Should you encounter any unexpected behaviour,
please let us know.

* Model 4A *

CA strain for 21020920311728206

--- normal mode 12 ---

This graph displays the distance variation between successive pairs of CA atoms in the two extreme conformations that were computed for this mode (DQMIN/DQMAX). Large distance variations can be an indicator for residue pairs that support the important strain in that particular normal mode movement. Note that residue pairs between chain breaks or at flexible ends of the protein may also exhibit large CA-CA distance variations. If more than one residues ae grouped together into a rigid block (NRBL>1), CA-CA distance variations between CA atoms in the same block will be very low.

This feature is still experimental and will be further developped in the future.

CA i CA i+1 vari
THR 13 VAL 14 -0.0000

VAL 14 PHE 15 0.0001

PHE 15 THR 16 -0.0001

THR 16 ARG 17 0.0002

ARG 17 ILE 18 0.0000

ILE 18 LEU 19 0.0002

LEU 19 ASP 20 0.0002

ASP 20 ARG 21 -0.0000

ARG 21 LEU 22 -0.0097

LEU 22 LEU 23 -0.0000

LEU 23 ASP 24 -0.0002

ASP 24 GLY 25 0.0002

GLY 25 TYR 26 -0.0002

TYR 26 ASP 27 0.0000

ASP 27 ASN 28 -0.0002

ASN 28 ARG 29 0.0001

ARG 29 LEU 30 0.0000

LEU 30 ARG 31 -0.0011

ARG 31 PRO 32 0.0001

PRO 32 GLY 33 -0.0002

GLY 33 LEU 34 -0.0003

LEU 34 GLY 35 -0.0003

GLY 35 GLU 36 0.0001

GLU 36 ARG 37 0.0000

ARG 37 VAL 38 0.0003

VAL 38 THR 39 -0.0004

THR 39 GLU 40 -0.0363

GLU 40 VAL 41 0.0003

VAL 41 LYS 42 0.0001

LYS 42 THR 43 0.0001

THR 43 ASP 44 0.0001

ASP 44 ILE 45 -0.0001

ILE 45 PHE 46 -0.0002

PHE 46 VAL 47 -0.0002

VAL 47 THR 48 -0.0003

THR 48 SER 49 -0.0868

SER 49 PHE 50 -0.0003

PHE 50 GLY 51 0.0002

GLY 51 PRO 52 -0.0001

PRO 52 VAL 53 -0.0000

VAL 53 SER 54 -0.0002

SER 54 ASP 55 -0.0002

ASP 55 HIS 56 0.0002

HIS 56 ASP 57 0.0001

ASP 57 MET 58 -0.0225

MET 58 GLU 59 0.0000

GLU 59 TYR 60 0.0001

TYR 60 THR 61 0.0001

THR 61 ILE 62 -0.0004

ILE 62 ASP 63 0.0004

ASP 63 VAL 64 0.0000

VAL 64 PHE 65 -0.0002

PHE 65 PHE 66 -0.0001

PHE 66 ARG 67 -0.0564

ARG 67 GLN 68 -0.0001

GLN 68 SER 69 -0.0001

SER 69 TRP 70 -0.0001

TRP 70 LYS 71 0.0000

LYS 71 ASP 72 0.0004

ASP 72 GLU 73 -0.0000

GLU 73 ARG 74 0.0003

ARG 74 LEU 75 0.0002

LEU 75 LYS 76 -0.0234

LYS 76 PHE 77 0.0000

PHE 77 LYS 78 -0.0000

LYS 78 GLY 79 0.0002

GLY 79 PRO 80 -0.0002

PRO 80 MET 81 -0.0003

MET 81 THR 82 0.0001

THR 82 VAL 83 -0.0001

VAL 83 LEU 84 0.0001

LEU 84 ARG 85 -0.0207

ARG 85 LEU 86 -0.0005

LEU 86 ASN 87 0.0004

ASN 87 ASN 88 0.0000

ASN 88 LEU 89 -0.0001

LEU 89 MET 90 0.0002

MET 90 ALA 91 0.0003

ALA 91 SER 92 -0.0004

SER 92 LYS 93 0.0000

LYS 93 ILE 94 0.0144

ILE 94 TRP 95 -0.0001

TRP 95 THR 96 0.0002

THR 96 PRO 97 0.0001

PRO 97 ASP 98 0.0002

ASP 98 THR 99 0.0004

THR 99 PHE 100 -0.0001

PHE 100 PHE 101 -0.0005

PHE 101 HIS 102 -0.0002

HIS 102 ASN 103 -0.0015

ASN 103 GLY 104 -0.0002

GLY 104 LYS 105 0.0002

LYS 105 LYS 106 0.0002

LYS 106 SER 107 -0.0002

SER 107 VAL 108 0.0000

VAL 108 ALA 109 -0.0000

ALA 109 HIS 110 -0.0003

HIS 110 ASN 111 -0.0002

ASN 111 MET 112 0.0237

MET 112 THR 113 -0.0002

THR 113 MET 114 -0.0001

MET 114 PRO 115 0.0003

PRO 115 ASN 116 0.0003

ASN 116 LYS 117 -0.0002

LYS 117 LEU 118 0.0000

LEU 118 LEU 119 -0.0004

LEU 119 ARG 120 -0.0003

ARG 120 ILE 121 -0.0003

ILE 121 THR 122 -0.0001

THR 122 GLU 123 0.0000

GLU 123 ASP 124 -0.0002

ASP 124 GLY 125 0.0002

GLY 125 THR 126 0.0003

THR 126 LEU 127 -0.0001

LEU 127 LEU 128 0.0000

LEU 128 TYR 129 0.0004

TYR 129 THR 130 -0.0240

THR 130 MET 131 -0.0000

MET 131 ARG 132 -0.0000

ARG 132 LEU 133 0.0001

LEU 133 THR 134 0.0004

THR 134 VAL 135 0.0001

VAL 135 ARG 136 -0.0000

ARG 136 ALA 137 0.0003

ALA 137 GLU 138 0.0002

GLU 138 CYS 139 0.1013

CYS 139 PRO 140 -0.0001

PRO 140 MET 141 0.0001

MET 141 HIS 142 -0.0001

HIS 142 LEU 143 -0.0001

LEU 143 GLU 144 -0.0003

GLU 144 ASP 145 0.0001

ASP 145 PHE 146 -0.0001

PHE 146 PRO 147 0.0002

PRO 147 MET 148 -0.0161

MET 148 ASP 149 -0.0001

ASP 149 ALA 150 0.0001

ALA 150 HIS 151 -0.0002

HIS 151 ALA 152 0.0004

ALA 152 CYS 153 0.0001

CYS 153 PRO 154 -0.0001

PRO 154 LEU 155 -0.0001

LEU 155 LYS 156 -0.0003

LYS 156 PHE 157 0.0872

PHE 157 GLY 158 0.0001

GLY 158 SER 159 -0.0001

SER 159 TYR 160 0.0000

TYR 160 ALA 161 0.0000

ALA 161 TYR 162 -0.0001

TYR 162 THR 163 0.0001

THR 163 ARG 164 0.0003

ARG 164 ALA 165 0.0002

ALA 165 GLU 166 0.0045

GLU 166 VAL 167 -0.0001

VAL 167 VAL 168 0.0002

VAL 168 TYR 169 -0.0001

TYR 169 GLU 170 -0.0001

GLU 170 TRP 171 0.0000

TRP 171 THR 172 0.0001

THR 172 ARG 173 -0.0001

ARG 173 GLU 174 0.0001

GLU 174 PRO 175 -0.0301

PRO 175 ALA 176 -0.0001

ALA 176 ARG 177 0.0002

ARG 177 SER 178 0.0000

SER 178 VAL 179 0.0003

VAL 179 VAL 180 0.0000

VAL 180 VAL 181 -0.0001

VAL 181 ALA 182 -0.0002

ALA 182 GLU 183 0.0002

GLU 183 ASP 184 0.0225

ASP 184 GLY 185 0.0001

GLY 185 SER 186 0.0002

SER 186 ARG 187 -0.0002

ARG 187 LEU 188 -0.0004

LEU 188 ASN 189 -0.0000

ASN 189 GLN 190 -0.0000

GLN 190 TYR 191 -0.0001

TYR 191 ASP 192 -0.0001

ASP 192 LEU 193 -0.0432

LEU 193 LEU 194 -0.0001

LEU 194 GLY 195 -0.0005

GLY 195 GLN 196 0.0001

GLN 196 THR 197 -0.0002

THR 197 VAL 198 0.0001

VAL 198 ASP 199 0.0003

ASP 199 SER 200 -0.0001

SER 200 GLY 201 0.0001

GLY 201 ILE 202 0.0771

ILE 202 VAL 203 -0.0000

VAL 203 GLN 204 -0.0003

GLN 204 SER 205 0.0001

SER 205 SER 206 -0.0004

SER 206 THR 207 -0.0001

THR 207 GLY 208 0.0004

GLY 208 GLU 209 -0.0001

GLU 209 TYR 210 0.0003

TYR 210 VAL 211 -0.0262

VAL 211 VAL 212 -0.0003

VAL 212 MET 213 0.0001

MET 213 THR 214 0.0002

THR 214 THR 215 -0.0004

THR 215 HIS 216 0.0000

HIS 216 PHE 217 0.0002

PHE 217 HIS 218 0.0001

HIS 218 LEU 219 0.0001

LEU 219 LYS 220 -0.0017

LYS 220 ARG 221 -0.0002

ARG 221 LYS 222 -0.0000

LYS 222 ILE 223 -0.0002

ILE 223 GLY 224 0.0003

GLY 224 TYR 225 -0.0002

TYR 225 PHE 226 0.0003

PHE 226 VAL 227 -0.0000

VAL 227 ILE 228 -0.0002

ILE 228 GLN 229 -0.0055

GLN 229 THR 230 -0.0003

THR 230 TYR 231 -0.0001

TYR 231 LEU 232 -0.0004

LEU 232 PRO 233 0.0002

PRO 233 CYS 234 0.0002

CYS 234 ILE 235 -0.0002

ILE 235 MET 236 0.0001

MET 236 THR 237 -0.0004

THR 237 VAL 238 -0.0051

VAL 238 ILE 239 -0.0003

ILE 239 LEU 240 0.0000

LEU 240 SER 241 -0.0001

SER 241 GLN 242 -0.0001

GLN 242 VAL 243 -0.0002

VAL 243 SER 244 0.0003

SER 244 PHE 245 0.0000

PHE 245 TRP 246 -0.0001

TRP 246 LEU 247 0.0245

LEU 247 ASN 248 0.0001

ASN 248 ARG 249 0.0000

ARG 249 GLU 250 -0.0000

GLU 250 SER 251 -0.0001

SER 251 VAL 252 0.0001

VAL 252 PRO 253 0.0001

PRO 253 ALA 254 -0.0002

ALA 254 ARG 255 -0.0000

ARG 255 THR 256 0.0095

THR 256 VAL 257 -0.0003

VAL 257 PHE 258 0.0001

PHE 258 GLY 259 -0.0000

GLY 259 VAL 260 0.0000

VAL 260 THR 261 0.0001

THR 261 THR 262 0.0004

THR 262 VAL 263 -0.0001

VAL 263 LEU 264 0.0003

LEU 264 THR 265 -0.0727

THR 265 MET 266 0.0003

MET 266 THR 267 -0.0000

THR 267 THR 268 -0.0004

THR 268 LEU 269 0.0004

LEU 269 SER 270 -0.0001

SER 270 ILE 271 0.0000

ILE 271 SER 272 -0.0004

SER 272 ALA 273 0.0002

ALA 273 ARG 274 0.1288

ARG 274 ASN 275 -0.0000

ASN 275 SER 276 -0.0002

SER 276 LEU 277 0.0001

LEU 277 PRO 278 0.0002

PRO 278 LYS 279 0.0001

LYS 279 VAL 280 0.0001

VAL 280 ALA 281 0.0001

ALA 281 TYR 282 -0.0002

TYR 282 ALA 283 0.2619

ALA 283 THR 284 -0.0002

THR 284 ALA 285 0.0002

ALA 285 MET 286 0.0001

MET 286 ASP 287 0.0003

ASP 287 TRP 288 -0.0000

TRP 288 PHE 289 -0.0001

PHE 289 ILE 290 0.0001

ILE 290 ALA 291 0.0003

ALA 291 VAL 292 0.0767

VAL 292 CYS 293 0.0000

CYS 293 TYR 294 -0.0002

TYR 294 ALA 295 0.0002

ALA 295 PHE 296 -0.0003

PHE 296 VAL 297 -0.0000

VAL 297 PHE 298 -0.0001

PHE 298 SER 299 0.0001

SER 299 ALA 300 -0.0002

ALA 300 LEU 301 -0.0384

LEU 301 ILE 302 0.0000

ILE 302 GLU 303 0.0001

GLU 303 PHE 304 -0.0005

PHE 304 ALA 305 0.0000

ALA 305 THR 306 -0.0002

THR 306 VAL 307 0.0001

VAL 307 ASN 308 0.0001

ASN 308 TYR 309 0.0000

TYR 309 PHE 310 -0.0586

PHE 310 THR 311 0.0000

THR 311 LYS 312 -0.0000

LYS 312 ARG 313 0.0001

ARG 313 GLY 314 -0.0001

GLY 314 TYR 315 0.0000

TYR 315 ALA 316 -0.0000

ALA 316 TRP 317 0.0002

TRP 317 ASP 318 -0.0002

ASP 318 GLY 319 -0.0035

GLY 319 LYS 320 -0.0000

LYS 320 SER 321 0.0003

SER 321 LYS 384 -0.0269

LYS 384 THR 385 0.0000

THR 385 PHE 386 -0.0004

PHE 386 ASN 387 -0.0000

ASN 387 SER 388 0.0000

SER 388 VAL 389 0.0002

VAL 389 SER 390 -0.0001

SER 390 LYS 391 0.0004

LYS 391 ILE 392 -0.0002

ILE 392 ASP 393 -0.0408

ASP 393 ARG 394 -0.0000

ARG 394 LEU 395 -0.0002

LEU 395 SER 396 0.0001

SER 396 ARG 397 0.0001

ARG 397 ILE 398 -0.0001

ILE 398 ALA 399 -0.0000

ALA 399 PHE 400 -0.0001

PHE 400 PRO 401 -0.0000

PRO 401 LEU 402 -0.0171

LEU 402 LEU 403 -0.0004

LEU 403 PHE 404 -0.0002

PHE 404 GLY 405 -0.0001

GLY 405 ILE 406 0.0001

ILE 406 PHE 407 0.0001

PHE 407 ASN 408 -0.0004

ASN 408 LEU 409 -0.0001

LEU 409 VAL 410 -0.0002

VAL 410 TYR 411 0.0716

TYR 411 TRP 412 0.0001

TRP 412 ALA 413 0.0002

ALA 413 THR 414 0.0001

THR 414 TYR 415 0.0002

TYR 415 LEU 416 0.0001

LEU 416 ASN 417 0.0004

ASN 417 ARG 418 -0.0003

ARG 418 ASN 8 0.0130

ASN 8 MET 9 -0.0003

MET 9 SER 10 0.0002

SER 10 PHE 11 -0.0000

PHE 11 VAL 12 -0.0003

VAL 12 LYS 13 0.0001

LYS 13 GLU 14 0.0000

GLU 14 THR 15 -0.0001

THR 15 VAL 16 -0.0001

VAL 16 ASP 17 0.0050

ASP 17 LYS 18 0.0003

LYS 18 LEU 19 0.0002

LEU 19 LEU 20 0.0001

LEU 20 LYS 21 0.0001

LYS 21 GLY 22 -0.0005

GLY 22 TYR 23 0.0002

TYR 23 ASP 24 0.0003

ASP 24 ILE 25 -0.0002

ILE 25 ARG 26 -0.0053

ARG 26 LEU 27 -0.0000

LEU 27 ARG 28 -0.0002

ARG 28 PRO 29 0.0003

PRO 29 ASP 30 -0.0001

ASP 30 PHE 31 -0.0002

PHE 31 GLY 32 -0.0003

GLY 32 GLY 33 0.0001

GLY 33 PRO 34 -0.0000

PRO 34 PRO 35 -0.0167

PRO 35 VAL 36 0.0005

VAL 36 CYS 37 -0.0003

CYS 37 VAL 38 -0.0002

VAL 38 GLY 39 0.0003

GLY 39 MET 40 0.0001

MET 40 ASN 41 -0.0004

ASN 41 ILE 42 0.0005

ILE 42 ASP 43 0.0001

ASP 43 ILE 44 -0.0080

ILE 44 ALA 45 0.0000

ALA 45 SER 46 -0.0001

SER 46 ILE 47 -0.0003

ILE 47 ASP 48 0.0002

ASP 48 MET 49 -0.0002

MET 49 VAL 50 -0.0001

VAL 50 SER 51 -0.0005

SER 51 GLU 52 0.0003

GLU 52 VAL 53 0.0303

VAL 53 ASN 54 0.0003

ASN 54 MET 55 0.0003

MET 55 ASP 56 -0.0001

ASP 56 TYR 57 -0.0000

TYR 57 THR 58 0.0001

THR 58 LEU 59 -0.0001

LEU 59 THR 60 -0.0002

THR 60 MET 61 0.0004

MET 61 TYR 62 0.0473

TYR 62 PHE 63 0.0001

PHE 63 GLN 64 0.0002

GLN 64 GLN 65 -0.0001

GLN 65 TYR 66 0.0001

TYR 66 TRP 67 0.0001

TRP 67 ARG 68 -0.0003

ARG 68 ASP 69 0.0001

ASP 69 LYS 70 -0.0002

LYS 70 ARG 71 -0.0385

ARG 71 LEU 72 0.0006

LEU 72 ALA 73 -0.0000

ALA 73 TYR 74 0.0000

TYR 74 SER 75 0.0000

SER 75 GLY 76 -0.0003

GLY 76 ILE 77 0.0001

ILE 77 PRO 78 -0.0003

PRO 78 LEU 79 0.0001

LEU 79 ASN 80 -0.0123

ASN 80 LEU 81 0.0002

LEU 81 THR 82 0.0002

THR 82 LEU 83 0.0001

LEU 83 ASP 84 0.0000

ASP 84 ASN 85 -0.0000

ASN 85 ARG 86 0.0000

ARG 86 VAL 87 0.0003

VAL 87 ALA 88 0.0002

ALA 88 ASP 89 0.0169

ASP 89 GLN 90 -0.0002

GLN 90 LEU 91 0.0000

LEU 91 TRP 92 0.0001

TRP 92 VAL 93 -0.0002

VAL 93 PRO 94 0.0003

PRO 94 ASP 95 0.0002

ASP 95 THR 96 0.0001

THR 96 TYR 97 -0.0002

TYR 97 PHE 98 -0.0148

PHE 98 LEU 99 0.0000

LEU 99 ASN 100 0.0001

ASN 100 ASP 101 -0.0001

ASP 101 LYS 102 0.0001

LYS 102 LYS 103 0.0001

LYS 103 SER 104 0.0003

SER 104 PHE 105 0.0002

PHE 105 VAL 106 -0.0005

VAL 106 HIS 107 -0.0100

HIS 107 GLY 108 -0.0005

GLY 108 VAL 109 0.0002

VAL 109 THR 110 -0.0001

THR 110 VAL 111 -0.0001

VAL 111 LYS 112 0.0003

LYS 112 ASN 113 0.0000

ASN 113 ARG 114 -0.0001

ARG 114 MET 115 -0.0002

MET 115 ILE 116 -0.0553

ILE 116 ARG 117 -0.0001

ARG 117 LEU 118 -0.0000

LEU 118 HIS 119 0.0001

HIS 119 PRO 120 -0.0002

PRO 120 ASP 121 0.0001

ASP 121 GLY 122 0.0005

GLY 122 THR 123 0.0001

THR 123 VAL 124 -0.0002

VAL 124 LEU 125 -0.0200

LEU 125 TYR 126 -0.0002

TYR 126 GLY 127 0.0002

GLY 127 LEU 128 -0.0002

LEU 128 ARG 129 0.0001

ARG 129 ILE 130 0.0001

ILE 130 THR 131 -0.0000

THR 131 THR 132 0.0001

THR 132 THR 133 -0.0000

THR 133 ALA 134 0.0987

ALA 134 ALA 135 0.0005

ALA 135 CYS 136 0.0003

CYS 136 MET 137 -0.0001

MET 137 MET 138 0.0001

MET 138 ASP 139 0.0002

ASP 139 LEU 140 -0.0002

LEU 140 ARG 141 0.0000

ARG 141 ARG 142 0.0001

ARG 142 TYR 143 -0.0383

TYR 143 PRO 144 0.0002

PRO 144 LEU 145 -0.0004

LEU 145 ASP 146 -0.0001

ASP 146 GLU 147 0.0002

GLU 147 GLN 148 0.0002

GLN 148 ASN 149 -0.0002

ASN 149 CYS 150 -0.0001

CYS 150 THR 151 0.0002

THR 151 LEU 152 -0.0274

LEU 152 GLU 153 0.0000

GLU 153 ILE 154 0.0003

ILE 154 GLU 155 0.0003

GLU 155 SER 156 0.0001

SER 156 TYR 157 -0.0004

TYR 157 GLY 158 -0.0003

GLY 158 TYR 159 -0.0004

TYR 159 THR 160 -0.0000

THR 160 THR 161 0.0333

THR 161 ASP 162 0.0003

ASP 162 ASP 163 -0.0003

ASP 163 ILE 164 -0.0000

ILE 164 GLU 165 0.0001

GLU 165 PHE 166 -0.0001

PHE 166 TYR 167 0.0001

TYR 167 TRP 168 0.0002

TRP 168 ARG 169 -0.0004

ARG 169 GLY 170 -0.0180

GLY 170 GLY 171 -0.0002

GLY 171 ASP 172 -0.0001

ASP 172 LYS 173 -0.0003

LYS 173 ALA 174 0.0000

ALA 174 VAL 175 0.0000

VAL 175 THR 176 0.0003

THR 176 GLY 177 -0.0000

GLY 177 VAL 178 0.0001

VAL 178 GLU 179 -0.0204

GLU 179 ARG 180 -0.0001

ARG 180 ILE 181 -0.0003

ILE 181 GLU 182 -0.0002

GLU 182 LEU 183 -0.0000

LEU 183 PRO 184 -0.0003

PRO 184 GLN 185 -0.0002

GLN 185 PHE 186 0.0001

PHE 186 SER 187 -0.0004

SER 187 ILE 188 -0.1151

ILE 188 VAL 189 0.0001

VAL 189 GLU 190 -0.0001

GLU 190 HIS 191 -0.0002

HIS 191 ARG 192 0.0001

ARG 192 LEU 193 0.0003

LEU 193 VAL 194 -0.0000

VAL 194 SER 195 0.0000

SER 195 ARG 196 0.0002

ARG 196 ASN 197 -0.0262

ASN 197 VAL 198 -0.0001

VAL 198 VAL 199 0.0001

VAL 199 PHE 200 -0.0001

PHE 200 ALA 201 -0.0003

ALA 201 THR 202 -0.0001

THR 202 GLY 203 0.0000

GLY 203 ALA 204 -0.0003

ALA 204 TYR 205 0.0002

TYR 205 PRO 206 -0.0249

PRO 206 ARG 207 0.0002

ARG 207 LEU 208 -0.0003

LEU 208 SER 209 0.0003

SER 209 LEU 210 -0.0004

LEU 210 SER 211 0.0000

SER 211 PHE 212 0.0000

PHE 212 ARG 213 0.0000

ARG 213 LEU 214 0.0004

LEU 214 LYS 215 -0.1222

LYS 215 ARG 216 -0.0002

ARG 216 ASN 217 0.0001

ASN 217 ILE 218 -0.0002

ILE 218 GLY 219 0.0003

GLY 219 TYR 220 0.0001

TYR 220 PHE 221 0.0000

PHE 221 ILE 222 0.0000

ILE 222 LEU 223 0.0002

LEU 223 GLN 224 -0.0241

GLN 224 THR 225 -0.0000

THR 225 TYR 226 0.0001

TYR 226 MET 227 0.0005

MET 227 PRO 228 -0.0000

PRO 228 SER 229 0.0003

SER 229 ILE 230 0.0001

ILE 230 LEU 231 -0.0001

LEU 231 ILE 232 0.0000

ILE 232 THR 233 0.0287

THR 233 ILE 234 -0.0004

ILE 234 LEU 235 -0.0001

LEU 235 SER 236 0.0003

SER 236 TRP 237 0.0002

TRP 237 VAL 238 0.0004

VAL 238 SER 239 -0.0001

SER 239 PHE 240 -0.0002

PHE 240 TRP 241 -0.0001

TRP 241 ILE 242 0.0264

ILE 242 ASN 243 0.0002

ASN 243 TYR 244 0.0001

TYR 244 ASP 245 -0.0002

ASP 245 ALA 246 0.0000

ALA 246 SER 247 0.0001

SER 247 ALA 248 -0.0001

ALA 248 ALA 249 -0.0003

ALA 249 ARG 250 -0.0001

ARG 250 VAL 251 0.0038

VAL 251 ALA 252 0.0000

ALA 252 LEU 253 -0.0003

LEU 253 GLY 254 -0.0001

GLY 254 ILE 255 -0.0003

ILE 255 THR 256 -0.0001

THR 256 THR 257 -0.0000

THR 257 VAL 258 -0.0003

VAL 258 LEU 259 -0.0001

LEU 259 THR 260 -0.0319

THR 260 MET 261 0.0002

MET 261 THR 262 0.0000

THR 262 THR 263 0.0003

THR 263 ILE 264 0.0002

ILE 264 ASN 265 -0.0003

ASN 265 THR 266 -0.0004

THR 266 HIS 267 0.0004

HIS 267 LEU 268 0.0000

LEU 268 ARG 269 -0.0139

ARG 269 GLU 270 -0.0004

GLU 270 THR 271 0.0002

THR 271 LEU 272 0.0000

LEU 272 PRO 273 -0.0003

PRO 273 LYS 274 0.0002

LYS 274 ILE 275 0.0001

ILE 275 PRO 276 0.0001

PRO 276 TYR 277 -0.0001

TYR 277 VAL 278 0.0548

VAL 278 LYS 279 -0.0001

LYS 279 ALA 280 0.0002

ALA 280 ILE 281 0.0002

ILE 281 ASP 282 -0.0002

ASP 282 MET 283 0.0003

MET 283 TYR 284 0.0000

TYR 284 LEU 285 -0.0002

LEU 285 MET 286 0.0001

MET 286 GLY 287 0.0809

GLY 287 CYS 288 0.0001

CYS 288 PHE 289 -0.0002

PHE 289 VAL 290 -0.0000

VAL 290 PHE 291 0.0000

PHE 291 VAL 292 0.0002

VAL 292 PHE 293 -0.0001

PHE 293 LEU 294 0.0004

LEU 294 ALA 295 -0.0001

ALA 295 LEU 296 -0.0079

LEU 296 LEU 297 -0.0003

LEU 297 GLU 298 0.0002

GLU 298 TYR 299 -0.0000

TYR 299 ALA 300 -0.0003

ALA 300 PHE 301 0.0001

PHE 301 VAL 302 -0.0001

VAL 302 ASN 303 -0.0002

ASN 303 TYR 304 -0.0000

TYR 304 ILE 305 0.0326

ILE 305 PHE 306 0.0000

PHE 306 PHE 307 -0.0004

PHE 307 GLY 308 0.0000

GLY 308 ARG 309 -0.0001

ARG 309 GLY 310 -0.0001

GLY 310 PRO 311 0.0001

PRO 311 GLN 312 0.0003

GLN 312 ARG 313 0.0003

ARG 313 THR 418 0.0883

THR 418 ASP 419 0.0001

ASP 419 VAL 420 -0.0003

VAL 420 ASN 421 0.0001

ASN 421 ALA 422 0.0002

ALA 422 ILE 423 0.0000

ILE 423 ASP 424 -0.0003

ASP 424 ARG 425 -0.0004

ARG 425 TRP 426 0.0002

TRP 426 SER 427 0.0547

SER 427 ARG 428 -0.0001

ARG 428 ILE 429 -0.0002

ILE 429 VAL 430 0.0001

VAL 430 PHE 431 0.0001

PHE 431 PRO 432 0.0003

PRO 432 PHE 433 -0.0000

PHE 433 THR 434 -0.0000

THR 434 PHE 435 0.0002

PHE 435 SER 436 -0.0036

SER 436 LEU 437 -0.0004

LEU 437 PHE 438 -0.0002

PHE 438 ASN 439 -0.0001

ASN 439 LEU 440 -0.0001

LEU 440 VAL 441 -0.0000

VAL 441 TYR 442 0.0002

TYR 442 TRP 443 -0.0003

TRP 443 LEU 444 -0.0000

LEU 444 TYR 445 0.0065

TYR 445 TYR 446 -0.0003

TYR 446 VAL 447 -0.0003

VAL 447 ASP 26 0.0411

ASP 26 VAL 27 0.0000

VAL 27 THR 28 0.0001

THR 28 VAL 29 -0.0002

VAL 29 ILE 30 0.0001

ILE 30 LEU 31 -0.0001

LEU 31 ASN 32 0.0001

ASN 32 ASN 33 0.0002

ASN 33 LEU 34 -0.0001

LEU 34 LEU 35 -0.0170

LEU 35 GLU 36 0.0001

GLU 36 GLY 37 0.0003

GLY 37 TYR 38 0.0003

TYR 38 ASP 39 0.0001

ASP 39 ASN 40 -0.0000

ASN 40 LYS 41 -0.0001

LYS 41 LEU 42 0.0002

LEU 42 ARG 43 0.0000

ARG 43 PRO 44 -0.0064

PRO 44 ASP 45 0.0002

ASP 45 ILE 46 -0.0000

ILE 46 GLY 47 0.0001

GLY 47 VAL 48 0.0001

VAL 48 LYS 49 -0.0003

LYS 49 PRO 50 0.0003

PRO 50 THR 51 -0.0000

THR 51 LEU 52 -0.0002

LEU 52 ILE 53 -0.0150

ILE 53 HIS 54 -0.0002

HIS 54 THR 55 0.0001

THR 55 ASP 56 0.0005

ASP 56 MET 57 0.0001

MET 57 TYR 58 -0.0001

TYR 58 VAL 59 0.0002

VAL 59 ASN 60 0.0002

ASN 60 SER 61 0.0003

SER 61 ILE 62 0.1473

ILE 62 GLY 63 -0.0001

GLY 63 PRO 64 0.0005

PRO 64 VAL 65 -0.0002

VAL 65 ASN 66 0.0000

ASN 66 ALA 67 -0.0000

ALA 67 ILE 68 -0.0002

ILE 68 ASN 69 -0.0002

ASN 69 MET 70 -0.0000

MET 70 GLU 71 0.1236

GLU 71 TYR 72 -0.0002

TYR 72 THR 73 0.0001

THR 73 ILE 74 0.0001

ILE 74 ASP 75 -0.0001

ASP 75 ILE 76 -0.0000

ILE 76 PHE 77 0.0001

PHE 77 PHE 78 0.0001

PHE 78 ALA 79 -0.0001

ALA 79 GLN 80 0.0228

GLN 80 THR 81 0.0004

THR 81 TRP 82 -0.0002

TRP 82 TYR 83 -0.0004

TYR 83 ASP 84 0.0001

ASP 84 ARG 85 0.0000

ARG 85 ARG 86 -0.0002

ARG 86 LEU 87 0.0003

LEU 87 LYS 88 -0.0001

LYS 88 PHE 89 0.0057

PHE 89 ASN 90 0.0003

ASN 90 SER 91 -0.0001

SER 91 THR 92 -0.0001

THR 92 ILE 93 -0.0001

ILE 93 LYS 94 -0.0002

LYS 94 VAL 95 0.0001

VAL 95 LEU 96 -0.0001

LEU 96 ARG 97 -0.0001

ARG 97 LEU 98 -0.0163

LEU 98 ASN 99 0.0003

ASN 99 SER 100 -0.0000

SER 100 ASN 101 -0.0002

ASN 101 MET 102 0.0001

MET 102 VAL 103 -0.0002

VAL 103 GLY 104 -0.0000

GLY 104 LYS 105 -0.0001

LYS 105 ILE 106 0.0001

ILE 106 TRP 107 0.0039

TRP 107 ILE 108 -0.0000

ILE 108 PRO 109 0.0001

PRO 109 ASP 110 0.0003

ASP 110 THR 111 -0.0003

THR 111 PHE 112 -0.0003

PHE 112 PHE 113 -0.0002

PHE 113 ARG 114 0.0002

ARG 114 ASN 115 -0.0001

ASN 115 SER 116 0.0404

SER 116 LYS 117 -0.0004

LYS 117 LYS 118 -0.0002

LYS 118 ALA 119 -0.0000

ALA 119 ASP 120 -0.0002

ASP 120 ALA 121 0.0004

ALA 121 HIS 122 -0.0000

HIS 122 TRP 123 0.0002

TRP 123 ILE 124 -0.0003

ILE 124 THR 125 0.0168

THR 125 THR 126 0.0002

THR 126 PRO 127 0.0001

PRO 127 ASN 128 -0.0002

ASN 128 ARG 129 0.0002

ARG 129 MET 130 0.0001

MET 130 LEU 131 -0.0001

LEU 131 ARG 132 -0.0001

ARG 132 ILE 133 0.0002

ILE 133 TRP 134 -0.0341

TRP 134 ASN 135 -0.0000

ASN 135 ASP 136 0.0003

ASP 136 GLY 137 0.0001

GLY 137 ARG 138 0.0003

ARG 138 VAL 139 -0.0000

VAL 139 LEU 140 0.0002

LEU 140 TYR 141 0.0001

TYR 141 THR 142 0.0001

THR 142 LEU 143 0.0464

LEU 143 ARG 144 -0.0003

ARG 144 LEU 145 0.0002

LEU 145 THR 146 -0.0001

THR 146 ILE 147 -0.0005

ILE 147 ASP 148 0.0004

ASP 148 ALA 149 -0.0001

ALA 149 GLU 150 0.0002

GLU 150 CYS 151 0.0002

CYS 151 GLN 152 0.1076

GLN 152 LEU 153 -0.0002

LEU 153 GLN 154 -0.0001

GLN 154 LEU 155 0.0002

LEU 155 HIS 156 -0.0001

HIS 156 ASN 157 -0.0000

ASN 157 PHE 158 0.0002

PHE 158 PRO 159 -0.0000

PRO 159 MET 160 0.0003

MET 160 ASP 161 0.0132

ASP 161 GLU 162 -0.0003

GLU 162 HIS 163 -0.0002

HIS 163 SER 164 0.0002

SER 164 CYS 165 0.0002

CYS 165 PRO 166 0.0000

PRO 166 LEU 167 -0.0001

LEU 167 GLU 168 0.0001

GLU 168 PHE 169 0.0001

PHE 169 SER 170 -0.0904

SER 170 SER 171 0.0001

SER 171 TYR 172 -0.0004

TYR 172 GLY 173 0.0000

GLY 173 TYR 174 0.0002

TYR 174 PRO 175 -0.0002

PRO 175 ARG 176 0.0002

ARG 176 GLU 177 0.0001

GLU 177 GLU 178 -0.0002

GLU 178 ILE 179 -0.0079

ILE 179 VAL 180 -0.0004

VAL 180 TYR 181 0.0001

TYR 181 GLN 182 -0.0000

GLN 182 TRP 183 -0.0001

TRP 183 LYS 184 -0.0000

LYS 184 ARG 185 -0.0001

ARG 185 SER 186 0.0001

SER 186 SER 187 -0.0004

SER 187 VAL 188 -0.0039

VAL 188 GLU 189 -0.0002

GLU 189 VAL 190 -0.0003

VAL 190 GLY 191 -0.0002

GLY 191 ASP 192 0.0003

ASP 192 THR 193 -0.0001

THR 193 ARG 194 -0.0007

ARG 194 SER 195 0.0001

SER 195 TRP 196 0.0003

TRP 196 ARG 197 0.0486

ARG 197 LEU 198 -0.0001

LEU 198 TYR 199 0.0000

TYR 199 GLN 200 0.0002

GLN 200 PHE 201 0.0002

PHE 201 SER 202 -0.0001

SER 202 PHE 203 0.0003

PHE 203 VAL 204 0.0003

VAL 204 GLY 205 0.0003

GLY 205 LEU 206 0.0556

LEU 206 ARG 207 -0.0004

ARG 207 ASN 208 -0.0002

ASN 208 THR 209 -0.0002

THR 209 THR 210 0.0001

THR 210 GLU 211 -0.0000

GLU 211 VAL 212 0.0002

VAL 212 VAL 213 0.0000

VAL 213 LYS 214 -0.0003

LYS 214 THR 215 0.0353

THR 215 THR 216 -0.0003

THR 216 SER 217 0.0000

SER 217 GLY 218 0.0001

GLY 218 ASP 219 -0.0000

ASP 219 TYR 220 0.0002

TYR 220 VAL 221 0.0000

VAL 221 VAL 222 -0.0002

VAL 222 MET 223 -0.0002

MET 223 SER 224 -0.0635

SER 224 VAL 225 0.0001

VAL 225 TYR 226 0.0002

TYR 226 PHE 227 0.0001

PHE 227 ASP 228 -0.0002

ASP 228 LEU 229 -0.0004

LEU 229 SER 230 -0.0001

SER 230 ARG 231 0.0003

ARG 231 ARG 232 -0.0003

ARG 232 MET 233 -0.0023

MET 233 GLY 234 -0.0001

GLY 234 TYR 235 0.0000

TYR 235 PHE 236 0.0001

PHE 236 THR 237 0.0002

THR 237 ILE 238 -0.0001

ILE 238 GLN 239 -0.0000

GLN 239 THR 240 0.0002

THR 240 TYR 241 0.0001

TYR 241 ILE 242 -0.1217

ILE 242 PRO 243 -0.0003

PRO 243 CYS 244 0.0000

CYS 244 THR 245 0.0005

THR 245 LEU 246 0.0003

LEU 246 ILE 247 0.0002

ILE 247 VAL 248 0.0003

VAL 248 VAL 249 0.0001

VAL 249 LEU 250 0.0001

LEU 250 SER 251 0.0122

SER 251 TRP 252 0.0002

TRP 252 VAL 253 -0.0000

VAL 253 SER 254 -0.0001

SER 254 PHE 255 -0.0000

PHE 255 TRP 256 -0.0000

TRP 256 ILE 257 0.0000

ILE 257 ASN 258 -0.0001

ASN 258 LYS 259 -0.0001

LYS 259 ASP 260 -0.0076

ASP 260 ALA 261 0.0003

ALA 261 VAL 262 -0.0001

VAL 262 PRO 263 0.0001

PRO 263 ALA 264 0.0003

ALA 264 ARG 265 -0.0001

ARG 265 THR 266 -0.0001

THR 266 SER 267 0.0002

SER 267 LEU 268 -0.0002

LEU 268 GLY 269 -0.0147

GLY 269 ILE 270 0.0002

ILE 270 THR 271 0.0001

THR 271 THR 272 0.0000

THR 272 VAL 273 -0.0001

VAL 273 LEU 274 -0.0000

LEU 274 THR 275 0.0006

THR 275 MET 276 -0.0002

MET 276 THR 277 -0.0006

THR 277 THR 278 0.0543

THR 278 LEU 279 0.0000

LEU 279 SER 280 -0.0001

SER 280 THR 281 0.0001

THR 281 ILE 282 0.0005

ILE 282 ALA 283 0.0001

ALA 283 ARG 284 -0.0000

ARG 284 LYS 285 -0.0002

LYS 285 SER 286 0.0002

SER 286 LEU 287 -0.0737

LEU 287 PRO 288 -0.0003

PRO 288 LYS 289 -0.0000

LYS 289 VAL 290 -0.0001

VAL 290 SER 291 0.0001

SER 291 TYR 292 0.0003

TYR 292 VAL 293 0.0002

VAL 293 THR 294 -0.0004

THR 294 ALA 295 -0.0000

ALA 295 MET 296 -0.0037

MET 296 ASP 297 0.0002

ASP 297 LEU 298 -0.0001

LEU 298 PHE 299 -0.0001

PHE 299 VAL 300 -0.0001

VAL 300 SER 301 -0.0002

SER 301 VAL 302 0.0001

VAL 302 CYS 303 0.0002

CYS 303 PHE 304 0.0001

PHE 304 ILE 305 0.0258

ILE 305 PHE 306 -0.0002

PHE 306 VAL 307 0.0000

VAL 307 PHE 308 0.0001

PHE 308 SER 309 0.0000

SER 309 ALA 310 0.0000

ALA 310 LEU 311 0.0003

LEU 311 VAL 312 -0.0002

VAL 312 GLU 313 -0.0000

GLU 313 TYR 314 0.0152

TYR 314 GLY 315 0.0001

GLY 315 THR 316 0.0002

THR 316 LEU 317 0.0003

LEU 317 HIS 318 -0.0001

HIS 318 TYR 319 -0.0003

TYR 319 PHE 320 -0.0001

PHE 320 VAL 321 -0.0000

VAL 321 SER 322 -0.0000

SER 322 ASN 323 -0.0197

ASN 323 ARG 324 -0.0000

ARG 324 ARG 406 -0.0140

ARG 406 ILE 407 -0.0005

ILE 407 ALA 408 0.0002

ALA 408 LYS 409 -0.0003

LYS 409 MET 410 -0.0005

MET 410 ASP 411 -0.0001

ASP 411 SER 412 0.0002

SER 412 TYR 413 -0.0003

TYR 413 ALA 414 0.0002

ALA 414 ARG 415 0.0031

ARG 415 ILE 416 -0.0000

ILE 416 PHE 417 -0.0001

PHE 417 PHE 418 -0.0002

PHE 418 PRO 419 0.0000

PRO 419 THR 420 0.0001

THR 420 ALA 421 0.0002

ALA 421 PHE 422 0.0001

PHE 422 CYS 423 0.0001

CYS 423 LEU 424 -0.0002

LEU 424 PHE 425 0.0002

PHE 425 ASN 426 0.0001

ASN 426 LEU 427 -0.0002

LEU 427 VAL 428 0.0002

VAL 428 TYR 429 0.0003

TYR 429 TRP 430 0.0002

TRP 430 VAL 431 0.0001

VAL 431 SER 432 -0.0001

SER 432 TYR 433 -0.0228

TYR 433 LEU 434 -0.0001

LEU 434 TYR 435 0.0001

TYR 435 LEU 436 0.0002

LEU 436 THR 13 0.0130

THR 13 VAL 14 0.0003

VAL 14 PHE 15 -0.0001

PHE 15 THR 16 0.0003

THR 16 ARG 17 -0.0001

ARG 17 ILE 18 0.0000

ILE 18 LEU 19 -0.0003

LEU 19 ASP 20 0.0001

ASP 20 ARG 21 -0.0000

ARG 21 LEU 22 0.0190

LEU 22 LEU 23 -0.0000

LEU 23 ASP 24 0.0002

ASP 24 GLY 25 0.0003

GLY 25 TYR 26 -0.0001

TYR 26 ASP 27 -0.0000

ASP 27 ASN 28 0.0000

ASN 28 ARG 29 0.0002

ARG 29 LEU 30 0.0001

LEU 30 ARG 31 0.0271

ARG 31 PRO 32 -0.0002

PRO 32 GLY 33 -0.0005

GLY 33 LEU 34 -0.0001

LEU 34 GLY 35 -0.0001

GLY 35 GLU 36 0.0000

GLU 36 ARG 37 -0.0002

ARG 37 VAL 38 -0.0001

VAL 38 THR 39 0.0002

THR 39 GLU 40 0.0536

GLU 40 VAL 41 0.0005

VAL 41 LYS 42 0.0000

LYS 42 THR 43 -0.0001

THR 43 ASP 44 -0.0004

ASP 44 ILE 45 0.0004

ILE 45 PHE 46 -0.0002

PHE 46 VAL 47 -0.0000

VAL 47 THR 48 -0.0001

THR 48 SER 49 0.0280

SER 49 PHE 50 0.0002

PHE 50 GLY 51 0.0004

GLY 51 PRO 52 -0.0003

PRO 52 VAL 53 -0.0001

VAL 53 SER 54 0.0004

SER 54 ASP 55 0.0001

ASP 55 HIS 56 -0.0004

HIS 56 ASP 57 -0.0002

ASP 57 MET 58 0.0540

MET 58 GLU 59 0.0002

GLU 59 TYR 60 -0.0004

TYR 60 THR 61 0.0005

THR 61 ILE 62 0.0003

ILE 62 ASP 63 -0.0002

ASP 63 VAL 64 -0.0002

VAL 64 PHE 65 0.0001

PHE 65 PHE 66 0.0002

PHE 66 ARG 67 0.0588

ARG 67 GLN 68 0.0001

GLN 68 SER 69 -0.0003

SER 69 TRP 70 0.0001

TRP 70 LYS 71 -0.0001

LYS 71 ASP 72 0.0001

ASP 72 GLU 73 0.0001

GLU 73 ARG 74 0.0000

ARG 74 LEU 75 -0.0003

LEU 75 LYS 76 0.0121

LYS 76 PHE 77 0.0000

PHE 77 LYS 78 0.0002

LYS 78 GLY 79 -0.0001

GLY 79 PRO 80 0.0001

PRO 80 MET 81 -0.0003

MET 81 THR 82 -0.0000

THR 82 VAL 83 0.0000

VAL 83 LEU 84 -0.0000

LEU 84 ARG 85 0.0305

ARG 85 LEU 86 -0.0000

LEU 86 ASN 87 0.0000

ASN 87 ASN 88 0.0002

ASN 88 LEU 89 -0.0001

LEU 89 MET 90 -0.0001

MET 90 ALA 91 0.0001

ALA 91 SER 92 0.0001

SER 92 LYS 93 0.0003

LYS 93 ILE 94 -0.0087

ILE 94 TRP 95 0.0001

TRP 95 THR 96 -0.0002

THR 96 PRO 97 0.0000

PRO 97 ASP 98 0.0003

ASP 98 THR 99 0.0000

THR 99 PHE 100 0.0001

PHE 100 PHE 101 0.0002

PHE 101 HIS 102 0.0002

HIS 102 ASN 103 0.0298

ASN 103 GLY 104 0.0000

GLY 104 LYS 105 0.0003

LYS 105 LYS 106 -0.0002

LYS 106 SER 107 0.0001

SER 107 VAL 108 0.0005

VAL 108 ALA 109 -0.0003

ALA 109 HIS 110 0.0000

HIS 110 ASN 111 0.0000

ASN 111 MET 112 -0.0136

MET 112 THR 113 0.0004

THR 113 MET 114 0.0004

MET 114 PRO 115 0.0004

PRO 115 ASN 116 -0.0001

ASN 116 LYS 117 0.0005

LYS 117 LEU 118 -0.0002

LEU 118 LEU 119 0.0002

LEU 119 ARG 120 0.0001

ARG 120 ILE 121 0.0316

ILE 121 THR 122 0.0004

THR 122 GLU 123 -0.0001

GLU 123 ASP 124 -0.0001

ASP 124 GLY 125 -0.0001

GLY 125 THR 126 0.0002

THR 126 LEU 127 0.0001

LEU 127 LEU 128 -0.0003

LEU 128 TYR 129 0.0003

TYR 129 THR 130 0.0341

THR 130 MET 131 0.0001

MET 131 ARG 132 -0.0003

ARG 132 LEU 133 -0.0001

LEU 133 THR 134 0.0000

THR 134 VAL 135 -0.0000

VAL 135 ARG 136 0.0000

ARG 136 ALA 137 -0.0001

ALA 137 GLU 138 0.0000

GLU 138 CYS 139 -0.0669

CYS 139 PRO 140 0.0002

PRO 140 MET 141 -0.0003

MET 141 HIS 142 -0.0000

HIS 142 LEU 143 -0.0001

LEU 143 GLU 144 0.0003

GLU 144 ASP 145 -0.0002

ASP 145 PHE 146 0.0002

PHE 146 PRO 147 0.0004

PRO 147 MET 148 0.0062

MET 148 ASP 149 0.0000

ASP 149 ALA 150 0.0001

ALA 150 HIS 151 -0.0001

HIS 151 ALA 152 0.0000

ALA 152 CYS 153 0.0003

CYS 153 PRO 154 0.0001

PRO 154 LEU 155 0.0000

LEU 155 LYS 156 0.0002

LYS 156 PHE 157 0.0283

PHE 157 GLY 158 0.0001

GLY 158 SER 159 0.0002

SER 159 TYR 160 0.0001

TYR 160 ALA 161 -0.0001

ALA 161 TYR 162 -0.0001

TYR 162 THR 163 0.0005

THR 163 ARG 164 -0.0001

ARG 164 ALA 165 -0.0000

ALA 165 GLU 166 -0.0059

GLU 166 VAL 167 0.0003

VAL 167 VAL 168 -0.0002

VAL 168 TYR 169 0.0000

TYR 169 GLU 170 0.0000

GLU 170 TRP 171 0.0001

TRP 171 THR 172 -0.0001

THR 172 ARG 173 -0.0001

ARG 173 GLU 174 0.0000

GLU 174 PRO 175 0.0300

PRO 175 ALA 176 -0.0002

ALA 176 ARG 177 -0.0002

ARG 177 SER 178 0.0001

SER 178 VAL 179 -0.0001

VAL 179 VAL 180 -0.0003

VAL 180 VAL 181 -0.0001

VAL 181 ALA 182 -0.0003

ALA 182 GLU 183 -0.0001

GLU 183 ASP 184 0.0260

ASP 184 GLY 185 -0.0004

GLY 185 SER 186 0.0002

SER 186 ARG 187 -0.0004

ARG 187 LEU 188 -0.0001

LEU 188 ASN 189 0.0003

ASN 189 GLN 190 0.0001

GLN 190 TYR 191 0.0002

TYR 191 ASP 192 -0.0000

ASP 192 LEU 193 0.1212

LEU 193 LEU 194 0.0002

LEU 194 GLY 195 0.0001

GLY 195 GLN 196 -0.0004

GLN 196 THR 197 0.0002

THR 197 VAL 198 -0.0002

VAL 198 ASP 199 0.0000

ASP 199 SER 200 -0.0001

SER 200 GLY 201 -0.0001

GLY 201 ILE 202 0.0083

ILE 202 VAL 203 0.0001

VAL 203 GLN 204 0.0000

GLN 204 SER 205 0.0001

SER 205 SER 206 -0.0001

SER 206 THR 207 0.0001

THR 207 GLY 208 0.0002

GLY 208 GLU 209 -0.0005

GLU 209 TYR 210 0.0003

TYR 210 VAL 211 0.0384

VAL 211 VAL 212 0.0000

VAL 212 MET 213 -0.0002

MET 213 THR 214 0.0001

THR 214 THR 215 -0.0000

THR 215 HIS 216 -0.0000

HIS 216 PHE 217 0.0002

PHE 217 HIS 218 -0.0002

HIS 218 LEU 219 -0.0001

LEU 219 LYS 220 0.1005

LYS 220 ARG 221 0.0000

ARG 221 LYS 222 -0.0002

LYS 222 ILE 223 0.0003

ILE 223 GLY 224 0.0002

GLY 224 TYR 225 0.0000

TYR 225 PHE 226 0.0002

PHE 226 VAL 227 0.0003

VAL 227 ILE 228 0.0002

ILE 228 GLN 229 0.0014

GLN 229 THR 230 0.0004

THR 230 TYR 231 -0.0002

TYR 231 LEU 232 -0.0001

LEU 232 PRO 233 -0.0001

PRO 233 CYS 234 -0.0001

CYS 234 ILE 235 0.0004

ILE 235 MET 236 0.0003

MET 236 THR 237 0.0001

THR 237 VAL 238 -0.0135

VAL 238 ILE 239 0.0001

ILE 239 LEU 240 0.0002

LEU 240 SER 241 0.0002

SER 241 GLN 242 -0.0000

GLN 242 VAL 243 -0.0002

VAL 243 SER 244 -0.0001

SER 244 PHE 245 0.0003

PHE 245 TRP 246 -0.0001

TRP 246 LEU 247 -0.0278

LEU 247 ASN 248 -0.0000

ASN 248 ARG 249 0.0001

ARG 249 GLU 250 -0.0001

GLU 250 SER 251 0.0001

SER 251 VAL 252 -0.0000

VAL 252 PRO 253 -0.0000

PRO 253 ALA 254 0.0001

ALA 254 ARG 255 -0.0000

ARG 255 THR 256 -0.0093

THR 256 VAL 257 0.0004

VAL 257 PHE 258 -0.0000

PHE 258 GLY 259 -0.0001

GLY 259 VAL 260 0.0000

VAL 260 THR 261 0.0000

THR 261 THR 262 -0.0001

THR 262 VAL 263 -0.0001

VAL 263 LEU 264 -0.0000

LEU 264 THR 265 0.0628

THR 265 MET 266 0.0002

MET 266 THR 267 0.0000

THR 267 THR 268 0.0004

THR 268 LEU 269 -0.0003

LEU 269 SER 270 -0.0001

SER 270 ILE 271 0.0000

ILE 271 SER 272 0.0000

SER 272 ALA 273 -0.0000

ALA 273 ARG 274 -0.0432

ARG 274 ASN 275 0.0000

ASN 275 SER 276 0.0001

SER 276 LEU 277 0.0000

LEU 277 PRO 278 -0.0001

PRO 278 LYS 279 0.0005

LYS 279 VAL 280 -0.0000

VAL 280 ALA 281 -0.0003

ALA 281 TYR 282 -0.0000

TYR 282 ALA 283 -0.1991

ALA 283 THR 284 0.0002

THR 284 ALA 285 -0.0002

ALA 285 MET 286 -0.0000

MET 286 ASP 287 0.0000

ASP 287 TRP 288 -0.0001

TRP 288 PHE 289 -0.0000

PHE 289 ILE 290 -0.0001

ILE 290 ALA 291 -0.0000

ALA 291 VAL 292 -0.0763

VAL 292 CYS 293 -0.0001

CYS 293 TYR 294 -0.0001

TYR 294 ALA 295 -0.0002

ALA 295 PHE 296 0.0001

PHE 296 VAL 297 -0.0001

VAL 297 PHE 298 0.0000

PHE 298 SER 299 -0.0005

SER 299 ALA 300 -0.0002

ALA 300 LEU 301 0.0204

LEU 301 ILE 302 0.0004

ILE 302 GLU 303 0.0003

GLU 303 PHE 304 -0.0000

PHE 304 ALA 305 0.0000

ALA 305 THR 306 -0.0000

THR 306 VAL 307 -0.0003

VAL 307 ASN 308 -0.0000

ASN 308 TYR 309 -0.0001

TYR 309 PHE 310 -0.0093

PHE 310 THR 311 0.0001

THR 311 LYS 312 0.0000

LYS 312 ARG 313 0.0001

ARG 313 GLY 314 0.0002

GLY 314 TYR 315 0.0000

TYR 315 ALA 316 0.0002

ALA 316 TRP 317 -0.0000

TRP 317 ASP 318 0.0001

ASP 318 GLY 319 0.0201

GLY 319 LYS 320 0.0000

LYS 320 LYS 384 0.0099

LYS 384 THR 385 -0.0001

THR 385 PHE 386 0.0001

PHE 386 ASN 387 -0.0000

ASN 387 SER 388 0.0000

SER 388 VAL 389 -0.0001

VAL 389 SER 390 -0.0004

SER 390 LYS 391 -0.0002

LYS 391 ILE 392 0.0002

ILE 392 ASP 393 0.0256

ASP 393 ARG 394 0.0002

ARG 394 LEU 395 0.0001

LEU 395 SER 396 -0.0003

SER 396 ARG 397 -0.0004

ARG 397 ILE 398 -0.0000

ILE 398 ALA 399 -0.0000

ALA 399 PHE 400 -0.0004

PHE 400 PRO 401 -0.0003

PRO 401 LEU 402 -0.0021

LEU 402 LEU 403 0.0001

LEU 403 PHE 404 -0.0000

PHE 404 GLY 405 0.0001

GLY 405 ILE 406 -0.0001

ILE 406 PHE 407 -0.0002

PHE 407 ASN 408 -0.0001

ASN 408 LEU 409 0.0004

LEU 409 VAL 410 0.0002

VAL 410 TYR 411 -0.0788

TYR 411 TRP 412 0.0003

TRP 412 ALA 413 -0.0001

ALA 413 THR 414 0.0002

THR 414 TYR 415 -0.0003

TYR 415 LEU 416 -0.0001

LEU 416 ASN 417 -0.0003

ASN 417 ARG 418 0.0001

ARG 418 ASN 8 -0.0277

ASN 8 MET 9 -0.0000

MET 9 SER 10 -0.0003

SER 10 PHE 11 0.0000

PHE 11 VAL 12 0.0002

VAL 12 LYS 13 -0.0002

LYS 13 GLU 14 -0.0003

GLU 14 THR 15 -0.0000

THR 15 VAL 16 -0.0002

VAL 16 ASP 17 -0.0027

ASP 17 LYS 18 -0.0002

LYS 18 LEU 19 -0.0001

LEU 19 LEU 20 0.0004

LEU 20 LYS 21 0.0000

LYS 21 GLY 22 -0.0003

GLY 22 TYR 23 0.0000

TYR 23 ASP 24 0.0001

ASP 24 ILE 25 0.0001

ILE 25 ARG 26 -0.0192

ARG 26 LEU 27 -0.0003

LEU 27 ARG 28 0.0000

ARG 28 PRO 29 -0.0001

PRO 29 ASP 30 -0.0000

ASP 30 PHE 31 0.0000

PHE 31 GLY 32 -0.0000

GLY 32 GLY 33 0.0001

GLY 33 PRO 34 0.0001

PRO 34 PRO 35 0.0189

PRO 35 VAL 36 -0.0002

VAL 36 CYS 37 0.0004

CYS 37 VAL 38 0.0003

VAL 38 GLY 39 -0.0004

GLY 39 MET 40 0.0000

MET 40 ASN 41 -0.0000

ASN 41 ILE 42 0.0000

ILE 42 ASP 43 -0.0002

ASP 43 ILE 44 -0.0399

ILE 44 ALA 45 0.0002

ALA 45 SER 46 0.0003

SER 46 ILE 47 0.0002

ILE 47 ASP 48 -0.0002

ASP 48 MET 49 0.0002

MET 49 VAL 50 -0.0003

VAL 50 SER 51 0.0003

SER 51 GLU 52 -0.0002

GLU 52 VAL 53 0.0165

VAL 53 ASN 54 -0.0001

ASN 54 MET 55 0.0002

MET 55 ASP 56 -0.0000

ASP 56 TYR 57 0.0001

TYR 57 THR 58 -0.0002

THR 58 LEU 59 0.0002

LEU 59 THR 60 0.0001

THR 60 MET 61 0.0005

MET 61 TYR 62 -0.1024

TYR 62 PHE 63 0.0004

PHE 63 GLN 64 -0.0001

GLN 64 GLN 65 0.0002

GLN 65 TYR 66 0.0000

TYR 66 TRP 67 -0.0002

TRP 67 ARG 68 0.0002

ARG 68 ASP 69 -0.0004

ASP 69 LYS 70 0.0003

LYS 70 ARG 71 0.0107

ARG 71 LEU 72 0.0001

LEU 72 ALA 73 0.0000

ALA 73 TYR 74 -0.0001

TYR 74 SER 75 -0.0002

SER 75 GLY 76 -0.0000

GLY 76 ILE 77 0.0001

ILE 77 PRO 78 -0.0001

PRO 78 LEU 79 0.0005

LEU 79 ASN 80 -0.0080

ASN 80 LEU 81 0.0004

LEU 81 THR 82 0.0003

THR 82 LEU 83 0.0001

LEU 83 ASP 84 -0.0002

ASP 84 ASN 85 0.0002

ASN 85 ARG 86 -0.0000

ARG 86 VAL 87 0.0001

VAL 87 ALA 88 -0.0002

ALA 88 ASP 89 -0.0116

ASP 89 GLN 90 0.0003

GLN 90 LEU 91 0.0002

LEU 91 TRP 92 -0.0001

TRP 92 VAL 93 -0.0001

VAL 93 PRO 94 0.0003

PRO 94 ASP 95 -0.0002

ASP 95 THR 96 0.0001

THR 96 TYR 97 0.0004

TYR 97 PHE 98 -0.0056

PHE 98 LEU 99 -0.0003

LEU 99 ASN 100 0.0001

ASN 100 ASP 101 0.0000

ASP 101 LYS 102 0.0000

LYS 102 LYS 103 -0.0000

LYS 103 SER 104 0.0001

SER 104 PHE 105 0.0002

PHE 105 VAL 106 -0.0002

VAL 106 HIS 107 -0.0220

HIS 107 GLY 108 -0.0002

GLY 108 VAL 109 0.0004

VAL 109 THR 110 -0.0001

THR 110 VAL 111 0.0004

VAL 111 LYS 112 -0.0003

LYS 112 ASN 113 -0.0002

ASN 113 ARG 114 0.0001

ARG 114 MET 115 -0.0002

MET 115 ILE 116 0.0723

ILE 116 ARG 117 0.0001

ARG 117 LEU 118 -0.0004

LEU 118 HIS 119 0.0003

HIS 119 PRO 120 0.0000

PRO 120 ASP 121 0.0003

ASP 121 GLY 122 -0.0004

GLY 122 THR 123 -0.0001

THR 123 VAL 124 0.0004

VAL 124 LEU 125 -0.0104

LEU 125 TYR 126 0.0002

TYR 126 GLY 127 -0.0000

GLY 127 LEU 128 -0.0000

LEU 128 ARG 129 -0.0002

ARG 129 ILE 130 -0.0001

ILE 130 THR 131 -0.0002

THR 131 THR 132 0.0005

THR 132 THR 133 -0.0001

THR 133 ALA 134 -0.0999

ALA 134 ALA 135 0.0001

ALA 135 CYS 136 -0.0004

CYS 136 MET 137 0.0004

MET 137 MET 138 0.0003

MET 138 ASP 139 -0.0002

ASP 139 LEU 140 -0.0002

LEU 140 ARG 141 0.0002

ARG 141 ARG 142 0.0000

ARG 142 TYR 143 0.0482

TYR 143 PRO 144 -0.0002

PRO 144 LEU 145 0.0001

LEU 145 ASP 146 -0.0004

ASP 146 GLU 147 0.0001

GLU 147 GLN 148 0.0001

GLN 148 ASN 149 -0.0002

ASN 149 CYS 150 -0.0004

CYS 150 THR 151 -0.0000

THR 151 LEU 152 0.0291

LEU 152 GLU 153 0.0001

GLU 153 ILE 154 0.0001

ILE 154 GLU 155 0.0001

GLU 155 SER 156 -0.0000

SER 156 TYR 157 -0.0000

TYR 157 GLY 158 0.0003

GLY 158 TYR 159 -0.0002

TYR 159 THR 160 -0.0001

THR 160 THR 161 -0.0278

THR 161 ASP 162 -0.0000

ASP 162 ASP 163 0.0000

ASP 163 ILE 164 -0.0002

ILE 164 GLU 165 0.0002

GLU 165 PHE 166 -0.0002

PHE 166 TYR 167 -0.0003

TYR 167 TRP 168 0.0003

TRP 168 ARG 169 0.0000

ARG 169 GLY 170 -0.0132

GLY 170 GLY 171 -0.0001

GLY 171 ASP 172 0.0002

ASP 172 LYS 173 -0.0003

LYS 173 ALA 174 -0.0000

ALA 174 VAL 175 0.0003

VAL 175 THR 176 -0.0001

THR 176 GLY 177 0.0001

GLY 177 VAL 178 -0.0000

VAL 178 GLU 179 -0.0078

GLU 179 ARG 180 -0.0001

ARG 180 ILE 181 0.0001

ILE 181 GLU 182 -0.0004

GLU 182 LEU 183 0.0000

LEU 183 PRO 184 0.0002

PRO 184 GLN 185 0.0003

GLN 185 PHE 186 0.0002

PHE 186 SER 187 -0.0004

SER 187 ILE 188 0.1267

ILE 188 VAL 189 0.0002

VAL 189 GLU 190 -0.0005

GLU 190 HIS 191 -0.0001

HIS 191 ARG 192 0.0002

ARG 192 LEU 193 0.0003

LEU 193 VAL 194 -0.0001

VAL 194 SER 195 -0.0000

SER 195 ARG 196 0.0004

ARG 196 ASN 197 0.0281

ASN 197 VAL 198 -0.0000

VAL 198 VAL 199 0.0002

VAL 199 PHE 200 0.0000

PHE 200 ALA 201 0.0004

ALA 201 THR 202 -0.0001

THR 202 GLY 203 0.0000

GLY 203 ALA 204 0.0002

ALA 204 TYR 205 0.0001

TYR 205 PRO 206 -0.0087

PRO 206 ARG 207 0.0001

ARG 207 LEU 208 -0.0000

LEU 208 SER 209 0.0002

SER 209 LEU 210 0.0001

LEU 210 SER 211 -0.0000

SER 211 PHE 212 -0.0004

PHE 212 ARG 213 0.0005

ARG 213 LEU 214 -0.0004

LEU 214 LYS 215 0.0986

LYS 215 ARG 216 -0.0000

ARG 216 ASN 217 0.0001

ASN 217 ILE 218 -0.0000

ILE 218 GLY 219 -0.0001

GLY 219 TYR 220 -0.0001

TYR 220 PHE 221 0.0001

PHE 221 ILE 222 -0.0002

ILE 222 LEU 223 -0.0002

LEU 223 GLN 224 0.0578

GLN 224 THR 225 0.0002

THR 225 TYR 226 0.0001

TYR 226 MET 227 -0.0003

MET 227 PRO 228 -0.0001

PRO 228 SER 229 -0.0003

SER 229 ILE 230 -0.0001

ILE 230 LEU 231 -0.0001

LEU 231 ILE 232 0.0003

ILE 232 THR 233 -0.0284

THR 233 ILE 234 0.0001

ILE 234 LEU 235 0.0004

LEU 235 SER 236 -0.0004

SER 236 TRP 237 0.0002

TRP 237 VAL 238 0.0003

VAL 238 SER 239 0.0001

SER 239 PHE 240 -0.0004

PHE 240 TRP 241 0.0000

TRP 241 ILE 242 -0.0090

ILE 242 ASN 243 0.0001

ASN 243 TYR 244 -0.0001

TYR 244 ASP 245 0.0001

ASP 245 ALA 246 -0.0002

ALA 246 SER 247 -0.0003

SER 247 ALA 248 -0.0001

ALA 248 ALA 249 -0.0000

ALA 249 ARG 250 0.0002

ARG 250 VAL 251 -0.0027

VAL 251 ALA 252 -0.0001

ALA 252 LEU 253 0.0001

LEU 253 GLY 254 -0.0001

GLY 254 ILE 255 0.0000

ILE 255 THR 256 0.0002

THR 256 THR 257 0.0002

THR 257 VAL 258 -0.0003

VAL 258 LEU 259 0.0002

LEU 259 THR 260 -0.0160

THR 260 MET 261 0.0000

MET 261 THR 262 0.0001

THR 262 THR 263 -0.0002

THR 263 ILE 264 -0.0001

ILE 264 ASN 265 -0.0004

ASN 265 THR 266 0.0004

THR 266 HIS 267 0.0003

HIS 267 LEU 268 0.0002

LEU 268 ARG 269 0.0915

ARG 269 GLU 270 -0.0000

GLU 270 THR 271 -0.0000

THR 271 LEU 272 0.0001

LEU 272 PRO 273 -0.0001

PRO 273 LYS 274 -0.0001

LYS 274 ILE 275 0.0002

ILE 275 PRO 276 0.0003

PRO 276 TYR 277 -0.0003

TYR 277 VAL 278 0.0785

VAL 278 LYS 279 -0.0002

LYS 279 ALA 280 0.0000

ALA 280 ILE 281 -0.0004

ILE 281 ASP 282 0.0001

ASP 282 MET 283 0.0001

MET 283 TYR 284 -0.0001

TYR 284 LEU 285 -0.0001

LEU 285 MET 286 0.0001

MET 286 GLY 287 -0.0212

GLY 287 CYS 288 0.0001

CYS 288 PHE 289 -0.0002

PHE 289 VAL 290 0.0001

VAL 290 PHE 291 -0.0003

PHE 291 VAL 292 -0.0002

VAL 292 PHE 293 0.0000

PHE 293 LEU 294 -0.0002

LEU 294 ALA 295 -0.0004

ALA 295 LEU 296 -0.0087

LEU 296 LEU 297 -0.0000

LEU 297 GLU 298 -0.0004

GLU 298 TYR 299 -0.0001

TYR 299 ALA 300 0.0002

ALA 300 PHE 301 -0.0004

PHE 301 VAL 302 0.0005

VAL 302 ASN 303 0.0000

ASN 303 TYR 304 -0.0001

TYR 304 ILE 305 -0.0161

ILE 305 PHE 306 -0.0001

PHE 306 PHE 307 -0.0001

PHE 307 GLY 308 -0.0002

GLY 308 ARG 309 0.0004

ARG 309 GLY 310 -0.0001

GLY 310 PRO 311 0.0003

PRO 311 GLN 312 -0.0000

GLN 312 ASP 419 -0.0034

ASP 419 VAL 420 -0.0003

VAL 420 ASN 421 -0.0002

ASN 421 ALA 422 -0.0003

ALA 422 ILE 423 -0.0000

ILE 423 ASP 424 -0.0001

ASP 424 ARG 425 -0.0000

ARG 425 TRP 426 0.0002

TRP 426 SER 427 -0.0001

SER 427 ARG 428 -0.0026

ARG 428 ILE 429 -0.0001

ILE 429 VAL 430 -0.0000

VAL 430 PHE 431 -0.0000

PHE 431 PRO 432 0.0001

PRO 432 PHE 433 0.0003

PHE 433 THR 434 -0.0001

THR 434 PHE 435 0.0000

PHE 435 SER 436 0.0002

SER 436 LEU 437 0.0198

LEU 437 PHE 438 -0.0002

PHE 438 ASN 439 0.0002

ASN 439 LEU 440 0.0003

LEU 440 VAL 441 -0.0002

VAL 441 TYR 442 0.0001

TYR 442 TRP 443 0.0002

TRP 443 LEU 444 0.0001

LEU 444 TYR 445 0.0002

TYR 445 TYR 446 -0.0352

TYR 446 VAL 447 0.0000

VAL 447 GLY 4 0.0112

GLY 4 VAL 3 0.0211

VAL 3 GLY 2 0.0002

GLY 2 ALA 1 -0.0067

ALA 1 GLY 4 0.0126

GLY 4 VAL 3 -0.0118

VAL 3 GLY 2 0.0003

GLY 2 ALA 1 -0.0031

If you find results from this site helpful for your research, please cite one of our papers:

K. Suhre & Y.H. Sanejouand, ElNemo: a normal mode web-server for protein movement analysis and the generation of templates for molecular replacement. Nucleic Acids Research, 32, W610-W614, 2004.
K. Suhre & Y.H. Sanejouand, On the potential of normal mode analysis for solving difficult molecular replacement problems. Acta Cryst. D vol.60, p796-799, 2004 © International Union of Crystallography.

elNémo is maintained by Yves-Henri Sanejouand.
It was developed by Karsten Suhre.
Between 2003 and 2014, it was hosted by IGS (Marseille).
Last modification: October 18th, 2018.

Should you encounter any unexpected behaviour, please let us know.

*** Model 4A ***

CA strain for 21020920311728206

--- normal mode 12 ---

Should you encounter any unexpected behaviour,
please let us know.

* Model 4A *