0004

ILE 358 SER 359 0.0003

SER 359 ASN 360 -0.0004

ASN 360 CYS 361 -0.0001

CYS 361 VAL 362 0.0002

VAL 362 ALA 363 -0.0001

ALA 363 ASP 364 -0.0001

ASP 364 TYR 365 0.0001

TYR 365 SER 366 0.0002

SER 366 VAL 367 -0.0001

VAL 367 LEU 368 0.0217

LEU 368 TYR 369 -0.0005

TYR 369 ASN 370 -0.0002

ASN 370 SER 371 0.0000

SER 371 ALA 372 -0.0001

ALA 372 SER 373 -0.0002

SER 373 PHE 374 0.0002

PHE 374 SER 375 0.0001

SER 375 THR 376 -0.0001

THR 376 PHE 377 -0.0001

PHE 377 LYS 378 0.0001

LYS 378 CYS 379 -0.0004

CYS 379 TYR 380 -0.0001

TYR 380 GLY 381 -0.0001

GLY 381 VAL 382 0.0001

VAL 382 SER 383 -0.0033

SER 383 PRO 384 0.0002

PRO 384 THR 385 -0.0002

THR 385 LYS 386 -0.0001

LYS 386 LEU 387 -0.0002

LEU 387 ASN 388 0.0001

ASN 388 ASP 389 0.0002

ASP 389 LEU 390 0.0001

LEU 390 CYS 391 0.0000

CYS 391 PHE 392 -0.0003

PHE 392 THR 393 -0.0000

THR 393 ASN 394 0.0001

ASN 394 VAL 395 -0.0000

VAL 395 TYR 396 -0.0002

TYR 396 ALA 397 0.0001

ALA 397 ASP 398 0.0186

ASP 398 SER 399 0.0001

SER 399 PHE 400 -0.0000

PHE 400 VAL 401 0.0004

VAL 401 ILE 402 -0.0004

ILE 402 ARG 403 -0.0001

ARG 403 GLY 404 -0.0001

GLY 404 ASP 405 -0.0002

ASP 405 GLU 406 0.0001

GLU 406 VAL 407 0.0002

VAL 407 ARG 408 -0.0001

ARG 408 GLN 409 0.0001

GLN 409 ILE 410 -0.0003

ILE 410 ALA 411 0.0004

ALA 411 PRO 412 -0.0001

PRO 412 GLY 413 -0.0078

GLY 413 GLN 414 -0.0002

GLN 414 THR 415 0.0000

THR 415 GLY 416 0.0001

GLY 416 LYS 417 -0.0001

LYS 417 ILE 418 0.0000

ILE 418 ALA 419 -0.0002

ALA 419 ASP 420 0.0003

ASP 420 TYR 421 -0.0001

TYR 421 ASN 422 -0.0001

ASN 422 TYR 423 0.0002

TYR 423 LYS 424 -0.0002

LYS 424 LEU 425 0.0001

LEU 425 PRO 426 0.0001

PRO 426 ASP 427 0.0001

ASP 427 ASP 428 0.0111

ASP 428 PHE 429 0.0002

PHE 429 THR 430 0.0001

THR 430 GLY 431 0.0002

GLY 431 CYS 432 -0.0001

CYS 432 VAL 433 0.0002

VAL 433 ILE 434 0.0003

ILE 434 ALA 435 -0.0002

ALA 435 TRP 436 -0.0001

TRP 436 ASN 437 0.0004

ASN 437 SER 438 -0.0003

SER 438 ASN 439 -0.0001

ASN 439 ASN 440 0.0001

ASN 440 LEU 441 -0.0003

LEU 441 ASP 442 0.0003

ASP 442 SER 443 0.0009

SER 443 LYS 444 -0.0000

LYS 444 GLY 447 -0.0007

GLY 447 ASN 448 0.0003

ASN 448 TYR 449 -0.0000

TYR 449 ASN 450 -0.0003

ASN 450 TYR 451 0.0002

TYR 451 LEU 452 -0.0001

LEU 452 TYR 453 0.0004

TYR 453 ARG 454 -0.0002

ARG 454 LYS 462 -0.0033

LYS 462 PRO 463 0.0002

PRO 463 PHE 464 -0.0005

PHE 464 GLU 465 -0.0002

GLU 465 ARG 466 -0.0000

ARG 466 ASP 467 -0.0001

ASP 467 ILE 468 -0.0002

ILE 468 TYR 489 0.0032

TYR 489 PHE 490 -0.0000

PHE 490 PRO 491 -0.0003

PRO 491 LEU 492 0.0001

LEU 492 GLN 493 -0.0001

GLN 493 SER 494 -0.0001

SER 494 TYR 495 -0.0002

TYR 495 GLY 496 0.0005

GLY 496 PHE 497 0.0001

PHE 497 GLN 498 0.0002

GLN 498 PRO 499 -0.0002

PRO 499 THR 500 -0.0001

THR 500 ASN 501 -0.0001

ASN 501 VAL 503 0.0029

VAL 503 GLY 504 -0.0002

GLY 504 TYR 505 -0.0000

TYR 505 GLN 506 0.0001

GLN 506 PRO 507 0.0001

PRO 507 TYR 508 -0.0001

TYR 508 ARG 509 0.0003

ARG 509 VAL 510 0.0001

VAL 510 VAL 511 -0.0001

VAL 511 VAL 512 -0.0002

VAL 512 LEU 513 -0.0000

LEU 513 SER 514 -0.0003

SER 514 PHE 515 0.0002

PHE 515 GLU 516 0.0001

GLU 516 LEU 517 0.0002

LEU 517 LEU 518 0.0062

LEU 518 HIS 519 0.0003

HIS 519 ALA 520 0.0002

ALA 520 PRO 521 -0.0002

PRO 521 ALA 522 0.0003

ALA 522 THR 523 -0.0000

THR 523 VAL 524 -0.0003

VAL 524 CYS 525 -0.0001

CYS 525 GLY 526 -0.0001

GLY 526 PRO 527 -0.0002

PRO 527 LYS 528 -0.0002

LYS 528 LYS 529 -0.0000

LYS 529 SER 530 -0.0000

SER 530 THR 531 0.0002

THR 531 ASN 532 0.0000

ASN 532 LEU 533 0.0099

LEU 533 VAL 534 0.0003

VAL 534 LYS 535 -0.0001

LYS 535 ASN 536 -0.0000

ASN 536 LYS 537 0.0004

LYS 537 CYS 538 0.0004

CYS 538 VAL 539 -0.0000

VAL 539 ASN 540 -0.0001

ASN 540 PHE 541 -0.0001

PHE 541 ASN 542 0.0003

ASN 542 PHE 543 -0.0002

PHE 543 ASN 544 -0.0000

ASN 544 GLY 545 0.0001

GLY 545 LEU 546 -0.0002

LEU 546 THR 547 -0.0003

THR 547 GLY 548 0.0129

GLY 548 THR 549 0.0003

THR 549 GLY 550 0.0003

GLY 550 VAL 551 -0.0003

VAL 551 LEU 552 -0.0002

LEU 552 THR 553 0.0002

THR 553 GLU 554 -0.0003

GLU 554 SER 555 -0.0000

SER 555 ASN 556 -0.0002

ASN 556 LYS 557 0.0003

LYS 557 LYS 558 -0.0002

LYS 558 PHE 559 0.0002

PHE 559 LEU 560 0.0001

LEU 560 PRO 561 -0.0003

PRO 561 PHE 562 -0.0000

PHE 562 GLN 563 -0.0007

GLN 563 GLN 564 0.0004

GLN 564 PHE 565 0.0000

PHE 565 GLY 566 0.0002

GLY 566 ARG 567 -0.0001

ARG 567 ASP 568 0.0001

ASP 568 ILE 569 -0.0001

ILE 569 ALA 570 0.0002

ALA 570 ASP 571 -0.0001

ASP 571 THR 572 0.0001

THR 572 THR 573 -0.0001

THR 573 ASP 574 0.0001

ASP 574 ALA 575 0.0000

ALA 575 VAL 576 -0.0000

VAL 576 ARG 577 0.0000

ARG 577 ASP 578 0.0009

ASP 578 PRO 579 -0.0002

PRO 579 GLN 580 0.0002

GLN 580 THR 581 -0.0002

THR 581 LEU 582 -0.0002

LEU 582 GLU 583 -0.0000

GLU 583 ILE 584 0.0001

ILE 584 LEU 585 0.0003

LEU 585 ASP 586 -0.0002

ASP 586 ILE 587 -0.0002

ILE 587 THR 588 0.0001

THR 588 PRO 589 0.0000

PRO 589 CYS 590 -0.0002

CYS 590 SER 591 0.0002

SER 591 PHE 592 0.0002

PHE 592 GLY 593 0.0050

GLY 593 GLY 594 0.0001

GLY 594 VAL 595 -0.0001

VAL 595 SER 596 0.0002

SER 596 VAL 597 0.0003

VAL 597 ILE 598 -0.0001

ILE 598 THR 599 0.0000

THR 599 PRO 600 0.0001

PRO 600 GLY 601 0.0001

GLY 601 THR 602 -0.0001

THR 602 ASN 603 -0.0000

ASN 603 THR 604 0.0002

THR 604 SER 605 -0.0002

SER 605 ASN 606 -0.0001

ASN 606 GLN 607 -0.0002

GLN 607 VAL 608 -0.0077

VAL 608 ALA 609 -0.0001

ALA 609 VAL 610 0.0001

VAL 610 LEU 611 -0.0001

LEU 611 TYR 612 -0.0003

TYR 612 GLN 613 -0.0002

GLN 613 ASP 614 0.0002

ASP 614 VAL 615 -0.0000

VAL 615 ASN 616 0.0002

ASN 616 CYS 617 0.0001

CYS 617 THR 618 0.0004

THR 618 GLU 619 -0.0003

GLU 619 VAL 620 -0.0003

VAL 620 ASN 641 0.0065

ASN 641 VAL 642 -0.0005

VAL 642 PHE 643 0.0006

PHE 643 GLN 644 -0.0001

GLN 644 THR 645 -0.0001

THR 645 ARG 646 0.0002

ARG 646 ALA 647 0.0002

ALA 647 GLY 648 0.0002

GLY 648 CYS 649 -0.0005

CYS 649 LEU 650 0.0003

LEU 650 ILE 651 0.0001

ILE 651 GLY 652 -0.0001

GLY 652 ALA 653 0.0002

ALA 653 GLU 654 0.0002

GLU 654 HIS 655 0.0000

HIS 655 VAL 656 0.0131

VAL 656 ASN 657 0.0002

ASN 657 ASN 658 -0.0001

ASN 658 SER 659 -0.0000

SER 659 TYR 660 -0.0000

TYR 660 GLU 661 0.0002

GLU 661 CYS 662 0.0001

CYS 662 ASP 663 -0.0003

ASP 663 ILE 664 0.0000

ILE 664 PRO 665 0.0003

PRO 665 ILE 666 -0.0003

ILE 666 GLY 667 0.0002

GLY 667 ALA 668 0.0001

ALA 668 GLY 669 0.0003

GLY 669 ILE 670 0.0001

ILE 670 CYS 671 -0.0031

CYS 671 ALA 672 0.0001

ALA 672 SER 673 0.0003

SER 673 TYR 674 -0.0004

TYR 674 GLN 675 0.0001

GLN 675 THR 676 0.0002

THR 676 SER 689 -0.0029

SER 689 GLN 690 -0.0001

GLN 690 SER 691 0.0002

SER 691 ILE 692 0.0004

ILE 692 ILE 693 0.0002

ILE 693 ALA 694 -0.0002

ALA 694 TYR 695 0.0004

TYR 695 THR 696 0.0001

THR 696 MET 697 -0.0001

MET 697 SER 698 0.0000

SER 698 LEU 699 0.0001

LEU 699 GLY 700 -0.0003

GLY 700 ALA 701 -0.0001

ALA 701 GLU 702 -0.0002

GLU 702 ASN 703 -0.0003

ASN 703 SER 704 0.0371

SER 704 VAL 705 0.0000

VAL 705 ALA 706 0.0002

ALA 706 TYR 707 -0.0000

TYR 707 SER 708 -0.0002

SER 708 ASN 709 0.0002

ASN 709 ASN 710 -0.0000

ASN 710 SER 711 -0.0001

SER 711 ILE 712 -0.0000

ILE 712 ALA 713 -0.0001

ALA 713 ILE 714 0.0001

ILE 714 PRO 715 0.0001

PRO 715 THR 716 0.0000

THR 716 ASN 717 -0.0001

ASN 717 PHE 718 -0.0000

PHE 718 THR 719 -0.0077

THR 719 ILE 720 0.0003

ILE 720 SER 721 -0.0000

SER 721 VAL 722 -0.0001

VAL 722 THR 723 0.0003

THR 723 THR 724 0.0001

THR 724 GLU 725 -0.0004

GLU 725 ILE 726 0.0003

ILE 726 LEU 727 -0.0003

LEU 727 PRO 728 0.0001

PRO 728 VAL 729 0.0001

VAL 729 SER 730 -0.0001

SER 730 MET 731 -0.0001

MET 731 THR 732 0.0001

THR 732 LYS 733 -0.0003

LYS 733 THR 734 0.0040

THR 734 SER 735 -0.0000

SER 735 VAL 736 -0.0001

VAL 736 ASP 737 0.0000

ASP 737 CYS 738 0.0001

CYS 738 THR 739 0.0001

THR 739 MET 740 -0.0004

MET 740 TYR 741 0.0002

TYR 741 ILE 742 -0.0001

ILE 742 CYS 743 0.0002

CYS 743 GLY 744 0.0003

GLY 744 ASP 745 0.0000

ASP 745 SER 746 0.0001

SER 746 THR 747 -0.0002

THR 747 GLU 748 -0.0004

GLU 748 CYS 749 -0.0089

CYS 749 SER 750 -0.0001

SER 750 ASN 751 0.0001

ASN 751 LEU 752 -0.0001

LEU 752 LEU 753 0.0002

LEU 753 LEU 754 -0.0001

LEU 754 GLN 755 0.0002

GLN 755 TYR 756 0.0001

TYR 756 GLY 757 0.0003

GLY 757 SER 758 -0.0000

SER 758 PHE 759 -0.0002

PHE 759 CYS 760 -0.0000

CYS 760 THR 761 0.0003

THR 761 GLN 762 0.0003

GLN 762 LEU 763 0.0001

LEU 763 ASN 764 0.0122

ASN 764 ARG 765 0.0002

ARG 765 ALA 766 -0.0001

ALA 766 LEU 767 0.0003

LEU 767 THR 768 0.0004

THR 768 GLY 769 0.0001

GLY 769 ILE 770 0.0004

ILE 770 ALA 771 0.0003

ALA 771 VAL 772 -0.0002

VAL 772 GLU 773 -0.0001

GLU 773 GLN 774 -0.0000

GLN 774 ASP 775 0.0001

ASP 775 LYS 776 -0.0000

LYS 776 ASN 777 -0.0003

ASN 777 THR 778 -0.0004

THR 778 GLN 779 0.0079

GLN 779 GLU 780 -0.0002

GLU 780 VAL 781 -0.0000

VAL 781 PHE 782 0.0000

PHE 782 ALA 783 0.0002

ALA 783 GLN 784 -0.0001

GLN 784 VAL 785 0.0001

VAL 785 LYS 786 0.0001

LYS 786 GLN 787 0.0001

GLN 787 ILE 788 0.0001

ILE 788 TYR 789 0.0002

TYR 789 LYS 790 0.0001

LYS 790 THR 791 -0.0005

THR 791 PRO 792 0.0001

PRO 792 PRO 793 -0.0003

PRO 793 ILE 794 -0.0127

ILE 794 LYS 795 0.0000

LYS 795 ASP 796 -0.0000

ASP 796 PHE 797 -0.0004

PHE 797 GLY 798 0.0003

GLY 798 GLY 799 -0.0003

GLY 799 PHE 800 0.0002

PHE 800 ASN 801 -0.0000

ASN 801 PHE 802 0.0003

PHE 802 SER 803 -0.0001

SER 803 GLN 804 -0.0002

GLN 804 ILE 805 0.0001

ILE 805 LEU 806 -0.0002

LEU 806 PRO 807 0.0001

PRO 807 ASP 808 -0.0003

ASP 808 PRO 809 -0.0046

PRO 809 SER 810 -0.0003

SER 810 LYS 811 0.0001

LYS 811 PRO 812 0.0001

PRO 812 SER 813 0.0002

SER 813 LYS 814 0.0001

LYS 814 ARG 815 -0.0003

ARG 815 SER 816 -0.0001

SER 816 PHE 817 0.0000

PHE 817 ILE 818 -0.0005

ILE 818 GLU 819 -0.0001

GLU 819 ASP 820 0.0001

ASP 820 LEU 821 0.0004

LEU 821 LEU 822 0.0001

LEU 822 PHE 823 0.0001

PHE 823 ASN 824 -0.0054

ASN 824 LYS 825 -0.0000

LYS 825 VAL 826 0.0001

VAL 826 THR 827 -0.0004

THR 827 LYS 854 0.0032

LYS 854 PHE 855 0.0001

PHE 855 ASN 856 0.0000

ASN 856 GLY 857 -0.0000

GLY 857 LEU 858 -0.0000

LEU 858 THR 859 -0.0005

THR 859 VAL 860 0.0003

VAL 860 LEU 861 0.0001

LEU 861 PRO 862 -0.0002

PRO 862 PRO 863 -0.0003

PRO 863 LEU 864 -0.0002

LEU 864 LEU 865 0.0003

LEU 865 THR 866 0.0001

THR 866 ASP 867 0.0002

ASP 867 GLU 868 -0.0002

GLU 868 MET 869 0.0172

MET 869 ILE 870 0.0000

ILE 870 ALA 871 0.0000

ALA 871 GLN 872 -0.0003

GLN 872 TYR 873 -0.0002

TYR 873 THR 874 0.0001

THR 874 SER 875 -0.0001

SER 875 ALA 876 0.0004

ALA 876 LEU 877 -0.0000

LEU 877 LEU 878 0.0004

LEU 878 ALA 879 0.0002

ALA 879 GLY 880 -0.0002

GLY 880 THR 881 0.0001

THR 881 ILE 882 -0.0003

ILE 882 THR 883 -0.0000

THR 883 SER 884 0.0040

SER 884 GLY 885 0.0000

GLY 885 TRP 886 0.0000

TRP 886 THR 887 0.0002

THR 887 PHE 888 0.0000

PHE 888 GLY 889 -0.0002

GLY 889 ALA 890 -0.0002

ALA 890 GLY 891 0.0003

GLY 891 ALA 892 -0.0003

ALA 892 ALA 893 0.0000

ALA 893 LEU 894 -0.0000

LEU 894 GLN 895 0.0003

GLN 895 ILE 896 -0.0001

ILE 896 PRO 897 0.0001

PRO 897 PHE 898 0.0002

PHE 898 ALA 899 -0.0014

ALA 899 MET 900 -0.0002

MET 900 GLN 901 0.0003

GLN 901 MET 902 -0.0001

MET 902 ALA 903 -0.0000

ALA 903 TYR 904 -0.0001

TYR 904 ARG 905 -0.0001

ARG 905 PHE 906 -0.0003

PHE 906 ASN 907 0.0001

ASN 907 GLY 908 0.0004

GLY 908 ILE 909 -0.0000

ILE 909 GLY 910 -0.0002

GLY 910 VAL 911 0.0002

VAL 911 THR 912 0.0003

THR 912 GLN 913 -0.0002

GLN 913 ASN 914 -0.0002

ASN 914 VAL 915 -0.0002

VAL 915 LEU 916 0.0002

LEU 916 TYR 917 0.0002

TYR 917 GLU 918 0.0002

GLU 918 ASN 919 0.0001

ASN 919 GLN 920 0.0001

GLN 920 LYS 921 0.0002

LYS 921 LEU 922 0.0004

LEU 922 ILE 923 0.0004

ILE 923 ALA 924 -0.0002

ALA 924 ASN 925 0.0000

ASN 925 GLN 926 -0.0003

GLN 926 PHE 927 0.0000

PHE 927 ASN 928 -0.0003

ASN 928 SER 929 0.0088

SER 929 ALA 930 -0.0001

ALA 930 ILE 931 0.0003

ILE 931 GLY 932 0.0002

GLY 932 LYS 933 0.0002

LYS 933 ILE 934 -0.0001

ILE 934 GLN 935 0.0001

GLN 935 ASP 936 -0.0001

ASP 936 SER 937 0.0001

SER 937 LEU 938 0.0002

LEU 938 SER 939 -0.0002

SER 939 SER 940 -0.0002

SER 940 THR 941 0.0004

THR 941 ALA 942 -0.0002

ALA 942 SER 943 0.0000

SER 943 ALA 944 -0.0295

ALA 944 LEU 945 0.0001

LEU 945 GLY 946 -0.0004

GLY 946 LYS 947 -0.0001

LYS 947 LEU 948 -0.0002

LEU 948 GLN 949 -0.0002

GLN 949 ASP 950 -0.0002

ASP 950 VAL 951 0.0005

VAL 951 VAL 952 0.0003

VAL 952 ASN 953 -0.0002

ASN 953 GLN 954 0.0002

GLN 954 ASN 955 -0.0000

ASN 955 ALA 956 0.0003

ALA 956 GLN 957 -0.0000

GLN 957 ALA 958 -0.0000

ALA 958 LEU 959 -0.0034

LEU 959 ASN 960 0.0002

ASN 960 THR 961 -0.0002

THR 961 LEU 962 0.0000

LEU 962 VAL 963 0.0004

VAL 963 LYS 964 -0.0001

LYS 964 GLN 965 0.0004

GLN 965 LEU 966 -0.0002

LEU 966 SER 967 0.0002

SER 967 SER 968 0.0000

SER 968 ASN 969 -0.0001

ASN 969 PHE 970 -0.0001

PHE 970 GLY 971 0.0001

GLY 971 ALA 972 -0.0001

ALA 972 ILE 973 -0.0001

ILE 973 SER 974 -0.0430

SER 974 SER 975 0.0000

SER 975 VAL 976 -0.0003

VAL 976 LEU 977 -0.0001

LEU 977 ASN 978 0.0003

ASN 978 ASP 979 0.0002

ASP 979 ILE 980 -0.0004

ILE 980 LEU 981 -0.0001

LEU 981 SER 982 0.0004

SER 982 ARG 983 0.0001

ARG 983 LEU 984 0.0003

LEU 984 ASP 985 0.0002

ASP 985 PRO 986 -0.0003

PRO 986 PRO 987 0.0001

PRO 987 GLU 988 0.0001

GLU 988 ALA 989 -0.0146

ALA 989 GLU 990 0.0002

GLU 990 VAL 991 -0.0001

VAL 991 GLN 992 -0.0001

GLN 992 ILE 993 -0.0001

ILE 993 ASP 994 0.0000

ASP 994 ARG 995 0.0001

ARG 995 LEU 996 0.0000

LEU 996 ILE 997 0.0002

ILE 997 THR 998 0.0000

THR 998 GLY 999 -0.0000

GLY 999 ARG 1000 0.0000

ARG 1000 LEU 1001 -0.0002

LEU 1001 GLN 1002 0.0003

GLN 1002 SER 1003 -0.0000

SER 1003 LEU 1004 0.0009

LEU 1004 GLN 1005 -0.0001

GLN 1005 THR 1006 0.0005

THR 1006 TYR 1007 0.0003

TYR 1007 VAL 1008 -0.0001

VAL 1008 THR 1009 0.0004

THR 1009 GLN 1010 -0.0002

GLN 1010 GLN 1011 0.0004

GLN 1011 LEU 1012 0.0000

LEU 1012 ILE 1013 0.0000

ILE 1013 ARG 1014 -0.0000

ARG 1014 ALA 1015 0.0001

ALA 1015 ALA 1016 -0.0002

ALA 1016 GLU 1017 -0.0003

GLU 1017 ILE 1018 0.0002

ILE 1018 ARG 1019 0.0124

ARG 1019 ALA 1020 -0.0000

ALA 1020 SER 1021 0.0001

SER 1021 ALA 1022 -0.0003

ALA 1022 ASN 1023 -0.0001

ASN 1023 LEU 1024 0.0000

LEU 1024 ALA 1025 -0.0002

ALA 1025 ALA 1026 0.0002

ALA 1026 THR 1027 -0.0002

THR 1027 LYS 1028 -0.0002

LYS 1028 MET 1029 0.0001

MET 1029 SER 1030 0.0003

SER 1030 GLU 1031 -0.0003

GLU 1031 CYS 1032 0.0000

CYS 1032 VAL 1033 -0.0004

VAL 1033 LEU 1034 0.0038

LEU 1034 GLY 1035 0.0000

GLY 1035 GLN 1036 0.0005

GLN 1036 SER 1037 0.0002

SER 1037 LYS 1038 -0.0003

LYS 1038 ARG 1039 -0.0004

ARG 1039 VAL 1040 -0.0001

VAL 1040 ASP 1041 -0.0002

ASP 1041 PHE 1042 0.0003

PHE 1042 CYS 1043 -0.0001

CYS 1043 GLY 1044 0.0002

GLY 1044 LYS 1045 0.0001

LYS 1045 GLY 1046 -0.0003

GLY 1046 TYR 1047 0.0001

TYR 1047 HIS 1048 -0.0003

HIS 1048 LEU 1049 0.0046

LEU 1049 MET 1050 0.0001

MET 1050 SER 1051 -0.0002

SER 1051 PHE 1052 0.0001

PHE 1052 PRO 1053 -0.0000

PRO 1053 GLN 1054 -0.0003

GLN 1054 SER 1055 0.0005

SER 1055 ALA 1056 -0.0001

ALA 1056 PRO 1057 -0.0002

PRO 1057 HIS 1058 0.0001

HIS 1058 GLY 1059 0.0003

GLY 1059 VAL 1060 -0.0000

VAL 1060 VAL 1061 -0.0000

VAL 1061 PHE 1062 0.0000

PHE 1062 LEU 1063 -0.0004

LEU 1063 HIS 1064 -0.0100

HIS 1064 VAL 1065 0.0002

VAL 1065 THR 1066 -0.0001

THR 1066 TYR 1067 0.0001

TYR 1067 VAL 1068 -0.0001

VAL 1068 PRO 1069 0.0002

PRO 1069 ALA 1070 0.0004

ALA 1070 GLN 1071 0.0001

GLN 1071 GLU 1072 0.0003

GLU 1072 LYS 1073 -0.0002

LYS 1073 ASN 1074 -0.0000

ASN 1074 PHE 1075 -0.0002

PHE 1075 THR 1076 0.0004

THR 1076 THR 1077 -0.0002

THR 1077 ALA 1078 -0.0000

ALA 1078 PRO 1079 -0.0015

PRO 1079 ALA 1080 -0.0001

ALA 1080 ILE 1081 0.0002

ILE 1081 CYS 1082 -0.0001

CYS 1082 HIS 1083 0.0002

HIS 1083 ASP 1084 -0.0003

ASP 1084 GLY 1085 0.0003

GLY 1085 LYS 1086 -0.0004

LYS 1086 ALA 1087 0.0001

ALA 1087 HIS 1088 -0.0001

HIS 1088 PHE 1089 -0.0001

PHE 1089 PRO 1090 -0.0000

PRO 1090 ARG 1091 0.0002

ARG 1091 GLU 1092 0.0002

GLU 1092 GLY 1093 -0.0004

GLY 1093 VAL 1094 0.0014

VAL 1094 PHE 1095 0.0003

PHE 1095 VAL 1096 -0.0001

VAL 1096 SER 1097 -0.0002

SER 1097 ASN 1098 0.0002

ASN 1098 GLY 1099 -0.0001

GLY 1099 THR 1100 0.0003

THR 1100 HIS 1101 -0.0003

HIS 1101 TRP 1102 -0.0000

TRP 1102 PHE 1103 -0.0001

PHE 1103 VAL 1104 -0.0001

VAL 1104 THR 1105 0.0002

THR 1105 GLN 1106 -0.0002

GLN 1106 ARG 1107 0.0003

ARG 1107 ASN 1108 0.0000

ASN 1108 PHE 1109 -0.0023

PHE 1109 TYR 1110 0.0003

TYR 1110 GLU 1111 -0.0003

GLU 1111 PRO 1112 0.0002

PRO 1112 GLN 1113 -0.0001

GLN 1113 ILE 1114 0.0005

ILE 1114 ILE 1115 -0.0003

ILE 1115 THR 1116 0.0000

THR 1116 THR 1117 -0.0003

THR 1117 ASP 1118 -0.0001

ASP 1118 ASN 1119 0.0000

ASN 1119 THR 1120 -0.0000

THR 1120 PHE 1121 -0.0000

PHE 1121 VAL 1122 0.0003

VAL 1122 SER 1123 -0.0001

SER 1123 GLY 1124 0.0020

GLY 1124 ASN 1125 -0.0006

ASN 1125 CYS 1126 0.0001

CYS 1126 ASP 1127 -0.0002

ASP 1127 VAL 1128 0.0000

VAL 1128 VAL 1129 -0.0004

VAL 1129 ILE 1130 0.0001

ILE 1130 GLY 1131 -0.0002

GLY 1131 ILE 1132 0.0001

ILE 1132 VAL 1133 -0.0006

VAL 1133 ASN 1134 0.0001

ASN 1134 ASN 1135 0.0003

ASN 1135 THR 1136 -0.0000

THR 1136 VAL 1137 -0.0003

VAL 1137 TYR 1138 0.0000

TYR 1138 ASP 1139 0.0098

ASP 1139 PRO 1140 0.0002

PRO 1140 LEU 1141 0.0005

LEU 1141 GLN 1142 0.0001

GLN 1142 PRO 1143 -0.0001

PRO 1143 GLU 1144 0.0000

GLU 1144 LEU 1145 0.0001

LEU 1145 ASP 1146 -0.0004

ASP 1146 SER 1147 0.0001

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** nome ***

CA strain for 221129135925108001

--- normal mode 7 ---

Should you encounter any unexpected behaviour,
please let us know.

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